D:Calciphylaxis

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pChart

Disease Term
Synonyms Calciphylaxes
Documents 118
Hot Single Events 36
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Calciphylaxis. They are ordered first by their relevance to Calciphylaxis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87 50.00
2 INT182771 ROS1 Positive_regulation of NFKB1 Positive_regulation of CRP 1 0.00 3.83 0.28 50.00
3 INT182772 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL1B 1 0.00 1.89 0.14 50.00
4 INT182773 ROS1 Positive_regulation of NFKB1 Positive_regulation of IL6 1 0.00 1.9 0.14 50.00
5 INT182780 NFKB1 Positive_regulation of IL1B 1 0.00 1.8 0.14 50.00
6 INT182782 NFKB1 Positive_regulation of IL6 1 0.00 1.8 0.14 50.00
7 INT182775 Binding of PTH and ROS1 1 0.04 1.73 0.04 50.00
8 INT182784 IGF1 Positive_regulation of Gene_expression of INS 1 0.02 1.87 0 50.00
9 INT182804 Binding of ETV3 and T2DM 1 0.10 2.62 0 50.00
10 INT182778 IGF1 Positive_regulation of Gene_expression of ETV3 1 0.03 1.89 0 50.00
11 INT182774 Binding of ETV3 and SAE1 1 0.00 1.17 0 50.00
12 INT182783 INS Positive_regulation of Gene_expression of ETV3 1 0.01 1.89 0 50.00
13 INT182777 IAPP Positive_regulation of Gene_expression of ETV3 1 0.06 1.88 0 50.00
14 INT182776 IAPP Positive_regulation of Gene_expression of INS 1 0.03 1.87 0 50.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Calciphylaxis. They are ordered first by their pain relevance and then by number of times they were reported in Calciphylaxis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT182794 Gene_expression of CPLX1 1 0.06 5.57 0.17 100.00
2 INT182791 Binding of CPLX1 1 0.04 2.85 0.3 100.00
3 INT182799 Positive_regulation of Gene_expression of CPLX1 1 0.04 1.49 0.03 100.00
4 INT182792 Regulation of STS 4 0.47 2.91 0.61 100.00
5 INT182801 Positive_regulation of CPLX1 1 0.04 2.92 0.03 100.00
6 INT182788 Gene_expression of ETV3 8 0.40 11.33 0.36 99.84
7 INT158409 Gene_expression of T2DM 3 0.65 9.58 0.56 99.84
8 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 99.48
9 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 98.96
10 INT82166 Regulation of NOS3 14 0.54 7.57 2.08 98.94
11 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92 98.74
12 INT182753 Positive_regulation of Binding of 1 0.49 1.88 0 98.72
13 INT131019 Binding of T2DM 6 0.47 6.97 0.31 98.72
14 INT182787 Binding of ETV3 14 0.37 25.44 0.37 98.48
15 INT182786 Positive_regulation of Binding of ETV3 1 0.12 1.88 0 98.48
16 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 97.80
17 INT16389 Gene_expression of Plg 80 0.67 36.88 6.74 97.64
18 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 97.00
19 INT1127 Negative_regulation of IGHG3 32 0.28 21.1 7.37 97.00
20 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 97.00
21 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 97.00
22 INT35143 Negative_regulation of ANGPTL5 28 0.54 18.59 3.14 97.00
23 INT62570 Binding of Pth 48 0.48 26.45 4.85 96.40
24 INT59194 Gene_expression of STS 18 0.59 6.74 1.89 96.08
25 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48 95.08
26 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 94.80
27 INT99289 Localization of STS 8 0.79 6.5 0.92 94.00
28 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67 91.92
29 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24 90.12
30 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 89.36
31 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 88.44
32 INT26996 Positive_regulation of Gene_expression of Crp 21 0.68 21.55 2.75 88.44
33 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 88.20
34 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 87.92
35 INT154702 Regulation of Positive_regulation of Pth 1 0.43 0.71 0.09 83.68
36 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 82.92
37 INT19250 Positive_regulation of TAL1 3 0.25 2.51 1.4 78.88
38 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 75.00
39 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04 75.00
40 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 75.00
41 INT57562 Gene_expression of GLA 52 0.77 24.62 6.14 75.00
42 INT3824 Negative_regulation of PTH 40 0.59 28.58 3.39 60.92
43 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 50.00
44 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 50.00
45 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 50.00
46 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 50.00
47 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 50.00
48 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 50.00
49 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 50.00
50 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 50.00
51 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 50.00
52 INT100861 Binding of CRP 179 0.48 175.2 26.45 50.00
53 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 50.00
54 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 50.00
55 INT94784 Binding of ROS1 113 0.40 71.57 10.26 50.00
56 INT16130 Binding of IGF1 67 0.48 27.43 2.95 50.00
57 INT22715 Positive_regulation of Gene_expression of Pth 29 0.64 22.53 2.31 50.00
58 INT12618 Positive_regulation of IAPP 54 0.68 32.03 2.29 50.00
59 INT18844 Binding of IAPP 11 0.36 11.01 1.45 50.00
60 INT6514 Positive_regulation of Gene_expression of PTH 28 0.67 30.28 1.37 50.00
61 INT158540 Negative_regulation of HTN1 4 0.34 7.25 1.22 50.00
62 INT158542 Gene_expression of HTN1 10 0.75 10.69 1.07 50.00
63 INT158541 Positive_regulation of Gene_expression of HTN1 3 0.40 5.88 0.97 50.00
64 INT182790 Positive_regulation of SAE1 3 0.49 3.18 0.39 50.00
65 INT42244 Regulation of Gene_expression of PTH 5 0.45 3.95 0.34 50.00
66 INT182752 Negative_regulation of T2DM 1 0.41 2.06 0.29 50.00
67 INT121834 Gene_expression of IAPP 24 0.66 20.96 0.26 50.00
68 INT6604 Binding of ITGA3 3 0.14 3.37 0.22 50.00
69 INT129762 Binding of HTN1 5 0.03 5.68 0.19 50.00
70 INT182800 Positive_regulation of ETV3 5 0.46 10.01 0.14 50.00
71 INT182785 Gene_expression of NHEJ1 1 0.01 1.08 0.06 50.00
72 INT182754 Positive_regulation of T2DM 1 0.67 4.5 0.03 50.00
73 INT105572 Negative_regulation of TAL1 3 0.23 1.05 0.06 35.96
74 INT16478 Positive_regulation of Plg 29 0.45 18.07 4.07 5.00
75 INT17326 Binding of Plg 14 0.43 11.72 1.94 5.00
76 INT173508 Negative_regulation of Fgfr1 4 0.55 5.08 0.66 5.00
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