D:Central Sleep Apnea

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pChart

Disease Term
Synonyms Alveolar Hypoventilation Central, ALVEOLAR HYPOVENTILATIONS CENTRAL, Apnea Central, Apnea Central Sleep, Apnea Sleep Central, Apneas Central, Apneas Central Sleep, Breathing Central Sleep Disordered, Breathings Central Sleep Disordered, Central Alveolar Hypoventilation, Central Apnea
Documents 77
Hot Single Events 12
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Central Sleep Apnea. They are ordered first by their relevance to Central Sleep Apnea and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT292928 Olr717 Regulation of Grip2 1 0.00 0 0.37 5.00
2 INT239087 Binding of SST and Negative_regulation of Localization of GH1 1 0.19 0.36 0.24 5.00
3 INT267684 Binding of INS and ARID1B 3 0.10 6.08 0.09 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Central Sleep Apnea. They are ordered first by their pain relevance and then by number of times they were reported in Central Sleep Apnea. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT176618 Gene_expression of HEY1 29 0.59 36 4.37 100.00
2 INT4395 Positive_regulation of CSH1 20 0.50 6.27 1.52 100.00
3 INT177643 Binding of CENPJ 12 0.36 8.59 0.22 99.42
4 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54 99.28
5 INT126685 Gene_expression of Rem1 30 0.65 11.21 3.61 98.16
6 INT115 Negative_regulation of Maoa 65 0.59 16.27 38.66 97.44
7 INT273638 Negative_regulation of TRIP10 1 0.07 1.85 0 96.32
8 INT7716 Positive_regulation of Positive_regulation of Adra2a 9 0.68 0.8 4.69 88.36
9 INT7717 Positive_regulation of Adra2a 62 0.70 17.68 27.32 87.84
10 INT3108 Binding of Tst 11 0.32 13.37 0.77 83.72
11 INT201652 Positive_regulation of Tnfsf10 26 0.68 26.79 2.14 83.72
12 INT61784 Positive_regulation of CENPJ 27 0.51 11.46 2.28 80.32
13 INT45219 Positive_regulation of Phmr 3 0.30 0.48 0.81 77.12
14 INT2101 Binding of Pdia4 2 0.31 0.29 0.4 69.36
15 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 59.36
16 INT812 Localization of INS 1026 0.81 515.6 145.31 41.76
17 INT9199 Positive_regulation of CEBPZ 111 0.67 30.99 28.45 36.00
18 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 33.44
19 INT83734 Negative_regulation of RLS 24 0.50 35.75 5.66 31.64
20 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 28.40
21 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 27.60
22 INT267698 Gene_expression of ARID1B 18 0.63 20.47 0.47 21.96
23 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 15.24
24 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 14.96
25 INT443 Localization of POMC 1020 0.81 284.52 443.17 5.00
26 INT16260 Gene_expression of Bdnf 671 0.78 283.44 339.1 5.00
27 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
28 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 5.00
29 INT1352 Localization of Acot1 728 0.80 73.01 296.01 5.00
30 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 5.00
31 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
32 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 5.00
33 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
34 INT695 Binding of POMC 304 0.48 56.66 126.85 5.00
35 INT252 Localization of GH1 529 0.80 227.4 122.05 5.00
36 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 5.00
37 INT16253 Positive_regulation of Gene_expression of Bdnf 196 0.70 92.67 113.01 5.00
38 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
39 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 5.00
40 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 5.00
41 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41 5.00
42 INT253 Regulation of PRL 184 0.62 47.27 65.79 5.00
43 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9 5.00
44 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
45 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 5.00
46 INT47680 Regulation of Gene_expression of Bdnf 92 0.62 41.61 53.24 5.00
47 INT249 Localization of GHRH 215 0.80 78.02 51.87 5.00
48 INT5118 Regulation of SST 97 0.62 34.35 51.74 5.00
49 INT654 Localization of REN 250 0.81 75.12 47.86 5.00
50 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33 5.00
51 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 5.00
52 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 5.00
53 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
54 INT3188 Regulation of Localization of Acot1 84 0.59 8.94 38.56 5.00
55 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 5.00
56 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 5.00
57 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 5.00
58 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92 5.00
59 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
60 INT691 Binding of SST 67 0.48 24.66 32.67 5.00
61 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 5.00
62 INT49110 Regulation of Grip2 46 0.61 13.57 30.87 5.00
63 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82 5.00
64 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36 5.00
65 INT7664 Negative_regulation of Grip2 68 0.49 10.11 29.93 5.00
66 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
67 INT56524 Gene_expression of Grip2 67 0.74 14.77 26.23 5.00
68 INT7394 Positive_regulation of Localization of GNRH1 67 0.69 7.22 25.29 5.00
69 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 5.00
70 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 5.00
71 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 5.00
72 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 5.00
73 INT104395 Gene_expression of Cxcl9 83 0.76 73.1 19.79 5.00
74 INT75742 Binding of RLS 86 0.42 95.27 19.04 5.00
75 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 5.00
76 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 5.00
77 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78 5.00
78 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15 5.00
79 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 5.00
80 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 5.00
81 INT987 Localization of TRH 37 0.78 10.53 11.1 5.00
82 INT10009 Positive_regulation of TRH 31 0.67 8.94 11.03 5.00
83 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29 5.00
84 INT51259 Gene_expression of Zbtb38 17 0.05 5.63 9.51 5.00
85 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 5.00
86 INT34777 Localization of IGF1 82 0.80 42.68 8.62 5.00
87 INT156827 Localization of MRI1 25 0.65 16.06 8.33 5.00
88 INT48725 Gene_expression of IGFBP3 128 0.78 78.83 8.19 5.00
89 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8 5.00
90 INT16395 Gene_expression of CEBPZ 30 0.57 11.02 6.66 5.00
91 INT9683 Binding of GH1 57 0.47 21.14 5.99 5.00
92 INT53196 Binding of Cd4 44 0.47 27.28 5.85 5.00
93 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71 5.00
94 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 5.00
95 INT4378 Regulation of Gene_expression of GH1 26 0.47 10.2 4.61 5.00
96 INT91463 Positive_regulation of NFKB2 19 0.40 17.7 4.6 5.00
97 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68 5.00
98 INT49702 Negative_regulation of Negative_regulation of Grip2 9 0.43 1.77 3.54 5.00
99 INT48726 Gene_expression of IGFBP1 27 0.67 9.45 3.36 5.00
100 INT180250 Positive_regulation of GLUL 23 0.29 7.57 3.23 5.00
101 INT36286 Binding of Cd3e 33 0.36 10.11 3.21 5.00
102 INT94925 Regulation of Gene_expression of Grip2 7 0.55 4.23 3.18 5.00
103 INT81955 Positive_regulation of SPTLC1 12 0.70 10.25 3.12 5.00
104 INT4488 Gene_expression of TSHB 10 0.41 4.69 3.09 5.00
105 INT93109 Phosphorylation of NTRK1 5 0.80 3.22 2.99 5.00
106 INT16130 Binding of IGF1 67 0.48 27.43 2.95 5.00
107 INT38987 Protein_catabolism of INS 21 0.99 11.92 2.91 5.00
108 INT15607 Localization of GNRHR 14 0.62 7.56 2.3 5.00
109 INT89308 Positive_regulation of Binding of IFNA1 12 0.49 10.64 2.04 5.00
110 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87 5.00
111 INT57018 Gene_expression of GANAB 9 0.08 3.76 1.79 5.00
112 INT78938 Binding of IGFBP3 40 0.45 27.95 1.73 5.00
113 INT25738 Positive_regulation of Chrng 7 0.43 0.99 1.69 5.00
114 INT110830 Negative_regulation of Mns1 2 0.34 0.91 1.64 5.00
115 INT48616 Positive_regulation of IGFBP1 14 0.43 5.62 1.56 5.00
116 INT154104 Binding of ARID1B 47 0.39 69.82 1.49 5.00
117 INT292921 Regulation of Mns1 1 0.08 0 1.35 5.00
118 INT292920 Negative_regulation of Syt12 1 0.02 0.49 1.27 5.00
119 INT169251 Gene_expression of Phox2b 9 0.70 3.88 1.17 5.00
120 INT80338 Gene_expression of SPTLC1 10 0.78 4.06 1.09 5.00
121 INT286172 Positive_regulation of Protein_catabolism of RLS 1 0.18 7.37 1.02 5.00
122 INT192300 Positive_regulation of Gene_expression of IGFBP1 6 0.60 2.85 0.81 5.00
123 INT116763 Gene_expression of IKBKAP 63 0.78 54.53 0.79 5.00
124 INT248797 Positive_regulation of Mns1 2 0.09 0.4 0.76 5.00
125 INT249049 Positive_regulation of ARID1B 14 0.56 24.77 0.71 5.00
126 INT100601 Localization of PRNP 17 0.66 13.61 0.71 5.00
127 INT158836 Positive_regulation of Localization of TRH 7 0.49 2.61 0.67 5.00
128 INT178752 Binding of IGFBP1 8 0.15 4.58 0.61 5.00
129 INT10791 Localization of Mns1 3 0.48 0.24 0.57 5.00
130 INT37351 Negative_regulation of IKBKAP 16 0.58 9.6 0.56 5.00
131 INT135064 Gene_expression of Preb 2 0.38 0.18 0.54 5.00
132 INT55047 Gene_expression of GNRHR 8 0.78 5.2 0.53 5.00
133 INT213535 Transcription of Phox2b 3 0.62 2.69 0.49 5.00
134 INT324672 Negative_regulation of Gene_expression of CEBPZ 2 0.36 2.75 0.48 5.00
135 INT80624 Regulation of CNBP 5 0.36 3.36 0.45 5.00
136 INT217067 Regulation of Positive_regulation of MAPK8 7 0.45 3.09 0.43 5.00
137 INT263327 Positive_regulation of Positive_regulation of NFKB2 2 0.08 2.95 0.42 5.00
138 INT94146 Regulation of SPTLC1 2 0.51 2.39 0.36 5.00
139 INT152796 Protein_catabolism of RLS 4 0.59 3.64 0.33 5.00
140 INT202176 Gene_expression of MIXL1 4 0.65 1.5 0.29 5.00
141 INT321985 Gene_expression of Etan1 1 0.01 1.5 0.28 5.00
142 INT12531 Localization of GANAB 3 0.09 2.79 0.26 5.00
143 INT292922 Gene_expression of Olr717 1 0.01 0.12 0.19 5.00
144 INT172368 Negative_regulation of Binding of IGF1 3 0.42 1.57 0.18 5.00
145 INT239095 Negative_regulation of PTTG1 2 0.32 8.24 0.09 5.00
146 INT321984 Negative_regulation of Bglu2 1 0.01 1.19 0.08 5.00
147 INT239094 Negative_regulation of Binding of GH1 2 0.34 1.61 0.06 5.00
148 INT177537 Negative_regulation of CSF3R 1 0.17 1.64 0.05 5.00
149 INT309863 Positive_regulation of Gene_expression of ARID1B 3 0.40 2.03 0.05 5.00
150 INT263328 Positive_regulation of KIF20B 1 0.28 2.56 0.04 5.00
151 INT239092 Positive_regulation of Binding of IGFBP1 1 0.04 0.6 0.04 5.00
152 INT231433 Positive_regulation of Binding of IGFBP3 2 0.34 0.6 0.04 5.00
153 INT267705 Protein_catabolism of ARID1B 2 0.71 3.18 0 5.00
154 INT309865 Negative_regulation of Binding of ARID1B 1 0.34 1.49 0 5.00
155 INT263329 Localization of CNBP 1 0.01 1.59 0 5.00
156 INT222723 Negative_regulation of Localization of PRNP 1 0.05 2.06 0 5.00
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