D:Bullous Skin Disease

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Disease Term
Synonyms ACQUIRED EPIDERMOLYSIS BULLOSA, BENIGN CICATRICIAL PEMPHIGOID, Benign Mucosal Pemphigoid, Bullous Contact Dermatitis, BULLOUS DERMATITIS NOS, BULLOUS DERMATOSES, Bullous Dermatosis, Bullous Disorder, BULLOUS DISORDERS, Bullous Pemphigoid, Bullous Skin Diseases
Documents 463
Hot Single Events 200
Hot Interactions 35

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Bullous Skin Disease. They are ordered first by their relevance to Bullous Skin Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT320769 Atp11c Regulation of Dsg1a 1 0.05 5.87 0 100.00
2 INT235016 IgG Negative_regulation of Binding of DSG1 1 0.04 2.89 0 100.00
3 INT234979 IgG Negative_regulation of Binding of Dsg3 1 0.06 1.59 0 100.00
4 INT320771 Atp11c Regulation of Localization of Dsg1a 1 0.03 1.46 0 100.00
5 INT235000 IgG Negative_regulation of DSG1 1 0.04 0.86 0 100.00
6 INT354789 Tnc Regulation of HSPG2 1 0.02 1.38 0 100.00
7 INT235010 Positive_regulation of Positive_regulation of SRC 1 0.01 0.84 0.05 100.00
8 INT235006 IgG Positive_regulation of SRC 1 0.01 0.82 0.05 100.00
9 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88 100.00
10 INT234989 IgG Positive_regulation of Positive_regulation of Car2 1 0.01 0.98 0 99.98
11 INT320767 Atp11c Negative_regulation of Dsg1a 1 0.05 1.71 0 99.98
12 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06 99.98
13 INT234988 Negative_regulation of Binding of Dsg3 and IgG 1 0.04 0.83 0 99.98
14 INT234967 Binding of Dsg3 and IgG 1 0.03 0.83 0 99.98
15 INT234972 IgG Positive_regulation of Gene_expression of Dsg3 1 0.05 0.8 0 99.98
16 INT234999 IgG Positive_regulation of Gene_expression of DSG1 1 0.05 0.8 0 99.98
17 INT234983 IgG Positive_regulation of Protein_catabolism of Jup 1 0.03 0.61 0 99.98
18 INT234969 Jup Regulation of Gene_expression of Dsp 1 0.01 0.54 0 99.70
19 INT235008 Binding of DSG1 and Dsg3 1 0.11 4.82 0 99.50
20 INT235009 Binding of DSG1 and Cdh1 1 0.02 0.87 0 99.22
21 INT235002 Negative_regulation of Binding of DSG1 and Dsg3 1 0.13 1.08 0 97.80
22 INT320768 Spp1 Regulation of Protein_catabolism of Dsg1a 1 0.08 0.77 0.11 96.44
23 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26 96.28
24 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26 96.28
25 INT234994 Binding of NKS1 and Dsg3 1 0.00 0.5 0.04 95.36
26 INT320770 Dsg2 Positive_regulation of Stat3 1 0.28 0.74 0.13 92.32
27 INT320765 Dsg2 Positive_regulation of Akt1 1 0.48 0.74 0.13 91.04
28 INT234991 Binding of Dsg3 and Positive_regulation of Pik3r1 1 0.05 0.32 0.03 90.32
29 INT234981 Binding of Dsg3 and Negative_regulation of Gsk3b 1 0.07 0.3 0.03 90.32
30 INT234984 Binding of Dsg3 and Positive_regulation of Akt1 1 0.03 0.32 0.03 90.32
31 INT234978 Binding of Dsg3 and Positive_regulation of Inppl1 1 0.00 0.32 0.03 90.32
32 INT234975 Binding of Dsg3 and Negative_regulation of Gsk3a 1 0.03 0.3 0.03 90.32
33 INT232594 CDH1 Regulation of HEPACAM 1 0.01 1.02 0 84.56
34 INT83422 Binding of FANCB and IGHG3 3 0.12 5.09 1.22 81.68
35 INT185997 Binding of FANCB and fc 2 0.01 2.51 0.63 81.68
36 INT225064 Binding of IGHA1 and IGHG3 1 0.01 1.54 0.07 78.76
37 INT234985 Binding of Dsg3 and Pitx3 1 0.00 0.3 0 78.16
38 INT234995 Binding of CDH16 and Jup 1 0.00 0.27 0 76.08
39 INT225082 Binding of IGHG3 and fc 6 0.01 3.6 0.55 74.72
40 INT234990 Binding of Cish and Dsp 1 0.01 0.24 0.04 71.04
41 INT234986 Binding of Rdh2 and Dsp 1 0.00 0.24 0.04 71.04
42 INT235012 Binding of NKS1 and Dsp 1 0.00 0.24 0.04 71.04
43 INT235003 Binding of NKS1 and Rdh2 1 0.00 0.18 0.04 69.80
44 INT234998 Binding of NKS1 and Cish 1 0.00 0.18 0.04 69.80
45 INT235005 Positive_regulation of Binding of DSG1 and Jup 1 0.08 0.36 0 67.20
46 INT192044 Binding of DSP and Jup 2 0.24 2.39 0 66.60
47 INT235018 Binding of DSP and GOPC 1 0.02 0.19 0 65.56
48 INT235007 Binding of DSG1 and Jup 1 0.08 0.36 0 65.52
49 INT234966 Phosphorylation of Jup Regulation of Binding of DSP and Jup 1 0.03 0.49 0 61.52
50 INT135641 Binding of Dst and Ina 1 0.35 0.34 0.06 60.84
51 INT234987 Binding of Jup and Dsp 1 0.01 0.18 0 55.64
52 INT320766 Spp1 Negative_regulation of Dsg1a 1 0.11 1.05 0 50.00
53 INT234982 Binding of Jup and Pkp1 1 0.00 0 0 41.80
54 INT236467 MMP9 Negative_regulation of SNRPB 1 0.01 0.45 0.1 37.40
55 INT232595 Binding of BRCA1 and HEPACAM 1 0.02 0.89 0 35.44
56 INT294894 CYP3A4 Negative_regulation of CYP2C19 1 0.08 0.13 0 19.60
57 INT294895 CYP3A4 Negative_regulation of CYP2C9 1 0.09 0.13 0 19.60
58 INT225067 Binding of ETF1 and IGHG3 1 0.03 4.52 1.17 19.16
59 INT225065 Binding of ETF1 and FANCB 1 0.01 2.07 0.59 19.16
60 INT198700 Binding of DSG3 and Pv 1 0.15 1.45 0.18 14.32
61 INT191816 Binding of ETFA and TGM2 1 0.01 0.66 0 9.60
62 INT206763 Binding of CSF2 and Nqo1 1 0.00 1.7 0.25 8.44
63 INT300890 Binding of Atp9a and Cd79a 1 0.00 0 0 5.36
64 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 5.00
65 INT199593 Binding of TRPV1 and Myoz1 1 0.10 1.7 1.23 5.00
66 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91 5.00
67 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
68 INT113552 Binding of PLAU and PLAUR 4 0.31 3.09 0.72 5.00
69 INT225083 Binding of ETF1 and fc 1 0.00 2.13 0.57 5.00
70 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
71 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44 5.00
72 INT355540 Gnptg Positive_regulation of AMELX 1 0.00 2.16 0.44 5.00
73 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41 5.00
74 INT329800 TLR2 Positive_regulation of Positive_regulation of IL8 1 0.01 0.99 0.41 5.00
75 INT329801 Binding of CAMP and IFNA1 1 0.03 1.48 0.4 5.00
76 INT329799 Binding of CD14 and LY96 2 0.04 1.02 0.39 5.00
77 INT355539 Gnptg Positive_regulation of Mmp23 1 0.00 1.18 0.35 5.00
78 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34 5.00
79 INT300727 IL25 Positive_regulation of IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
80 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
81 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33 5.00
82 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33 5.00
83 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3 5.00
84 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3 5.00
85 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21 5.00
86 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2 5.00
87 INT235014 Car2 Positive_regulation of DSP 1 0.06 0.28 0.2 5.00
88 INT274386 Binding of CD4 and ERVW-1 1 0.05 3.07 0.18 5.00
89 INT329795 IL6 Positive_regulation of Transcription of CCL5 1 0.02 0.59 0.17 5.00
90 INT300753 Binding of Cd28 and Positive_regulation of Transcription of IL13 1 0.00 0 0.17 5.00
91 INT329796 TICAM1 Positive_regulation of IFNA1 2 0.02 0.89 0.15 5.00
92 INT188249 PLAT Positive_regulation of PLG 2 0.10 0.86 0.14 5.00
93 INT300731 IL10 Negative_regulation of Gene_expression of IGHE 1 0.03 0.23 0.13 5.00
94 INT329797 Positive_regulation of TLR2 Positive_regulation of Gene_expression of IL6 1 0.02 1.67 0.11 5.00
95 INT329802 Positive_regulation of TLR2 Regulation of Gene_expression of IL6 1 0.01 1.67 0.11 5.00
96 INT332637 Negative_regulation of Dpp4 Negative_regulation of Localization of Ins1 1 0.06 1.66 0.1 5.00
97 INT329798 Binding of MYD88 and TICAM1 2 0.01 0.24 0.1 5.00
98 INT249117 Binding of Abl1 and Bcr 4 0.36 2.22 0.09 5.00
99 INT230065 Binding of TOR1A and HLA-DOA 1 0.00 1.65 0.09 5.00
100 INT332639 Glp1r Negative_regulation of Localization of Gcg 1 0.03 0.87 0.07 5.00
101 INT225068 Binding of FCAR and IGHG3 1 0.02 0.27 0.07 5.00
102 INT186860 MIR181A2HG Regulation of Cd86 1 0.02 1.05 0.07 5.00
103 INT225081 Binding of FCAR and fc 1 0.00 0.27 0.07 5.00
104 INT186814 MIR181A2HG Regulation of ICAM1 1 0.01 1.05 0.07 5.00
105 INT49112 Binding of SERPINB2 and PLAU 2 0.00 2.06 0.06 5.00
106 INT122480 Binding of SERPINE1 and PLAU 4 0.40 2.75 0.06 5.00
107 INT332641 Binding of PPARG and Ins1 1 0.12 1.05 0.05 5.00
108 INT332631 Negative_regulation of Dpp4 Negative_regulation of Gcg 1 0.05 1 0.05 5.00
109 INT236466 SNRPB Positive_regulation of NFKB2 1 0.00 0.21 0.05 5.00
110 INT332628 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Gcg 1 0.05 1 0.05 5.00
111 INT332638 Gip Regulation of Glp1r 1 0.02 0.47 0.05 5.00
112 INT332633 Glp1r Negative_regulation of Gcg 1 0.04 1.13 0.05 5.00
113 INT332632 Gip Negative_regulation of Localization of Gcg 1 0.05 0.47 0.04 5.00
114 INT241536 Binding of Abcb1b and Abcg2 1 0.10 0.17 0.04 5.00
115 INT332635 Glp1r Regulation of Localization of Gcg 1 0.03 0.94 0.04 5.00
116 INT332640 Glp1r Regulation of Localization of Ins1 1 0.04 0.52 0.04 5.00
117 INT230066 IL15 Positive_regulation of Gene_expression of KLRD1 1 0.01 0.37 0.03 5.00
118 INT274384 AGRP Negative_regulation of HIVEP1 1 0.00 0.77 0.03 5.00
119 INT314771 Glp1r Positive_regulation of Gene_expression of Ins1 2 0.04 1.23 0.03 5.00
120 INT235004 Binding of PKP1 and Dsp 1 0.00 0.14 0 5.00
121 INT337622 SERPINB2 Positive_regulation of Binding of F13A1 and PLAU 1 0.01 0.51 0 5.00
122 INT241588 Binding of FAS and Fas 1 0.05 2.34 0 5.00
123 INT332629 Binding of Glp1r and Positive_regulation of Localization of Gcg 1 0.03 0.47 0 5.00
124 INT337614 F13A1 Positive_regulation of Binding of SERPINB2 and PLAU 1 0.01 0.51 0 5.00
125 INT235011 Ctnnd1 Positive_regulation of RAC1 1 0.00 0.07 0 5.00
126 INT337617 F13A1 Positive_regulation of Binding of PLAU and PLAUR 1 0.01 0.51 0 5.00
127 INT225084 IGHG3 Negative_regulation of fc 1 0.01 0.24 0 5.00
128 INT337616 SERPINE1 Positive_regulation of Binding of PLAU and PLAUR 1 0.03 0.51 0 5.00
129 INT332636 Binding of Glp1r and Positive_regulation of Localization of Ins1 1 0.03 0.47 0 5.00
130 INT337630 Binding of PLAT and PLG 1 0.07 0.69 0 5.00
131 INT234996 Ctnnd1 Positive_regulation of CDC42 1 0.01 0.07 0 5.00
132 INT337621 F13A1 Positive_regulation of Binding of F13A1 and PLAU 1 0.00 0.51 0 5.00
133 INT337615 SERPINB2 Positive_regulation of Binding of SERPINB2 and PLAU 1 0.02 0.51 0 5.00
134 INT337624 SERPINE1 Positive_regulation of Binding of F13A1 and PLAU 1 0.01 0.51 0 5.00
135 INT273136 Binding of CHED1 and VSX1 1 0.15 0.12 0 5.00
136 INT337627 Binding of CLEC3B and Positive_regulation of Positive_regulation of PLG 1 0.52 1.22 0 5.00
137 INT332634 Dpp4 Positive_regulation of Localization of Ins1 1 0.06 0.76 0 5.00
138 INT337620 SERPINB2 Positive_regulation of Binding of SERPINE1 and PLAU 1 0.02 0.51 0 5.00
139 INT337628 Binding of HGF and PLG 1 0.17 0.69 0 5.00
140 INT253212 Negative_regulation of Dpp4 Positive_regulation of Localization of INS 1 0.01 0.42 0 5.00
141 INT337633 Binding of F13A1 and PLAU 1 0.01 0.51 0 5.00
142 INT337623 SERPINE1 Positive_regulation of Binding of SERPINE1 and PLAU 1 0.02 0.51 0 5.00
143 INT234970 Binding of Jup and Lat 1 0.01 0 0 5.00
144 INT337619 F13A1 Positive_regulation of Binding of SERPINE1 and PLAU 1 0.01 0.51 0 5.00
145 INT256400 GLP1R Positive_regulation of Localization of GCG 1 0.02 0.15 0 5.00
146 INT253213 Negative_regulation of Dpp4 Positive_regulation of Localization of GCG 1 0.05 0.4 0 5.00
147 INT235019 Binding of DSC1 and DSP 1 0.39 0.07 0 5.00
148 INT234997 Binding of DSG1 and Car2 1 0.03 0.1 0 5.00
149 INT274385 Binding of ABAT and CDIPT 1 0.00 1.21 0 5.00
150 INT300891 Binding of Atp9a and Tgm2 1 0.00 0.39 0 5.00
151 INT274387 Binding of POLA1 and IGSF9 1 0.01 0.58 0 5.00
152 INT337613 SERPINB2 Positive_regulation of Binding of PLAU and PLAUR 1 0.03 0.51 0 5.00
153 INT337632 PLAU Positive_regulation of PLG 1 0.07 0.36 0 5.00
154 INT337626 Binding of PLAU and CLEC3B 1 0.20 0.4 0 5.00
155 INT332627 Positive_regulation of Ins1 Positive_regulation of Phosphorylation of Hk2 1 0.01 0.83 0 5.00
156 INT236468 TP53 Positive_regulation of Protein_catabolism of SNRPB 1 0.00 0.52 0 5.00
157 INT235015 Binding of DSP and Dsp 1 0.02 0.25 0 5.00
158 INT241535 Abl1 Regulation of Positive_regulation of Jak2 1 0.10 0.53 0 5.00
159 INT337618 SERPINE1 Positive_regulation of Binding of SERPINB2 and PLAU 1 0.02 0.51 0 5.00
160 INT234974 Binding of Lat and Dsp 1 0.00 0 0 5.00
161 INT300892 Binding of Atp8a1 and Tgm2 1 0.01 0.68 0 5.00
162 INT355541 Binding of AMELX and Tnfrsf25 1 0.00 1.36 0 5.00
163 INT225080 Positive_regulation of IGHG3 Negative_regulation of fc 1 0.01 0.24 0 5.00
164 INT241537 Negative_regulation of Binding of Abl1 and Src 1 0.04 0.14 0 5.00
165 INT234993 Binding of Car2 and Dsp 1 0.00 0 0 5.00
166 INT241539 Binding of Abl1 and Lyn 1 0.09 0.14 0 5.00
167 INT355522 Binding of AMELX and HLA-DRB7 1 0.00 1.35 0 5.00
168 INT253214 Negative_regulation of Dpp4 Negative_regulation of Gene_expression of GCG 1 0.04 0.43 0 5.00
169 INT285399 Binding of DEFB1 and HLA-B 1 0.01 1.33 0 5.00
170 INT241534 Binding of Abl1 and Src 1 0.04 0.14 0 5.00
171 INT79163 Binding of PLG and CLEC3B 2 0.29 3.18 0 5.00
172 INT235001 Binding of PKP1 and Sergef 1 0.01 0.06 0 5.00
173 INT235021 PKP1 Regulation of CDC42EP5 1 0.00 0.06 0 5.00
174 INT337631 Binding of HGF and CLEC3B 1 0.42 0.35 0 5.00
175 INT79164 CLEC3B Positive_regulation of Positive_regulation of PLG 2 0.78 2.67 0 5.00
176 INT241538 Negative_regulation of Binding of Abl1 and Lyn 1 0.11 0.14 0 5.00
177 INT337629 Binding of PLAT and CLEC3B 1 0.23 0.35 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Bullous Skin Disease. They are ordered first by their pain relevance and then by number of times they were reported in Bullous Skin Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT234930 Binding of Dsg3 25 0.48 20.73 0.44 100.00
2 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65 100.00
3 INT140647 Gene_expression of DSG1 45 0.75 27.95 1.33 100.00
4 INT195080 Positive_regulation of Tnc 4 0.45 26.67 2.34 100.00
5 INT78190 Gene_expression of Tnc 10 0.75 21.23 2.91 100.00
6 INT27114 Gene_expression of Atp11c 20 0.42 22.22 2.37 100.00
7 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06 100.00
8 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 100.00
9 INT20205 Binding of IgG 108 0.46 66.68 8.57 100.00
10 INT17312 Binding of HSPG2 30 0.41 33.01 4.88 100.00
11 INT240359 Binding of Tnc 2 0.35 11.67 1.48 100.00
12 INT9205 Binding of DSP 12 0.44 9.9 1.21 100.00
13 INT299153 Negative_regulation of Tnc 2 0.42 8.14 0.98 100.00
14 INT75382 Negative_regulation of HSPG2 20 0.57 15.18 7.03 100.00
15 INT53449 Gene_expression of PPL 8 0.75 3.8 1.69 100.00
16 INT71437 Positive_regulation of Gene_expression of Atp11c 2 0.27 5.63 0.16 100.00
17 INT47678 Positive_regulation of Positive_regulation of HSPG2 7 0.49 3.94 3.56 100.00
18 INT76857 Transcription of HSPG2 6 0.60 5.07 0.23 100.00
19 INT178199 Localization of Tnc 2 0.78 5.29 0.16 100.00
20 INT107771 Localization of HSPG2 10 0.78 8.47 4.3 100.00
21 INT43907 Binding of CD79A 28 0.48 28.11 3.04 100.00
22 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 100.00
23 INT40322 Binding of Pnp 12 0.38 11.13 1.78 100.00
24 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 100.00
25 INT320748 Positive_regulation of Protein_catabolism of Dsg1a 1 0.50 1.55 0 100.00
26 INT136791 Negative_regulation of Spp1 24 0.59 23.6 3.33 100.00
27 INT354785 Regulation of Binding of Tnc 1 0.06 1.63 0.53 100.00
28 INT354787 Regulation of Binding of HSPG2 1 0.23 1.63 0.53 100.00
29 INT354784 Positive_regulation of Positive_regulation of Tnc 1 0.07 1.14 0.3 100.00
30 INT44979 Positive_regulation of Pnp 11 0.59 5.61 2.41 100.00
31 INT211097 Negative_regulation of Binding of Pnp 1 0.08 1.27 0.08 100.00
32 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 100.00
33 INT20213 Binding of Atp11c 6 0.08 2.11 0.66 100.00
34 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 100.00
35 INT135640 Negative_regulation of Dst 5 0.57 2.25 1.56 100.00
36 INT135637 Regulation of Dst 3 0.44 1.03 0.2 100.00
37 INT75626 Positive_regulation of Dst 2 0.50 0.52 0.23 100.00
38 INT238521 Positive_regulation of Localization of ATG9A 1 0.34 1.91 0.16 100.00
39 INT234938 Regulation of Negative_regulation of DSG1 1 0.22 1.21 0 99.98
40 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 99.98
41 INT234920 Negative_regulation of Positive_regulation of IgG 3 0.16 2.17 0.04 99.98
42 INT186734 Protein_catabolism of IgG 3 0.26 2.36 0.21 99.98
43 INT201426 Phosphorylation of IgG 2 0.10 0.56 0.04 99.98
44 INT320751 Negative_regulation of Dsg1a 1 0.59 7.3 0.12 99.92
45 INT234915 Positive_regulation of Gene_expression of Jup 1 0.15 2.7 0.06 99.90
46 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 99.90
47 INT88412 Positive_regulation of CDK2 17 0.57 8.49 1.66 99.86
48 INT201460 Positive_regulation of Gene_expression of CDK2 5 0.52 2.8 0.09 99.86
49 INT234857 Gene_expression of Dsg3 42 0.78 27.75 0.14 99.84
50 INT234876 Negative_regulation of Dsg3 29 0.59 25.47 0.4 99.84
51 INT234950 Binding of DSG1 29 0.36 23.67 0.69 99.84
52 INT234908 Negative_regulation of Binding of Dsg3 1 0.31 7.18 0.19 99.84
53 INT234933 Gene_expression of Dsg2 3 0.71 38.52 0.2 99.82
54 INT234954 Negative_regulation of DSG1 22 0.42 19.5 0.62 99.82
55 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61 99.82
56 INT95577 Gene_expression of Afm 2 0.20 1.76 0.97 99.82
57 INT98696 Regulation of Dsg3 4 0.45 5.45 0 99.80
58 INT98697 Regulation of Dsg1a 2 0.45 7.33 0 99.80
59 INT105330 Gene_expression of CDK2 31 0.63 13.7 0.67 99.80
60 INT176528 Regulation of Spp1 9 0.45 9.05 0.77 99.80
61 INT46221 Positive_regulation of Gene_expression of IgG 46 0.53 33.66 7.7 99.76
62 INT320743 Negative_regulation of Gene_expression of Dsg2 1 0.39 3.95 0 99.76
63 INT8775 Binding of IGHE 167 0.48 102.61 23.54 99.76
64 INT234903 Gene_expression of Jup 1 0.23 7.1 0.2 99.74
65 INT234869 Negative_regulation of Binding of Dsg2 1 0.12 5.34 0.11 99.74
66 INT234919 Negative_regulation of Dsg2 5 0.39 6.76 0.04 99.74
67 INT234925 Positive_regulation of Phosphorylation of Hspb2 1 0.11 3.52 0.19 99.74
68 INT234872 Phosphorylation of Hspb2 4 0.24 3.12 0.49 99.74
69 INT320753 Positive_regulation of Localization of Dsg1a 1 0.50 0.76 0 99.72
70 INT17646 Gene_expression of HSPA8 8 0.77 6.75 0.64 99.72
71 INT234918 Positive_regulation of Jup 1 0.15 1.08 0 99.70
72 INT812 Localization of INS 1026 0.81 515.6 145.31 99.70
73 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15 99.68
74 INT313784 Positive_regulation of Negative_regulation of Dsg3 1 0.47 1.3 0 99.68
75 INT73460 Positive_regulation of Gene_expression of Myc 26 0.67 20.44 2.61 99.60
76 INT234951 Negative_regulation of Binding of DSG1 1 0.29 11.2 0.03 99.60
77 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82 99.60
78 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4 99.58
79 INT137960 Positive_regulation of FASLG 8 0.67 6.5 2.34 99.58
80 INT234880 Regulation of Gene_expression of Dsp 1 0.02 4.75 0.03 99.56
81 INT320761 Protein_catabolism of Dsg1a 1 1.00 6.9 0.11 99.54
82 INT234922 Negative_regulation of Dsp 1 0.02 6.01 0.08 99.52
83 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 99.52
84 INT234864 Gene_expression of Dsp 30 0.47 17.72 0.37 99.48
85 INT234888 Binding of Dsg2 9 0.34 11.73 0.11 99.46
86 INT320739 Positive_regulation of Gene_expression of Dsg2 1 0.63 8.03 0 99.46
87 INT234917 Negative_regulation of Gene_expression of Dsg3 1 0.31 3.16 0.09 99.44
88 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 99.44
89 INT313785 Gene_expression of Dsg1a 3 0.78 18.92 0 99.36
90 INT320758 Localization of Dsg1a 1 0.80 4.07 0 99.36
91 INT320750 Regulation of Gene_expression of Dsg1a 1 0.45 3.44 0 99.36
92 INT320749 Regulation of Localization of Dsg1a 1 0.45 2.53 0 99.36
93 INT234894 Negative_regulation of Protein_catabolism of Jup 1 0.17 2.87 0.08 99.32
94 INT234862 Gene_expression of Dsc2 8 0.70 3.29 0 99.24
95 INT234958 Gene_expression of DSC3 1 0.10 2.75 0.11 99.24
96 INT154057 Gene_expression of Ear1 14 0.41 9.72 1.12 99.24
97 INT161779 Positive_regulation of Gene_expression of Ear1 3 0.27 1.91 0.22 99.24
98 INT320763 Regulation of Gene_expression of Dsg2 1 0.41 4.84 0 99.22
99 INT234909 Phosphorylation of Dnajc27 1 0.01 1.47 0.11 99.20
100 INT221860 Negative_regulation of Jup 9 0.15 6.82 0.26 99.18
101 INT234931 Protein_catabolism of Jup 1 0.29 2.23 0.06 99.14
102 INT234860 Protein_catabolism of Dsg3 1 0.52 0.85 0 99.14
103 INT313790 Negative_regulation of Dsc3 1 0.58 3.15 0 99.12
104 INT234949 Phosphorylation of CTNND1 1 0.61 1.9 0.28 99.12
105 INT250396 Localization of GNLY 2 0.68 1.91 0.03 99.12
106 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96 99.08
107 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 99.08
108 INT320740 Positive_regulation of Dsg2 1 0.40 1.09 0 99.08
109 INT96924 Positive_regulation of Hspg2 40 0.49 14.5 12.32 99.04
110 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43 99.00
111 INT235418 Gene_expression of cla 5 0.58 3.27 0.24 99.00
112 INT174195 Negative_regulation of HLA-E 31 0.42 11.98 3.88 99.00
113 INT234898 Negative_regulation of Gene_expression of Dsp 1 0.02 3.92 0.03 98.96
114 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 98.96
115 INT41381 Positive_regulation of Gene_expression of Plg 8 0.44 3.29 1.3 98.96
116 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 98.96
117 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 98.94
118 INT111531 Negative_regulation of Phosphorylation of Mapk14 37 0.50 20 17.68 98.84
119 INT234932 Negative_regulation of Phosphorylation of Hspb2 1 0.09 1.43 0.1 98.84
120 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 98.78
121 INT115999 Regulation of PTPLA 3 0.25 1.83 0.09 98.78
122 INT234939 Positive_regulation of Negative_regulation of DSG1 1 0.23 0.74 0 98.74
123 INT54897 Negative_regulation of HSPA9 3 0.41 5.08 1.19 98.72
124 INT29556 Negative_regulation of CALM1 26 0.57 9.08 6.04 98.68
125 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11 98.68
126 INT115927 Negative_regulation of Hspg2 27 0.57 4.16 4.53 98.68
127 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 98.64
128 INT175216 Negative_regulation of Binding of GOPC 5 0.10 2.05 0 98.64
129 INT320746 Binding of Dsg1a 1 0.48 6.43 0 98.56
130 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 98.54
131 INT176524 Binding of Mapk14 19 0.43 12.54 5.21 98.54
132 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 98.48
133 INT176510 Binding of Spp1 21 0.42 22.1 2 98.46
134 INT105021 Binding of GOPC 187 0.40 60.39 20.38 98.28
135 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 98.24
136 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07 98.24
137 INT313792 Regulation of Hspb2 1 0.08 1.47 0 98.20
138 INT180415 Regulation of Rhoa 7 0.53 3.92 0.22 98.20
139 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 98.16
140 INT70027 Positive_regulation of Gene_expression of C6orf25 10 0.62 7.21 0.83 98.16
141 INT234944 Positive_regulation of Binding of DSG1 1 0.23 0.84 0 98.12
142 INT234868 Regulation of Dsp 1 0.02 0.83 0 98.10
143 INT62692 Localization of Nanog 3 0.73 0.82 1.85 98.08
144 INT17893 Positive_regulation of Myc 4 0.67 3.28 0.06 97.92
145 INT234929 Negative_regulation of Negative_regulation of Dsg3 1 0.31 3.12 0.16 97.88
146 INT320747 Negative_regulation of Binding of Dsg1a 1 0.43 1.36 0 97.84
147 INT234886 Regulation of Dsg2 1 0.09 0.67 0 97.82
148 INT234901 Positive_regulation of Gene_expression of Dsg3 1 0.36 1.94 0 97.80
149 INT90354 Negative_regulation of Myc 6 0.57 4.24 0.4 97.80
150 INT234937 Localization of DSG1 5 0.66 4.14 0 97.80
151 INT24845 Gene_expression of Gnptg 9 0.48 11.42 0.8 97.80
152 INT105960 Gene_expression of Cdh1 41 0.76 22.28 5.56 97.64
153 INT238522 Localization of ATG9A 1 0.54 3.68 0.27 97.58
154 INT92316 Gene_expression of Plaur 30 0.61 22.06 2.21 97.56
155 INT211095 Negative_regulation of Dag1 14 0.57 7.18 1.07 97.56
156 INT229679 Localization of Plec 4 0.65 1.64 0.35 97.52
157 INT229678 Regulation of Localization of Plec 1 0.25 0.78 0.07 97.52
158 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06 97.44
159 INT234907 Protein_catabolism of Dsg2 1 0.13 1.82 0.1 97.40
160 INT140645 Gene_expression of DSG3 6 0.78 4.48 0.52 97.28
161 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 97.24
162 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36 97.24
163 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 97.24
164 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 97.24
165 INT16478 Positive_regulation of Plg 29 0.45 18.07 4.07 97.18
166 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49 97.18
167 INT73263 Negative_regulation of MYC 20 0.57 12.86 2.95 97.08
168 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 96.96
169 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 96.60
170 INT221859 Binding of Jup 2 0.14 2.21 0 96.56
171 INT16389 Gene_expression of Plg 80 0.67 36.88 6.74 96.56
172 INT289704 Protein_catabolism of Spp1 5 0.27 2.42 0.39 96.44
173 INT234893 Positive_regulation of Adam17 4 0.38 3.78 1.22 96.28
174 INT234858 Binding of Cdh1 11 0.47 4.58 0.22 96.24
175 INT106733 Regulation of CDK2 6 0.44 4.76 0.23 96.04
176 INT234952 Protein_catabolism of DSG1 3 0.96 5.86 0.98 95.76
177 INT23105 Gene_expression of MS4A1 5 0.75 5.17 0.95 95.72
178 INT234961 Binding of NKS1 1 0.01 0.5 0.04 95.66
179 INT58930 Negative_regulation of RAC1 14 0.55 7.55 1.4 95.56
180 INT178391 Localization of Mapk14 9 0.68 5.27 0.97 95.44
181 INT234936 Regulation of CCND2 1 0.04 1.15 0 95.28
182 INT60585 Regulation of TP53 59 0.59 54.55 5.21 95.28
183 INT313789 Gene_expression of Dsc3 1 0.76 3 0 95.20
184 INT234905 Positive_regulation of Dsg3 1 0.26 0.73 0.04 95.20
185 INT234887 Positive_regulation of Binding of Dsg3 1 0.26 0.8 0.08 95.20
186 INT173911 Regulation of CD69 3 0.22 2.95 0.25 95.16
187 INT112131 Positive_regulation of Positive_regulation of Egfr 10 0.49 9.95 1.85 95.08
188 INT6481 Binding of TNF 624 0.48 510.2 214.82 95.04
189 INT134952 Localization of DSG3 3 0.81 3.23 0.16 94.80
190 INT327486 Binding of Dpa 1 0.02 1.74 0 94.80
191 INT142384 Gene_expression of XRCC6 3 0.58 1.98 0.16 94.76
192 INT140680 Negative_regulation of DYNLT1 1 0.29 0.93 0.18 94.68
193 INT101889 Negative_regulation of DSP 3 0.42 1.61 1.05 94.64
194 INT250395 Gene_expression of GNLY 5 0.31 1.96 0.07 94.64
195 INT354786 Positive_regulation of Gene_expression of GNLY 1 0.01 1.96 0 94.64
196 INT250402 Positive_regulation of GNLY 2 0.20 1.95 0 94.64
197 INT234945 Negative_regulation of PKP3 1 0.04 1.22 0 94.52
198 INT234881 Negative_regulation of Dsc2 1 0.12 1.21 0 94.52
199 INT234962 Positive_regulation of Gene_expression of DSG1 5 0.48 5.41 0.37 94.52
200 INT188406 Binding of Fasl 19 0.44 24.67 3.17 94.50
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