D:Budd-chiari Syndrome

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Budd Chiari Syndrome, Chiari S Syndrome, Chiari Syndrome, CHIARIS SYNDROME, Hepatic Vein Thromboses, HEPATIC VEIN THROMBOSIS, Hepatic Venous Outflow Obstruction, THROMBOSES HEPATIC VEIN, Thrombosis Hepatic Vein, VEIN THROMBOSES HEPATIC, Vein Thrombosis Hepatic
Documents 148
Hot Single Events 20
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Budd-chiari Syndrome. They are ordered first by their relevance to Budd-chiari Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT301082 Binding of BCS1L and TARM1 1 0.17 1.21 0 100.00
2 INT301083 Binding of BCS1L and MYH7 1 0.36 1.53 0.19 100.00
3 INT312304 Binding of JAK2 and VEGFA 1 0.30 0.82 0 73.52
4 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
5 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 5.00
6 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
7 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
8 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1 5.00
9 INT279286 Binding of TXK and VEGFA 3 0.05 2.35 0.07 5.00
10 INT279284 TXK Regulation of KDR 3 0.05 2.22 0.04 5.00
11 INT312303 Positive_regulation of FLT1 Positive_regulation of VEGFA 1 0.38 0.73 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Budd-chiari Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Budd-chiari Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT119271 Positive_regulation of BCS1L 13 0.50 7.56 0.39 100.00
2 INT80784 Regulation of BCS1L 9 0.39 7.63 1.47 100.00
3 INT144766 Binding of BCS1L 11 0.32 8.2 0.13 100.00
4 INT121788 Localization of BCS1L 11 0.73 10.16 1.14 100.00
5 INT84180 Binding of F5 22 0.48 18.6 0.49 99.98
6 INT192426 Gene_expression of TARM1 3 0.33 1.98 0 99.84
7 INT192423 Positive_regulation of TARM1 5 0.34 10.77 0.51 99.82
8 INT41314 Gene_expression of GGTLC1 9 0.59 5.61 1.79 99.68
9 INT224924 Binding of TARM1 4 0.18 3.42 0.39 98.36
10 INT10140 Negative_regulation of ANXA3 4 0.07 6.07 0.62 93.92
11 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4 92.04
12 INT35584 Binding of ACLY 22 0.35 31.78 7.17 91.76
13 INT23045 Positive_regulation of Hbb 31 0.64 19.35 4.54 90.08
14 INT32709 Negative_regulation of Hbb 30 0.54 18.27 6.97 88.32
15 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 86.68
16 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 83.80
17 INT6810 Gene_expression of ENO2 70 0.78 54.8 8.35 83.80
18 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 83.80
19 INT15652 Positive_regulation of ENO2 37 0.68 33.39 5.02 83.80
20 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 81.00
21 INT81206 Binding of ENPEP 11 0.47 5.19 0.88 78.28
22 INT249060 Localization of FGF14 1 0.37 2.67 0.03 75.96
23 INT249058 Positive_regulation of FGF14 1 0.23 2.67 0.03 75.96
24 INT249057 Gene_expression of FGF14 1 0.33 3.44 0.04 64.04
25 INT259036 Transcription of SH2B2 2 0.55 7.01 1.46 55.64
26 INT301086 Negative_regulation of TARM1 1 0.21 0.53 0.04 54.80
27 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16 54.56
28 INT259032 Binding of PEX1 2 0.01 4.67 0.15 52.40
29 INT332162 Phosphorylation of Dck 1 0.04 0.59 0.22 50.88
30 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 50.16
31 INT157846 Gene_expression of BCS1L 13 0.50 15.89 0.83 50.00
32 INT92680 Gene_expression of Fgf2 59 0.77 28.11 8.12 47.68
33 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 46.96
34 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56 46.72
35 INT168000 Protein_catabolism of F2 6 0.63 2.19 0.63 44.64
36 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 40.40
37 INT17747 Regulation of Cd4 14 0.41 10.02 2.12 31.00
38 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 25.00
39 INT195206 Binding of BCC1 15 0.41 21.3 0.62 16.44
40 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69 11.36
41 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 8.52
42 INT175260 Negative_regulation of Gene_expression of SH2B2 2 0.25 4.41 0.21 8.52
43 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 7.64
44 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
45 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
46 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
47 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
48 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
49 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
50 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
51 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
52 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
53 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
54 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
55 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
56 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
57 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
58 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
59 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58 5.00
60 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
61 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
62 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 5.00
63 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 5.00
64 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
65 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
66 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 5.00
67 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
68 INT756 Gene_expression of C3 138 0.75 100.6 19.2 5.00
69 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 5.00
70 INT18672 Gene_expression of Ncam1 54 0.78 36.64 18.79 5.00
71 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 5.00
72 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
73 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 5.00
74 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 5.00
75 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17 5.00
76 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 5.00
77 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 5.00
78 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 5.00
79 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 5.00
80 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 5.00
81 INT110178 Phosphorylation of MAPK14 40 0.68 19.38 10.37 5.00
82 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 5.00
83 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 5.00
84 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 5.00
85 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 5.00
86 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41 5.00
87 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 5.00
88 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75 5.00
89 INT22450 Gene_expression of GPI 31 0.58 18.77 6.71 5.00
90 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51 5.00
91 INT86805 Localization of HGF 49 0.71 28.48 6.35 5.00
92 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 5.00
93 INT69153 Positive_regulation of Gene_expression of IL5 22 0.32 23.59 5.7 5.00
94 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68 5.00
95 INT28084 Positive_regulation of VIM 49 0.67 35.12 5.15 5.00
96 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 5.00
97 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79 5.00
98 INT37661 Negative_regulation of SERPINC1 48 0.59 38.6 4.77 5.00
99 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69 5.00
100 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38 5.00
101 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3 5.00
102 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22 5.00
103 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14 5.00
104 INT68269 Gene_expression of CD99 49 0.77 47.38 3.86 5.00
105 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 5.00
106 INT168003 Localization of Fgf2 24 0.80 12.52 3.31 5.00
107 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 5.00
108 INT78297 Gene_expression of CD59 31 0.72 24.11 3.18 5.00
109 INT58756 Binding of GPI 10 0.48 7.17 3 5.00
110 INT61791 Positive_regulation of SH2B2 9 0.50 8.36 2.99 5.00
111 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88 5.00
112 INT209501 Gene_expression of CADPS 15 0.65 20.7 2.22 5.00
113 INT9254 Negative_regulation of LDHA 23 0.43 13.3 2.2 5.00
114 INT137690 Negative_regulation of Gene_expression of Ncam1 3 0.50 3.37 2.18 5.00
115 INT11183 Negative_regulation of SH2B2 4 0.34 6.99 2.12 5.00
116 INT3179 Positive_regulation of SCT 15 0.50 4.79 1.98 5.00
117 INT130364 Positive_regulation of Thbs1 7 0.62 7.73 1.97 5.00
118 INT16385 Regulation of C3 20 0.41 9.98 1.92 5.00
119 INT143127 Positive_regulation of FLT1 44 0.66 21.7 1.92 5.00
120 INT183753 Regulation of HBM 24 0.39 13.13 1.79 5.00
121 INT62712 Negative_regulation of HGF 19 0.58 7.21 1.67 5.00
122 INT29777 Negative_regulation of CD59 16 0.42 14.88 1.56 5.00
123 INT182297 Positive_regulation of Phosphorylation of MAPK14 7 0.42 3.36 1.53 5.00
124 INT143443 Localization of HIF1A 14 0.78 10.93 1.49 5.00
125 INT12035 Regulation of F2 21 0.45 12.66 1.47 5.00
126 INT119520 Gene_expression of TXK 19 0.19 17.54 1.45 5.00
127 INT147788 Regulation of FUT1 11 0.12 7.72 1.44 5.00
128 INT39444 Negative_regulation of Positive_regulation of F2 7 0.59 5.82 1.42 5.00
129 INT181868 Localization of ACLY 5 0.62 6.36 1.4 5.00
130 INT134338 Gene_expression of CD55 23 0.65 13.01 1.38 5.00
131 INT236277 Positive_regulation of Gene_expression of CADPS 5 0.42 9.17 1.29 5.00
132 INT31572 Negative_regulation of FLT1 21 0.48 16.49 1.18 5.00
133 INT57689 Localization of CD59 7 0.78 4.51 1.17 5.00
134 INT209503 Positive_regulation of CADPS 3 0.42 7 1.11 5.00
135 INT116512 Gene_expression of MVD 4 0.75 1.61 1.06 5.00
136 INT102249 Binding of HIF1A 39 0.36 30.47 1.04 5.00
137 INT37687 Binding of PLAUR 8 0.29 3.61 1.03 5.00
138 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99 5.00
139 INT134341 Negative_regulation of CD55 12 0.58 10.06 0.95 5.00
140 INT7351 Gene_expression of NPS 5 0.58 1.87 0.88 5.00
141 INT35292 Negative_regulation of C5 7 0.43 5.3 0.86 5.00
142 INT2608 Localization of GPI 7 0.73 4.53 0.85 5.00
143 INT173100 Binding of KDR 39 0.39 22.48 0.81 5.00
144 INT79034 Negative_regulation of GPI 7 0.58 3.94 0.66 5.00
145 INT117145 Negative_regulation of Gene_expression of Thbs1 11 0.43 5.67 0.57 5.00
146 INT160852 Regulation of CD55 5 0.16 5.28 0.56 5.00
147 INT52740 Binding of ACLS 5 0.31 3 0.54 5.00
148 INT143125 Binding of FLT1 48 0.40 13.6 0.51 5.00
149 INT277912 Positive_regulation of Gene_expression of CD59 2 0.19 2.76 0.49 5.00
150 INT81965 Gene_expression of F5 16 0.65 13.29 0.48 5.00
151 INT45111 Gene_expression of PRB1 15 0.58 4.16 0.47 5.00
152 INT149861 Gene_expression of CD52 14 0.75 9.35 0.47 5.00
153 INT259035 Localization of SH2B2 3 0.43 1.77 0.42 5.00
154 INT145854 Gene_expression of Jak2 4 0.67 3.08 0.41 5.00
155 INT207081 Binding of Plaur 6 0.31 5.99 0.41 5.00
156 INT117662 Gene_expression of ABL1 21 0.69 18.76 0.39 5.00
157 INT148797 Phosphorylation of KDR 7 0.80 5.15 0.36 5.00
158 INT259031 Negative_regulation of Gene_expression of CADPS 1 0.07 3.04 0.35 5.00
159 INT152353 Binding of Evl 3 0.42 2.01 0.33 5.00
160 INT283244 Gene_expression of Pgf 7 0.52 2.41 0.32 5.00
161 INT179687 Negative_regulation of Gene_expression of KDR 6 0.22 5.37 0.31 5.00
162 INT173097 Localization of KDR 20 0.73 12.73 0.31 5.00
163 INT309915 Negative_regulation of F2RL3 2 0.01 2.06 0.27 5.00
164 INT17009 Regulation of CADPS 2 0.08 1.97 0.24 5.00
165 INT210391 Negative_regulation of FUT1 5 0.20 5.51 0.23 5.00
166 INT180264 Positive_regulation of BCC1 11 0.59 12.81 0.2 5.00
167 INT175035 Gene_expression of Mecom 11 0.65 10.1 0.19 5.00
168 INT312302 Gene_expression of Prss27 2 0.02 3.95 0.19 5.00
169 INT157725 Gene_expression of ACLS 2 0.13 2.89 0.17 5.00
170 INT259033 Gene_expression of LCA5L 1 0.01 2.71 0.16 5.00
171 INT180265 Localization of BCC1 7 0.65 9.48 0.15 5.00
172 INT284765 Gene_expression of BCC1 22 0.56 29.32 0.14 5.00
173 INT197103 Binding of FLT4 2 0.29 3.08 0.14 5.00
174 INT249059 Binding of FGF14 1 0.20 2.3 0.13 5.00
175 INT229956 Binding of CD59 4 0.23 1.35 0.13 5.00
176 INT259037 Negative_regulation of Binding of ACLY 1 0.07 1.54 0.13 5.00
177 INT277914 Positive_regulation of Negative_regulation of CD59 1 0.11 1.01 0.12 5.00
178 INT265803 Positive_regulation of Positive_regulation of FLT1 5 0.41 2.85 0.1 5.00
179 INT165978 Localization of CD55 5 0.60 1.78 0.1 5.00
180 INT354483 Gene_expression of Evl 1 0.49 1.92 0.1 5.00
181 INT224335 Negative_regulation of Phosphorylation of KDR 5 0.35 5.24 0.09 5.00
182 INT259038 Negative_regulation of Positive_regulation of SH2B2 1 0.25 1.83 0.09 5.00
183 INT151948 Positive_regulation of Gene_expression of MVD 2 0.49 1.35 0.09 5.00
184 INT259039 Positive_regulation of Binding of ACLY 1 0.09 1.85 0.09 5.00
185 INT259030 Negative_regulation of Gene_expression of ACLY 1 0.07 1.95 0.08 5.00
186 INT198034 Positive_regulation of Localization of KDR 3 0.29 2.17 0.05 5.00
187 INT189580 Positive_regulation of Gene_expression of KDR 9 0.49 5.9 0.05 5.00
188 INT259040 Phosphorylation of SH2B2 1 0.47 0.85 0.03 5.00
189 INT259029 Regulation of Phosphorylation of SH2B2 1 0.26 0.85 0.03 5.00
190 INT309533 Negative_regulation of BCC1 3 0.25 2.62 0.03 5.00
191 INT312307 Positive_regulation of Regulation of HBM 2 0.01 1.94 0.03 5.00
192 INT354484 Negative_regulation of Evl 1 0.31 3.86 0 5.00
193 INT277909 Negative_regulation of Gene_expression of PIGA 1 0.41 1.17 0 5.00
194 INT66823 Positive_regulation of PIGA 2 0.49 2.83 0 5.00
195 INT354486 Negative_regulation of Positive_regulation of Evl 1 0.31 1.95 0 5.00
196 INT277911 Gene_expression of PIGA 1 0.65 1.16 0 5.00
197 INT354485 Positive_regulation of Evl 1 0.36 1.72 0 5.00
198 INT202420 Transcription of Jak2 1 0.56 0.91 0 5.00
199 INT312299 Positive_regulation of Gene_expression of Mecom 1 0.03 1.9 0 5.00
200 INT277913 Regulation of PIGA 1 0.60 0.49 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox