D:Capsule Opacification

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Disease Term
Synonyms Capsule Opacifications, Opacification Capsule, Opacifications Capsule
Documents 23
Hot Single Events 67
Hot Interactions 18

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Capsule Opacification. They are ordered first by their relevance to Capsule Opacification and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT347296 PDGFA Positive_regulation of CCL16 1 0.06 0.6 0 99.44
2 INT347304 PDGFA Positive_regulation of Gene_expression of AKT1 1 0.19 0.6 0 99.16
3 INT347295 CCL16 Positive_regulation of Gene_expression of AKT1 1 0.12 0.29 0.03 97.92
4 INT347301 AREG Positive_regulation of CCL16 1 0.01 0.86 0.16 97.24
5 INT285068 ITK Regulation of CCL16 1 0.02 1.86 0.03 96.96
6 INT285071 EGF Positive_regulation of CCL16 1 0.03 0.77 0 96.96
7 INT285074 Positive_regulation of ITK Regulation of CCL16 1 0.04 0.77 0 96.96
8 INT285072 EGF Positive_regulation of ITK 1 0.03 0.77 0 96.36
9 INT285077 CCL16 Positive_regulation of ITK 1 0.05 1.95 0.31 91.92
10 INT347297 ILK Regulation of Gene_expression of AKT1 1 0.21 0.62 0 91.92
11 INT347299 Binding of AKT1 and ITK 1 0.04 0.99 0.04 89.00
12 INT347291 Binding of AKT1 and CCL16 1 0.06 0.99 0.04 89.00
13 INT285070 CCL16 Positive_regulation of Gene_expression of CYP19A1 1 0.02 0.69 0.09 88.96
14 INT347290 Positive_regulation of CCL16 Positive_regulation of PIK3CB 1 0.03 0.57 0 88.00
15 INT347303 Positive_regulation of CCL16 Positive_regulation of AKT1 1 0.08 0.57 0 88.00
16 INT347300 Binding of ITK and CCL16 1 0.02 0.97 0.04 85.48
17 INT285076 CCL16 Positive_regulation of Gene_expression of ITK 1 0.05 1.8 0.14 84.64
18 INT347302 PDGFA Positive_regulation of ITK 1 0.04 1.4 0.09 83.72
19 INT285067 Negative_regulation of ITK Regulation of CCL16 1 0.04 1.1 0.03 79.72
20 INT347292 AREG Negative_regulation of Gene_expression of TERT 1 0.02 0.78 0 79.04
21 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8 75.00
22 INT347298 AREG Negative_regulation of TEP1 1 0.00 0.79 0 72.40
23 INT347294 CCL16 Positive_regulation of Binding of ITK 1 0.02 0.78 0 50.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Capsule Opacification. They are ordered first by their pain relevance and then by number of times they were reported in Capsule Opacification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT109917 Positive_regulation of Gene_expression of CCL16 17 0.66 11.87 2.94 100.00
2 INT269226 Positive_regulation of ITK 13 0.12 11.23 0.4 100.00
3 INT173533 Regulation of Gene_expression of CCL16 5 0.51 3.63 2.63 100.00
4 INT208589 Negative_regulation of Gene_expression of CCL16 3 0.40 2.1 0.52 99.76
5 INT182229 Positive_regulation of CCL16 15 0.66 12.19 8.21 99.68
6 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 99.56
7 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 99.56
8 INT109910 Gene_expression of CCL16 104 0.74 76.1 43.97 99.46
9 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 99.44
10 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5 99.44
11 INT347309 Negative_regulation of Localization of AREG 1 0.03 0.49 0 99.40
12 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 99.38
13 INT347314 Regulation of Gene_expression of ILK 1 0.27 1.15 0 99.28
14 INT98597 Positive_regulation of Gene_expression of ILK 4 0.70 3.08 0.23 99.28
15 INT118792 Regulation of Positive_regulation of AKT1 8 0.61 3.73 1.15 99.12
16 INT98592 Gene_expression of ILK 6 0.78 5.23 0.53 99.02
17 INT173535 Regulation of CCL16 6 0.10 4.93 2.81 99.00
18 INT120717 Positive_regulation of TEP1 50 0.63 27.94 2.81 98.96
19 INT105336 Regulation of AKT1 52 0.56 32.53 4.89 98.92
20 INT108203 Negative_regulation of Gene_expression of AKT1 28 0.54 16.38 3.19 98.76
21 INT285097 Negative_regulation of CCL16 3 0.13 3.88 0.24 98.64
22 INT109470 Negative_regulation of ITK 3 0.24 2.13 0.96 98.64
23 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 98.56
24 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 98.56
25 INT1764 Negative_regulation of Gene_expression of PTGER2 81 0.34 34.74 19.45 98.52
26 INT8096 Positive_regulation of Gene_expression of EGF 21 0.69 13.43 3.47 97.52
27 INT267894 Gene_expression of ITK 13 0.57 9.71 0.9 97.44
28 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 97.16
29 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 96.76
30 INT185896 Gene_expression of AREG 11 0.29 9.45 0.28 96.48
31 INT302231 Localization of AREG 4 0.25 4 0.08 96.48
32 INT86368 Gene_expression of TEP1 31 0.50 16.36 1.63 96.28
33 INT97638 Localization of CCL16 11 0.66 4.89 3.74 96.08
34 INT101866 Positive_regulation of Gene_expression of AKT1 49 0.52 17.47 2.14 95.88
35 INT118791 Binding of AKT1 32 0.48 15.51 2.25 95.72
36 INT173537 Binding of CCL16 18 0.40 13.02 7.36 95.24
37 INT273474 Positive_regulation of Gene_expression of Lefty1 1 0.01 1.61 0.26 94.00
38 INT269220 Positive_regulation of Gene_expression of ITK 4 0.14 3.07 0.41 93.56
39 INT135556 Localization of AKT1 38 0.69 12.78 1.17 93.00
40 INT172959 Gene_expression of Lefty1 4 0.21 5.15 0.76 92.88
41 INT76892 Gene_expression of FGFR1 45 0.69 23.6 7.56 92.88
42 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 92.88
43 INT108585 Positive_regulation of Gene_expression of CASP3 35 0.70 28.37 6.45 92.52
44 INT347315 Binding of PIK3CB 2 0.19 1.57 0 92.20
45 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2 92.12
46 INT77925 Negative_regulation of TEP1 21 0.53 15.23 2.62 91.92
47 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 91.20
48 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 89.04
49 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57 89.04
50 INT285095 Regulation of GSPT1 1 0.00 0.83 0.03 89.04
51 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 88.96
52 INT89392 Negative_regulation of Positive_regulation of AKT1 23 0.50 15.69 3.02 88.00
53 INT340980 Negative_regulation of Positive_regulation of PIK3CB 2 0.12 0.59 0 88.00
54 INT178118 Positive_regulation of PIK3CB 12 0.32 5.06 0.19 88.00
55 INT171040 Transcription of CCL16 11 0.68 7.09 3.86 87.64
56 INT285096 Transcription of ITK 1 0.17 0.77 0.1 87.32
57 INT178607 Binding of CASP3 5 0.19 1.06 0.16 87.28
58 INT101572 Negative_regulation of Gene_expression of PCNA 24 0.53 13.87 2.21 86.88
59 INT117343 Negative_regulation of AREG 2 0.03 1.37 0.18 86.68
60 INT347310 Phosphorylation of CCL16 1 0.18 0.7 0.04 86.40
61 INT59080 Negative_regulation of Gene_expression of PTGS2 55 0.58 22.92 12.39 86.08
62 INT1763 Regulation of Gene_expression of PTGER2 43 0.36 23.98 10.95 85.80
63 INT347305 Negative_regulation of Positive_regulation of PDGFA 1 0.17 0.56 0 84.72
64 INT347311 Negative_regulation of Positive_regulation of CCL16 1 0.09 0.56 0 84.72
65 INT9020 Binding of Tsv 2 0.25 1.28 0.48 84.08
66 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34 83.64
67 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5 82.32
68 INT121496 Gene_expression of TERT 107 0.78 45.6 7.42 79.04
69 INT285094 Binding of ITK 4 0.11 2.14 0.05 78.36
70 INT8765 Positive_regulation of Cyp3a23/3a1 63 0.67 22.28 20.39 75.00
71 INT67719 Positive_regulation of Col1a1 21 0.44 8.87 3.12 75.00
72 INT135780 Gene_expression of Pax6 12 0.76 3.17 1.06 75.00
73 INT135779 Negative_regulation of Gene_expression of Pax6 2 0.57 0.79 0.8 75.00
74 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37 73.48
75 INT167409 Regulation of Gene_expression of AKT1 8 0.56 4.86 1.23 72.80
76 INT302248 Negative_regulation of Binding of AKT1 2 0.25 1 0.14 69.52
77 INT347316 Negative_regulation of Binding of TERT 1 0.18 0.26 0 68.80
78 INT147607 Binding of TERT 16 0.48 12.36 1.31 68.80
79 INT347318 Positive_regulation of Binding of CCL16 1 0.11 0.76 0 67.04
80 INT347313 Binding of ILK 1 0.22 0.12 0 62.40
81 INT347307 Regulation of Binding of ILK 1 0.27 0.12 0 62.40
82 INT297602 Positive_regulation of Tsv 3 0.07 3.36 0.33 61.52
83 INT299871 Regulation of Foxe3 1 0.44 0.23 0 57.68
84 INT229940 Positive_regulation of amd 10 0.49 27.97 0.15 57.48
85 INT299855 Gene_expression of Foxe3 1 0.75 0.21 0 54.08
86 INT39513 Positive_regulation of TRAP 14 0.48 5.11 1.67 50.00
87 INT189736 Regulation of TERT 22 0.40 3.58 1.29 50.00
88 INT102845 Localization of CASP3 7 0.81 2.81 1.06 50.00
89 INT117344 Binding of AREG 4 0.11 2.14 0.34 50.00
90 INT139391 Regulation of PCNA 10 0.60 3.12 0.33 50.00
91 INT176153 Regulation of Negative_regulation of AKT1 3 0.39 2.13 0.16 50.00
92 INT189767 Positive_regulation of Gene_expression of TEP1 4 0.30 1.43 0.11 50.00
93 INT324526 Positive_regulation of Gene_expression of AREG 4 0.24 2.31 0.03 50.00
94 INT347317 Localization of ILK 1 0.45 0 0 50.00
95 INT347308 Positive_regulation of Binding of AREG 1 0.04 0.05 0 50.00
96 INT347306 Regulation of Negative_regulation of CCL16 1 0.10 0.11 0 50.00
97 INT274377 Localization of TERT 3 0.70 0.78 0 50.00
98 INT299860 Localization of Prox1 1 0.79 0 0 31.36
99 INT299861 Positive_regulation of Prox1 1 0.68 0 0 23.28
100 INT311459 Negative_regulation of Cle 1 0.20 0.3 0 17.44
101 INT88726 Gene_expression of HPRT1 36 0.78 10.12 1.58 9.28
102 INT58489 Gene_expression of Rorb 51 0.41 4.7 5.39 5.00
103 INT58488 Positive_regulation of Gene_expression of Rorb 7 0.19 1.98 1.63 5.00
104 INT60766 Gene_expression of COL4A4 10 0.77 13.46 1.14 5.00
105 INT19716 Gene_expression of Ecd 9 0.41 2.18 0.57 5.00
106 INT231517 Gene_expression of EFNA5 1 0.65 0.09 0.29 5.00
107 INT142338 Gene_expression of Noto 2 0.25 0.57 0.21 5.00
108 INT164966 Binding of Cle 2 0.32 0.91 0.19 5.00
109 INT231267 Localization of Ecd 3 0.18 0.84 0.12 5.00
110 INT299853 Gene_expression of Crybb2 4 0.68 2.05 0.11 5.00
111 INT164965 Gene_expression of Cle 4 0.58 3.73 0.1 5.00
112 INT299869 Positive_regulation of Gene_expression of Crybb2 2 0.44 0.69 0.08 5.00
113 INT299874 Regulation of Gene_expression of Crybb2 3 0.39 1.27 0.07 5.00
114 INT299864 Transcription of Prox1 4 0.52 1.13 0.06 5.00
115 INT299866 Gene_expression of Prox1 12 0.76 1.12 0.06 5.00
116 INT346651 Gene_expression of Tsv 1 0.10 0.59 0.06 5.00
117 INT311458 Positive_regulation of Gene_expression of Cle 1 0.23 0.83 0.04 5.00
118 INT299873 Binding of Foxe3 1 0.36 0 0 5.00
119 INT299858 Positive_regulation of Transcription of Prox1 1 0.46 0 0 5.00
120 INT299859 Transcription of Pax6 1 0.70 0 0 5.00
121 INT299872 Positive_regulation of Gene_expression of Prox1 1 0.46 0 0 5.00
122 INT299868 Transcription of Crybb2 1 0.47 0 0 5.00
123 INT138963 Positive_regulation of Noto 2 0.01 0 0 5.00
124 INT299857 Regulation of Pax6 1 0.60 0 0 5.00
125 INT299863 Binding of Prox1 1 0.36 0 0 5.00
126 INT299870 Positive_regulation of Localization of Prox1 1 0.49 0 0 5.00
127 INT299856 Negative_regulation of Gene_expression of Prox1 1 0.42 0 0 5.00
128 INT311457 Positive_regulation of Cle 1 0.22 1.22 0 5.00
129 INT299876 Transcription of Cryba2 1 0.45 0 0 5.00
130 INT299865 Transcription of Crygd 1 0.42 0 0 5.00
131 INT299875 Transcription of Cryab 1 0.43 0 0 5.00
132 INT299867 Transcription of Crybb1 1 0.46 0 0 5.00
133 INT299854 Binding of Pax6 1 0.36 0 0 5.00
134 INT299862 Transcription of Cryaa 1 0.46 0 0 5.00
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