D:Bone Fracture

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Disease Term
Synonyms BONE BROKEN, Bone Fractures, Bone Injury, Bones Broken, Broken Bone, BROKEN BONES, Broken Hip, FIBIA FRACTURE, FRACTURE BONE, Fracture Of Fibia, Fracture Of Hip
Documents 646
Hot Single Events 105
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Bone Fracture. They are ordered first by their relevance to Bone Fracture and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT274531 Il6 Regulation of Localization of Lpl 1 0.04 1.49 0.33 94.04
2 INT274530 Il6 Regulation of Lpl 1 0.07 1.48 0.32 94.04
3 INT249968 Cxcr4 Positive_regulation of Cxcl12 1 0.17 0.55 0.08 86.08
4 INT144500 CCL3 Positive_regulation of Gene_expression of Tnfsf11 1 0.77 1.62 0.31 80.52
5 INT147278 Negative_regulation of Calca Positive_regulation of Th 1 0.41 0.76 0.74 75.00
6 INT147277 Calca Positive_regulation of Th 1 0.48 0.76 0.74 75.00
7 INT147280 Binding of Pecam1 and Th 1 0.29 0.41 0.41 75.00
8 INT147279 Binding of Calca and Pecam1 1 0.33 0.4 0.47 75.00
9 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18 69.84
10 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18 69.84
11 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23 68.24
12 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18 68.24
13 INT310612 OTOR Positive_regulation of F13A1 1 0.05 0.36 0.06 30.08
14 INT339287 Binding of Cxcr2 and Cxcl1 1 0.29 0.48 0.24 25.60
15 INT249962 Binding of KIT and KITLG 6 0.19 3.69 0.17 25.60
16 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 22.56
17 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 21.08
18 INT351379 Ngf Positive_regulation of Binding of Ngf and Ntrk1 1 0.38 0.63 1.21 16.08
19 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91 11.92
20 INT332639 Glp1r Negative_regulation of Localization of Gcg 1 0.03 0.87 0.07 11.92
21 INT342288 Binding of CD4 and HFE 1 0.01 1.26 0.08 7.96
22 INT351380 Ngf Regulation of TPM1 1 0.44 2.17 2.11 5.00
23 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3 5.00
24 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 5.00
25 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 5.00
26 INT341479 Binding of SCN2A and SCN4A 1 0.37 1.29 0.98 5.00
27 INT341480 Binding of SCN1A and SCN4A 1 0.36 1.29 0.98 5.00
28 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
29 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
30 INT339293 Casp1 Regulation of Localization of Il1 1 0.07 1.87 0.83 5.00
31 INT339291 Casp1 Positive_regulation of Il1 2 0.12 1.63 0.8 5.00
32 INT351374 Mir470 Negative_regulation of Ntrk3 1 0.00 1.55 0.7 5.00
33 INT351375 Mir470 Negative_regulation of Ntrk2 1 0.01 1.54 0.7 5.00
34 INT351376 Mir470 Negative_regulation of Ntrk1 1 0.01 1.54 0.7 5.00
35 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 5.00
36 INT339290 Casp1 Regulation of Gene_expression of Il1 1 0.11 1.38 0.55 5.00
37 INT339275 Il6 Regulation of KRT20 1 0.00 3.11 0.49 5.00
38 INT224423 Binding of TNFRSF11B and TNFRSF11A 3 0.19 2.36 0.37 5.00
39 INT278389 Binding of Casp1 and Il1 2 0.09 0.82 0.36 5.00
40 INT239398 Atp7b Regulation of OAP 1 0.03 1.1 0.35 5.00
41 INT254344 Binding of Col2a1 and Ncoa5 1 0.00 0.98 0.35 5.00
42 INT210597 Negative_regulation of Binding of TNFSF11 and TNFRSF11A 3 0.26 5.66 0.33 5.00
43 INT330620 S100a8 Positive_regulation of Positive_regulation of TNF 1 0.03 1.92 0.32 5.00
44 INT222299 Binding of CYP19A1 and AIS 2 0.25 1.65 0.31 5.00
45 INT323855 IL6 Positive_regulation of Positive_regulation of TNF 1 0.04 1.03 0.31 5.00
46 INT339294 Il1 Positive_regulation of Gene_expression of Cxcl1 1 0.06 0.53 0.3 5.00
47 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29 5.00
48 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27 5.00
49 INT239396 Atp7b Negative_regulation of Gene_expression of Icam1 1 0.07 1.69 0.26 5.00
50 INT339903 Binding of SCN5A and ZGLP1 1 0.01 0.18 0.22 5.00
51 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21 5.00
52 INT339292 Il1 Positive_regulation of Gene_expression of Ptger2 1 0.02 0.4 0.2 5.00
53 INT339901 Binding of INS and SCN5A 1 0.01 0.18 0.2 5.00
54 INT244299 FFAR1 Positive_regulation of PTH1R 1 0.00 0.4 0.2 5.00
55 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
56 INT222300 Binding of ERBB2 and PGR 2 0.34 1.89 0.17 5.00
57 INT298641 PPARA Regulation of STAT3 1 0.23 0.98 0.16 5.00
58 INT239393 Atp7b Positive_regulation of Gene_expression of Amigo2 1 0.03 1.37 0.16 5.00
59 INT239395 Atp7b Positive_regulation of Amigo2 1 0.03 1.36 0.16 5.00
60 INT239394 Atp7b Positive_regulation of Positive_regulation of Amigo2 1 0.03 1.36 0.16 5.00
61 INT310626 Ambp Regulation of OTOR 1 0.15 1.04 0.14 5.00
62 INT298639 GDE1 Negative_regulation of AKT1 1 0.00 1.14 0.14 5.00
63 INT334541 Binding of HIVEP1 and TNF 1 0.01 1.32 0.13 5.00
64 INT239397 OAP Positive_regulation of Amigo2 1 0.00 0.56 0.1 5.00
65 INT332637 Negative_regulation of Dpp4 Negative_regulation of Localization of Ins1 1 0.06 1.66 0.1 5.00
66 INT246478 Binding of SERPINE1 and ANGPTL5 1 0.01 1.32 0.1 5.00
67 INT199436 Binding of Capns1 and Cysltr1 1 0.00 0.79 0.1 5.00
68 INT308225 Alb Positive_regulation of Binding of EIF4G2 1 0.02 0.33 0.09 5.00
69 INT298634 Binding of IL6 and STAT3 1 0.04 1.41 0.08 5.00
70 INT211960 Wnt5a Positive_regulation of Car2 1 0.13 0.38 0.08 5.00
71 INT346695 Negative_regulation of SOD1 Positive_regulation of Negative_regulation of Hist3h2a 1 0.00 0.41 0.08 5.00
72 INT213933 AR Negative_regulation of Cyp19a1 1 0.07 0.79 0.07 5.00
73 INT227418 Binding of DLAT and Pdc 1 0.05 1.01 0.07 5.00
74 INT332641 Binding of PPARG and Ins1 1 0.12 1.05 0.05 5.00
75 INT298638 IL6 Positive_regulation of IL6R 1 0.00 0.9 0.05 5.00
76 INT332631 Negative_regulation of Dpp4 Negative_regulation of Gcg 1 0.05 1 0.05 5.00
77 INT339272 VDR Positive_regulation of Gene_expression of KRT20 1 0.00 0.07 0.05 5.00
78 INT308291 LY6E Regulation of EPC1 1 0.00 0 0.05 5.00
79 INT332628 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Gcg 1 0.05 1 0.05 5.00
80 INT308292 CSF2 Positive_regulation of EPC1 1 0.10 0 0.05 5.00
81 INT332638 Gip Regulation of Glp1r 1 0.02 0.47 0.05 5.00
82 INT298635 PPARA Negative_regulation of Localization of ZDHHC2 1 0.01 0.21 0.05 5.00
83 INT332633 Glp1r Negative_regulation of Gcg 1 0.04 1.13 0.05 5.00
84 INT332632 Gip Negative_regulation of Localization of Gcg 1 0.05 0.47 0.04 5.00
85 INT210596 TNFRSF11B Negative_regulation of Binding of TNFSF11 2 0.11 1.62 0.04 5.00
86 INT298683 ecs Positive_regulation of Gene_expression of VEGFA 1 0.02 1.41 0.04 5.00
87 INT210593 TNFRSF11B Negative_regulation of Binding of TNFSF11 and TNFRSF11A 2 0.10 1.62 0.04 5.00
88 INT332635 Glp1r Regulation of Localization of Gcg 1 0.03 0.94 0.04 5.00
89 INT308290 LY6E Positive_regulation of EPC1 1 0.00 0 0.04 5.00
90 INT298637 ZDHHC2 Negative_regulation of Gene_expression of VEGFA 1 0.01 0.27 0.04 5.00
91 INT332640 Glp1r Regulation of Localization of Ins1 1 0.04 0.52 0.04 5.00
92 INT298633 STAT3 Regulation of MCL1 1 0.04 0.85 0.03 5.00
93 INT246480 Binding of ALB and SHBG 2 0.14 1.45 0.03 5.00
94 INT298640 IL6R Positive_regulation of STAT3 1 0.01 0.73 0.03 5.00
95 INT314771 Glp1r Positive_regulation of Gene_expression of Ins1 2 0.04 1.23 0.03 5.00
96 INT174532 PTH Positive_regulation of Transcription of IGF1 1 0.06 0.51 0 5.00
97 INT298684 ecs Positive_regulation of Gene_expression of KDR 1 0.01 1.2 0 5.00
98 INT353551 Pck1 Regulation of SLC17A5 1 0.00 0 0 5.00
99 INT353549 Pck1 Regulation of Gene_expression of Gpt 1 0.00 0 0 5.00
100 INT332629 Binding of Glp1r and Positive_regulation of Localization of Gcg 1 0.03 0.47 0 5.00
101 INT316101 Binding of HIST1H4PS1 and ANGPTL5 1 0.01 0.28 0 5.00
102 INT329479 Binding of TNFRSF11B and TNF 1 0.04 0.71 0 5.00
103 INT256825 Binding of Atp2b4 and Chordc1 1 0.02 0.27 0 5.00
104 INT278021 BMP2 Positive_regulation of Gene_expression of RUNX1T1 1 0.02 0.5 0 5.00
105 INT332636 Binding of Glp1r and Positive_regulation of Localization of Ins1 1 0.03 0.47 0 5.00
106 INT332634 Dpp4 Positive_regulation of Localization of Ins1 1 0.06 0.76 0 5.00
107 INT316414 Binding of LDLR and T2dm2 1 0.00 1.54 0 5.00
108 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0 5.00
109 INT353550 Pck1 Regulation of Gpt 1 0.00 0 0 5.00
110 INT255385 Binding of COL1A2 and DSPP 1 0.40 0.12 0 5.00
111 INT339288 Binding of Hprt1 and Il1 1 0.09 0.05 0 5.00
112 INT255384 Binding of AKR1C2 and DSG1 1 0.01 1.54 0 5.00
113 INT332627 Positive_regulation of Ins1 Positive_regulation of Phosphorylation of Hk2 1 0.01 0.83 0 5.00
114 INT298632 STAT3 Positive_regulation of MIR21 1 0.03 0.84 0 5.00
115 INT332159 Gh Positive_regulation of Gene_expression of Igfbp3 1 0.07 1.11 0 5.00
116 INT256882 Binding of Atp2b4 and Chordc1 Regulation of Nod1 1 0.01 0.27 0 5.00
117 INT321594 Bmp2 Regulation of Gene_expression of Lxn 1 0.42 1.71 0 5.00
118 INT339217 MMP9 Negative_regulation of VEGFA 1 0.05 0.38 0 5.00
119 INT329480 Binding of TNFRSF11B and TNFSF10 1 0.03 0.71 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Bone Fracture. They are ordered first by their pain relevance and then by number of times they were reported in Bone Fracture. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT123701 Negative_regulation of VDR 61 0.59 48.94 9.67 99.96
2 INT227759 Gene_expression of Best1 26 0.42 20.36 1.73 99.92
3 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29 99.76
4 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49 99.74
5 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 99.56
6 INT147582 Negative_regulation of AIS 13 0.37 13.26 2.46 98.84
7 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 98.80
8 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 98.72
9 INT211969 Positive_regulation of Best1 34 0.11 14.92 1.44 98.60
10 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15 97.88
11 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 97.68
12 INT81229 Binding of COL1A1 24 0.35 12.07 3.3 97.52
13 INT173159 Localization of PPARA 96 0.74 64.55 10.26 97.48
14 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 97.40
15 INT228167 Negative_regulation of Peg10 18 0.02 7.64 0.54 97.24
16 INT69035 Positive_regulation of Casp1 43 0.69 25.18 10.67 97.20
17 INT205692 Positive_regulation of Positive_regulation of Casp1 5 0.46 3 2.44 97.20
18 INT196995 Gene_expression of TMEM200A 22 0.45 4.02 0.53 97.04
19 INT196991 Negative_regulation of TMEM200A 7 0.28 1.31 0 97.04
20 INT281995 Positive_regulation of Gene_expression of TMEM200A 2 0.22 0.47 0 97.04
21 INT77314 Gene_expression of Lxn 3 0.76 5.67 1.55 96.92
22 INT91704 Positive_regulation of Alpl 3 0.66 2.92 0.82 96.52
23 INT129832 Positive_regulation of Positive_regulation of PTH 5 0.50 3.4 0.14 96.52
24 INT129831 Positive_regulation of Positive_regulation of Alpl 1 0.42 0.97 0.1 96.52
25 INT9951 Gene_expression of ANGPTL5 45 0.53 37.2 6.44 96.24
26 INT114395 Positive_regulation of Nlrp1a 15 0.45 4.61 15.37 96.20
27 INT114664 Binding of BMP2 12 0.37 6.54 0.91 96.16
28 INT114663 Regulation of Binding of BMP2 1 0.38 0.19 0.09 96.16
29 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 95.90
30 INT119700 Gene_expression of VDR 88 0.75 65.33 11.5 95.84
31 INT545 Binding of GC 15 0.45 10.74 3.47 95.80
32 INT16165 Regulation of DMD 114 0.60 35.13 3.64 95.72
33 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 95.56
34 INT13416 Positive_regulation of Pthlh 19 0.60 14.78 3.74 95.40
35 INT227758 Positive_regulation of Localization of Best1 3 0.07 1.95 0 95.00
36 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37 94.92
37 INT211968 Localization of Best1 11 0.40 9.33 0.38 94.80
38 INT37590 Regulation of COL7A1 15 0.54 9.4 3.12 94.76
39 INT12598 Binding of DBP 20 0.48 13.11 3.62 94.72
40 INT743 Negative_regulation of Salpa1 16 0.57 8.75 3.1 94.64
41 INT241549 Negative_regulation of Gene_expression of AIS 5 0.37 3.72 0.48 94.28
42 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 94.24
43 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 94.08
44 INT19511 Localization of Il6 212 0.81 118.17 67.67 94.04
45 INT219928 Negative_regulation of Prtg 1 0.19 0.6 0.13 93.84
46 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 93.76
47 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 93.76
48 INT211971 Binding of Best1 16 0.22 7.73 0.33 93.60
49 INT22499 Regulation of Calca 42 0.62 17.32 28.02 93.52
50 INT143666 Positive_regulation of ST2 15 0.69 11.76 0.85 93.28
51 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 92.98
52 INT65208 Positive_regulation of Positive_regulation of COL1A2 3 0.14 2.63 0.32 92.88
53 INT62669 Positive_regulation of COL1A2 13 0.49 6.89 1.4 92.88
54 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01 92.80
55 INT131783 Localization of Nociq1 2 0.60 1.46 1.08 92.68
56 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66 92.36
57 INT159643 Regulation of Gan 3 0.25 3.02 1.2 92.16
58 INT191774 Gene_expression of Amigo2 2 0.05 6.81 1.03 91.92
59 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28 91.88
60 INT116738 Positive_regulation of Gene_expression of Mif 14 0.68 10.99 3.8 91.88
61 INT219927 Regulation of Prtg 1 0.13 0.65 0.13 91.84
62 INT274529 Localization of Lpl 2 0.46 2.31 0.32 91.80
63 INT49437 Gene_expression of OAP 25 0.54 20.12 7.34 91.76
64 INT65207 Positive_regulation of Positive_regulation of Fgf2 10 0.70 3.5 2.08 91.52
65 INT85808 Localization of BMP2 7 0.77 1.94 0.51 91.52
66 INT69034 Regulation of Casp1 3 0.27 3.56 1.36 90.16
67 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83 89.64
68 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27 89.64
69 INT267750 Binding of Casp1 4 0.35 1.53 1.02 89.48
70 INT49238 Protein_catabolism of COL1A2 30 0.97 15.64 3.45 89.12
71 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 89.04
72 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 89.00
73 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 89.00
74 INT131848 Positive_regulation of Gene_expression of RHOC 9 0.64 15.43 1.36 88.96
75 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 88.64
76 INT10706 Regulation of Il6 150 0.62 93.23 62.34 88.60
77 INT131850 Gene_expression of RHOC 17 0.72 29.06 2.28 88.56
78 INT68744 Localization of Cxcl1 18 0.80 8.65 8.6 88.56
79 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 88.20
80 INT2072 Localization of AMBP 33 0.65 37.58 4.84 87.28
81 INT171998 Binding of DMD 58 0.47 38.13 3.35 87.24
82 INT94947 Positive_regulation of Transcription of Il6 9 0.67 6.91 3.04 87.00
83 INT16622 Positive_regulation of PLXNA3 6 0.67 5.2 1.69 86.88
84 INT252968 Positive_regulation of TAF9 11 0.45 5.28 3.68 86.64
85 INT190075 Regulation of Transcription of Il6 2 0.45 2.17 1.18 86.60
86 INT136309 Positive_regulation of Cxcl12 24 0.62 12.45 5.58 86.08
87 INT50933 Transcription of Il6 38 0.72 24.31 11.58 85.92
88 INT274377 Localization of TERT 3 0.70 0.78 0 85.92
89 INT70848 Gene_expression of Casp1 24 0.77 10.97 8.52 85.84
90 INT163787 Gene_expression of Nlrp1a 1 0.77 4 3.24 85.84
91 INT149069 Positive_regulation of Cxcr4 24 0.68 12.21 9.54 85.16
92 INT103094 Binding of PPARA 308 0.47 177.26 34.75 84.92
93 INT37758 Gene_expression of GC 10 0.75 7.09 1.75 84.76
94 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24 84.36
95 INT213739 Gene_expression of Expi 7 0.47 1.05 0.63 84.12
96 INT321589 Negative_regulation of Lxn 1 0.37 0.32 0 83.76
97 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 83.44
98 INT160673 Gene_expression of Ambp 16 0.49 19.49 2.3 83.32
99 INT2649 Regulation of Calca 433 0.62 146.05 330.95 82.64
100 INT131851 Positive_regulation of RHOC 3 0.57 9.44 0.41 82.20
101 INT69033 Negative_regulation of Casp1 21 0.58 13.15 7.52 81.52
102 INT180734 Gene_expression of Emid1 3 0.65 6.83 0.21 81.20
103 INT178818 Regulation of Gene_expression of Il18 3 0.40 2.98 0.68 81.04
104 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95 81.04
105 INT189130 Regulation of AIS 11 0.39 7.64 0.99 80.40
106 INT222233 Gene_expression of Cxcl12 42 0.69 32.64 10.13 79.28
107 INT222230 Positive_regulation of Gene_expression of Cxcl12 11 0.59 5.26 2.13 79.28
108 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95 78.40
109 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43 78.20
110 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 78.16
111 INT131849 Negative_regulation of RHOC 4 0.54 6.46 0.34 78.08
112 INT131852 Positive_regulation of Negative_regulation of RHOC 1 0.46 1.12 0.12 78.08
113 INT131847 Negative_regulation of Gene_expression of RHOC 2 0.39 1.38 0.12 77.88
114 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48 77.84
115 INT107407 Regulation of KCNE1 3 0.39 2.18 0.88 77.76
116 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 77.64
117 INT211970 Negative_regulation of Best1 49 0.14 37.33 2.32 76.96
118 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56 76.80
119 INT104207 Positive_regulation of Gene_expression of Tnfsf11 43 0.69 25.8 7.35 76.28
120 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53 76.28
121 INT51150 Positive_regulation of HTC2 10 0.67 6.8 2.95 76.08
122 INT319129 Regulation of Regulation of Fgfr1op 1 0.14 0.97 0.13 75.52
123 INT64171 Regulation of CPOX 109 0.36 55.36 32.96 75.40
124 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82 75.16
125 INT152906 Regulation of Gene_expression of Cxcl1 10 0.44 5.83 2.69 75.16
126 INT102638 Regulation of VDR 21 0.44 9.92 2.54 75.12
127 INT219 Negative_regulation of Th 55 0.59 20.88 17.09 75.00
128 INT319130 Regulation of Fgfr1op 1 0.14 0.96 0.13 74.64
129 INT79234 Positive_regulation of CCL3 15 0.67 11.43 4.15 74.64
130 INT18925 Gene_expression of Paics 3 0.52 1.25 0.93 74.64
131 INT256411 Phosphorylation of AMBP 1 0.08 10.3 0.73 74.00
132 INT249732 Gene_expression of Itgb6 1 0.03 10.37 2.63 73.48
133 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26 73.40
134 INT172592 Positive_regulation of PTH1R 9 0.28 6.25 2.5 73.32
135 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42 73.08
136 INT157570 Negative_regulation of Zfp469 1 0.04 1.01 1.07 72.96
137 INT116737 Localization of Mif 63 0.81 52.97 28.11 72.72
138 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 72.12
139 INT191221 Positive_regulation of Amigo2 20 0.12 24.24 2.31 72.00
140 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 71.72
141 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 71.72
142 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 71.00
143 INT25608 Regulation of Gene_expression of Il1 37 0.44 27.76 10.1 71.00
144 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57 70.96
145 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 70.96
146 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99 70.96
147 INT111594 Positive_regulation of Gene_expression of NOSTRIN 20 0.32 8.69 5 70.96
148 INT37296 Binding of Esr1 117 0.43 62.51 27.33 70.92
149 INT9098 Positive_regulation of DBP 30 0.69 15.77 4.26 70.72
150 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 70.44
151 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 70.36
152 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 70.32
153 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 70.12
154 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57 70.12
155 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 70.12
156 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 70.08
157 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28 69.84
158 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 68.88
159 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 68.64
160 INT110767 Localization of Mcpt1 43 0.68 24.3 16.74 68.56
161 INT96073 Localization of Casp1 11 0.78 4.91 1.29 67.84
162 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 67.76
163 INT8101 Binding of INCENP 42 0.31 16.2 6.68 67.04
164 INT311041 Negative_regulation of Acp5 1 0.09 1.79 0 66.96
165 INT311037 Negative_regulation of Negative_regulation of Acp5 1 0.09 0.9 0 66.96
166 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 66.76
167 INT53949 Positive_regulation of Gene_expression of Cpox 82 0.65 38.12 25.93 66.76
168 INT76924 Positive_regulation of Slc17a5 71 0.70 41.21 19.31 66.24
169 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03 66.08
170 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94 65.76
171 INT130866 Positive_regulation of Gene_expression of TNFSF11 25 0.69 7.11 1.82 65.40
172 INT130867 Gene_expression of TNFSF11 106 0.77 45.15 10.34 65.00
173 INT108913 Positive_regulation of HAL 10 0.28 5.71 1.59 64.88
174 INT66191 Gene_expression of DBP 42 0.66 22.25 3.18 64.84
175 INT16609 Localization of FFAR1 8 0.40 2.65 0.81 64.48
176 INT66026 Gene_expression of Cxcl1 74 0.78 31.87 23.37 64.44
177 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 64.40
178 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 64.16
179 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 63.84
180 INT6906 Negative_regulation of SCN5A 64 0.43 20.64 7.3 63.84
181 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 63.44
182 INT5096 Positive_regulation of Gtf3a 79 0.60 42.26 20.62 63.44
183 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 63.04
184 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21 63.04
185 INT163783 Transcription of Casp1 1 0.58 0.88 0.73 63.00
186 INT163784 Transcription of Nlrp1a 1 0.68 0.83 0.73 63.00
187 INT163785 Positive_regulation of Transcription of Casp1 1 0.42 0.89 0.73 63.00
188 INT163782 Positive_regulation of Transcription of Nlrp1a 1 0.50 0.89 0.73 63.00
189 INT129856 Positive_regulation of TNFRSF11A 26 0.68 16.21 4.75 62.84
190 INT115889 Binding of Fas 27 0.36 28.87 4.08 62.16
191 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 62.08
192 INT89964 Negative_regulation of Transcription of Fas 3 0.58 2.62 0.06 60.80
193 INT89965 Transcription of Fas 5 0.71 5.28 1.45 60.28
194 INT200458 Positive_regulation of Tha1 3 0.15 0.78 0.03 60.28
195 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99 60.24
196 INT23598 Binding of SCN5A 32 0.40 16 5.35 59.76
197 INT34952 Regulation of ABAT 28 0.61 6.05 14.39 59.20
198 INT6852 Localization of TNF 883 0.81 705.95 270.84 59.12
199 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81 58.76
200 INT134946 Localization of GBA 3 0.75 2.49 0.24 58.56
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