D:Cerebrovascular Disease

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Disease Term
Synonyms Brain Vascular Disorder, Brain Vascular Disorders, Cerebrovascular Disorder, Cerebrovascular Disorders, Cerebrovascular Dysfunction, Cerebrovascular Insufficiencies, Cerebrovascular Insufficiency, Cerebrovascular Occlusion, Cerebrovascular Occlusions, CEREBROVASCULAR SYNDROME, Insufficiencies Cerebrovascular
Documents 906
Hot Single Events 140
Hot Interactions 6

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cerebrovascular Disease. They are ordered first by their relevance to Cerebrovascular Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT339275 Il6 Regulation of KRT20 1 0.00 3.11 0.49 95.04
2 INT245216 Binding of C3 and C3AR1 1 0.19 1.21 0.04 93.00
3 INT301907 Binding of THBD and VWF 1 0.02 1.71 0.16 92.72
4 INT245219 Binding of C3AR1 and C5AR1 1 0.34 1.21 0.04 92.60
5 INT245218 Binding of C3 and C5AR1 2 0.29 2.94 0.04 92.60
6 INT320600 TNS3 Regulation of CEBPZ 1 0.29 1.96 0.74 92.56
7 INT122575 Akt1 Positive_regulation of Phosphorylation of Nos3 4 0.37 3.89 0.29 76.56
8 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 75.00
9 INT144588 Binding of EEF1A2 and pad 1 0.36 1.34 0.24 68.60
10 INT177899 Crp Positive_regulation of Positive_regulation of Crp 1 0.01 1.69 0.6 67.60
11 INT265879 IGF1 Regulation of FOXO1 1 0.11 1.37 0.03 64.32
12 INT265884 IGF1 Regulation of CREB1 1 0.13 1.31 0.03 63.52
13 INT265906 IGF1 Regulation of Gsk3b 1 0.25 1.31 0.03 63.04
14 INT265891 IGF1 Regulation of AKT1 1 0.05 1.24 0.03 59.92
15 INT265880 IGF1 Regulation of PIK3CG 1 0.10 1.23 0.03 59.60
16 INT19476 Binding of IL1A and Il6 1 0.00 2.19 0.36 59.16
17 INT19477 Binding of IL1A and Csf2 1 0.00 2.19 0.36 59.16
18 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 45.64
19 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 45.64
20 INT265893 BAD Regulation of FOXO1 1 0.03 1.08 0.06 44.00
21 INT270732 DBP Negative_regulation of SHBG 1 0.00 1.08 0 40.60
22 INT265848 Binding of HSD11B1 and Cand1 1 0.40 0.85 0 37.16
23 INT265883 IGF1 Positive_regulation of Transcription of FOXO1 1 0.17 1.14 0.07 35.04
24 INT81657 Binding of CPOX and PTGS1 5 0.15 1.9 2.37 34.56
25 INT265882 IGF1 Positive_regulation of Transcription of AKT1 1 0.08 1.13 0.07 32.56
26 INT265886 IGF1 Positive_regulation of AKT1 1 0.11 3.06 0.23 27.60
27 INT182126 IRF6 Positive_regulation of Gene_expression of SELE 1 0.03 0.86 0.34 18.64
28 INT262714 ACOT1 Positive_regulation of Negative_regulation of ACHE 1 0.06 1.41 0.08 17.00
29 INT302379 Crp Positive_regulation of Gene_expression of Ccl2 1 0.10 4.58 0.84 11.28
30 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
31 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 5.00
32 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81 5.00
33 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
34 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 5.00
35 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
36 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
37 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
38 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13 5.00
39 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12 5.00
40 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 5.00
41 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
42 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85 5.00
43 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83 5.00
44 INT224410 Binding of CRP and CIMT 3 0.42 10.46 1.2 5.00
45 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18 5.00
46 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11 5.00
47 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 5.00
48 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
49 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98 5.00
50 INT277832 Binding of TNFRSF1B and NPEPPS 1 0.01 1.1 0.88 5.00
51 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87 5.00
52 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69 5.00
53 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 5.00
54 INT339794 Sstr2 Positive_regulation of Gene_expression of Sstr5 1 0.08 0.25 0.64 5.00
55 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
56 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63 5.00
57 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58 5.00
58 INT267707 Binding of Tnf and ARID1B 2 0.20 8.2 0.54 5.00
59 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48 5.00
60 INT171990 Binding of DMD and VDR 5 0.05 2.58 0.39 5.00
61 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 5.00
62 INT255804 DSP Negative_regulation of Gene_expression of Il6 1 0.01 0.36 0.36 5.00
63 INT334393 IL6 Positive_regulation of Tnf 1 0.16 1.41 0.35 5.00
64 INT255803 Cat Negative_regulation of Gene_expression of Il6 1 0.05 0.35 0.35 5.00
65 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34 5.00
66 INT282202 Tcas1 Negative_regulation of NA 1 0.01 0.32 0.34 5.00
67 INT174266 TNF Regulation of Gene_expression of F3 1 0.00 3.2 0.33 5.00
68 INT174265 IL18 Regulation of Gene_expression of F3 1 0.00 3.21 0.33 5.00
69 INT342457 CSF1 Negative_regulation of Gene_expression of CCR4 1 0.00 0.93 0.31 5.00
70 INT177901 Binding of IL6 and Wbc1 1 0.00 1.05 0.31 5.00
71 INT345421 IFNA1 Positive_regulation of Eif2ak2 2 0.03 1.25 0.3 5.00
72 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3 5.00
73 INT278018 Gh Negative_regulation of Phosphorylation of Ins1 1 0.13 1.5 0.29 5.00
74 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 5.00
75 INT265831 BGN Positive_regulation of ADCY1 1 0.01 0.41 0.27 5.00
76 INT154755 Tnf Positive_regulation of Gene_expression of Ccl2 2 0.23 1.7 0.27 5.00
77 INT342458 CSF1 Positive_regulation of Gene_expression of CCL2 1 0.17 0.84 0.27 5.00
78 INT265830 KNG1 Positive_regulation of Localization of BGN 1 0.02 0.33 0.27 5.00
79 INT278015 Gh Regulation of Ins1 1 0.10 1.47 0.27 5.00
80 INT278012 Gh Positive_regulation of Gene_expression of Ins1 1 0.11 1.24 0.26 5.00
81 INT278016 Gh Positive_regulation of Localization of Ins1 1 0.16 1.22 0.26 5.00
82 INT220635 Binding of Lrp1 and Kat5 2 0.09 0.71 0.25 5.00
83 INT342456 AGT Positive_regulation of Gene_expression of CCL2 1 0.07 0.63 0.25 5.00
84 INT177897 Binding of Il1 and Wbc1 1 0.00 0.74 0.25 5.00
85 INT179166 TFPI Positive_regulation of Gene_expression of IL6 1 0.03 0.18 0.25 5.00
86 INT198926 Binding of Apbb1 and Lrp1 5 0.12 2.18 0.24 5.00
87 INT123462 Binding of TNF and Tnfrsf11b 3 0.21 3.52 0.24 5.00
88 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23 5.00
89 INT265828 ACE Regulation of Gene_expression of KNG1 1 0.32 0.83 0.22 5.00
90 INT177895 Binding of Crp and Wbc1 1 0.00 0.45 0.22 5.00
91 INT174861 Binding of FGF2 and VEGFA 1 0.34 0.59 0.2 5.00
92 INT285979 Ros1 Positive_regulation of Trib3 2 0.02 2.18 0.2 5.00
93 INT246468 GHS Regulation of Gh 1 0.05 1.12 0.19 5.00
94 INT206089 Negative_regulation of FOSB Negative_regulation of Gene_expression of PTGS2 1 0.00 0.97 0.19 5.00
95 INT334394 ADIPOQ Negative_regulation of Gene_expression of Tnf 1 0.37 1.06 0.18 5.00
96 INT179158 ATM Regulation of Gene_expression of GOPC 1 0.01 0 0.18 5.00
97 INT179163 ATM Regulation of Gene_expression of IL13 1 0.01 0 0.18 5.00
98 INT179161 ATM Regulation of Gene_expression of IL6 1 0.02 0 0.18 5.00
99 INT179162 ATM Regulation of Gene_expression of IL8 1 0.01 0 0.18 5.00
100 INT264101 Binding of CYP2D6 and Bche 1 0.07 0.33 0.18 5.00
101 INT230455 FOXG1 Negative_regulation of HBS1L 1 0.02 1.73 0.18 5.00
102 INT206081 IL6ST Negative_regulation of IL6 1 0.11 0.81 0.17 5.00
103 INT265827 ACE Negative_regulation of ANGPT2 1 0.09 0.59 0.17 5.00
104 INT265892 IGF1 Positive_regulation of PIK3CG 1 0.18 1.96 0.16 5.00
105 INT206059 IL6 Positive_regulation of INS 1 0.02 1.16 0.16 5.00
106 INT302381 Il33 Regulation of Gene_expression of Il4 1 0.01 0.76 0.16 5.00
107 INT258812 Sugt1 Positive_regulation of Ace 1 0.05 1.26 0.16 5.00
108 INT267138 Binding of CDH5 and PECAM1 2 0.16 2.69 0.16 5.00
109 INT206070 ANG Positive_regulation of Transcription of IL6 1 0.05 1.5 0.15 5.00
110 INT302384 IL6 Positive_regulation of Localization of Crp 1 0.10 1.39 0.15 5.00
111 INT278020 Binding of Gh and Sst 1 0.18 0.16 0.15 5.00
112 INT243524 Positive_regulation of Binding of NTF3 and SOX10 1 0.01 0.54 0.14 5.00
113 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
114 INT243525 Binding of NTF3 and SOX10 1 0.01 0.54 0.14 5.00
115 INT170817 CMA1 Positive_regulation of Gene_expression of AGT 1 0.19 1.41 0.14 5.00
116 INT332689 Binding of Edn1 and Ros1 1 0.08 0.71 0.14 5.00
117 INT139849 Binding of App and Bace1 7 0.41 0.85 0.13 5.00
118 INT206065 EDN1 Positive_regulation of IL6 1 0.03 0.47 0.12 5.00
119 INT220639 Binding of Apbb1 and Ighd 1 0.12 0.31 0.12 5.00
120 INT307698 Binding of Crp and pad 1 0.04 3.71 0.12 5.00
121 INT332687 Ros1 Positive_regulation of Crk 1 0.17 0.77 0.12 5.00
122 INT220622 App Positive_regulation of Rip 2 0.14 0.24 0.12 5.00
123 INT220633 Binding of Kat5 and Ighd 1 0.09 0.32 0.12 5.00
124 INT332685 Trib3 Positive_regulation of Binding of Ros1 1 0.01 0.74 0.12 5.00
125 INT179160 IL6 Regulation of Gene_expression of IL13 1 0.03 0.12 0.11 5.00
126 INT342459 CXCR3 Positive_regulation of CRTC1 1 0.00 0.59 0.11 5.00
127 INT179159 IL8 Regulation of Gene_expression of IL6 1 0.02 0.12 0.11 5.00
128 INT179165 IL8 Regulation of Gene_expression of IL13 1 0.02 0.12 0.11 5.00
129 INT246466 GHS Positive_regulation of GHS Regulation of Gh 1 0.01 0.6 0.1 5.00
130 INT265888 BCL2 Regulation of Gene_expression of BAD 1 0.04 1.08 0.1 5.00
131 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1 5.00
132 INT173948 Gh Positive_regulation of Gene_expression of IGF1 2 0.36 0.77 0.1 5.00
133 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1 5.00
134 INT265889 BAX Regulation of Gene_expression of BAD 1 0.06 1.08 0.1 5.00
135 INT286432 Binding of ANTXR2 and Gtf3a 1 0.00 3.56 0.1 5.00
136 INT264085 CYP2C19 Regulation of CYP3A4 1 0.02 0 0.09 5.00
137 INT249117 Binding of Abl1 and Bcr 4 0.36 2.22 0.09 5.00
138 INT246467 GHS Regulation of Localization of Gh 1 0.03 0.52 0.09 5.00
139 INT270731 Binding of AGTR1 and ACE 1 0.02 0.67 0.09 5.00
140 INT302385 Il1b Positive_regulation of Nfib Positive_regulation of Gene_expression of Ccl2 1 0.00 1.48 0.09 5.00
141 INT264103 Cyp2e1 Regulation of CYP2C9 1 0.04 0 0.09 5.00
142 INT332688 Ros1 Positive_regulation of Binding of Edn1 1 0.10 0.57 0.09 5.00
143 INT267684 Binding of INS and ARID1B 3 0.10 6.08 0.09 5.00
144 INT264106 Cyp1a2 Regulation of CYP2D6 1 0.06 0 0.09 5.00
145 INT206042 Negative_regulation of FDPS Negative_regulation of Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
146 INT265887 IGF1 Negative_regulation of BCL2 1 0.09 1.02 0.09 5.00
147 INT308225 Alb Positive_regulation of Binding of EIF4G2 1 0.02 0.33 0.09 5.00
148 INT351032 Binding of CD80 and CD96 1 0.01 0.36 0.09 5.00
149 INT239643 Binding of BCL2 and BCL2L11 3 0.16 2.26 0.09 5.00
150 INT265878 IGF1 Negative_regulation of Binding of BCL2 and BCL2L11 1 0.03 1.03 0.09 5.00
151 INT264104 Cyp1a2 Regulation of CYP2C9 1 0.04 0 0.09 5.00
152 INT264083 CYP2C19 Regulation of CYP2D6 1 0.05 0 0.09 5.00
153 INT351031 Binding of CD28 and CD96 1 0.02 0.36 0.09 5.00
154 INT206054 RAC1 Positive_regulation of STAT3 1 0.07 0.11 0.09 5.00
155 INT302382 Il1b Positive_regulation of Gene_expression of Ccl2 1 0.00 1.39 0.09 5.00
156 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09 5.00
157 INT177898 Binding of Crp and Wbc1 1 0.00 0.49 0.09 5.00
158 INT302380 Tnf Positive_regulation of Nfib 1 0.00 1.41 0.09 5.00
159 INT264084 CYP2C19 Regulation of CYP2C9 1 0.03 0 0.09 5.00
160 INT206075 Negative_regulation of FDPS Negative_regulation of Binding of GGPS1 1 0.01 0 0.09 5.00
161 INT264102 Cyp1a2 Regulation of CYP3A4 1 0.03 0 0.09 5.00
162 INT264107 Cyp2e1 Regulation of CYP2D6 1 0.05 0 0.09 5.00
163 INT264105 Cyp2e1 Regulation of CYP3A4 1 0.02 0 0.09 5.00
164 INT206078 Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
165 INT302383 Il1b Positive_regulation of Nfib 1 0.00 1.42 0.09 5.00
166 INT206072 ANG Positive_regulation of IL6 1 0.05 0.5 0.08 5.00
167 INT196337 Binding of CDSN and HBM 1 0.00 0.79 0.08 5.00
168 INT309390 Gene_expression of Sod2 Negative_regulation of Nos3 1 0.31 0.2 0.08 5.00
169 INT206080 ANG Regulation of Gene_expression of IL6 1 0.03 0.4 0.07 5.00
170 INT201227 C2 Regulation of CEBPZ 2 0.06 1.19 0.07 5.00
171 INT220629 Gene_expression of Bace1 Positive_regulation of Localization of Il1r2 1 0.17 0.19 0.07 5.00
172 INT265877 IGF1 Regulation of Binding of GH1 and IGF1 1 0.03 0.47 0.07 5.00
173 INT206063 ANG Positive_regulation of Gene_expression of KRT20 1 0.00 1.01 0.07 5.00
174 INT267137 ICAM1 Regulation of ITGAL 2 0.12 0.57 0.07 5.00
175 INT220638 Gene_expression of Bace2 Positive_regulation of Localization of Il1r2 1 0.13 0.19 0.07 5.00
176 INT339272 VDR Positive_regulation of Gene_expression of KRT20 1 0.00 0.07 0.05 5.00
177 INT206087 RAC1 Positive_regulation of Gene_expression of STAT3 1 0.08 0.05 0.05 5.00
178 INT319578 CYP3A4 Regulation of ALPPL2 1 0.00 0.56 0.05 5.00
179 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04 5.00
180 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04 5.00
181 INT206073 Negative_regulation of RAC1 Positive_regulation of IL6 1 0.14 0.06 0.04 5.00
182 INT206067 Gene_expression of RAC1 Positive_regulation of Positive_regulation of IL6 1 0.16 0.07 0.04 5.00
183 INT267685 Binding of CENPJ and ARID1B 1 0.09 0.58 0.04 5.00
184 INT206068 RAC1 Positive_regulation of IL6 1 0.16 0.06 0.04 5.00
185 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04 5.00
186 INT206071 IRF6 Positive_regulation of Positive_regulation of IL1B 1 0.00 0.58 0.03 5.00
187 INT206076 IL6 Positive_regulation of Positive_regulation of STAT3 1 0.19 0.3 0.03 5.00
188 INT206061 RAC1 Positive_regulation of Positive_regulation of STAT3 1 0.07 0.43 0.03 5.00
189 INT267686 Binding of RYBP and CENPJ 1 0.01 0.12 0.03 5.00
190 INT265881 GHRH Positive_regulation of GHR 1 0.05 0.05 0.03 5.00
191 INT285406 ELF3 Positive_regulation of Binding of ROS1 1 0.08 0.9 0.03 5.00
192 INT285407 ELF3 Regulation of ICAM1 1 0.03 0.91 0.03 5.00
193 INT236078 Binding of AGER and HLA-DMA 1 0.08 0.81 0 5.00
194 INT220625 Negative_regulation of Binding of App and Bace1 1 0.44 0.09 0 5.00
195 INT220631 Gene_expression of Gga1 Positive_regulation of Bace1 2 0.24 0 0 5.00
196 INT352175 USE1 Regulation of NAGA 1 0.01 0.33 0 5.00
197 INT206085 FDPS Positive_regulation of AGFG1 1 0.00 0.4 0 5.00
198 INT278014 Ptprf Regulation of Localization of Gh 1 0.61 0.31 0 5.00
199 INT206058 EGFR Negative_regulation of Gene_expression of IL6 1 0.07 0.62 0 5.00
200 INT175832 Binding of GML and SLC25A11 1 0.10 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cerebrovascular Disease. They are ordered first by their pain relevance and then by number of times they were reported in Cerebrovascular Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 100.00
2 INT147793 Localization of COPD 70 0.64 89.01 7.3 100.00
3 INT9080 Regulation of PPBP 17 0.44 5.75 4.3 100.00
4 INT127283 Regulation of Gene_expression of HMOX1 14 0.61 11.8 1.28 99.98
5 INT28861 Binding of Gh 61 0.46 25.61 6.38 99.92
6 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 99.52
7 INT39712 Binding of pad 82 0.48 110.92 10.33 99.24
8 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 99.08
9 INT52696 Positive_regulation of Ptgs2 48 0.70 27.65 14.44 98.96
10 INT1335 Negative_regulation of Oprl1 123 0.59 18.02 77.13 98.96
11 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71 98.96
12 INT28326 Positive_regulation of Negative_regulation of Oprl1 6 0.44 2.01 3.78 98.96
13 INT16068 Gene_expression of SERPINB1 27 0.60 20.51 6.56 98.80
14 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 98.76
15 INT39301 Gene_expression of Chd7 50 0.26 27.06 8.13 98.68
16 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 98.64
17 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 98.64
18 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 98.52
19 INT160568 Positive_regulation of PADI4 7 0.45 10.5 0.41 98.36
20 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 98.36
21 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 98.20
22 INT22032 Positive_regulation of Negative_regulation of CEBPZ 4 0.41 0.82 0.81 98.20
23 INT75742 Binding of RLS 86 0.42 95.27 19.04 98.12
24 INT7313 Negative_regulation of CDNF 7 0.05 2.53 2.34 98.00
25 INT6852 Localization of TNF 883 0.81 705.95 270.84 97.92
26 INT12082 Localization of IL6 365 0.81 241.78 105.78 97.92
27 INT131296 Positive_regulation of Bace1 208 0.70 170.1 15.79 97.60
28 INT45530 Regulation of F13a1 1 0.30 0.86 0.81 97.60
29 INT124860 Gene_expression of Bace1 330 0.78 157.11 31.65 97.60
30 INT156489 Positive_regulation of Gene_expression of Bace1 67 0.69 41.07 7.02 97.60
31 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66 97.44
32 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 97.04
33 INT12250 Negative_regulation of Mtr 19 0.50 6.9 5.35 96.92
34 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 96.88
35 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 96.56
36 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 96.52
37 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 96.36
38 INT30382 Negative_regulation of Ednra 21 0.42 12.06 8.19 96.24
39 INT6728 Gene_expression of Ednra 43 0.65 13.41 17.38 96.24
40 INT154104 Binding of ARID1B 47 0.39 69.82 1.49 96.12
41 INT53594 Binding of Csrp1 5 0.32 11.87 3.84 96.08
42 INT321183 Regulation of Binding of Csrp1 1 0.11 2.64 0.98 96.08
43 INT6727 Positive_regulation of Ednra 27 0.64 18.75 8.71 95.92
44 INT8757 Binding of ACHE 10 0.48 5.84 1.72 95.84
45 INT100458 Positive_regulation of LTA 11 0.49 6.55 0.8 95.56
46 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92 95.52
47 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 95.50
48 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 95.24
49 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 95.20
50 INT82966 Transcription of Crp 14 0.70 9.91 2.61 95.16
51 INT320566 Positive_regulation of Transcription of Crp 2 0.06 2.36 0.24 95.16
52 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 94.56
53 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 94.44
54 INT102187 Gene_expression of SH2B2 23 0.59 26.54 4.39 94.32
55 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47 94.24
56 INT21953 Binding of Ednra 12 0.33 4.72 4.56 93.96
57 INT42121 Negative_regulation of Localization of PLEK 4 0.42 1.92 0.61 93.92
58 INT132417 Transcription of ANXA5 2 0.59 1.82 0.95 93.76
59 INT228294 Binding of RRAD 2 0.00 2.55 0 93.76
60 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 93.68
61 INT50671 Regulation of Gene_expression of CPOX 45 0.54 30.99 13.83 93.68
62 INT339080 Positive_regulation of Binding of PADI4 1 0.03 1.3 0 93.64
63 INT12324 Positive_regulation of PRTN3 26 0.70 18.82 4.55 93.48
64 INT3366 Localization of PLEK 44 0.78 15.83 9.55 93.20
65 INT229632 Binding of PADI4 21 0.48 37.45 0.34 93.12
66 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 93.04
67 INT35584 Binding of ACLY 22 0.35 31.78 7.17 93.00
68 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15 92.72
69 INT10893 Binding of VWF 27 0.47 25.02 2.82 92.72
70 INT45613 Positive_regulation of pad 23 0.50 24.18 4.8 92.32
71 INT50080 Binding of APOE 38 0.45 29.61 2.67 91.72
72 INT24019 Negative_regulation of HPS1 7 0.37 7.94 1.04 91.72
73 INT301343 Negative_regulation of Positive_regulation of ELL 1 0.08 1.64 0.17 91.64
74 INT238096 Positive_regulation of ELL 4 0.09 2.68 0.16 91.64
75 INT3794 Regulation of CDNF 16 0.16 2.99 5.59 91.52
76 INT139863 Binding of amd 27 0.41 41.3 0.91 91.48
77 INT64171 Regulation of CPOX 109 0.36 55.36 32.96 91.44
78 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62 91.32
79 INT144490 Regulation of Gene_expression of Tnfsf11 14 0.58 14.09 2.39 91.12
80 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83 91.04
81 INT80329 Positive_regulation of THBD 12 0.47 20.96 2.45 90.64
82 INT198669 Binding of THBD 5 0.10 4.45 0.75 90.64
83 INT86184 Negative_regulation of Acsl1 10 0.34 20.45 2.23 90.48
84 INT10565 Gene_expression of MRXS5 94 0.53 37.35 19.08 90.16
85 INT72021 Localization of Ednra 7 0.58 3.13 1.53 90.16
86 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 89.92
87 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 89.80
88 INT216512 Gene_expression of C3AR1 13 0.70 8.44 1.31 89.44
89 INT25503 Gene_expression of C5AR1 22 0.75 21.88 4.16 89.04
90 INT116527 Positive_regulation of Gene_expression of HMOX1 29 0.70 25.79 4.87 88.96
91 INT135773 Negative_regulation of Gene_expression of HMOX1 31 0.53 28.31 3.32 88.96
92 INT2532 Negative_regulation of Cebpz 98 0.00 53.06 28.57 88.72
93 INT198904 Localization of Lrp1 11 0.62 3.25 1.01 88.56
94 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 88.40
95 INT111199 Gene_expression of Acly 11 0.16 5.65 0.78 88.20
96 INT130344 Gene_expression of APOH 3 0.34 2.87 0.32 88.20
97 INT72948 Localization of Ppbp 1 0.01 1.19 0.19 87.76
98 INT812 Localization of INS 1026 0.81 515.6 145.31 87.72
99 INT11625 Localization of App 98 0.78 55.46 20.86 87.28
100 INT41358 Localization of Pf4 11 0.79 6.06 2.89 87.16
101 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05 87.12
102 INT259039 Positive_regulation of Binding of ACLY 1 0.09 1.85 0.09 87.12
103 INT193837 Localization of Aplp1 2 0.45 1.85 0.06 87.08
104 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 86.92
105 INT193831 Localization of Aplp2 2 0.42 1.85 0.06 86.80
106 INT18143 Gene_expression of Tbxas1 9 0.56 5.89 2.39 86.72
107 INT322081 Positive_regulation of Abcd2 1 0.38 2.29 0.2 86.44
108 INT61423 Gene_expression of Egfl7 23 0.14 24.96 0.66 86.36
109 INT88571 Positive_regulation of Tcas1 4 0.34 2.08 4.42 86.04
110 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46 85.60
111 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 85.44
112 INT220608 Localization of Il1r2 5 0.24 2.46 0.44 85.36
113 INT117039 Localization of Selplg 2 0.68 2.22 0.41 85.36
114 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 85.28
115 INT169818 Negative_regulation of Notch3 1 0.38 1.19 0.06 85.24
116 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 85.12
117 INT7105 Gene_expression of pad 54 0.77 63.68 8.8 84.96
118 INT61791 Positive_regulation of SH2B2 9 0.50 8.36 2.99 84.88
119 INT259038 Negative_regulation of Positive_regulation of SH2B2 1 0.25 1.83 0.09 84.88
120 INT45612 Negative_regulation of pad 8 0.37 6.74 2.57 84.88
121 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 84.64
122 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 84.20
123 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 84.16
124 INT80419 Gene_expression of Kdm5d 50 0.62 22.49 6.1 83.72
125 INT9374 Regulation of Plat 19 0.61 6.04 2.55 83.44
126 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 83.40
127 INT9296 Negative_regulation of PLEK 100 0.57 36.65 27.52 83.40
128 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 83.16
129 INT3323 Gene_expression of ALAS2 10 0.58 7.51 0.21 83.12
130 INT70970 Binding of COPD 144 0.42 180.34 18.29 82.40
131 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 81.92
132 INT14009 Gene_expression of Sst 66 0.77 19.6 37.3 81.84
133 INT52349 Gene_expression of CHM 7 0.77 17.33 0.28 81.52
134 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 81.32
135 INT346565 Positive_regulation of Sh3gl3 1 0.26 2.93 0.42 81.16
136 INT159127 Gene_expression of Nps 49 0.75 16.91 12.06 80.92
137 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 80.88
138 INT1530 Regulation of Gh 382 0.61 115.96 112.47 80.80
139 INT9199 Positive_regulation of CEBPZ 111 0.67 30.99 28.45 80.40
140 INT242259 Negative_regulation of Positive_regulation of CEBPZ 4 0.48 1.44 0.59 80.40
141 INT24735 Regulation of TF 10 0.44 5.55 0.65 79.84
142 INT259033 Gene_expression of LCA5L 1 0.01 2.71 0.16 79.76
143 INT9079 Gene_expression of PPBP 52 0.75 31.2 21.52 79.52
144 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 79.52
145 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 79.44
146 INT263328 Positive_regulation of KIF20B 1 0.28 2.56 0.04 79.32
147 INT57562 Gene_expression of GLA 52 0.77 24.62 6.14 79.24
148 INT42243 Positive_regulation of Negative_regulation of Maoa 5 0.50 2.15 3.59 78.96
149 INT94423 Binding of ALAS2 4 0.32 2.1 0.61 78.84
150 INT119708 Transcription of VDR 11 0.71 5.43 0.48 78.80
151 INT249 Localization of GHRH 215 0.80 78.02 51.87 78.72
152 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 78.64
153 INT3321 Positive_regulation of ALAS2 10 0.51 3.08 0.32 78.48
154 INT252 Localization of GH1 529 0.80 227.4 122.05 78.08
155 INT5286 Gene_expression of ANTXR2 46 0.75 21.06 3.41 77.60
156 INT220588 Transcription of Nrg1 1 0.41 0.64 0 77.60
157 INT286431 Negative_regulation of Gene_expression of ANTXR2 1 0.21 1.52 0 77.60
158 INT1281 Negative_regulation of Maoa 203 0.59 22.47 91.66 77.44
159 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21 77.36
160 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 76.84
161 INT104284 Positive_regulation of Notch3 7 0.50 5.57 0.99 76.80
162 INT77852 Binding of Chd7 8 0.31 4.1 2.51 76.56
163 INT1893 Localization of Gh 1041 0.79 340.23 256.58 76.52
164 INT10147 Gene_expression of Serpinc1 28 0.76 17.73 5.77 76.52
165 INT214 Localization of AVP 370 0.81 208.51 91.09 76.40
166 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 76.32
167 INT35143 Negative_regulation of ANGPTL5 28 0.54 18.59 3.14 76.20
168 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 76.16
169 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93 76.16
170 INT10207 Gene_expression of PADI4 22 0.75 23.49 1.74 76.08
171 INT177337 Localization of VDR 6 0.73 3.44 0.59 75.84
172 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 75.68
173 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 75.68
174 INT246551 Negative_regulation of Serpinb12 1 0.01 2.57 0.17 75.64
175 INT309385 Positive_regulation of Phosphorylation of Nos3 5 0.48 2.98 0.09 75.52
176 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13 75.28
177 INT9650 Gene_expression of LPA 141 0.75 104.57 29 75.20
178 INT43984 Regulation of Gene_expression of LPA 7 0.49 6.3 0.61 75.20
179 INT122572 Phosphorylation of Nos3 37 0.65 25.23 0.75 75.12
180 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 75.00
181 INT9012 Localization of Vip 283 0.81 31.71 106.16 75.00
182 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87 75.00
183 INT54978 Binding of EDNRA 36 0.41 14.97 7.86 75.00
184 INT5782 Gene_expression of Edn3 17 0.67 3.38 3.65 75.00
185 INT2774 Binding of Crp 241 0.48 195.89 44.39 74.72
186 INT110209 Localization of Notch3 2 0.75 1.82 0.15 73.84
187 INT185156 Gene_expression of T2dm2 9 0.45 10.44 0.56 73.28
188 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64 73.20
189 INT17101 Positive_regulation of Gene_expression of Edn1 24 0.69 24.9 8.86 73.20
190 INT65500 Gene_expression of App 605 0.78 429.94 98.31 73.12
191 INT346566 Negative_regulation of Positive_regulation of Sh3gl3 1 0.14 0.69 0 73.04
192 INT55784 Negative_regulation of Neu1 4 0.24 1.93 0.33 72.96
193 INT111072 Protein_catabolism of Bace1 26 0.98 14.07 2.41 72.88
194 INT111071 Positive_regulation of Protein_catabolism of Bace1 6 0.50 2.52 0.77 72.88
195 INT167461 Gene_expression of AHSG 5 0.75 4.59 1.53 72.80
196 INT167460 Regulation of AHSG 2 0.36 3.85 1.23 72.80
197 INT329536 Regulation of Gene_expression of AHSG 1 0.26 2.19 0.81 72.80
198 INT140288 Localization of Pon1 4 0.78 6.15 1.15 72.64
199 INT303836 Positive_regulation of Localization of Pon1 1 0.36 1.07 0.09 72.64
200 INT161085 Positive_regulation of Notch3 4 0.41 4.36 0.27 72.00
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