D:Bacterial Vaginosis

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Disease Term
Synonyms Bacterial Vaginitides, Bacterial Vaginitis, Bacterial Vaginoses, NONSPECIFIC VAGINITIS, Vaginitides Bacterial, VAGINITIS BACTERIAL, VAGINITIS NONSPECIFIC, Vaginoses Bacterial
Documents 90
Hot Single Events 30
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Bacterial Vaginosis. They are ordered first by their relevance to Bacterial Vaginosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65 5.00
2 INT339291 Casp1 Positive_regulation of Il1 2 0.12 1.63 0.8 5.00
3 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76 5.00
4 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62 5.00
5 INT220155 IL1RN Regulation of IL1B 2 0.50 0.93 0.61 5.00
6 INT354820 Creb1 Negative_regulation of Transcription of Cpox 1 0.03 0.59 0.38 5.00
7 INT285598 Maoa Negative_regulation of Aldh3a1 1 0.01 0.18 0.36 5.00
8 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35 5.00
9 INT345421 IFNA1 Positive_regulation of Eif2ak2 2 0.03 1.25 0.3 5.00
10 INT354821 Nos2 Positive_regulation of Eif2ak2 1 0.06 0.64 0.3 5.00
11 INT302467 TIMP1 Positive_regulation of Negative_regulation of COL5A2 1 0.00 1.1 0.29 5.00
12 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26 5.00
13 INT234755 IL10 Positive_regulation of IFN1@ 1 0.08 0.68 0.23 5.00
14 INT308084 Binding of HSPG2 and OXT 1 0.04 0.25 0.23 5.00
15 INT285604 ROS1 Positive_regulation of Gene_expression of Tlr4 1 0.01 1.14 0.2 5.00
16 INT353808 HLA-DMA Regulation of HLA-B 1 0.00 1.72 0.19 5.00
17 INT354819 Binding of Cpox and Ptgs2 1 0.02 0.45 0.16 5.00
18 INT285605 Binding of ROS1 and Tlr4 1 0.01 1.25 0.16 5.00
19 INT273251 Binding of IL6 and IL12A 1 0.00 1.15 0.16 5.00
20 INT209196 IL1B Positive_regulation of Gene_expression of TRPC3 1 0.68 0.23 0.15 5.00
21 INT354823 IFNA1 Positive_regulation of Racgap1 1 0.00 1.4 0.15 5.00
22 INT300570 Binding of IL1RN and SUGT1P2 1 0.01 0.43 0.12 5.00
23 INT209195 IL1B Regulation of Gene_expression of TRPC3 1 0.26 0 0.11 5.00
24 INT285602 Trib3 Regulation of Gene_expression of Nos2 1 0.00 0.48 0.07 5.00
25 INT354822 Negative_regulation of Stat3 Negative_regulation of Positive_regulation of IFNA1 1 0.02 0.85 0.06 5.00
26 INT285603 Akt1 Regulation of Gene_expression of Nos2 1 0.02 0.48 0.04 5.00
27 INT329830 Tlr4 Positive_regulation of Unk 1 0.16 0.83 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Bacterial Vaginosis. They are ordered first by their pain relevance and then by number of times they were reported in Bacterial Vaginosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT353810 Negative_regulation of Nxnl1 1 0.01 1.58 0.12 99.98
2 INT133858 Negative_regulation of BCS1L 13 0.51 8.65 0.2 99.70
3 INT45878 Gene_expression of NEU1 14 0.65 7.28 0.47 99.40
4 INT36133 Binding of pid 22 0.42 31.34 4.1 99.36
5 INT197024 Binding of STIP1 11 0.35 10.84 0.52 98.98
6 INT58365 Gene_expression of LTF 51 0.78 44.14 7.25 98.68
7 INT3165 Gene_expression of LYZ 25 0.65 16.72 5.16 98.68
8 INT40565 Gene_expression of SLPI 15 0.75 7.25 2.21 98.68
9 INT124322 Negative_regulation of PNLIP 11 0.31 6.53 1.88 97.16
10 INT11831 Positive_regulation of pid 13 0.40 23.37 1.54 96.80
11 INT200443 Positive_regulation of AES 27 0.60 22.46 3.22 96.32
12 INT9660 Regulation of TNF 363 0.62 312.94 139.99 95.12
13 INT178053 Positive_regulation of STIP1 7 0.44 5.09 0.11 94.76
14 INT273472 Regulation of Gene_expression of BCS1L 1 0.32 1.89 0 94.44
15 INT7253 Negative_regulation of Localization of Gast 70 0.59 21.06 20.06 94.04
16 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 93.88
17 INT157846 Gene_expression of BCS1L 13 0.50 15.89 0.83 93.84
18 INT90 Localization of Gast 400 0.81 137.67 113 93.76
19 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 92.72
20 INT353822 Protein_catabolism of CD79A 1 0.17 1.67 0.03 92.72
21 INT144766 Binding of BCS1L 11 0.32 8.2 0.13 90.20
22 INT6484 Binding of IL1B 122 0.47 75.84 35.07 87.04
23 INT4075 Positive_regulation of Gene_expression of Gast 24 0.68 19.99 4.02 86.44
24 INT30 Gene_expression of Gast 158 0.78 99 41.45 85.52
25 INT36947 Gene_expression of PNLIP 13 0.45 11.04 1.23 83.32
26 INT16919 Gene_expression of IL36RN 48 0.48 32.78 13.83 83.12
27 INT78895 Regulation of CCL5 30 0.46 20.45 10.18 82.76
28 INT203646 Gene_expression of STIP1 26 0.63 23.57 1.14 82.40
29 INT38625 Gene_expression of ELL 8 0.58 12.53 1 82.24
30 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 82.12
31 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 79.08
32 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 77.48
33 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 75.28
34 INT21613 Gene_expression of Pla2g1b 25 0.68 9.05 6.39 75.00
35 INT36132 Negative_regulation of pid 12 0.43 15.15 1.73 74.64
36 INT86437 Binding of IL6 154 0.48 121.22 29.3 73.76
37 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 72.96
38 INT228195 Negative_regulation of Gene_expression of Tlr2 14 0.40 12.17 1.74 72.96
39 INT73673 Negative_regulation of Mtap2 9 0.32 8.25 1.4 72.04
40 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 65.68
41 INT56376 Negative_regulation of AMBP 29 0.35 21.49 2.59 65.08
42 INT183681 Positive_regulation of Tlr3 20 0.62 16.25 4.54 61.76
43 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 61.20
44 INT46559 Gene_expression of pid 11 0.58 13.1 1.93 60.64
45 INT211807 Binding of PTBP1 11 0.31 6.09 0.45 59.96
46 INT15144 Protein_catabolism of IL1B 11 0.92 4.67 2.58 58.72
47 INT121788 Localization of BCS1L 11 0.73 10.16 1.14 58.48
48 INT42032 Localization of PNLIP 4 0.14 3.44 0.41 58.16
49 INT83952 Gene_expression of Cxadr 24 0.75 22.38 6.77 56.56
50 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 55.04
51 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 54.56
52 INT80784 Regulation of BCS1L 9 0.39 7.63 1.47 53.84
53 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 49.76
54 INT81485 Negative_regulation of IL1RN 19 0.57 8.3 4.69 48.36
55 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9 47.60
56 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62 47.20
57 INT39358 Regulation of PDXP 3 0.23 2.7 0.63 43.60
58 INT130696 Positive_regulation of Phosphorylation of Gtf3a 2 0.01 1.37 0.91 41.68
59 INT354812 Positive_regulation of Protein_catabolism of Gtf3a 1 0.01 0.56 0.44 41.68
60 INT110445 Phosphorylation of Gtf3a 15 0.09 5.58 3.07 41.20
61 INT98017 Protein_catabolism of Gtf3a 10 0.11 6.16 0.83 40.40
62 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 40.28
63 INT39416 Gene_expression of Cd79a 81 0.64 45.17 6.08 39.96
64 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 39.76
65 INT60252 Binding of HIVEP1 59 0.32 65.12 5.06 37.96
66 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37 35.64
67 INT97648 Binding of PI3 2 0.35 1.04 0.13 34.72
68 INT105149 Gene_expression of PTBP1 10 0.75 12.27 1.09 33.12
69 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 29.56
70 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 28.72
71 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 28.72
72 INT12922 Gene_expression of Atp9a 115 0.75 50.95 17.01 27.92
73 INT6480 Positive_regulation of IL1RN 59 0.69 33.7 16.66 25.04
74 INT273471 Negative_regulation of PTBP1 7 0.34 9.2 1.1 25.04
75 INT6849 Localization of IL1B 229 0.81 112.56 69.63 23.36
76 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35 23.36
77 INT177759 Negative_regulation of IFN1@ 51 0.57 31.81 7.76 23.12
78 INT221508 Phosphorylation of IFN1@ 14 0.79 8.97 0.77 23.12
79 INT87235 Negative_regulation of Il4 54 0.48 31.51 13.15 22.48
80 INT237765 Phosphorylation of Il4 3 0.33 1.28 0.51 22.48
81 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 19.36
82 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 14.08
83 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 13.60
84 INT120515 Gene_expression of Otc 13 0.66 4.33 2.6 12.84
85 INT247099 Positive_regulation of PTBP1 7 0.50 9.21 0.16 12.48
86 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 12.32
87 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 11.96
88 INT96269 Positive_regulation of Mcpt1 71 0.61 52.38 20.4 11.96
89 INT166881 Positive_regulation of Ccr1 31 0.69 18.14 7.9 11.96
90 INT86713 Positive_regulation of Mip 10 0.67 6.44 2.63 11.96
91 INT31 Negative_regulation of Gene_expression of Gast 10 0.42 5.3 3.34 11.04
92 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 6.64
93 INT57645 Gene_expression of GSTK1 54 0.62 21.05 4.2 5.08
94 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
95 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
96 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 5.00
97 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 5.00
98 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
99 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
100 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
101 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
102 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 5.00
103 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 5.00
104 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
105 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 5.00
106 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61 5.00
107 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
108 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 5.00
109 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
110 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 5.00
111 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38 5.00
112 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
113 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
114 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
115 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
116 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
117 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
118 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
119 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
120 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
121 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 5.00
122 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
123 INT1281 Negative_regulation of Maoa 203 0.59 22.47 91.66 5.00
124 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
125 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 5.00
126 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 5.00
127 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 5.00
128 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48 5.00
129 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
130 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
131 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 5.00
132 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
133 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 5.00
134 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 5.00
135 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
136 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
137 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
138 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 5.00
139 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
140 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
141 INT79093 Positive_regulation of Nos1 101 0.70 46.89 59.61 5.00
142 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 5.00
143 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
144 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 5.00
145 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 5.00
146 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 5.00
147 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 5.00
148 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 5.00
149 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71 5.00
150 INT49028 Positive_regulation of Nos1 102 0.70 34.73 51.05 5.00
151 INT19775 Localization of Il1 183 0.78 145.5 50.91 5.00
152 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
153 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 5.00
154 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
155 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 5.00
156 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 5.00
157 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31 5.00
158 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 5.00
159 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 5.00
160 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 5.00
161 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
162 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 5.00
163 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 5.00
164 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
165 INT13354 Transcription of TNF 108 0.72 85.81 42.32 5.00
166 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 5.00
167 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 5.00
168 INT5454 Localization of CRH 124 0.79 79.18 41.53 5.00
169 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
170 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 5.00
171 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
172 INT20210 Localization of Ngf 69 0.79 46.22 38.57 5.00
173 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 5.00
174 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
175 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 5.00
176 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 5.00
177 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
178 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 5.00
179 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 5.00
180 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
181 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 5.00
182 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 5.00
183 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 5.00
184 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
185 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 5.00
186 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 5.00
187 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 5.00
188 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 5.00
189 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 5.00
190 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 5.00
191 INT90792 Localization of Il10 144 0.80 87.88 30.03 5.00
192 INT32165 Binding of CALM1 92 0.48 24.19 29.57 5.00
193 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 5.00
194 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94 5.00
195 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45 5.00
196 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 5.00
197 INT1765 Positive_regulation of Gene_expression of PTGER2 140 0.51 68.68 27 5.00
198 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 5.00
199 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 5.00
200 INT12681 Regulation of Trib3 76 0.53 23.92 26.58 5.00
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