D:Catatonia

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Disease Term
Synonyms Catatonia Lethal, Catatonia Malignant, Catatonia Organic, Catatonia Schizophreniform, Catatonias, Catatonias Lethal, Catatonias Malignant, Catatonias Organic, CATATONIAS SCHIZOPHRENIFORM, Catatonic, CATATONIC DISORDER ORGANIC
Documents 147
Hot Single Events 39
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Catatonia. They are ordered first by their relevance to Catatonia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT45376 Binding of Cpe and Mme 1 0.07 0.32 2.13 87.68
2 INT21543 Binding of Oprd1 and Cish 2 0.09 0.15 0.78 66.52
3 INT151961 Rbm39 Positive_regulation of Insrr 1 0.17 0.26 0.89 55.80
4 INT129919 IFNA2 Positive_regulation of Gene_expression of SLC6A4 1 0.02 0.38 0.69 25.00
5 INT129921 IL4 Positive_regulation of Gene_expression of SLC6A4 1 0.01 0.38 0.68 25.00
6 INT129920 IFNA2 Regulation of ADO 1 0.00 0.64 0.64 25.00
7 INT346913 Binding of Kars and Positive_regulation of Gene_expression of Ros1 1 0.03 1.25 0.46 5.00
8 INT346914 Binding of Kars and Positive_regulation of Gene_expression of Car2 1 0.05 1.24 0.45 5.00
9 INT346915 Il12a Positive_regulation of Positive_regulation of IFN1@ 1 0.20 1.26 0.34 5.00
10 INT180194 CRH Positive_regulation of CRHR2 1 0.02 0.24 0.27 5.00
11 INT180195 CRH Regulation of CRHR2 1 0.01 0.24 0.27 5.00
12 INT346912 Il6 Positive_regulation of Gene_expression of Il4 1 0.07 0.62 0.24 5.00
13 INT262359 Binding of DISC1 and NDEL1 1 0.04 0.56 0.18 5.00
14 INT262361 Binding of Pde4b and DISC1 1 0.08 0.57 0.18 5.00
15 INT264101 Binding of CYP2D6 and Bche 1 0.07 0.33 0.18 5.00
16 INT349758 Gal Positive_regulation of Galr1 1 0.37 0.44 0.14 5.00
17 INT307627 Binding of BMP1 and CSF2 1 0.01 0.33 0.12 5.00
18 INT264085 CYP2C19 Regulation of CYP3A4 1 0.02 0 0.09 5.00
19 INT264103 Cyp2e1 Regulation of CYP2C9 1 0.04 0 0.09 5.00
20 INT264106 Cyp1a2 Regulation of CYP2D6 1 0.06 0 0.09 5.00
21 INT264104 Cyp1a2 Regulation of CYP2C9 1 0.04 0 0.09 5.00
22 INT264083 CYP2C19 Regulation of CYP2D6 1 0.05 0 0.09 5.00
23 INT264084 CYP2C19 Regulation of CYP2C9 1 0.03 0 0.09 5.00
24 INT264102 Cyp1a2 Regulation of CYP3A4 1 0.03 0 0.09 5.00
25 INT264107 Cyp2e1 Regulation of CYP2D6 1 0.05 0 0.09 5.00
26 INT264105 Cyp2e1 Regulation of CYP3A4 1 0.02 0 0.09 5.00
27 INT342466 Binding of FFAR1 and MAFD1 1 0.03 0.87 0.05 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Catatonia. They are ordered first by their pain relevance and then by number of times they were reported in Catatonia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT29368 Binding of ECT 25 0.41 11.65 5.81 99.92
2 INT202715 Binding of NMS 3 0.27 6.92 0.65 99.80
3 INT32007 Gene_expression of ECT 56 0.62 18.94 11.13 99.80
4 INT202716 Gene_expression of NMS 4 0.49 4.56 0.57 99.80
5 INT159523 Positive_regulation of Gene_expression of ECT 9 0.42 2.1 2.91 99.80
6 INT18543 Negative_regulation of ECT 20 0.37 8.4 5.25 98.40
7 INT105746 Regulation of ECT 22 0.39 7.6 7.47 98.40
8 INT45375 Protein_catabolism of Oprl1 2 0.85 0.56 2.71 98.26
9 INT52180 Binding of Aes 38 0.42 23.16 6.7 97.92
10 INT158070 Localization of Aes 23 0.65 19.93 10.9 97.32
11 INT167964 Gene_expression of Aes 30 0.58 25.41 10.16 97.32
12 INT275875 Negative_regulation of Localization of Aes 2 0.19 3.87 1.8 97.32
13 INT2761 Regulation of Gabrg1 119 0.61 18.8 60.52 95.88
14 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 95.76
15 INT12835 Negative_regulation of Positive_regulation of CRH 6 0.42 3.15 1.76 95.76
16 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 95.28
17 INT5690 Negative_regulation of Binding of Oprd1 36 0.59 8.29 24.52 94.24
18 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78 94.24
19 INT15296 Regulation of Rbm39 45 0.29 10.66 29.27 93.52
20 INT1167 Regulation of Mastl 7 0.53 1.86 3.77 93.52
21 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 93.24
22 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 92.44
23 INT22557 Gene_expression of BMP1 3 0.59 20.18 4.73 92.32
24 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 91.72
25 INT2212 Binding of Abat 89 0.48 18.36 63.99 91.64
26 INT738 Regulation of POMC 459 0.62 111.19 243.74 91.08
27 INT18343 Binding of Fam13a 3 0.13 0.18 3.2 90.32
28 INT40189 Localization of IFNA2 6 0.74 7.7 1.04 89.92
29 INT1163 Negative_regulation of Rbm39 64 0.29 16.8 34.74 89.72
30 INT30313 Binding of Aldh8a1 1 0.04 0.09 1.01 86.48
31 INT7845 Regulation of OPRK1 44 0.62 4.54 30.49 85.76
32 INT30312 Binding of Pdyn 30 0.37 4.2 18.23 85.20
33 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 84.28
34 INT1463 Binding of Pomc 129 0.48 15.89 56.27 83.60
35 INT1425 Gene_expression of Rbm39 143 0.58 51.32 65.44 83.52
36 INT171167 Positive_regulation of Localization of ECT 1 0.38 0.48 0.24 83.48
37 INT32858 Localization of ECT 9 0.66 2.86 1.6 82.44
38 INT16654 Gene_expression of Insrr 138 0.46 58.96 75.68 82.08
39 INT12502 Regulation of Adarb1 50 0.53 7.58 30.01 81.72
40 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 79.76
41 INT768 Positive_regulation of Oprl1 179 0.70 40.05 156.93 69.60
42 INT1160 Positive_regulation of Rbm39 122 0.57 28.19 90.28 68.76
43 INT53798 Gene_expression of Oprk1 14 0.73 1.82 8.24 68.40
44 INT34132 Binding of Oprk1 6 0.48 2.15 4.78 67.68
45 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57 65.60
46 INT5297 Regulation of IFNA2 20 0.56 10.81 5.13 65.32
47 INT40190 Positive_regulation of Regulation of IFNA2 1 0.49 0.07 0.68 65.32
48 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 63.60
49 INT146355 Negative_regulation of Aes 15 0.51 7.83 4.25 60.80
50 INT24525 Regulation of Gal 19 0.60 10.17 9.57 60.64
51 INT349756 Regulation of Galr2 1 0.23 1.94 0.26 59.76
52 INT75932 Binding of Csf2 45 0.37 33.2 8.01 59.32
53 INT1212 Binding of Oprl1 312 0.48 28.6 225.15 57.68
54 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 57.28
55 INT4637 Binding of Adarb1 132 0.41 14.48 67.76 56.16
56 INT18513 Binding of GRIN1 32 0.47 9.44 15.08 52.56
57 INT288087 Regulation of Gene_expression of ECT 1 0.05 0.3 0.7 50.00
58 INT11673 Positive_regulation of ECT 43 0.59 13.93 11.25 48.00
59 INT74203 Positive_regulation of Positive_regulation of Gtpbp4 6 0.50 0.33 4.13 45.36
60 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97 44.76
61 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 43.76
62 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 39.96
63 INT6116 Regulation of Gene_expression of Oprd1 69 0.62 16.43 54 39.96
64 INT7076 Regulation of Serbp1 11 0.45 0.96 8.12 39.96
65 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 39.52
66 INT57502 Positive_regulation of Gene_expression of CRH 30 0.70 23.37 5.7 39.44
67 INT89271 Gene_expression of Serbp1 4 0.52 1.41 4.53 36.72
68 INT275878 Positive_regulation of Gene_expression of Aes 4 0.23 4.54 3.39 36.40
69 INT5610 Positive_regulation of Insr 140 0.69 37.26 86.24 30.16
70 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 25.00
71 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 25.00
72 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64 25.00
73 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 25.00
74 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 25.00
75 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32 25.00
76 INT12111 Negative_regulation of Hbb-ar 11 0.37 6.63 4.22 25.00
77 INT32519 Positive_regulation of Terc 5 0.36 4.41 1.41 25.00
78 INT150422 Positive_regulation of Aes 24 0.43 15.63 8 20.52
79 INT282596 Localization of BMP1 2 0.61 4.04 1.97 7.20
80 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
81 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 5.00
82 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 5.00
83 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
84 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 5.00
85 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 5.00
86 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 5.00
87 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
88 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
89 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
90 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 5.00
91 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
92 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 5.00
93 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 5.00
94 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 5.00
95 INT253 Regulation of PRL 184 0.62 47.27 65.79 5.00
96 INT11937 Localization of Il6 228 0.81 139.83 64.39 5.00
97 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 5.00
98 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 5.00
99 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 5.00
100 INT249 Localization of GHRH 215 0.80 78.02 51.87 5.00
101 INT51163 Gene_expression of Gal 119 0.78 67.48 49.23 5.00
102 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 5.00
103 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06 5.00
104 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
105 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 5.00
106 INT5454 Localization of CRH 124 0.79 79.18 41.53 5.00
107 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 5.00
108 INT56870 Gene_expression of CYP2D6 87 0.78 8.83 37.53 5.00
109 INT104551 Gene_expression of Il18 156 0.76 115.51 36.95 5.00
110 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 5.00
111 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 5.00
112 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 5.00
113 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 5.00
114 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 5.00
115 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 5.00
116 INT92837 Negative_regulation of Gene_expression of Nos2 116 0.59 59.67 31.82 5.00
117 INT10797 Binding of CYP2D6 86 0.48 15.09 31.16 5.00
118 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
119 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 5.00
120 INT47712 Positive_regulation of App 135 0.69 101.38 28.94 5.00
121 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 5.00
122 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45 5.00
123 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26 5.00
124 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 5.00
125 INT15458 Gene_expression of NPY 50 0.76 22.67 23.03 5.00
126 INT45437 Localization of Acot1 84 0.79 17.37 22.18 5.00
127 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61 5.00
128 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98 5.00
129 INT16794 Binding of App 103 0.48 64.87 19.79 5.00
130 INT65502 Regulation of App 77 0.62 52.05 19.44 5.00
131 INT20260 Positive_regulation of Chkb 41 0.64 21.48 18.53 5.00
132 INT14306 Positive_regulation of Gal 36 0.70 21.66 18.51 5.00
133 INT3060 Negative_regulation of Bche 94 0.59 46.75 18.51 5.00
134 INT82531 Positive_regulation of Gene_expression of Gal 41 0.69 28.67 18.04 5.00
135 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04 5.00
136 INT104550 Positive_regulation of Il18 67 0.70 55.14 17.48 5.00
137 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45 5.00
138 INT984 Positive_regulation of Localization of GHRH 58 0.70 12.66 16.51 5.00
139 INT197375 Gene_expression of Car1 84 0.65 16.46 16.45 5.00
140 INT12950 Gene_expression of Cat 85 0.75 35.94 15.76 5.00
141 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73 5.00
142 INT12837 Binding of SIGMAR1 57 0.48 5.31 15.49 5.00
143 INT54284 Negative_regulation of Gene_expression of Oprd1 16 0.42 4.56 14.34 5.00
144 INT20264 Gene_expression of Chkb 29 0.46 13.14 13.65 5.00
145 INT2005 Positive_regulation of Gene_expression of PRL 55 0.70 21.4 13.44 5.00
146 INT141014 Positive_regulation of Gene_expression of Il18 46 0.68 47.63 13.3 5.00
147 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47 5.00
148 INT89248 Positive_regulation of Galr1 14 0.70 6.99 12.3 5.00
149 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09 5.00
150 INT87239 Localization of Il12a 51 0.75 31.95 12.05 5.00
151 INT11429 Gene_expression of ADCY1 26 0.74 5.89 11.93 5.00
152 INT100821 Localization of Ros1 59 0.60 45.26 11.92 5.00
153 INT10798 Positive_regulation of CYP2D6 24 0.56 5.82 11.31 5.00
154 INT62580 Gene_expression of Cyp2e1 31 0.78 15.4 11.08 5.00
155 INT38255 Localization of Chkb 32 0.80 10.98 11.07 5.00
156 INT122682 Gene_expression of Galr2 11 0.63 5.06 10.77 5.00
157 INT3982 Gene_expression of Acot1 53 0.56 7.61 10.46 5.00
158 INT14881 Gene_expression of Car3 49 0.73 14.89 9.94 5.00
159 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 5.00
160 INT140411 Gene_expression of Nqo1 45 0.60 62.35 8.7 5.00
161 INT86792 Gene_expression of Kars 17 0.77 4.24 8.58 5.00
162 INT4487 Positive_regulation of Positive_regulation of PRL 27 0.70 8.06 8.09 5.00
163 INT57922 Gene_expression of CYP2C9 65 0.78 22.24 7.53 5.00
164 INT51164 Gene_expression of Galr1 12 0.78 6.3 7.3 5.00
165 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94 5.00
166 INT20922 Positive_regulation of Localization of CRH 18 0.67 11.12 6.79 5.00
167 INT24527 Negative_regulation of Gal 12 0.59 7.16 6.29 5.00
168 INT122680 Positive_regulation of Gene_expression of Galr2 5 0.56 2.75 6.29 5.00
169 INT2890 Positive_regulation of MB 39 0.70 29.58 6.01 5.00
170 INT143357 Binding of Ros1 48 0.36 27.76 6 5.00
171 INT63042 Binding of Apoe 59 0.48 31.23 5.88 5.00
172 INT74109 Positive_regulation of Sele 26 0.48 22.32 5.84 5.00
173 INT115087 Negative_regulation of Gdnf 10 0.51 5.78 5.73 5.00
174 INT245587 Regulation of Car1 13 0.27 4.68 5.72 5.00
175 INT89247 Transcription of Galr1 7 0.72 3.38 5.61 5.00
176 INT55917 Binding of Sigmar1 26 0.45 12.65 5.58 5.00
177 INT24526 Localization of Gal 13 0.75 3.54 5.5 5.00
178 INT197229 Positive_regulation of Kars 5 0.54 1.89 4.81 5.00
179 INT95538 Localization of CYP2D6 21 0.81 5.69 4.73 5.00
180 INT128353 Negative_regulation of Car3 16 0.37 4.93 4.61 5.00
181 INT1753 Gene_expression of Ache 38 0.78 15.31 4.58 5.00
182 INT65881 Gene_expression of CYP2C19 21 0.76 1.19 4.57 5.00
183 INT138216 Negative_regulation of PER1 13 0.37 9.66 4.55 5.00
184 INT142488 Positive_regulation of Gene_expression of Chkb 7 0.23 4.09 4.54 5.00
185 INT24619 Regulation of Thop1 11 0.44 1.24 4.5 5.00
186 INT34624 Negative_regulation of REM1 22 0.38 9.25 4.22 5.00
187 INT159119 Negative_regulation of Car1 17 0.37 6.6 4.01 5.00
188 INT141015 Regulation of Il18 14 0.59 6.3 3.73 5.00
189 INT20455 Positive_regulation of Bche 15 0.59 7.22 3.7 5.00
190 INT111512 Negative_regulation of Galr1 4 0.59 6.45 3.61 5.00
191 INT8778 Regulation of Ache 17 0.62 3.7 3.57 5.00
192 INT96150 Gene_expression of H2-D1 44 0.27 16.23 3.4 5.00
193 INT117117 Positive_regulation of REM1 12 0.40 10.1 3.33 5.00
194 INT89252 Regulation of Galr1 4 0.62 4.27 3.31 5.00
195 INT307634 Binding of BMP1 1 0.36 3.12 3.26 5.00
196 INT8777 Positive_regulation of Ache 25 0.68 7.77 3.18 5.00
197 INT110755 Negative_regulation of Positive_regulation of Mapk8 15 0.46 9.91 2.98 5.00
198 INT32881 Binding of Igk 5 0.36 1.07 2.95 5.00
199 INT178772 Transcription of App 17 0.70 10.79 2.79 5.00
200 INT22212 Gene_expression of CYP1A1 34 0.76 10.11 2.77 5.00
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