D:Bursitis

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Disease Term
Synonyms Adhesive Capsulitides, Adhesive Capsulitis, BURSAL SYNOVITIS, BURSITIDES, Capsulitides Adhesive, CAPSULITIS ADHESIVE, Inflammation Of Bursa
Documents 788
Hot Single Events 33
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Bursitis. They are ordered first by their relevance to Bursitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT234113 COL18A1 Negative_regulation of Phosphorylation of VEGFA 1 0.26 0.17 0.16 27.04
2 INT234112 Binding of VEGFA and COL18A1 1 0.21 0.16 0.15 27.04
3 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 5.00
4 INT266742 GOPC Regulation of Positive_regulation of ACR 1 0.02 0.36 1.05 5.00
5 INT351237 HRAS Regulation of CBL 1 0.00 0.48 0.4 5.00
6 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1 5.00
7 INT201973 Bmp7 Positive_regulation of ap 1 0.00 0.18 0.06 5.00
8 INT345350 Casp3 Positive_regulation of Prkcd 1 0.05 0.79 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Bursitis. They are ordered first by their pain relevance and then by number of times they were reported in Bursitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT136310 Negative_regulation of Cxcl12 3 0.37 3.29 0.51 100.00
2 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.88
3 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 99.88
4 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 99.88
5 INT10228 Positive_regulation of PCS 49 0.67 28.72 7 99.82
6 INT122051 Negative_regulation of ROM1 17 0.48 9.11 3.38 99.48
7 INT136309 Positive_regulation of Cxcl12 24 0.62 12.45 5.58 99.36
8 INT165387 Regulation of ROM1 6 0.37 0.87 1.06 98.84
9 INT105199 Regulation of REG3A 1 0.60 0.75 0.06 96.44
10 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 95.92
11 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 94.72
12 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 94.72
13 INT2038 Localization of Esr1 104 0.79 40.12 13.27 94.72
14 INT117080 Localization of Csrp1 6 0.42 7.23 3.09 94.72
15 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17 94.32
16 INT60860 Gene_expression of Slmap 32 0.66 8.55 1.34 91.96
17 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 91.08
18 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 91.08
19 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 91.08
20 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 91.08
21 INT69992 Negative_regulation of Hmox2 93 0.50 49.01 44.07 89.36
22 INT97132 Negative_regulation of Positive_regulation of TBK1 5 0.08 6.54 2.76 88.60
23 INT97145 Positive_regulation of TBK1 14 0.12 15.32 5.43 88.12
24 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 87.56
25 INT82828 Positive_regulation of COMP 45 0.61 35.12 6.2 87.48
26 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 86.32
27 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 85.64
28 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 85.56
29 INT29568 Negative_regulation of Bpifa2 6 0.50 1.83 1.77 85.36
30 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 83.76
31 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 83.68
32 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 82.48
33 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 80.64
34 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 79.80
35 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 79.24
36 INT118095 Regulation of COMP 7 0.43 9.69 3.33 76.80
37 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 75.52
38 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 75.40
39 INT22561 Gene_expression of Arsb 2 0.51 0.72 0.8 75.00
40 INT22562 Localization of Arsb 1 0.60 0.73 0.14 75.00
41 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 73.84
42 INT19188 Binding of Igh-6 11 0.48 2.97 4.88 72.44
43 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 72.24
44 INT48004 Positive_regulation of Negative_regulation of PTGS1 12 0.49 4.07 5.87 72.24
45 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 72.16
46 INT100861 Binding of CRP 179 0.48 175.2 26.45 72.16
47 INT22556 Positive_regulation of Gene_expression of COL3A1 5 0.37 4.25 0.64 70.40
48 INT22558 Gene_expression of COL3A1 10 0.78 7.22 1.36 69.36
49 INT67597 Negative_regulation of Das 17 0.37 9.95 5.05 61.00
50 INT11729 Regulation of IGF1 71 0.61 44.58 9.71 59.60
51 INT38343 Regulation of IGFBP1 8 0.35 3.6 1.75 59.60
52 INT22187 Localization of HTR1D 6 0.78 5.26 5.97 57.64
53 INT107401 Regulation of Das 9 0.18 3.02 1.31 54.56
54 INT3414 Positive_regulation of Negative_regulation of Alb 4 0.44 1.91 1.09 52.60
55 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 51.80
56 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 51.28
57 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 47.44
58 INT27591 Negative_regulation of Gene_expression of Alb 30 0.58 17.03 5.99 47.44
59 INT61645 Negative_regulation of Gc 15 0.51 10.44 2.71 47.44
60 INT152506 Negative_regulation of Gene_expression of Gc 2 0.33 2.29 0.41 47.44
61 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 46.00
62 INT61644 Gene_expression of Gc 16 0.70 11.35 1.95 45.52
63 INT107399 Positive_regulation of Das 7 0.28 1.55 2.74 45.08
64 INT121106 Binding of Slmap 10 0.37 5.19 3.71 45.00
65 INT27534 Negative_regulation of Gba 10 0.57 6.23 0.38 42.00
66 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3 40.80
67 INT83313 Gene_expression of Htr1b 4 0.75 5.1 5.73 38.60
68 INT81982 Gene_expression of Bmpr2 36 0.60 14.58 1.55 38.24
69 INT6594 Gene_expression of HTR1D 60 0.75 10.15 27.13 38.16
70 INT142005 Gene_expression of COL18A1 6 0.75 4.53 0.62 38.04
71 INT94833 Gene_expression of FGF1 4 0.53 2.01 0.81 35.44
72 INT94834 Positive_regulation of Gene_expression of FGF1 2 0.48 1.82 0.56 35.44
73 INT82737 Regulation of Hmox2 7 0.14 4.6 2.44 32.80
74 INT113676 Gene_expression of NRP1 22 0.72 10.81 1.71 31.92
75 INT113675 Regulation of Gene_expression of NRP1 1 0.00 1.62 0 31.92
76 INT183467 Negative_regulation of TBK1 6 0.12 9.89 5.41 29.36
77 INT112183 Gene_expression of CRCP 10 0.67 3.34 7.47 28.40
78 INT4683 Negative_regulation of PDXK 17 0.55 12.81 4.39 27.36
79 INT231466 Binding of COL18A1 2 0.25 1.19 0.18 27.04
80 INT156696 Positive_regulation of Pain1 10 0.23 10.92 12.42 25.00
81 INT97737 Negative_regulation of Phosphorylation of Mapk3 9 0.57 5.64 3.3 24.68
82 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22 24.68
83 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88 24.32
84 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27 23.48
85 INT201968 Positive_regulation of Bmp7 2 0.43 1.11 0.14 21.36
86 INT201967 Positive_regulation of Bmpr2 4 0.31 1.24 0.34 20.80
87 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 18.88
88 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
89 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
90 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
91 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
92 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 5.00
93 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
94 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
95 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 5.00
96 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
97 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
98 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 5.00
99 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
100 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
101 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 5.00
102 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
103 INT117598 Regulation of ACR 118 0.26 41.25 48.01 5.00
104 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 5.00
105 INT5793 Binding of CTS 110 0.48 63.91 40.62 5.00
106 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
107 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
108 INT163134 Gene_expression of ACR 78 0.65 30.39 38.48 5.00
109 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
110 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 5.00
111 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 5.00
112 INT51017 Positive_regulation of Icam1 113 0.70 81.16 35.55 5.00
113 INT132161 Gene_expression of MTX1 48 0.58 26.55 32.32 5.00
114 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 5.00
115 INT5298 Negative_regulation of MTHFS 70 0.57 27.07 28.11 5.00
116 INT3167 Binding of KNG1 48 0.48 23.26 26.77 5.00
117 INT2609 Localization of ELANE 111 0.81 50.22 26.63 5.00
118 INT93360 Gene_expression of Slc6a3 63 0.78 19.54 26.55 5.00
119 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
120 INT48235 Negative_regulation of NPEPPS 72 0.46 44.54 25.03 5.00
121 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
122 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 5.00
123 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09 5.00
124 INT48407 Positive_regulation of Gene_expression of Icam1 61 0.70 57.91 21.54 5.00
125 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78 5.00
126 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
127 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 5.00
128 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
129 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41 5.00
130 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 5.00
131 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 5.00
132 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 5.00
133 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25 5.00
134 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 5.00
135 INT180497 Binding of MRI1 45 0.42 28.35 14.77 5.00
136 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68 5.00
137 INT195226 Positive_regulation of ACR 23 0.26 7.85 12.62 5.00
138 INT37618 Gene_expression of Col2a1 50 0.70 33.88 11.58 5.00
139 INT90639 Positive_regulation of Slc6a3 25 0.61 10.95 10.41 5.00
140 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15 5.00
141 INT82829 Gene_expression of COMP 104 0.78 57 9.81 5.00
142 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
143 INT35269 Localization of SGCG 38 0.78 14.68 9.01 5.00
144 INT173587 Protein_catabolism of COL5A2 59 0.32 32.73 8.96 5.00
145 INT11146 Negative_regulation of CTS 26 0.51 10.33 8.77 5.00
146 INT44775 Gene_expression of ap 33 0.51 6.2 8.65 5.00
147 INT3353 Localization of HLA-B 25 0.75 16.05 8.62 5.00
148 INT90674 Negative_regulation of LOX 56 0.57 38.01 8.58 5.00
149 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 5.00
150 INT61363 Positive_regulation of TFAM 43 0.69 26.43 8.14 5.00
151 INT52937 Gene_expression of Cd68 37 0.67 31.33 7.54 5.00
152 INT21579 Negative_regulation of Gene_expression of TIMP1 25 0.57 12.41 6.94 5.00
153 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 5.00
154 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 5.00
155 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41 5.00
156 INT4863 Positive_regulation of ap 22 0.37 9.13 6.11 5.00
157 INT47976 Protein_catabolism of NFKBIA 17 0.88 7.57 5.79 5.00
158 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78 5.00
159 INT59969 Positive_regulation of Htr1a 12 0.67 5.07 5.73 5.00
160 INT63351 Negative_regulation of Gene_expression of PECAM1 19 0.52 16.06 5.73 5.00
161 INT135319 Positive_regulation of Positive_regulation of CRP 20 0.50 26.45 5.61 5.00
162 INT266746 Binding of ACR 8 0.23 3.44 5.26 5.00
163 INT62525 Positive_regulation of SELE 38 0.70 46 5.25 5.00
164 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9 5.00
165 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 5.00
166 INT17582 Negative_regulation of Localization of ELANE 17 0.53 6.11 4.89 5.00
167 INT9095 Regulation of Gene_expression of COL7A1 24 0.57 10.55 4.88 5.00
168 INT60066 Positive_regulation of NPEPPS 17 0.22 11.99 4.83 5.00
169 INT21582 Regulation of Gene_expression of TIMP1 20 0.61 12.39 4.77 5.00
170 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 5.00
171 INT165058 Negative_regulation of MID1 14 0.37 10.82 4.67 5.00
172 INT5332 Negative_regulation of Gene_expression of NPEPPS 11 0.04 7.79 4.29 5.00
173 INT20981 Binding of HRAS 42 0.48 24.49 4.23 5.00
174 INT125836 Gene_expression of Slc18a2 8 0.72 2.65 4.03 5.00
175 INT80175 Positive_regulation of Gene_expression of HRAS 24 0.67 14.69 3.97 5.00
176 INT169475 Localization of HRAS 14 0.73 9.02 3.9 5.00
177 INT179261 Gene_expression of SERPINA6 12 0.14 3.53 3.82 5.00
178 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69 5.00
179 INT162258 Negative_regulation of Gene_expression of COMP 35 0.58 19.14 3.55 5.00
180 INT106264 Negative_regulation of Gene_expression of Vcam1 13 0.53 10.47 3.55 5.00
181 INT192951 Negative_regulation of AES 15 0.38 6.38 3.5 5.00
182 INT49238 Protein_catabolism of COL1A2 30 0.97 15.64 3.45 5.00
183 INT170606 Regulation of Gene_expression of GOPC 31 0.37 6.08 3.31 5.00
184 INT192450 Gene_expression of CLTC 26 0.55 18.82 3.26 5.00
185 INT22375 Localization of PDGFA 21 0.75 15.46 3.25 5.00
186 INT155039 Gene_expression of ADAMTS5 23 0.67 7.85 3.22 5.00
187 INT279122 Regulation of Gene_expression of COMP 3 0.39 8.82 3.19 5.00
188 INT137262 Positive_regulation of Slc18a2 5 0.68 1.45 3.1 5.00
189 INT92335 Gene_expression of TBK1 11 0.28 8.98 3 5.00
190 INT24821 Binding of VTN 14 0.47 5.83 3 5.00
191 INT200470 Positive_regulation of Gene_expression of COMP 13 0.69 13.73 2.93 5.00
192 INT51460 Negative_regulation of Gene_expression of Sele 8 0.52 10.18 2.89 5.00
193 INT266745 Regulation of Gene_expression of ACR 6 0.10 1.53 2.87 5.00
194 INT74216 Binding of Icam1 16 0.48 10.11 2.69 5.00
195 INT11769 Regulation of Mptp1 8 0.60 6.38 2.68 5.00
196 INT62683 Negative_regulation of HRAS 19 0.57 7.93 2.65 5.00
197 INT151037 Gene_expression of Col10a1 13 0.68 4.47 2.64 5.00
198 INT169987 Transcription of GOPC 45 0.60 21.88 2.61 5.00
199 INT46687 Negative_regulation of Snd1 7 0.38 2.47 2.59 5.00
200 INT15144 Protein_catabolism of IL1B 11 0.92 4.67 2.58 5.00
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