D:Blister

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Disease Term
Synonyms Bleb, BLEBS, Blisters, BULLA, Bullae, Bullous Lesion, BULLOUS LESIONS, Lesion Bullous, LESIONS BULLOUS, Vesication, Vesications
Documents 1194
Hot Single Events 200
Hot Interactions 18

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Blister. They are ordered first by their relevance to Blister and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT320769 Atp11c Regulation of Dsg1a 1 0.05 5.87 0 99.40
2 INT234988 Negative_regulation of Binding of Dsg3 and IgG 1 0.04 0.83 0 96.44
3 INT234967 Binding of Dsg3 and IgG 1 0.03 0.83 0 96.44
4 INT337917 Binding of sb and Tgfbr1 1 0.00 1.06 0 96.16
5 INT320770 Dsg2 Positive_regulation of Stat3 1 0.28 0.74 0.13 94.72
6 INT320765 Dsg2 Positive_regulation of Akt1 1 0.48 0.74 0.13 93.44
7 INT275123 Binding of HLA-E and SUGT1 1 0.00 0.93 0 91.36
8 INT236467 MMP9 Negative_regulation of SNRPB 1 0.01 0.45 0.1 87.68
9 INT235000 IgG Negative_regulation of DSG1 1 0.04 0.86 0 86.88
10 INT235016 IgG Negative_regulation of Binding of DSG1 1 0.04 2.89 0 86.88
11 INT235008 Binding of DSG1 and Dsg3 1 0.11 4.82 0 85.16
12 INT282684 FECH Positive_regulation of Negative_regulation of Ssbp3 1 0.00 1.54 0.08 85.04
13 INT334770 Ednra Positive_regulation of Pla2g4a 1 0.00 0.24 0.14 85.00
14 INT334765 Ednra Positive_regulation of Positive_regulation of Car2 1 0.02 0.24 0.14 85.00
15 INT334772 Ednra Positive_regulation of Ednra Positive_regulation of Pla2g4a 1 0.00 0.24 0.14 85.00
16 INT41617 Sp5 Positive_regulation of Mlf1 1 0.02 0.25 0.94 84.16
17 INT320767 Atp11c Negative_regulation of Dsg1a 1 0.05 1.71 0 82.92
18 INT320766 Spp1 Negative_regulation of Dsg1a 1 0.11 1.05 0 82.04
19 INT354789 Tnc Regulation of HSPG2 1 0.02 1.38 0 78.72
20 INT241739 Sdhb Regulation of Adora2b 1 0.04 0.63 0.31 78.68
21 INT337915 Tgfbr1 Positive_regulation of Negative_regulation of Smad2 1 0.05 0.15 0 78.24
22 INT337918 sb Positive_regulation of Negative_regulation of Smad2 1 0.00 0.15 0 78.24
23 INT232906 Binding of KRT1 and KRT10 1 0.18 0.51 0 77.56
24 INT235002 Negative_regulation of Binding of DSG1 and Dsg3 1 0.13 1.08 0 75.52
25 INT320771 Atp11c Regulation of Localization of Dsg1a 1 0.03 1.46 0 74.28
26 INT194578 Binding of HOXA10 and BTG3 1 0.00 0.66 0.24 73.68
27 INT34823 Regulation of Binding of Ldha and Akr7a3 1 0.43 0.28 0.72 68.88
28 INT34824 Binding of Ldha and Akr7a3 1 0.36 0.28 0.71 67.60
29 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95 67.44
30 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13 66.80
31 INT337916 sb Negative_regulation of Ctgf 1 0.00 0.13 0 63.08
32 INT337914 sb Negative_regulation of Phosphorylation of Smad2 1 0.00 0.13 0 63.08
33 INT234972 IgG Positive_regulation of Gene_expression of Dsg3 1 0.05 0.8 0 56.92
34 INT234999 IgG Positive_regulation of Gene_expression of DSG1 1 0.05 0.8 0 56.92
35 INT34825 Aap Negative_regulation of Gsr 1 0.01 0.3 0.75 56.32
36 INT320768 Spp1 Regulation of Protein_catabolism of Dsg1a 1 0.08 0.77 0.11 50.00
37 INT234985 Binding of Dsg3 and Pitx3 1 0.00 0.3 0 42.16
38 INT267631 IRF6 Positive_regulation of Gene_expression of Il1 1 0.00 0.96 0.25 37.92
39 INT314263 Binding of CPOX and PTGES3 1 0.01 1.7 0.44 36.92
40 INT314267 Binding of CPOX and PTGES 1 0.03 0.34 0.09 36.92
41 INT314269 Binding of PTGES and PTGES3 1 0.12 0.68 0.18 36.36
42 INT354833 Csf2 Positive_regulation of Cd8a 1 0.01 0.98 0 32.08
43 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88 27.72
44 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56 10.56
45 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
46 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4 5.00
47 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
48 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 5.00
49 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
50 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54 5.00
51 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
52 INT116892 Binding of TRPV1 and Phax 4 0.00 0.1 1.24 5.00
53 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14 5.00
54 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13 5.00
55 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11 5.00
56 INT308173 Binding of DRG1 and Tnfrsf1b 1 0.01 1.64 1.1 5.00
57 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1 5.00
58 INT266742 GOPC Regulation of Positive_regulation of ACR 1 0.02 0.36 1.05 5.00
59 INT201614 Mc1r Regulation of Uvbi1 1 0.04 1.42 0.98 5.00
60 INT93306 Binding of TRPV1 and CAP1 2 0.18 0.07 0.97 5.00
61 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75 5.00
62 INT267630 Il1 Regulation of Gene_expression of IL8 1 0.00 0.44 0.71 5.00
63 INT308167 Binding of Eln and Tnfrsf1b 1 0.01 0.94 0.71 5.00
64 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 5.00
65 INT110835 Binding of SPTLC2 and SPTLC1 2 0.42 1.36 0.68 5.00
66 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61 5.00
67 INT267625 Binding of KNG1 and Klk1 2 0.21 2.23 0.61 5.00
68 INT171905 TNF Positive_regulation of Gene_expression of Il1 2 0.23 1.08 0.54 5.00
69 INT216918 Binding of Ca2 and Abat 1 0.01 0.45 0.53 5.00
70 INT216919 Ngf Positive_regulation of Gene_expression of P2rx3 1 0.18 0.69 0.53 5.00
71 INT354986 Cacna1a Regulation of Localization of Mpo 1 0.01 1.15 0.49 5.00
72 INT308170 Binding of thd and Tnfrsf14 1 0.00 1.84 0.46 5.00
73 INT194577 Binding of BTG3 and BDNF-AS 1 0.01 0.31 0.46 5.00
74 INT308171 Binding of TNF and thd 1 0.00 1.84 0.45 5.00
75 INT354981 Cacna1a Negative_regulation of Gene_expression of Nos2 1 0.01 0.99 0.45 5.00
76 INT201610 Binding of Mc1r and Braf 1 0.31 0.75 0.42 5.00
77 INT334763 Ednra Positive_regulation of Gabrg1 1 0.01 0 0.4 5.00
78 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4 5.00
79 INT256321 INCENP Positive_regulation of Gene_expression of Vcam1 1 0.00 1.89 0.38 5.00
80 INT355018 Binding of FAS and Faslg 1 0.12 1.34 0.37 5.00
81 INT267585 TNF Regulation of IL6 2 0.16 2.44 0.37 5.00
82 INT267595 IL12A Positive_regulation of IFN1@ 1 0.03 0.69 0.36 5.00
83 INT110834 Binding of AGXT and SPTLC2 2 0.27 0.71 0.36 5.00
84 INT354985 Cacna1a Regulation of Nos2 1 0.01 0.73 0.34 5.00
85 INT354982 Cacna1a Regulation of Tnf 1 0.00 0.73 0.34 5.00
86 INT267589 IL2 Positive_regulation of Gene_expression of IL12A 1 0.01 0.69 0.34 5.00
87 INT241742 Negative_regulation of Sdhb Regulation of Rapgef5 1 0.02 0.39 0.33 5.00
88 INT241740 Sdhb Regulation of Rapgef5 1 0.02 0.34 0.32 5.00
89 INT203169 CPOX Regulation of Gene_expression of PTGER2 2 0.00 0.48 0.29 5.00
90 INT267628 IL4 Positive_regulation of IgG 1 0.00 1.42 0.27 5.00
91 INT229785 Binding of RAB7A and SPTLC1 1 0.40 1.5 0.27 5.00
92 INT267586 IL4 Positive_regulation of IGHE 1 0.00 1.42 0.27 5.00
93 INT245920 Binding of GLA and TRPV1 1 0.09 0.36 0.26 5.00
94 INT245926 Binding of ABCC1 and TRPV1 1 0.17 0.36 0.26 5.00
95 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26 5.00
96 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26 5.00
97 INT267632 Il1 Positive_regulation of Gene_expression of PLA2G6 1 0.00 0.86 0.25 5.00
98 INT267624 Klk1 Positive_regulation of KNG1 1 0.05 0.52 0.25 5.00
99 INT267584 TNF Positive_regulation of Gene_expression of PLA2G6 1 0.08 0.87 0.25 5.00
100 INT267596 KNG1 Positive_regulation of Gene_expression of PLA2G6 1 0.01 0.87 0.25 5.00
101 INT267591 CYSLTR1 Positive_regulation of Gene_expression of PLA2G6 1 0.00 0.87 0.25 5.00
102 INT188842 Accn3 Positive_regulation of Calca 1 0.08 0.46 0.25 5.00
103 INT321653 Binding of Phc1 and Datd 1 0.00 0.35 0.24 5.00
104 INT267623 IL6 Positive_regulation of Crp 1 0.00 1.6 0.24 5.00
105 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2 5.00
106 INT235014 Car2 Positive_regulation of DSP 1 0.06 0.28 0.2 5.00
107 INT314273 Uvbi1 Positive_regulation of Gene_expression of PTGER2 1 0.00 0.45 0.19 5.00
108 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
109 INT267629 PTAFR Positive_regulation of Localization of Il1 1 0.00 1.32 0.18 5.00
110 INT190381 IL1A Regulation of Transcription of DEFB4A 1 0.06 0.93 0.18 5.00
111 INT198700 Binding of DSG3 and Pv 1 0.15 1.45 0.18 5.00
112 INT334769 Ednra Positive_regulation of Car2 1 0.02 0.49 0.18 5.00
113 INT267627 Il1 Positive_regulation of Gene_expression of TNF 1 0.02 0.45 0.17 5.00
114 INT201609 Uvbi1 Positive_regulation of Gene_expression of Mc1r 1 0.05 0.57 0.17 5.00
115 INT314270 CPOX Negative_regulation of Gene_expression of PTGER2 1 0.01 0.15 0.17 5.00
116 INT201608 Binding of Mc1r and Uvbi1 1 0.03 0.93 0.15 5.00
117 INT201622 Binding of Mark3 and Mc1r 1 0.33 0.74 0.15 5.00
118 INT198307 IL10 Positive_regulation of Gene_expression of IGHG3 2 0.01 1.21 0.15 5.00
119 INT201619 Binding of Cdk11b and Mc1r 1 0.28 0.74 0.15 5.00
120 INT194576 Binding of ACLY and CD40LG 1 0.07 0.07 0.14 5.00
121 INT256320 Binding of CYP26A1 and Hapln1 1 0.01 1.27 0.14 5.00
122 INT334759 Ednra Regulation of Gabrg1 1 0.01 0 0.13 5.00
123 INT243557 Binding of PSPH and SPECC1 1 0.01 1.19 0.12 5.00
124 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11 5.00
125 INT355023 Phosphorylation of Rtn4r Negative_regulation of Binding of Mag and Rtn4r 1 0.00 0.38 0.11 5.00
126 INT334761 Binding of Ednra and Gopc 1 0.03 0 0.11 5.00
127 INT190382 IL1A Regulation of Regulation of DEFB4A 1 0.06 0.57 0.1 5.00
128 INT245918 MRPS7 Negative_regulation of TRPV1 1 0.41 0.06 0.1 5.00
129 INT245952 Phax Negative_regulation of TRPV1 1 0.00 0.06 0.1 5.00
130 INT245927 CAP1 Negative_regulation of TRPV1 1 0.02 0.06 0.1 5.00
131 INT355008 Binding of Mag and Rtn4r 1 0.02 0.36 0.1 5.00
132 INT267587 PTAFR Positive_regulation of Localization of PTPRC 1 0.00 2.04 0.09 5.00
133 INT333095 Localization of IL2 Negative_regulation of Negative_regulation of CD8A 1 0.10 0.8 0.09 5.00
134 INT341054 Binding of PAEP and RAB14 1 0.00 0.28 0.09 5.00
135 INT333099 Localization of IL2 Negative_regulation of Negative_regulation of CD4 1 0.14 0.8 0.09 5.00
136 INT267626 Il1 Positive_regulation of ICAM1 1 0.00 0.79 0.09 5.00
137 INT245951 Binding of FIBP and Phax 1 0.00 0 0.09 5.00
138 INT333094 HIVEP1 Regulation of CD4 1 0.00 0.22 0.09 5.00
139 INT245921 Binding of FIBP and CAP1 1 0.00 0 0.09 5.00
140 INT201618 Uvbi1 Positive_regulation of Phb 1 0.04 0.28 0.09 5.00
141 INT333121 Pol Positive_regulation of CD8A 1 0.00 0.08 0.09 5.00
142 INT181845 Binding of CD8A and IFN1@ 2 0.13 0.65 0.09 5.00
143 INT267618 Il1 Positive_regulation of Vcam1 1 0.00 0.81 0.09 5.00
144 INT314264 Negative_regulation of CPOX Negative_regulation of Gene_expression of PTGER2 1 0.01 0.15 0.09 5.00
145 INT333089 CD4 Positive_regulation of ERVW-1 1 0.05 0.07 0.08 5.00
146 INT305257 Obsty1 Regulation of Gene_expression of Mapk1 1 0.03 2.05 0.08 5.00
147 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08 5.00
148 INT355021 Cntf Positive_regulation of SOAT1 1 0.02 0.7 0.08 5.00
149 INT201615 Binding of Mark3 and Uvbi1 1 0.03 0.36 0.08 5.00
150 INT333097 ERVW-1 Positive_regulation of CD8A 1 0.02 0.08 0.08 5.00
151 INT355022 Cntf Positive_regulation of JAK1 1 0.00 0.69 0.08 5.00
152 INT314265 PTGER2 Positive_regulation of Gene_expression of PTGES2 1 0.00 0.19 0.08 5.00
153 INT305274 Obsty1 Regulation of Gene_expression of Prkag1 1 0.01 0.94 0.08 5.00
154 INT201621 Binding of Cdk11b and Uvbi1 1 0.02 0.36 0.08 5.00
155 INT201616 Uvbi1 Positive_regulation of Mark3 1 0.03 0.36 0.08 5.00
156 INT241741 Sdhb Positive_regulation of Transcription of Adora2b 1 0.07 0.28 0.08 5.00
157 INT201611 Uvbi1 Negative_regulation of Bop1 1 0.03 0.3 0.08 5.00
158 INT201613 Uvbi1 Positive_regulation of Cdk11b 1 0.03 0.36 0.08 5.00
159 INT355009 Cntf Positive_regulation of Il6st 1 0.02 0.69 0.08 5.00
160 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08 5.00
161 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08 5.00
162 INT232917 Binding of KRT8 and KRT19 2 0.16 1.04 0.08 5.00
163 INT352357 CPZ Positive_regulation of Gene_expression of HLA-DRA 1 0.12 0.13 0.07 5.00
164 INT352358 CD86 Positive_regulation of GOPC 1 0.30 0.13 0.07 5.00
165 INT267592 IL6 Positive_regulation of Localization of MUC1 1 0.00 1.24 0.07 5.00
166 INT333096 Binding of CD4 and IFN1@ 1 0.12 0.17 0.07 5.00
167 INT221878 Binding of Ltp and Ctrcts 1 0.00 1.94 0.07 5.00
168 INT333092 Binding of CD4 and IL2 1 0.01 0.17 0.07 5.00
169 INT333098 Binding of CD8A and IL2 1 0.01 0.17 0.07 5.00
170 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06 5.00
171 INT245919 Binding of TRPV1 and MRPS7 1 0.47 0 0.06 5.00
172 INT314274 Uvbi1 Regulation of Gene_expression of PTGER2 1 0.00 0.18 0.06 5.00
173 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06 5.00
174 INT344254 Binding of PARP1 and CASP3 1 0.06 0.94 0.06 5.00
175 INT267593 IL8 Positive_regulation of Localization of MUC1 1 0.00 1.06 0.06 5.00
176 INT333091 Localization of IFN1@ Negative_regulation of Negative_regulation of CD4 1 0.14 0.4 0.05 5.00
177 INT235006 IgG Positive_regulation of SRC 1 0.01 0.82 0.05 5.00
178 INT275126 Binding of CSTB and IGHG3 1 0.00 0.49 0.05 5.00
179 INT235010 Positive_regulation of Positive_regulation of SRC 1 0.01 0.84 0.05 5.00
180 INT236466 SNRPB Positive_regulation of NFKB2 1 0.00 0.21 0.05 5.00
181 INT321651 Binding of Slc6a3 and Uts2r 1 0.04 0.06 0.05 5.00
182 INT232914 Binding of KRT2 and KRT7 1 0.15 0.63 0.05 5.00
183 INT232916 Binding of KRT2 and KRT19 1 0.21 0.62 0.05 5.00
184 INT232907 Binding of KRT7 and KRT8 1 0.09 0.63 0.05 5.00
185 INT284705 CMA1 Positive_regulation of Gene_expression of COL7A1 1 0.04 0.49 0.05 5.00
186 INT321652 Binding of Slc6a3 and Slc6a4 1 0.26 0.07 0.05 5.00
187 INT333090 Localization of IFN1@ Negative_regulation of Negative_regulation of CD8A 1 0.10 0.4 0.05 5.00
188 INT321654 Binding of Slc6a4 and Uts2r 1 0.05 0.07 0.05 5.00
189 INT234990 Binding of Cish and Dsp 1 0.01 0.24 0.04 5.00
190 INT235003 Binding of NKS1 and Rdh2 1 0.00 0.18 0.04 5.00
191 INT354983 Cacna1a Regulation of Mpo 1 0.02 0.41 0.04 5.00
192 INT234986 Binding of Rdh2 and Dsp 1 0.00 0.24 0.04 5.00
193 INT275125 Binding of HLA-DOA and HSPG2 1 0.01 1.42 0.04 5.00
194 INT341055 Binding of HRC and RAB14 1 0.00 0 0.04 5.00
195 INT234994 Binding of NKS1 and Dsg3 1 0.00 0.5 0.04 5.00
196 INT235012 Binding of NKS1 and Dsp 1 0.00 0.24 0.04 5.00
197 INT275124 Binding of HSPG2 and LTA 1 0.12 1.45 0.04 5.00
198 INT234998 Binding of NKS1 and Cish 1 0.00 0.18 0.04 5.00
199 INT234991 Binding of Dsg3 and Positive_regulation of Pik3r1 1 0.05 0.32 0.03 5.00
200 INT354987 Cacna1a Regulation of Localization of LDHA 1 0.00 0.23 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Blister. They are ordered first by their pain relevance and then by number of times they were reported in Blister. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 100.00
2 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 100.00
3 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 100.00
4 INT320748 Positive_regulation of Protein_catabolism of Dsg1a 1 0.50 1.55 0 100.00
5 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 100.00
6 INT174100 Gene_expression of YWHAE 14 0.31 12.42 0.08 100.00
7 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55 100.00
8 INT39414 Gene_expression of SNRPB 37 0.59 14.07 2.52 99.96
9 INT320761 Protein_catabolism of Dsg1a 1 1.00 6.9 0.11 99.92
10 INT4340 Positive_regulation of Localization of Ldha 46 0.70 14.52 15.66 99.88
11 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71 99.84
12 INT250395 Gene_expression of GNLY 5 0.31 1.96 0.07 99.74
13 INT354786 Positive_regulation of Gene_expression of GNLY 1 0.01 1.96 0 99.74
14 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55 99.72
15 INT68695 Gene_expression of HTT 63 0.77 44.54 3.69 99.68
16 INT65640 Positive_regulation of Localization of Edn1 2 0.42 2.16 1.48 99.68
17 INT6361 Localization of Edn1 30 0.81 19.09 9.7 99.68
18 INT123142 Gene_expression of DEFB4A 54 0.76 36.14 10.02 99.64
19 INT39413 Negative_regulation of SNRPB 7 0.31 2.57 2.36 99.60
20 INT39412 Negative_regulation of Gene_expression of SNRPB 2 0.14 0.95 0.27 99.60
21 INT15092 Positive_regulation of SLC6A4 17 0.67 7.32 6.7 99.58
22 INT168304 Positive_regulation of SNRPB 17 0.25 9.62 1.64 99.56
23 INT236480 Positive_regulation of Gene_expression of SNRPB 2 0.13 0.79 0.1 99.56
24 INT1416 Transcription of POMC 40 0.72 10.71 15.38 99.52
25 INT60527 Transcription of IL10 16 0.56 13.57 6.42 99.52
26 INT250402 Positive_regulation of GNLY 2 0.20 1.95 0 99.48
27 INT195080 Positive_regulation of Tnc 4 0.45 26.67 2.34 99.44
28 INT136791 Negative_regulation of Spp1 24 0.59 23.6 3.33 99.44
29 INT284709 Negative_regulation of CMA1 9 0.57 7.06 0.21 99.40
30 INT234888 Binding of Dsg2 9 0.34 11.73 0.11 99.40
31 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 99.38
32 INT3920 Localization of Ldha 241 0.81 83.08 58.72 99.34
33 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 99.28
34 INT246315 Localization of Ednra 22 0.15 2.73 4.64 99.26
35 INT234933 Gene_expression of Dsg2 3 0.71 38.52 0.2 99.24
36 INT320739 Positive_regulation of Gene_expression of Dsg2 1 0.63 8.03 0 99.24
37 INT313785 Gene_expression of Dsg1a 3 0.78 18.92 0 99.12
38 INT27114 Gene_expression of Atp11c 20 0.42 22.22 2.37 99.12
39 INT71437 Positive_regulation of Gene_expression of Atp11c 2 0.27 5.63 0.16 99.12
40 INT36678 Binding of TIMP1 33 0.36 14.99 7.87 99.12
41 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.12
42 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 98.96
43 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 98.92
44 INT46221 Positive_regulation of Gene_expression of IgG 46 0.53 33.66 7.7 98.92
45 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 98.92
46 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 98.92
47 INT80656 Regulation of SLC17A5 15 0.26 6.89 3.19 98.92
48 INT188326 Regulation of ALK 1 0.01 1.03 0.11 98.92
49 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 98.88
50 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 98.88
51 INT176516 Localization of Spp1 28 0.76 19.39 1.9 98.84
52 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 98.80
53 INT64777 Negative_regulation of COL5A2 32 0.38 17.4 2.28 98.80
54 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 98.76
55 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 98.76
56 INT211095 Negative_regulation of Dag1 14 0.57 7.18 1.07 98.72
57 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 98.68
58 INT320749 Regulation of Localization of Dsg1a 1 0.45 2.53 0 98.68
59 INT320758 Localization of Dsg1a 1 0.80 4.07 0 98.68
60 INT272275 Regulation of Positive_regulation of NARFL 8 0.36 16.68 0.86 98.68
61 INT320747 Negative_regulation of Binding of Dsg1a 1 0.43 1.36 0 98.66
62 INT320743 Negative_regulation of Gene_expression of Dsg2 1 0.39 3.95 0 98.64
63 INT209354 Gene_expression of SLC9A6 15 0.58 37.52 0.29 98.62
64 INT234857 Gene_expression of Dsg3 42 0.78 27.75 0.14 98.60
65 INT140647 Gene_expression of DSG1 45 0.75 27.95 1.33 98.60
66 INT236475 Localization of SNRPB 1 0.04 2.85 0.13 98.54
67 INT250396 Localization of GNLY 2 0.68 1.91 0.03 98.54
68 INT170444 Binding of Gopc 172 0.39 45.05 20.71 98.54
69 INT320746 Binding of Dsg1a 1 0.48 6.43 0 98.44
70 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 98.32
71 INT39221 Gene_expression of Akr7a3 2 0.57 0.38 0.23 98.32
72 INT20455 Positive_regulation of Bche 15 0.59 7.22 3.7 98.16
73 INT32852 Negative_regulation of FECH 18 0.57 10.59 3.08 98.06
74 INT68693 Regulation of Gene_expression of HTT 3 0.45 0.72 0.06 98.04
75 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 98.00
76 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 97.92
77 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 97.92
78 INT98607 Regulation of Regulation of TNF 8 0.44 6.95 2.56 97.84
79 INT9660 Regulation of TNF 363 0.62 312.94 139.99 97.84
80 INT8691 Localization of Insr 85 0.80 9.27 30.32 97.84
81 INT23527 Negative_regulation of Localization of Insr 10 0.39 2.58 2.5 97.84
82 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 97.84
83 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 97.76
84 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 97.72
85 INT70027 Positive_regulation of Gene_expression of C6orf25 10 0.62 7.21 0.83 97.72
86 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 97.68
87 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 97.64
88 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06 97.56
89 INT78190 Gene_expression of Tnc 10 0.75 21.23 2.91 97.56
90 INT71305 Regulation of Gene_expression of NFKB1 9 0.61 5.41 2.44 97.48
91 INT53020 Positive_regulation of ACSM3 9 0.58 11.03 2.73 97.32
92 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33 97.20
93 INT9210 Regulation of IL6 166 0.62 125.61 49.95 97.20
94 INT24893 Phosphorylation of CSF2 3 0.74 2.75 0.28 97.20
95 INT234909 Phosphorylation of Dnajc27 1 0.01 1.47 0.11 97.20
96 INT55170 Gene_expression of NFKB1 97 0.77 52.75 23.04 97.18
97 INT98697 Regulation of Dsg1a 2 0.45 7.33 0 97.16
98 INT98696 Regulation of Dsg3 4 0.45 5.45 0 97.16
99 INT98132 Regulation of FAS 16 0.42 20.57 2.06 97.08
100 INT12772 Positive_regulation of Positive_regulation of IKBKG 9 0.69 0.84 4.12 97.00
101 INT133768 Regulation of Fasl 10 0.44 10.24 3.32 96.92
102 INT354783 Positive_regulation of Regulation of Fasl 1 0.20 1.49 0.05 96.92
103 INT12771 Positive_regulation of IKBKG 27 0.69 5.99 7.02 96.72
104 INT9191 Localization of EDN1 94 0.81 57.01 14.78 96.64
105 INT193939 Binding of PSEN1 10 0.36 6.16 1.93 96.64
106 INT187628 Gene_expression of KRT14 15 0.75 11.54 0.1 96.56
107 INT234919 Negative_regulation of Dsg2 5 0.39 6.76 0.04 96.52
108 INT53493 Negative_regulation of C6 3 0.53 2.68 1.77 96.48
109 INT20205 Binding of IgG 108 0.46 66.68 8.57 96.44
110 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47 96.32
111 INT167049 Binding of Ednra 3 0.07 3.47 6.84 96.24
112 INT265316 Binding of Tgfbr1 2 0.35 0.59 0 96.16
113 INT333108 Transcription of AD5 1 0.04 0.34 0.15 96.16
114 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 96.08
115 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 96.08
116 INT176510 Binding of Spp1 21 0.42 22.1 2 96.04
117 INT258619 Transcription of Acta1 1 0.06 0.48 0 96.04
118 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 95.96
119 INT320755 Positive_regulation of Negative_regulation of Dsg1a 1 0.50 1.23 0 95.80
120 INT68694 Positive_regulation of Gene_expression of HTT 7 0.49 4.29 0.29 95.76
121 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 95.68
122 INT213750 Positive_regulation of NHS 14 0.59 2.17 1.43 95.60
123 INT320751 Negative_regulation of Dsg1a 1 0.59 7.3 0.12 95.56
124 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 95.52
125 INT23094 Positive_regulation of Positive_regulation of Ca2 29 0.49 6.8 9.35 95.52
126 INT272414 Positive_regulation of Positive_regulation of NARFL 9 0.37 12.88 0.84 95.40
127 INT32138 Positive_regulation of Neu2 3 0.02 0.86 0.33 95.36
128 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 95.28
129 INT22213 Localization of Gpt 52 0.78 34.05 12.94 95.28
130 INT24895 Positive_regulation of LYZ 25 0.70 17.92 2.64 95.16
131 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 95.00
132 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 94.96
133 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 94.96
134 INT9377 Positive_regulation of Positive_regulation of TRPV1 43 0.70 15.81 24.47 94.96
135 INT9378 Regulation of Positive_regulation of TRPV1 9 0.45 2.36 4.26 94.96
136 INT9376 Positive_regulation of Regulation of TRPV1 3 0.47 1.42 1.26 94.96
137 INT9382 Regulation of TRPV1 149 0.62 53.99 77.46 94.96
138 INT17561 Localization of Car2 303 0.79 60.95 44.52 94.88
139 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34 94.88
140 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65 94.66
141 INT265335 Negative_regulation of sb 2 0.00 0.57 0 94.64
142 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 94.64
143 INT35558 Binding of Sts 4 0.32 3.76 0.48 94.52
144 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 94.48
145 INT9385 Localization of LDHA 74 0.81 31.67 10.5 94.40
146 INT9380 Positive_regulation of Localization of LDHA 14 0.70 4.1 1.66 94.40
147 INT9379 Regulation of Localization of LDHA 4 0.27 0.96 0.06 94.40
148 INT10261 Negative_regulation of Pd 16 0.42 5.55 7.4 94.32
149 INT1127 Negative_regulation of IGHG3 32 0.28 21.1 7.37 94.28
150 INT70445 Binding of KRT1 10 0.35 5.38 0.47 94.24
151 INT232965 Binding of KRT10 3 0.19 1.66 0 94.24
152 INT15489 Negative_regulation of Gene_expression of SGCG 10 0.42 4.78 3.18 94.20
153 INT234930 Binding of Dsg3 25 0.48 20.73 0.44 94.16
154 INT234876 Negative_regulation of Dsg3 29 0.59 25.47 0.4 94.16
155 INT158563 Negative_regulation of Ctgf 6 0.56 4.31 1.12 94.16
156 INT188406 Binding of Fasl 19 0.44 24.67 3.17 94.16
157 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64 94.12
158 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4 94.08
159 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 94.08
160 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 94.00
161 INT231952 Positive_regulation of Myh1 14 0.62 0.82 0.27 93.92
162 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 93.80
163 INT9384 Positive_regulation of Positive_regulation of LDHA 3 0.50 5.5 0.52 93.76
164 INT44979 Positive_regulation of Pnp 11 0.59 5.61 2.41 93.76
165 INT92682 Positive_regulation of Gene_expression of Ctgf 17 0.69 12.16 4.51 93.72
166 INT148042 Binding of CMA1 2 0.47 1.43 0 93.72
167 INT284711 Localization of CMA1 3 0.78 2.1 0.82 93.72
168 INT255251 Negative_regulation of Smad2 12 0.32 5.69 1.44 93.68
169 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 93.64
170 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16 93.60
171 INT81578 Gene_expression of TRAP 25 0.72 9.75 2.82 93.60
172 INT237330 Transcription of PARPBP 3 0.22 1.78 3.48 93.36
173 INT137593 Regulation of Gene_expression of SLC6A4 7 0.60 2.59 5.23 93.36
174 INT313792 Regulation of Hspb2 1 0.08 1.47 0 93.36
175 INT235418 Gene_expression of cla 5 0.58 3.27 0.24 93.28
176 INT275143 Positive_regulation of Binding of HLA-E 1 0.16 0.32 0 93.04
177 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93 92.96
178 INT174986 Gene_expression of AIRN 20 0.57 6.13 0.64 92.96
179 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2 92.96
180 INT15543 Gene_expression of CASP8 32 0.75 25.6 2.61 92.96
181 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 92.80
182 INT4822 Localization of Ca2 417 0.80 99.57 96.45 92.68
183 INT180415 Regulation of Rhoa 7 0.53 3.92 0.22 92.64
184 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43 92.56
185 INT61649 Regulation of Negative_regulation of F13A1 1 0.00 0.67 0 92.56
186 INT178286 Positive_regulation of Hps1 9 0.61 3.86 0.5 92.48
187 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 92.48
188 INT282679 Localization of FECH 1 0.12 9.57 0.23 92.44
189 INT337910 Binding of Ctgf 1 0.22 3.04 0.15 92.40
190 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 92.40
191 INT159190 Gene_expression of KRT5 31 0.65 26.67 0.56 92.32
192 INT163232 Gene_expression of Invs 2 0.75 1.77 0.13 92.20
193 INT122901 Positive_regulation of Spp1 67 0.67 58.03 7.49 92.00
194 INT209355 Binding of SLC9A6 8 0.42 14.9 0.09 91.88
195 INT209417 Gene_expression of ERG 21 0.20 6.69 1.26 91.80
196 INT292050 Positive_regulation of Iba1 4 0.25 3.17 0.84 91.44
197 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 91.36
198 INT15089 Regulation of SLC6A4 48 0.62 17.87 25.6 91.36
199 INT1705 Gene_expression of pCA 126 0.65 88.65 34.81 91.28
200 INT234925 Positive_regulation of Phosphorylation of Hspb2 1 0.11 3.52 0.19 91.20
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