D:Bile Duct Neoplasms

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pChart

Disease Term
Synonyms Bile Duct Cancer, Bile Duct Cancers, Bile Duct Neoplasm, Cancer Bile Duct, CANCER OF BILE DUCT, Cancer Of The Bile Duct, Cancers Bile Duct, Neoplasm Bile Duct, NEOPLASMS BILE DUCT
Documents 99
Hot Single Events 23
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Bile Duct Neoplasms. They are ordered first by their relevance to Bile Duct Neoplasms and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT342252 Binding of Ercc1 and Tymp 1 0.29 1.24 0 44.80
2 INT346455 IFNA1 Regulation of HCC 1 0.02 1.64 0.23 5.00
3 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21 5.00
4 INT346459 Binding of RNASE1 and ROS1 1 0.06 1.42 0.18 5.00
5 INT346451 Positive_regulation of Binding of IFNA1 and DDX58 1 0.01 0.54 0.15 5.00
6 INT346450 Binding of IFNA1 and DDX58 1 0.01 0.54 0.15 5.00
7 INT329796 TICAM1 Positive_regulation of IFNA1 2 0.02 0.89 0.15 5.00
8 INT346500 TLR3 Positive_regulation of Nfkb1 1 0.01 0.49 0.13 5.00
9 INT346501 MYD88 Positive_regulation of Nfkb1 1 0.01 0.5 0.13 5.00
10 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08 5.00
11 INT346499 Mal Positive_regulation of TICAM1 1 0.06 0.66 0.07 5.00
12 INT346452 TLR3 Positive_regulation of TBK1 1 0.03 0.45 0.06 5.00
13 INT346456 TLR3 Positive_regulation of IKBKE 1 0.02 0.45 0.06 5.00
14 INT346449 TICAM1 Positive_regulation of TBK1 1 0.01 0.45 0.06 5.00
15 INT346454 TICAM1 Positive_regulation of IKBKE 1 0.01 0.45 0.06 5.00
16 INT346457 IRF3 Positive_regulation of IFNA1 1 0.03 0.56 0.05 5.00
17 INT346453 Binding of DDX58 and IFIH1 1 0.00 1.04 0.03 5.00
18 INT342251 Binding of Trp53 and Tymp 1 0.21 1.01 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Bile Duct Neoplasms. They are ordered first by their pain relevance and then by number of times they were reported in Bile Duct Neoplasms. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT118791 Binding of AKT1 32 0.48 15.51 2.25 100.00
2 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 99.84
3 INT114826 Gene_expression of Tymp 40 0.58 22.97 3.71 99.46
4 INT121307 Gene_expression of Ercc1 4 0.73 12.69 1.37 99.46
5 INT118792 Regulation of Positive_regulation of AKT1 8 0.61 3.73 1.15 99.12
6 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34 98.68
7 INT112867 Positive_regulation of Gene_expression of Ccnd1 15 0.56 13.22 1.77 98.68
8 INT105336 Regulation of AKT1 52 0.56 32.53 4.89 98.28
9 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 98.24
10 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 96.36
11 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21 96.36
12 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 95.52
13 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04 95.52
14 INT290303 Localization of HPCAL1 1 0.04 1.2 0.52 94.16
15 INT102985 Binding of AFF1 1 0.02 1.18 0.39 91.92
16 INT342248 Gene_expression of Nbn 1 0.13 3.73 0.08 91.80
17 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32 88.48
18 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 88.28
19 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 87.44
20 INT144487 Binding of FBRS 2 0.18 0.93 0.32 82.96
21 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25 82.32
22 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 81.24
23 INT11824 Negative_regulation of GGT1 3 0.57 1.39 0.53 81.24
24 INT190042 Gene_expression of Bcl2a1b 7 0.05 5.74 0.33 79.52
25 INT121310 Positive_regulation of Ercc1 2 0.45 1.78 0.42 78.40
26 INT121311 Positive_regulation of Gene_expression of Ercc1 3 0.62 1.23 0.21 78.40
27 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41 76.60
28 INT184473 Regulation of Gene_expression of Ccnd1 5 0.40 2.73 0.1 76.60
29 INT191807 Gene_expression of CD24 75 0.78 53.92 3.34 73.84
30 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 72.48
31 INT15888 Positive_regulation of Nbr1 42 0.69 35.76 10.48 72.32
32 INT91210 Negative_regulation of Mrgpre 4 0.41 2.76 0.52 69.40
33 INT290297 Binding of Cq2 1 0.08 1.16 0.03 65.00
34 INT290298 Positive_regulation of Binding of Cq2 1 0.11 1.16 0.03 65.00
35 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32 64.72
36 INT32694 Gene_expression of MUCL1 3 0.06 3.18 0.16 64.64
37 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 58.64
38 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64 57.56
39 INT57338 Gene_expression of ITGAX 31 0.75 24.62 4.39 56.96
40 INT1925 Gene_expression of PLAT 47 0.75 34.76 7.88 54.60
41 INT17846 Binding of Ptgs2 8 0.32 4.66 2.48 51.44
42 INT182313 Regulation of Gene_expression of Birc5 18 0.60 15.34 0.96 49.72
43 INT173634 Positive_regulation of Positive_regulation of CDCP1 3 0.01 2.6 0.07 48.80
44 INT24443 Gene_expression of PSMD2 20 0.54 7.29 2.77 47.96
45 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 47.92
46 INT86729 Positive_regulation of CDCP1 37 0.07 18.74 10.76 47.92
47 INT331941 Binding of Tymp 7 0.27 4.57 0.37 44.80
48 INT342249 Binding of Ercc1 1 0.33 2.69 0 44.52
49 INT78955 Regulation of Gene_expression of Ptgs2 12 0.62 7.22 6.02 44.08
50 INT108327 Negative_regulation of Gene_expression of Ccnd1 18 0.38 14.36 1.31 43.52
51 INT258009 Positive_regulation of DCR 2 0.34 1.05 0 43.08
52 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8 42.64
53 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6 41.36
54 INT79140 Binding of HCC 36 0.31 46.96 1.87 41.04
55 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 40.40
56 INT114827 Positive_regulation of Gene_expression of Tymp 13 0.45 5.69 1.11 36.24
57 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 26.00
58 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71 25.44
59 INT21487 Negative_regulation of HCC 18 0.49 29.81 1.88 8.00
60 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
61 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
62 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
63 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
64 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
65 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
66 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
67 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
68 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 5.00
69 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 5.00
70 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
71 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
72 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 5.00
73 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
74 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 5.00
75 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11 5.00
76 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 5.00
77 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
78 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 5.00
79 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
80 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
81 INT14700 Regulation of IFNA1 111 0.45 66.16 21.52 5.00
82 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 5.00
83 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
84 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 5.00
85 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 5.00
86 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 5.00
87 INT34057 Negative_regulation of Gene_expression of IFNA1 65 0.58 43.46 17.25 5.00
88 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 5.00
89 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 5.00
90 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
91 INT80756 Gene_expression of CD86 77 0.77 46.68 11.36 5.00
92 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89 5.00
93 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
94 INT95565 Positive_regulation of IL12A 47 0.56 33.96 10.16 5.00
95 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69 5.00
96 INT107307 Transcription of IFNA1 30 0.52 18.16 9.61 5.00
97 INT3287 Gene_expression of Gpt 50 0.75 23.69 8.57 5.00
98 INT28671 Positive_regulation of Gene_expression of HLA-E 43 0.67 22.85 8.39 5.00
99 INT93914 Gene_expression of CD80 70 0.75 36.35 7.74 5.00
100 INT8669 Positive_regulation of Afp 66 0.70 58.21 7.67 5.00
101 INT57256 Gene_expression of HLA-DQA2 52 0.55 23.87 6.27 5.00
102 INT122653 Positive_regulation of Gene_expression of CD4 48 0.68 22.5 5.96 5.00
103 INT139329 Phosphorylation of IFNA1 24 0.79 16.19 5.95 5.00
104 INT26069 Positive_regulation of Positive_regulation of IFNA1 26 0.50 16.61 4.76 5.00
105 INT14470 Gene_expression of HCC 83 0.67 110.55 4.61 5.00
106 INT745 Gene_expression of Afp 65 0.78 52.89 4.24 5.00
107 INT70895 Localization of PDGFB 20 0.52 8.98 3.4 5.00
108 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54 5.00
109 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3 5.00
110 INT101572 Negative_regulation of Gene_expression of PCNA 24 0.53 13.87 2.21 5.00
111 INT83896 Gene_expression of CD1A 19 0.68 15.58 2.1 5.00
112 INT58691 Positive_regulation of Gene_expression of CD8A 26 0.50 15.19 1.97 5.00
113 INT18007 Positive_regulation of C6orf25 23 0.66 14.98 1.95 5.00
114 INT1554 Positive_regulation of RNASE1 10 0.67 9.44 1.78 5.00
115 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68 5.00
116 INT122888 Positive_regulation of Transcription of IFNA1 5 0.45 3.51 1.59 5.00
117 INT172953 Binding of Trp53 33 0.37 20.76 1.41 5.00
118 INT101555 Positive_regulation of Nt5e 5 0.45 2.91 1.4 5.00
119 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4 5.00
120 INT60741 Regulation of Positive_regulation of IFNA1 9 0.16 6.98 1.24 5.00
121 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21 5.00
122 INT74297 Gene_expression of Nt5e 3 0.75 0.4 1.14 5.00
123 INT19044 Positive_regulation of GGT5 10 0.65 7.7 1.11 5.00
124 INT188398 Positive_regulation of IL15 8 0.19 4.64 1.06 5.00
125 INT85831 Positive_regulation of CA9 5 0.60 8.29 1.02 5.00
126 INT139852 Regulation of HCC 14 0.39 14.54 0.97 5.00
127 INT191806 Positive_regulation of Gene_expression of CD24 13 0.70 9.94 0.79 5.00
128 INT186804 Binding of TLR3 14 0.45 8.41 0.79 5.00
129 INT191811 Regulation of CD24 7 0.45 6 0.72 5.00
130 INT188775 Binding of IFIH1 11 0.16 12.4 0.61 5.00
131 INT87458 Binding of CD81 4 0.18 6.02 0.59 5.00
132 INT173801 Gene_expression of Ik 11 0.36 1.31 0.51 5.00
133 INT191803 Positive_regulation of CD24 6 0.70 5.49 0.43 5.00
134 INT346479 Positive_regulation of DDX58 1 0.06 5.3 0.42 5.00
135 INT188776 Positive_regulation of IFIH1 10 0.23 9.93 0.35 5.00
136 INT191805 Negative_regulation of CD24 4 0.58 0.61 0.32 5.00
137 INT191809 Regulation of Gene_expression of CD24 5 0.45 3.04 0.31 5.00
138 INT84946 Gene_expression of GGT5 5 0.06 2.31 0.31 5.00
139 INT346492 Protein_catabolism of MAVS 1 0.06 1.74 0.31 5.00
140 INT238672 Positive_regulation of Btc 3 0.67 0.5 0.29 5.00
141 INT206807 Gene_expression of MAPK6 1 0.15 2.44 0.22 5.00
142 INT186199 Binding of SCARB1 3 0.37 5.25 0.21 5.00
143 INT333601 Phosphorylation of IRF3 6 0.73 2.09 0.19 5.00
144 INT74298 Positive_regulation of Gene_expression of Nt5e 2 0.49 0.24 0.18 5.00
145 INT206805 Negative_regulation of Gene_expression of CD24 1 0.43 1.48 0.16 5.00
146 INT346493 Binding of MAVS 1 0.03 0.54 0.15 5.00
147 INT61789 Negative_regulation of Cdkn1a 2 0.41 1.35 0.13 5.00
148 INT205262 Gene_expression of Pbd1 1 0.10 0.43 0.13 5.00
149 INT205258 Regulation of Pbd1 1 0.07 0.18 0.12 5.00
150 INT279781 Gene_expression of MAVS 4 0.15 3.51 0.12 5.00
151 INT346495 Positive_regulation of Irak1 1 0.45 0.33 0.11 5.00
152 INT346483 Positive_regulation of IRAK4 1 0.45 0.33 0.11 5.00
153 INT346497 Negative_regulation of Phosphorylation of Cdkn1a 1 0.41 0.83 0.09 5.00
154 INT301361 Phosphorylation of Cdkn1a 2 0.79 1.21 0.09 5.00
155 INT290301 Regulation of Localization of JMJD6 1 0.03 1.25 0.08 5.00
156 INT290302 Localization of JMJD6 1 0.05 1.25 0.08 5.00
157 INT151469 Gene_expression of Ddn 17 0.59 2.13 0.08 5.00
158 INT234454 Regulation of Gene_expression of HCC 6 0.18 8.3 0.06 5.00
159 INT213915 Negative_regulation of Positive_regulation of ERBB2 2 0.41 1.09 0.05 5.00
160 INT205259 Positive_regulation of Pbd1 1 0.07 0.33 0.03 5.00
161 INT328278 Phosphorylation of IFIH1 2 0.08 1.27 0.03 5.00
162 INT346490 Phosphorylation of DDX58 1 0.07 1.03 0.03 5.00
163 INT205260 Binding of Pbd1 1 0.05 0.25 0 5.00
164 INT206806 Phosphorylation of CD24 2 0.63 1.35 0 5.00
165 INT346487 Negative_regulation of Phosphorylation of RXRA 1 0.01 0.63 0 5.00
166 INT342250 Negative_regulation of Gene_expression of Ercc1 1 0.40 0.99 0 5.00
167 INT346494 Phosphorylation of RXRA 1 0.01 0.63 0 5.00
168 INT205261 Localization of Pbd1 1 0.11 0.14 0 5.00
169 INT349191 Binding of Ddn 1 0.26 0.2 0 5.00
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