D:Bladder Cancer

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Disease Term
Synonyms Bladder Cancers, BLADDER CARCINOMA, Bladder Carcinomas, Bladder Dysplasia, BLADDER HYPERPLASIA, BLADDER NEOPLASIA, Bladder Neoplasm, Bladder Neoplasms, BLADDER SARCOMA, Bladder Sarcomata, Bladder Tumor
Documents 1043
Hot Single Events 200
Hot Interactions 48

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Bladder Cancer. They are ordered first by their relevance to Bladder Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT232006 Binding of Trp53 and Tsp1 1 0.06 0.75 0 100.00
2 INT161547 Trpv1 Regulation of Sorbs1 1 0.03 0.25 0.17 99.60
3 INT286988 Twist1 Positive_regulation of EGFR 1 0.17 2.01 0 99.52
4 INT223569 Binding of cy and Mri1 1 0.00 0.57 0.22 99.32
5 INT316478 Binding of Stat3 and Hist1h3f 1 0.05 1.08 0.03 98.72
6 INT307100 Trpv1 Regulation of Binding of Trpa1 1 0.31 1.81 0.97 98.56
7 INT307103 Trpa1 Regulation of Binding of Trpv1 1 0.31 1.81 0.97 98.56
8 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18 98.20
9 INT223570 Binding of Mri1 and Uhrf2 1 0.02 0.56 0.22 98.20
10 INT226907 Binding of E2f1 and Nfkb1 1 0.14 0.6 0.12 97.56
11 INT94523 Binding of MT2A and ALG1 1 0.16 0.72 0.09 94.40
12 INT179699 LPCAT3 Regulation of LHX2 1 0.00 0.31 0 94.20
13 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17 94.08
14 INT349051 Binding of EPCAM and SCFV 1 0.03 1.37 0 93.80
15 INT355036 CKAP4 Regulation of Positive_regulation of TP53 1 0.08 0.4 0.03 92.88
16 INT209047 Slc11a1 Positive_regulation of Localization of Il10 1 0.10 0.52 0.36 92.60
17 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22 92.32
18 INT262809 Il10 Positive_regulation of Regulation of Slc11a1 1 0.17 1.12 0.27 92.20
19 INT267156 Binding of VDR and SUGT1 1 0.04 3.4 0.09 91.72
20 INT208944 Pax3 Positive_regulation of Localization of Nfkb1 1 0.03 0.55 0.29 91.00
21 INT232004 Mapk8 Positive_regulation of Transcription of Fasl 1 0.05 0.65 0 90.88
22 INT232003 Cd36 Positive_regulation of Transcription of Fasl 1 0.10 0.66 0 90.88
23 INT232007 Ahsa1 Positive_regulation of Transcription of Fasl 1 0.03 0.65 0 90.88
24 INT196527 Positive_regulation of Binding of MMP1 and MMP2 1 0.44 0.74 0.51 90.72
25 INT196519 Positive_regulation of Binding of MMP1 and MMP9 1 0.42 0.74 0.51 90.72
26 INT196524 Binding of MMP1 and MMP9 1 0.31 0.74 0.51 90.32
27 INT196520 Binding of MMP1 and MMP2 1 0.33 0.74 0.51 90.32
28 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16 90.08
29 INT267137 ICAM1 Regulation of ITGAL 2 0.12 0.57 0.07 89.92
30 INT349050 Binding of EPCAM and ZNF845 1 0.02 1.54 0 89.20
31 INT355038 NRP1 Negative_regulation of CKAP4 1 0.02 1.23 0.29 88.80
32 INT314745 Binding of TP53 and Brca1 1 0.18 1.17 0 88.68
33 INT337062 Binding of VEGFA and NMI 1 0.07 1.12 0 88.56
34 INT208947 Pax3 Positive_regulation of Tacr1 Positive_regulation of Localization of Nfkb1 1 0.03 0.55 0.29 87.88
35 INT208940 Pax3 Positive_regulation of Tacr1 1 0.07 0.55 0.29 87.88
36 INT208941 Positive_regulation of Pax3 Positive_regulation of Tacr1 1 0.05 0.55 0.29 87.88
37 INT226913 Slc11a1 Positive_regulation of Gene_expression of IL8 1 0.05 0.63 0.07 87.04
38 INT264733 Hes1 Regulation of Mir199b 1 0.05 0.43 0 87.00
39 INT192167 Negative_regulation of Binding of BAK1 and BCL2 2 0.05 1.89 0.03 85.56
40 INT192166 Negative_regulation of Binding of BAK1 and BCL2L1 1 0.05 1.06 0.03 85.56
41 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33 85.48
42 INT196523 Binding of MMP2 and TIMP1 3 0.43 1.94 0.85 85.48
43 INT196526 Binding of TIMP1 and TIMP2 1 0.45 1.49 0.71 85.48
44 INT192164 Binding of BAK1 and BCL2 3 0.04 2.8 0.03 85.24
45 INT192165 Binding of BAK1 and BCL2L1 2 0.06 1.35 0.03 85.24
46 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78 85.24
47 INT196521 Binding of MMP2 and TIMP2 1 0.30 0.68 0.52 85.24
48 INT226912 Slc11a1 Positive_regulation of Localization of IL8 1 0.05 0.58 0.08 82.16
49 INT262810 Slc11a1 Positive_regulation of Gene_expression of Il10 1 0.20 0.97 0.27 79.44
50 INT316485 Stat3 Positive_regulation of Transcription of Ccnd1 1 0.23 1.27 0.04 78.08
51 INT316499 Stat3 Positive_regulation of Transcription of MYC 1 0.55 1.27 0.04 77.04
52 INT316486 Stat3 Positive_regulation of Transcription of Cdc2b 1 0.28 1.27 0.04 76.48
53 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89 76.08
54 INT316489 Stat3 Positive_regulation of Transcription of Ccnb1 1 0.02 1.27 0.04 76.00
55 INT312372 Binding of MME and TCHP 1 0.06 1.56 0 73.60
56 INT316497 Negative_regulation of Stat3 Negative_regulation of Gene_expression of VEGFA 1 0.13 0.93 0 73.04
57 INT314743 Binding of RAD51 and Brca1 1 0.06 1.06 0 73.00
58 INT208942 Positive_regulation of Mapk14 Positive_regulation of Positive_regulation of Jun 1 0.10 0.42 0.2 72.96
59 INT226911 Slc11a1 Positive_regulation of Gene_expression of Il6 1 0.09 1.12 0.24 72.72
60 INT314742 Binding of RAD51 and Brca2 1 0.06 1.05 0 72.60
61 INT226910 Slc11a1 Positive_regulation of Localization of Nfkb1 1 0.11 0.62 0.11 71.68
62 INT301122 Tgm7 Negative_regulation of Akt1 1 0.38 2.78 0.07 71.28
63 INT226899 Slc11a1 Positive_regulation of Localization of Gtf3a 1 0.00 0.54 0.11 70.88
64 INT302295 PPARA Regulation of OAS2 1 0.01 0.72 0.17 69.76
65 INT161548 Sorbs1 Positive_regulation of Gene_expression of Ros1 1 0.22 0.07 0 69.56
66 INT113959 TNF Positive_regulation of Gene_expression of IK 1 0.02 0.66 0.69 68.16
67 INT200099 OLR1 Negative_regulation of Gene_expression of VCAM1 1 0.01 0.85 0.13 67.64
68 INT314692 Binding of TBX2 and TBX3 1 0.27 0.84 0 67.52
69 INT314682 Binding of TBX2 and TBX4 1 0.16 0.84 0 67.28
70 INT339699 LDLR Positive_regulation of SREBF2 1 0.08 1.08 0 67.04
71 INT339694 LDLR Positive_regulation of Gene_expression of SREBF2 1 0.08 1.08 0 67.04
72 INT339693 HMGCR Positive_regulation of SREBF2 1 0.05 0.54 0 67.04
73 INT339709 HMGCR Positive_regulation of Gene_expression of SREBF2 1 0.05 0.54 0 67.04
74 INT221122 IFN1@ Regulation of Cdc42ep3 1 0.01 0.56 0 66.96
75 INT314693 Binding of TBX2 and TBX5 1 0.16 0.84 0 66.92
76 INT301127 Tgm7 Regulation of Positive_regulation of Akt1 1 0.47 0.48 0 66.04
77 INT182607 Binding of MLH1 and MSH3 1 0.04 0.81 0.11 64.40
78 INT209043 Binding of Fn1 and Slc11a1 3 0.03 1.91 0.78 62.12
79 INT182606 Binding of MSH2 and MSH3 1 0.12 1.4 0.21 61.60
80 INT297352 KLF2 Regulation of PPARA 1 0.12 1.31 0.35 57.76
81 INT253996 Binding of Cxcr2 and Cxcr4 1 0.18 0.81 0.44 56.88
82 INT301129 Tgm7 Negative_regulation of Akt1 Negative_regulation of Localization of Mmp2 1 0.38 0.55 0 56.64
83 INT272441 Binding of IFNA2 and Slc11a1 1 0.02 0.97 0 55.28
84 INT199366 DST Positive_regulation of Macf1 1 0.01 1.14 0 55.20
85 INT232005 Binding of Cd36 and Tsp1 2 0.25 1.81 0.16 54.00
86 INT339707 TRO Positive_regulation of CYP3A4 1 0.12 0.97 0.04 53.44
87 INT339700 CYP2B6 Positive_regulation of CYP3A4 1 0.13 0.3 0 53.44
88 INT339710 TRO Positive_regulation of CYP2B6 1 0.09 0.3 0 53.00
89 INT314740 Binding of ESR1 and Brca1 1 0.16 0.69 0 50.88
90 INT182950 Binding of VDR and NR1H4 5 0.03 1.16 0 47.36
91 INT343157 ACSL4 Regulation of Gene_expression of ALOX15 1 0.01 0.67 0.07 45.08
92 INT197546 NFE2L2 Regulation of Gene_expression of ABCC2 1 0.17 0.72 0.04 43.68
93 INT260070 Binding of PHF2 and SPTLC1 1 0.17 1.93 0.1 40.28
94 INT199360 Igf2 Regulation of Gene_expression of Lyve1 1 0.30 1.13 0 39.28
95 INT208943 Nfkb1 Positive_regulation of Nkx2-5 1 0.11 0.38 0.08 39.04
96 INT208945 Nkx2-5 Positive_regulation of Gene_expression of Nppa 1 0.03 0.33 0.05 39.04
97 INT196522 Binding of MMP1 and TIMP1 1 0.39 0.29 0.53 38.60
98 INT208937 Nfkb1 Positive_regulation of Gene_expression of Nppa 1 0.04 0.38 0.08 38.60
99 INT330956 Binding of TEP1 and NR1H4 1 0.00 1.07 0 37.16
100 INT330957 Binding of TEP1 and VDR 1 0.01 1.07 0 37.16
101 INT220527 Nme1 Negative_regulation of Positive_regulation of Vegfa 1 0.00 1.23 0.12 36.88
102 INT264738 Mir199b Regulation of Gene_expression of Hes1 1 0.08 0.89 0 34.36
103 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48 32.40
104 INT334423 Binding of SPINK1 and Cea 1 0.02 2.53 0.17 29.68
105 INT350106 Binding of SLC4A3 and SLC4A1 1 0.13 2.78 0.09 28.68
106 INT253997 Binding of Cd200r1 and Mif 1 0.03 1.02 0.46 28.16
107 INT221114 Slc11a1 Negative_regulation of Upk1a 1 0.23 0.37 0 27.88
108 INT221113 Slc11a1 Negative_regulation of Upk1b 1 0.19 0.37 0 27.48
109 INT240271 Binding of GDNF and RET 1 0.09 1.04 0 26.00
110 INT226905 Slc11a1 Regulation of Nfkb1 1 0.04 0.41 0.03 25.00
111 INT209049 Slc11a1 Positive_regulation of Localization of Il12a 1 0.04 0.09 0.44 24.16
112 INT305001 Binding of ACAN and TNFAIP6 1 0.28 1.22 0.14 23.84
113 INT314680 Positive_regulation of TBX2 Negative_regulation of CDKN2A 1 0.34 1.16 0 22.76
114 INT314685 TBX2 Negative_regulation of CDKN2A 1 0.32 1.16 0 22.12
115 INT226906 Binding of Ido1 and Il6 1 0.07 0.67 0.08 21.92
116 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52 21.84
117 INT191413 Tert Positive_regulation of Nqo1 1 0.02 0.84 0 18.88
118 INT264734 Mir199b Negative_regulation of Negative_regulation of Hes1 1 0.07 0.1 0 16.52
119 INT208019 Gbp1 Positive_regulation of Gene_expression of Egf 1 0.09 0.56 0 13.64
120 INT264729 Mir199b Regulation of Hes1 1 0.05 0.25 0 13.44
121 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25 5.00
122 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
123 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
124 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
125 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
126 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85 5.00
127 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83 5.00
128 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27 5.00
129 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16 5.00
130 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15 5.00
131 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
132 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 5.00
133 INT207149 Binding of F2r and Par2 1 0.17 1.64 0.92 5.00
134 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88 5.00
135 INT254004 Cxcl12 Positive_regulation of Cxcr4 1 0.47 1.29 0.86 5.00
136 INT232417 Binding of Mtx1 and Ifx 1 0.04 0.99 0.86 5.00
137 INT253995 Binding of Cxcl12 and Cyp3a23/3a1 1 0.06 1.28 0.85 5.00
138 INT208946 Positive_regulation of Tacr1 Positive_regulation of Gene_expression of S100a8 1 0.02 1.11 0.8 5.00
139 INT258644 Binding of CCL2 and CCL5 1 0.36 1.6 0.74 5.00
140 INT258643 Positive_regulation of Binding of CCL2 and CCL5 1 0.49 1.61 0.74 5.00
141 INT209040 Il3 Positive_regulation of Cxcl1 1 0.04 0.38 0.73 5.00
142 INT209061 Il3 Positive_regulation of Elf1 1 0.06 0.38 0.73 5.00
143 INT209035 Il2 Positive_regulation of Ccr1 1 0.00 0.38 0.73 5.00
144 INT209037 Il4 Positive_regulation of Csf2 1 0.03 0.38 0.73 5.00
145 INT209038 Il4 Positive_regulation of Ccr1 1 0.01 0.38 0.73 5.00
146 INT209048 Il3 Positive_regulation of Il17a 1 0.03 0.38 0.73 5.00
147 INT209058 Il4 Positive_regulation of Elf1 1 0.08 0.38 0.73 5.00
148 INT209052 Il2 Positive_regulation of Il17a 1 0.03 0.38 0.73 5.00
149 INT209034 Il4 Positive_regulation of Il17a 1 0.04 0.38 0.73 5.00
150 INT209065 Il3 Positive_regulation of Ccr1 1 0.00 0.38 0.73 5.00
151 INT209053 Il2 Positive_regulation of Elf1 1 0.06 0.38 0.73 5.00
152 INT209064 Il4 Positive_regulation of Cxcl1 1 0.05 0.38 0.73 5.00
153 INT209036 Il2 Positive_regulation of Cxcl1 1 0.04 0.38 0.73 5.00
154 INT209051 Il2 Positive_regulation of Csf2 1 0.02 0.38 0.73 5.00
155 INT209062 Il3 Positive_regulation of Csf2 1 0.02 0.38 0.73 5.00
156 INT209057 Il6 Positive_regulation of Csf2 1 0.03 0.38 0.72 5.00
157 INT209029 Il12b Positive_regulation of Elf1 1 0.24 0.37 0.72 5.00
158 INT209045 Il10 Positive_regulation of Csf2 1 0.03 0.37 0.72 5.00
159 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72 5.00
160 INT209030 Il12b Positive_regulation of Cxcl1 1 0.16 0.37 0.72 5.00
161 INT209039 Il6 Positive_regulation of Il17a 1 0.05 0.38 0.72 5.00
162 INT209056 Il6 Positive_regulation of Elf1 1 0.10 0.38 0.72 5.00
163 INT209028 Il12b Positive_regulation of Il17a 1 0.12 0.37 0.72 5.00
164 INT209059 Il6 Positive_regulation of Cxcl1 1 0.06 0.38 0.72 5.00
165 INT209050 Il10 Positive_regulation of Elf1 1 0.10 0.37 0.72 5.00
166 INT209041 Il10 Positive_regulation of Ccr1 1 0.01 0.37 0.72 5.00
167 INT209042 Il10 Positive_regulation of Cxcl1 1 0.07 0.37 0.72 5.00
168 INT209060 Il6 Positive_regulation of Ccr1 1 0.01 0.38 0.72 5.00
169 INT209032 Il12b Positive_regulation of Csf2 1 0.08 0.37 0.72 5.00
170 INT209044 Il10 Positive_regulation of Il17a 1 0.05 0.37 0.72 5.00
171 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71 5.00
172 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69 5.00
173 INT209054 Il17a Positive_regulation of Gene_expression of Il6 1 0.10 0.45 0.65 5.00
174 INT209063 Slc11a1 Positive_regulation of Il17a 1 0.11 0.4 0.65 5.00
175 INT209055 S100a8 Positive_regulation of Gene_expression of Il6 1 0.01 0.45 0.64 5.00
176 INT207111 F2 Positive_regulation of Pawr 2 0.07 1.38 0.64 5.00
177 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55 5.00
178 INT253998 Cyp3a23/3a1 Positive_regulation of Binding of Cxcl12 1 0.10 0.65 0.55 5.00
179 INT253990 Cyp3a23/3a1 Positive_regulation of Cxcl12 1 0.09 0.65 0.55 5.00
180 INT213809 F2 Positive_regulation of F2rl3 2 0.12 0.61 0.5 5.00
181 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 5.00
182 INT321598 Binding of MLL and TNF 1 0.05 1.07 0.49 5.00
183 INT240441 Ltb4r1 Positive_regulation of PPARA 1 0.03 1.01 0.47 5.00
184 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46 5.00
185 INT240442 Binding of PPARA and Ltb4r1 1 0.02 0.94 0.46 5.00
186 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
187 INT189309 Binding of MME and PENK 1 0.15 1.16 0.42 5.00
188 INT207110 Adam3 Regulation of Gene_expression of Eef1a1 1 0.01 1 0.41 5.00
189 INT316493 Il6 Positive_regulation of Il11ra1 1 0.64 1.69 0.4 5.00
190 INT182489 Gene_expression of AGTR2 Positive_regulation of Gene_expression of AGTR1 1 0.26 0.92 0.4 5.00
191 INT207113 Nfkbia Negative_regulation of Nfkb1 1 0.11 0.96 0.4 5.00
192 INT173977 Binding of TNF and Ighg1 1 0.03 0.28 0.39 5.00
193 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38 5.00
194 INT182497 IL1B Regulation of Localization of GH1 1 0.00 0.84 0.38 5.00
195 INT182492 IL1B Regulation of Gene_expression of IGF1 1 0.01 0.83 0.38 5.00
196 INT235432 Ppara Negative_regulation of Gene_expression of Cpox 1 0.01 1 0.37 5.00
197 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35 5.00
198 INT183786 IL6 Negative_regulation of INS 1 0.09 1.61 0.35 5.00
199 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34 5.00
200 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Bladder Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Bladder Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 100.00
2 INT221108 Negative_regulation of Slc11a1 5 0.33 3.76 0.69 100.00
3 INT166289 Localization of Bts1 1 0.61 0.65 0.17 100.00
4 INT199345 Gene_expression of Lyve1 11 0.50 8.44 0.89 100.00
5 INT45840 Positive_regulation of Gene_expression of Ptgs1 35 0.50 16.07 20.49 100.00
6 INT166290 Gene_expression of Bts1 1 0.54 0.37 0.17 100.00
7 INT134798 Gene_expression of ANXA1 15 0.75 13.94 2.99 100.00
8 INT68394 Gene_expression of KISS1 15 0.73 5.33 2.03 100.00
9 INT121171 Negative_regulation of Gene_expression of Ngfr 6 0.58 3.46 3.89 100.00
10 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 100.00
11 INT8801 Gene_expression of Csf3 71 0.74 45.6 10.83 99.98
12 INT46530 Gene_expression of Pthlh 15 0.78 11.23 1.7 99.98
13 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 99.96
14 INT337065 Negative_regulation of NMI 1 0.07 0.96 0 99.96
15 INT284122 Gene_expression of ZNF845 6 0.07 6.67 0.27 99.92
16 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.88
17 INT231987 Gene_expression of Tsp1 66 0.67 62.58 1.78 99.84
18 INT231995 Positive_regulation of Gene_expression of Tsp1 15 0.60 15.21 0.18 99.84
19 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 99.84
20 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 99.84
21 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.84
22 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 99.84
23 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.84
24 INT176495 Gene_expression of MMP28 6 0.57 3.82 1.64 99.84
25 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 99.84
26 INT94534 Gene_expression of MT2A 8 0.75 11.28 1.76 99.80
27 INT231986 Regulation of Gene_expression of Tsp1 1 0.53 3.16 0.13 99.80
28 INT121170 Positive_regulation of Gene_expression of Ngfr 10 0.64 9.32 3.94 99.80
29 INT94535 Negative_regulation of Gene_expression of MT2A 1 0.34 1.7 0.07 99.80
30 INT262806 Positive_regulation of Positive_regulation of Hand1 3 0.28 1.58 0.13 99.80
31 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 99.78
32 INT253974 Binding of Cxcr4 22 0.47 12.26 5.95 99.76
33 INT57290 Positive_regulation of IL17B 1 0.69 2.09 1.57 99.76
34 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 99.74
35 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 99.72
36 INT130363 Localization of Thbs1 9 0.75 4.99 0.76 99.72
37 INT231980 Gene_expression of Upk2 1 0.39 5.1 0.07 99.68
38 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.68
39 INT266535 Phosphorylation of JUP 3 0.79 0.63 0.49 99.68
40 INT355094 Phosphorylation of CKAP4 1 0.60 0.62 0.09 99.68
41 INT194625 Gene_expression of GSK 18 0.75 9.02 3.23 99.68
42 INT220399 Positive_regulation of Cyp19a1 4 0.43 2.2 0.07 99.66
43 INT94533 Positive_regulation of MT1X 1 0.44 1.78 0.14 99.64
44 INT46016 Gene_expression of Ngfr 69 0.77 41.22 19.8 99.64
45 INT94540 Gene_expression of MT1X 6 0.49 5.51 0.28 99.60
46 INT94541 Positive_regulation of Gene_expression of MT1X 1 0.44 1.84 0.06 99.60
47 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 99.60
48 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 99.60
49 INT85417 Positive_regulation of Gene_expression of IK 17 0.09 9.38 5.73 99.60
50 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 99.56
51 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 99.54
52 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 99.54
53 INT221119 Negative_regulation of Negative_regulation of HLA-A 1 0.01 0.61 0 99.52
54 INT172558 Positive_regulation of Cdh1 11 0.49 8.92 0.42 99.52
55 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 99.50
56 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 99.48
57 INT26501 Positive_regulation of Gene_expression of MMP2 51 0.67 39 15.16 99.48
58 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 99.48
59 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17 99.48
60 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 99.48
61 INT94538 Gene_expression of ALG1 1 0.37 3.6 0.31 99.44
62 INT94526 Positive_regulation of Gene_expression of ALG1 1 0.33 1.9 0.15 99.44
63 INT94530 Negative_regulation of Gene_expression of ALG1 1 0.20 0.55 0.07 99.44
64 INT123733 Gene_expression of Fhit 5 0.78 12.34 0.26 99.40
65 INT178174 Gene_expression of Tnfsf10 78 0.76 56.83 8.64 99.40
66 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42 99.40
67 INT179729 Gene_expression of MBOAT7 2 0.17 1.05 0.07 99.40
68 INT179734 Positive_regulation of Gene_expression of MBOAT7 1 0.13 0.32 0 99.40
69 INT237227 Negative_regulation of Gene_expression of Plk1 1 0.08 0.54 0 99.36
70 INT21678 Negative_regulation of B2m 20 0.55 10.11 3.12 99.32
71 INT62430 Negative_regulation of HLA-A 5 0.32 4.3 1.63 99.32
72 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63 99.32
73 INT100955 Binding of DNA2 1 0.01 0.27 0.09 99.28
74 INT100958 Regulation of Binding of DNA2 1 0.01 0.27 0.09 99.28
75 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 99.26
76 INT154147 Gene_expression of TP73 7 0.34 3.97 0.19 99.24
77 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32 99.22
78 INT8546 Positive_regulation of MUC16 99 0.69 74.98 11.26 99.16
79 INT200395 Gene_expression of DUOXA1 2 0.11 0.59 0 99.16
80 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 99.12
81 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 99.12
82 INT199139 Transcription of MT3 1 0.69 1.96 0.17 99.12
83 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 99.12
84 INT199134 Negative_regulation of Transcription of MT3 1 0.37 1.17 0.09 99.12
85 INT55944 Positive_regulation of Cpox 214 0.57 105.14 81.4 99.12
86 INT36678 Binding of TIMP1 33 0.36 14.99 7.87 99.12
87 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75 99.08
88 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62 99.08
89 INT237226 Gene_expression of Plk1 3 0.59 0.78 0 99.08
90 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 99.04
91 INT154151 Positive_regulation of TP73 5 0.67 5.71 0.52 99.04
92 INT155992 Gene_expression of THBD 16 0.66 17 1.24 99.04
93 INT152210 Positive_regulation of IFNGR1 2 0.63 2.64 0.3 99.02
94 INT231983 Localization of Tsp1 9 0.72 7.44 0.4 99.00
95 INT143006 Gene_expression of A1BG 23 0.73 22.92 0.88 99.00
96 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 98.96
97 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 98.96
98 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 98.96
99 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 98.96
100 INT231991 Negative_regulation of Gene_expression of Tsp1 6 0.51 7.3 0.18 98.88
101 INT132903 Gene_expression of Cd34 65 0.72 33.95 2.2 98.86
102 INT96741 Gene_expression of Cxcr4 62 0.78 32.3 22.14 98.84
103 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5 98.84
104 INT49219 Gene_expression of Hrh1 28 0.75 13.77 14.99 98.84
105 INT85340 Positive_regulation of Slc22a13 1 0.04 0.95 0.11 98.84
106 INT102816 Positive_regulation of TCEAL1 6 0.37 7.08 0.96 98.84
107 INT67589 Gene_expression of MT1E 8 0.51 7.52 1.09 98.80
108 INT199137 Negative_regulation of Gene_expression of MT3 1 0.43 1.49 0.14 98.80
109 INT94524 Gene_expression of MT1A 6 0.39 1.66 1.75 98.80
110 INT94527 Gene_expression of MT1B 2 0.36 1.2 0.11 98.80
111 INT20006 Gene_expression of MT1F 27 0.68 19.55 3.18 98.80
112 INT94542 Gene_expression of MT1G 1 0.17 1.12 0.08 98.80
113 INT94528 Gene_expression of MT1H 1 0.36 1.11 0.08 98.80
114 INT199135 Negative_regulation of Localization of MT3 1 0.43 0.81 0.06 98.80
115 INT8065 Binding of AGT 54 0.48 20.54 10.85 98.80
116 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51 98.78
117 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 98.76
118 INT149197 Negative_regulation of NFKB2 14 0.25 10.55 4.46 98.76
119 INT100957 Gene_expression of DNA2 1 0.04 0.28 0.1 98.76
120 INT100953 Negative_regulation of Gene_expression of DNA2 1 0.03 0.28 0.1 98.76
121 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63 98.72
122 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61 98.72
123 INT99608 Transcription of MMP9 18 0.65 9.67 4.11 98.72
124 INT71875 Localization of Nfkb1 92 0.78 48.13 22.94 98.72
125 INT187022 Positive_regulation of Transcription of MMP9 3 0.45 3.27 0.34 98.72
126 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 98.72
127 INT89603 Regulation of Negative_regulation of Cpox 11 0.30 10.59 6.28 98.72
128 INT221109 Regulation of Upk2 2 0.28 0.9 0.1 98.70
129 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 98.68
130 INT301687 Negative_regulation of Phosphorylation of IL12A 1 0.05 0.94 0.37 98.68
131 INT47301 Gene_expression of Ctsl 27 0.76 7.72 9.32 98.64
132 INT196929 Positive_regulation of E2f1 10 0.66 4.29 0.19 98.64
133 INT94537 Gene_expression of Metallothionein isoform 1 1 0.11 1.29 0.14 98.60
134 INT94536 Negative_regulation of Gene_expression of metallothionein isoform 1 1 0.06 0.54 0.07 98.60
135 INT231981 Negative_regulation of Localization of Tsp1 1 0.37 1.98 0 98.56
136 INT49488 Gene_expression of mMCP-7 37 0.75 26.11 7.68 98.56
137 INT134379 Binding of Trpa1 13 0.48 7.16 7.27 98.56
138 INT306170 Regulation of PRPF19 1 0.07 9.66 0.03 98.52
139 INT66038 Positive_regulation of Ngfr 32 0.69 26.07 11.75 98.52
140 INT120401 Positive_regulation of PIK3CD 33 0.45 14.89 7.37 98.52
141 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 98.50
142 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5 98.48
143 INT199138 Gene_expression of MT3 1 0.78 4.07 0.3 98.44
144 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 98.44
145 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 98.42
146 INT55736 Transcription of MMP2 11 0.68 5.78 2.28 98.36
147 INT55738 Positive_regulation of Transcription of MMP2 3 0.65 1.79 0.92 98.36
148 INT231994 Regulation of Localization of Tsp1 1 0.39 0.99 0 98.36
149 INT241861 Regulation of EPCAM 7 0.17 7.23 1.22 98.36
150 INT199136 Localization of MT3 1 0.75 0.8 0.06 98.32
151 INT231984 Negative_regulation of Tsp1 5 0.51 6.01 0.28 98.28
152 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03 98.28
153 INT115964 Negative_regulation of ITGAL 7 0.34 3.76 0.86 98.26
154 INT153777 Gene_expression of SRL 2 0.65 1.72 0.06 98.24
155 INT88245 Gene_expression of Slc11a1 42 0.53 18.86 6.2 98.20
156 INT103210 Localization of MMP1 43 0.78 12.15 15.13 98.20
157 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 98.20
158 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 98.20
159 INT51150 Positive_regulation of HTC2 10 0.67 6.8 2.95 98.20
160 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 98.16
161 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 98.16
162 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 98.12
163 INT78320 Gene_expression of EPCAM 57 0.75 50.34 7.53 98.12
164 INT139203 Gene_expression of CKAP4 2 0.75 1.39 0.14 98.08
165 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25 98.08
166 INT355095 Negative_regulation of Gene_expression of CKAP4 1 0.31 0.52 0 98.08
167 INT76814 Positive_regulation of Gene_expression of Tacr1 13 0.69 6.11 8.42 98.08
168 INT355085 Regulation of Gene_expression of CKAP4 1 0.33 0.35 0 98.04
169 INT72949 Binding of Mif 31 0.46 23.12 11.65 97.96
170 INT103094 Binding of PPARA 308 0.47 177.26 34.75 97.96
171 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 97.92
172 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 97.92
173 INT4830 Binding of Trpv1 158 0.48 45.11 84.2 97.92
174 INT63365 Gene_expression of Spg21 21 0.65 12.9 7.37 97.84
175 INT99454 Gene_expression of NAT2 4 0.67 1.76 0.43 97.80
176 INT100952 Negative_regulation of Gene_expression of NAT2 2 0.35 0.34 0.18 97.80
177 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 97.72
178 INT190572 Gene_expression of Ctsh 1 0.50 1.12 0.06 97.68
179 INT100956 Regulation of Gene_expression of NAT2 1 0.28 0.27 0.09 97.64
180 INT175995 Gene_expression of HEPACAM 12 0.28 12.45 0.58 97.60
181 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 97.56
182 INT178306 Negative_regulation of Gene_expression of Gopc 71 0.37 26.43 9.74 97.48
183 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 97.48
184 INT175520 Gene_expression of Igf2 43 0.78 48.93 1.21 97.48
185 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 97.44
186 INT221120 Regulation of Gene_expression of HLA-DMA 1 0.00 0.62 0 97.44
187 INT65125 Gene_expression of Tacr1 81 0.77 23.9 38.35 97.38
188 INT235659 Gene_expression of EFNA1 1 0.45 22.92 0.06 97.24
189 INT235656 Positive_regulation of Gene_expression of EFNA1 1 0.40 8.86 0 97.24
190 INT229461 Regulation of Tsp1 5 0.53 6.1 0.16 97.20
191 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53 97.16
192 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 97.12
193 INT78297 Gene_expression of CD59 31 0.72 24.11 3.18 97.12
194 INT209018 Positive_regulation of Slc11a1 11 0.55 7.12 3.83 97.08
195 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 97.08
196 INT154150 Regulation of TP73 3 0.15 2.81 0.24 97.04
197 INT140998 Regulation of GSK 3 0.60 1.13 0.62 97.04
198 INT105336 Regulation of AKT1 52 0.56 32.53 4.89 97.04
199 INT176147 Regulation of Phosphorylation of AKT1 14 0.41 6.41 1.13 97.04
200 INT94525 Transcription of MT1X 1 0.43 1.08 0.07 97.00
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