D:Benign Prostatic Hypertrophy

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Disease Term
Synonyms Adenoma Prostatic, ADENOMAS PROSTATIC, Benign Prostate Hyperplasia, Benign Prostate Hypertrophy, Benign Prostatic Hyperplasia, BENIGN PROSTATIC HYPERPLASIAS, BPH, Enlarged Prostate, Hyperplasia Benign Prostatic, Hyperplasia Prostatic, HYPERPLASIAS BENIGN PROSTATIC
Documents 822
Hot Single Events 200
Hot Interactions 11

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Benign Prostatic Hypertrophy. They are ordered first by their relevance to Benign Prostatic Hypertrophy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT278077 Binding of BPHL and AURKC 1 0.16 4.29 0.69 100.00
2 INT18231 Binding of ADRA1D and HP 2 0.14 0.17 0.64 100.00
3 INT18230 Binding of HP and WWOX 1 0.19 0.17 0.13 100.00
4 INT198382 Binding of AR and SRD5A1 2 0.06 0.84 0.17 98.96
5 INT151094 Binding of TRPA1 and TRPM8 1 0.41 0.2 0.1 98.80
6 INT191802 C2orf69 Positive_regulation of Pca 1 0.00 0.86 0 98.08
7 INT315068 Binding of AKT1 and PAR4 1 0.34 4.41 0 96.76
8 INT315066 AKT1 Negative_regulation of PAR4 1 0.39 1.8 0.03 94.56
9 INT126795 RASL12 Positive_regulation of Hal 1 0.01 2.62 0.22 94.24
10 INT126791 RASL12 Positive_regulation of ADRA1D 1 0.24 2.62 0.22 94.24
11 INT315061 PAR4 Positive_regulation of Gene_expression of TNF 1 0.10 1.95 0 91.96
12 INT270330 Binding of HYAL1 and TIMP1 1 0.00 0.2 0.04 79.76
13 INT279420 CPOX Positive_regulation of VEGFC 1 0.04 2.23 0.07 76.36
14 INT279415 Gene_expression of CPOX Positive_regulation of VEGFC 1 0.04 2.23 0.07 76.36
15 INT324593 Binding of PROC and RNASEL 1 0.01 0.91 0.03 62.20
16 INT123660 F2R Positive_regulation of PAR1 2 0.10 1.96 0.22 56.80
17 INT175628 F2R Positive_regulation of F2RL1 1 0.04 1.46 0.03 56.80
18 INT279414 Binding of CPOX and ACTR1B 1 0.04 1.55 0.4 56.40
19 INT339404 Binding of Ar and Tymp 1 0.10 0.06 0 50.00
20 INT339403 Negative_regulation of Binding of Ar and Tymp 1 0.12 0 0 50.00
21 INT339402 Binding of Dlat and Tymp 1 0.19 0 0 50.00
22 INT339405 Negative_regulation of Binding of Dlat and Tymp 1 0.22 0 0 50.00
23 INT339407 Negative_regulation of Binding of AR and Tymp 1 0.04 0 0 50.00
24 INT339406 Binding of AR and Tymp 1 0.03 0.06 0 50.00
25 INT191801 Binding of SELP and CD24 1 0.12 0.67 0 46.00
26 INT175626 TIMP1 Positive_regulation of Gene_expression of MMP9 1 0.03 0.72 0.57 41.84
27 INT175627 TIMP1 Positive_regulation of MMP2 1 0.03 0.71 0.56 41.84
28 INT175623 TIMP1 Positive_regulation of MMP9 1 0.03 0.71 0.56 41.84
29 INT330519 Binding of CD8A and DICER1 1 0.08 0.99 0.38 33.88
30 INT330516 Binding of CD8A and CCR6 1 0.07 0.99 0.38 33.88
31 INT330517 Binding of CD8A and HLA-DRB4 1 0.08 0.99 0.38 33.88
32 INT175625 PAR1 Regulation of Gene_expression of MMP9 1 0.02 1.25 0.05 32.04
33 INT16104 GNRH1 Positive_regulation of Lhb 2 0.03 0.53 0.14 25.00
34 INT16100 Gnrh1 Positive_regulation of Localization of Lhb 1 0.06 0.13 0 25.00
35 INT16103 GNRH1 Positive_regulation of Localization of Gnrh1 1 0.02 0.07 0 25.00
36 INT16101 Gnrh1 Positive_regulation of Lhb 1 0.06 0.12 0 25.00
37 INT341378 Positive_regulation of Ros1 Positive_regulation of Parp1 1 0.01 1.08 0.22 19.84
38 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
39 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99 5.00
40 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
41 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 5.00
42 INT25248 GNRH1 Regulation of CGA 4 0.30 1.22 0.62 5.00
43 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58 5.00
44 INT339532 FGF2 Positive_regulation of YWHAZ 1 0.00 1.26 0.54 5.00
45 INT156517 Binding of CNR1 and FAAH 3 0.38 1.53 0.53 5.00
46 INT328058 IL4 Positive_regulation of FAAH 1 0.29 4.29 0.53 5.00
47 INT330522 Binding of CD8A and TNFSF10 1 0.17 1.24 0.48 5.00
48 INT330515 TNFSF10 Regulation of Gene_expression of CD4 1 0.29 1.24 0.4 5.00
49 INT330518 TNFSF10 Regulation of CD4 1 0.29 1.24 0.4 5.00
50 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
51 INT328064 IL10 Positive_regulation of FAAH 1 0.05 1.48 0.26 5.00
52 INT257577 CALCA Positive_regulation of DMD 1 0.01 0.57 0.26 5.00
53 INT330521 Binding of CD4 and TNFSF10 1 0.20 0.73 0.24 5.00
54 INT257776 Phosphorylation of AR Positive_regulation of Localization of TAB2 1 0.26 0.38 0.24 5.00
55 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23 5.00
56 INT339570 Gene_expression of Positive_regulation of Gene_expression of CYP4A11 1 0.00 0.5 0.23 5.00
57 INT339535 FGF2 Positive_regulation of Gene_expression of CYP4A11 1 0.00 0.55 0.22 5.00
58 INT306178 Rhoa Positive_regulation of Rock2 2 0.40 1.04 0.21 5.00
59 INT328059 IL4 Regulation of FAAH 1 0.25 4.57 0.21 5.00
60 INT330520 Positive_regulation of Binding of CD8A and TNFSF10 1 0.19 0.62 0.21 5.00
61 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
62 INT232005 Binding of Cd36 and Tsp1 2 0.25 1.81 0.16 5.00
63 INT241844 Positive_regulation of GNRH1 Positive_regulation of Localization of PLOD1 1 0.13 0.08 0.15 5.00
64 INT276228 Nrtim1 Positive_regulation of PPARG 1 0.01 2.18 0.14 5.00
65 INT252902 PTTG1 Regulation of MMP2 1 0.01 1.5 0.14 5.00
66 INT178446 Binding of Egfr and ras 1 0.04 0.13 0.13 5.00
67 INT253009 Igf1 Regulation of PTTG1 1 0.03 0.44 0.13 5.00
68 INT178431 Positive_regulation of Binding of Egfr and ras 1 0.05 0.13 0.13 5.00
69 INT253015 Egf Regulation of PTTG1 1 0.02 0.44 0.13 5.00
70 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13 5.00
71 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
72 INT328060 LEP Positive_regulation of FAAH 1 0.06 0.7 0.13 5.00
73 INT182368 IgG Regulation of Cast 1 0.01 0.99 0.11 5.00
74 INT182367 IgG Regulation of Vim 1 0.00 0.99 0.11 5.00
75 INT328063 IL4 Positive_regulation of Gene_expression of CNR1 1 0.14 0.93 0.11 5.00
76 INT289670 NPVF Negative_regulation of Positive_regulation of GNRH1 1 0.34 0.06 0.11 5.00
77 INT328067 IL4 Positive_regulation of BTG2 1 0.03 0.8 0.11 5.00
78 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 5.00
79 INT328062 IL4 Regulation of CNR1 1 0.18 2.53 0.1 5.00
80 INT246478 Binding of SERPINE1 and ANGPTL5 1 0.01 1.32 0.1 5.00
81 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 5.00
82 INT339533 VEGFA Positive_regulation of Gene_expression of CYP2C8 1 0.09 0.57 0.09 5.00
83 INT270777 Binding of DMD and BPs 1 0.01 0.33 0.09 5.00
84 INT279435 Positive_regulation of Binding of LTA4H and Lts1 1 0.00 0.16 0.08 5.00
85 INT178434 Il6 Positive_regulation of Ar 1 0.01 0.93 0.08 5.00
86 INT279419 RARB Regulation of PPARA 1 0.01 0.13 0.08 5.00
87 INT257777 INCENP Positive_regulation of AR 1 0.04 0.49 0.08 5.00
88 INT279416 NR1H4 Regulation of PPARA 1 0.01 0.13 0.08 5.00
89 INT339534 VEGFA Positive_regulation of CYP2C18 1 0.04 0.57 0.08 5.00
90 INT279436 Binding of LTA4H and Lts1 1 0.00 0.16 0.08 5.00
91 INT289671 NPVF Regulation of GNRH1 1 0.40 0.08 0.08 5.00
92 INT351651 Enpep Positive_regulation of Agt 1 0.22 0.93 0.07 5.00
93 INT351655 Avp Positive_regulation of Agt 1 0.11 0.94 0.07 5.00
94 INT279421 Binding of NR1H4 and MLXIPL 1 0.00 0.27 0.07 5.00
95 INT279413 Binding of RARB and MLXIPL 1 0.00 0.27 0.07 5.00
96 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07 5.00
97 INT279417 Binding of PPARA and MLXIPL 3 0.00 0.33 0.07 5.00
98 INT329429 Binding of Col7a1 and Hmgcr 1 0.01 0.28 0.06 5.00
99 INT178438 Mapk8 Positive_regulation of Plau 1 0.06 0.52 0.06 5.00
100 INT258015 Binding of ANGPT2 and REN 1 0.01 0.59 0.05 5.00
101 INT178430 Pawr Positive_regulation of Phosphorylation of Mapk14 1 0.05 0.29 0.05 5.00
102 INT218953 Esyt1 Negative_regulation of Ncor1 1 0.00 0.1 0.05 5.00
103 INT341375 Sod2 Regulation of Bcl2 1 0.08 1.96 0.05 5.00
104 INT178447 Negative_regulation of Pawr Positive_regulation of Phosphorylation of Mapk14 1 0.05 0.29 0.05 5.00
105 INT175631 F2RL1 Positive_regulation of Positive_regulation of MMP1 1 0.08 0.69 0.04 5.00
106 INT258012 ANGPT2 Positive_regulation of Binding of AGTR1 and ANGPT2 1 0.00 0.29 0.04 5.00
107 INT253023 Binding of PTTG1 and Myc 1 0.16 0.22 0.04 5.00
108 INT178443 Negative_regulation of Mapk8 Positive_regulation of Negative_regulation of Mapk14 1 0.13 0.76 0.04 5.00
109 INT178441 Binding of Ar and Sra1 1 0.00 0.45 0.04 5.00
110 INT339569 VEGFA Positive_regulation of Litaf 1 0.18 0.6 0.04 5.00
111 INT178435 Mapk1 Regulation of Phosphorylation of Src 1 0.03 0.49 0.04 5.00
112 INT252897 Binding of PTTG1IP and PTTG1 1 0.04 0.15 0.04 5.00
113 INT348881 Atpif1 Positive_regulation of If3 1 0.01 0.08 0.04 5.00
114 INT252892 PTTG1IP Regulation of PTTG1 1 0.05 0.49 0.04 5.00
115 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04 5.00
116 INT348885 Atpif1 Positive_regulation of EIF5B 1 0.01 0.08 0.04 5.00
117 INT178436 Mapk14 Positive_regulation of Gene_expression of Hist1h1a 1 0.17 0.2 0.04 5.00
118 INT351652 Enpep Positive_regulation of Positive_regulation of Agt 1 0.19 0.05 0.04 5.00
119 INT175629 PAR1 Positive_regulation of Positive_regulation of MMP1 1 0.21 0.69 0.04 5.00
120 INT178439 Binding of Ar and Src 1 0.01 0.44 0.04 5.00
121 INT328057 IL4 Regulation of Binding of FAAH 1 0.19 1.1 0.04 5.00
122 INT253017 PTTG1IP Regulation of Regulation of Fgf2 1 0.03 0.49 0.04 5.00
123 INT178428 Regulation of Il6 Positive_regulation of Ar 1 0.01 0.47 0.04 5.00
124 INT334918 GNRH1 Positive_regulation of Gene_expression of FSHR 2 0.11 1.27 0.03 5.00
125 INT279418 Binding of PPARA and RARB 1 0.01 0.14 0.03 5.00
126 INT328065 IL4 Regulation of Gene_expression of FAAH 1 0.19 0.82 0.03 5.00
127 INT327451 HTN1 Positive_regulation of Adra1a 1 0.00 1.36 0.03 5.00
128 INT351663 Binding of AGT and Agt 1 0.32 0.57 0.03 5.00
129 INT351653 Enpep Positive_regulation of Protein_catabolism of Agt 1 0.22 0.54 0.03 5.00
130 INT270775 PTH Regulation of DMD 1 0.09 0.64 0.03 5.00
131 INT246480 Binding of ALB and SHBG 2 0.14 1.45 0.03 5.00
132 INT328066 FAAH Regulation of IL4 1 0.16 0.97 0.03 5.00
133 INT253010 Binding of PTTG1 and Fgf2 1 0.07 0.51 0.03 5.00
134 INT270776 PTH Regulation of Negative_regulation of DMD 1 0.09 0.3 0.03 5.00
135 INT218964 Dlst Regulation of AR 1 0.01 0 0.03 5.00
136 INT178442 Mapk1 Regulation of Gene_expression of Il6 1 0.03 0.59 0.03 5.00
137 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03 5.00
138 INT351155 AKT1 Positive_regulation of Positive_regulation of FGF2 1 0.03 0.81 0 5.00
139 INT315052 Binding of IL8 and RELA 1 0.07 0.34 0 5.00
140 INT268510 PDCD4 Regulation of MIR21 1 0.01 1.17 0 5.00
141 INT324347 Binding of UMOD and Scr 1 0.20 2.23 0 5.00
142 INT289672 Binding of GNRH1 and INSR 1 0.02 0 0 5.00
143 INT253003 Pttg1 Regulation of Gene_expression of Id3 1 0.08 0.07 0 5.00
144 INT351167 CAV1 Negative_regulation of Ppp2r1a 1 0.08 1.5 0 5.00
145 INT218963 Dlst Negative_regulation of AR 1 0.00 0.1 0 5.00
146 INT253004 Anapc1 Positive_regulation of Binding of Pttg1 1 0.47 0 0 5.00
147 INT324342 UMOD Positive_regulation of Scr 1 0.17 1.29 0 5.00
148 INT151092 BPHL Regulation of Gene_expression of TRPM8 1 0.05 0 0 5.00
149 INT334921 GNRHR Positive_regulation of Gene_expression of CGA 1 0.01 0.53 0 5.00
150 INT315053 Negative_regulation of AKT1 Positive_regulation of Binding of RELA 1 0.10 0.12 0 5.00
151 INT178440 Map2k4 Positive_regulation of Mapk14 1 0.04 0.13 0 5.00
152 INT232006 Binding of Trp53 and Tsp1 1 0.06 0.75 0 5.00
153 INT324312 Binding of GATM and UMOD 1 0.02 1.62 0 5.00
154 INT218952 Dlst Negative_regulation of Igf1 1 0.03 0.1 0 5.00
155 INT268514 MYC Regulation of MIR17HG 1 0.05 0.8 0 5.00
156 INT252910 PTTG1 Negative_regulation of Transcription of SLC5A5 1 0.02 0.36 0 5.00
157 INT268515 MIR221 Positive_regulation of BCOR 1 0.09 1.36 0 5.00
158 INT306114 GOPC Regulation of Gene_expression of FGF7 1 0.05 0.45 0 5.00
159 INT268517 MYC Regulation of CTGF 1 0.03 0.92 0 5.00
160 INT315057 Binding of TOP1 and PAR4 1 0.16 1.23 0 5.00
161 INT324306 Binding of GATM and STC1 1 0.02 1.61 0 5.00
162 INT175624 Gene_expression of CDH2 Positive_regulation of CDH1 1 0.00 1.12 0 5.00
163 INT178448 Mapk1 Regulation of Localization of VEGFA 1 0.01 0.51 0 5.00
164 INT253011 Negative_regulation of Binding of PTTG1 and Zic2 1 0.01 0.41 0 5.00
165 INT252886 PTTG1IP Positive_regulation of Binding of SLC5A5 and USF1 1 0.00 0.22 0 5.00
166 INT268520 MIR19B1 Regulation of CASP8 1 0.14 1 0 5.00
167 INT252887 PTTG1IP Positive_regulation of Binding of SLC5A5 and PAX8 1 0.01 0.22 0 5.00
168 INT351166 Gtf3a Positive_regulation of Gene_expression of CAV1 1 0.01 0.79 0 5.00
169 INT334922 GNRHR Positive_regulation of Gene_expression of PLOD1 1 0.08 0.53 0 5.00
170 INT252898 Binding of SLC5A5 and USF1 1 0.01 0.22 0 5.00
171 INT328061 IL4 Regulation of Gene_expression of CNR1 1 0.18 0.81 0 5.00
172 INT351156 VEGFA Positive_regulation of Gene_expression of CAV1 1 0.07 0.79 0 5.00
173 INT253021 PTTG1 Regulation of Gene_expression of Fgf2 1 0.04 0.35 0 5.00
174 INT252906 Binding of SLC5A5 and PTTG1 1 0.01 0.69 0 5.00
175 INT334919 GNRH1 Positive_regulation of Gene_expression of CGA 1 0.03 0.52 0 5.00
176 INT270780 BPs Positive_regulation of DMD 1 0.02 0 0 5.00
177 INT151093 BCL2L10 Regulation of Gene_expression of TRPM8 1 0.20 0 0 5.00
178 INT315065 IGF1R Regulation of Gene_expression of PAR4 1 0.37 0.53 0 5.00
179 INT324346 Regulation of UMOD Positive_regulation of Scr 1 0.10 1.31 0 5.00
180 INT315069 ITGB4 Regulation of MT1X 1 0.27 0.52 0 5.00
181 INT253007 Igf1 Regulation of Gene_expression of PTTG1 1 0.03 0.46 0 5.00
182 INT252889 Binding of PTTG2 and PTTG3P 1 0.06 0.08 0 5.00
183 INT218954 Dlst Regulation of Gene_expression of Igf1 1 0.03 0 0 5.00
184 INT268507 MYC Regulation of MYC Regulation of MIR17HG 1 0.01 0.8 0 5.00
185 INT268512 TP53INP1 Regulation of MIR155 1 0.02 0.97 0 5.00
186 INT268513 MIR34A Regulation of Gene_expression of TP53 1 0.00 0.9 0 5.00
187 INT315060 PAR4 Regulation of BCL2 1 0.53 0.48 0 5.00
188 INT257589 Negative_regulation of Pth Positive_regulation of DMD 1 0.01 0 0 5.00
189 INT315049 IGF1R Regulation of MT1X 1 0.29 0.52 0 5.00
190 INT268516 Gene_expression of MIR16-2 Positive_regulation of Gene_expression of BCL2 1 0.00 1.15 0 5.00
191 INT324343 SLC12A1 Regulation of Scr 1 0.00 0.25 0 5.00
192 INT232004 Mapk8 Positive_regulation of Transcription of Fasl 1 0.05 0.65 0 5.00
193 INT218951 Negative_regulation of Dlst Negative_regulation of Igf1 1 0.03 0.1 0 5.00
194 INT253018 Binding of PTTG1 and Zic2 1 0.01 0.76 0 5.00
195 INT268524 MYC Regulation of THBS1 1 0.02 1.85 0 5.00
196 INT178433 Fgf1 Positive_regulation of Mapk14 1 0.02 0.65 0 5.00
197 INT349954 ARMC9 Regulation of GOPC 1 0.00 0 0 5.00
198 INT315064 Binding of RELA and PAR4 1 0.08 0.45 0 5.00
199 INT315073 DROSHA Regulation of PAR4 1 0.36 0.13 0 5.00
200 INT268594 MIR146B Regulation of Mirlet7a-1 1 0.02 0.49 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Benign Prostatic Hypertrophy. They are ordered first by their pain relevance and then by number of times they were reported in Benign Prostatic Hypertrophy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT24149 Gene_expression of BPHL 58 0.59 93.54 2.91 100.00
2 INT175652 Positive_regulation of BPHL 9 0.44 17.98 1.14 100.00
3 INT236877 Negative_regulation of Gene_expression of BPHL 12 0.32 16.43 0.56 100.00
4 INT236867 Gene_expression of AURKC 6 0.55 31.96 1.86 100.00
5 INT168262 Positive_regulation of Gene_expression of BPHL 10 0.24 10.72 0.83 100.00
6 INT103942 Binding of BPHL 11 0.30 14.26 0.53 100.00
7 INT93664 Gene_expression of TIMP2 33 0.67 36.67 7.14 100.00
8 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 100.00
9 INT236868 Negative_regulation of AURKC 3 0.48 12.2 1.46 100.00
10 INT98445 Negative_regulation of BPHL 7 0.32 7.24 1.08 100.00
11 INT118610 Localization of BPHL 6 0.57 6.88 0.33 100.00
12 INT95105 Gene_expression of TGFBR2 15 0.64 16.36 2.74 100.00
13 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96 100.00
14 INT175520 Gene_expression of Igf2 43 0.78 48.93 1.21 100.00
15 INT290110 Gene_expression of Emp3 3 0.52 4.47 0.26 100.00
16 INT236872 Regulation of BPHL 6 0.16 6.52 1.14 100.00
17 INT236864 Regulation of Gene_expression of BPHL 4 0.19 3.87 0.09 100.00
18 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 100.00
19 INT290109 Gene_expression of Sgcd 1 0.19 2.49 0 100.00
20 INT103020 Gene_expression of SGCA 22 0.56 14.29 2.75 100.00
21 INT243032 Gene_expression of Rarb 3 0.42 4.47 0.73 100.00
22 INT77031 Gene_expression of LIPG 4 0.51 4.32 0.26 100.00
23 INT96132 Gene_expression of F10 10 0.58 6.99 1.24 100.00
24 INT236870 Positive_regulation of Gene_expression of AURKC 3 0.41 10.18 0.35 100.00
25 INT155565 Gene_expression of Efemp2 22 0.67 7.24 0.13 100.00
26 INT290108 Gene_expression of Col4a5 1 0.18 2.45 0 100.00
27 INT95694 Gene_expression of Chrnb1 6 0.36 4.27 1.33 100.00
28 INT266841 Gene_expression of Cdh13 9 0.69 2.44 2.49 100.00
29 INT269743 Positive_regulation of Binding of BPHL 1 0.19 2.94 0.13 100.00
30 INT236878 Regulation of Gene_expression of AURKC 3 0.15 2.33 0.09 100.00
31 INT275891 Negative_regulation of Localization of BPHL 1 0.19 0.98 0.05 100.00
32 INT110716 Negative_regulation of Cm3 2 0.26 1.21 0.17 100.00
33 INT275887 Negative_regulation of Gene_expression of Cm3 1 0.03 1.03 0 100.00
34 INT287191 Regulation of Positive_regulation of BPHL 1 0.34 1.18 0.04 100.00
35 INT15900 Gene_expression of PEBP1 5 0.61 2.57 0.44 100.00
36 INT68560 Regulation of Gli3 3 0.18 1.51 0.68 100.00
37 INT275886 Gene_expression of Cm3 25 0.23 4.01 0 99.98
38 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96 99.96
39 INT236869 Negative_regulation of Negative_regulation of SRD5A1 2 0.41 2.68 0 99.96
40 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 99.92
41 INT27260 Gene_expression of DYNLL1 8 0.75 7.72 2.78 99.90
42 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86 99.88
43 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12 99.84
44 INT236865 Positive_regulation of AURKC 3 0.57 18.45 0.54 99.84
45 INT93665 Negative_regulation of Gene_expression of TIMP2 4 0.37 2.47 0.82 99.84
46 INT118609 Positive_regulation of CASP6 1 0.49 1.09 0.26 99.84
47 INT278078 Regulation of Positive_regulation of AURKC 1 0.37 2.03 0 99.82
48 INT236874 Regulation of AURKC 3 0.37 2.83 0.09 99.80
49 INT278079 Positive_regulation of Positive_regulation of PVR 1 0.17 2.24 0.49 99.80
50 INT335 Binding of Adra1a 16 0.36 6.16 6 99.74
51 INT126794 Binding of SRD5A1 2 0.36 3.26 0.22 99.74
52 INT118235 Positive_regulation of Igf2 9 0.70 10.05 0.12 99.72
53 INT108405 Gene_expression of FAAH 48 0.78 28.22 9.97 99.66
54 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61 99.62
55 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24 99.62
56 INT73460 Positive_regulation of Gene_expression of Myc 26 0.67 20.44 2.61 99.62
57 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 99.60
58 INT103842 Gene_expression of Cftr 53 0.78 59.59 21.82 99.60
59 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 99.60
60 INT10754 Positive_regulation of Gene_expression of PCa 18 0.41 21.81 4.17 99.60
61 INT124023 Transcription of Ubc 1 0.69 0.58 0.14 99.60
62 INT70323 Negative_regulation of Gene_expression of CA2 13 0.41 6.55 0.97 99.60
63 INT103841 Negative_regulation of Gene_expression of Cftr 3 0.43 1.93 0.63 99.60
64 INT60136 Localization of CXCL5 2 0.10 0.68 1.48 99.60
65 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 99.56
66 INT290120 Gene_expression of SMOC1 1 0.69 2.8 0 99.56
67 INT25208 Gene_expression of IGF2 43 0.74 30.64 2.31 99.56
68 INT117555 Gene_expression of PCAP 11 0.46 11.57 11.03 99.48
69 INT290121 Negative_regulation of Gene_expression of SMOC1 1 0.38 0.82 0 99.44
70 INT19539 Positive_regulation of Gene_expression of ADRA1D 10 0.67 9.4 2.9 99.38
71 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 99.38
72 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 99.32
73 INT126743 Positive_regulation of Gene_expression of LEP 61 0.66 50.02 11.17 99.32
74 INT191807 Gene_expression of CD24 75 0.78 53.92 3.34 99.28
75 INT191806 Positive_regulation of Gene_expression of CD24 13 0.70 9.94 0.79 99.28
76 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 99.28
77 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54 99.28
78 INT231987 Gene_expression of Tsp1 66 0.67 62.58 1.78 99.20
79 INT231995 Positive_regulation of Gene_expression of Tsp1 15 0.60 15.21 0.18 99.20
80 INT263822 Positive_regulation of Gene_expression of LOX 8 0.50 11 1.06 99.12
81 INT825 Negative_regulation of ADRA1D 54 0.58 20.25 22.78 99.12
82 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04 99.10
83 INT102992 Regulation of Negative_regulation of SRD5A1 4 0.60 3.59 0.29 99.08
84 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 99.04
85 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 99.04
86 INT6628 Transcription of Eef1a1 4 0.16 2.59 1.8 99.04
87 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87 98.96
88 INT252975 Positive_regulation of Gene_expression of PTTG1 36 0.28 31.96 0.74 98.96
89 INT252992 Regulation of Gene_expression of PTTG1 1 0.18 5.07 0.04 98.96
90 INT16393 Gene_expression of Serpinf2 4 0.08 3.39 1.09 98.96
91 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 98.96
92 INT77282 Positive_regulation of Cftr 23 0.69 21.8 9.65 98.96
93 INT65261 Regulation of Col7a1 18 0.55 8.7 1.33 98.96
94 INT175635 Positive_regulation of PCAP 2 0.47 1.71 6.9 98.88
95 INT19177 Negative_regulation of GRHPR 19 0.53 12.65 2.71 98.84
96 INT62957 Positive_regulation of CXCL5 13 0.50 8.53 3.28 98.84
97 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 98.84
98 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 98.80
99 INT4880 Regulation of MME 17 0.61 7.78 8.2 98.80
100 INT129161 Binding of TRPM8 7 0.48 1.32 2.48 98.80
101 INT58449 Binding of Mthfd1 47 0.47 22.02 10.29 98.80
102 INT162444 Positive_regulation of CYP4A11 4 0.43 4.11 0.61 98.76
103 INT90673 Gene_expression of LOX 66 0.65 69.71 12.18 98.74
104 INT50673 Positive_regulation of Gene_expression of CPOX 156 0.54 97.31 37.03 98.72
105 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 98.70
106 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 98.70
107 INT123584 Gene_expression of Trpa1 176 0.78 83 78.65 98.70
108 INT109820 Gene_expression of Trpv4 121 0.78 39.69 33.11 98.70
109 INT118611 Positive_regulation of CASP7 1 0.33 1.08 0.26 98.64
110 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 98.62
111 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 98.62
112 INT83374 Gene_expression of FGF7 83 0.78 44.18 2.6 98.60
113 INT343791 Gene_expression of KIAA1524 1 0.78 24.91 0 98.52
114 INT20612 Positive_regulation of Asap1 36 0.68 24.35 6.06 98.50
115 INT129879 Positive_regulation of Gene_expression of CTSS 3 0.47 3.25 0.7 98.44
116 INT191803 Positive_regulation of CD24 6 0.70 5.49 0.43 98.16
117 INT191810 Positive_regulation of Transcription of CD24 3 0.60 2.88 0.15 98.16
118 INT47764 Binding of Jun 106 0.48 22.62 31.39 98.08
119 INT116265 Binding of Myc 9 0.36 4.28 1.36 98.08
120 INT178534 Positive_regulation of SRD5A1 2 0.44 1.23 0 98.02
121 INT19396 Regulation of Rac1 66 0.53 37.41 30.01 97.96
122 INT10924 Positive_regulation of Sysbp1 25 0.04 11.12 7.35 97.92
123 INT287456 Binding of BCL2L10 9 0.42 4.66 0.19 97.88
124 INT236873 Positive_regulation of Localization of AURKC 1 0.17 1.43 0 97.84
125 INT147870 Binding of TRPA1 11 0.48 3.12 4.77 97.84
126 INT94859 Negative_regulation of Pde5a 67 0.43 33.66 10.28 97.80
127 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 97.80
128 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 97.80
129 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8 97.80
130 INT315130 Phosphorylation of PAR4 1 0.80 1.96 0 97.80
131 INT315104 Negative_regulation of Phosphorylation of PAR4 1 0.42 1.97 0 97.80
132 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 97.74
133 INT168263 Gene_expression of IL23A 57 0.58 47.1 17.67 97.74
134 INT343789 Positive_regulation of Gene_expression of KIAA1524 1 0.70 13.59 0 97.68
135 INT18658 Regulation of Adra1a 34 0.62 5.69 13.78 97.68
136 INT260295 Gene_expression of FGFBP1 2 0.62 2.78 0.06 97.56
137 INT92574 Gene_expression of CXCL5 51 0.78 24.87 11.89 97.44
138 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 97.40
139 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63 97.40
140 INT129877 Gene_expression of CTSS 4 0.75 4.65 0.81 97.40
141 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48 97.38
142 INT236871 Binding of AURKC 2 0.39 8.53 0.83 97.28
143 INT127863 Binding of PAR4 2 0.47 19.9 1.03 97.04
144 INT75496 Positive_regulation of MCF2 7 0.08 3.86 0.38 96.96
145 INT191804 Transcription of CD24 10 0.72 12.43 1.25 96.92
146 INT14182 Gene_expression of CPB1 26 0.67 10.06 1.9 96.92
147 INT14186 Positive_regulation of Gene_expression of CPB1 2 0.39 3.46 0.42 96.92
148 INT105086 Positive_regulation of CYCS 9 0.49 5.82 1.45 96.88
149 INT15969 Negative_regulation of Ar 11 0.43 2.77 1.59 96.84
150 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61 96.80
151 INT118791 Binding of AKT1 32 0.48 15.51 2.25 96.76
152 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 96.68
153 INT52980 Positive_regulation of Dlat 20 0.37 5.14 4.06 96.68
154 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 96.68
155 INT236876 Negative_regulation of Localization of SRD5A1 1 0.41 0.81 0.06 96.64
156 INT14184 Positive_regulation of CPB1 23 0.55 14.38 1.73 96.64
157 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 96.52
158 INT236866 Localization of AURKC 2 0.61 2.22 0 96.46
159 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82 96.42
160 INT102071 Negative_regulation of Gene_expression of Myc 8 0.57 3.5 0.22 96.42
161 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 96.28
162 INT236875 Localization of SRD5A1 2 0.73 0.8 0.11 96.20
163 INT7523 Regulation of ADRA1D 42 0.45 11.63 14.52 96.00
164 INT175637 Positive_regulation of Gene_expression of PCAP 2 0.34 1.73 2.47 96.00
165 INT95328 Gene_expression of Gstp1 11 0.61 8.59 0.48 96.00
166 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53 95.90
167 INT63270 Gene_expression of Ncor1 7 0.56 0.65 0.15 95.88
168 INT109110 Positive_regulation of Pde5a 29 0.63 11.16 16.65 95.80
169 INT29394 Gene_expression of Adra1a 9 0.77 3.62 3.91 95.80
170 INT191811 Regulation of CD24 7 0.45 6 0.72 95.76
171 INT191809 Regulation of Gene_expression of CD24 5 0.45 3.04 0.31 95.76
172 INT24662 Gene_expression of F2RL3 4 0.55 3.01 0.71 95.66
173 INT121126 Positive_regulation of RNF34 9 0.04 6.83 2.05 95.52
174 INT110579 Negative_regulation of Gene_expression of MME 15 0.58 12.8 1.81 95.48
175 INT6521 Negative_regulation of Gene_expression of ADRA1D 4 0.57 3.19 2.14 95.40
176 INT198387 Regulation of SRD5A1 2 0.60 1.29 1.26 95.32
177 INT44080 Positive_regulation of HBA1 7 0.25 2.23 0.6 95.32
178 INT275892 Positive_regulation of Gene_expression of HBA1 7 0.67 2.4 0.24 95.32
179 INT90377 Gene_expression of HBA1 26 0.75 7.34 1.51 95.32
180 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59 95.12
181 INT38625 Gene_expression of ELL 8 0.58 12.53 1 95.08
182 INT24328 Gene_expression of Egf 97 0.75 59.65 9.42 94.92
183 INT1168 Binding of PROC 62 0.38 44.15 9.04 94.88
184 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 94.80
185 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 94.80
186 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 94.72
187 INT7113 Negative_regulation of Localization of CGA 71 0.51 17.7 23.42 94.60
188 INT1793 Localization of CGA 379 0.81 67.38 114.69 94.60
189 INT162 Regulation of Prl 794 0.62 165.01 322.24 94.56
190 INT101592 Gene_expression of TRPM8 82 0.78 70.61 22.89 94.40
191 INT114751 Gene_expression of Mapk1 137 0.76 60.14 39.98 94.40
192 INT102825 Regulation of Timp1 10 0.38 5.49 1.79 94.40
193 INT90942 Regulation of P2rx1 31 0.61 16.61 13.69 94.24
194 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 94.16
195 INT130719 Positive_regulation of Gene_expression of OR51E1 1 0.70 2.28 0.37 94.12
196 INT155827 Gene_expression of Dre 2 0.50 1.46 0.05 94.12
197 INT315310 Gene_expression of CHIA 1 0.12 4.45 0.33 94.12
198 INT231984 Negative_regulation of Tsp1 5 0.51 6.01 0.28 94.12
199 INT118270 Regulation of P2RY2 16 0.45 7.02 3.45 94.04
200 INT151095 Gene_expression of ATP6V0A1 13 0.48 4.4 1.37 94.00
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