D:Cardiovascular Disease

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Disease Term
Synonyms CARDIOVASCULAR DISEASES, Cardiovascular Disorder, CARDIOVASCULAR DYSFUNCTION, CARDIOVASCULAR SYNDROME, CARDIOVASCULAR THROMBOSIS, CORONARY ARTERY DISEASE, Cvd, DISEASE AFFECTING ENTIRE CARDIOVASCULAR SYSTEM, Disease Cardiovascular, Disease Of Cardiovascular System, DISEASE SYNDROME OF CARDIOVASCULAR SYSTEM
Documents 5989
Hot Single Events 200
Hot Interactions 160

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cardiovascular Disease. They are ordered first by their relevance to Cardiovascular Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT263100 Binding of EFS and COPD 1 0.14 4.14 0.07 100.00
2 INT250015 Binding of FLNA and Nos3 1 0.05 1.09 0.06 100.00
3 INT302596 Eef1a2 Negative_regulation of LDLR 1 0.14 0.31 0 100.00
4 INT242037 Binding of CRP and SNRNP70 3 0.07 4.62 0.19 100.00
5 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03 99.92
6 INT291643 Binding of DST and INS 1 0.07 0.38 0 99.92
7 INT260563 Hdl1 Positive_regulation of Positive_regulation of Nos3 1 0.05 1.55 0 99.90
8 INT288910 REN Regulation of Gene_expression of AGT 1 0.40 1.34 0 99.88
9 INT250550 Binding of F12 and CHDH 1 0.05 2.26 0.17 99.84
10 INT250557 Binding of PITX2 and CHDH 1 0.00 2.83 0 99.80
11 INT250551 Binding of USF1 and CHDH 1 0.04 0.7 0 99.80
12 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36 99.76
13 INT300197 Binding of APOA1 and C1S 1 0.39 3.56 0 99.76
14 INT335606 Binding of CISH and LAP 1 0.14 2.21 0 99.72
15 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02 99.48
16 INT238895 Binding of CRP and INS 1 0.00 0.93 0.32 99.36
17 INT300641 Binding of APOE and CRP 1 0.41 0.81 0.07 99.30
18 INT113780 AGT Positive_regulation of Positive_regulation of Nfkb1 1 0.00 1.25 0.64 99.12
19 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68 99.04
20 INT161251 Ptgs2 Regulation of Mapk14 1 0.16 0.82 0.54 98.96
21 INT168941 Irs2 Regulation of Gene_expression of Igf1r 1 0.39 0.91 0.16 98.88
22 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12 98.60
23 INT320600 TNS3 Regulation of CEBPZ 1 0.29 1.96 0.74 98.54
24 INT150533 Positive_regulation of LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12 98.48
25 INT150532 LEP Negative_regulation of Adipoq 1 0.00 1.34 0.12 98.48
26 INT323773 Binding of Il6 and Lep 1 0.29 3.54 0.6 98.44
27 INT277010 Binding of PAPPA and TNNT1 1 0.24 0.99 0.07 98.32
28 INT277016 Binding of MB and PAPPA 1 0.10 1 0.07 98.32
29 INT161250 Trib3 Regulation of Mapk14 1 0.04 0.81 0.54 98.12
30 INT326057 APOA1 Regulation of Localization of APOE 1 0.54 1.36 0 97.92
31 INT201485 Ntrk2 Positive_regulation of Prkcg 1 0.01 0.73 0.38 97.84
32 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04 97.76
33 INT171162 Negative_regulation of Ace Negative_regulation of Gene_expression of Ccl2 1 0.02 1.18 0.1 97.76
34 INT213175 Binding of DBP and HP 1 0.03 1.08 0 97.74
35 INT213176 Binding of HP and SHBG 1 0.02 1.07 0 97.74
36 INT300196 Binding of HSD11B1 and CHDH 1 0.07 4.01 0 97.72
37 INT300195 Binding of C1S and CHDH 1 0.23 2.51 0 97.56
38 INT351984 Gene_expression of Stk11 Positive_regulation of Gene_expression of Dcc 1 0.01 1.8 0 97.52
39 INT351985 Stk11 Positive_regulation of Gene_expression of Dcc 1 0.01 1.79 0 97.52
40 INT323279 Binding of Nos3 and Arg2 1 0.01 0.67 0 97.44
41 INT139565 Negative_regulation of Binding of PLEK and Tbxa2r 1 0.01 0.57 0.19 97.40
42 INT192356 Binding of CP and CRP 1 0.16 4.35 0 97.24
43 INT309001 Ins1 Positive_regulation of Mmp9 1 0.20 1.96 0.83 97.20
44 INT329589 Serpina5 Positive_regulation of PTX3 1 0.03 1.52 0.66 97.04
45 INT229371 Positive_regulation of Pparg Negative_regulation of Gene_expression of Edn1 1 0.01 0.92 0.04 97.04
46 INT139566 Binding of PLEK and Tbxa2r 1 0.01 1.14 0.38 96.84
47 INT120896 Binding of CCL2 and Il6 1 0.08 1.2 0.26 96.80
48 INT308643 Binding of Proc and Renbp 1 0.00 1.61 0 96.76
49 INT170590 RELA Negative_regulation of Gene_expression of ICAM1 1 0.42 0.49 0 96.72
50 INT230857 Negative_regulation of Binding of HSP90AA1 and NOS1 1 0.05 1.18 0.09 96.20
51 INT350823 Binding of SAA1 and SELS 1 0.17 2.75 0.05 96.12
52 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 96.04
53 INT307698 Binding of Crp and pad 1 0.04 3.71 0.12 95.88
54 INT284095 HNF1A Positive_regulation of TIMP3 1 0.38 2.3 0 95.88
55 INT284098 HNF1A Positive_regulation of SLC2A1 1 0.36 1.16 0 95.88
56 INT284092 HNF1A Positive_regulation of FGD2 1 0.15 1.16 0 95.88
57 INT351976 Binding of Tp53 and Stk11 1 0.13 2.3 0 95.76
58 INT192309 Binding of GSTM1 and GSTT1 2 0.43 4.54 0.06 95.72
59 INT230856 Binding of HSP90AA1 and NOS1 1 0.04 1.17 0.09 95.56
60 INT213023 Hdl1 Regulation of Nos3 2 0.09 4.06 0.09 95.48
61 INT285241 Binding of Crp and Il6 1 0.00 1.78 0.27 95.00
62 INT351977 Binding of Tp53 and Trib3 1 0.01 0.79 0 94.76
63 INT98066 Binding of Plau and Plau 1 0.00 1.49 0.34 94.64
64 INT216881 Binding of Apoc4 and Hmox1 1 0.01 1.78 0.4 94.64
65 INT179689 Binding of CYP4F3 and DAK 1 0.00 1.23 0.2 94.08
66 INT178334 Binding of Pon1 and Chdh 1 0.11 11.45 0.66 93.76
67 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43 93.20
68 INT330530 Binding of PON1 and CIMT 1 0.14 1.48 0 92.92
69 INT260397 Positive_regulation of Hmox1 Positive_regulation of Gene_expression of Adipoq 1 0.37 0.78 0.22 92.88
70 INT329847 PPARA Regulation of Gene_expression of CREB3L3 1 0.17 0.84 0.13 92.72
71 INT250016 Binding of IGHE and Il13 1 0.01 4.59 0.97 92.48
72 INT118344 Binding of Crp and F7 1 0.01 0.19 0 92.36
73 INT260394 Positive_regulation of Hmox1 Positive_regulation of Adipoq 1 0.37 0.78 0.19 92.32
74 INT240620 Binding of INS and SHBG 4 0.12 3.35 0.15 92.16
75 INT286433 Negative_regulation of Binding of Shbg and ANTXR2 1 0.06 1.29 0 92.00
76 INT286434 Binding of Shbg and ANTXR2 1 0.05 1.29 0 92.00
77 INT245216 Binding of C3 and C3AR1 1 0.19 1.21 0.04 92.00
78 INT332285 Binding of KLRD1 and CRLF1 1 0.00 1.71 0.14 91.88
79 INT333991 Binding of FLNA and SELL 1 0.00 1.69 0.55 91.84
80 INT257879 Negative_regulation of Eif4e Positive_regulation of Cdkn1b 1 0.28 0.54 0.06 91.76
81 INT257867 Negative_regulation of Eif4e Positive_regulation of Rb1 1 0.05 0.54 0.06 91.76
82 INT245219 Binding of C3AR1 and C5AR1 1 0.34 1.21 0.04 91.60
83 INT245218 Binding of C3 and C5AR1 2 0.29 2.94 0.04 91.60
84 INT332970 Binding of Ppara and Tmed4 1 0.05 1.91 0.03 91.56
85 INT260600 Binding of Ppargc1a and Siglec1 1 0.14 1.25 0 90.88
86 INT265934 SREBF1 Positive_regulation of Transcription of SERPINE1 1 0.01 0.62 0 90.56
87 INT240129 Binding of Nppb and Crp 1 0.21 1.02 0.32 90.48
88 INT306922 Negative_regulation of Ephx2 Positive_regulation of Hdl1 1 0.05 1.06 0 90.12
89 INT111664 Binding of CPN1 and Alb 1 0.00 0.98 0.24 89.92
90 INT242203 GLP1R Regulation of GCG 1 0.04 0.64 0.1 89.88
91 INT250553 Binding of RS1 and SUGT1 3 0.00 3.36 0.22 89.80
92 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65 89.76
93 INT270759 Binding of HSD11B1 and TERT 1 0.07 1.67 0 89.72
94 INT308648 Binding of sps and Gopc 1 0.01 2.71 0 89.68
95 INT342910 LPA Negative_regulation of PLG 1 0.15 0.44 0 89.52
96 INT342457 CSF1 Negative_regulation of Gene_expression of CCR4 1 0.00 0.93 0.31 89.28
97 INT342458 CSF1 Positive_regulation of Gene_expression of CCL2 1 0.17 0.84 0.27 89.28
98 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78 89.20
99 INT348322 Il6 Positive_regulation of Localization of Crp 1 0.06 3.51 0.51 88.76
100 INT333993 Binding of Vcam1 and Vwf 1 0.00 1.32 0.33 88.64
101 INT284090 VWF Negative_regulation of SERPINA1 1 0.04 2.34 0 88.56
102 INT350835 Binding of SELS and Sels 1 0.16 1.24 0.26 88.12
103 INT250554 Binding of F5 and SELS 1 0.24 1.07 0 88.08
104 INT192355 Binding of CP and FCGR3A 1 0.01 1.22 0 87.72
105 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 87.04
106 INT284091 VWF Negative_regulation of PON2 1 0.41 2.32 0 86.96
107 INT284093 VWF Negative_regulation of APOE 1 0.40 2.32 0 86.96
108 INT284094 VWF Negative_regulation of CNDP2 1 0.14 1.16 0 86.96
109 INT73794 Binding of HSD11B1 and Igfbp1 1 0.06 1.15 0.07 86.96
110 INT260565 T2dm2 Regulation of SUGT1 1 0.00 1.43 0.05 86.72
111 INT251469 INS Negative_regulation of Gene_expression of SHBG 2 0.11 4.11 0.08 86.72
112 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 86.48
113 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69 86.48
114 INT334393 IL6 Positive_regulation of Tnf 1 0.16 1.41 0.35 86.12
115 INT306794 Binding of LEP and COPD 1 0.15 3.94 0.09 86.12
116 INT302384 IL6 Positive_regulation of Localization of Crp 1 0.10 1.39 0.15 86.04
117 INT216880 Apoc4 Positive_regulation of Hmox1 1 0.03 1.06 0.25 85.52
118 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 85.40
119 INT285243 EGF Positive_regulation of Egf 1 0.00 1.55 0.27 85.28
120 INT285238 EGF Positive_regulation of VEGFA 1 0.01 1.55 0.27 85.28
121 INT126551 Agt Positive_regulation of Gene_expression of Ptgs1 1 0.25 0.92 0.24 85.16
122 INT126552 Agt Positive_regulation of Gene_expression of Ptgs2 1 0.32 0.92 0.24 85.16
123 INT126549 Agt Positive_regulation of Ptgs2 1 0.32 0.9 0.23 85.16
124 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09 84.68
125 INT286650 Binding of IGHG3 and OLR1 1 0.01 0.42 0 84.68
126 INT353865 Binding of CHI3L1 and Lepr 1 0.00 1.88 0.03 84.48
127 INT257869 Rps6kb1 Regulation of Eif4ebp1 1 0.02 0.64 0.04 84.00
128 INT257872 Eif4ebp1 Regulation of Rps6kb1 1 0.02 0.64 0.04 84.00
129 INT253945 Adrm1 Negative_regulation of Hdl1 1 0.00 1.18 0 83.92
130 INT220155 IL1RN Regulation of IL1B 2 0.50 0.93 0.61 83.88
131 INT286653 Binding of CD40LG and OLR1 1 0.08 0.41 0 83.80
132 INT155388 Binding of LPA and Lipg 1 0.00 1.22 0.12 83.72
133 INT155387 Binding of LPA and RT1-A 1 0.00 1.22 0.12 83.72
134 INT298476 CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12 83.68
135 INT298479 CD40LG Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.00 0.33 0.12 83.68
136 INT298474 IL4 Positive_regulation of HLA-DRB1 1 0.02 0.33 0.12 83.68
137 INT298478 IL4 Positive_regulation of CD40LG Positive_regulation of HLA-DRB1 1 0.01 0.33 0.12 83.68
138 INT267684 Binding of INS and ARID1B 3 0.10 6.08 0.09 83.52
139 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11 83.12
140 INT284096 Binding of MAP4 and VWF 1 0.35 0.82 0.04 83.00
141 INT284097 Binding of MAP4 and WNK1 1 0.39 0.82 0.04 83.00
142 INT229007 MIA3 Positive_regulation of Gene_expression of Ccnd1 1 0.01 0.55 0 82.96
143 INT250555 Binding of APOBEC2 and CHDH 1 0.04 0.57 0 82.92
144 INT224040 Mtpn Positive_regulation of P2RY1 1 0.00 0.85 0.12 82.80
145 INT298471 CD40LG Positive_regulation of CD80 1 0.04 0.33 0.12 82.80
146 INT298473 IL4 Positive_regulation of CD80 1 0.06 0.33 0.12 82.80
147 INT342581 Binding of Dbp and Pth 1 0.04 2.12 0.04 82.48
148 INT187290 Binding of HEY1 and Gtf3a 1 0.00 6.18 0.83 82.48
149 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 0.30 2.33 0.83 81.24
150 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1 81.20
151 INT308653 Proc Regulation of Gene_expression of Mapk8 1 0.00 1.48 0.36 80.88
152 INT164263 TGM7 Negative_regulation of CCND3 1 0.04 1.08 0.54 80.56
153 INT164265 TGM7 Negative_regulation of CDK2 1 0.26 1.08 0.53 80.56
154 INT164264 TGM7 Negative_regulation of CCNB1 1 0.07 1.08 0.53 80.56
155 INT164262 TGM7 Negative_regulation of E2F1 1 0.16 1.08 0.53 80.56
156 INT230853 Binding of SELE and VWF 1 0.06 1.3 0.07 80.52
157 INT179492 Binding of Ins1 and Adipoq 1 0.16 1.16 0.23 80.32
158 INT313554 Binding of ALOX5 and Cor 1 0.02 2.47 0.17 80.28
159 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09 80.24
160 INT242204 DPP4 Positive_regulation of Gene_expression of GLP1R 1 0.03 0.66 0.1 80.04
161 INT257877 Ins1 Positive_regulation of Phosphorylation of Ntrk2 1 0.00 0.66 0.04 80.00
162 INT232576 ROS1 Positive_regulation of Localization of OLR1 1 0.04 0.7 0 80.00
163 INT224531 Positive_regulation of Map2k1 Positive_regulation of Positive_regulation of Ankh 1 0.07 0.54 0.09 79.80
164 INT323675 Binding of THBD and BDNF-AS 1 0.02 2.45 0.04 79.76
165 INT323674 Binding of TFPI and THBD 1 0.02 2.45 0.04 79.76
166 INT207576 RETN Positive_regulation of Gene_expression of EDN1 1 0.05 0.78 0.33 79.76
167 INT351974 Agt Positive_regulation of Gene_expression of Stk11 1 0.51 11.1 0.12 79.64
168 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 79.48
169 INT305270 Lep Negative_regulation of Localization of Car2 1 0.16 1.28 0 79.08
170 INT313498 Binding of ALOX5 and SNRNP70 1 0.05 2.7 0.21 79.04
171 INT230816 Binding of ras and Ren1 1 0.11 0.77 0.04 79.04
172 INT192354 Binding of CRP and HSPD1 1 0.12 1.28 0 79.00
173 INT213030 Hdl1 Regulation of Gene_expression of Edn1 1 0.06 0.88 0 78.64
174 INT257878 Ins1 Positive_regulation of Gene_expression of Ntrk2 1 0.00 0.65 0.04 78.40
175 INT344396 Ucp2 Regulation of Ros1 1 0.04 1.31 0.31 78.20
176 INT175596 Binding of ACAT1 and HGF 1 0.01 1.58 0.18 78.16
177 INT170817 CMA1 Positive_regulation of Gene_expression of AGT 1 0.19 1.41 0.14 77.96
178 INT277012 Binding of PAPPA and ACE2 1 0.02 1.26 0.15 77.76
179 INT173199 CNOT4 Regulation of Regulation of Myc 1 0.01 0.66 0.03 77.76
180 INT291642 Binding of DST and GGT1 1 0.00 1.4 0.19 77.60
181 INT313503 Binding of ALOX5AP and CXADRP1 1 0.01 1.51 0.08 77.48
182 INT313551 Binding of ALOX5AP and Cor 1 0.02 1.01 0.03 77.48
183 INT101318 Negative_regulation of Binding of tf and Selp 1 0.01 0.77 0.17 77.40
184 INT101316 Binding of tf and Selp 1 0.01 0.77 0.17 77.40
185 INT244481 Binding of ERN1 and ATF6 1 0.17 0.69 0 77.36
186 INT244465 Binding of EIF2AK3 and ATF6 1 0.14 0.69 0 77.36
187 INT284088 Binding of BDNF and NTRK2 5 0.41 3.4 2.37 77.28
188 INT250556 Binding of FGA and HSD11B1 1 0.33 0.57 0 77.28
189 INT250552 Binding of FGG and HSD11B1 1 0.25 0.57 0 77.28
190 INT355103 Binding of Ins2 and Ins1 1 0.12 2 0.21 77.24
191 INT210899 Binding of SELE and IGHD1-14 1 0.39 3.31 0.11 77.20
192 INT210897 Binding of SNRNP70 and IGHD1-14 1 0.01 1.63 0.08 77.20
193 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 77.12
194 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6 77.08
195 INT257873 Ins1 Positive_regulation of Pik3cg 1 0.13 1.05 0.11 77.08
196 INT150048 Ins1 Positive_regulation of Rps6kb1 2 0.23 0.83 0.04 77.08
197 INT257881 Ins1 Positive_regulation of Mtor 1 0.05 0.37 0.04 77.08
198 INT140813 Binding of Retn and Adipoq 1 0.03 1.18 0.06 77.00
199 INT224026 P2RY6 Positive_regulation of NRP2 1 0.10 0.98 0.1 76.88
200 INT225556 Binding of Ncoa6 and Cytip 1 0.12 1.7 0.04 76.72

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cardiovascular Disease. They are ordered first by their pain relevance and then by number of times they were reported in Cardiovascular Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT2774 Binding of Crp 241 0.48 195.89 44.39 100.00
2 INT17086 Binding of HSD11B1 84 0.47 122.28 6.16 100.00
3 INT22454 Regulation of Crp 213 0.62 160.67 49.24 100.00
4 INT100861 Binding of CRP 179 0.48 175.2 26.45 100.00
5 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 100.00
6 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55 100.00
7 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 100.00
8 INT23257 Regulation of CRP 127 0.62 100.05 21.87 100.00
9 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 100.00
10 INT36064 Binding of CST3 14 0.47 16.38 1.12 100.00
11 INT56447 Positive_regulation of Icam1 64 0.64 64.14 16.16 100.00
12 INT39948 Binding of FLNA 45 0.42 58.05 4.27 100.00
13 INT84979 Regulation of CHDH 22 0.38 22.34 0.78 100.00
14 INT106745 Localization of CRP 65 0.81 66.44 15.21 100.00
15 INT99550 Regulation of FLNA 51 0.54 27.88 2.58 100.00
16 INT28020 Binding of Adipoq 10 0.36 11.49 0.77 100.00
17 INT12082 Localization of IL6 365 0.81 241.78 105.78 100.00
18 INT15449 Positive_regulation of Plat 32 0.69 12.76 9.71 100.00
19 INT32314 Positive_regulation of Positive_regulation of Pf4 2 0.49 2.65 0.71 100.00
20 INT31582 Gene_expression of Hdl1 103 0.66 118.95 6.42 100.00
21 INT60109 Positive_regulation of Positive_regulation of Plat 1 0.02 1.91 0.04 100.00
22 INT20238 Regulation of APOB 9 0.61 11.52 1.26 100.00
23 INT23191 Gene_expression of HDLCQ1 13 0.60 14.39 1.58 100.00
24 INT6852 Localization of TNF 883 0.81 705.95 270.84 100.00
25 INT46646 Localization of FLNA 19 0.73 18.83 2.53 100.00
26 INT43985 Regulation of LPA 29 0.62 20.79 3.29 100.00
27 INT17996 Binding of Crp 40 0.37 31.4 7.8 100.00
28 INT47780 Gene_expression of CREM 17 0.74 5.37 2.13 100.00
29 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81 100.00
30 INT157467 Positive_regulation of Gene_expression of CX3CL1 6 0.55 16.67 8.84 100.00
31 INT119729 Binding of Tnfsf11 31 0.35 24.02 7.45 100.00
32 INT72936 Gene_expression of Pparg 39 0.77 19.01 4.02 100.00
33 INT45159 Regulation of Nppb 16 0.54 13.57 4.46 100.00
34 INT183080 Gene_expression of Hypt 5 0.14 7.53 0.85 100.00
35 INT121335 Localization of SCD 10 0.68 6.81 1.51 100.00
36 INT119003 Regulation of Binding of SGCG 1 0.44 0.45 0.1 100.00
37 INT78845 Binding of Pparg 16 0.44 11.67 3.53 100.00
38 INT300643 Positive_regulation of Binding of APOE 1 0.44 0.8 0.09 100.00
39 INT306957 Localization of NAMPT 1 0.70 8.78 0.35 100.00
40 INT94713 Regulation of CD34 11 0.45 8.02 0.58 100.00
41 INT121333 Localization of HEY1 11 0.65 18.17 0.72 100.00
42 INT33735 Binding of ANGPTL5 39 0.32 14.23 3.66 100.00
43 INT124355 Negative_regulation of BEST1 11 0.19 6.13 2.04 100.00
44 INT314777 Negative_regulation of Gene_expression of CST3 1 0.41 1.32 0 100.00
45 INT101172 Localization of Pparg 6 0.58 3.62 0.12 100.00
46 INT202940 Binding of AMD1 13 0.41 16.43 0.56 100.00
47 INT267702 Localization of ARID1B 1 0.29 1.45 0.04 100.00
48 INT174812 Regulation of BEST1 3 0.07 2.4 0.17 100.00
49 INT229014 Binding of Ppard 6 0.21 2.79 0.14 100.00
50 INT229016 Gene_expression of Ppard 3 0.33 1.36 0 100.00
51 INT229011 Localization of Ppard 1 0.33 1.6 0.04 100.00
52 INT38672 Binding of KRT20 69 0.39 48.01 6.31 100.00
53 INT170818 Localization of RASGRP1 4 0.44 1.93 1.02 100.00
54 INT46198 Binding of Hapln1 5 0.31 2.14 0.63 100.00
55 INT200523 Regulation of F7 2 0.01 1.82 0.38 100.00
56 INT230722 Regulation of Hcm 4 0.37 3 0.21 100.00
57 INT330412 Localization of Aldh2 1 0.74 1.3 0.12 100.00
58 INT15684 Positive_regulation of Serpine1 65 0.70 43.51 13.67 99.98
59 INT157463 Gene_expression of CX3CL1 55 0.62 69.05 19.75 99.98
60 INT22984 Positive_regulation of FRTS 12 0.67 5.24 2.25 99.98
61 INT187286 Binding of HEY1 17 0.32 31.21 4.52 99.98
62 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.96
63 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.96
64 INT61423 Gene_expression of Egfl7 23 0.14 24.96 0.66 99.96
65 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 99.96
66 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81 99.96
67 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 99.96
68 INT83190 Gene_expression of Olr1 26 0.59 12.47 2.91 99.96
69 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 99.96
70 INT177642 Positive_regulation of Gene_expression of CENPJ 5 0.30 3.25 0.07 99.96
71 INT50673 Positive_regulation of Gene_expression of CPOX 156 0.54 97.31 37.03 99.96
72 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.92
73 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 99.92
74 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.92
75 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 99.92
76 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 99.92
77 INT14043 Binding of HP 52 0.30 26.56 7.76 99.92
78 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 99.92
79 INT3108 Binding of Tst 11 0.32 13.37 0.77 99.92
80 INT181186 Binding of Rxra 78 0.35 14.93 4.87 99.92
81 INT214045 Negative_regulation of OGG1 5 0.36 3.49 0 99.92
82 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 99.92
83 INT153690 Localization of Hmgcr 1 0.74 1.21 0.06 99.92
84 INT153689 Negative_regulation of Localization of Hmgcr 1 0.42 1.21 0.06 99.92
85 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 99.90
86 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86 99.90
87 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39 99.90
88 INT9648 Positive_regulation of Gene_expression of LPA 15 0.59 11.31 1.72 99.90
89 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 99.88
90 INT27813 Regulation of CENPJ 12 0.29 14.26 0.99 99.88
91 INT156794 Gene_expression of CISH 41 0.58 23.09 5.03 99.88
92 INT148756 Regulation of Adipoq 10 0.60 7.83 0.67 99.88
93 INT93350 Binding of Lepr 17 0.05 27.21 1.5 99.86
94 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54 99.86
95 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 99.84
96 INT75684 Regulation of Aif1 32 0.47 8.03 7.89 99.84
97 INT8068 Gene_expression of RASGRP1 29 0.54 15.1 1.37 99.84
98 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 99.84
99 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 99.82
100 INT34585 Negative_regulation of Positive_regulation of HSD11B1 31 0.57 43.54 2.47 99.82
101 INT249471 Binding of BMF 1 0.30 1.3 0 99.82
102 INT88000 Gene_expression of LAP 15 0.55 6.94 0.91 99.80
103 INT154104 Binding of ARID1B 47 0.39 69.82 1.49 99.80
104 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52 99.80
105 INT229632 Binding of PADI4 21 0.48 37.45 0.34 99.80
106 INT101027 Binding of DST 20 0.41 10.9 1.17 99.80
107 INT9466 Binding of APOB 27 0.41 19.36 1.56 99.80
108 INT259241 Negative_regulation of ED 3 0.37 5.09 0.34 99.80
109 INT83431 Binding of ADIPOQ 35 0.48 33.63 3.83 99.80
110 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56 99.80
111 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72 99.80
112 INT343946 Gene_expression of Hgs 2 0.41 1.59 1.35 99.80
113 INT204124 Transcription of CRP 14 0.69 20.79 2.71 99.80
114 INT339080 Positive_regulation of Binding of PADI4 1 0.03 1.3 0 99.80
115 INT323285 Localization of EPHX2 1 0.12 1.02 0 99.80
116 INT267701 Positive_regulation of Binding of ARID1B 1 0.19 2.83 0 99.80
117 INT277049 Regulation of Binding of APOB 1 0.27 0.91 0.16 99.80
118 INT88001 Binding of LAP 6 0.45 7.85 0.07 99.76
119 INT71418 Binding of CES1 42 0.40 29.78 5.01 99.76
120 INT14572 Binding of INS 205 0.48 175.43 13.38 99.76
121 INT86437 Binding of IL6 154 0.48 121.22 29.3 99.76
122 INT259240 Binding of ED 2 0.32 12.98 1.04 99.76
123 INT54763 Binding of Il6 82 0.48 63.27 12.89 99.76
124 INT198961 Gene_expression of SPINK7 5 0.18 6.02 0.05 99.76
125 INT45613 Positive_regulation of pad 23 0.50 24.18 4.8 99.76
126 INT62570 Binding of Pth 48 0.48 26.45 4.85 99.76
127 INT170738 Binding of Icam1 23 0.37 25.49 4.09 99.76
128 INT3364 Binding of SGCG 87 0.47 31.93 17.24 99.76
129 INT128609 Gene_expression of C1S 18 0.75 17.36 0.98 99.76
130 INT181868 Localization of ACLY 5 0.62 6.36 1.4 99.76
131 INT23199 Binding of LDLR 22 0.47 17.08 1.16 99.76
132 INT50080 Binding of APOE 38 0.45 29.61 2.67 99.76
133 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.76
134 INT183276 Negative_regulation of Adrm1 10 0.04 7.25 1.74 99.76
135 INT146024 Negative_regulation of Ped 4 0.16 3.06 1.12 99.76
136 INT132471 Regulation of Peg10 5 0.06 2.81 0.13 99.76
137 INT332611 Regulation of Regulation of Peg10 1 0.00 0.62 0 99.76
138 INT178890 Localization of CHDH 12 0.62 15.76 1.49 99.74
139 INT227663 Localization of IDS 14 0.63 7.64 1.85 99.74
140 INT171252 Gene_expression of BMI1 21 0.70 26.98 4.11 99.70
141 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 99.68
142 INT37800 Positive_regulation of Apob 7 0.18 11.01 0.48 99.68
143 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 99.68
144 INT70789 Negative_regulation of Agtrap 26 0.48 16.39 2.18 99.68
145 INT174099 Gene_expression of RNH1 11 0.28 4.03 0.71 99.68
146 INT90766 Gene_expression of PCS 93 0.77 40.48 14.51 99.68
147 INT36142 Negative_regulation of Hmgcr 33 0.46 15.91 3.54 99.68
148 INT26863 Regulation of Vms1 7 0.09 2.67 2.23 99.68
149 INT153688 Negative_regulation of Negative_regulation of Hmgcr 1 0.42 1.21 0.06 99.68
150 INT239219 Localization of Agtrap 2 0.50 5.81 0.06 99.68
151 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.64
152 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.64
153 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08 99.64
154 INT112665 Gene_expression of TRAF2 3 0.29 3.97 0.61 99.64
155 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 99.64
156 INT39712 Binding of pad 82 0.48 110.92 10.33 99.62
157 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 99.60
158 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95 99.60
159 INT11069 Positive_regulation of Pf4 35 0.68 27.7 13.96 99.60
160 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 99.60
161 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 99.60
162 INT61420 Positive_regulation of Gene_expression of Egfl7 20 0.12 18.96 0.13 99.60
163 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 99.60
164 INT53080 Positive_regulation of Ptgs1 42 0.42 23.58 14.37 99.60
165 INT138843 Binding of CC2D1A 19 0.33 33.06 1.25 99.60
166 INT133561 Regulation of Binding of F13A1 3 0.36 2.72 0.42 99.58
167 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 99.56
168 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.56
169 INT352803 Positive_regulation of FGF21 1 0.66 18.41 0.14 99.56
170 INT234 Binding of Alb 151 0.48 52.34 32.97 99.56
171 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03 99.56
172 INT92619 Binding of LCT 4 0.48 2.32 0.14 99.56
173 INT17474 Negative_regulation of Positive_regulation of LDLR 4 0.37 2.93 0.16 99.56
174 INT9079 Gene_expression of PPBP 52 0.75 31.2 21.52 99.56
175 INT173979 Gene_expression of Cap1 3 0.42 2.17 0.22 99.56
176 INT155992 Gene_expression of THBD 16 0.66 17 1.24 99.54
177 INT17685 Negative_regulation of Cog1 23 0.42 15.65 3.56 99.54
178 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12 99.54
179 INT67980 Positive_regulation of Positive_regulation of CCL2 7 0.49 5.89 1.85 99.54
180 INT92822 Negative_regulation of Gene_expression of Crp 36 0.49 29.5 8.83 99.54
181 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.52
182 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.52
183 INT812 Localization of INS 1026 0.81 515.6 145.31 99.52
184 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 99.52
185 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 99.52
186 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 99.52
187 INT191783 Positive_regulation of Pnp 21 0.67 22.51 1.66 99.52
188 INT32692 Positive_regulation of Aif1 33 0.35 13.29 9.03 99.52
189 INT111514 Positive_regulation of Gene_expression of Mpo 20 0.49 15.13 3.88 99.52
190 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42 99.52
191 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 99.52
192 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 99.50
193 INT166356 Negative_regulation of HSPD1 4 0.55 3 0.23 99.50
194 INT107926 Negative_regulation of CP 9 0.41 4.37 0.21 99.50
195 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 99.50
196 INT127022 Gene_expression of Lts1 43 0.23 28.29 12.64 99.50
197 INT3128 Negative_regulation of PON1 30 0.59 26.19 4.57 99.48
198 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 99.48
199 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 99.48
200 INT190691 Negative_regulation of APOA1 12 0.42 15.9 0.39 99.48
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