D:Bacterial Meningitis

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Disease Term
Synonyms Acute Bacterial Meningitis, Bacterial Meningitides, Meningitides Bacterial, Meningitis Bacterial, Meningitis Due To Unspecified Bacterium, Meningococci, Meningococcus, Neisseria Meningitidis, Neonatal Meningitis, Pneumococcal Disease, Pneumococci
Documents 824
Hot Single Events 200
Hot Interactions 15

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Bacterial Meningitis. They are ordered first by their relevance to Bacterial Meningitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT220724 Binding of IGFALS and SOD1 1 0.06 2.1 0.06 99.84
2 INT168792 Negative_regulation of Binding of AGFG1 and IVNS1ABP 1 0.01 0.39 0.26 99.84
3 INT220725 Binding of IGFALS and IGHD1OR15-1A 1 0.01 1.05 0.03 99.84
4 INT170656 Ntf3 Positive_regulation of Csf2 1 0.35 1.46 0.44 99.20
5 INT168791 Positive_regulation of Binding of AGFG1 and IVNS1ABP 1 0.01 0.39 0.26 98.52
6 INT168790 Binding of AGFG1 and IVNS1ABP 1 0.01 0.39 0.26 98.52
7 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 94.40
8 INT220305 Binding of IL6 and IL10 1 0.00 0.51 0.14 90.88
9 INT314534 Ptger2 Regulation of Gene_expression of Itgam 1 0.02 1 0.17 90.88
10 INT199041 AGRP Regulation of IGHE 1 0.00 1.39 0.03 90.32
11 INT228137 Binding of Serpinb1-ps1 and Trav6-3 2 0.02 1.93 0.08 84.04
12 INT294757 Binding of Dob1 and Serpinb1-ps1 1 0.00 0.72 0.08 82.52
13 INT282712 Binding of MUC5AC and Csf2 1 0.01 2.63 1.07 82.24
14 INT282713 Binding of MUC5AC and Mmp9 1 0.02 1.27 0.52 82.24
15 INT282711 Binding of Csf2 and Mmp9 1 0.16 1.35 0.54 81.04
16 INT298052 Binding of Cd74 and Vip 1 0.00 1.05 0.13 79.36
17 INT287438 HTS Negative_regulation of Nfkb1 1 0.01 1.77 0.37 78.48
18 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28 69.92
19 INT228212 Cpox Negative_regulation of Localization of Ptger2 1 0.00 0.88 0.04 69.08
20 INT314536 Positive_regulation of Ptger2 Positive_regulation of Gene_expression of Il10 1 0.02 0.83 0.04 66.24
21 INT314539 Ptger2 Positive_regulation of Gene_expression of Il10 1 0.04 0.83 0.04 66.24
22 INT228213 Gopc Positive_regulation of Gene_expression of Ptger2 1 0.00 1.08 0 65.92
23 INT246439 Hand1 Positive_regulation of Gene_expression of Cd79a 1 0.04 0.78 0.27 64.08
24 INT228214 Nfkb1 Positive_regulation of Gene_expression of Ptger2 1 0.01 0.97 0 64.08
25 INT246442 Hand2 Positive_regulation of Gene_expression of Cd79a 1 0.03 0.78 0.27 63.76
26 INT298050 Binding of Bpifa2 and Ad 1 0.00 1.09 0.07 60.72
27 INT246435 Xcl1 Positive_regulation of Gene_expression of Cd79a 1 0.07 0.83 0.27 58.88
28 INT246438 Ccl5 Positive_regulation of Gene_expression of Cd79a 1 0.13 0.83 0.26 58.52
29 INT212527 Binding of PROC and Crp 1 0.00 1.5 0 58.36
30 INT212524 Binding of Crp and Ighm 1 0.02 0.92 0 58.36
31 INT325532 Binding of Cx3cl1 and Cxcl10 1 0.28 0.67 0.16 56.32
32 INT314538 Il10 Negative_regulation of Gene_expression of Ptger2 1 0.02 0.65 0.04 55.92
33 INT212522 Binding of Crp and Cd209a 1 0.00 0.8 0 55.88
34 INT212526 Binding of PROC and Apcs 1 0.01 2.54 0 49.76
35 INT283428 Negative_regulation of Binding of Lcn2 and Nt5e 1 0.06 1.09 0.15 48.96
36 INT283432 Lcn2 Negative_regulation of Binding of Lcn2 and Nt5e 1 0.07 0.38 0 45.36
37 INT306452 Binding of MBL2 and TLR4 1 0.38 0.37 0.1 45.16
38 INT306453 MBL2 Regulation of Binding of TLR4 1 0.48 0.37 0.1 45.16
39 INT283426 Binding of Lcn2 and Nt5e 1 0.08 5.8 1.24 43.84
40 INT353619 Positive_regulation of Mapk8 Positive_regulation of Gene_expression of Muc5ac 1 0.51 0.3 0 43.72
41 INT331576 IFN1@ Positive_regulation of TNFSF10 1 0.00 0.27 0.08 43.60
42 INT331575 Negative_regulation of IFN1@ Positive_regulation of TNFSF10 1 0.00 0.27 0.08 43.60
43 INT136096 Binding of CFH and CFI 1 0.04 2.28 0.05 34.08
44 INT298057 Vip Positive_regulation of Localization of IFN1@ 1 0.02 0.41 0.09 27.56
45 INT267618 Il1 Positive_regulation of Vcam1 1 0.00 0.81 0.09 26.40
46 INT212528 Binding of MSH6 and Apcs 1 0.00 0.68 0 24.80
47 INT267626 Il1 Positive_regulation of ICAM1 1 0.00 0.79 0.09 23.36
48 INT228216 Positive_regulation of Mapk14 Regulation of Gene_expression of Tlr2 1 0.09 1.11 0.15 20.48
49 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 18.64
50 INT244232 Binding of Ccr5 and Ccl4 3 0.17 1.48 0.55 18.64
51 INT298059 Binding of HLA-A and Vip 1 0.00 0.97 0.12 18.24
52 INT326404 Binding of Cck and Enpep 1 0.01 0.19 0.23 14.72
53 INT293868 Binding of GREM1 and OCM 1 0.00 1.11 0 7.36
54 INT293869 Binding of COL2A1 and GREM1 1 0.00 1.11 0 6.16
55 INT122567 Mog Positive_regulation of Eae1 8 0.31 10.18 4.26 5.00
56 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66 5.00
57 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
58 INT243043 Binding of Mmp9 and Timp1 1 0.05 0.25 1.86 5.00
59 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68 5.00
60 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 5.00
61 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54 5.00
62 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
63 INT170655 Binding of Csf2 and Ngf 1 0.36 1.25 1.18 5.00
64 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11 5.00
65 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1 5.00
66 INT170653 Ngf Regulation of Csf2 1 0.34 1.11 1.05 5.00
67 INT243044 Mmp8 Regulation of Mmp9 1 0.05 1.45 0.91 5.00
68 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
69 INT170658 Binding of Ntf3 and Csf2 1 0.33 0.8 0.74 5.00
70 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73 5.00
71 INT267630 Il1 Regulation of Gene_expression of IL8 1 0.00 0.44 0.71 5.00
72 INT211105 Binding of CRS and IGHE 1 0.02 3.63 0.66 5.00
73 INT267625 Binding of KNG1 and Klk1 2 0.21 2.23 0.61 5.00
74 INT254637 Bdkrb2 Regulation of Gene_expression of Ccl5 1 0.17 1.22 0.56 5.00
75 INT171905 TNF Positive_regulation of Gene_expression of Il1 2 0.23 1.08 0.54 5.00
76 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52 5.00
77 INT274170 Il13 Regulation of Il4 3 0.09 2.75 0.51 5.00
78 INT283434 Lcn2 Positive_regulation of Localization of IL8 1 0.07 1.33 0.51 5.00
79 INT254638 Bdkrb2 Positive_regulation of Positive_regulation of Bdkrb1 1 0.09 0.96 0.48 5.00
80 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
81 INT331731 Binding of C3 and CD79A 1 0.02 0.85 0.46 5.00
82 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46 5.00
83 INT254636 Bdkrb2 Regulation of Gene_expression of Ccl2 1 0.15 1.15 0.43 5.00
84 INT170657 Ntf3 Regulation of Csf2 1 0.31 0.46 0.43 5.00
85 INT316063 Ps Positive_regulation of IL8 1 0.09 1.33 0.41 5.00
86 INT316065 Eif1 Positive_regulation of IL8 1 0.01 1.34 0.41 5.00
87 INT204893 Regulation of Tlr4 Positive_regulation of gr 1 0.11 0.9 0.38 5.00
88 INT204905 Tlr4 Positive_regulation of gr 1 0.18 0.9 0.38 5.00
89 INT267585 TNF Regulation of IL6 2 0.16 2.44 0.37 5.00
90 INT267595 IL12A Positive_regulation of IFN1@ 1 0.03 0.69 0.36 5.00
91 INT183786 IL6 Negative_regulation of INS 1 0.09 1.61 0.35 5.00
92 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34 5.00
93 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34 5.00
94 INT183793 INS Negative_regulation of Binding of Ros1 1 0.16 1.66 0.34 5.00
95 INT183785 INS Positive_regulation of Gene_expression of NFKBIB 1 0.03 1.83 0.34 5.00
96 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34 5.00
97 INT183780 INS Negative_regulation of Gene_expression of CYBB 1 0.02 1.74 0.34 5.00
98 INT267589 IL2 Positive_regulation of Gene_expression of IL12A 1 0.01 0.69 0.34 5.00
99 INT300727 IL25 Positive_regulation of IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
100 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
101 INT269962 Bcl2 Negative_regulation of Bcl2l11 1 0.15 2.14 0.34 5.00
102 INT183782 INS Negative_regulation of Gene_expression of TBK1 1 0.01 1.81 0.34 5.00
103 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33 5.00
104 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33 5.00
105 INT294762 Il4 Regulation of Il13 2 0.09 0.92 0.32 5.00
106 INT238895 Binding of CRP and INS 1 0.00 0.93 0.32 5.00
107 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3 5.00
108 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3 5.00
109 INT130128 Binding of Ocln and Tjp1 2 0.38 0.98 0.29 5.00
110 INT193479 TLR2 Regulation of Binding of IRF6 1 0.04 0.75 0.28 5.00
111 INT329528 Seh1l Positive_regulation of Gene_expression of Csf2 1 0.07 0.37 0.28 5.00
112 INT329529 Tnfaip8 Positive_regulation of Gene_expression of Csf2 1 0.07 0.35 0.28 5.00
113 INT267628 IL4 Positive_regulation of IgG 1 0.00 1.42 0.27 5.00
114 INT267586 IL4 Positive_regulation of IGHE 1 0.00 1.42 0.27 5.00
115 INT254635 Positive_regulation of Eae1 Positive_regulation of Gene_expression of Ccl2 1 0.15 1.07 0.27 5.00
116 INT224458 TNF Positive_regulation of Gene_expression of Nfkb1 2 0.34 1.47 0.26 5.00
117 INT267632 Il1 Positive_regulation of Gene_expression of PLA2G6 1 0.00 0.86 0.25 5.00
118 INT267624 Klk1 Positive_regulation of KNG1 1 0.05 0.52 0.25 5.00
119 INT267584 TNF Positive_regulation of Gene_expression of PLA2G6 1 0.08 0.87 0.25 5.00
120 INT267631 IRF6 Positive_regulation of Gene_expression of Il1 1 0.00 0.96 0.25 5.00
121 INT267596 KNG1 Positive_regulation of Gene_expression of PLA2G6 1 0.01 0.87 0.25 5.00
122 INT267591 CYSLTR1 Positive_regulation of Gene_expression of PLA2G6 1 0.00 0.87 0.25 5.00
123 INT267623 IL6 Positive_regulation of Crp 1 0.00 1.6 0.24 5.00
124 INT279503 Binding of C1s and C1ra 1 0.03 0.58 0.22 5.00
125 INT329530 Malt1 Positive_regulation of Positive_regulation of Nfkb1 1 0.06 0.48 0.22 5.00
126 INT331602 Binding of SSRP1 and Tlr4 1 0.03 0.9 0.21 5.00
127 INT316054 Eif1 Positive_regulation of Il6 1 0.00 0.78 0.21 5.00
128 INT316062 Ps Positive_regulation of Il6 1 0.04 0.77 0.21 5.00
129 INT348970 Binding of MOG and HAND1 1 0.03 1.28 0.2 5.00
130 INT282710 Mmp9 Regulation of Gene_expression of Csf2 1 0.15 0.16 0.2 5.00
131 INT283429 Nt5e Regulation of Gene_expression of Cxcr1 1 0.00 0.22 0.2 5.00
132 INT283431 Lcn2 Regulation of Gene_expression of Cxcr1 1 0.01 0.22 0.2 5.00
133 INT316064 Binding of RBPJ and Csl 1 0.16 0.33 0.2 5.00
134 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19 5.00
135 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19 5.00
136 INT279507 Serping1 Negative_regulation of Gene_expression of C3 1 0.03 1.12 0.19 5.00
137 INT279500 Serping1 Negative_regulation of Transcription of C3 1 0.03 1.12 0.19 5.00
138 INT267629 PTAFR Positive_regulation of Localization of Il1 1 0.00 1.32 0.18 5.00
139 INT190381 IL1A Regulation of Transcription of DEFB4A 1 0.06 0.93 0.18 5.00
140 INT193695 Il2 Positive_regulation of Ctla4 1 0.01 1.63 0.18 5.00
141 INT246437 Ccl5 Positive_regulation of Regulation of Hand1 1 0.19 0.76 0.17 5.00
142 INT267627 Il1 Positive_regulation of Gene_expression of TNF 1 0.02 0.45 0.17 5.00
143 INT300753 Binding of Cd28 and Positive_regulation of Transcription of IL13 1 0.00 0 0.17 5.00
144 INT331600 Il18 Regulation of IFN1@ 1 0.00 1.05 0.16 5.00
145 INT331601 Il10 Regulation of IFN1@ 1 0.00 1.05 0.16 5.00
146 INT298055 Binding of IFN1@ and Il10 1 0.19 1.07 0.16 5.00
147 INT298056 Binding of IFN1@ and Cd4 1 0.31 1.07 0.16 5.00
148 INT246440 Ccl5 Positive_regulation of Positive_regulation of Xcl1 1 0.27 1.28 0.16 5.00
149 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15 5.00
150 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15 5.00
151 INT294766 Cerk Regulation of Gene_expression of Hand2 1 0.13 0.32 0.15 5.00
152 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15 5.00
153 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15 5.00
154 INT294763 Binding of Gopc and Cerk 1 0.14 0.37 0.14 5.00
155 INT293867 Binding of COL2A1 and MEFV 1 0.01 0.52 0.14 5.00
156 INT294764 Binding of Hand2 and Cerk 1 0.17 0.31 0.14 5.00
157 INT355226 VEGFA Positive_regulation of Akt1 1 0.04 0.27 0.14 5.00
158 INT294761 Binding of Hand1 and Cerk 1 0.23 0.36 0.14 5.00
159 INT235546 Stat6 Positive_regulation of Positive_regulation of Hand2 1 0.02 0.9 0.14 5.00
160 INT193693 Binding of Myd88 and Pain1 1 0.14 0.82 0.13 5.00
161 INT316059 Ps Regulation of Binding of Cd4 1 0.06 0.86 0.13 5.00
162 INT316058 Ps Regulation of Binding of Cd8a 1 0.02 0.86 0.13 5.00
163 INT300731 IL10 Negative_regulation of Gene_expression of IGHE 1 0.03 0.23 0.13 5.00
164 INT294760 Cerk Positive_regulation of Hand2 1 0.23 0.16 0.12 5.00
165 INT193697 Apaf1 Positive_regulation of CASP9 1 0.02 1.84 0.12 5.00
166 INT294758 Regulation of Cerk Positive_regulation of Hand2 1 0.21 0.16 0.12 5.00
167 INT204883 gr Negative_regulation of Lcn2 1 0.07 0.15 0.11 5.00
168 INT204888 Binding of Cp and Tlr4 1 0.29 0.49 0.11 5.00
169 INT204882 gr Negative_regulation of Saa3 1 0.07 0.15 0.11 5.00
170 INT279511 Binding of Serping1 and C1ra 1 0.01 0.3 0.11 5.00
171 INT204878 Gem Positive_regulation of Tlr4 1 0.20 0.1 0.1 5.00
172 INT204901 Tnfsf9 Positive_regulation of Tlr4 1 0.27 0.1 0.1 5.00
173 INT190382 IL1A Regulation of Regulation of DEFB4A 1 0.06 0.57 0.1 5.00
174 INT204877 gr Negative_regulation of Serpina3n 1 0.23 0.15 0.1 5.00
175 INT204890 Cd83 Positive_regulation of Tlr4 1 0.25 0.1 0.1 5.00
176 INT267587 PTAFR Positive_regulation of Localization of PTPRC 1 0.00 2.04 0.09 5.00
177 INT204897 Tlr4 Positive_regulation of Il1b 1 0.21 0.09 0.09 5.00
178 INT204898 Negative_regulation of Tlr4 Negative_regulation of Ch25h 1 0.21 0.09 0.09 5.00
179 INT204886 Tlr4 Negative_regulation of Negative_regulation of C1qa 1 0.21 0.09 0.09 5.00
180 INT204894 Tlr4 Positive_regulation of Ch25h 1 0.23 0.09 0.09 5.00
181 INT204899 Tlr4 Positive_regulation of Cd44 1 0.23 0.09 0.09 5.00
182 INT204892 Tlr4 Positive_regulation of C1qa 1 0.23 0.09 0.09 5.00
183 INT204904 Tlr4 Positive_regulation of Hexb 1 0.14 0.09 0.09 5.00
184 INT204885 Tlr4 Negative_regulation of Positive_regulation of Cd44 1 0.21 0.09 0.09 5.00
185 INT283427 Lcn2 Positive_regulation of Nt5e 1 0.08 0.21 0.09 5.00
186 INT204884 Tlr4 Negative_regulation of Negative_regulation of Hexb 1 0.13 0.09 0.09 5.00
187 INT204902 Negative_regulation of Tlr4 Positive_regulation of Stat1 1 0.23 0.09 0.09 5.00
188 INT204879 Tlr4 Positive_regulation of Stat1 1 0.25 0.09 0.09 5.00
189 INT204895 Tlr4 Positive_regulation of Gene_expression of Cp 1 0.38 0.47 0.09 5.00
190 INT204889 Tlr4 Negative_regulation of Cd44 1 0.10 0.09 0.09 5.00
191 INT270201 Binding of CD28 and Cd86 1 0.10 0.58 0.08 5.00
192 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08 5.00
193 INT193691 Positive_regulation of Positive_regulation of Bcr 1 0.01 0.07 0.08 5.00
194 INT348971 Binding of MOG and CARTPT 1 0.06 0.73 0.08 5.00
195 INT193692 IgG2a Positive_regulation of Bcr 1 0.02 0.07 0.08 5.00
196 INT270197 Binding of Apc and Cd86 1 0.02 0.58 0.08 5.00
197 INT193694 IgG2a Positive_regulation of Tlr9 1 0.05 0.07 0.08 5.00
198 INT270202 Binding of CD28 and Cd80 1 0.09 0.58 0.08 5.00
199 INT270198 Binding of Apc and Cd80 1 0.02 0.58 0.08 5.00
200 INT204880 Tlr4 Positive_regulation of Cp 1 0.56 0.63 0.07 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Bacterial Meningitis. They are ordered first by their pain relevance and then by number of times they were reported in Bacterial Meningitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT61255 Negative_regulation of Transcription of Nfkb1 6 0.23 2.79 2.2 100.00
2 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24 100.00
3 INT215107 Gene_expression of Spir1 17 0.50 10.38 0.25 100.00
4 INT20378 Localization of Hand1 53 0.71 41.96 13.31 100.00
5 INT180922 Negative_regulation of Mmp8 4 0.43 8.35 3.72 100.00
6 INT228061 Positive_regulation of Localization of Hand1 8 0.26 6.39 2.06 100.00
7 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 99.98
8 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07 99.98
9 INT247102 Binding of MBL2 16 0.38 14.18 1.54 99.96
10 INT111668 Binding of C3 4 0.36 3.84 0.87 99.88
11 INT123890 Localization of Cxcl2 11 0.67 8.03 3.65 99.84
12 INT123887 Negative_regulation of Localization of Cxcl2 2 0.18 1.57 1.35 99.84
13 INT287436 Positive_regulation of HTs 9 0.60 2.27 1.14 99.84
14 INT142780 Negative_regulation of Positive_regulation of Csf2 3 0.35 1.48 0.6 99.84
15 INT61258 Transcription of Nfkb1 24 0.67 10.89 6.32 99.82
16 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47 99.76
17 INT151029 Positive_regulation of Gene_expression of Lcn2 8 0.68 4.04 2.65 99.76
18 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 99.62
19 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 99.44
20 INT142753 Gene_expression of Lcn2 28 0.76 10.03 3.62 99.44
21 INT68576 Positive_regulation of Positive_regulation of CSF2 8 0.40 8.1 2.83 99.44
22 INT353612 Positive_regulation of Transcription of Muc5ac 1 0.44 0.48 0.08 99.44
23 INT212510 Binding of Apcs 26 0.48 15.2 0.72 99.40
24 INT9945 Negative_regulation of Csf2 35 0.51 17.85 11.22 99.40
25 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 99.36
26 INT147793 Localization of COPD 70 0.64 89.01 7.3 99.36
27 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 99.22
28 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66 99.20
29 INT10885 Negative_regulation of C3 9 0.38 11.86 1.35 99.12
30 INT205510 Binding of ST5 1 0.13 0.95 0 99.12
31 INT79835 Regulation of Il10 28 0.61 21.22 11.29 99.08
32 INT79693 Regulation of Il4 30 0.51 21.96 8.6 99.08
33 INT98225 Regulation of Il5 8 0.45 5.07 2.06 99.08
34 INT298029 Positive_regulation of Regulation of Il4 1 0.15 0.39 0.04 99.08
35 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 99.04
36 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 98.96
37 INT353618 Transcription of Muc5ac 1 0.68 0.48 0.08 98.96
38 INT353610 Regulation of Transcription of Muc5ac 1 0.58 0.48 0.08 98.96
39 INT158998 Negative_regulation of PTPLA 4 0.41 4.33 0 98.88
40 INT107033 Gene_expression of Slc37a4 66 0.62 27.34 12.35 98.80
41 INT69203 Positive_regulation of Ntf3 43 0.66 19.16 16.49 98.76
42 INT37835 Negative_regulation of CPP 61 0.51 31.34 18.57 98.72
43 INT18893 Positive_regulation of CPP 81 0.69 38.03 34.33 98.72
44 INT37834 Negative_regulation of Positive_regulation of CPP 14 0.58 6.22 5.69 98.72
45 INT214 Localization of AVP 370 0.81 208.51 91.09 98.56
46 INT64965 Binding of AGFG1 8 0.10 3.53 0.45 98.52
47 INT184303 Positive_regulation of Bglap 16 0.66 8.66 1.25 98.48
48 INT181362 Negative_regulation of Ccl5 21 0.40 15.63 4.96 98.44
49 INT168418 Positive_regulation of RCT 32 0.55 20.2 4.07 98.36
50 INT125384 Positive_regulation of Pain1 23 0.49 17.1 14.83 98.28
51 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 98.16
52 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 98.08
53 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 98.08
54 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 98.08
55 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 98.08
56 INT55880 Negative_regulation of Gene_expression of CCL2 49 0.59 22.37 18.09 98.08
57 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 97.92
58 INT125383 Positive_regulation of Rpl13a 1 0.00 0.2 0 97.92
59 INT18894 Gene_expression of CPP 44 0.77 23.05 23.05 97.88
60 INT18007 Positive_regulation of C6orf25 23 0.66 14.98 1.95 97.84
61 INT257384 Positive_regulation of Positive_regulation of C6orf25 2 0.14 2.17 0 97.84
62 INT11185 Regulation of Slco1c1 15 0.44 6.88 4.52 97.80
63 INT164189 Gene_expression of TREM1 82 0.62 60.77 5.85 97.74
64 INT224154 Positive_regulation of TREM1 14 0.56 22.65 2.71 97.48
65 INT100051 Binding of MUC5AC 20 0.32 14.21 1.14 97.44
66 INT81796 Binding of AGRP 62 0.36 37.19 5.3 97.44
67 INT278530 Regulation of Positive_regulation of Insr 1 0.01 1.96 0.28 97.26
68 INT91754 Gene_expression of Cp 42 0.77 21.97 5.38 97.12
69 INT261203 Binding of HTs 5 0.32 3.01 0.71 97.00
70 INT47909 Binding of CPP 32 0.48 24.9 13.79 97.00
71 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 97.00
72 INT89217 Negative_regulation of ADAMTS13 8 0.50 12.32 0.51 96.84
73 INT16236 Negative_regulation of CFH 31 0.57 19.59 3.36 96.84
74 INT136097 Negative_regulation of CD46 1 0.13 1.91 0.09 96.84
75 INT123705 Gene_expression of SMARCB1 40 0.73 19.47 2.2 96.64
76 INT102548 Negative_regulation of Ccr2 14 0.59 19.84 7.22 96.64
77 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 96.60
78 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 96.32
79 INT72127 Protein_catabolism of MMRN1 68 0.52 56 14.13 96.28
80 INT353615 Positive_regulation of Positive_regulation of Muc5ac 1 0.44 0.48 0.07 96.28
81 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 95.96
82 INT148212 Negative_regulation of Gene_expression of C3 2 0.43 5.47 1.24 95.92
83 INT1120 Gene_expression of C3 33 0.67 22.86 7.56 95.92
84 INT70970 Binding of COPD 144 0.42 180.34 18.29 95.88
85 INT4489 Positive_regulation of Muc5ac 5 0.66 5.39 1.91 95.88
86 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 95.52
87 INT6481 Binding of TNF 624 0.48 510.2 214.82 95.40
88 INT202349 Positive_regulation of Map2k3 3 0.52 1.26 0.36 95.40
89 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 95.20
90 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 95.04
91 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 94.84
92 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 94.76
93 INT100242 Gene_expression of MBLAC2 1 0.75 0.94 0.08 94.72
94 INT69877 Positive_regulation of Positive_regulation of Nfkb1 53 0.68 31.44 20.7 94.68
95 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 94.56
96 INT9660 Regulation of TNF 363 0.62 312.94 139.99 94.48
97 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 94.40
98 INT235503 Phosphorylation of Olr1 1 0.04 0.45 0.07 94.40
99 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 94.32
100 INT337577 Positive_regulation of Phosphorylation of TREM1 1 0.37 1.79 0.21 94.16
101 INT264849 Gene_expression of HTs 9 0.68 2.23 0.84 94.08
102 INT49802 Localization of MUC1 75 0.81 44.74 8.87 94.00
103 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 93.88
104 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 93.88
105 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31 93.88
106 INT196261 Negative_regulation of Positive_regulation of SGCA 1 0.01 0.55 0 93.80
107 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 93.64
108 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 93.56
109 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 93.48
110 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 92.96
111 INT337579 Phosphorylation of TREM1 1 0.51 1.71 0.21 92.96
112 INT57691 Regulation of Gene_expression of Ptger2 23 0.40 17.08 4.61 92.92
113 INT19759 Gene_expression of LBP 77 0.77 56.44 33.23 92.88
114 INT160599 Regulation of Gene_expression of LBP 2 0.44 1.23 0.92 92.88
115 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16 92.84
116 INT16257 Regulation of Gene_expression of Ntf3 8 0.43 4 5.63 92.84
117 INT122368 Regulation of Regulation of Ngf 1 0.27 1.37 1.27 92.84
118 INT155052 Regulation of Gene_expression of Csf2 6 0.37 7.75 0.8 92.84
119 INT86559 Negative_regulation of KITLG 8 0.41 3.54 0.99 92.72
120 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 92.72
121 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 92.52
122 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 92.36
123 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 92.36
124 INT12001 Regulation of Ngf 97 0.62 54.64 76.25 92.36
125 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03 92.36
126 INT16256 Regulation of Ntf3 15 0.49 9.75 13.07 92.36
127 INT269960 Negative_regulation of Hoxb8 2 0.38 1.03 0.24 92.16
128 INT149985 Gene_expression of Tlr9 32 0.75 29.83 11.86 92.04
129 INT149986 Positive_regulation of Gene_expression of Tlr9 5 0.67 8.18 4.15 92.04
130 INT51685 Gene_expression of LTB4R 87 0.58 68.69 31.72 92.00
131 INT183086 Regulation of HTL 3 0.24 1.46 0.05 92.00
132 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 91.84
133 INT96693 Binding of COL2A1 45 0.46 37.11 2.61 91.76
134 INT67389 Positive_regulation of SGCA 7 0.45 2.92 0.69 91.76
135 INT35242 Negative_regulation of MBL2 17 0.48 12.53 1.73 91.60
136 INT4297 Negative_regulation of CFP 21 0.42 12.7 10.29 91.60
137 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 91.56
138 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67 91.56
139 INT132997 Localization of Mmp9 59 0.80 45.9 17.61 91.44
140 INT132994 Positive_regulation of Localization of Mmp9 12 0.42 9.4 3.75 91.44
141 INT108780 Positive_regulation of Gene_expression of Ptger2 94 0.49 59.71 16.22 91.08
142 INT191017 Localization of Cd79a 28 0.56 13.94 2.55 90.92
143 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 90.88
144 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 90.88
145 INT15173 Positive_regulation of Gene_expression of Itgam 59 0.49 21.89 5.43 90.88
146 INT47712 Positive_regulation of App 135 0.69 101.38 28.94 90.80
147 INT110025 Positive_regulation of Positive_regulation of Mapk14 39 0.63 20.67 12.71 90.60
148 INT166311 Positive_regulation of Gene_expression of LBP 7 0.49 4.15 1.81 90.60
149 INT140680 Negative_regulation of DYNLT1 1 0.29 0.93 0.18 90.56
150 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34 90.48
151 INT10166 Localization of Tnf 237 0.81 153.95 88.64 90.48
152 INT81280 Binding of Atp9a 20 0.47 11.14 3.24 90.40
153 INT151036 Positive_regulation of Lcn2 13 0.49 8.57 2 90.36
154 INT158064 Negative_regulation of Gene_expression of LBP 1 0.41 1.54 0.97 90.32
155 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 90.28
156 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 90.24
157 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 90.08
158 INT1261 Localization of Adh1 63 0.81 19.36 16.09 90.08
159 INT2405 Negative_regulation of SGCA 15 0.57 6.04 2.45 89.80
160 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 89.72
161 INT92129 Positive_regulation of Gene_expression of F3 13 0.08 12.13 2.02 89.44
162 INT152552 Gene_expression of Muc5ac 24 0.73 19.44 4 89.32
163 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 89.08
164 INT18677 Gene_expression of F3 50 0.65 30.86 5.86 89.08
165 INT76884 Positive_regulation of Cp 22 0.69 12.84 4.6 88.92
166 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 88.88
167 INT110599 Gene_expression of Bglap 49 0.74 41.23 6.97 88.88
168 INT224151 Positive_regulation of Gene_expression of TREM1 14 0.52 13.04 1.36 88.88
169 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 88.60
170 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 88.60
171 INT75832 Positive_regulation of Positive_regulation of IL8 30 0.70 20.77 6.05 88.60
172 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 88.56
173 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26 88.56
174 INT310969 Positive_regulation of LPP 1 0.30 2.32 0.03 88.52
175 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 88.48
176 INT286893 Positive_regulation of Localization of Spir1 1 0.06 0.56 0 88.48
177 INT286894 Localization of Spir1 1 0.10 1.1 0 88.00
178 INT4560 Protein_catabolism of PLG 18 0.96 11.64 2.32 87.96
179 INT192591 Protein_catabolism of RENBP 1 0.02 0.94 0.12 87.96
180 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 87.84
181 INT105162 Gene_expression of Ad 47 0.12 46.53 1.83 87.76
182 INT26073 Gene_expression of Scd1 17 0.70 9.17 0.47 87.76
183 INT546 Binding of ALB 311 0.48 85.98 60.14 87.64
184 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5 87.48
185 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31 87.48
186 INT61252 Negative_regulation of Gene_expression of Itgam 38 0.54 16.48 5.01 87.32
187 INT35271 Negative_regulation of Apcs 12 0.59 8.05 1.36 87.28
188 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 87.16
189 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 87.16
190 INT150540 Binding of TLR2 50 0.45 35.86 10.43 87.12
191 INT94117 Regulation of Gene_expression of Itgam 13 0.36 5.9 1.87 87.12
192 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 87.04
193 INT23351 Positive_regulation of CFI 4 0.29 1.82 0.21 87.00
194 INT174423 Gene_expression of Smcp 39 0.48 29.45 6.06 86.80
195 INT96068 Positive_regulation of Timp1 30 0.58 23.94 8.17 86.56
196 INT8540 Gene_expression of Serpina1a 5 0.66 3.99 0.34 86.56
197 INT46420 Positive_regulation of Gene_expression of Serpina1a 1 0.49 1.17 0.09 86.56
198 INT56100 Negative_regulation of Gene_expression of Ighm 5 0.48 2.07 1.72 86.48
199 INT23344 Gene_expression of Alox5 60 0.75 28.2 13.82 86.36
200 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16 86.32
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