D:Blindness

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Disease Term
Synonyms Acquired Blindness, Amauroses, Amaurosis, BLIND VISION, Blindness Acquired, BLINDNESS COMPLETE, BLINDNESS HYSTERICAL, Blindness Legal, Blindness Monocular, Blindness Transient, Cannot See
Documents 1583
Hot Single Events 190
Hot Interactions 12

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Blindness. They are ordered first by their relevance to Blindness and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT316015 AIC Regulation of ERN1 1 0.08 0.1 0.05 100.00
2 INT297848 Binding of Fzd4 and Ndp 1 0.04 1.19 0 97.96
3 INT297855 Binding of Ndp and Wnt1 1 0.38 1.18 0 97.96
4 INT314851 Positive_regulation of Binding of Neurod1 and Atoh7 1 0.23 0.27 0 93.48
5 INT314860 Gene_expression of Atoh7 Positive_regulation of 1190002H23Rik 1 0.02 0.27 0 93.48
6 INT314864 Binding of Neurod1 and Positive_regulation of Gene_expression of Atoh7 1 0.25 0.27 0 93.48
7 INT314863 Binding of Neurod1 and Atoh7 1 0.18 0.27 0 92.76
8 INT314861 Gdf11 Regulation of Gene_expression of Atoh7 1 0.20 0.26 0 87.80
9 INT274285 AGT Positive_regulation of Gene_expression of VEGFA 1 0.01 0.98 0.03 83.80
10 INT274288 AGT Positive_regulation of Gene_expression of Vegfa 1 0.07 0.98 0.03 83.80
11 INT274284 AGT Positive_regulation of Binding of VEGFA 1 0.01 0.99 0.03 83.80
12 INT234795 Negative_regulation of CHM Negative_regulation of RAB27A 1 0.01 0.8 0 82.48
13 INT286422 Binding of Cdc42ep5 and Dock4 1 0.01 0.84 0 79.44
14 INT355327 Binding of Nes and Prom1 1 0.11 1.49 0.06 77.20
15 INT262820 Binding of Aif1 and Serpinf1 1 0.01 1.3 0.27 76.16
16 INT301178 UCP2 Negative_regulation of ROS1 1 0.29 1.41 0 74.84
17 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0 74.44
18 INT314854 Gdf11 Regulation of Atoh7 1 0.51 0.21 0 74.12
19 INT314857 Atoh7 Regulation of Pou4f2 1 0.21 0.21 0 73.52
20 INT245823 Binding of Plg and Plg 1 0.03 1.41 0 66.24
21 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16 65.40
22 INT260529 Twist1 Positive_regulation of Gene_expression of Vegfa 1 0.04 0.54 0 65.40
23 INT302507 Binding of GLC1F and OPA1 1 0.01 3.76 0 63.12
24 INT300446 VEGFA Positive_regulation of Flt1 1 0.09 2.62 0.07 57.52
25 INT245833 Plg Negative_regulation of VEGFA 1 0.05 2.21 0.04 57.52
26 INT300445 VEGFA Positive_regulation of Vegfa 1 0.03 1.33 0.03 57.52
27 INT245827 Plg Negative_regulation of Vegfa 1 0.14 1.3 0 57.52
28 INT355438 Gene_expression of Pdia3 Negative_regulation of Gene_expression of Ddit3 1 0.05 4.79 0.06 57.48
29 INT275667 Binding of CYP1B1 and GLC3C 1 0.27 0.99 0 55.48
30 INT229983 Binding of CFH and Crp 2 0.14 1.48 0 55.40
31 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 51.04
32 INT212139 Slc4a3 Positive_regulation of Cl 1 0.07 0 0.12 50.00
33 INT212138 Slc4a3 Positive_regulation of Gene_expression of Cl 1 0.07 0 0.12 50.00
34 INT233904 NLRP3 Positive_regulation of AGT 1 0.06 0.81 0.17 49.40
35 INT262824 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.39 1.56 0.37 47.68
36 INT275562 Il1 Regulation of Gene_expression of Cxcl2 1 0.02 1.41 0.64 40.68
37 INT339581 Binding of TIMP1 and TIMP3 1 0.30 0.54 0 40.40
38 INT262822 Serpinf1 Negative_regulation of Negative_regulation of 1190002H23Rik 1 0.07 1.27 0.18 39.84
39 INT340816 Tnfrsf14 Regulation of Gene_expression of Btla 1 0.11 1.09 0.18 35.28
40 INT340822 Trav6-3 Regulation of Gene_expression of Btla 1 0.07 0.97 0.15 35.28
41 INT314853 Binding of Cdc7 and Tgfbr3 1 0.24 0.09 0 35.24
42 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82 29.52
43 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4 29.52
44 INT166792 Binding of CD44 and HRAS 3 0.12 1.49 0.37 29.40
45 INT300449 VEGFA Positive_regulation of Protein_catabolism of Ppp2r2b 1 0.00 1.51 0.05 29.36
46 INT245832 VEGFA Positive_regulation of Phosphorylation of Ocln 1 0.04 1.61 0 27.72
47 INT245830 VEGFA Regulation of Ocln 1 0.02 0.83 0 27.72
48 INT339580 TIMP3 Positive_regulation of ABCA1 1 0.16 0.73 0 26.56
49 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 25.00
50 INT339586 TIMP3 Positive_regulation of RPE 1 0.16 0.72 0 24.88
51 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14 23.84
52 INT245821 Binding of Ppp2r2b and Ocln 1 0.00 0.81 0 22.76
53 INT314869 Binding of Gdf11 and Tgfbr3 1 0.29 0.14 0 20.20
54 INT314871 Binding of Tgfbr3 and Atoh7 1 0.33 0.09 0 20.20
55 INT243119 Binding of amd and Sod2 1 0.29 3.25 0.06 18.72
56 INT314855 Binding of Gdf11 and Atoh7 1 0.40 0.14 0 18.72
57 INT175911 Binding of SERPINE1 and CNBP 1 0.01 1.02 0.22 17.00
58 INT174657 IL8 Positive_regulation of Gene_expression of LTBR 1 0.01 1.53 0.3 15.28
59 INT174659 TNF Positive_regulation of Gene_expression of LTBR 1 0.22 1.54 0.3 15.28
60 INT175910 SERPINE1 Negative_regulation of PLAU 1 0.06 1.01 0.22 15.04
61 INT174658 TNF Positive_regulation of Gene_expression of ITGAM 1 0.16 1.54 0.3 14.88
62 INT274156 Negative_regulation of Cabin1 Negative_regulation of Gene_expression of Vegfa 1 0.08 0.28 0.09 14.52
63 INT234831 Binding of SPTLC1 and Abo 1 0.00 1.61 0.23 14.40
64 INT314858 Binding of Gdf11 and Ltbp3 1 0.39 0.31 0 12.00
65 INT290046 RAB27A Regulation of RPE 1 0.03 0.75 0 11.28
66 INT302493 Binding of AGRP and IMPACT 1 0.25 0.53 0 11.24
67 INT298703 Angpt1 Regulation of Tek 1 0.12 0.27 0.03 11.00
68 INT290104 Myo7a Regulation of RPE 1 0.03 0.75 0 11.00
69 INT170668 GOPC Regulation of CRP 1 0.07 0.32 0.04 10.96
70 INT170666 GOPC Regulation of ANGPTL5 1 0.06 0.32 0.04 10.96
71 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
72 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 5.00
73 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3 5.00
74 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 5.00
75 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
76 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22 5.00
77 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 5.00
78 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09 5.00
79 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09 5.00
80 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99 5.00
81 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 5.00
82 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88 5.00
83 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
84 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
85 INT282129 Il10 Positive_regulation of Icam1 1 0.56 3.12 0.82 5.00
86 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82 5.00
87 INT111080 Binding of CA1 and CA2 2 0.02 1.62 0.73 5.00
88 INT170558 Binding of Myoc and Narf 1 0.04 3.03 0.63 5.00
89 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 5.00
90 INT290594 BDNF Positive_regulation of Localization of S100B 1 0.08 0.6 0.57 5.00
91 INT265463 CSPG4 Negative_regulation of Gene_expression of IL6 1 0.06 1.6 0.56 5.00
92 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 0.31 1.92 0.56 5.00
93 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 5.00
94 INT249717 Binding of NCL and MCF2L 1 0.23 0 0.54 5.00
95 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 5.00
96 INT194595 Binding of TNFSF10 and TNFRSF10B 4 0.15 9.3 0.53 5.00
97 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5 5.00
98 INT335851 Snrpc Positive_regulation of Il10 1 0.01 1.17 0.5 5.00
99 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49 5.00
100 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48 5.00
101 INT335850 Snrpc Negative_regulation of Gene_expression of Isl1 1 0.00 1.51 0.45 5.00
102 INT262815 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.39 2.73 0.44 5.00
103 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43 5.00
104 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43 5.00
105 INT262819 Gene_expression of Serpinf1 Negative_regulation of Binding of 1190002H23Rik 1 0.05 2.66 0.43 5.00
106 INT186373 Il6 Positive_regulation of Gene_expression of Il17a 2 0.14 1.52 0.42 5.00
107 INT186385 Binding of TNF and Tnfrsf1b 4 0.30 3.24 0.42 5.00
108 INT265465 CSPG4 Negative_regulation of Gene_expression of IL8 1 0.07 0.98 0.39 5.00
109 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39 5.00
110 INT194596 Binding of HLA-DRB4 and TNFSF10 3 0.08 6 0.38 5.00
111 INT211492 Positive_regulation of GRIN1 Positive_regulation of Prkca 1 0.01 0.87 0.36 5.00
112 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34 5.00
113 INT89381 INS Positive_regulation of AKT1 6 0.43 3.06 0.33 5.00
114 INT230855 KNG1 Regulation of NOS1 2 0.03 0.94 0.33 5.00
115 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32 5.00
116 INT235971 Positive_regulation of Binding of Nqo1 and NMO-IgG 1 0.00 1.86 0.32 5.00
117 INT186345 Binding of Gast and Stat6 1 0.03 2.19 0.3 5.00
118 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3 5.00
119 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3 5.00
120 INT235957 Binding of Mog and Bcr 1 0.02 1.13 0.29 5.00
121 INT235962 Binding of Bcr and Trav6-3 1 0.00 1.12 0.29 5.00
122 INT265467 HRAS Negative_regulation of Gene_expression of PTGS2 1 0.01 0.84 0.29 5.00
123 INT235966 Binding of Mog and Trav6-3 1 0.01 1.07 0.29 5.00
124 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28 5.00
125 INT262826 Serpinf1 Negative_regulation of Gene_expression of TNF 1 0.29 1.83 0.28 5.00
126 INT282128 Gene_expression of Il10 Positive_regulation of Positive_regulation of Icam1 1 0.37 1.12 0.28 5.00
127 INT316791 Binding of HLA-DRB1 and Traf1 1 0.01 0.96 0.27 5.00
128 INT170560 Binding of Renbp and Narf 1 0.01 1.69 0.27 5.00
129 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26 5.00
130 INT206763 Binding of CSF2 and Nqo1 1 0.00 1.7 0.25 5.00
131 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24 5.00
132 INT239087 Binding of SST and Negative_regulation of Localization of GH1 1 0.19 0.36 0.24 5.00
133 INT186368 Il10 Negative_regulation of Gene_expression of Il12a 1 0.06 0.17 0.24 5.00
134 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24 5.00
135 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24 5.00
136 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24 5.00
137 INT235967 Binding of Ighm and Nqo1 1 0.00 1.45 0.23 5.00
138 INT186374 Il13 Negative_regulation of Positive_regulation of Il12a 1 0.06 0.3 0.23 5.00
139 INT186371 Il4 Negative_regulation of Positive_regulation of Il12a 1 0.06 0.3 0.23 5.00
140 INT279503 Binding of C1s and C1ra 1 0.03 0.58 0.22 5.00
141 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22 5.00
142 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22 5.00
143 INT262817 Serpinf1 Regulation of Positive_regulation of 1190002H23Rik 1 0.06 1.3 0.22 5.00
144 INT289997 CNTF Negative_regulation of Binding of CNTF and Casp3 1 0.05 0.99 0.22 5.00
145 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22 5.00
146 INT186351 Binding of Gast and Stat1 3 0.16 2.77 0.22 5.00
147 INT233929 PPARA Negative_regulation of ras 1 0.02 2.39 0.22 5.00
148 INT186391 TNF Positive_regulation of Gene_expression of Il17a 1 0.03 0.38 0.22 5.00
149 INT186358 Il1 Positive_regulation of Gene_expression of Il17a 1 0.02 0.38 0.22 5.00
150 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21 5.00
151 INT186353 Binding of Il12a and Il1 1 0.21 0.38 0.2 5.00
152 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2 5.00
153 INT175909 Binding of ROS1 and CNBP 1 0.01 1.78 0.19 5.00
154 INT175908 Binding of NOS3 and ROS1 1 0.10 1.84 0.19 5.00
155 INT279507 Serping1 Negative_regulation of Gene_expression of C3 1 0.03 1.12 0.19 5.00
156 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
157 INT279500 Serping1 Negative_regulation of Transcription of C3 1 0.03 1.12 0.19 5.00
158 INT262818 Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.45 0.71 0.18 5.00
159 INT229928 Binding of C3 and CFH 1 0.07 1.35 0.17 5.00
160 INT327789 Binding of IgG and Alms1 1 0.01 1.1 0.17 5.00
161 INT327790 Binding of Nqo1 and Alms1 1 0.00 1.1 0.17 5.00
162 INT327791 Binding of AQP4 and Alms1 1 0.03 1.1 0.17 5.00
163 INT229931 Negative_regulation of Binding of C3 and CFH 1 0.08 1.35 0.17 5.00
164 INT298641 PPARA Regulation of STAT3 1 0.23 0.98 0.16 5.00
165 INT355410 Ins1 Regulation of Gene_expression of Dbi 1 0.07 0.57 0.16 5.00
166 INT273251 Binding of IL6 and IL12A 1 0.00 1.15 0.16 5.00
167 INT251349 Ifnar1 Positive_regulation of Rock1 1 0.01 1.27 0.16 5.00
168 INT251347 Binding of Bmpr2 and Limk1 1 0.18 1.51 0.16 5.00
169 INT186380 Binding of SOAT1 and Stat6 1 0.02 0.11 0.15 5.00
170 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15 5.00
171 INT288026 PROC Positive_regulation of Gene_expression of VEGFA 1 0.01 0.5 0.15 5.00
172 INT234801 RAB3GAP1 Regulation of RAB3A 1 0.08 1.64 0.15 5.00
173 INT243524 Positive_regulation of Binding of NTF3 and SOX10 1 0.01 0.54 0.14 5.00
174 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
175 INT243525 Binding of NTF3 and SOX10 1 0.01 0.54 0.14 5.00
176 INT298639 GDE1 Negative_regulation of AKT1 1 0.00 1.14 0.14 5.00
177 INT314867 Binding of Cdc7 and Cdkn2b 1 0.25 1.16 0.14 5.00
178 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14 5.00
179 INT186357 Binding of Irf1 and Stat6 1 0.04 2.09 0.14 5.00
180 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14 5.00
181 INT186372 Binding of Irf1 and Stat1 1 0.04 2.06 0.14 5.00
182 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14 5.00
183 INT355408 Ins1 Regulation of Dbi 1 0.07 0.58 0.14 5.00
184 INT255658 Coq10a Regulation of Negative_regulation of Rgc32 1 0.01 1.14 0.14 5.00
185 INT255660 Coq10a Negative_regulation of Rgc32 1 0.02 1.11 0.13 5.00
186 INT321408 INS Positive_regulation of EGR1 1 0.03 2.36 0.13 5.00
187 INT321414 INS Positive_regulation of Transcription of EGR1 1 0.03 2.36 0.13 5.00
188 INT321404 Positive_regulation of MAP3K5 Positive_regulation of Gene_expression of SERPINE1 1 0.02 2.2 0.12 5.00
189 INT230760 VEGFA Positive_regulation of Flt1 1 0.03 0.96 0.12 5.00
190 INT321410 EGR1 Negative_regulation of Gene_expression of TNFSF10 1 0.10 2.07 0.12 5.00
191 INT340819 Regulation of Binding of Ly6g6d and Tnfrsf14 1 0.01 1.58 0.12 5.00
192 INT340818 Binding of Ly6g6d and Tnfrsf14 1 0.01 1.57 0.12 5.00
193 INT355330 Regulation of Gtf3a Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.00 0.9 0.12 5.00
194 INT186379 Il12a Positive_regulation of Binding of IFNA1 1 0.03 0.07 0.12 5.00
195 INT230761 VEGFA Positive_regulation of Kdr 2 0.02 2.16 0.12 5.00
196 INT251348 Ifnar1 Positive_regulation of Limk2 1 0.01 1.12 0.11 5.00
197 INT279511 Binding of Serping1 and C1ra 1 0.01 0.3 0.11 5.00
198 INT327792 Binding of IGFALS and Alms1 1 0.00 1.15 0.11 5.00
199 INT236467 MMP9 Negative_regulation of SNRPB 1 0.01 0.45 0.1 5.00
200 INT286418 Gtf3a Positive_regulation of Akt1 1 0.01 0.45 0.1 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Blindness. They are ordered first by their pain relevance and then by number of times they were reported in Blindness. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT205040 Gene_expression of CLTA 7 0.19 7.64 0.25 100.00
2 INT192540 Binding of CLTA 4 0.09 2.28 0.03 100.00
3 INT277526 Gene_expression of Clrn1 1 0.78 29.02 0.17 100.00
4 INT192533 Positive_regulation of CLTA 4 0.13 4.98 0.1 100.00
5 INT233921 Binding of PDR 6 0.14 7.03 0.75 100.00
6 INT139862 Negative_regulation of amd 8 0.35 10.15 0.6 100.00
7 INT229743 Negative_regulation of AOC2 2 0.42 2.03 0.21 100.00
8 INT192535 Negative_regulation of GUCY2D 2 0.41 1.38 0 99.66
9 INT164116 Negative_regulation of 1190002H23Rik 33 0.51 18.73 2.71 99.56
10 INT223153 Binding of Stat4 5 0.34 7.98 4.28 99.44
11 INT277524 Binding of Clrn1 1 0.37 1.9 0 99.40
12 INT639 Regulation of LAMC2 8 0.44 4.68 2.92 99.40
13 INT157378 Gene_expression of PDR 14 0.53 11.46 0.64 99.04
14 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35 99.04
15 INT159060 Localization of PDR 8 0.65 10.45 0.96 98.72
16 INT233922 Positive_regulation of Localization of PDR 1 0.09 2.01 0.18 98.72
17 INT233923 Regulation of Localization of PDR 1 0.08 2.04 0.18 98.72
18 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 98.62
19 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 98.52
20 INT49001 Regulation of Gria1 51 0.56 18.28 31.22 98.40
21 INT93350 Binding of Lepr 17 0.05 27.21 1.5 98.36
22 INT10373 Gene_expression of ADI1 8 0.25 5.97 0.92 98.24
23 INT346650 Gene_expression of PLK3 1 0.47 1.48 0 98.24
24 INT277539 Positive_regulation of Clrn1 1 0.50 4.04 0 98.08
25 INT19449 Binding of FANCB 22 0.47 7.4 4.27 98.00
26 INT297823 Gene_expression of Ndp 1 0.63 2.51 0 97.96
27 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 97.94
28 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 97.68
29 INT192537 Gene_expression of AIPL1 2 0.42 1.36 0 97.60
30 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 97.56
31 INT81326 Positive_regulation of Gene_expression of Ang 17 0.67 18.5 5.46 97.56
32 INT134626 Positive_regulation of Gene_expression of Kdr 20 0.63 14.63 2.29 97.56
33 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7 97.56
34 INT137271 Positive_regulation of PDE6B 4 0.29 1.95 1.53 97.16
35 INT192536 Gene_expression of PDE6B 2 0.65 1.18 0 97.16
36 INT316010 Binding of AIC 3 0.42 1.47 2.4 97.08
37 INT273160 Binding of TNMD 4 0.42 1.72 0 97.04
38 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 97.00
39 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 97.00
40 INT38173 Gene_expression of Ang 40 0.75 32.63 8.86 97.00
41 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09 97.00
42 INT342238 Negative_regulation of ARC 1 0.32 2.05 0 96.60
43 INT256900 Gene_expression of TNMD 19 0.68 7.36 0.64 96.28
44 INT234822 Positive_regulation of CHML 2 0.06 1.76 0 95.44
45 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 95.28
46 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 95.24
47 INT333339 Positive_regulation of CGF1 2 0.10 4.99 0.13 95.12
48 INT308254 Negative_regulation of Binding of PVRL1 1 0.01 1.02 0 95.08
49 INT212127 Positive_regulation of Gene_expression of Slc4a3 1 0.50 0.93 0.23 94.96
50 INT212131 Positive_regulation of Gene_expression of Cl 4 0.08 0.88 0.12 94.96
51 INT234826 Positive_regulation of Regulation of AGFG1 1 0.10 0.87 0 94.68
52 INT149125 Gene_expression of Slc4a3 25 0.78 3.45 2.41 94.60
53 INT212124 Gene_expression of Cl 18 0.11 6.72 1.93 94.60
54 INT18583 Positive_regulation of Gene_expression of Ins1 67 0.50 49.72 8.26 94.28
55 INT200435 Binding of polymerase 6 0.16 5.56 0.47 94.28
56 INT185394 Binding of PVRL1 5 0.14 2.94 0.09 94.28
57 INT91070 Regulation of GSR 27 0.59 16.64 3.42 94.24
58 INT10874 Negative_regulation of Twist1 89 0.50 36.84 11.32 94.08
59 INT260525 Gene_expression of AMD1 25 0.66 24.58 1.32 94.00
60 INT201261 Regulation of AGFG1 4 0.09 2.72 0.9 93.92
61 INT139863 Binding of amd 27 0.41 41.3 0.91 93.60
62 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 93.60
63 INT314825 Gene_expression of Atoh7 1 0.71 1.46 0 93.48
64 INT314843 Positive_regulation of Gene_expression of Atoh7 1 0.63 0.27 0 93.48
65 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 93.28
66 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37 93.00
67 INT49930 Binding of Ighg1 21 0.37 13.27 2.43 92.56
68 INT310679 Positive_regulation of ARSB 1 0.39 2.36 0.04 92.44
69 INT256397 Binding of Nefh 3 0.09 1.31 0 92.40
70 INT129771 Regulation of SMARCB1 5 0.58 8.92 0.58 92.36
71 INT39856 Binding of Neurod1 8 0.47 1.44 2.88 92.36
72 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 92.12
73 INT310681 Negative_regulation of ARSB 1 0.56 6.95 0.29 91.72
74 INT247868 Positive_regulation of Narfl 1 0.11 37.11 0.68 91.52
75 INT310683 Protein_catabolism of ARSB 1 0.73 1.85 0.04 91.40
76 INT8637 Negative_regulation of Dbp 112 0.50 33.28 8.4 91.32
77 INT289494 Regulation of 1190002H23Rik 1 0.04 1.64 0 90.92
78 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 90.52
79 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 90.36
80 INT39376 Positive_regulation of HK1 6 0.53 2.44 1.49 90.16
81 INT7580 Positive_regulation of Mbp 54 0.70 23.37 17.14 90.08
82 INT160505 Gene_expression of Ctsd 1 0.73 2.57 0.15 90.00
83 INT163461 Regulation of ABL1 8 0.32 5.98 0.14 90.00
84 INT310678 Protein_catabolism of ARSH 1 0.06 1.76 0.04 89.76
85 INT38963 Binding of Lsd 7 0.41 1.91 4.12 89.72
86 INT294407 Positive_regulation of Negative_regulation of Vav3 1 0.50 0.73 0 89.64
87 INT294406 Positive_regulation of Negative_regulation of Vav2 1 0.50 0.73 0 89.64
88 INT294399 Negative_regulation of Vav3 1 0.59 1.59 0 89.64
89 INT294405 Negative_regulation of Vav2 1 0.59 1.58 0 89.64
90 INT24443 Gene_expression of PSMD2 20 0.54 7.29 2.77 89.44
91 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3 89.12
92 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 88.96
93 INT105761 Binding of GFAP 13 0.36 14.94 2.32 88.88
94 INT277550 Positive_regulation of Gm14374 2 0.49 1.5 0.42 88.68
95 INT277532 Positive_regulation of Positive_regulation of Clrn1 1 0.50 1.44 0 88.68
96 INT277535 Positive_regulation of Positive_regulation of Gm14374 1 0.49 1.44 0 88.68
97 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 88.56
98 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12 88.52
99 INT88810 Positive_regulation of Gene_expression of FGF2 17 0.50 12.62 2.98 88.52
100 INT256902 Positive_regulation of TNMD 3 0.44 5.27 0.13 88.40
101 INT185649 Regulation of ERG 17 0.20 10.14 1.49 88.32
102 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37 88.24
103 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 87.92
104 INT314840 Regulation of Gene_expression of Atoh7 1 0.41 0.26 0 87.80
105 INT10303 Regulation of STH 16 0.60 16.14 0.95 87.76
106 INT297836 Negative_regulation of Ndp 1 0.41 1.8 0 87.76
107 INT52347 Negative_regulation of CHM 17 0.58 13.03 0.59 87.72
108 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 87.32
109 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 87.20
110 INT316787 Binding of Ptpn22 1 0.29 3.61 1.29 87.20
111 INT102891 Positive_regulation of AGTR1 31 0.67 30.57 5.29 87.16
112 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92 87.08
113 INT21660 Regulation of CHM 14 0.61 8.51 0.93 87.08
114 INT234816 Phosphorylation of CHM 1 0.04 0.79 0 86.88
115 INT233908 Protein_catabolism of amd 1 0.08 1.73 0.04 86.80
116 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 86.80
117 INT36799 Negative_regulation of Ighm 21 0.41 17.47 3.65 86.80
118 INT47094 Negative_regulation of Ctsd 2 0.56 2.54 0.41 86.80
119 INT316027 Regulation of Binding of AIC 1 0.39 0.09 0.03 86.72
120 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 86.44
121 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 86.44
122 INT10131 Gene_expression of Serpinf1 53 0.76 35.57 6.42 86.32
123 INT52924 Negative_regulation of GSR 49 0.58 28.08 9.28 86.00
124 INT1922 Positive_regulation of CEACAM7 32 0.70 33.31 2.72 85.92
125 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 85.76
126 INT346642 Positive_regulation of Positive_regulation of TNMD 1 0.44 1.28 0 85.68
127 INT140411 Gene_expression of Nqo1 45 0.60 62.35 8.7 85.68
128 INT22797 Regulation of Regulation of Shbg 2 0.32 0.75 0.18 85.48
129 INT234815 Phosphorylation of RAB27A 1 0.37 0.77 0 85.40
130 INT17349 Negative_regulation of Akr1b1 41 0.59 27.03 10.65 85.32
131 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 85.28
132 INT57147 Binding of ANIB1 3 0.31 1.65 0.44 85.28
133 INT277537 Transcription of Clrn1 1 0.72 5.06 0 85.12
134 INT206760 Localization of Nqo1 8 0.09 15.76 2.4 85.12
135 INT182647 Positive_regulation of EPB41 2 0.01 0.77 0.2 85.12
136 INT22798 Regulation of Shbg 64 0.60 26.71 8.76 85.08
137 INT138694 Negative_regulation of NINL 1 0.38 0.97 0.48 85.08
138 INT17741 Gene_expression of MBP 67 0.78 23.67 9.65 85.04
139 INT242921 Positive_regulation of Aoc2-ps1 1 0.12 1.82 0.04 85.04
140 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 85.04
141 INT297804 Regulation of Lrp5 6 0.60 2.31 0.27 84.84
142 INT297821 Regulation of Fzd4 1 0.03 0.57 0 84.84
143 INT297820 Regulation of Transcription of Lrp5 2 0.44 0.83 0 84.84
144 INT192951 Negative_regulation of AES 15 0.38 6.38 3.5 84.80
145 INT277542 Negative_regulation of Pdc 1 0.03 1.61 0 84.76
146 INT47714 Regulation of Nqo1 12 0.24 11.12 1.71 84.56
147 INT18322 Negative_regulation of Ins1 132 0.58 88.49 22.59 84.48
148 INT297791 Transcription of Fzd4 1 0.06 0.58 0 84.40
149 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 84.08
150 INT170033 Positive_regulation of Gene_expression of Fig4 59 0.43 20.99 16.69 84.08
151 INT297757 Transcription of Lrp5 2 0.68 0.82 0 83.84
152 INT20055 Gene_expression of CRTAC1 19 0.58 15.49 4.73 83.36
153 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 83.20
154 INT173419 Gene_expression of Ddit3 16 0.75 23.31 1.87 83.20
155 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51 83.20
156 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 83.12
157 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56 82.92
158 INT109881 Positive_regulation of Gene_expression of F8 11 0.47 12.97 1.54 82.92
159 INT203443 Gene_expression of Isl1 27 0.67 11.12 4.65 82.84
160 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 82.80
161 INT871 Negative_regulation of Gene_expression of Prl 53 0.58 18.89 17.79 82.80
162 INT251332 Negative_regulation of Limk1 1 0.59 16.43 4.66 82.76
163 INT268903 Protein_catabolism of Sln 5 0.75 0.83 0.2 82.56
164 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 82.36
165 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 82.32
166 INT64454 Positive_regulation of Ctsd 2 0.44 1.14 0.57 82.32
167 INT223459 Gene_expression of Dock4 2 0.71 1.5 0.16 82.16
168 INT286390 Gene_expression of Cdc42ep5 1 0.02 0.82 0 82.16
169 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 82.12
170 INT7465 Negative_regulation of Mbp 53 0.58 19.12 13.27 82.08
171 INT812 Localization of INS 1026 0.81 515.6 145.31 82.00
172 INT2296 Positive_regulation of Gene_expression of Prl 137 0.70 36.96 35.39 81.92
173 INT213648 Phosphorylation of S100A6 2 0.30 1.43 0.36 81.80
174 INT27309 Negative_regulation of Negative_regulation of Mbp 2 0.57 0.3 0.09 81.68
175 INT223746 Binding of Il10 12 0.36 9.49 1.73 81.52
176 INT172964 Binding of Vegfa 14 0.47 10.62 0.53 81.52
177 INT76584 Gene_expression of GCA 1 0.58 1.29 0.24 81.36
178 INT268715 Binding of RPE 3 0.09 2.36 0.09 81.28
179 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05 81.24
180 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 80.96
181 INT218247 Gene_expression of Cardf1 3 0.65 2.37 0.24 80.92
182 INT10132 Negative_regulation of Serpinf1 14 0.58 11.72 3.14 80.88
183 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 80.80
184 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 80.76
185 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 80.76
186 INT260527 Negative_regulation of AMD1 6 0.37 5 0.05 80.68
187 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 80.60
188 INT165342 Gene_expression of TGFBI 13 0.59 5.81 0.39 80.44
189 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 80.40
190 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 80.24
191 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63 79.88
192 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 79.60
193 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 79.52
194 INT64538 Binding of TNNI3 17 0.48 11.65 1.83 79.52
195 INT153492 Gene_expression of Gmcl1 44 0.65 15.77 2.56 79.28
196 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 78.96
197 INT215923 Positive_regulation of Mog 8 0.19 9.86 3.17 78.80
198 INT228376 Binding of Tlr3 2 0.45 2.2 0.07 78.72
199 INT287528 Gene_expression of WFS1 1 0.75 2.74 1.55 78.24
200 INT61316 Gene_expression of Coq10a 59 0.73 32.81 3.95 78.20
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