D:Bone Disease

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Disease Term
Synonyms Bone Diseases, Bone Disorder, Disease Bone, Disease Of Bone, Diseases Bone, Disorder Of Bone, Osteopathia, OSTEOPATHY
Documents 447
Hot Single Events 135
Hot Interactions 18

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Bone Disease. They are ordered first by their relevance to Bone Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT237669 Binding of PDB1 and SQSTM1 1 0.27 2.55 0 100.00
2 INT237670 SQSTM1 Regulation of PDB1 1 0.34 1.13 0.06 100.00
3 INT335743 Binding of PDB1 and Salpa1 1 0.01 1.66 0.09 100.00
4 INT335742 Binding of PDB1 and Dpyd 1 0.02 1.75 0.09 100.00
5 INT217486 Binding of PDB1 and Sqstm1 1 0.03 1.19 0.08 100.00
6 INT217487 Binding of PDB1 and Tnfrsf11a 1 0.03 0.76 0 100.00
7 INT188435 PDB1 Negative_regulation of Binding of SQSTM1 1 0.41 0.49 0 100.00
8 INT313308 Binding of SQSTM1 and KEAP1 1 0.46 1.16 0.1 96.88
9 INT188436 Negative_regulation of NUP62 Positive_regulation of TNFRSF11A 1 0.39 1.6 0 96.56
10 INT217474 Tnfrsf11a Regulation of Gene_expression of Tnfsf11 1 0.41 1.2 0.04 96.20
11 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 94.68
12 INT217473 Nup62 Regulation of Tnfrsf11a 1 0.38 0.66 0 94.24
13 INT313301 SQSTM1 Regulation of Protein_catabolism of KEAP1 1 0.43 0.58 0.1 93.72
14 INT217478 Binding of Tnfrsf11a and Traf6 1 0.39 1.22 0.17 91.68
15 INT217480 Tnfsf11 Negative_regulation of Tnfrsf11a 1 0.39 0.75 0 90.92
16 INT217477 Traf6 Positive_regulation of Binding of Nup62 1 0.32 0.47 0.09 90.64
17 INT217470 Traf6 Positive_regulation of Ngf 1 0.36 0.52 0.1 82.96
18 INT217476 Nup62 Positive_regulation of Ngf 1 0.37 0.52 0.1 82.96
19 INT215978 Binding of HPT and Pth 1 0.01 0.92 0 79.60
20 INT153740 TNFRSF11A Positive_regulation of Vcp 1 0.04 1.15 0.13 78.68
21 INT153739 TNFRSF11A Positive_regulation of Tnfrsf11b 1 0.05 1.14 0.13 78.68
22 INT153742 TNFRSF11A Positive_regulation of Tnfrsf11b 1 0.00 1.15 0.13 78.68
23 INT153738 TNFRSF11A Positive_regulation of SQSTM1 1 0.05 1.22 0.13 78.68
24 INT205989 Binding of SLC7A7 and PDAP1 1 0.02 1.77 0 75.56
25 INT270777 Binding of DMD and BPs 1 0.01 0.33 0.09 59.44
26 INT217467 Binding of Nup62 and Tnfrsf11a 1 0.31 0 0.05 35.72
27 INT217471 Binding of Nup62 and Traf6 1 0.26 0 0.05 35.48
28 INT217472 Binding of Nup62 and Mul1 1 0.12 0 0.05 31.72
29 INT217468 Positive_regulation of Binding of Nup62 and Mul1 1 0.16 0 0.05 31.72
30 INT313295 Binding of SQSTM1 and GABARAPL2 1 0.32 0.13 0 23.04
31 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3 5.00
32 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
33 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
34 INT209409 Binding of CALM1 and NHS 2 0.27 0.58 1.32 5.00
35 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18 5.00
36 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
37 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
38 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
39 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
40 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48 5.00
41 INT336021 EBM Regulation of Regulation of CALM1 1 0.18 0 0.32 5.00
42 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29 5.00
43 INT182634 Binding of CCR5 and MIP 2 0.39 1.29 0.2 5.00
44 INT206089 Negative_regulation of FOSB Negative_regulation of Gene_expression of PTGS2 1 0.00 0.97 0.19 5.00
45 INT206081 IL6ST Negative_regulation of IL6 1 0.11 0.81 0.17 5.00
46 INT206059 IL6 Positive_regulation of INS 1 0.02 1.16 0.16 5.00
47 INT206070 ANG Positive_regulation of Transcription of IL6 1 0.05 1.5 0.15 5.00
48 INT349222 CSF2 Positive_regulation of Gene_expression of SLC7A7 1 0.17 0.4 0.13 5.00
49 INT206065 EDN1 Positive_regulation of IL6 1 0.03 0.47 0.12 5.00
50 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1 5.00
51 INT206042 Negative_regulation of FDPS Negative_regulation of Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
52 INT206054 RAC1 Positive_regulation of STAT3 1 0.07 0.11 0.09 5.00
53 INT182644 Binding of CXCR4 and Cxcr4 1 0.10 0.66 0.09 5.00
54 INT206075 Negative_regulation of FDPS Negative_regulation of Binding of GGPS1 1 0.01 0 0.09 5.00
55 INT206078 Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
56 INT206072 ANG Positive_regulation of IL6 1 0.05 0.5 0.08 5.00
57 INT206080 ANG Regulation of Gene_expression of IL6 1 0.03 0.4 0.07 5.00
58 INT206063 ANG Positive_regulation of Gene_expression of KRT20 1 0.00 1.01 0.07 5.00
59 INT206087 RAC1 Positive_regulation of Gene_expression of STAT3 1 0.08 0.05 0.05 5.00
60 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04 5.00
61 INT206073 Negative_regulation of RAC1 Positive_regulation of IL6 1 0.14 0.06 0.04 5.00
62 INT206067 Gene_expression of RAC1 Positive_regulation of Positive_regulation of IL6 1 0.16 0.07 0.04 5.00
63 INT206068 RAC1 Positive_regulation of IL6 1 0.16 0.06 0.04 5.00
64 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04 5.00
65 INT349221 CSF2 Regulation of Gene_expression of SLC7A7 1 0.10 0.18 0.04 5.00
66 INT206071 IRF6 Positive_regulation of Positive_regulation of IL1B 1 0.00 0.58 0.03 5.00
67 INT264148 Binding of CLCN7 and Ostm1 1 0.17 0.72 0.03 5.00
68 INT206076 IL6 Positive_regulation of Positive_regulation of STAT3 1 0.19 0.3 0.03 5.00
69 INT206061 RAC1 Positive_regulation of Positive_regulation of STAT3 1 0.07 0.43 0.03 5.00
70 INT270775 PTH Regulation of DMD 1 0.09 0.64 0.03 5.00
71 INT270776 PTH Regulation of Negative_regulation of DMD 1 0.09 0.3 0.03 5.00
72 INT313305 SQSTM1 Regulation of NFE2L2 1 0.35 0.09 0 5.00
73 INT206085 FDPS Positive_regulation of AGFG1 1 0.00 0.4 0 5.00
74 INT335736 Binding of Map1lc3a and Map1lc3b 1 0.19 0.36 0 5.00
75 INT206058 EGFR Negative_regulation of Gene_expression of IL6 1 0.07 0.62 0 5.00
76 INT206079 ANG Regulation of KRT20 1 0.00 0.54 0 5.00
77 INT349219 PTPRC Positive_regulation of Gene_expression of SLC3A2 1 0.11 0.53 0 5.00
78 INT354566 F2 Positive_regulation of PRNP 1 0.00 0.05 0 5.00
79 INT313307 TERT Positive_regulation of NFE2L2 1 0.01 0 0 5.00
80 INT313293 Binding of KEAP1 and GOPC 1 0.04 0.24 0 5.00
81 INT206069 ANG Positive_regulation of Gene_expression of IL6 1 0.05 0.51 0 5.00
82 INT349220 Binding of CASP3 and CD8A 1 0.00 0.18 0 5.00
83 INT313298 Negative_regulation of SQSTM1 Positive_regulation of KEAP1 1 0.39 0.39 0 5.00
84 INT349225 TREM1 Positive_regulation of LAMB1 1 0.00 0 0 5.00
85 INT206088 IL6 Positive_regulation of JAK1 1 0.18 0.05 0 5.00
86 INT264143 TCIRG1 Regulation of BSND 1 0.02 0.74 0 5.00
87 INT270780 BPs Positive_regulation of DMD 1 0.02 0 0 5.00
88 INT313297 SQSTM1 Positive_regulation of Positive_regulation of NFE2L2 1 0.26 0 0 5.00
89 INT206178 Foxm1 Positive_regulation of Protein_catabolism of Olr1 1 0.00 0.47 0 5.00
90 INT313304 Binding of SQSTM1 and GOPC 1 0.04 0.24 0 5.00
91 INT206086 LDLR Positive_regulation of Localization of IL6 1 0.03 0.42 0 5.00
92 INT206060 FDPS Positive_regulation of AKT1 1 0.00 0.4 0 5.00
93 INT206055 F2 Positive_regulation of Gene_expression of IL6 1 0.01 1.24 0 5.00
94 INT206082 IL6 Positive_regulation of Gene_expression of CCL2 1 0.07 0.3 0 5.00
95 INT349224 Binding of CSF2 and SLC7A7 1 0.12 0.38 0 5.00
96 INT313299 Negative_regulation of Binding of NFE2L2 and KEAP1 1 0.24 0.14 0 5.00
97 INT264144 CLCN7 Regulation of ADO 1 0.04 0.71 0 5.00
98 INT206180 Foxm1 Positive_regulation of Transcription of Olr1 1 0.00 0.48 0 5.00
99 INT270778 Binding of TNFSF11 and CALCRL 1 0.00 0.44 0 5.00
100 INT206077 RAC1 Positive_regulation of Phosphorylation of STAT3 1 0.07 0.35 0 5.00
101 INT313296 Binding of KEAP1 and PGAM5 1 0.11 0.15 0 5.00
102 INT313290 Binding of NFE2L2 and Positive_regulation of Binding of NFE2L2 KEAP1 1 0.16 0.38 0 5.00
103 INT313303 Negative_regulation of SQSTM1 Positive_regulation of GOPC 1 0.05 0.39 0 5.00
104 INT313292 Positive_regulation of SQSTM1 Regulation of NFE2L2 1 0.26 0.09 0 5.00
105 INT197545 KEAP1 Regulation of NFE2L2 3 0.49 0.8 0 5.00
106 INT206181 FDPS Positive_regulation of ras 1 0.00 0.4 0 5.00
107 INT313310 KEAP1 Regulation of Gene_expression of SQSTM1 1 0.43 0.35 0 5.00
108 INT313302 Regulation of TERT Positive_regulation of SQSTM1 1 0.01 0 0 5.00
109 INT313311 SQSTM1 Positive_regulation of Positive_regulation of KEAP1 1 0.45 0 0 5.00
110 INT313291 TERT Positive_regulation of SQSTM1 1 0.02 0 0 5.00
111 INT313306 KEAP1 Positive_regulation of SPARC 1 0.02 0.37 0 5.00
112 INT349223 CSF2 Positive_regulation of SLC7A7 1 0.17 0.3 0 5.00
113 INT206084 EGF Negative_regulation of Gene_expression of IL6 1 0.05 0.61 0 5.00
114 INT313294 Negative_regulation of SQSTM1 Positive_regulation of Positive_regulation of KEAP1 1 0.39 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Bone Disease. They are ordered first by their pain relevance and then by number of times they were reported in Bone Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT155775 Gene_expression of PDB1 12 0.65 10.18 0.41 100.00
2 INT24459 Positive_regulation of PDB1 7 0.46 7 0.5 100.00
3 INT93017 Binding of PDB1 8 0.36 6.36 0.51 100.00
4 INT127432 Gene_expression of Nup62 20 0.71 11.01 0.71 100.00
5 INT24458 Negative_regulation of PDB1 8 0.41 4.5 1.5 100.00
6 INT188446 Gene_expression of SQSTM1 5 0.71 5.34 0.18 100.00
7 INT95670 Regulation of PDB1 4 0.60 5.59 0.55 100.00
8 INT34879 Localization of PDB1 5 0.59 2.38 0.54 100.00
9 INT38908 Phosphorylation of PDB1 2 0.46 1.56 0.23 100.00
10 INT188451 Localization of FSD1 1 0.02 1.21 0.14 100.00
11 INT155776 Positive_regulation of Gene_expression of PDB1 2 0.17 1.56 0.18 100.00
12 INT127433 Negative_regulation of Gene_expression of Nup62 2 0.53 2.36 0.08 100.00
13 INT217466 Negative_regulation of Gene_expression of PDB1 1 0.04 1.56 0 100.00
14 INT188452 Regulation of Gene_expression of PDB1 1 0.45 1.26 0 100.00
15 INT188447 Negative_regulation of Negative_regulation of PDB1 1 0.36 1.02 0.04 100.00
16 INT15390 Positive_regulation of Edn1 64 0.70 47.36 23.8 100.00
17 INT217465 Regulation of Positive_regulation of PDB1 1 0.04 0.69 0.05 100.00
18 INT188453 Localization of IGKV2D-18 1 0.01 0.6 0.07 100.00
19 INT188445 Localization of IGHVIII-67-3 1 0.08 0.6 0.07 100.00
20 INT166552 Negative_regulation of Binding of PDB1 1 0.09 0.44 0.07 100.00
21 INT93016 Binding of TNFRSF11A 29 0.47 19.67 4.17 99.96
22 INT45800 Phosphorylation of CALCA 2 0.67 0.64 0.18 99.96
23 INT217454 Positive_regulation of Gene_expression of Nup62 2 0.39 1.56 0.11 99.84
24 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 99.74
25 INT17803 Regulation of Edn1 14 0.54 4.75 4.71 99.74
26 INT335728 Positive_regulation of Dpyd 1 0.17 1.74 0.09 99.74
27 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 99.66
28 INT4342 Localization of ALPP 27 0.69 15.19 5.32 99.66
29 INT215976 Binding of HPT 1 0.20 0.95 0 99.60
30 INT37363 Localization of PTHLH 14 0.68 13.23 2.92 99.54
31 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.52
32 INT171962 Gene_expression of Tnfrsf11a 40 0.72 31.1 7.84 99.38
33 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26 99.30
34 INT188450 Negative_regulation of Gene_expression of ENPEP 1 0.06 0.91 0 99.28
35 INT217446 Negative_regulation of Binding of Nup62 1 0.33 1.54 0.25 99.26
36 INT217443 Regulation of Nup62 1 0.48 1.47 0.05 99.24
37 INT188444 Binding of SQSTM1 5 0.44 4.69 0.54 99.20
38 INT191765 Regulation of CALM1 15 0.52 9.52 8.56 99.16
39 INT4097 Localization of Pth 66 0.81 47.17 4.36 99.16
40 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 98.96
41 INT217452 Binding of Nup62 1 0.38 2.7 0.44 98.90
42 INT188449 Gene_expression of ENPEP 12 0.55 11.29 3.96 98.84
43 INT313329 Positive_regulation of Binding of KEAP1 1 0.46 0.44 0.11 98.84
44 INT313312 Positive_regulation of Binding of SQSTM1 1 0.46 0.44 0.11 98.84
45 INT44545 Gene_expression of Dclk2 5 0.65 0.77 1.41 98.84
46 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 98.84
47 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 98.76
48 INT10729 Positive_regulation of ENPEP 13 0.38 9.65 0.8 98.76
49 INT141896 Positive_regulation of SQSTM1 6 0.50 5.58 0.26 98.72
50 INT95668 Positive_regulation of Tnfrsf11a 12 0.47 10.14 1.34 98.60
51 INT45894 Negative_regulation of PTRH1 1 0.37 1.11 0.07 98.60
52 INT33568 Phosphorylation of CALM1 10 0.55 2.31 2.91 98.52
53 INT188454 Positive_regulation of NUP62 1 0.36 0.92 0 98.44
54 INT217445 Positive_regulation of Binding of Sqstm1 1 0.48 0.39 0 98.40
55 INT95667 Positive_regulation of Nfkb2 3 0.22 3.95 0.8 98.36
56 INT1636 Gene_expression of Sct 58 0.77 16.14 11.57 98.32
57 INT188456 Negative_regulation of Gene_expression of NUP62 1 0.33 0.99 0.05 97.54
58 INT175226 Gene_expression of NUP62 4 0.52 1.26 0.05 97.54
59 INT37350 Negative_regulation of ENPEP 7 0.42 1.15 1.7 97.44
60 INT217444 Binding of Sqstm1 1 0.46 0.38 0 97.02
61 INT217442 Regulation of Sqstm1 3 0.59 3.86 0.65 96.96
62 INT101815 Binding of KEAP1 6 0.44 5.29 0.39 96.88
63 INT217448 Regulation of Tnfrsf11a 1 0.42 2.31 0.14 96.76
64 INT117754 Gene_expression of NHS 34 0.57 9.27 3.28 96.76
65 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 96.64
66 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 96.64
67 INT16919 Gene_expression of IL36RN 48 0.48 32.78 13.83 96.64
68 INT36041 Negative_regulation of Gene_expression of IL36RN 11 0.11 9.47 4.46 96.64
69 INT188448 Negative_regulation of SQSTM1 4 0.53 3.75 0.55 96.56
70 INT188443 Negative_regulation of NUP62 1 0.33 1.53 0 96.56
71 INT144490 Regulation of Gene_expression of Tnfsf11 14 0.58 14.09 2.39 96.20
72 INT171959 Binding of Tnfrsf11a 15 0.34 11.03 3.02 96.12
73 INT56078 Negative_regulation of Protein_catabolism of NFKB1 7 0.42 4.44 1.83 96.08
74 INT56077 Protein_catabolism of NFKB1 16 0.98 8.03 3.94 96.08
75 INT6361 Localization of Edn1 30 0.81 19.09 9.7 96.08
76 INT6365 Localization of Edn1 56 0.81 18.84 13.83 96.08
77 INT124774 Binding of Vcp 4 0.44 3.4 0.52 95.92
78 INT119729 Binding of Tnfsf11 31 0.35 24.02 7.45 95.92
79 INT217438 Binding of Chuk 24 0.25 7.29 1.29 95.92
80 INT118264 Binding of Hmbs 6 0.37 4.87 0.33 95.92
81 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79 95.84
82 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66 95.68
83 INT215975 Regulation of HPT 3 0.26 2.75 0.66 95.56
84 INT743 Negative_regulation of Salpa1 16 0.57 8.75 3.1 95.36
85 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43 95.24
86 INT61466 Positive_regulation of Acp5 15 0.66 10.17 1.16 95.08
87 INT56072 Negative_regulation of NFKB1 94 0.59 53.16 28.19 94.80
88 INT34723 Regulation of Mbl1 2 0.41 2.26 0.63 94.52
89 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 94.32
90 INT217447 Positive_regulation of Positive_regulation of Nfatc1 4 0.46 3.34 2.2 94.12
91 INT6661 Positive_regulation of Positive_regulation of Jun 31 0.50 7.12 3.89 94.12
92 INT99088 Gene_expression of HPT 5 0.59 9.1 6.72 94.12
93 INT215974 Positive_regulation of HPT 1 0.21 1.55 0 94.12
94 INT175894 Regulation of IGHVIII-67-3 2 0.05 1.05 0.15 93.68
95 INT194748 Positive_regulation of Nfatc1 16 0.64 5.07 2.44 93.64
96 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73 93.64
97 INT29555 Positive_regulation of CALM1 58 0.69 14.09 17.37 93.48
98 INT157302 Positive_regulation of Map1lc3a 27 0.66 11.31 0.79 93.20
99 INT175219 Binding of NUP62 31 0.27 4.51 0.53 93.12
100 INT197575 Protein_catabolism of KEAP1 4 0.91 3.44 0.23 92.88
101 INT217464 Binding of Traf6 5 0.29 1.28 0.35 92.72
102 INT273531 Gene_expression of BRON-J 1 0.31 5.53 0.75 92.12
103 INT153769 Negative_regulation of Tnfrsf11a 4 0.39 2.13 1.05 91.76
104 INT217461 Negative_regulation of Positive_regulation of Nup62 1 0.33 0.41 0.07 91.76
105 INT33567 Gene_expression of CALM1 139 0.67 48.85 56.14 90.88
106 INT217463 Positive_regulation of Nup62 5 0.39 1.79 0.17 90.88
107 INT4819 Gene_expression of ACTG1 2 0.30 0.22 0.67 90.88
108 INT313318 Negative_regulation of Localization of SQSTM1 1 0.39 0.59 0.14 90.76
109 INT313320 Localization of SQSTM1 1 0.68 0.59 0.14 90.40
110 INT273529 Phosphorylation of BRON-J 1 0.38 1.09 0.03 89.88
111 INT136555 Negative_regulation of Tnfsf11 31 0.55 22.23 6.23 89.00
112 INT194031 Regulation of SQSTM1 2 0.41 2.07 0.27 88.72
113 INT4304 Localization of Salpa1 2 0.73 1.06 0.56 88.40
114 INT9499 Negative_regulation of Localization of Salpa1 1 0.42 0.55 0.21 88.40
115 INT197563 Regulation of KEAP1 10 0.56 3.18 0.11 87.20
116 INT45555 Negative_regulation of HOPX 1 0.02 0.32 0.08 86.56
117 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 85.92
118 INT335733 Positive_regulation of Tardbp 8 0.69 28.41 0.41 85.72
119 INT61264 Regulation of Jun 36 0.61 18.42 8.71 85.40
120 INT111534 Regulation of Nfatc1 11 0.29 2.11 1.77 85.40
121 INT182621 Localization of MLH1 9 0.64 9.31 0.12 85.40
122 INT273530 Negative_regulation of Localization of BRON-J 1 0.20 1.06 0.03 84.76
123 INT4238 Negative_regulation of ALPI 7 0.58 3.31 0.62 84.52
124 INT273528 Localization of BRON-J 1 0.35 1.06 0.03 84.24
125 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 83.92
126 INT217723 Regulation of IDS 15 0.25 2.12 0.49 83.76
127 INT148562 Positive_regulation of GNAS 13 0.16 5.31 1.32 82.36
128 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 82.16
129 INT93908 Negative_regulation of Dpyd 9 0.45 3.19 0.78 82.16
130 INT32165 Binding of CALM1 92 0.48 24.19 29.57 81.48
131 INT217453 Regulation of Positive_regulation of Tnfrsf11a 1 0.42 0.38 0.05 81.04
132 INT205995 Gene_expression of SLC7A7 11 0.75 10.61 1.21 80.52
133 INT164189 Gene_expression of TREM1 82 0.62 60.77 5.85 80.52
134 INT313313 Positive_regulation of Gene_expression of SQSTM1 1 0.63 1.25 0.23 80.32
135 INT217459 Regulation of Gene_expression of Nup62 1 0.35 0.35 0 80.28
136 INT95669 Regulation of TNFRSF11A 7 0.56 10.01 0.94 79.80
137 INT215977 Localization of HPT 2 0.36 3.43 2.19 79.76
138 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 79.60
139 INT101302 Positive_regulation of Gene_expression of Aif1 5 0.37 3.56 1.23 79.52
140 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 79.40
141 INT101301 Gene_expression of Aif1 17 0.42 16.43 4.06 79.12
142 INT173576 Negative_regulation of FDPS 25 0.57 8.42 1.91 78.96
143 INT846 Positive_regulation of B2M 42 0.70 29.78 8.06 78.56
144 INT217457 Negative_regulation of Nup62 2 0.33 0.94 0 78.04
145 INT303287 Gene_expression of Tardbp 4 0.77 44.78 1.09 77.36
146 INT194030 Regulation of UBAP1 1 0.03 1.34 0.13 77.00
147 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 76.84
148 INT93948 Negative_regulation of Gene_expression of Il12a 48 0.55 27.77 16.87 76.80
149 INT150384 Binding of RCT 10 0.25 3.1 2.05 76.48
150 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2 76.40
151 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 76.16
152 INT175482 Positive_regulation of Gene_expression of CALM1 12 0.44 3.47 6.54 75.84
153 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 75.24
154 INT37530 Regulation of Salpa1 8 0.59 4.79 1.19 75.00
155 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15 75.00
156 INT10094 Negative_regulation of ALPP 36 0.37 20.45 6.45 75.00
157 INT139291 Positive_regulation of COL4A6 1 0.50 0.77 0.09 75.00
158 INT4241 Regulation of CALCA 87 0.62 28.19 55.29 75.00
159 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34 75.00
160 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 75.00
161 INT11562 Regulation of KIAA0101 2 0.26 1.57 0.85 75.00
162 INT40583 Regulation of ALPI 4 0.45 1.87 0.48 75.00
163 INT118054 Regulation of ARMC9 23 0.34 11.32 1.06 74.80
164 INT288 Positive_regulation of Sct 88 0.70 32.83 24.5 74.52
165 INT172479 Positive_regulation of NFE2L2 74 0.70 35.22 0.79 73.84
166 INT177875 Positive_regulation of Positive_regulation of NFE2L2 18 0.66 9.4 0.4 73.84
167 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 73.80
168 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 73.12
169 INT425 Localization of PRL 455 0.81 189.64 144.8 71.60
170 INT2649 Regulation of Calca 433 0.62 146.05 330.95 71.04
171 INT213750 Positive_regulation of NHS 14 0.59 2.17 1.43 70.80
172 INT237045 Positive_regulation of Vcp 7 0.62 6.96 0.12 67.48
173 INT335738 Positive_regulation of VCP 1 0.06 1.88 0.06 66.80
174 INT7337 Regulation of Localization of CALM1 4 0.39 1.1 1.15 66.12
175 INT197562 Positive_regulation of KEAP1 16 0.63 6.78 0.08 66.00
176 INT7339 Localization of CALM1 46 0.75 16.15 16.47 65.52
177 INT217458 Protein_catabolism of Ubc 1 0.10 0.19 0.03 65.20
178 INT15746 Negative_regulation of PDAP1 13 0.52 6.45 1.12 63.64
179 INT205991 Negative_regulation of SLC7A7 9 0.41 1.81 0.12 63.64
180 INT349239 Gene_expression of CAA 1 0.75 1.53 0 62.68
181 INT60423 Positive_regulation of TPSG1 11 0.57 11.02 2.55 62.44
182 INT202166 Positive_regulation of Clec2g 1 0.38 0.68 0 61.44
183 INT335735 Binding of Atp13a3 2 0.03 1.17 0.24 59.12
184 INT38673 Negative_regulation of KRT20 38 0.42 22.49 2.77 56.96
185 INT77925 Negative_regulation of TEP1 21 0.53 15.23 2.62 55.60
186 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 55.56
187 INT15686 Regulation of PDAP1 6 0.45 2 0.78 55.20
188 INT35132 Gene_expression of PDAP1 18 0.52 9.05 1.5 53.36
189 INT171998 Binding of DMD 58 0.47 38.13 3.35 53.04
190 INT173808 Positive_regulation of CYP27A1 35 0.68 23.7 7.87 51.56
191 INT173809 Positive_regulation of TRMT2A 4 0.01 2.21 0.18 51.40
192 INT292763 Localization of Tardbp 6 0.80 12.51 0.91 51.20
193 INT273526 Positive_regulation of BRON-J 1 0.23 1.2 0.1 51.04
194 INT273527 Positive_regulation of Gene_expression of BRON-J 1 0.23 0.62 0.04 51.04
195 INT160283 Localization of NHS 7 0.65 2.48 1.52 50.72
196 INT43900 Gene_expression of RASA1 13 0.58 12 2.03 50.00
197 INT170813 Gene_expression of Prdm6 11 0.65 4.35 0.88 50.00
198 INT175365 Localization of Prdm6 2 0.54 0.1 0.05 50.00
199 INT237668 Regulation of Prdm6 3 0.20 1.49 0.03 50.00
200 INT300718 Negative_regulation of Ptrf 1 0.34 4.1 0.18 49.36
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