D:Borna Disease

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pChart

Disease Term
Synonyms None
Documents 15
Hot Single Events 13
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Borna Disease. They are ordered first by their relevance to Borna Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT190868 Binding of Marcks and Ltp 1 0.01 0.87 0.81 50.00
2 INT190869 Binding of Prkca and Ltp 1 0.03 0.86 0.81 50.00
3 INT190867 Binding of Marcks and Prkca 1 0.17 0.8 0.77 50.00
4 INT190870 BDNF Positive_regulation of Phosphorylation of Mapk1 1 0.12 0.54 0.44 50.00
5 INT268110 PRKCA Positive_regulation of Phosphorylation of SNAP25 1 0.32 0.11 0.35 50.00
6 INT268111 Binding of MARCKS and SNAP25 1 0.09 0 0.05 50.00
7 INT228627 Nss1 Negative_regulation of Ifnar1 1 0.02 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Borna Disease. They are ordered first by their pain relevance and then by number of times they were reported in Borna Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2421 Positive_regulation of Positive_regulation of Penk 97 0.69 13.38 55.32 99.38
2 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 99.10
3 INT12347 Positive_regulation of Rent1 5 0.11 0.52 1 99.10
4 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 95.20
5 INT79805 Phosphorylation of PRKCA 57 0.81 23.33 20.41 93.68
6 INT120471 Phosphorylation of STMN1 3 0.01 0.97 1.2 93.68
7 INT106636 Binding of PRKCA 7 0.28 3.06 1.93 87.40
8 INT1711 Negative_regulation of Positive_regulation of Penk 54 0.59 6.55 32.42 86.80
9 INT132690 Negative_regulation of Positive_regulation of CA1 1 0.40 1.26 0.87 86.80
10 INT96164 Positive_regulation of CA1 8 0.67 10.99 6.23 84.12
11 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 83.20
12 INT80809 Gene_expression of STMN1 8 0.28 6.71 0.99 82.92
13 INT61172 Gene_expression of PRKCA 34 0.77 8.89 15.47 81.56
14 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04 79.92
15 INT166678 Negative_regulation of Phosphorylation of PRKCA 12 0.38 5.77 4.59 75.00
16 INT171682 Positive_regulation of Phosphorylation of PRKCA 3 0.43 1.04 2.72 75.00
17 INT120334 Negative_regulation of Phosphorylation of SNAP25 4 0.37 1.71 3.21 75.00
18 INT130439 Negative_regulation of Phosphorylation of MARCKS 2 0.19 1.03 0.94 75.00
19 INT120339 Phosphorylation of SNAP25 5 0.51 2.97 5.3 75.00
20 INT130441 Phosphorylation of MARCKS 8 0.37 3.24 3.09 75.00
21 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 50.00
22 INT95787 Positive_regulation of Mapk1 568 0.70 226.51 220.94 50.00
23 INT7628 Gene_expression of Ltp 273 0.77 70.21 147.87 50.00
24 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91 50.00
25 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66 50.00
26 INT15898 Positive_regulation of Prkaca 199 0.70 50.89 87.54 50.00
27 INT92434 Phosphorylation of Mapk1 287 0.82 91.65 83.46 50.00
28 INT13036 Positive_regulation of Positive_regulation of Ltp 105 0.51 23.71 77.66 50.00
29 INT53964 Negative_regulation of Prkaca 131 0.58 38.76 69.52 50.00
30 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97 50.00
31 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81 50.00
32 INT66383 Phosphorylation of Prkaca 143 0.80 30.85 43.38 50.00
33 INT92437 Positive_regulation of Phosphorylation of Mapk1 113 0.70 32.19 40.29 50.00
34 INT102611 Negative_regulation of Positive_regulation of Mapk1 74 0.58 35.57 39.37 50.00
35 INT64164 Regulation of Prkca 34 0.62 10.44 30.99 50.00
36 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43 50.00
37 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99 50.00
38 INT66381 Regulation of Prkaca 40 0.62 13.38 27.96 50.00
39 INT117527 Binding of Prkca 25 0.48 6.43 21.05 50.00
40 INT79458 Localization of Prkca 30 0.81 11.13 15.78 50.00
41 INT52714 Regulation of PRKCA 28 0.61 7.73 13.66 50.00
42 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36 50.00
43 INT67048 Gene_expression of ITGA4 58 0.75 28.93 10.16 50.00
44 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10 50.00
45 INT108931 Negative_regulation of BDNF 38 0.59 19.61 8.84 50.00
46 INT120335 Gene_expression of SNAP25 24 0.65 9.44 5.83 50.00
47 INT123045 Negative_regulation of Phosphorylation of Prkca 9 0.46 5.73 5.77 50.00
48 INT57441 Positive_regulation of Phosphorylation of Prkca 9 0.40 2.72 4.89 50.00
49 INT106553 Positive_regulation of Positive_regulation of Bdnf 11 0.43 5.35 4.07 50.00
50 INT190858 Phosphorylation of Marcks 1 0.33 6.29 3.86 50.00
51 INT113924 Binding of Mapk1 27 0.38 8.64 3.84 50.00
52 INT83206 Regulation of Regulation of Prkca 3 0.45 1.34 3.46 50.00
53 INT118153 Regulation of Positive_regulation of Prkca 5 0.45 3.15 3.23 50.00
54 INT171368 Regulation of Phosphorylation of Mapk1 14 0.61 4.77 3.14 50.00
55 INT190860 Regulation of Localization of Prkca 4 0.21 1.61 3.11 50.00
56 INT126567 Positive_regulation of Positive_regulation of BDNF 8 0.59 6.16 3.06 50.00
57 INT190863 Negative_regulation of Phosphorylation of Marcks 1 0.23 4.71 2.47 50.00
58 INT101582 Negative_regulation of SNAP25 9 0.57 4.34 2.12 50.00
59 INT115303 Localization of SNAP25 8 0.73 1.43 1.82 50.00
60 INT89639 Phosphorylation of CAMK2G 5 0.48 0.66 1.78 50.00
61 INT79569 Protein_catabolism of PRKCA 3 1.00 0.44 1.78 50.00
62 INT151790 Binding of SNAP25 11 0.24 1.09 1.73 50.00
63 INT24238 Phosphorylation of Syn1 11 0.45 2.97 1.65 50.00
64 INT52713 Regulation of Negative_regulation of PRKCA 5 0.36 1.23 1.41 50.00
65 INT45155 Negative_regulation of Polymerase 18 0.51 15.18 1.38 50.00
66 INT190844 Phosphorylation of Stxbp1 1 0.80 1.54 1.3 50.00
67 INT190865 Positive_regulation of Phosphorylation of Marcks 1 0.20 1.79 1.28 50.00
68 INT220763 Regulation of Phosphorylation of PRKCA 3 0.29 0.84 1.22 50.00
69 INT120337 Positive_regulation of Phosphorylation of SNAP25 2 0.29 0.11 1.19 50.00
70 INT125060 Phosphorylation of Ppp1r17 2 0.01 2.14 1.18 50.00
71 INT115304 Regulation of SNAP25 7 0.60 1.24 0.95 50.00
72 INT190843 Negative_regulation of Phosphorylation of Stxbp1 1 0.57 0.83 0.69 50.00
73 INT190855 Phosphorylation of Pis1 1 0.80 0.96 0.66 50.00
74 INT189347 Phosphorylation of CSNK2A1 4 0.11 1.62 0.57 50.00
75 INT190864 Positive_regulation of Phosphorylation of Tbk1 1 0.08 0.68 0.53 50.00
76 INT190859 Phosphorylation of Tbk1 1 0.12 0.68 0.52 50.00
77 INT200435 Binding of polymerase 6 0.16 5.56 0.47 50.00
78 INT190866 Phosphorylation of Camk2d 1 0.13 0.05 0.4 50.00
79 INT268126 Phosphorylation of OCA2 1 0.02 1.07 0.33 50.00
80 INT268130 Regulation of Phosphorylation of SNAP25 1 0.28 0.07 0.32 50.00
81 INT268131 Gene_expression of MARCKS 3 0.27 1.09 0.31 50.00
82 INT268125 Positive_regulation of Negative_regulation of polymerase 1 0.02 0.47 0.26 50.00
83 INT190857 Negative_regulation of Phosphorylation of Ppp1r17 1 0.00 0.85 0.21 50.00
84 INT268108 Phosphorylation of Bdv1 1 0.01 1.1 0.2 50.00
85 INT268109 Regulation of Phosphorylation of Bdv1 1 0.00 0.57 0.1 50.00
86 INT268124 Regulation of Binding of 1 0.02 0.53 0.08 50.00
87 INT190854 Binding of Marcks 1 0.12 0.09 0.08 50.00
88 INT190861 Binding of Syt1 1 0.03 0.55 0.08 50.00
89 INT268127 Binding of MARCKS 2 0.14 0 0.05 50.00
90 INT268128 Gene_expression of TPR 1 0.01 1.2 0.04 50.00
91 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
92 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 5.00
93 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
94 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
95 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 5.00
96 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 5.00
97 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
98 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
99 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 5.00
100 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 5.00
101 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 5.00
102 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 5.00
103 INT134651 Binding of TLR4 89 0.48 66.96 23.19 5.00
104 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 5.00
105 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62 5.00
106 INT53080 Positive_regulation of Ptgs1 42 0.42 23.58 14.37 5.00
107 INT137614 Gene_expression of Lgals3 70 0.77 66.13 12.53 5.00
108 INT178306 Negative_regulation of Gene_expression of Gopc 71 0.37 26.43 9.74 5.00
109 INT52442 Binding of Ptgs1 16 0.35 9.05 8.78 5.00
110 INT50290 Binding of Cpox 29 0.27 17.19 8.01 5.00
111 INT101189 Transcription of Gtf3a 49 0.17 24.39 7.93 5.00
112 INT183681 Positive_regulation of Tlr3 20 0.62 16.25 4.54 5.00
113 INT158596 Binding of Tlr3 24 0.47 11.66 3.69 5.00
114 INT1683 Gene_expression of Cux1 20 0.58 6.29 3.59 5.00
115 INT59342 Negative_regulation of NPC1 20 0.44 20.21 2.79 5.00
116 INT70197 Negative_regulation of Positive_regulation of Ptgs1 6 0.24 2.61 2.44 5.00
117 INT78005 Negative_regulation of Binding of Cpox 7 0.31 3.19 1.7 5.00
118 INT89209 Negative_regulation of Binding of Ptgs1 6 0.06 2.7 1.39 5.00
119 INT328226 Negative_regulation of Positive_regulation of Cpox 3 0.11 1.49 0.73 5.00
120 INT293942 Negative_regulation of Gene_expression of Cux1 3 0.34 0.97 0.31 5.00
121 INT293946 Positive_regulation of Gene_expression of Cux1 2 0.40 0.65 0.31 5.00
122 INT254194 Regulation of Positive_regulation of Tlr3 2 0.52 0.79 0.19 5.00
123 INT310483 Positive_regulation of Eomes 2 0.38 0.85 0.19 5.00
124 INT185254 Gene_expression of Pax6 14 0.72 1.77 0.16 5.00
125 INT336418 Negative_regulation of Binding of Tlr3 1 0.36 0.59 0.16 5.00
126 INT10462 Gene_expression of Tcrb 7 0.65 2.34 0.13 5.00
127 INT170377 Gene_expression of Eomes 2 0.42 0.37 0.03 5.00
128 INT336419 Negative_regulation of Gene_expression of Pax6 1 0.45 0.12 0.03 5.00
129 INT336415 Positive_regulation of Gene_expression of Eomes 1 0.38 0.17 0.03 5.00
130 INT206481 Transcription of Pax6 2 0.41 0.19 0.03 5.00
131 INT336414 Transcription of Cux1 1 0.47 0.23 0.03 5.00
132 INT336412 Negative_regulation of Gene_expression of Eomes 1 0.23 0.11 0 5.00
133 INT336416 Binding of Pax6 1 0.28 0 0 5.00
134 INT336420 Positive_regulation of Binding of Pax6 1 0.38 0 0 5.00
135 INT336411 Gene_expression of Olfr140 1 0.00 0.15 0 5.00
136 INT336413 Negative_regulation of Eomes 1 0.32 0.11 0 5.00
137 INT291889 Negative_regulation of Pax6 2 0.45 0.39 0 5.00
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