D:Brain Stem Infarctions

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Disease Term
Synonyms BENEDICT SYNDROME, Brain Stem Infarction, BRAINSTEM INFARCTION, Brainstem Infarctions, Brainstem Stroke, CLAUDE SYNDROME, Foville Syndrome, Infarction Brain Stem, Infarction Brainstem, Infarctions Brain Stem, Infarctions Brainstem
Documents 147
Hot Single Events 5
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Brain Stem Infarctions. They are ordered first by their relevance to Brain Stem Infarctions and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT304776 Binding of KMS and KTWS 1 0.01 2.24 0 100.00
2 INT310186 Binding of Gdf2 and Bmpr2 1 0.02 0 0 13.12
3 INT310189 Binding of Acvrl1 and Gdf2 1 0.01 0 0 13.12
4 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19 5.00
5 INT275667 Binding of CYP1B1 and GLC3C 1 0.27 0.99 0 5.00
6 INT310191 Flt3 Positive_regulation of Gene_expression of Id1 1 0.03 0.81 0 5.00
7 INT310188 Binding of Adcyap1r1 and Smad7 1 0.00 0 0 5.00
8 INT310187 Acvrl1 Regulation of Gene_expression of Bmpr2 1 0.04 0 0 5.00
9 INT310190 Binding of Adcyap1r1 and Smad6 1 0.00 0 0 5.00
10 INT310192 Tgfbr1 Positive_regulation of Regulation of Acvrl1 1 0.01 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Brain Stem Infarctions. They are ordered first by their pain relevance and then by number of times they were reported in Brain Stem Infarctions. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT162783 Binding of LIFR 1 0.36 1.52 0.86 100.00
2 INT156294 Binding of Hm 2 0.07 1.7 0.86 100.00
3 INT33039 Regulation of Ptcra 3 0.04 1.16 0.37 99.72
4 INT139738 Gene_expression of Ptcra 9 0.63 2.75 1.14 97.76
5 INT262004 Negative_regulation of CYP1B1 4 0.59 3.24 0 87.44
6 INT147584 Localization of AIS 38 0.63 12.83 5.27 76.56
7 INT25402 Binding of Ptcra 10 0.34 3.54 1.85 76.08
8 INT163405 Positive_regulation of Binding of ROS1 15 0.27 9.39 2.58 69.44
9 INT94784 Binding of ROS1 113 0.40 71.57 10.26 68.92
10 INT121861 Regulation of BID 4 0.31 2.73 1.15 68.32
11 INT262003 Binding of CYP1B1 3 0.48 3.34 0 66.88
12 INT1252 Binding of Ache 46 0.48 9.94 10.25 62.56
13 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15 62.48
14 INT310167 Gene_expression of Acvrl1 2 0.40 5.47 1.4 62.48
15 INT334369 Negative_regulation of Sctr 1 0.00 1.45 0.39 55.76
16 INT34682 Binding of ACSM3 1 0.47 0.99 0.17 55.44
17 INT265328 Positive_regulation of Acvrl1 5 0.40 3.18 0.78 51.76
18 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 48.64
19 INT310174 Positive_regulation of Smad1 9 0.45 2.16 0.14 43.32
20 INT334368 Negative_regulation of Positive_regulation of Sctr 1 0.00 0.41 0.1 43.16
21 INT334370 Positive_regulation of Sctr 1 0.00 0.4 0.1 41.92
22 INT203465 Negative_regulation of Id1 2 0.06 0.68 0 34.96
23 INT289718 Positive_regulation of BPPV 1 0.35 1.31 0.1 26.16
24 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67 25.16
25 INT310179 Positive_regulation of Positive_regulation of Tgfbr1 1 0.08 0 0 23.84
26 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87 23.40
27 INT38564 Binding of AIS 36 0.38 27.77 9.31 17.36
28 INT90938 Gene_expression of Eng 48 0.72 15.76 1.24 16.48
29 INT96885 Localization of CYP1B1 4 0.80 2.11 0.23 15.16
30 INT263541 Localization of MYOC 3 0.75 1.97 0.08 14.72
31 INT310181 Binding of Gdf2 1 0.04 0 0 13.12
32 INT310163 Positive_regulation of Positive_regulation of Acvrl1 1 0.08 0 0 8.12
33 INT81982 Gene_expression of Bmpr2 36 0.60 14.58 1.55 5.68
34 INT254332 Negative_regulation of Gene_expression of Bmpr2 3 0.22 2.41 0.07 5.68
35 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
36 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 5.00
37 INT4768 Positive_regulation of OPRM1 212 0.70 31.09 164.28 5.00
38 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
39 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57 5.00
40 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 5.00
41 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
42 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 5.00
43 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
44 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
45 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
46 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
47 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
48 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89 5.00
49 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 5.00
50 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61 5.00
51 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42 5.00
52 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 5.00
53 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
54 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 5.00
55 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92 5.00
56 INT20632 Gene_expression of TNC 72 0.78 30.43 13.16 5.00
57 INT15246 Regulation of FOS 32 0.60 15.34 12.94 5.00
58 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 5.00
59 INT46695 Positive_regulation of TNC 28 0.67 17.06 12.04 5.00
60 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69 5.00
61 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18 5.00
62 INT109005 Gene_expression of Proc 61 0.75 37.86 8.49 5.00
63 INT54368 Positive_regulation of VTA1 13 0.59 3.81 8.13 5.00
64 INT121815 Regulation of Positive_regulation of OPRM1 7 0.62 0.75 7.36 5.00
65 INT86867 Regulation of CREB1 15 0.46 4.95 7.28 5.00
66 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27 5.00
67 INT30443 Positive_regulation of AIS 30 0.54 22.59 7.2 5.00
68 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 5.00
69 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 5.00
70 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88 5.00
71 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84 5.00
72 INT52512 Positive_regulation of SLC43A3 21 0.41 5.39 5.27 5.00
73 INT60585 Regulation of TP53 59 0.59 54.55 5.21 5.00
74 INT22825 Regulation of Gtf3a 36 0.25 19.93 5.03 5.00
75 INT140350 Binding of C2 17 0.36 3.97 4.69 5.00
76 INT96504 Negative_regulation of SLC18A2 5 0.36 2.07 4.62 5.00
77 INT3128 Negative_regulation of PON1 30 0.59 26.19 4.57 5.00
78 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22 5.00
79 INT44578 Binding of Hbb 19 0.48 3.12 4.2 5.00
80 INT3530 Regulation of BCHE 18 0.60 5.47 4.12 5.00
81 INT183560 Binding of GABRB3 12 0.23 2.59 3.77 5.00
82 INT75485 Gene_expression of Tgfbr2 10 0.57 10.98 3.76 5.00
83 INT179826 Gene_expression of Il11 29 0.75 11.5 3.75 5.00
84 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69 5.00
85 INT90823 Positive_regulation of Ptpn2 25 0.59 22.97 3.59 5.00
86 INT232667 Binding of Pd 17 0.16 20.76 3.58 5.00
87 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3 5.00
88 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25 5.00
89 INT178457 Positive_regulation of LIFR 12 0.56 3.98 2.9 5.00
90 INT14447 Localization of F2 20 0.79 12.77 2.67 5.00
91 INT164645 Binding of Csi 9 0.48 4.6 2.46 5.00
92 INT204019 Negative_regulation of C2 10 0.26 6.23 2.44 5.00
93 INT56084 Negative_regulation of SLC43A3 11 0.39 5.39 2.27 5.00
94 INT33170 Binding of Chrm1 11 0.48 1.58 2.1 5.00
95 INT172559 Localization of Proc 16 0.02 21.49 2.08 5.00
96 INT57115 Negative_regulation of NT5E 8 0.57 4.35 2.03 5.00
97 INT53998 Positive_regulation of MAOB 8 0.61 1.22 2 5.00
98 INT30531 Gene_expression of C2 15 0.66 5.5 1.99 5.00
99 INT258135 Gene_expression of CARTPT 3 0.40 5.25 1.88 5.00
100 INT10498 Positive_regulation of Tcn2 7 0.19 1.76 1.87 5.00
101 INT112648 Positive_regulation of Fn1 19 0.49 13.73 1.66 5.00
102 INT2847 Positive_regulation of Negative_regulation of Ache 8 0.49 1.09 1.65 5.00
103 INT137281 Regulation of Csi 15 0.39 1.2 1.56 5.00
104 INT72138 Gene_expression of Pthlh 18 0.75 17.68 1.49 5.00
105 INT199550 Negative_regulation of Flt1 18 0.37 12.57 1.37 5.00
106 INT164205 Binding of Proc 12 0.36 12.31 1.19 5.00
107 INT96034 Negative_regulation of Proc 11 0.33 10.21 1.18 5.00
108 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17 5.00
109 INT27536 Gene_expression of Caf 4 0.52 0.41 1.13 5.00
110 INT96873 Gene_expression of CYP1B1 28 0.78 11.81 1.09 5.00
111 INT74166 Positive_regulation of C2 10 0.55 2.83 1.05 5.00
112 INT290265 Positive_regulation of FAT1 11 0.67 5.93 0.91 5.00
113 INT27188 Negative_regulation of Tcn2 5 0.18 1.33 0.83 5.00
114 INT157382 Gene_expression of Csi 17 0.58 3.93 0.82 5.00
115 INT271160 Negative_regulation of SYNE1 1 0.00 0.67 0.81 5.00
116 INT72334 Negative_regulation of LRP5 7 0.35 1.71 0.81 5.00
117 INT96879 Positive_regulation of CYP1B1 14 0.70 5.73 0.78 5.00
118 INT69419 Binding of BPPV 5 0.32 7.9 0.7 5.00
119 INT231558 Regulation of LRP5 2 0.24 1.02 0.68 5.00
120 INT100294 Positive_regulation of Gene_expression of Bmp7 8 0.46 5.41 0.61 5.00
121 INT69782 Gene_expression of MYOC 12 0.78 8.44 0.61 5.00
122 INT142827 Regulation of Gene_expression of CREB1 3 0.61 0.39 0.61 5.00
123 INT255313 Positive_regulation of Positive_regulation of AIS 2 0.04 3.83 0.55 5.00
124 INT271161 Negative_regulation of Negative_regulation of SYNE1 1 0.00 0.24 0.47 5.00
125 INT289719 Gene_expression of BPPV 2 0.51 2.96 0.47 5.00
126 INT251661 Phosphorylation of NT5E 2 0.21 1.59 0.46 5.00
127 INT251659 Positive_regulation of Prdx6 2 0.11 2.07 0.36 5.00
128 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34 5.00
129 INT92100 Binding of Smad4 5 0.31 2.23 0.3 5.00
130 INT105007 Binding of MOXD1 2 0.03 1.15 0.29 5.00
131 INT81981 Negative_regulation of Bmpr2 4 0.27 2.88 0.21 5.00
132 INT69784 Binding of MYOC 8 0.48 5.67 0.21 5.00
133 INT96887 Regulation of Gene_expression of CYP1B1 2 0.45 0.9 0.2 5.00
134 INT125773 Transcription of Serpine1 4 0.53 2.35 0.19 5.00
135 INT251660 Positive_regulation of Positive_regulation of Prdx6 1 0.04 0.09 0.17 5.00
136 INT347937 Regulation of Binding of C2 1 0.03 0.31 0.12 5.00
137 INT289720 Positive_regulation of Gene_expression of BPPV 1 0.35 1.63 0.1 5.00
138 INT201962 Transcription of Bmpr2 6 0.37 3.51 0.09 5.00
139 INT251664 Positive_regulation of PSG1 1 0.08 0.37 0.05 5.00
140 INT148819 Positive_regulation of Positive_regulation of TNC 4 0.45 0.53 0.05 5.00
141 INT251662 Gene_expression of PSG1 1 0.10 0.38 0.05 5.00
142 INT251663 Regulation of PSG1 1 0.02 0.39 0.05 5.00
143 INT320464 Regulation of MYOC 1 0.34 1 0 5.00
144 INT310166 Regulation of Acvrl1 1 0.07 0 0 5.00
145 INT310169 Gene_expression of Bmp10 1 0.14 0.48 0 5.00
146 INT320463 Transcription of CYP1B1 1 0.68 0.14 0 5.00
147 INT310177 Binding of Tgfbr2 1 0.24 0 0 5.00
148 INT310171 Phosphorylation of Eng 1 0.24 0.5 0 5.00
149 INT310172 Positive_regulation of Transcription of Serpine1 1 0.18 1.99 0 5.00
150 INT262005 Regulation of CYP1B1 4 0.62 4.52 0 5.00
151 INT310178 Negative_regulation of Transcription of Serpine1 1 0.15 0.98 0 5.00
152 INT310165 Negative_regulation of Transcription of Bmpr2 1 0.22 2.1 0 5.00
153 INT310168 Phosphorylation of Tgfbr2 1 0.41 1.5 0 5.00
154 INT310182 Gene_expression of Gdf2 1 0.06 0.48 0 5.00
155 INT265340 Binding of Acvrl1 3 0.30 0.46 0 5.00
156 INT310176 Localization of Tgfbr1 1 0.11 0.83 0 5.00
157 INT265326 Regulation of Tgfbr1 2 0.43 0.17 0 5.00
158 INT310162 Gene_expression of Id1 1 0.10 1.45 0 5.00
159 INT310173 Binding of Smad6 1 0.05 0 0 5.00
160 INT310175 Binding of Adcyap1r1 1 0.02 0 0 5.00
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