D:Cerebral Toxoplasmosis

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Disease Term
Synonyms Central Nervous System Toxoplasmosis, Intracranial Toxoplasmosis, NEUROTOXOPLASMOSIS, Toxoplasmoses Cerebral, TOXOPLASMOSIS CENTRAL NERVOUS SYSTEM, Toxoplasmosis Intracranial
Documents 57
Hot Single Events 26
Hot Interactions 5

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cerebral Toxoplasmosis. They are ordered first by their relevance to Cerebral Toxoplasmosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT142076 IL4 Negative_regulation of Gene_expression of IFNG 1 0.01 1.58 0.64 99.64
2 INT164431 Ifng Positive_regulation of Il6 1 0.01 1.71 0.29 92.00
3 INT164433 Il12a Positive_regulation of Il6 1 0.01 1.71 0.29 92.00
4 INT164432 Ifng Positive_regulation of Tnf 1 0.01 1.71 0.29 91.52
5 INT164434 Il12a Positive_regulation of Tnf 1 0.00 1.7 0.29 91.52
6 INT142075 IL4 Negative_regulation of Binding of IDO1 1 0.02 2.07 1.19 75.00
7 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19 75.00
8 INT253929 Binding of Vcam1 and Cd99l2 1 0.00 0.61 0.13 5.00
9 INT253930 IFNA1 Positive_regulation of Cdc42ep3 1 0.00 0.65 0.08 5.00
10 INT199041 AGRP Regulation of IGHE 1 0.00 1.39 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cerebral Toxoplasmosis. They are ordered first by their pain relevance and then by number of times they were reported in Cerebral Toxoplasmosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 99.64
2 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 99.64
3 INT133766 Negative_regulation of Fasl 11 0.56 11.28 2.27 99.44
4 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 99.06
5 INT25381 Localization of Csf2 62 0.76 47.48 9.03 98.96
6 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5 98.80
7 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 98.08
8 INT59283 Positive_regulation of Gene_expression of Plg 6 0.25 2.36 1.97 95.80
9 INT10145 Gene_expression of Plg 28 0.62 12.68 7.46 95.44
10 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 95.36
11 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 95.36
12 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89 95.36
13 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3 95.36
14 INT61628 Negative_regulation of Gene_expression of IL4 31 0.55 20.96 8.18 95.36
15 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 92.56
16 INT77146 Binding of IL4 23 0.36 13.69 5.39 92.56
17 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 92.00
18 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 91.52
19 INT39640 Negative_regulation of Gene_expression of Plg 2 0.25 1.13 0.39 89.60
20 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04 88.48
21 INT81628 Positive_regulation of Gene_expression of Fas 32 0.67 38.13 4.23 88.48
22 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 87.72
23 INT117470 Positive_regulation of Positive_regulation of ISYNA1 7 0.51 6.87 1.94 87.72
24 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 87.72
25 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61 87.72
26 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 81.64
27 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 78.92
28 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 77.60
29 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 76.16
30 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98 75.00
31 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77 75.00
32 INT166702 Negative_regulation of Ier2 2 0.20 1.62 0.61 75.00
33 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 75.00
34 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 75.00
35 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 75.00
36 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 75.00
37 INT142081 Binding of IDO1 4 0.21 2.55 1.73 75.00
38 INT142078 Negative_regulation of IDO1 3 0.14 2.59 1.23 75.00
39 INT142080 Protein_catabolism of IDO1 2 0.27 1.47 0.55 75.00
40 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 75.00
41 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 75.00
42 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 75.00
43 INT48908 Transcription of NOS1 27 0.55 13.46 8.39 75.00
44 INT142082 Positive_regulation of IDO1 17 0.60 9.46 6.33 75.00
45 INT142083 Positive_regulation of AIF1 4 0.12 4.86 0.77 75.00
46 INT142079 Negative_regulation of Positive_regulation of AIF1 1 0.00 1.01 0.57 75.00
47 INT265607 Gene_expression of TAF8 11 0.32 9.91 0.35 71.36
48 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 70.96
49 INT16404 Regulation of CD4 54 0.61 33.05 10.29 68.56
50 INT88128 Positive_regulation of Localization of HGF 7 0.45 2.74 0.17 65.96
51 INT86805 Localization of HGF 49 0.71 28.48 6.35 65.48
52 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 59.64
53 INT121784 Regulation of Gene_expression of Fas 7 0.38 5.68 1.86 46.92
54 INT142872 Regulation of Casp8 6 0.29 3.11 0.39 46.92
55 INT256923 Regulation of Gene_expression of Casp8 2 0.11 2.31 0.04 46.92
56 INT116194 Gene_expression of Casp8 14 0.75 14.61 2.13 46.36
57 INT98554 Positive_regulation of Casp8 20 0.67 21.32 2.9 45.76
58 INT104007 Negative_regulation of Positive_regulation of GRIN1 2 0.15 1.5 0.88 45.36
59 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 41.44
60 INT255408 Protein_catabolism of Pymr 2 0.06 1.71 0 22.60
61 INT201453 Protein_catabolism of Hmox1 3 0.95 4.25 0.23 13.52
62 INT271762 Binding of HAND1 3 0.10 3.66 0.31 5.12
63 INT245179 Localization of HAND1 1 0.19 1.09 0 5.12
64 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
65 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
66 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
67 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
68 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 5.00
69 INT65500 Gene_expression of App 605 0.78 429.94 98.31 5.00
70 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
71 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
72 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 5.00
73 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
74 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 5.00
75 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 5.00
76 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 5.00
77 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 5.00
78 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
79 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 5.00
80 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
81 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 5.00
82 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 5.00
83 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 5.00
84 INT9655 Regulation of Il6 98 0.62 70.92 31.95 5.00
85 INT35406 Localization of Tnf 94 0.81 64.63 31.65 5.00
86 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
87 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 5.00
88 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 5.00
89 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67 5.00
90 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
91 INT61664 Regulation of GRIN1 38 0.60 16.45 25.35 5.00
92 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01 5.00
93 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09 5.00
94 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
95 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
96 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62 5.00
97 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 5.00
98 INT87235 Negative_regulation of Il4 54 0.48 31.51 13.15 5.00
99 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94 5.00
100 INT107033 Gene_expression of Slc37a4 66 0.62 27.34 12.35 5.00
101 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 5.00
102 INT57187 Positive_regulation of Gfap 49 0.69 27.59 11.46 5.00
103 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15 5.00
104 INT58904 Localization of TH1L 40 0.68 27.11 10.52 5.00
105 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35 5.00
106 INT186273 Negative_regulation of Il13 33 0.46 22.88 8.65 5.00
107 INT79693 Regulation of Il4 30 0.51 21.96 8.6 5.00
108 INT25392 Positive_regulation of Gene_expression of Csf2 41 0.49 34.28 8.36 5.00
109 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71 5.00
110 INT91667 Localization of IL12A 39 0.74 25.51 7.36 5.00
111 INT11747 Positive_regulation of IL2RA 22 0.67 16.55 6.95 5.00
112 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92 5.00
113 INT17049 Localization of CD4 57 0.75 35.33 6.89 5.00
114 INT112986 Positive_regulation of S100b 19 0.70 17.61 6.86 5.00
115 INT173967 Gene_expression of Mri1 26 0.43 16.67 6.45 5.00
116 INT88245 Gene_expression of Slc11a1 42 0.53 18.86 6.2 5.00
117 INT138915 Gene_expression of Stat1 144 0.77 69.53 5.85 5.00
118 INT116229 Gene_expression of C1qa 28 0.77 18.53 5.35 5.00
119 INT81796 Binding of AGRP 62 0.36 37.19 5.3 5.00
120 INT181395 Gene_expression of Ccl8 11 0.67 13.88 4.56 5.00
121 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 5.00
122 INT186270 Regulation of Il13 13 0.43 11.58 4.19 5.00
123 INT86998 Regulation of HIVEP1 49 0.44 37.83 4 5.00
124 INT134914 Binding of Gfap 21 0.37 8.25 3.67 5.00
125 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6 5.00
126 INT96150 Gene_expression of H2-D1 44 0.27 16.23 3.4 5.00
127 INT28359 Gene_expression of Pdcd1 39 0.57 34.09 3.4 5.00
128 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16 5.00
129 INT109411 Gene_expression of SAT1 61 0.77 67.99 3.08 5.00
130 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73 5.00
131 INT107302 Negative_regulation of Gene_expression of Fasl 7 0.42 8.52 2.54 5.00
132 INT195085 Gene_expression of S100b 12 0.56 12.26 2.33 5.00
133 INT31118 Localization of Casp3 17 0.73 11.55 2.3 5.00
134 INT163063 Positive_regulation of C1qa 10 0.67 6.06 2.29 5.00
135 INT163064 Positive_regulation of Gene_expression of C1qa 9 0.67 6.51 2.29 5.00
136 INT65948 Binding of DNASE1L3 8 0.31 1.38 2.21 5.00
137 INT82587 Positive_regulation of Gene_expression of GRIN1 8 0.67 3.66 2.18 5.00
138 INT96841 Regulation of Slc11a1 9 0.36 6.83 2.14 5.00
139 INT199084 Gene_expression of Cd36 31 0.53 16.94 1.94 5.00
140 INT184031 Gene_expression of Cish 14 0.49 9.82 1.86 5.00
141 INT36018 Negative_regulation of Gene_expression of CD8A 12 0.42 6.66 1.85 5.00
142 INT102843 Negative_regulation of PDC 5 0.57 4.26 1.82 5.00
143 INT215380 Positive_regulation of Gene_expression of Cd36 12 0.47 8.51 1.3 5.00
144 INT100051 Binding of MUC5AC 20 0.32 14.21 1.14 5.00
145 INT89967 Negative_regulation of Gene_expression of Fas 19 0.58 19.28 1.1 5.00
146 INT253925 Positive_regulation of Gene_expression of Pdcd1 5 0.06 5.03 1.08 5.00
147 INT81043 Negative_regulation of Kctd1 9 0.57 7.68 1.06 5.00
148 INT31117 Binding of Casp3 14 0.23 5.27 0.93 5.00
149 INT81794 Regulation of AGRP 12 0.39 4.94 0.9 5.00
150 INT150108 Positive_regulation of Gene_expression of Slc37a4 5 0.35 2.09 0.83 5.00
151 INT203035 Gene_expression of Pdcd1lg2 4 0.58 1.97 0.74 5.00
152 INT253922 Gene_expression of Otc 13 0.17 1.21 0.73 5.00
153 INT221108 Negative_regulation of Slc11a1 5 0.33 3.76 0.69 5.00
154 INT139180 Regulation of Positive_regulation of Fas 2 0.43 2.19 0.69 5.00
155 INT146109 Positive_regulation of Serping1 4 0.59 2.73 0.68 5.00
156 INT236356 Positive_regulation of Binding of Gfap 4 0.44 3.2 0.67 5.00
157 INT247954 Positive_regulation of Pdcd1 5 0.16 4.97 0.65 5.00
158 INT188754 Localization of AGRP 15 0.74 8.88 0.6 5.00
159 INT224635 Positive_regulation of Lgals3bp 3 0.07 2.31 0.58 5.00
160 INT100822 Localization of Fas 8 0.74 6.13 0.48 5.00
161 INT178589 Localization of IL2RA 3 0.68 1.99 0.45 5.00
162 INT189176 Positive_regulation of Localization of TH1L 5 0.23 2.93 0.42 5.00
163 INT210831 Gene_expression of Abca4 7 0.67 1.69 0.32 5.00
164 INT253917 Gene_expression of Rnf123 3 0.08 1.98 0.3 5.00
165 INT233881 Positive_regulation of Cd36 8 0.48 4.68 0.29 5.00
166 INT253918 Positive_regulation of Gene_expression of Rnf123 1 0.07 1.61 0.25 5.00
167 INT253924 Positive_regulation of Gene_expression of Cish 2 0.22 1.67 0.25 5.00
168 INT347940 Regulation of Positive_regulation of Fasl 1 0.30 1.95 0.13 5.00
169 INT227406 Regulation of Bcl2l10 2 0.03 2.99 0.13 5.00
170 INT253916 Binding of Cd99l2 1 0.02 0.61 0.12 5.00
171 INT253923 Binding of Trex1 1 0.29 1.59 0.1 5.00
172 INT184448 Binding of Furin 2 0.36 0.81 0.09 5.00
173 INT253928 Negative_regulation of Binding of Furin 1 0.41 0.82 0.09 5.00
174 INT253921 Positive_regulation of C4a 1 0.32 0.59 0.07 5.00
175 INT190027 Regulation of Apaf1 2 0.16 2.59 0.04 5.00
176 INT297383 Binding of BMP8B 1 0.08 0.34 0.03 5.00
177 INT321555 Negative_regulation of Vcl 3 0.12 2.41 0.03 5.00
178 INT154990 Negative_regulation of TJP1 2 0.20 1.74 0.03 5.00
179 INT185891 Gene_expression of BMP8B 4 0.54 1.58 0 5.00
180 INT297382 Negative_regulation of BMP8B 1 0.09 0.53 0 5.00
181 INT297381 Transcription of BMP8B 1 0.15 0.36 0 5.00
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