D:Central Nervous System Disease

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Disease Term
Synonyms Central Nervous System Diseases, CENTRAL NERVOUS SYSTEM DISORDERS, Cns Disease, Cns Diseases, Cns Disorder, Cns Disorders, Disease Of The Central Nervous System, Disorder Of Central Nervous System, Encephalomyeloneuropathy
Documents 383
Hot Single Events 200
Hot Interactions 22

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Central Nervous System Disease. They are ordered first by their relevance to Central Nervous System Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27 100.00
2 INT181453 Gene_expression of Ccl2 Positive_regulation of Gene_expression of Il12rb1 1 0.06 1.87 0.34 100.00
3 INT350701 Mthfd1 Regulation of Gene_expression of Cd4 1 0.03 1.46 0.33 99.68
4 INT181451 Lck Regulation of Mbp 1 0.08 1.43 0.34 97.56
5 INT333765 Positive_regulation of Vdr Regulation of Gene_expression of Ccr6 1 0.21 0.48 0.12 96.68
6 INT333761 Il27 Positive_regulation of Il10 1 0.16 0.58 0.13 96.64
7 INT333758 Hand1 Positive_regulation of Eae1 1 0.05 1.6 0.22 92.80
8 INT333762 Positive_regulation of thd Positive_regulation of Eae1 1 0.00 1.6 0.22 92.80
9 INT333760 thd Positive_regulation of Eae1 1 0.00 1.6 0.22 92.80
10 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87 91.44
11 INT181452 Binding of Ccl19 and Ccl21b 1 0.02 2.22 0.86 91.44
12 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 90.92
13 INT279964 STAT3 Regulation of Transcription of FGG 1 0.22 1.37 0.2 90.64
14 INT183387 Il6 Positive_regulation of Gene_expression of Il10 2 0.19 1.8 0.63 90.32
15 INT237778 Il12b Positive_regulation of Gene_expression of Eae1 1 0.01 1.51 0.39 89.28
16 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04 89.20
17 INT333759 Il6 Positive_regulation of Il27 1 0.09 0.68 0.12 88.88
18 INT181440 Binding of Ccr2 and Eae1 1 0.03 1.3 0.19 87.68
19 INT237774 Il12b Positive_regulation of Eae1 1 0.01 0.58 0.13 86.56
20 INT333764 Il6 Regulation of Gene_expression of Il6ra 1 0.02 0.52 0.12 86.40
21 INT350699 Binding of Casp8 and Stat3 1 0.04 1.81 0.58 84.48
22 INT350716 Binding of CD58 and Casp8 1 0.03 1.81 0.58 84.48
23 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 79.04
24 INT181443 Csf2 Positive_regulation of Cxcl10 1 0.02 1.69 0.39 78.24
25 INT181441 Csf2 Positive_regulation of Cxcl12 1 0.02 1.69 0.39 77.92
26 INT181439 Csf2 Positive_regulation of Ccl19 1 0.06 1.68 0.38 77.48
27 INT350717 MIR219-1 Negative_regulation of Zfp238 1 0.01 0.4 0.16 76.76
28 INT350719 MIR219-1 Negative_regulation of Foxj3 1 0.01 0.4 0.15 76.76
29 INT350713 MIR219-1 Negative_regulation of Pdgfra 1 0.00 0.4 0.15 76.76
30 INT350723 MIR219-1 Negative_regulation of Sox6 1 0.01 0.4 0.15 76.76
31 INT181447 Ccl3 Positive_regulation of Csf2 1 0.06 1.89 0.45 74.32
32 INT181444 Ccl5 Positive_regulation of Csf2 1 0.07 1.88 0.45 73.96
33 INT181448 Eae1 Positive_regulation of Gene_expression of Ccr2 1 0.04 4.98 0.42 73.84
34 INT240537 Binding of Il12a and Ebi3 1 0.08 1.23 0.49 71.84
35 INT237776 Ifna1 Positive_regulation of Eae1 1 0.07 0.66 0.09 70.32
36 INT236833 Binding of CD19 and SDC1 1 0.26 0.54 0.15 69.44
37 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19 67.92
38 INT236834 Binding of CD19 and CSF2 1 0.17 0.53 0.14 67.04
39 INT349636 IL17A Positive_regulation of Gene_expression of IL4 1 0.06 1.28 0.5 65.24
40 INT237777 Il23a Regulation of Localization of Il12a 1 0.19 0.93 0.19 64.80
41 INT346409 Negative_regulation of Binding of mn and Tesc 1 0.00 0.29 0.22 60.56
42 INT346408 Binding of mn and Tesc 1 0.00 0.29 0.22 60.56
43 INT181432 Csf2 Positive_regulation of Ccl5 1 0.03 0.81 0.29 59.12
44 INT181446 Csf2 Positive_regulation of Ccl3 1 0.05 0.81 0.29 59.12
45 INT236835 Binding of CISH and CSF2 1 0.06 1.43 1.25 57.00
46 INT181449 Ccl7 Regulation of Ccl2 1 0.24 0.73 0.25 56.24
47 INT259852 Binding of Il12a and Retnlb 1 0.01 0.59 0.11 51.88
48 INT259851 Binding of Retnlb and Tlr11 1 0.03 0.29 0.05 51.88
49 INT279962 Binding of A1BG and BCL2L1 1 0.13 1.11 0.1 49.20
50 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66 41.28
51 INT181442 Ccl2 Positive_regulation of Localization of Hand2 1 0.26 0.63 0.29 39.72
52 INT181445 Binding of Ccr5 and Hand1 1 0.12 1.01 0.22 38.32
53 INT181438 Il4 Regulation of Gene_expression of Ccl2 1 0.38 0.74 0.35 38.00
54 INT181433 Hand2 Regulation of Gene_expression of Ccl2 1 0.12 0.68 0.32 38.00
55 INT339071 Binding of Mog and Eae1 1 0.00 1.65 0.06 36.08
56 INT288007 Binding of CD28 and CD40 1 0.05 0.51 0.03 34.72
57 INT288008 Binding of CD40 and LRRC23 1 0.02 0.45 0 34.72
58 INT305883 Pcx Negative_regulation of Binding of Tjp1 1 0.04 0.11 0.04 29.56
59 INT305875 Pcx Negative_regulation of Binding of Ocln 1 0.03 0.11 0.04 29.56
60 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32 29.48
61 INT181457 Binding of CCL16 and Hand2 1 0.04 0.92 0.17 29.16
62 INT265346 Binding of Ocln and Tjp1 7 0.05 1.11 0.09 27.84
63 INT333763 Il27 Positive_regulation of Gene_expression of Il10 2 0.22 0.8 0.26 27.04
64 INT206763 Binding of CSF2 and Nqo1 1 0.00 1.7 0.25 25.44
65 INT288163 Binding of gr and Igh-Dex 1 0.03 0.18 0.27 23.28
66 INT308483 Paf Positive_regulation of Gene_expression of Ptafr 1 0.12 1.14 0.78 23.20
67 INT308485 Paf Positive_regulation of Ptafr 1 0.12 1.13 0.77 22.40
68 INT208051 Binding of SNRNP70 and Accn1 1 0.01 1.81 0 12.24
69 INT184125 Il12a Positive_regulation of Stat4 2 0.11 1.04 0.7 9.88
70 INT240539 Il12a Positive_regulation of Stat3 1 0.11 0.75 0.22 9.88
71 INT240538 Il12a Positive_regulation of Phosphorylation of Stat4 1 0.11 0.76 0.22 9.88
72 INT240535 Il12a Positive_regulation of Tyk2 1 0.10 0.75 0.21 9.88
73 INT240536 Il12a Positive_regulation of Jak2 1 0.10 0.74 0.21 9.88
74 INT279961 CSF2 Negative_regulation of TTR 1 0.04 1.07 0.23 9.68
75 INT228333 Binding of IFNA1 and IRF9 2 0.04 0.53 0.09 8.32
76 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27 5.00
77 INT122567 Mog Positive_regulation of Eae1 8 0.31 10.18 4.26 5.00
78 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51 5.00
79 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35 5.00
80 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14 5.00
81 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94 5.00
82 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93 5.00
83 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89 5.00
84 INT339318 Ngf Positive_regulation of Pik3cg 1 0.02 0.69 0.87 5.00
85 INT294908 Pax3 Positive_regulation of Gene_expression of Il1 1 0.03 0.45 0.76 5.00
86 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73 5.00
87 INT294906 Binding of Pax3 and Tac4 1 0.01 1.15 0.71 5.00
88 INT308484 Car2 Positive_regulation of Pla2g4a 1 0.03 1.23 0.65 5.00
89 INT9163 Tnf Regulation of Gene_expression of Glul 1 0.12 1.99 0.62 5.00
90 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61 5.00
91 INT339070 Mog Positive_regulation of Eae1 1 0.01 3.81 0.61 5.00
92 INT339072 Eae1 Positive_regulation of Gene_expression of Nos2 1 0.02 3.76 0.59 5.00
93 INT346412 Binding of Tesc and Sv2a 1 0.02 0.6 0.59 5.00
94 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57 5.00
95 INT232424 VIP Positive_regulation of Localization of PRL 1 0.36 0 0.53 5.00
96 INT236832 CSF2 Regulation of CXCL13 1 0.09 0.34 0.45 5.00
97 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45 5.00
98 INT206538 Trem2 Regulation of Gene_expression of Cd80 1 0.17 1.26 0.44 5.00
99 INT206536 Trem2 Positive_regulation of Gene_expression of Cd80 1 0.30 1.26 0.44 5.00
100 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43 5.00
101 INT346416 Binding of Tesc and Svs1 1 0.00 0.07 0.42 5.00
102 INT294910 Pax3 Regulation of Positive_regulation of Il1 1 0.02 2.03 0.42 5.00
103 INT288162 Igh-Dex Positive_regulation of Gopc 1 0.02 0.63 0.41 5.00
104 INT350693 Mir326 Positive_regulation of Regulation of thd 1 0.00 1.32 0.41 5.00
105 INT350698 Mir326 Regulation of Ets1 1 0.01 1.27 0.4 5.00
106 INT173977 Binding of TNF and Ighg1 1 0.03 0.28 0.39 5.00
107 INT232422 VIP Regulation of Gene_expression of PRL 1 0.40 0 0.37 5.00
108 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37 5.00
109 INT288168 Binding of Jun and Ugcg Negative_regulation of Gene_expression of Mmp13 1 0.01 0.52 0.36 5.00
110 INT288164 Jun Regulation of Gene_expression of Mmp13 1 0.02 0.41 0.35 5.00
111 INT288167 Ugcg Negative_regulation of Gene_expression of Mmp13 1 0.06 0.46 0.35 5.00
112 INT238261 pma Positive_regulation of Prkcg 1 0.01 0.33 0.34 5.00
113 INT232419 ABAT Positive_regulation of Localization of PRL 1 0.09 0 0.33 5.00
114 INT232425 Binding of ABAT and Positive_regulation of PRL 1 0.09 0.15 0.33 5.00
115 INT232420 PRL Positive_regulation of Regulation of ABAT 1 0.09 0 0.33 5.00
116 INT288165 Binding of Jun and Ugcg 1 0.02 0.45 0.32 5.00
117 INT255944 MAPK14 Positive_regulation of Tauph 1 0.00 0.1 0.32 5.00
118 INT255933 Tauph Positive_regulation of Rps6ka5 1 0.00 0.1 0.32 5.00
119 INT255945 MAPK14 Positive_regulation of Rps6ka5 1 0.06 0.1 0.32 5.00
120 INT206208 MRO Negative_regulation of CD24 1 0.02 1.87 0.32 5.00
121 INT255934 Tauph Positive_regulation of Map3k1 1 0.00 0.1 0.32 5.00
122 INT255946 MAPK14 Positive_regulation of Map3k1 1 0.04 0.1 0.32 5.00
123 INT288166 Binding of gr and Ugcg 1 0.07 0.45 0.31 5.00
124 INT313915 Binding of Il12a and Il23a 2 0.16 0.44 0.31 5.00
125 INT9162 Tnf Negative_regulation of Localization of Penk 1 0.34 0.85 0.3 5.00
126 INT9161 Tnf Negative_regulation of Localization of Ifng 1 0.20 0.85 0.3 5.00
127 INT294907 Il1 Positive_regulation of Il6 1 0.06 1.45 0.29 5.00
128 INT258861 Binding of HLA-DOA and HLA-DRB1 2 0.14 1.88 0.28 5.00
129 INT189200 Binding of CA2 and ITPR3 3 0.03 1.9 0.27 5.00
130 INT206535 Binding of Trem2 and Tg(CAG-EGFP)D4Nagy 1 0.03 0.5 0.27 5.00
131 INT181454 Eae7 Regulation of Positive_regulation of Eae1 1 0.06 0.9 0.26 5.00
132 INT238263 pma Positive_regulation of Gene_expression of Cd59 1 0.02 0.57 0.26 5.00
133 INT294905 Binding of Hgf and Pax3 1 0.01 1.54 0.25 5.00
134 INT208037 Binding of Accn1 and Accn3 1 0.15 0.3 0.25 5.00
135 INT294912 Binding of Pax3 and Tacr3 1 0.01 1.54 0.25 5.00
136 INT208036 Binding of Cnga3 and Accn1 1 0.01 0.3 0.25 5.00
137 INT238260 Positive_regulation of pma Negative_regulation of Transcription of C3 1 0.02 0.12 0.23 5.00
138 INT255942 Elk1 Regulation of Binding of ATF2 1 0.07 0.12 0.22 5.00
139 INT255842 CREB1 Regulation of Binding of ATF2 1 0.03 0.12 0.22 5.00
140 INT255837 ATF2 Regulation of Binding of CREB1 1 0.03 0.12 0.22 5.00
141 INT189199 JUN Positive_regulation of KRT16 1 0.31 0.58 0.22 5.00
142 INT255941 ATF2 Regulation of Transcription of Elk1 1 0.07 0.12 0.22 5.00
143 INT255940 Elk1 Regulation of Transcription of CREB1 1 0.03 0.12 0.22 5.00
144 INT206540 mc Positive_regulation of Gene_expression of Cd80 1 0.01 0.62 0.22 5.00
145 INT255835 ATF2 Regulation of Transcription of CREB1 1 0.03 0.12 0.22 5.00
146 INT255839 CREB1 Regulation of Transcription of ATF2 1 0.03 0.12 0.22 5.00
147 INT255937 ATF2 Regulation of Binding of Elk1 1 0.07 0.12 0.22 5.00
148 INT255947 CREB1 Regulation of Transcription of Elk1 1 0.03 0.12 0.22 5.00
149 INT255943 Elk1 Regulation of Binding of CREB1 1 0.03 0.12 0.22 5.00
150 INT255939 Elk1 Regulation of Transcription of ATF2 1 0.07 0.12 0.22 5.00
151 INT206541 mc Regulation of Gene_expression of Cd80 1 0.00 0.62 0.22 5.00
152 INT255938 CREB1 Regulation of Binding of Elk1 1 0.03 0.12 0.22 5.00
153 INT336946 Binding of ITGA4 and VCAM1 1 0.03 2.02 0.21 5.00
154 INT189196 RASGRP1 Positive_regulation of SP1 1 0.05 0.63 0.21 5.00
155 INT206539 Trem2 Positive_regulation of Phosphorylation of Mapk1 1 0.22 0.62 0.2 5.00
156 INT294904 Binding of Pax3 and Slc12a3 1 0.02 1.9 0.2 5.00
157 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19 5.00
158 INT288006 Binding of CD28 and LRRC23 1 0.02 0.54 0.19 5.00
159 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19 5.00
160 INT337697 FGF2 Regulation of VEGFA 1 0.03 0.51 0.18 5.00
161 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18 5.00
162 INT201212 FGF2 Regulation of FGFR1 2 0.09 1.01 0.18 5.00
163 INT337698 VEGFA Regulation of FGFR1 1 0.09 0.51 0.18 5.00
164 INT350603 MIR25 Regulation of TGFB1 1 0.01 0.42 0.18 5.00
165 INT351088 Negative_regulation of ERBB2 Positive_regulation of FOXO3 1 0.17 0.66 0.18 5.00
166 INT350702 Rc3h1 Positive_regulation of Protein_catabolism of Icos 1 0.35 1.56 0.18 5.00
167 INT238264 pma Negative_regulation of Gene_expression of Cr1l 1 0.02 0.26 0.16 5.00
168 INT238222 pma Positive_regulation of Prkcg Negative_regulation of Gene_expression of Cr1l 1 0.01 0.26 0.16 5.00
169 INT238262 Prkcg Negative_regulation of Gene_expression of Cr1l 1 0.12 0.26 0.16 5.00
170 INT346414 Thy1 Positive_regulation of Binding of Tesc 1 0.00 0.16 0.15 5.00
171 INT206212 UTS2R Positive_regulation of CD24 1 0.09 0.71 0.15 5.00
172 INT346411 Binding of Caprin1 and Mtus1 1 0.00 0.17 0.14 5.00
173 INT350711 Ifnb1 Negative_regulation of Gene_expression of DICER1 1 0.03 0.15 0.14 5.00
174 INT346410 Binding of Caprin1 and Tesc 1 0.00 0.17 0.14 5.00
175 INT206209 MRO Negative_regulation of Transcription of CD24 1 0.02 0.76 0.14 5.00
176 INT238258 C7 Negative_regulation of C6 1 0.09 0.24 0.13 5.00
177 INT238259 Regulation of C7 Negative_regulation of C6 1 0.06 0.24 0.13 5.00
178 INT284309 Tlr4 Positive_regulation of Mir155 3 0.18 0.51 0.11 5.00
179 INT350694 Uts2r Negative_regulation of Negative_regulation of Rc3h1 1 0.05 0.79 0.1 5.00
180 INT350695 Mir101a Positive_regulation of Protein_catabolism of Icos 1 0.05 0.8 0.1 5.00
181 INT189195 Binding of C4A and C4B 1 0.14 2.45 0.09 5.00
182 INT228350 IFNA1 Positive_regulation of Transcription of Irf2 1 0.04 0.27 0.09 5.00
183 INT297589 Binding of HAT1 and Il10 1 0.00 1.14 0.08 5.00
184 INT350700 Binding of Bcl6 and thd 1 0.00 0.21 0.08 5.00
185 INT174133 Binding of Igfals and Sod1 3 0.19 3 0.08 5.00
186 INT350721 Binding of Hand1 and TBX21 1 0.13 0.22 0.08 5.00
187 INT350692 Binding of Bcl6 and Hand1 1 0.02 0.16 0.08 5.00
188 INT350720 Binding of Bcl6 and TBX21 1 0.07 0.22 0.08 5.00
189 INT297559 Binding of IL6 and HAT1 1 0.00 1.13 0.08 5.00
190 INT350708 Foxp3 Regulation of Socs1 1 0.08 0.21 0.07 5.00
191 INT275661 Mir599 Regulation of MIR96 1 0.01 0.53 0.07 5.00
192 INT275653 MIR18B Regulation of MIR96 1 0.06 0.53 0.07 5.00
193 INT275651 MIR493 Regulation of MIR96 1 0.06 0.53 0.07 5.00
194 INT275650 MIR193A Regulation of MIR96 1 0.13 0.48 0.07 5.00
195 INT346415 Binding of Mns1 and Sv2a 1 0.03 0.14 0.07 5.00
196 INT297562 TNF Positive_regulation of IFNA1 1 0.00 0.62 0.06 5.00
197 INT334683 Eae1 Regulation of Cnp 1 0.03 0.5 0.06 5.00
198 INT334687 Eae1 Regulation of Gene_expression of Cnp 1 0.06 0.5 0.06 5.00
199 INT334686 Olig1 Regulation of Plp1 1 0.17 0.55 0.06 5.00
200 INT334689 Olig1 Regulation of Gene_expression of Cnp 1 0.20 0.55 0.06 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Central Nervous System Disease. They are ordered first by their pain relevance and then by number of times they were reported in Central Nervous System Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT181355 Regulation of Gene_expression of Ccl2 12 0.44 10.37 3.21 100.00
2 INT333746 Negative_regulation of Gene_expression of Ccr6 1 0.46 3.76 0.94 99.92
3 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 99.84
4 INT140170 Binding of Nqo1 24 0.38 36.16 6.79 99.84
5 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 99.84
6 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 99.84
7 INT214464 Regulation of Gene_expression of Cd44 3 0.34 2.95 0.17 99.84
8 INT288159 Regulation of Gene_expression of Itgal 1 0.15 1.16 0.14 99.84
9 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41 99.80
10 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85 99.80
11 INT81243 Regulation of Eno1 2 0.06 2.18 0.94 99.78
12 INT181344 Gene_expression of Ccr6 28 0.61 24.34 9.78 99.68
13 INT118343 Positive_regulation of Eae1 121 0.39 136.06 34.87 99.68
14 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01 99.68
15 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15 99.68
16 INT181405 Gene_expression of Ccl20 26 0.65 23.02 9.46 99.68
17 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 99.68
18 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21 99.68
19 INT181383 Transcription of Ccl22 1 0.44 1 0.76 99.68
20 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54 99.68
21 INT202935 Gene_expression of SERPINF1 12 0.50 7.53 1.54 99.68
22 INT145888 Negative_regulation of Mthfd1 27 0.41 8.98 5.4 99.68
23 INT181409 Positive_regulation of Ccl20 8 0.54 3.41 1.81 99.68
24 INT181384 Positive_regulation of Ccr6 3 0.55 2.53 1.24 99.68
25 INT181343 Negative_regulation of Gene_expression of Il12rb1 1 0.05 1.8 0.31 99.60
26 INT181368 Gene_expression of Ccl21b 1 0.03 3.48 2.01 99.58
27 INT109910 Gene_expression of CCL16 104 0.74 76.1 43.97 99.58
28 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 99.52
29 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 99.52
30 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 99.52
31 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98 99.52
32 INT192073 Positive_regulation of Gene_expression of ADA 8 0.47 10.35 1.12 99.52
33 INT140413 Gene_expression of AQP4 113 0.78 139.25 25.53 99.42
34 INT181359 Transcription of Ccr1 4 0.53 1.66 0.8 99.42
35 INT17747 Regulation of Cd4 14 0.41 10.02 2.12 99.42
36 INT181394 Gene_expression of Il12rb1 2 0.25 2.01 0.64 99.40
37 INT346398 Binding of Tesc 1 0.02 1.88 3.14 99.36
38 INT48411 Gene_expression of Cd44 35 0.77 27.05 4.29 99.32
39 INT259847 Gene_expression of Tlr13 1 0.72 10.37 3.04 99.28
40 INT240527 Gene_expression of Il27 4 0.26 5.05 1.56 99.24
41 INT259832 Positive_regulation of Slc12a3 3 0.23 2.07 0.46 99.20
42 INT153271 Localization of Ccl3 7 0.81 11.29 7.14 99.14
43 INT181379 Localization of Ccl22 5 0.61 5.11 1.49 99.14
44 INT181348 Localization of Ccl5 24 0.65 19.55 6.8 99.14
45 INT140224 Localization of Ccl2 32 0.72 26.91 9.39 99.14
46 INT173505 Localization of Hand2 63 0.57 45.32 13.66 99.14
47 INT20378 Localization of Hand1 53 0.71 41.96 13.31 99.14
48 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.12
49 INT259834 Positive_regulation of Gene_expression of Tlr13 1 0.47 3.11 0.98 99.12
50 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 99.12
51 INT166966 Gene_expression of Ccr7 14 0.48 7.36 4.2 99.08
52 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 99.08
53 INT49405 Gene_expression of Itgal 40 0.75 27.3 4.8 98.96
54 INT96270 Gene_expression of D9Mit120 1 0.03 1.99 0.65 98.96
55 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18 98.96
56 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 98.90
57 INT96271 Positive_regulation of Gene_expression of Mcpt1 30 0.53 21.34 11.06 98.90
58 INT228404 Gene_expression of Slc12a3 6 0.35 7.18 1 98.88
59 INT334681 Positive_regulation of Olig1 1 0.46 0.96 0.4 98.88
60 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 98.80
61 INT160563 Localization of Il17a 34 0.74 26.53 10.24 98.80
62 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 98.80
63 INT425 Localization of PRL 455 0.81 189.64 144.8 98.76
64 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 98.72
65 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 98.60
66 INT96269 Positive_regulation of Mcpt1 71 0.61 52.38 20.4 98.60
67 INT237762 Regulation of Positive_regulation of Eae1 3 0.03 3.15 0.96 98.56
68 INT182240 Gene_expression of CXCL13 25 0.59 22.77 11.96 98.52
69 INT107074 Gene_expression of C5 14 0.75 9.87 3.64 98.44
70 INT74290 Gene_expression of C3ar1 20 0.39 16.33 7.16 98.44
71 INT232180 Positive_regulation of Slc43a1 2 0.09 1.79 0.98 98.42
72 INT181396 Transcription of Csf2 15 0.48 6.38 2.17 98.36
73 INT174432 Transcription of Cxcr3 8 0.68 15.73 7.32 98.36
74 INT181397 Transcription of Ccr5 2 0.62 1.33 0.46 98.36
75 INT181358 Transcription of Ccr7 1 0.43 1.33 0.43 98.36
76 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58 98.24
77 INT259833 Gene_expression of Tlr12 1 0.53 1.47 0.59 98.24
78 INT129279 Negative_regulation of D17Mit246 1 0.35 2.72 0.97 98.24
79 INT167679 Gene_expression of Ccr5 74 0.75 59.03 18.16 98.18
80 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81 98.18
81 INT89294 Gene_expression of Ccr3 53 0.68 43.9 12.62 98.18
82 INT181375 Gene_expression of Ccl22 6 0.49 5.54 2.36 98.08
83 INT181414 Gene_expression of Ccl19 12 0.74 9.8 4.11 98.04
84 INT165058 Negative_regulation of MID1 14 0.37 10.82 4.67 97.98
85 INT252 Localization of GH1 529 0.80 227.4 122.05 97.98
86 INT117043 Gene_expression of Itga1 4 0.37 3.3 0.77 97.96
87 INT7561 Positive_regulation of gr 70 0.57 31.92 20.22 97.76
88 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 97.68
89 INT244768 Gene_expression of Olig1 2 0.77 3.56 1.19 97.68
90 INT186284 Binding of Il27 3 0.16 1.85 0.78 97.68
91 INT288158 Negative_regulation of Gene_expression of Cd44 5 0.30 5.73 0.59 97.56
92 INT118870 Positive_regulation of STAT1 36 0.67 26.18 5.46 97.56
93 INT300370 Positive_regulation of MIR34A 8 0.45 8.13 1.44 97.48
94 INT96151 Negative_regulation of Gene_expression of Cd40 20 0.58 6.06 2.58 97.44
95 INT54587 Positive_regulation of Hras1 12 0.27 5.54 1.3 97.16
96 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 97.00
97 INT32945 Binding of IFNB1 3 0.48 2.17 0.58 96.96
98 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7 96.88
99 INT181350 Gene_expression of Ccl7 12 0.61 14.25 4.87 96.84
100 INT181395 Gene_expression of Ccl8 11 0.67 13.88 4.56 96.84
101 INT157572 Gene_expression of Ccl12 10 0.70 10.52 3.09 96.84
102 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 96.80
103 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83 96.80
104 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 96.76
105 INT262060 Positive_regulation of Vdr 8 0.58 2.84 0.67 96.68
106 INT333738 Regulation of Positive_regulation of Vdr 1 0.38 0.48 0.12 96.68
107 INT87470 Gene_expression of SDC1 27 0.78 24.86 5.81 96.48
108 INT101010 Positive_regulation of Positive_regulation of B4GALNT1 5 0.06 4.49 1.83 96.40
109 INT5045 Regulation of VIP 26 0.62 7.15 11.61 96.28
110 INT31875 Regulation of CCBE1 8 0.04 4.18 2.64 96.28
111 INT43898 Regulation of Gene_expression of CCBE1 1 0.01 0.17 0.5 96.28
112 INT165057 Binding of MID1 7 0.32 4.13 3.12 96.24
113 INT181340 Negative_regulation of Negative_regulation of Ccr1 1 0.28 0.67 0.18 96.12
114 INT220171 Regulation of Gene_expression of Ccr6 2 0.49 2.52 0.72 96.08
115 INT181408 Localization of Tnpo1 2 0.13 2.4 1.16 96.08
116 INT60700 Gene_expression of Itgax 93 0.71 51.89 6.57 96.08
117 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 96.04
118 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 96.04
119 INT79062 Gene_expression of B4GALNT1 42 0.14 18.89 6.98 96.04
120 INT284274 Positive_regulation of Mir155 10 0.50 7.68 2.67 96.00
121 INT19491 Gene_expression of CD19 44 0.75 28.8 3.47 96.00
122 INT181402 Negative_regulation of Ccr1 8 0.42 7 2.2 95.92
123 INT112970 Regulation of Ccr1 8 0.29 7.77 1.93 95.92
124 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45 95.88
125 INT9695 Negative_regulation of Csf2 41 0.57 31.65 6.28 95.88
126 INT334676 Regulation of Negative_regulation of Olig1 1 0.27 2.39 0.55 95.84
127 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 95.84
128 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08 95.80
129 INT102548 Negative_regulation of Ccr2 14 0.59 19.84 7.22 95.80
130 INT181373 Negative_regulation of Gene_expression of Ccr2 5 0.59 5.92 1.44 95.80
131 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 95.76
132 INT2732 Gene_expression of VIP 74 0.78 24.57 33.72 95.72
133 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 95.68
134 INT264641 Binding of AES 25 0.42 18.56 6.98 95.60
135 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77 95.56
136 INT22949 Gene_expression of CCBE1 8 0.19 4.27 3.25 95.56
137 INT10885 Negative_regulation of C3 9 0.38 11.86 1.35 95.52
138 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 95.52
139 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 95.48
140 INT74449 Positive_regulation of B4GALNT1 53 0.30 34.49 14.96 95.48
141 INT334680 Negative_regulation of Olig1 1 0.43 9.5 2.32 95.40
142 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68 95.24
143 INT173647 Positive_regulation of Gene_expression of MAPK14 15 0.39 7.54 2.05 95.24
144 INT154094 Negative_regulation of Eae1 25 0.18 30.42 7.89 95.16
145 INT181022 Binding of Ccr1 15 0.37 10.69 5.37 95.12
146 INT259848 Regulation of Slc12a3 2 0.12 2.1 0.3 95.04
147 INT144083 Positive_regulation of Gene_expression of Ccl3 10 0.50 8.16 3.81 95.04
148 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 94.88
149 INT173537 Binding of CCL16 18 0.40 13.02 7.36 94.88
150 INT1578 Negative_regulation of Localization of PRL 52 0.59 20.62 17.18 94.88
151 INT181413 Regulation of Lck 2 0.36 2.54 0.33 94.60
152 INT19492 Regulation of B2M 16 0.60 10.97 2.55 94.60
153 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 94.48
154 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 94.48
155 INT173639 Positive_regulation of INCENP 40 0.14 20.97 6.7 94.40
156 INT236845 Gene_expression of PTPRCAP 1 0.04 0.62 0.17 94.28
157 INT115091 Localization of thd 2 0.04 2.38 0.97 94.16
158 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 94.08
159 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51 94.08
160 INT177759 Negative_regulation of IFN1@ 51 0.57 31.81 7.76 94.08
161 INT334674 Regulation of Olig1 1 0.27 2.13 0.82 94.04
162 INT334678 Localization of Olig1 1 0.70 1.23 0.55 94.04
163 INT124655 Negative_regulation of PECAM1 13 0.23 10.32 3.78 93.96
164 INT174426 Gene_expression of Ccr8 11 0.49 11.68 3.65 93.92
165 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 93.92
166 INT96272 Regulation of D9Mit120 1 0.02 2.07 0.73 93.84
167 INT129358 Gene_expression of ELOVL1 23 0.66 29.39 2.83 93.84
168 INT259838 Positive_regulation of Tlr13 1 0.43 1.58 0.4 93.76
169 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14 93.64
170 INT153268 Positive_regulation of Ccr5 25 0.66 19 7.02 93.44
171 INT137767 Gene_expression of Eae1 74 0.34 89.32 20.48 93.36
172 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62 93.36
173 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67 93.36
174 INT305870 Localization of Pcx 1 0.32 1.1 0.16 93.36
175 INT160941 Negative_regulation of LASP1 2 0.29 1.57 0.59 93.24
176 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51 93.12
177 INT174417 Gene_expression of Ccr4 5 0.42 3.77 2.49 93.04
178 INT109010 Negative_regulation of Ifnb1 1 0.12 2.47 1.56 93.00
179 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 92.96
180 INT277788 Negative_regulation of Gene_expression of Itgal 4 0.29 2.05 0.39 92.68
181 INT168410 Gene_expression of Cxcr3 81 0.75 84.03 37.01 92.64
182 INT138911 Negative_regulation of Cxcl9 5 0.42 3.31 1.35 92.64
183 INT181406 Binding of Ccr5 16 0.45 17 5.78 92.56
184 INT181341 Binding of Ccr2 8 0.32 6.47 1.77 92.56
185 INT181380 Binding of Ccr3 2 0.24 1.12 0.37 92.56
186 INT181346 Binding of Ccr4 1 0.17 1.05 0.27 92.56
187 INT181374 Binding of Ccr6 2 0.29 1.51 0.56 92.56
188 INT181354 Binding of Ccr7 2 0.23 1.94 1.01 92.56
189 INT181411 Binding of Ccr8 1 0.24 0.99 0.27 92.56
190 INT174422 Binding of Cxcr3 24 0.47 26.09 8.34 92.56
191 INT154455 Gene_expression of dds 4 0.58 3.84 0.46 92.44
192 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 92.36
193 INT79260 Negative_regulation of Itgal 2 0.37 2.11 0.33 92.28
194 INT181345 Positive_regulation of Ccl12 6 0.61 9.68 2.07 92.24
195 INT181019 Positive_regulation of Ccl7 5 0.42 5.52 1.27 92.24
196 INT181352 Positive_regulation of Ccl8 3 0.53 5.44 1.23 92.24
197 INT62031 Gene_expression of Cd19 27 0.65 10.39 0.93 92.24
198 INT102839 Gene_expression of Pdc 15 0.52 6.3 1.87 92.08
199 INT187096 Negative_regulation of Cd44 6 0.30 5.92 0.7 91.88
200 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 91.80
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