D:Cataract

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pChart

Disease Term
Synonyms Cataract Membranous, Cataracts, Cataracts Membranous, Central Cataract, Degenerative Opacity, Diabetic Cataract, LENS OPACITIES, Lens Opacity, Membranous Cataract, Membranous Cataracts, NUCLEAR CATARACT
Documents 1897
Hot Single Events 200
Hot Interactions 49

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cataract. They are ordered first by their relevance to Cataract and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT347295 CCL16 Positive_regulation of Gene_expression of AKT1 1 0.12 0.29 0.03 100.00
2 INT347294 CCL16 Positive_regulation of Binding of ITK 1 0.02 0.78 0 99.50
3 INT273772 BCKDHA Positive_regulation of Positive_regulation of NARFL 1 0.03 1.21 0 99.20
4 INT328422 Protein_catabolism of Neu1 Positive_regulation of Dnase2b 1 0.01 0.67 0 97.44
5 INT192044 Binding of DSP and Jup 2 0.24 2.39 0 97.40
6 INT192048 Binding of DSP and Ryr2 1 0.24 1.1 0 97.40
7 INT192042 Binding of Jup and Ryr2 1 0.17 1.09 0 97.40
8 INT328424 Negative_regulation of lec Negative_regulation of Positive_regulation of Ros1 1 0.21 0.34 0 96.80
9 INT342231 Binding of SEPP1 and ARC 1 0.04 3.84 0.08 96.40
10 INT342234 Binding of SEPP1 and PKD1P4 1 0.00 2.55 0 96.40
11 INT314867 Binding of Cdc7 and Cdkn2b 1 0.25 1.16 0.14 95.48
12 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14 95.48
13 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14 95.20
14 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14 95.20
15 INT285077 CCL16 Positive_regulation of ITK 1 0.05 1.95 0.31 94.88
16 INT230336 IL4 Regulation of IL5 2 0.04 0.82 0.67 94.56
17 INT292893 TNF Regulation of IL8 2 0.27 1.3 0.63 94.56
18 INT292887 IL4 Regulation of IL12A 1 0.01 0.25 0.39 94.56
19 INT292891 IL2 Regulation of IL5 1 0.02 0.25 0.39 94.56
20 INT292892 IL4 Regulation of IL8 1 0.01 0.25 0.39 94.56
21 INT292889 IL2 Regulation of IL12A 1 0.01 0.25 0.39 94.56
22 INT292890 TNF Regulation of IL5 1 0.02 0.25 0.39 94.56
23 INT292888 TNF Regulation of IL12A 1 0.02 0.25 0.39 94.56
24 INT292886 IL2 Regulation of IL8 1 0.03 0.25 0.39 94.56
25 INT342230 Binding of ARC and PKD1P4 1 0.01 5.72 0.07 94.32
26 INT77098 Nlrp1a Negative_regulation of Positive_regulation of Ppig 1 0.47 0.68 0.53 93.88
27 INT225983 Binding of lec and Ros1 1 0.10 0.51 0 93.84
28 INT347302 PDGFA Positive_regulation of ITK 1 0.04 1.4 0.09 91.64
29 INT251347 Binding of Bmpr2 and Limk1 1 0.18 1.51 0.16 91.04
30 INT285070 CCL16 Positive_regulation of Gene_expression of CYP19A1 1 0.02 0.69 0.09 90.00
31 INT192046 Negative_regulation of Binding of RYR2 and Cbx5 1 0.01 1.12 0 88.32
32 INT192049 Negative_regulation of Binding of RYR2 and Cbx1 1 0.01 1.12 0 88.32
33 INT192047 Binding of RYR2 and Cbx1 1 0.01 1.12 0 88.32
34 INT192043 Binding of RYR2 and Cbx5 1 0.01 1.12 0 88.32
35 INT285071 EGF Positive_regulation of CCL16 1 0.03 0.77 0 87.88
36 INT285072 EGF Positive_regulation of ITK 1 0.03 0.77 0 87.88
37 INT285074 Positive_regulation of ITK Regulation of CCL16 1 0.04 0.77 0 86.24
38 INT352392 Binding of ENOSF1 and Recql4 1 0.02 6.62 0 86.04
39 INT285068 ITK Regulation of CCL16 1 0.02 1.86 0.03 85.96
40 INT285076 CCL16 Positive_regulation of Gene_expression of ITK 1 0.05 1.8 0.14 85.68
41 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43 85.04
42 INT262940 Regulation of Binding of PAX6 and SIX3 1 0.16 0.91 0 84.24
43 INT262943 Regulation of Binding of PAX6 and SOX2 1 0.17 0.91 0 84.24
44 INT262938 Binding of PAX6 and SIX3 1 0.13 0.9 0 83.68
45 INT262942 Binding of PAX6 and SOX2 1 0.18 0.9 0 83.68
46 INT251349 Ifnar1 Positive_regulation of Rock1 1 0.01 1.27 0.16 83.04
47 INT251348 Ifnar1 Positive_regulation of Limk2 1 0.01 1.12 0.11 83.04
48 INT285067 Negative_regulation of ITK Regulation of CCL16 1 0.04 1.1 0.03 82.44
49 INT353104 Binding of amd and Gtf3a 1 0.01 1.53 0.03 80.32
50 INT225620 Gene_expression of IGHD6-13 Negative_regulation of Binding of Asc2 1 0.12 0.87 0 78.84
51 INT347292 AREG Negative_regulation of Gene_expression of TERT 1 0.02 0.78 0 78.40
52 INT234801 RAB3GAP1 Regulation of RAB3A 1 0.08 1.64 0.15 77.12
53 INT272522 Celf1 Positive_regulation of Phosphorylation of CEBPD 1 0.03 0.52 0 74.80
54 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8 73.88
55 INT300449 VEGFA Positive_regulation of Protein_catabolism of Ppp2r2b 1 0.00 1.51 0.05 73.60
56 INT340439 Binding of HLA-DMA and SUGT1 1 0.00 4.1 1.16 73.08
57 INT340438 Binding of HLA-DMA and MRAP 1 0.02 1.69 0.43 73.08
58 INT347298 AREG Negative_regulation of TEP1 1 0.00 0.79 0 71.76
59 INT234800 RAB27A Positive_regulation of INS 1 0.02 1.26 0 69.96
60 INT234793 RAB27A Positive_regulation of Localization of INS 1 0.03 1.26 0 69.96
61 INT225542 Binding of D0Nrs1 and Asc2 1 0.01 0.63 0 67.84
62 INT225601 Binding of D0Nrs1 and Ncoa6 1 0.04 0.84 0 67.84
63 INT347297 ILK Regulation of Gene_expression of AKT1 1 0.21 0.62 0 63.56
64 INT294608 Binding of Serpinh1 and Col5a1 1 0.03 0.45 0.09 62.56
65 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 61.12
66 INT225545 Negative_regulation of Binding of nr and Asc2 1 0.03 0.79 0 60.24
67 INT225509 Negative_regulation of Binding of nr and Ncoa6 1 0.11 0.79 0 60.24
68 INT225609 Negative_regulation of Binding of Ncoa6 and Asc2 1 0.14 0.79 0 60.24
69 INT225600 Binding of Ncoa6 and Asc2 1 0.12 0.78 0 59.68
70 INT225552 Binding of nr and Ncoa6 1 0.09 1.04 0 59.68
71 INT225519 Binding of nr and Asc2 1 0.04 0.78 0 59.44
72 INT347290 Positive_regulation of CCL16 Positive_regulation of PIK3CB 1 0.03 0.57 0 50.68
73 INT347303 Positive_regulation of CCL16 Positive_regulation of AKT1 1 0.08 0.57 0 50.68
74 INT286268 Binding of GSR and Gpx1 2 0.02 0 0 50.00
75 INT340380 Binding of Cfl1 and Clcn4-2 1 0.13 0.82 0 48.04
76 INT340377 Binding of Clcn4-2 and Clcn5 1 0.35 0.82 0 48.04
77 INT340378 Binding of Cfl1 and Clcn5 1 0.15 0.82 0 47.64
78 INT267116 Binding of Lmx1b and Nps 1 0.30 1.95 0 46.20
79 INT311298 Binding of DMPK and Mbnl1 1 0.43 0.54 0 44.48
80 INT233397 Binding of ABCA4 and COL2A1 1 0.38 3.59 0.03 43.84
81 INT347304 PDGFA Positive_regulation of Gene_expression of AKT1 1 0.19 0.6 0 43.24
82 INT347296 PDGFA Positive_regulation of CCL16 1 0.06 0.6 0 43.24
83 INT174104 Binding of HSPG2 and Ache 1 0.16 0.98 0.09 41.52
84 INT272524 DICER1 Negative_regulation of Dmpk 1 0.04 0.07 0 40.44
85 INT314866 Binding of Six1 and Sall1 1 0.39 0.76 0 40.12
86 INT267115 Lmx1b Regulation of Gene_expression of Col4a1 1 0.09 1.37 0 37.12
87 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73 34.96
88 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73 34.96
89 INT234802 Binding of AQP2 and AVPR2 2 0.15 0.84 0.07 34.96
90 INT234791 Binding of AVP and AVPR2 1 0.14 0.55 0 34.96
91 INT234796 Binding of AQP2 and AVP 1 0.15 1.1 0 34.96
92 INT322734 Binding of CD40LG and Positive_regulation of CD40 1 0.07 0.62 0.18 30.88
93 INT311390 Mbnl1 Positive_regulation of Celf1 1 0.26 0.48 0 30.32
94 INT322733 CD40LG Positive_regulation of Gene_expression of CD40 1 0.08 0.62 0.18 30.16
95 INT267117 Lmx1b Regulation of Col7a1 1 0.02 1.29 0 28.08
96 INT234831 Binding of SPTLC1 and Abo 1 0.00 1.61 0.23 27.92
97 INT300445 VEGFA Positive_regulation of Vegfa 1 0.03 1.33 0.03 24.00
98 INT342229 SEPP1 Regulation of ARC 1 0.03 0.44 0 23.68
99 INT342228 PKD1P4 Regulation of ARC 1 0.00 0.44 0 23.68
100 INT306339 Binding of CRX and PAX6 1 0.53 0.27 0 22.68
101 INT288026 PROC Positive_regulation of Gene_expression of VEGFA 1 0.01 0.5 0.15 21.44
102 INT339581 Binding of TIMP1 and TIMP3 1 0.30 0.54 0 21.20
103 INT300446 VEGFA Positive_regulation of Flt1 1 0.09 2.62 0.07 21.12
104 INT340437 Binding of SERPINH1 and HLA-DRB4 1 0.00 2.26 0.84 19.20
105 INT347577 Binding of MUC1 and MUC16 1 0.25 0.42 0 18.88
106 INT286476 Binding of App and Itm2b 1 0.47 5.24 0.14 17.48
107 INT234797 AVP Regulation of GOPC 1 0.01 0.65 0 14.48
108 INT234803 AVP Regulation of AQP2 1 0.11 1.3 0 14.28
109 INT272523 Binding of DMPK and Gtf3a 1 0.00 0.81 0 14.00
110 INT272521 Binding of DMPK and Nkx2-5 1 0.01 0.42 0 14.00
111 INT339580 TIMP3 Positive_regulation of ABCA1 1 0.16 0.73 0 7.36
112 INT339586 TIMP3 Positive_regulation of RPE 1 0.16 0.72 0 5.68
113 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
114 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 5.00
115 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
116 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16 5.00
117 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93 5.00
118 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91 5.00
119 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
120 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
121 INT185358 Binding of MCS and PCS 7 0.22 3.34 0.57 5.00
122 INT263776 Grin1 Positive_regulation of Ltp 2 0.17 0.17 0.54 5.00
123 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 5.00
124 INT289464 Negative_regulation of IRF6 Positive_regulation of ICAM1 1 0.07 0.31 0.5 5.00
125 INT289462 Negative_regulation of IRF6 Positive_regulation of IL1B 2 0.04 0.31 0.48 5.00
126 INT289463 IRF6 Positive_regulation of Localization of IL1B 1 0.05 0.52 0.48 5.00
127 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48 5.00
128 INT268473 Negative_regulation of CNR1 Negative_regulation of Cysltr1 1 0.00 1.02 0.48 5.00
129 INT340440 Binding of HLA-B and BTG3 1 0.05 1.57 0.47 5.00
130 INT125568 Binding of Casr and Ncoa6 3 0.50 1.13 0.46 5.00
131 INT183322 Binding of CNNM4 and RBM4B 1 0.12 0.59 0.46 5.00
132 INT262815 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.39 2.73 0.44 5.00
133 INT352972 IL4 Negative_regulation of Gene_expression of IL8 1 0.07 1.01 0.43 5.00
134 INT352986 IL10 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
135 INT352985 IL4 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
136 INT262819 Gene_expression of Serpinf1 Negative_regulation of Binding of 1190002H23Rik 1 0.05 2.66 0.43 5.00
137 INT352970 IL4 Negative_regulation of Positive_regulation of TH1L 1 0.01 0.91 0.4 5.00
138 INT171990 Binding of DMD and VDR 5 0.05 2.58 0.39 5.00
139 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38 5.00
140 INT262824 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.39 1.56 0.37 5.00
141 INT224423 Binding of TNFRSF11B and TNFRSF11A 3 0.19 2.36 0.37 5.00
142 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34 5.00
143 INT210597 Negative_regulation of Binding of TNFSF11 and TNFRSF11A 3 0.26 5.66 0.33 5.00
144 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33 5.00
145 INT267123 ROS1 Positive_regulation of Positive_regulation of Nfkb1 1 0.01 1.05 0.31 5.00
146 INT187361 Binding of Gabrg1 and Kcnn3 1 0.36 0.13 0.3 5.00
147 INT347531 Binding of Nrp2 and Sema3b 1 0.04 0.99 0.28 5.00
148 INT262826 Serpinf1 Negative_regulation of Gene_expression of TNF 1 0.29 1.83 0.28 5.00
149 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27 5.00
150 INT262820 Binding of Aif1 and Serpinf1 1 0.01 1.3 0.27 5.00
151 INT230748 Agtr2 Positive_regulation of Gene_expression of Ros1 2 0.05 1.04 0.23 5.00
152 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22 5.00
153 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22 5.00
154 INT262817 Serpinf1 Regulation of Positive_regulation of 1190002H23Rik 1 0.06 1.3 0.22 5.00
155 INT289997 CNTF Negative_regulation of Binding of CNTF and Casp3 1 0.05 0.99 0.22 5.00
156 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22 5.00
157 INT214481 ROS1 Negative_regulation of Gene_expression of INS 1 0.00 0.37 0.22 5.00
158 INT318303 Negative_regulation of Myoz1 Negative_regulation of Transcription of IL2 1 0.00 0.75 0.21 5.00
159 INT304882 Agtr2 Positive_regulation of Mapk1 1 0.07 0.95 0.2 5.00
160 INT256629 Binding of Ptch1 and Shh 7 0.42 4.22 0.19 5.00
161 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18 5.00
162 INT198700 Binding of DSG3 and Pv 1 0.15 1.45 0.18 5.00
163 INT262818 Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.45 0.71 0.18 5.00
164 INT262822 Serpinf1 Negative_regulation of Negative_regulation of 1190002H23Rik 1 0.07 1.27 0.18 5.00
165 INT229928 Binding of C3 and CFH 1 0.07 1.35 0.17 5.00
166 INT225607 Ncoa6 Regulation of Gene_expression of Casr 1 0.15 0.68 0.17 5.00
167 INT229931 Negative_regulation of Binding of C3 and CFH 1 0.08 1.35 0.17 5.00
168 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16 5.00
169 INT225501 Plcl1 Regulation of Gene_expression of Casr 1 0.04 0.67 0.16 5.00
170 INT347301 AREG Positive_regulation of CCL16 1 0.01 0.86 0.16 5.00
171 INT225608 Ppara Regulation of Ncoa6 1 0.27 0.44 0.14 5.00
172 INT214480 SELPLG Negative_regulation of Positive_regulation of NFKB1 1 0.00 0.6 0.14 5.00
173 INT184704 Binding of Prrx2 and Sr1 1 0.21 1.65 0.13 5.00
174 INT354888 Amy1 Regulation of Il10 1 0.02 1.41 0.13 5.00
175 INT354885 Amy1 Regulation of Gene_expression of Il10 1 0.03 1.41 0.13 5.00
176 INT349274 Binding of CGF1 and NOS1 1 0.00 2.97 0.12 5.00
177 INT311399 Binding of Celf1 and Uts2r 1 0.08 0.26 0.12 5.00
178 INT212139 Slc4a3 Positive_regulation of Cl 1 0.07 0 0.12 5.00
179 INT212138 Slc4a3 Positive_regulation of Gene_expression of Cl 1 0.07 0 0.12 5.00
180 INT304881 Ros1 Positive_regulation of Mapk1 1 0.25 0.36 0.1 5.00
181 INT199436 Binding of Capns1 and Cysltr1 1 0.00 0.79 0.1 5.00
182 INT304887 Agtr2 Positive_regulation of Positive_regulation of Mapk1 1 0.10 0.45 0.09 5.00
183 INT304886 Agtr2 Positive_regulation of Ros1 1 0.03 0.45 0.09 5.00
184 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
185 INT304883 Agtr2 Positive_regulation of Agtrap 1 0.10 0.46 0.09 5.00
186 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
187 INT342232 Binding of POR and SEPP1 1 0.02 0.75 0.08 5.00
188 INT304884 Agtrap Positive_regulation of Gene_expression of Ros1 1 0.17 0.48 0.08 5.00
189 INT262939 PAX6 Regulation of CDH4 1 0.02 0.97 0.08 5.00
190 INT262937 PAX6 Regulation of CDH8 1 0.03 0.98 0.08 5.00
191 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08 5.00
192 INT262825 Serpinf1 Negative_regulation of Gfap 1 0.34 0.87 0.08 5.00
193 INT262944 PAX6 Regulation of CDH6 1 0.03 0.97 0.08 5.00
194 INT250024 Positive_regulation of Ros1 Positive_regulation of Gtf3a 1 0.00 1.26 0.08 5.00
195 INT250023 Positive_regulation of Ros1 Positive_regulation of Nfkb1 1 0.04 1.26 0.08 5.00
196 INT262821 Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.54 0.85 0.08 5.00
197 INT225494 Binding of Casr and Asc2 1 0.03 0.63 0.07 5.00
198 INT278441 Lbp Positive_regulation of Gene_expression of ITGAX 1 0.44 1.18 0.07 5.00
199 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06 5.00
200 INT229977 Binding of amd and Cfb 1 0.03 2.78 0.06 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cataract. They are ordered first by their pain relevance and then by number of times they were reported in Cataract. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT209912 Gene_expression of Pycard 17 0.22 12.04 1.04 100.00
2 INT262796 Positive_regulation of Pycard 12 0.22 6.5 0.14 100.00
3 INT216978 Binding of Pycard 6 0.25 2.93 0.22 100.00
4 INT64373 Binding of lop2 1 0.02 0.82 0.14 100.00
5 INT262801 Regulation of Gene_expression of Pycard 1 0.08 1.8 0.04 100.00
6 INT209911 Protein_catabolism of Pycard 2 0.11 1.58 0.33 100.00
7 INT262800 Positive_regulation of Binding of Pycard 1 0.09 0.75 0 100.00
8 INT342241 Binding of SEPP1 1 0.47 3.08 0 100.00
9 INT20966 Positive_regulation of Arc 30 0.70 24.38 15.62 100.00
10 INT262799 Localization of Smad3 6 0.56 2.09 0.04 100.00
11 INT262795 Localization of Pycard 2 0.26 1.61 0 100.00
12 INT353099 Positive_regulation of Ctrcts 1 0.01 1.63 0.16 100.00
13 INT297322 Binding of Apoa2 3 0.36 1.7 0.27 100.00
14 INT309803 Negative_regulation of Binding of Apoa2 1 0.41 1.02 0 100.00
15 INT309802 Positive_regulation of Binding of Apoa2 1 0.49 1.03 0 100.00
16 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 99.96
17 INT27882 Gene_expression of HSP90B2P 52 0.75 36.51 9.59 99.92
18 INT58107 Negative_regulation of MPG 2 0.41 0.92 0.98 99.92
19 INT85302 Negative_regulation of Cyp2b21 6 0.20 8.94 1.8 99.90
20 INT28853 Negative_regulation of lec 16 0.46 6.17 0.16 99.90
21 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57 99.90
22 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01 99.88
23 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04 99.86
24 INT3846 Positive_regulation of GSR 60 0.50 35.16 9.37 99.86
25 INT101689 Positive_regulation of Cyp2b21 3 0.23 3.65 0.86 99.80
26 INT93350 Binding of Lepr 17 0.05 27.21 1.5 99.80
27 INT19153 Gene_expression of lec 7 0.59 2.89 0.69 99.78
28 INT346921 Negative_regulation of NFIC 1 0.11 1.9 0 99.76
29 INT239497 Binding of Aes 8 0.29 3.61 0.84 99.76
30 INT273158 Binding of COL8A2 1 0.33 2.02 0.22 99.76
31 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 99.72
32 INT229940 Positive_regulation of amd 10 0.49 27.97 0.15 99.72
33 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16 99.70
34 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 99.66
35 INT61938 Negative_regulation of Pxk 5 0.36 3.05 1.2 99.66
36 INT209355 Binding of SLC9A6 8 0.42 14.9 0.09 99.64
37 INT269743 Positive_regulation of Binding of BPHL 1 0.19 2.94 0.13 99.64
38 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 99.60
39 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 99.60
40 INT52924 Negative_regulation of GSR 49 0.58 28.08 9.28 99.58
41 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 99.54
42 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 99.52
43 INT294606 Negative_regulation of Positive_regulation of Serpinh1 1 0.09 2.69 0.09 99.48
44 INT294609 Negative_regulation of Gene_expression of HSP90B2P 1 0.05 2.68 0.09 99.48
45 INT294605 Negative_regulation of Gene_expression of Serpinh1 1 0.13 2.68 0.09 99.48
46 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83 99.48
47 INT107593 Regulation of Ecd 2 0.21 1.16 0.23 99.44
48 INT328418 Protein_catabolism of Dnase2b 1 0.42 0.72 0 99.40
49 INT202940 Binding of AMD1 13 0.41 16.43 0.56 99.40
50 INT103942 Binding of BPHL 11 0.30 14.26 0.53 99.40
51 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 99.36
52 INT77076 Positive_regulation of Ppig 16 0.49 13.54 5.91 99.36
53 INT77093 Positive_regulation of Serpina3c 1 0.67 1.31 0.95 99.36
54 INT182229 Positive_regulation of CCL16 15 0.66 12.19 8.21 99.36
55 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.34
56 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 99.34
57 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.34
58 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 99.32
59 INT17561 Localization of Car2 303 0.79 60.95 44.52 99.32
60 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 99.32
61 INT79902 Gene_expression of AQP1 33 0.78 24.72 4.55 99.32
62 INT134968 Localization of Ecm1 20 0.32 27.27 4.31 99.30
63 INT197973 Localization of Col4a1 2 0.73 2.15 0.26 99.30
64 INT5409 Negative_regulation of G6pd 33 0.57 29.21 7.64 99.28
65 INT5410 Gene_expression of G6pd 15 0.75 4.59 1.28 99.28
66 INT328420 Regulation of lec 1 0.26 0.38 0 99.28
67 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 99.28
68 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 99.20
69 INT347160 Gene_expression of Cyp2b21 1 0.23 1.16 0 99.20
70 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 99.18
71 INT49292 Positive_regulation of Cyp1a2 17 0.69 6.16 4.96 99.18
72 INT297602 Positive_regulation of Tsv 3 0.07 3.36 0.33 99.12
73 INT109910 Gene_expression of CCL16 104 0.74 76.1 43.97 99.10
74 INT269226 Positive_regulation of ITK 13 0.12 11.23 0.4 99.08
75 INT85624 Gene_expression of GJB1 5 0.78 3.03 0.93 99.08
76 INT140794 Gene_expression of Smad3 22 0.64 9.41 0.83 99.04
77 INT262797 Regulation of Gene_expression of Smad3 2 0.34 2.27 0.25 99.04
78 INT285094 Binding of ITK 4 0.11 2.14 0.05 99.02
79 INT73984 Positive_regulation of Serpinh1 2 0.35 5.92 0.1 98.92
80 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 98.88
81 INT5412 Regulation of G6pd 9 0.62 1.64 2.87 98.88
82 INT219224 Gene_expression of Ighv10-3 1 0.03 12.91 0.07 98.80
83 INT91070 Regulation of GSR 27 0.59 16.64 3.42 98.80
84 INT259471 Localization of LAMA3 1 0.52 0.76 0.03 98.80
85 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 98.76
86 INT101866 Positive_regulation of Gene_expression of AKT1 49 0.52 17.47 2.14 98.76
87 INT51316 Regulation of NR3C1 7 0.51 4.23 2.09 98.72
88 INT139863 Binding of amd 27 0.41 41.3 0.91 98.66
89 INT260527 Negative_regulation of AMD1 6 0.37 5 0.05 98.64
90 INT269748 Positive_regulation of AMD1 4 0.43 3.56 0.28 98.64
91 INT118124 Binding of USE1 24 0.16 16.64 5.44 98.64
92 INT104567 Gene_expression of Aqp1 47 0.78 44.84 28.68 98.60
93 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 98.58
94 INT211586 Regulation of DMPK 6 0.31 2.11 0.33 98.56
95 INT19342 Regulation of Insr 12 0.24 6.11 1.54 98.56
96 INT235683 Regulation of Clcn1 4 0.21 1.49 0.03 98.56
97 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53 98.52
98 INT233399 Binding of ABCA4 9 0.46 9.49 0.07 98.52
99 INT272511 Positive_regulation of DMPK 8 0.54 6.85 0.72 98.48
100 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 98.44
101 INT90604 Positive_regulation of Positive_regulation of Ahr 8 0.45 3.52 1.45 98.44
102 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73 98.44
103 INT84700 Positive_regulation of HSP90B2P 34 0.67 30.22 4.07 98.36
104 INT55434 Positive_regulation of Gene_expression of HSP90B2P 14 0.38 10.91 4.83 98.36
105 INT197395 Positive_regulation of Gene_expression of Serpinh1 2 0.19 2.81 0.07 98.36
106 INT104564 Gene_expression of Aqp3 8 0.65 4.92 1.99 98.28
107 INT198453 Negative_regulation of MUC5AC 12 0.58 12.96 1.38 98.28
108 INT69867 Gene_expression of Mip 36 0.75 24.54 10.38 98.28
109 INT192533 Positive_regulation of CLTA 4 0.13 4.98 0.1 98.28
110 INT287404 Negative_regulation of Capn3 1 0.40 0.15 0 98.28
111 INT23045 Positive_regulation of Hbb 31 0.64 19.35 4.54 98.24
112 INT321381 Localization of Arih2 1 0.08 1.63 0.08 98.24
113 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 98.24
114 INT5411 Positive_regulation of G6pd 20 0.70 4.74 5.11 98.12
115 INT214735 Gene_expression of IGHD1-7 5 0.57 3.28 0.14 98.12
116 INT192975 Localization of SLC9A6 7 0.43 14.24 0.24 98.08
117 INT1539 Positive_regulation of MSMB 22 0.69 9.42 4.62 98.08
118 INT109917 Positive_regulation of Gene_expression of CCL16 17 0.66 11.87 2.94 98.04
119 INT291914 Negative_regulation of Localization of Ros1 5 0.34 1.36 0.84 98.04
120 INT73977 Gene_expression of Serpinh1 14 0.54 8.14 0.69 97.96
121 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 97.96
122 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 97.96
123 INT19044 Positive_regulation of GGT5 10 0.65 7.7 1.11 97.88
124 INT1114 Localization of Ins1 748 0.80 192.95 165.48 97.84
125 INT17349 Negative_regulation of Akr1b1 41 0.59 27.03 10.65 97.80
126 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61 97.72
127 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 97.72
128 INT38672 Binding of KRT20 69 0.39 48.01 6.31 97.60
129 INT40698 Positive_regulation of Aes 3 0.32 3.84 0.65 97.60
130 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 97.56
131 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66 97.56
132 INT100821 Localization of Ros1 59 0.60 45.26 11.92 97.52
133 INT267894 Gene_expression of ITK 13 0.57 9.71 0.9 97.44
134 INT328421 Protein_catabolism of Neu1 1 0.02 0.67 0 97.44
135 INT328419 Positive_regulation of Protein_catabolism of Neu1 1 0.01 0.67 0 97.44
136 INT112837 Regulation of GPX1 3 0.17 1.81 0.25 97.44
137 INT178813 Gene_expression of ARC 9 0.67 10.78 0.43 97.36
138 INT115528 Binding of Ros1 37 0.41 22.96 5.5 97.06
139 INT180451 Positive_regulation of Apoa2 15 0.67 12.65 0.89 97.00
140 INT180454 Negative_regulation of Apoa2 6 0.42 7.42 0.2 97.00
141 INT173537 Binding of CCL16 18 0.40 13.02 7.36 96.92
142 INT109470 Negative_regulation of ITK 3 0.24 2.13 0.96 96.92
143 INT285097 Negative_regulation of CCL16 3 0.13 3.88 0.24 96.76
144 INT113641 Negative_regulation of Gene_expression of GP1BA 4 0.57 2.2 0.44 96.76
145 INT269220 Positive_regulation of Gene_expression of ITK 4 0.14 3.07 0.41 96.60
146 INT243210 Negative_regulation of Gene_expression of Ecm1 3 0.05 3.1 0 96.60
147 INT210673 Gene_expression of Gpx4 2 0.48 3.54 0.09 96.50
148 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 96.36
149 INT99615 Gene_expression of GP1BA 12 0.75 2.98 0.5 96.36
150 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23 96.16
151 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 96.08
152 INT184678 Regulation of Uts2r 7 0.14 2.57 0.85 96.04
153 INT108380 Regulation of Cyp2b21 1 0.21 1.24 0.16 96.00
154 INT117754 Gene_expression of NHS 34 0.57 9.27 3.28 96.00
155 INT225976 Negative_regulation of Negative_regulation of lec 1 0.34 0.35 0 95.96
156 INT273079 Negative_regulation of Gene_expression of P2RY2 1 0.59 0.52 0.09 95.96
157 INT239498 Localization of Aes 2 0.58 2.22 0.4 95.92
158 INT159425 Positive_regulation of Cd320 11 0.67 9.35 0.11 95.92
159 INT286267 Positive_regulation of Negative_regulation of GSR 1 0.12 0.9 0.33 95.88
160 INT258059 Negative_regulation of Positive_regulation of GSR 3 0.41 1.79 0.33 95.88
161 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 95.84
162 INT148022 Gene_expression of CND 1 0.52 0.15 0 95.84
163 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 95.80
164 INT251238 Gene_expression of Lvs 35 0.32 29.41 1.59 95.80
165 INT104566 Negative_regulation of Aqp2 3 0.44 1.23 0.11 95.52
166 INT169670 Gene_expression of PHARC 1 0.14 1.41 0.35 95.48
167 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 95.44
168 INT105816 Gene_expression of P2RY2 53 0.78 16.47 9.67 95.40
169 INT113 Positive_regulation of MBD2 33 0.49 6.76 7.49 95.32
170 INT185443 Regulation of ROCK1 4 0.18 3.32 0.21 95.28
171 INT19716 Gene_expression of Ecd 9 0.41 2.18 0.57 95.24
172 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 95.20
173 INT85328 Negative_regulation of Aqp1 5 0.54 6.02 4.94 95.20
174 INT241687 Binding of Cdkn2a 5 0.31 5.26 0.18 95.20
175 INT235796 Positive_regulation of Binding of amd 2 0.21 2.76 0.04 95.16
176 INT342238 Negative_regulation of ARC 1 0.32 2.05 0 95.12
177 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 95.12
178 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5 95.12
179 INT130560 Negative_regulation of Gene_expression of Serpinf1 17 0.58 13.39 1.94 95.08
180 INT108203 Negative_regulation of Gene_expression of AKT1 28 0.54 16.38 3.19 95.00
181 INT69776 Positive_regulation of cy 1 0.05 0.17 0.35 94.96
182 INT164965 Gene_expression of Cle 4 0.58 3.73 0.1 94.92
183 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 94.88
184 INT200193 Gene_expression of Col4a4 8 0.12 5.75 0.43 94.72
185 INT262798 Negative_regulation of Gene_expression of Col4a4 1 0.09 0.9 0 94.72
186 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77 94.72
187 INT112836 Gene_expression of GPX1 7 0.65 3.01 0.45 94.72
188 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 94.64
189 INT6983 Negative_regulation of Positive_regulation of Ca2 18 0.41 4.29 5.03 94.64
190 INT136664 Positive_regulation of Gene_expression of Twist1 49 0.69 25.91 5.41 94.64
191 INT91159 Negative_regulation of Ros1 35 0.44 26.12 5.97 94.60
192 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 94.32
193 INT314365 Binding of epi 1 0.03 4.91 2.7 94.28
194 INT158863 Negative_regulation of Ros1 84 0.35 40.3 10.14 94.28
195 INT262794 Positive_regulation of Negative_regulation of Ecm1 1 0.04 1.07 0.04 94.20
196 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 93.84
197 INT77094 Negative_regulation of Positive_regulation of Serpina3c 1 0.41 0.68 0.53 93.72
198 INT201519 Gene_expression of GPX3 4 0.20 2.31 0.35 93.72
199 INT272309 Negative_regulation of Atr 1 0.24 2.26 0 93.68
200 INT134965 Negative_regulation of Ecm1 7 0.18 7.86 1.7 93.56
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