D:Bacterial Respiratory Disease

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Disease Term
Synonyms Actinobacillus, Antibacterial, Antibacterials, ANTIMICROBIALS, BORDETELLA, Haemophilus, HEMOPHILUS, Infectious Respiratory Disease, Infectious Respiratory Diseases, Micro Organism, Micro Organisms
Documents 1944
Hot Single Events 200
Hot Interactions 24

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Bacterial Respiratory Disease. They are ordered first by their relevance to Bacterial Respiratory Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT333560 NOS3 Regulation of HCK 1 0.01 0.2 0 100.00
2 INT147112 LYZ Regulation of Binding of LTF 1 0.14 1.02 0.07 100.00
3 INT283434 Lcn2 Positive_regulation of Localization of IL8 1 0.07 1.33 0.51 98.76
4 INT323386 Negative_regulation of Binding of Lta and Coq10a 1 0.10 0.57 0 97.84
5 INT323385 Binding of Lta and Coq10a 1 0.09 0.56 0 96.68
6 INT175325 Binding of TLR2 and Tlr6 1 0.00 0.39 0.09 94.76
7 INT175327 Binding of TLR2 and Tlr1 1 0.00 0.39 0.09 94.76
8 INT355704 Binding of Cia1 and Aia1 1 0.00 1.85 0.77 90.44
9 INT307018 MT1JP Positive_regulation of Gene_expression of CD69 1 0.05 0.83 0.29 88.92
10 INT307009 MT1JP Positive_regulation of Gene_expression of LAMP1 1 0.03 0.58 0.26 88.92
11 INT349915 Gopc Regulation of Gene_expression of Muc2 1 0.17 0.17 0 86.48
12 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89 86.24
13 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79 86.24
14 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76 85.84
15 INT329830 Tlr4 Positive_regulation of Unk 1 0.16 0.83 0 85.84
16 INT175320 Tlr4 Positive_regulation of Gene_expression of Mmp9 1 0.01 0.54 0.21 84.24
17 INT213749 NHS Positive_regulation of Localization of CALM1 1 0.28 0.58 0.14 83.32
18 INT324861 Positive_regulation of Binding of Tlr1 and Tlr6 1 0.05 0.79 0.05 82.88
19 INT324867 Positive_regulation of Binding of Tlr6 and Tlr2 1 0.10 0.79 0.05 82.88
20 INT324864 Positive_regulation of Binding of Tlr1 and Tlr2 1 0.10 0.79 0.05 82.88
21 INT153696 Binding of GSTM1 and Gstt1 1 0.06 0.71 0.08 82.48
22 INT324872 Binding of Tlr1 and Tlr6 1 0.04 0.79 0.05 82.48
23 INT287878 Binding of CREB1 and CREBBP 2 0.01 0.16 0.12 81.12
24 INT285423 LBP Positive_regulation of Gene_expression of IRF6 1 0.07 0.19 0.09 80.24
25 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 78.56
26 INT285419 Positive_regulation of Binding of CD14 and TLR4 1 0.32 0.19 0.14 78.56
27 INT347577 Binding of MUC1 and MUC16 1 0.25 0.42 0 78.24
28 INT258289 Hmgb1 Positive_regulation of Tlr2 4 0.48 3.61 0.19 76.88
29 INT324859 Hmgb1 Positive_regulation of ecs 1 0.03 0.74 0.03 76.88
30 INT178968 Slc7a2 Negative_regulation of Glb1 1 0.02 1.77 0.05 76.12
31 INT135180 IL1B Positive_regulation of Gene_expression of TNFSF11 2 0.76 1.73 0.75 74.48
32 INT175324 Hsp90b1 Positive_regulation of TLR2 1 0.00 0.65 0.23 73.44
33 INT175317 Hsp90b1 Positive_regulation of Tlr4 1 0.02 0.66 0.23 73.44
34 INT283427 Lcn2 Positive_regulation of Nt5e 1 0.08 0.21 0.09 73.40
35 INT307014 LBR Positive_regulation of Gene_expression of IL6 1 0.01 0.58 0.32 70.92
36 INT307017 LBR Positive_regulation of Gene_expression of TNF 1 0.02 0.58 0.32 69.04
37 INT285421 Positive_regulation of Binding of TLR4 and LY96 1 0.17 0.18 0.13 68.64
38 INT273495 GBP4 Negative_regulation of IMPDH1 1 0.03 0.2 0 68.24
39 INT220317 Binding of CPB1 and PLEKHM1 1 0.00 0.93 0.26 67.72
40 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 67.68
41 INT175321 IL6 Positive_regulation of Localization of Oxt 1 0.01 0.7 0.25 67.36
42 INT220318 Binding of CPB1 and CCL2 1 0.01 0.46 0.13 67.12
43 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 66.60
44 INT186385 Binding of TNF and Tnfrsf1b 4 0.30 3.24 0.42 66.60
45 INT285605 Binding of ROS1 and Tlr4 1 0.01 1.25 0.16 65.12
46 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15 64.80
47 INT307019 MT1JP Positive_regulation of Gene_expression of IL10 1 0.03 0.58 0.32 63.88
48 INT222295 Binding of CPP and Cebpz 1 0.00 0.73 0.05 63.40
49 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6 62.44
50 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 60.72
51 INT266417 Binding of TGM2 and S100a11 1 0.01 0.86 0.16 60.28
52 INT191948 NFKB1 Regulation of Gene_expression of NOS2 1 0.38 1 0.47 57.80
53 INT191950 NFKB2 Regulation of Gene_expression of NOS2 1 0.08 1 0.47 57.80
54 INT333637 Smpd1 Positive_regulation of IRF3 1 0.09 0.62 0 57.60
55 INT283433 Nt5e Positive_regulation of Localization of IL8 1 0.01 0.21 0.07 57.28
56 INT267799 Binding of RLS and ADHD1 1 0.00 4.84 0.14 57.16
57 INT182367 IgG Regulation of Vim 1 0.00 0.99 0.11 55.44
58 INT354789 Tnc Regulation of HSPG2 1 0.02 1.38 0 55.36
59 INT182368 IgG Regulation of Cast 1 0.01 0.99 0.11 54.64
60 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07 53.56
61 INT349916 Binding of Ctnnd1 and Cdh1 1 0.17 0.47 0.07 53.04
62 INT229820 Fos Positive_regulation of Gene_expression of Ghrl 1 0.02 0.05 0.05 52.68
63 INT324874 Positive_regulation of Tlr2 Positive_regulation of Gene_expression of Mif 1 0.05 0.66 0.15 49.60
64 INT324860 Tlr2 Positive_regulation of Gene_expression of Mif 1 0.05 0.66 0.15 49.12
65 INT336738 S100a8 Regulation of Gene_expression of Ambp 1 0.02 2.15 0.24 45.92
66 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93 44.96
67 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22 41.36
68 INT67633 Binding of DST and Gabrd 1 0.03 0 0.41 40.96
69 INT338432 Il23a Positive_regulation of Gene_expression of IL8 1 0.01 1.63 0.09 39.76
70 INT194618 Il17a Positive_regulation of Gene_expression of IL8 2 0.01 1.94 0.67 38.72
71 INT338433 Il17f Positive_regulation of Gene_expression of IL8 1 0.01 1.62 0.09 38.28
72 INT285604 ROS1 Positive_regulation of Gene_expression of Tlr4 1 0.01 1.14 0.2 37.76
73 INT342512 Hsp90b1 Positive_regulation of Gene_expression of HSP90B1 1 0.24 0.62 0.03 36.80
74 INT283426 Binding of Lcn2 and Nt5e 1 0.08 5.8 1.24 35.48
75 INT285420 IRF6 Regulation of Localization of IL6 1 0.03 0.14 0 35.16
76 INT333635 Positive_regulation of Tlr4 Positive_regulation of Transcription of CREB1 1 0.08 0 0.03 31.52
77 INT333634 Positive_regulation of Tlr4 Positive_regulation of Transcription of FYN 1 0.07 0 0.03 31.52
78 INT333632 Tlr4 Positive_regulation of Transcription of FYN 1 0.07 0 0.03 31.20
79 INT333640 Tlr4 Positive_regulation of Transcription of CREB1 1 0.08 0 0.03 31.20
80 INT333568 FYN Regulation of Transcription of JUN 1 0.01 0 0.03 28.40
81 INT333564 CREB1 Regulation of Transcription of JUN 1 0.02 0 0.03 28.40
82 INT285427 LBP Positive_regulation of Localization of IL8 1 0.10 0.19 0 26.72
83 INT175322 Oxt Positive_regulation of Gene_expression of PTGER2 1 0.00 0.09 0.25 25.92
84 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47 25.48
85 INT226906 Binding of Ido1 and Il6 1 0.07 0.67 0.08 22.80
86 INT266388 S100a6 Negative_regulation of Mapk8 1 0.03 0.49 0.06 22.24
87 INT338426 Binding of Hand1 and Hand2 2 0.06 2 0.46 20.24
88 INT324866 Hmgb1 Positive_regulation of Tlr4 1 0.16 1.29 0.13 18.56
89 INT266412 Binding of S100A12 and Ager 1 0.01 1.03 0.15 16.96
90 INT287699 TNF Regulation of Binding of VEGFA 1 0.02 0.46 0.27 16.00
91 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56 13.76
92 INT226904 Nfkb1 Regulation of Gene_expression of Vcam1 1 0.14 0.27 0.12 9.68
93 INT237325 Il6 Positive_regulation of Gene_expression of Ik 2 0.00 2.09 0.72 8.80
94 INT266384 Binding of Ager and S100a6 1 0.01 1.32 0.11 7.84
95 INT266389 Binding of C2 and S100a6 1 0.04 0.5 0.07 6.64
96 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35 6.04
97 INT285429 Binding of IRF6 and TLR6 1 0.08 0.1 0 6.04
98 INT334532 Sema3a Negative_regulation of Gene_expression of Nrp1 1 0.19 7.58 2 5.00
99 INT266391 Binding of Ager and S100a1 1 0.01 5.63 1.69 5.00
100 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57 5.00
101 INT209409 Binding of CALM1 and NHS 2 0.27 0.58 1.32 5.00
102 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 5.00
103 INT334537 Sema3a Negative_regulation of Gene_expression of Plxna1 1 0.08 3.76 1 5.00
104 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96 5.00
105 INT13193 FPR1 Positive_regulation of ELANE 3 0.44 1.22 0.92 5.00
106 INT334529 Pax3 Positive_regulation of Gene_expression of Ngf 1 0.03 0.31 0.91 5.00
107 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 5.00
108 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88 5.00
109 INT209043 Binding of Fn1 and Slc11a1 3 0.03 1.91 0.78 5.00
110 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76 5.00
111 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 5.00
112 INT171901 Binding of TNF and Il1 2 0.18 1.07 0.7 5.00
113 INT245299 Ccl5 Positive_regulation of Localization of IL8 1 0.11 2.87 0.66 5.00
114 INT25248 GNRH1 Regulation of CGA 4 0.30 1.22 0.62 5.00
115 INT181084 Binding of S100a8 and S100a9 6 0.42 2.91 0.62 5.00
116 INT307016 IGKV1-17 Positive_regulation of Gene_expression of IL6 1 0.00 1.01 0.56 5.00
117 INT191762 FPR1 Positive_regulation of Gene_expression of IGKV1D-39 1 0.01 0.84 0.56 5.00
118 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56 5.00
119 INT334526 Trpv1 Positive_regulation of Gene_expression of Sema3a 1 0.31 0.92 0.55 5.00
120 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55 5.00
121 INT266381 Positive_regulation of Ager Positive_regulation of Nfkb1 1 0.00 0.77 0.55 5.00
122 INT266376 Binding of Ager and Itgam 1 0.00 2.31 0.54 5.00
123 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 5.00
124 INT327999 Binding of FPR2 and FPR3 1 0.02 3.72 0.53 5.00
125 INT191947 NFKB2 Positive_regulation of Gene_expression of NOS2 1 0.08 1.51 0.52 5.00
126 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5 5.00
127 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49 5.00
128 INT175326 SERPINH1 Regulation of Pnlip 1 0.00 0.53 0.49 5.00
129 INT14992 FPR1 Positive_regulation of Localization of MPO 2 0.56 1.1 0.49 5.00
130 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46 5.00
131 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46 5.00
132 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46 5.00
133 INT269061 Binding of Il6 and Il6ra 3 0.04 2.59 0.45 5.00
134 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43 5.00
135 INT230461 Binding of TLR1 and TLR2 3 0.33 2.06 0.43 5.00
136 INT231225 Binding of C1S and SFTPC 1 0.39 1.51 0.43 5.00
137 INT336926 Mir341 Regulation of Tlr4 1 0.02 1.57 0.41 5.00
138 INT259637 Binding of Mmp12 and COPD 2 0.02 1.71 0.4 5.00
139 INT330598 Binding of Il6 and Fig4 1 0.11 1.78 0.4 5.00
140 INT266393 Binding of Ager and Fn1 1 0.00 0.82 0.39 5.00
141 INT266382 Binding of Col4a1 and Fn1 1 0.00 0.82 0.39 5.00
142 INT266397 Binding of Ager and Col4a1 1 0.00 0.81 0.38 5.00
143 INT334533 Binding of Foxq1 and Ngf 1 0.05 0.8 0.38 5.00
144 INT179207 KCNAB2 Regulation of Gene_expression of ATP1A4 1 0.00 1.25 0.37 5.00
145 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37 5.00
146 INT350814 Negative_regulation of TNF Positive_regulation of Gene_expression of Cpox 1 0.06 1.33 0.37 5.00
147 INT350816 TNF Positive_regulation of Gene_expression of Cpox 1 0.05 1.33 0.37 5.00
148 INT285598 Maoa Negative_regulation of Aldh3a1 1 0.01 0.18 0.36 5.00
149 INT174699 Binding of Tlr2 and Tlr3 3 0.14 0.66 0.35 5.00
150 INT78893 TNF Regulation of Gene_expression of ICAM1 1 0.24 0.38 0.35 5.00
151 INT266402 Binding of S100P and Ager 1 0.00 2.25 0.35 5.00
152 INT175319 Negative_regulation of Nos2 Negative_regulation of Positive_regulation of Pnlip 1 0.01 0.83 0.34 5.00
153 INT266383 Binding of Ager and S100b 1 0.01 3.48 0.33 5.00
154 INT298472 LPA Positive_regulation of Gene_expression of CXCL16 1 0.05 0.41 0.32 5.00
155 INT235971 Positive_regulation of Binding of Nqo1 and NMO-IgG 1 0.00 1.86 0.32 5.00
156 INT215395 Csf2 Positive_regulation of Ppara 1 0.12 1.33 0.32 5.00
157 INT307008 MT1JP Positive_regulation of Gene_expression of IL6 1 0.02 0.27 0.32 5.00
158 INT191949 NFKB2 Positive_regulation of NOS2 1 0.05 1.16 0.31 5.00
159 INT266375 S100b Positive_regulation of Ager 1 0.02 1.8 0.31 5.00
160 INT338418 Il13 Positive_regulation of Gene_expression of Il9 1 0.07 1.24 0.3 5.00
161 INT272925 Ccl2 Positive_regulation of Gene_expression of Col7a1 1 0.00 0.72 0.3 5.00
162 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3 5.00
163 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3 5.00
164 INT272932 Binding of Mmp9 and COPD 1 0.01 0.78 0.29 5.00
165 INT235957 Binding of Mog and Bcr 1 0.02 1.13 0.29 5.00
166 INT235962 Binding of Bcr and Trav6-3 1 0.00 1.12 0.29 5.00
167 INT272930 Positive_regulation of Binding of Mmp1a and COPD 1 0.01 0.79 0.29 5.00
168 INT272933 Binding of Mmp1a and COPD 1 0.01 0.78 0.29 5.00
169 INT272929 Positive_regulation of Binding of Mmp9 and COPD 1 0.01 0.79 0.29 5.00
170 INT298501 Paf Regulation of Negative_regulation of Alms1 1 0.00 0.63 0.29 5.00
171 INT272928 Positive_regulation of Binding of Mmp12 and COPD 1 0.01 0.79 0.29 5.00
172 INT235966 Binding of Mog and Trav6-3 1 0.01 1.07 0.29 5.00
173 INT215274 Tlr4 Positive_regulation of Ros1 2 0.02 1.48 0.28 5.00
174 INT193479 TLR2 Regulation of Binding of IRF6 1 0.04 0.75 0.28 5.00
175 INT189200 Binding of CA2 and ITPR3 3 0.03 1.9 0.27 5.00
176 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27 5.00
177 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26 5.00
178 INT242215 Binding of ANG and OLR1 1 0.02 1.63 0.25 5.00
179 INT338424 Gtf3a Positive_regulation of Gene_expression of Ik 1 0.00 0.79 0.25 5.00
180 INT128644 Binding of Icam1 and Selp 2 0.39 0.57 0.25 5.00
181 INT225652 Gene_expression of IL4 Positive_regulation of Positive_regulation of IL12A 1 0.06 1.2 0.25 5.00
182 INT230460 Binding of TLR2 and TLR6 2 0.07 1.9 0.25 5.00
183 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24 5.00
184 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24 5.00
185 INT307011 MT1JP Regulation of IL2 1 0.01 0 0.24 5.00
186 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24 5.00
187 INT226911 Slc11a1 Positive_regulation of Gene_expression of Il6 1 0.09 1.12 0.24 5.00
188 INT266421 Binding of HMGB1 and Il1 1 0.02 0.37 0.24 5.00
189 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24 5.00
190 INT307013 MT1JP Negative_regulation of Binding of ROS1 1 0.02 0.64 0.23 5.00
191 INT234755 IL10 Positive_regulation of IFN1@ 1 0.08 0.68 0.23 5.00
192 INT235967 Binding of Ighm and Nqo1 1 0.00 1.45 0.23 5.00
193 INT215396 Il4 Positive_regulation of Gene_expression of Ppara 1 0.03 0.23 0.23 5.00
194 INT266418 Binding of HMGB1 and Tlr4 1 0.09 0.37 0.23 5.00
195 INT332481 ANXA1 Regulation of SGPP2 1 0.45 1.01 0.22 5.00
196 INT189199 JUN Positive_regulation of KRT16 1 0.31 0.58 0.22 5.00
197 INT334522 Ngf Positive_regulation of Nrp1 1 0.19 0.93 0.22 5.00
198 INT338421 Il2ra Negative_regulation of Gene_expression of Ik 1 0.00 1.27 0.22 5.00
199 INT238802 Binding of Ager and Renbp 6 0.02 6.46 0.22 5.00
200 INT338430 Cd4 Negative_regulation of Gene_expression of Ik 1 0.01 1.27 0.22 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Bacterial Respiratory Disease. They are ordered first by their pain relevance and then by number of times they were reported in Bacterial Respiratory Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT52876 Gene_expression of H3 16 0.77 6.87 1.36 100.00
2 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 100.00
3 INT10885 Negative_regulation of C3 9 0.38 11.86 1.35 100.00
4 INT147113 Binding of LTF 14 0.29 18.24 0.98 100.00
5 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 100.00
6 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42 100.00
7 INT18773 Localization of ALB 117 0.80 69.18 13.8 100.00
8 INT57720 Localization of IGHG3 33 0.74 20.24 6.25 100.00
9 INT56364 Regulation of Gene_expression of ITGAM 19 0.61 9.82 5.09 100.00
10 INT23748 Localization of Ltf 15 0.79 5.43 2.07 100.00
11 INT194168 Protein_catabolism of LTF 3 0.67 2.02 0.38 100.00
12 INT284759 Gene_expression of Osgep 1 0.09 1.56 0.12 100.00
13 INT239411 Localization of APOB 10 0.76 5.71 0.04 100.00
14 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 99.98
15 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 99.84
16 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.84
17 INT36301 Negative_regulation of TOP2A 3 0.57 2.66 0 99.78
18 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.76
19 INT150826 Positive_regulation of Pkd1 9 0.37 3.65 0.35 99.74
20 INT125006 Gene_expression of DEFA5 2 0.05 3.38 0.38 99.72
21 INT152730 Positive_regulation of S100a8 48 0.68 47.67 15.4 99.72
22 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45 99.72
23 INT36133 Binding of pid 22 0.42 31.34 4.1 99.70
24 INT28788 Regulation of LYZ 5 0.42 1.8 1.24 99.58
25 INT38920 Positive_regulation of Positive_regulation of Tbxa2r 1 0.01 0.25 0.13 99.56
26 INT36142 Negative_regulation of Hmgcr 33 0.46 15.91 3.54 99.52
27 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73 99.50
28 INT212593 Negative_regulation of IMPDH1 4 0.10 3.01 0.07 99.46
29 INT273497 Negative_regulation of IMPDH2 1 0.02 0.36 0 99.46
30 INT8775 Binding of IGHE 167 0.48 102.61 23.54 99.44
31 INT114237 Gene_expression of Sgtb 1 0.36 0.53 0.18 99.40
32 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 99.40
33 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 99.36
34 INT38056 Localization of Crp 71 0.78 53.14 17.03 99.36
35 INT48078 Regulation of Gene_expression of Il1b 15 0.62 14.78 9.53 99.36
36 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 99.36
37 INT57691 Regulation of Gene_expression of Ptger2 23 0.40 17.08 4.61 99.36
38 INT296386 Localization of DEFA6 3 0.05 0.88 0 99.36
39 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 99.34
40 INT49802 Localization of MUC1 75 0.81 44.74 8.87 99.34
41 INT59244 Regulation of Pla2g2a 5 0.57 3.02 1.82 99.32
42 INT21938 Positive_regulation of Atp7b 26 0.10 11.33 7.1 99.28
43 INT19107 Positive_regulation of Tbxa2r 23 0.62 12.54 8.44 99.28
44 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89 99.24
45 INT51382 Binding of Tlx2 3 0.37 1.03 0.99 99.24
46 INT114236 Negative_regulation of Sgtb 1 0.23 0.55 0.18 99.20
47 INT195080 Positive_regulation of Tnc 4 0.45 26.67 2.34 99.20
48 INT78141 Localization of Kalrn 2 0.44 0.63 0.03 99.16
49 INT178962 Gene_expression of Oca2 15 0.19 5.15 0.38 99.12
50 INT178961 Negative_regulation of Oca2 3 0.02 1.46 0.15 99.12
51 INT140173 Gene_expression of Po 2 0.34 0.53 0 99.12
52 INT3366 Localization of PLEK 44 0.78 15.83 9.55 99.12
53 INT209356 Regulation of SLC9A6 2 0.39 5.61 0.14 99.12
54 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65 99.04
55 INT32648 Gene_expression of Tyrp1 80 0.66 17.9 16.59 99.04
56 INT62425 Regulation of Gene_expression of Tyrp1 7 0.29 1.44 1.41 99.04
57 INT346930 Binding of Anth 1 0.01 0.57 0 99.04
58 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 99.04
59 INT54662 Positive_regulation of Positive_regulation of Il1 21 0.43 19.33 7.14 99.04
60 INT254742 Gene_expression of Cd24 1 0.11 0.46 0.09 99.00
61 INT254732 Localization of Cd24 1 0.12 0.46 0.09 99.00
62 INT19391 Gene_expression of Nt5e 44 0.72 13.99 5.14 98.92
63 INT49506 Regulation of Ptger2 29 0.44 17.38 6.75 98.92
64 INT33567 Gene_expression of CALM1 139 0.67 48.85 56.14 98.88
65 INT209411 Negative_regulation of Gene_expression of CALM1 10 0.37 2.21 3.11 98.88
66 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42 98.80
67 INT132246 Negative_regulation of S100a8 19 0.43 22 7.25 98.76
68 INT142753 Gene_expression of Lcn2 28 0.76 10.03 3.62 98.76
69 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 98.68
70 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 98.68
71 INT115091 Localization of thd 2 0.04 2.38 0.97 98.64
72 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75 98.60
73 INT51028 Regulation of Il1b 28 0.60 21.15 12.47 98.56
74 INT297033 Localization of ATP6V0A1 2 0.50 1.07 0.04 98.54
75 INT1108 Gene_expression of PPY 58 0.75 36.57 10.76 98.48
76 INT145384 Binding of LTA 10 0.32 4.4 0.66 98.44
77 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 98.42
78 INT4663 Positive_regulation of Ada 17 0.69 9.48 7.93 98.40
79 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 98.32
80 INT77433 Regulation of Gene_expression of Nos2 49 0.62 35.07 16.33 98.32
81 INT92836 Regulation of Transcription of Nos2 3 0.58 1.79 0.85 98.32
82 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 98.32
83 INT70639 Gene_expression of Pcsk2 15 0.77 2.44 1.8 98.24
84 INT90766 Gene_expression of PCS 93 0.77 40.48 14.51 98.24
85 INT177759 Negative_regulation of IFN1@ 51 0.57 31.81 7.76 98.22
86 INT190335 Negative_regulation of Positive_regulation of IFN1@ 16 0.42 4.6 1.29 98.22
87 INT141002 Negative_regulation of Fcer2a 15 0.12 7.17 1.88 98.22
88 INT334519 Positive_regulation of Negative_regulation of Fcer2a 1 0.02 0.65 0.03 98.22
89 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 98.12
90 INT56907 Gene_expression of Pcsk1 26 0.75 7.91 2.49 98.12
91 INT132011 Regulation of Gene_expression of Pcsk1 4 0.44 1.24 0.14 98.12
92 INT100059 Gene_expression of MUC4 30 0.75 31.58 4.95 98.12
93 INT8547 Gene_expression of MUC16 116 0.78 75.97 12.18 98.12
94 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 98.12
95 INT5904 Localization of MPO 62 0.81 36.37 14.64 98.00
96 INT117463 Binding of TOP2B 4 0.46 1.64 0.44 98.00
97 INT262727 Regulation of TOP2B 1 0.26 2.23 0.05 98.00
98 INT12339 Localization of IL8 437 0.81 251.87 117.39 97.96
99 INT39180 Gene_expression of NPL 7 0.38 3.61 2.48 97.96
100 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 97.92
101 INT81280 Binding of Atp9a 20 0.47 11.14 3.24 97.92
102 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 97.90
103 INT50765 Positive_regulation of Fcer2a 23 0.68 10.22 2.92 97.90
104 INT20228 Negative_regulation of Gene_expression of Lta 8 0.22 3.81 1.03 97.84
105 INT170308 Gene_expression of Ido1 159 0.75 69.51 15.98 97.84
106 INT4236 Negative_regulation of GLYAT 9 0.57 4.37 3.74 97.84
107 INT57070 Protein_catabolism of VUR 19 0.99 18.75 0.76 97.84
108 INT217429 Positive_regulation of SLC9A6 22 0.38 42.17 0.67 97.80
109 INT58365 Gene_expression of LTF 51 0.78 44.14 7.25 97.76
110 INT132012 Regulation of Gene_expression of Pcsk2 1 0.45 0.49 0.07 97.72
111 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 97.62
112 INT152060 Gene_expression of VUR 75 0.67 83.83 2.34 97.60
113 INT191739 Positive_regulation of 16S 6 0.49 0.76 0.04 97.60
114 INT17817 Binding of VUR 41 0.48 46.85 0.95 97.60
115 INT263949 Negative_regulation of Protein_catabolism of VUR 1 0.37 1.73 0.07 97.60
116 INT150540 Binding of TLR2 50 0.45 35.86 10.43 97.56
117 INT285447 Binding of TLR6 4 0.36 0.48 0.18 97.56
118 INT230469 Binding of TLR1 6 0.40 1.81 0.38 97.56
119 INT125007 Gene_expression of DEFB1 30 0.60 4.14 1.32 97.56
120 INT161515 Positive_regulation of Gene_expression of Il17a 50 0.64 41.52 13.82 97.56
121 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 97.56
122 INT83953 Gene_expression of Cxcl2 140 0.75 113.07 43.65 97.56
123 INT285489 Positive_regulation of Gene_expression of Il22 9 0.32 10.97 3.63 97.56
124 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.54
125 INT7994 Gene_expression of Lta 113 0.67 69.81 19.59 97.44
126 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 97.36
127 INT148288 Gene_expression of CCL15 9 0.25 6.53 3.41 97.36
128 INT346902 Gene_expression of CCL14 1 0.22 0.41 0.17 97.36
129 INT258473 Binding of TOP2A 3 0.05 1.65 0.05 97.32
130 INT4853 Regulation of Hrh2 42 0.45 22.34 16.65 97.28
131 INT118827 Regulation of TOP2A 4 0.04 1.75 0 97.28
132 INT144945 Negative_regulation of Icam1 27 0.50 26.23 7.08 97.20
133 INT204566 Negative_regulation of Localization of Icam1 2 0.19 2.11 0.3 97.20
134 INT52266 Localization of Pls1 2 0.05 1.09 0.39 97.16
135 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14 96.96
136 INT8541 Gene_expression of Csrp1 42 0.76 23.72 6.9 96.92
137 INT266351 Localization of S100A7 1 0.28 0.84 0.03 96.88
138 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 96.84
139 INT22454 Regulation of Crp 213 0.62 160.67 49.24 96.68
140 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 96.48
141 INT66281 Transcription of Nos2 81 0.71 39.49 20.37 96.48
142 INT157725 Gene_expression of ACLS 2 0.13 2.89 0.17 96.44
143 INT177992 Positive_regulation of SNRNP70 28 0.49 16.14 4.28 96.40
144 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 96.24
145 INT60764 Positive_regulation of PPIG 39 0.67 17.08 13.48 96.24
146 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 96.04
147 INT115528 Binding of Ros1 37 0.41 22.96 5.5 96.04
148 INT191765 Regulation of CALM1 15 0.52 9.52 8.56 96.00
149 INT160564 Gene_expression of Il22 64 0.55 59.29 20.9 95.96
150 INT16722 Negative_regulation of MPO 25 0.59 18.55 6.99 95.96
151 INT5903 Negative_regulation of Localization of MPO 10 0.59 5.71 5.45 95.96
152 INT144946 Localization of Icam1 21 0.75 21.84 5.33 95.96
153 INT27217 Negative_regulation of LYZ 6 0.42 3.1 2.26 95.96
154 INT28787 Negative_regulation of Localization of LYZ 4 0.35 0.88 1.39 95.96
155 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 95.92
156 INT37380 Negative_regulation of Sis 31 0.55 19.89 3.92 95.92
157 INT214808 Gene_expression of Ncapg2 20 0.58 27.52 1.58 95.92
158 INT186268 Positive_regulation of Tdo2 13 0.50 8 1.32 95.88
159 INT332567 Regulation of Cmbl 1 0.08 7.09 0 95.84
160 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 95.72
161 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 95.64
162 INT25726 Positive_regulation of TOP2B 4 0.67 4.1 1.19 95.60
163 INT4342 Localization of ALPP 27 0.69 15.19 5.32 95.56
164 INT243320 Negative_regulation of Cd93 1 0.42 0.15 0.05 95.52
165 INT20389 Localization of LYZ 19 0.79 4.58 6.25 95.44
166 INT144639 Regulation of TPCN1 2 0.32 1.08 0 95.44
167 INT243343 Negative_regulation of CD93 1 0.04 0.15 0.05 95.28
168 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 95.20
169 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25 95.20
170 INT115092 Phosphorylation of Ink76 1 0.00 0.19 0.11 95.20
171 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67 94.96
172 INT167546 Positive_regulation of Gene_expression of ecs 6 0.07 5.78 0.92 94.96
173 INT266354 Gene_expression of S100A7 9 0.58 7.35 0.75 94.92
174 INT182898 Regulation of Gene_expression of IFN1@ 18 0.44 9.49 4.46 94.88
175 INT239025 Regulation of Gene_expression of Il17a 9 0.42 7.18 2.09 94.88
176 INT57339 Negative_regulation of HLA-DRA 17 0.49 7.67 1.96 94.88
177 INT115089 Phosphorylation of Pls1 1 0.00 0.19 0.11 94.84
178 INT10100 Binding of ELANE 22 0.47 15.32 5.19 94.72
179 INT170311 Negative_regulation of Ido1 16 0.48 14.47 4.81 94.72
180 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66 94.60
181 INT23045 Positive_regulation of Hbb 31 0.64 19.35 4.54 94.56
182 INT128300 Binding of RatNP-3b 1 0.02 0.75 0.36 94.56
183 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 94.52
184 INT266369 Gene_expression of S100A7A 1 0.29 4.27 0.26 94.48
185 INT84145 Negative_regulation of YDJC 1 0.03 0.44 0.08 94.48
186 INT126966 Positive_regulation of IL1R1 8 0.67 6.93 2.84 94.38
187 INT17052 Binding of SERPINB2 4 0.43 4.89 1.32 94.36
188 INT54839 Positive_regulation of CD1C 1 0.49 0.82 0.08 94.36
189 INT54838 Localization of CD1C 1 0.68 0.82 0.08 94.36
190 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 94.32
191 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 94.28
192 INT186452 Positive_regulation of SFTPB 7 0.47 6.43 0.03 94.24
193 INT219695 Positive_regulation of Gene_expression of COPD 24 0.40 33.04 3.42 94.24
194 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 94.16
195 INT115090 Phosphorylation of thd 1 0.03 0.19 0.11 94.08
196 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 93.56
197 INT242180 Gene_expression of Gramd4 1 0.07 2 0 93.48
198 INT74423 Localization of IL10 91 0.80 61.6 22.95 93.46
199 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 93.44
200 INT55916 Binding of Ap2s1 4 0.14 6.56 1.27 93.44
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