D:Cerebellooculorenal Syndrome

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Disease Term
Synonyms Cerebro Oculo Renal Syndrome, CEREBRO OCULO RENAL SYNDROMES, CEREBROOCULORENAL SYNDROME, Cerebrooculorenal Syndromes, Dystrophies Oculocerebrorenal, DYSTROPHY OCULOCEREBRORENAL, Lowe Bickel Syndrome, Lowe Disease, Lowe Oculocerebrorenal Syndrome, Lowe Syndrome, LOWE TERREY MACLACHLAN SYNDROME
Documents 5
Hot Single Events 11
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cerebellooculorenal Syndrome. They are ordered first by their relevance to Cerebellooculorenal Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT340379 Binding of Rabep1 and Ocrl 1 0.08 0.62 0 95.44
2 INT340377 Binding of Clcn4-2 and Clcn5 1 0.35 0.82 0 80.96
3 INT340380 Binding of Cfl1 and Clcn4-2 1 0.13 0.82 0 80.96
4 INT340378 Binding of Cfl1 and Clcn5 1 0.15 0.82 0 80.56
5 INT266833 Phex Regulation of Gene_expression of Fgf23 1 0.23 0.46 0 5.00
6 INT266834 Pth Negative_regulation of Positive_regulation of Grxcr1 1 0.04 0.51 0 5.00
7 INT266835 Pth Regulation of Slc34a3 1 0.19 0.07 0 5.00
8 INT266836 Pth Regulation of Slc34a1 1 0.09 0.07 0 5.00
9 INT266837 Dmp1 Negative_regulation of Gene_expression of Fgf23 1 0.48 2.41 0 5.00
10 INT266838 Fgf23 Regulation of Slc34a1 1 0.13 0.3 0 5.00
11 INT266839 Fgf23 Negative_regulation of Slc34a1 1 0.21 0.88 0 5.00
12 INT275667 Binding of CYP1B1 and GLC3C 1 0.27 0.99 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cerebellooculorenal Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Cerebellooculorenal Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT340370 Negative_regulation of Ocrl 1 0.43 2.31 0 99.80
2 INT340368 Binding of Ocrl 1 0.37 2.61 0 99.76
3 INT340362 Gene_expression of Ocrl 3 0.67 2.27 0 99.48
4 INT340367 Regulation of Gene_expression of Ocrl 1 0.45 1.11 0 99.48
5 INT340364 Negative_regulation of Gene_expression of Ocrl 1 0.43 1.16 0 98.88
6 INT340366 Gene_expression of Clcn5 1 0.77 4.8 0 97.36
7 INT340374 Binding of Rabep1 1 0.05 0.61 0 95.44
8 INT266822 Negative_regulation of Grxcr1 10 0.10 8.12 0.17 95.36
9 INT266832 Positive_regulation of Grxcr1 9 0.12 7.91 0.19 93.92
10 INT266818 Localization of Grxcr1 7 0.12 3.9 0 83.28
11 INT340361 Binding of Clcn4-2 1 0.30 0.82 0 80.96
12 INT340359 Binding of Clcn5 1 0.48 1.91 0 68.24
13 INT164753 Negative_regulation of Clcn5 2 0.58 5.13 0.2 58.16
14 INT340360 Positive_regulation of Clcn5 1 0.50 1.62 0 58.16
15 INT36040 Localization of Itpr3 21 0.70 4.87 7.77 42.24
16 INT17561 Localization of Car2 303 0.79 60.95 44.52 39.20
17 INT340372 Negative_regulation of Protein_catabolism of Clcn5 1 0.43 1.07 0 38.00
18 INT340365 Protein_catabolism of Clcn5 1 0.99 1.03 0 36.56
19 INT56433 Negative_regulation of Cl 3 0.13 1.87 0.35 35.24
20 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 34.16
21 INT16003 Gene_expression of Phex 3 0.65 4.68 0.77 32.76
22 INT167957 Gene_expression of Grxcr1 8 0.10 3.43 0.14 30.24
23 INT17962 Regulation of Car2 124 0.41 33.98 22.71 25.00
24 INT1893 Localization of Gh 1041 0.79 340.23 256.58 5.00
25 INT14587 Positive_regulation of Cl 44 0.20 20.37 16.72 5.00
26 INT107033 Gene_expression of Slc37a4 66 0.62 27.34 12.35 5.00
27 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 5.00
28 INT67138 Gene_expression of Gc 19 0.31 17.11 4.1 5.00
29 INT14880 Positive_regulation of Car3 14 0.65 9.19 3.73 5.00
30 INT22500 Negative_regulation of Pth 6 0.43 3.41 2.83 5.00
31 INT136964 Gene_expression of Dmp1 10 0.75 3.69 2.83 5.00
32 INT96873 Gene_expression of CYP1B1 28 0.78 11.81 1.09 5.00
33 INT118373 Gene_expression of Fgf23 16 0.77 29.62 1.04 5.00
34 INT118371 Positive_regulation of Fgf23 15 0.69 25.34 0.85 5.00
35 INT218315 Gene_expression of RBP4 25 0.76 18.19 0.85 5.00
36 INT96879 Positive_regulation of CYP1B1 14 0.70 5.73 0.78 5.00
37 INT294932 Negative_regulation of Gc 6 0.17 3.38 0.71 5.00
38 INT173912 Negative_regulation of LRP2 5 0.57 6.22 0.42 5.00
39 INT105007 Binding of MOXD1 2 0.03 1.15 0.29 5.00
40 INT125804 Localization of Pth 9 0.69 3.93 0.29 5.00
41 INT135880 Positive_regulation of Gene_expression of Fgf23 4 0.46 7.52 0.29 5.00
42 INT96887 Regulation of Gene_expression of CYP1B1 2 0.45 0.9 0.2 5.00
43 INT130802 Localization of FGF23 2 0.17 1.78 0.2 5.00
44 INT233570 Gene_expression of Rbp4 4 0.66 3.4 0.17 5.00
45 INT340373 Negative_regulation of Rbp4 1 0.17 1.96 0.16 5.00
46 INT118372 Regulation of Fgf23 4 0.55 3.31 0.15 5.00
47 INT22413 Positive_regulation of Cyp39a1 2 0.08 2.49 0.09 5.00
48 INT117827 Positive_regulation of PHEX 3 0.41 1.59 0.08 5.00
49 INT266826 Binding of Fgf23 1 0.32 1.26 0.07 5.00
50 INT266820 Positive_regulation of Positive_regulation of Grxcr1 1 0.06 1.58 0.06 5.00
51 INT266821 Positive_regulation of Negative_regulation of Grxcr1 1 0.06 1.51 0.06 5.00
52 INT266828 Negative_regulation of Fgf23 3 0.42 5.63 0.04 5.00
53 INT340358 Negative_regulation of Positive_regulation of Cl 1 0.13 0.79 0.04 5.00
54 INT266823 Regulation of Grxcr1 3 0.06 1.4 0.03 5.00
55 INT340375 Negative_regulation of Cubn 1 0.24 0.77 0.03 5.00
56 INT70263 Negative_regulation of Cyp39a1 2 0.05 0.96 0 5.00
57 INT262003 Binding of CYP1B1 3 0.48 3.34 0 5.00
58 INT262005 Regulation of CYP1B1 4 0.62 4.52 0 5.00
59 INT266819 Regulation of Localization of Grxcr1 2 0.06 1.28 0 5.00
60 INT266824 Regulation of Positive_regulation of Fgf23 1 0.27 1.22 0 5.00
61 INT266825 Positive_regulation of Regulation of Fgf23 1 0.46 0.25 0 5.00
62 INT266827 Positive_regulation of Mepe 1 0.67 1.25 0 5.00
63 INT266829 Regulation of Cyp39a1 1 0.02 0.44 0 5.00
64 INT266830 Regulation of Slc34a3 1 0.42 1.85 0 5.00
65 INT266831 Positive_regulation of Slc34a3 1 0.47 1.79 0 5.00
66 INT340363 Regulation of Clcn5 1 0.45 0.85 0 5.00
67 INT340369 Negative_regulation of Tal 1 0.09 1.04 0 5.00
68 INT340371 Regulation of Tal 1 0.10 0.85 0 5.00
69 INT347732 Binding of Shc2 1 0.14 0.58 0 5.00
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