D:Cellulitis

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Disease Term
Synonyms Phlegmon, STREPTOCOCCUS PYOGENES
Documents 221
Hot Single Events 24
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cellulitis. They are ordered first by their relevance to Cellulitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT308170 Binding of thd and Tnfrsf14 1 0.00 1.84 0.46 74.84
2 INT308171 Binding of TNF and thd 1 0.00 1.84 0.45 74.84
3 INT180164 Gast Positive_regulation of Nfasc 1 0.02 1.31 0 50.00
4 INT212527 Binding of PROC and Crp 1 0.00 1.5 0 43.16
5 INT212524 Binding of Crp and Ighm 1 0.02 0.92 0 43.16
6 INT299708 Binding of C3 and PSMC2 1 0.00 0.14 0 41.36
7 INT299698 Binding of CFB and PSMC2 1 0.00 0.14 0 41.24
8 INT212522 Binding of Crp and Cd209a 1 0.00 0.8 0 40.68
9 INT212526 Binding of PROC and Apcs 1 0.01 2.54 0 34.56
10 INT299700 FGL1 Regulation of CFB 1 0.00 0.05 0 23.24
11 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75 22.80
12 INT299709 S100A12 Regulation of CFB 1 0.00 0.05 0 21.20
13 INT299707 ECB2 Regulation of CFB 1 0.00 0 0 19.52
14 INT212528 Binding of MSH6 and Apcs 1 0.00 0.68 0 9.60
15 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54 5.00
16 INT238009 Binding of Cxcr3 and Cxcl9 3 0.40 4.01 1.37 5.00
17 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14 5.00
18 INT308173 Binding of DRG1 and Tnfrsf1b 1 0.01 1.64 1.1 5.00
19 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95 5.00
20 INT355704 Binding of Cia1 and Aia1 1 0.00 1.85 0.77 5.00
21 INT308167 Binding of Eln and Tnfrsf1b 1 0.01 0.94 0.71 5.00
22 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61 5.00
23 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56 5.00
24 INT292873 Binding of Fas and Fasl 5 0.26 15.74 0.49 5.00
25 INT344165 Regulation of Binding of Cxcr3 and Cxcl9 1 0.30 0.47 0.25 5.00
26 INT266646 HMOX2 Regulation of Gene_expression of Hmox1 1 0.00 0.87 0.2 5.00
27 INT299703 ECB2 Negative_regulation of Binding of C5 1 0.00 0.39 0.06 5.00
28 INT246640 GAST Positive_regulation of NFASC 1 0.00 1.26 0.03 5.00
29 INT351952 Sag Positive_regulation of Gene_expression of Tnfrsf1a 1 0.17 1.11 0 5.00
30 INT299705 C5 Positive_regulation of Positive_regulation of C5AR1 1 0.03 0.1 0 5.00
31 INT351951 Negative_regulation of Binding of Fas and Fasl 1 0.29 1.13 0 5.00
32 INT241605 Binding of Tcf15 and SCFV 1 0.07 1 0 5.00
33 INT299701 GAST Positive_regulation of C5AR1 1 0.02 0.41 0 5.00
34 INT212525 MSH6 Positive_regulation of Binding of C1qa 1 0.00 0.38 0 5.00
35 INT299702 Binding of C5AR1 and GAST 1 0.01 0.41 0 5.00
36 INT212523 Binding of C1qa and Apcs 1 0.28 0.38 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cellulitis. They are ordered first by their pain relevance and then by number of times they were reported in Cellulitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT105466 Binding of HM13 1 0.36 1.13 0.09 100.00
2 INT212510 Binding of Apcs 26 0.48 15.2 0.72 99.08
3 INT212516 Positive_regulation of Binding of Apcs 1 0.50 2.22 0 99.08
4 INT138913 Negative_regulation of Gene_expression of Cxcl9 8 0.58 6.22 1.36 97.88
5 INT8477 Negative_regulation of AFP 35 0.58 31.52 3.1 97.66
6 INT104395 Gene_expression of Cxcl9 83 0.76 73.1 19.79 97.60
7 INT2093 Gene_expression of GAST 50 0.78 32.32 7.98 97.28
8 INT70145 Gene_expression of Trav6-3 136 0.76 69.6 18.05 96.56
9 INT74254 Binding of PTPRC 16 0.36 8.37 1.27 96.56
10 INT165687 Positive_regulation of PTCRA 2 0.44 1.93 0.07 95.28
11 INT764 Gene_expression of OLAH 25 0.67 25.58 8.07 94.68
12 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 91.04
13 INT45878 Gene_expression of NEU1 14 0.65 7.28 0.47 90.80
14 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 90.24
15 INT96693 Binding of COL2A1 45 0.46 37.11 2.61 87.52
16 INT303146 Positive_regulation of ETV5 1 0.52 0.15 0.03 86.24
17 INT351935 Binding of seb 1 0.28 1.44 0 84.92
18 INT237051 Gene_expression of Cxcl11 24 0.64 25.74 5.77 84.88
19 INT351925 Binding of Sepsecs 1 0.06 1.43 0 83.84
20 INT323215 Regulation of Binding of ZC3H15 1 0.03 0.99 0 82.88
21 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 81.92
22 INT323217 Binding of ZC3H15 1 0.03 0.98 0 81.88
23 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 81.64
24 INT90826 Localization of NFASC 8 0.17 6.01 1.97 81.64
25 INT125711 Negative_regulation of TSS 6 0.51 3.64 0.12 79.72
26 INT116360 Protein_catabolism of C3 19 0.64 4.4 1 79.36
27 INT35689 Localization of C3 17 0.75 5.3 1.98 79.36
28 INT72565 Localization of IL1RN 45 0.80 23.59 13.17 77.08
29 INT221134 Positive_regulation of NEU1 1 0.19 2.51 0.11 76.92
30 INT80842 Transcription of H1FNT 2 0.07 1.59 0.09 76.48
31 INT174838 Localization of INCENP 80 0.64 19.05 12.89 76.32
32 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 76.00
33 INT303149 Negative_regulation of ETV5 1 0.41 0.08 0 75.36
34 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 75.00
35 INT251561 Binding of Tnfrsf14 3 0.13 6 0.89 74.68
36 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81 73.04
37 INT17268 Localization of PLG 9 0.78 11.71 2.06 72.00
38 INT104387 Positive_regulation of Cxcl9 24 0.67 22.26 7.87 71.92
39 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47 71.84
40 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 69.28
41 INT323218 Gene_expression of ZC3H15 1 0.05 2.59 0.07 65.92
42 INT174839 Localization of BSG 4 0.68 2.91 0.98 65.88
43 INT36301 Negative_regulation of TOP2A 3 0.57 2.66 0 65.04
44 INT303148 Gene_expression of ETV5 1 0.51 0.06 0 64.68
45 INT266626 Binding of Ugt1a2 1 0.00 1.35 0.04 64.16
46 INT266627 Positive_regulation of Ugt1a2 3 0.04 5.54 0.56 63.52
47 INT234509 Regulation of Ptpn22 1 0.01 0.94 0.18 62.92
48 INT46045 Negative_regulation of Gene_expression of C3 5 0.30 3.15 0.45 60.44
49 INT756 Gene_expression of C3 138 0.75 100.6 19.2 59.80
50 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 59.28
51 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66 58.64
52 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 51.96
53 INT7995 Positive_regulation of Lta 28 0.66 14.98 9.8 51.52
54 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 50.00
55 INT90 Localization of Gast 400 0.81 137.67 113 50.00
56 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07 50.00
57 INT30 Gene_expression of Gast 158 0.78 99 41.45 50.00
58 INT91 Positive_regulation of Localization of Gast 96 0.70 23.22 29.36 50.00
59 INT180163 Positive_regulation of Nfasc 49 0.40 31.96 9.41 50.00
60 INT233 Binding of Gast 31 0.42 17.07 5.21 50.00
61 INT180161 Binding of Nfasc 23 0.48 10.92 2.4 50.00
62 INT180160 Positive_regulation of Binding of Gast 2 0.32 2.72 0.12 50.00
63 INT61076 Gene_expression of RHD 9 0.65 3.52 1.39 48.96
64 INT235983 Gene_expression of Sag 3 0.58 6.47 0.16 48.72
65 INT273531 Gene_expression of BRON-J 1 0.31 5.53 0.75 47.68
66 INT206796 Positive_regulation of VAMP7 2 0.56 4.12 0.07 47.60
67 INT29094 Binding of C3 39 0.37 12.65 2.27 41.36
68 INT2774 Binding of Crp 241 0.48 195.89 44.39 40.68
69 INT7872 Positive_regulation of P9Ehs1 74 0.50 18.54 66.16 40.56
70 INT212515 Binding of Cd209a 3 0.05 3.6 0.17 39.88
71 INT120466 Gene_expression of LCT 21 0.78 6 1.75 39.68
72 INT113104 Gene_expression of SCFV 18 0.65 7.13 1.2 39.68
73 INT323214 Regulation of ZC3H15 1 0.02 0.29 0 38.04
74 INT299673 Localization of ECB2 1 0.01 0 0 37.68
75 INT148051 Binding of SCFV 23 0.47 9.86 1.83 37.60
76 INT212508 Gene_expression of Cd209a 2 0.06 3.7 0.2 37.52
77 INT299668 Localization of SCIN 4 0.25 0.43 0 36.40
78 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 35.76
79 INT7994 Gene_expression of Lta 113 0.67 69.81 19.59 35.52
80 INT139743 Binding of Sag 2 0.16 2.33 0.54 33.84
81 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 32.80
82 INT329827 Gene_expression of Ccl6 2 0.34 0.47 0.43 32.24
83 INT221135 Regulation of Binding of NEU1 1 0.17 0.61 0.06 28.44
84 INT14450 Binding of NEU1 7 0.14 5.1 0.5 28.04
85 INT74253 Binding of Magt1 2 0.09 0.49 0.12 25.00
86 INT344155 Gene_expression of Ccl28 1 0.07 0.3 0.31 22.72
87 INT12163 Positive_regulation of OLAH 8 0.68 6.91 1.67 21.12
88 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 20.08
89 INT35271 Negative_regulation of Apcs 12 0.59 8.05 1.36 15.52
90 INT10834 Binding of IL8 65 0.48 41.66 16.53 14.80
91 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 13.28
92 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 7.32
93 INT179688 Negative_regulation of Gene_expression of COPD 13 0.35 16.06 0.97 7.32
94 INT55647 Binding of Nfasc 5 0.35 5.43 0.94 7.12
95 INT85764 Binding of PEBP1 9 0.44 4.52 7.2 5.68
96 INT7114 Positive_regulation of Ltp 1192 0.62 290.76 755.77 5.00
97 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
98 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
99 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
100 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
101 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
102 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
103 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
104 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
105 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 5.00
106 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 5.00
107 INT7628 Gene_expression of Ltp 273 0.77 70.21 147.87 5.00
108 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
109 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
110 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24 5.00
111 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 5.00
112 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
113 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
114 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
115 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
116 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
117 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
118 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
119 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46 5.00
120 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 5.00
121 INT67682 Localization of Bdnf 204 0.81 72.36 88.92 5.00
122 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 5.00
123 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59 5.00
124 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
125 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
126 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 5.00
127 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
128 INT9489 Gene_expression of SFTPA1 112 0.66 55.38 66.45 5.00
129 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26 5.00
130 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 5.00
131 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
132 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 5.00
133 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 5.00
134 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
135 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 5.00
136 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
137 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
138 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
139 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24 5.00
140 INT83953 Gene_expression of Cxcl2 140 0.75 113.07 43.65 5.00
141 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
142 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
143 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
144 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27 5.00
145 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 5.00
146 INT97596 Localization of S100a8 94 0.78 90.69 40.41 5.00
147 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 5.00
148 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 5.00
149 INT168410 Gene_expression of Cxcr3 81 0.75 84.03 37.01 5.00
150 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5 5.00
151 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23 5.00
152 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94 5.00
153 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 5.00
154 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 5.00
155 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 5.00
156 INT166203 Positive_regulation of Cia1 62 0.43 75.94 31.37 5.00
157 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21 5.00
158 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 5.00
159 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
160 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 5.00
161 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 5.00
162 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
163 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
164 INT86789 Gene_expression of P2rx4 46 0.77 30.66 25.68 5.00
165 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 5.00
166 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 5.00
167 INT100026 Gene_expression of Tnfrsf1b 73 0.72 43.26 23.23 5.00
168 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16 5.00
169 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09 5.00
170 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 5.00
171 INT12114 Positive_regulation of Tnfrsf1a 46 0.69 36.26 22.54 5.00
172 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 5.00
173 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03 5.00
174 INT23257 Regulation of CRP 127 0.62 100.05 21.87 5.00
175 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18 5.00
176 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 5.00
177 INT17386 Positive_regulation of Aia1 24 0.38 30.89 20.18 5.00
178 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98 5.00
179 INT182031 Gene_expression of Cia1 38 0.24 46.37 19.64 5.00
180 INT12243 Positive_regulation of PRSS1 91 0.70 52.87 19.48 5.00
181 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93 5.00
182 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 5.00
183 INT151747 Positive_regulation of PSMD2 26 0.68 17.48 17.89 5.00
184 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64 5.00
185 INT50579 Binding of CYP3A4 84 0.48 17.52 17.45 5.00
186 INT12922 Gene_expression of Atp9a 115 0.75 50.95 17.01 5.00
187 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86 5.00
188 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 5.00
189 INT96299 Positive_regulation of Localization of Bdnf 35 0.70 15.67 16.09 5.00
190 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 5.00
191 INT152730 Positive_regulation of S100a8 48 0.68 47.67 15.4 5.00
192 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 5.00
193 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 5.00
194 INT106745 Localization of CRP 65 0.81 66.44 15.21 5.00
195 INT87823 Positive_regulation of Cxcl2 51 0.66 35.47 14.79 5.00
196 INT83950 Gene_expression of Cxcr1 31 0.59 27.76 13.91 5.00
197 INT104954 Negative_regulation of Positive_regulation of Mapk14 29 0.58 17.71 13.31 5.00
198 INT99780 Positive_regulation of Cxcl10 43 0.69 39.67 13.27 5.00
199 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71 5.00
200 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 5.00
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