D:Central Nervous System Lupus Vasculitis

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pChart

Disease Term
Synonyms Central Nervous System Lupus, Central Nervous System Systemic Lupus Erythematosis, Lupus Meningoencephalitides, Lupus Meningoencephalitis, Meningoencephalitides Lupus, Meningoencephalitis Lupus, Neuropsychiatric Systemic Lupus Erythematosus, SYSTEMIC LUPUS ERYTHEMATOSIS CENTRAL NERVOUS SYSTEM
Documents 22
Hot Single Events 3
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Central Nervous System Lupus Vasculitis. They are ordered first by their relevance to Central Nervous System Lupus Vasculitis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
2 INT254287 Binding of TNFSF13B and TNFRSF13B 1 0.01 1.33 0.3 5.00
3 INT254288 Binding of ZNF623 and TNFSF13B 1 0.00 1.33 0.3 5.00
4 INT254286 Binding of TNFSF13B and TNFRSF13C 1 0.07 1.26 0.08 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Central Nervous System Lupus Vasculitis. They are ordered first by their pain relevance and then by number of times they were reported in Central Nervous System Lupus Vasculitis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 98.26
2 INT23465 Gene_expression of S100b 31 0.76 15.09 6.2 97.08
3 INT128750 Binding of Ddx41 13 0.34 4.35 0.57 87.80
4 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 75.00
5 INT20982 Positive_regulation of SERPINB1 7 0.28 7.27 1.61 75.00
6 INT125766 Regulation of S100b 7 0.38 4.31 1.33 75.00
7 INT147009 Regulation of Gene_expression of S100b 2 0.07 0.34 0.1 75.00
8 INT184742 Binding of MAP2 6 0.37 3.29 0.06 74.32
9 INT19341 Gene_expression of IGH@ 4 0.59 6.4 0.7 72.04
10 INT254298 Protein_catabolism of AES 6 0.55 9.79 1.43 43.08
11 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
12 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
13 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
14 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
15 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 5.00
16 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
17 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
18 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
19 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 5.00
20 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
21 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
22 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
23 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 5.00
24 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 5.00
25 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 5.00
26 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
27 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 5.00
28 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
29 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 5.00
30 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 5.00
31 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 5.00
32 INT44602 Gene_expression of TNFSF13B 37 0.75 30.98 9.96 5.00
33 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 5.00
34 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 5.00
35 INT25381 Localization of Csf2 62 0.76 47.48 9.03 5.00
36 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1 5.00
37 INT1127 Negative_regulation of IGHG3 32 0.28 21.1 7.37 5.00
38 INT93003 Binding of CD40 28 0.47 20.25 7.13 5.00
39 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 5.00
40 INT46721 Regulation of Csf2 26 0.45 20.4 6.18 5.00
41 INT201130 Localization of AES 31 0.63 25.45 5.12 5.00
42 INT106972 Gene_expression of MAP2 36 0.75 9.72 3.87 5.00
43 INT108761 Localization of Alms1 24 0.70 13.92 3.74 5.00
44 INT125237 Negative_regulation of Gene_expression of CD40LG 16 0.54 9.9 3.27 5.00
45 INT135639 Gene_expression of Ina 3 0.76 9.58 2.89 5.00
46 INT38673 Negative_regulation of KRT20 38 0.42 22.49 2.77 5.00
47 INT29094 Binding of C3 39 0.37 12.65 2.27 5.00
48 INT16385 Regulation of C3 20 0.41 9.98 1.92 5.00
49 INT129231 Gene_expression of Ddx41 29 0.63 9.73 1.52 5.00
50 INT22434 Gene_expression of Ads1 10 0.75 9.16 1.4 5.00
51 INT29898 Negative_regulation of C6orf25 16 0.29 9.58 1.33 5.00
52 INT119669 Gene_expression of Igh-VS107 9 0.49 3.95 1.31 5.00
53 INT254308 Negative_regulation of TNFSF13B 10 0.42 5.12 1.25 5.00
54 INT150219 Localization of TNFSF13B 2 0.47 5.91 1.15 5.00
55 INT231794 Binding of Fcr 4 0.07 3.08 1.07 5.00
56 INT30886 Positive_regulation of Ina 5 0.62 1.35 0.96 5.00
57 INT135635 Binding of Ina 2 0.41 8.28 0.88 5.00
58 INT150217 Binding of TNFSF13B 2 0.30 4.41 0.84 5.00
59 INT219247 Positive_regulation of Ddx41 9 0.36 6.7 0.84 5.00
60 INT184743 Localization of BTG3 4 0.68 3.6 0.78 5.00
61 INT215469 Positive_regulation of TNFSF13B 9 0.43 7.14 0.7 5.00
62 INT65235 Negative_regulation of Ads1 4 0.57 0.87 0.49 5.00
63 INT315712 Positive_regulation of Gene_expression of Ddx41 3 0.31 2.24 0.46 5.00
64 INT254289 Regulation of Ads1 2 0.26 1.14 0.38 5.00
65 INT179967 Regulation of Ina 2 0.38 0.32 0.28 5.00
66 INT254302 Gene_expression of ICOS 1 0.01 4.03 0.2 5.00
67 INT315717 Positive_regulation of Gene_expression of Ina 1 0.59 1.67 0.17 5.00
68 INT315715 Negative_regulation of Binding of Ina 1 0.42 1.68 0.16 5.00
69 INT315714 Phosphorylation of Ddx41 1 0.12 0.97 0.14 5.00
70 INT187059 Positive_regulation of Ads1 3 0.67 2.07 0.12 5.00
71 INT315713 Negative_regulation of Binding of Ddx41 1 0.06 1 0.1 5.00
72 INT254306 Localization of TNFRSF13B 1 0.03 1.26 0.08 5.00
73 INT315716 Localization of Ina 1 0.68 1.01 0.08 5.00
74 INT254301 Regulation of TNFSF13B 1 0.28 1.09 0.07 5.00
75 INT254307 Localization of TNFRSF13C 1 0.14 1.05 0.07 5.00
76 INT254299 Protein_catabolism of TNFSF13B 1 0.41 1.02 0.05 5.00
77 INT254303 Binding of TNFRSF13B 1 0.02 1.07 0.04 5.00
78 INT254304 Negative_regulation of Binding of TNFSF13B 1 0.37 0.85 0.04 5.00
79 INT315719 Regulation of Localization of Ina 1 0.23 0.51 0.04 5.00
80 INT315718 Positive_regulation of Positive_regulation of Ina 1 0.59 0.37 0.03 5.00
81 INT184744 Regulation of Gene_expression of MAP2 1 0.45 0.92 0 5.00
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