D:Cervical Cancer

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Disease Term
Synonyms Cancer Cervix, Cancer Of Cervix, Cancer Of The Cervix, CANCER OF THE UTERINE CERVIX, Cancer Uterine Cervical, Cancers Cervix, CANCERS OF THE CERVIX, Cancers Uterine Cervical, CERVICAL CANCER UTERINE, Cervical Cancers, CERVICAL CANCERS UTERINE
Documents 882
Hot Single Events 200
Hot Interactions 19

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cervical Cancer. They are ordered first by their relevance to Cervical Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT244401 Binding of HPV6AI1 and HEPACAM 1 0.00 4.33 0 100.00
2 INT235648 Binding of EFNA1 and EPHA2 1 0.23 1.3 0 99.56
3 INT351422 Mfng Negative_regulation of Jag1 1 0.06 1.29 0.07 99.16
4 INT259050 Binding of HPV18I1 and OPN1LW 1 0.01 1.19 0 98.24
5 INT315068 Binding of AKT1 and PAR4 1 0.34 4.41 0 98.00
6 INT259049 Binding of BAK1 and HPV18I1 1 0.00 1.19 0 97.84
7 INT189696 PRKCA Negative_regulation of Negative_regulation of TEP1 1 0.02 0.15 0.5 96.68
8 INT189680 PRKCA Negative_regulation of TEP1 1 0.02 0.15 0.5 96.68
9 INT189675 Negative_regulation of PRKCA Negative_regulation of TEP1 1 0.02 0.15 0.5 96.68
10 INT200651 AKT2 Regulation of AKT1 1 0.31 0.21 0 96.44
11 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 96.16
12 INT291355 CXCL12 Positive_regulation of Gene_expression of HGF 1 0.06 1.53 0.06 96.16
13 INT315066 AKT1 Negative_regulation of PAR4 1 0.39 1.8 0.03 95.80
14 INT200642 GOPC Regulation of AKT1 1 0.14 0.2 0 95.68
15 INT269061 Binding of Il6 and Il6ra 3 0.04 2.59 0.45 94.76
16 INT315061 PAR4 Positive_regulation of Gene_expression of TNF 1 0.10 1.95 0 90.20
17 INT241401 VEGFA Positive_regulation of Gene_expression of Gopc 1 0.11 0.85 0.25 89.40
18 INT200646 AKT1 Regulation of CASP9 1 0.10 1.09 0 86.00
19 INT189688 PRKCA Regulation of Transcription of TERT 1 0.13 0.2 0.5 84.64
20 INT300899 IGF2BP3 Positive_regulation of IGF2 1 0.37 1.06 0 75.68
21 INT351730 CALR Positive_regulation of Positive_regulation of ROS1 1 0.02 0.72 0 73.04
22 INT269138 Binding of Il6ra and Rps7 1 0.01 0.85 0 73.04
23 INT351731 SSD Positive_regulation of Positive_regulation of ROS1 1 0.18 0.71 0 72.72
24 INT269140 Binding of Il6 and Rps7 1 0.02 0.85 0 71.76
25 INT265423 Ccl21a Positive_regulation of Gene_expression of CXCL10 1 0.30 0.88 0.1 71.32
26 INT265388 CCL21 Positive_regulation of Gene_expression of CXCL9 1 0.13 0.88 0.1 71.32
27 INT265422 Ccl21a Positive_regulation of Gene_expression of CXCL9 1 0.24 0.88 0.1 71.32
28 INT265389 CCL21 Positive_regulation of Gene_expression of CXCL10 1 0.16 0.88 0.1 71.32
29 INT351323 Nts Regulation of Localization of Calca 1 0.01 0.6 0.85 70.40
30 INT235651 TP73 Regulation of EPHA2 1 0.15 0.98 0 69.36
31 INT235647 TP63 Regulation of EPHA2 1 0.15 0.97 0 69.36
32 INT235645 TP53 Regulation of EPHA2 1 0.10 0.97 0 69.36
33 INT235649 TP73 Regulation of EFNA1 1 0.09 0.97 0 68.96
34 INT235646 TP63 Regulation of EFNA1 1 0.09 0.97 0 68.96
35 INT235650 TP53 Regulation of EFNA1 1 0.06 0.97 0 68.96
36 INT241400 Epas1 Positive_regulation of Gene_expression of VEGFA 1 0.03 1.09 0.07 65.76
37 INT302175 BAX Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06 65.44
38 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06 65.44
39 INT259051 Binding of TP53 and UBE3A 1 0.01 3.48 0 64.96
40 INT351322 Nts Regulation of Localization of Napa 1 0.01 0.56 0.77 64.48
41 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06 64.32
42 INT302129 BAX Regulation of Positive_regulation of CASP3 1 0.02 0.69 0.06 64.32
43 INT200650 HDAC4 Regulation of Gene_expression of AKT1 1 0.16 0.66 0 63.84
44 INT259082 Binding of HPV18I1 and Hbb-ar 1 0.00 1.36 0 52.40
45 INT259081 Binding of Hbb-ar and ENOPH1 1 0.00 1.36 0 52.24
46 INT326167 Binding of CD4 and Tmed8 1 0.47 0.29 0 51.36
47 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0 51.28
48 INT284232 Binding of TP53 and HNRNPUL1 1 0.26 0.88 0 51.12
49 INT284231 Binding of TP53 and C4orf3 1 0.02 0.88 0 50.20
50 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0 49.76
51 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0 49.20
52 INT189681 Negative_regulation of PRKCA Negative_regulation of Gene_expression of METTL3 1 0.00 0.16 0.41 44.08
53 INT300898 IGF2BP3 Regulation of Gene_expression of IGF2 1 0.21 0.38 0 42.88
54 INT350428 Binding of AKT1 and ATF3 1 0.10 1.7 0 41.12
55 INT241262 TP53 Positive_regulation of Gene_expression of OPCML 1 0.31 1.22 0 32.28
56 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07 28.00
57 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07 28.00
58 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07 28.00
59 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07 28.00
60 INT351423 Sparc Positive_regulation of Mmp2 1 0.02 1.31 0.04 26.72
61 INT241256 TP53 Regulation of OPCML 1 0.12 1.31 0 24.96
62 INT269139 Binding of Csnk2a2 and Sub1 1 0.02 0.68 0 19.68
63 INT350433 KRAS Regulation of Gene_expression of BRAF 1 0.08 1.77 0 18.16
64 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22 15.04
65 INT197095 IL1B Regulation of Positive_regulation of TNF 1 0.01 0.64 0.19 15.04
66 INT197093 TNF Regulation of Positive_regulation of IL1B 1 0.01 0.64 0.19 15.04
67 INT197098 TNF Regulation of FLT4 1 0.14 0.66 0.19 15.04
68 INT175727 IL1B Regulation of VEGFA 2 0.04 0.7 0.19 14.72
69 INT197097 IL1B Regulation of FLT4 1 0.03 0.66 0.19 14.72
70 INT350426 Binding of BRAF and KRAS 1 0.05 1.78 0 9.92
71 INT348533 Positive_regulation of Binding of FOSL2 and JUN 1 0.09 0.32 0 7.92
72 INT348524 Binding of FOSL2 and JUN 1 0.07 0.59 0 7.92
73 INT220916 Positive_regulation of Binding of JUN and JUND 2 0.18 0.53 0.07 7.04
74 INT220911 Binding of JUN and JUND 2 0.14 1.08 0.07 7.04
75 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
76 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
77 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 5.00
78 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
79 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
80 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
81 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 5.00
82 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27 5.00
83 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15 5.00
84 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
85 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06 5.00
86 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
87 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 5.00
88 INT178663 Binding of CXCR3 and TH1L 2 0.04 2.24 1.01 5.00
89 INT44442 GNRH1 Positive_regulation of Localization of PLOD1 3 0.50 0.78 0.86 5.00
90 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82 5.00
91 INT113552 Binding of PLAU and PLAUR 4 0.31 3.09 0.72 5.00
92 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71 5.00
93 INT189704 PRKCA Regulation of CHKB 1 0.13 0.18 0.66 5.00
94 INT299793 Positive_regulation of Binding of CD86 and CTLA4 1 0.17 1.64 0.63 5.00
95 INT299792 Positive_regulation of Binding of CD80 and CTLA4 1 0.17 1.63 0.63 5.00
96 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 5.00
97 INT158400 Binding of CD80 and CD86 3 0.36 0.76 0.48 5.00
98 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
99 INT299789 IL4 Negative_regulation of Gene_expression of RAE1 1 0.00 0.84 0.41 5.00
100 INT316493 Il6 Positive_regulation of Il11ra1 1 0.64 1.69 0.4 5.00
101 INT189689 CHKB Negative_regulation of Positive_regulation of PRKCA 1 0.11 0 0.4 5.00
102 INT299786 IL4 Negative_regulation of Gene_expression of CD5 1 0.07 0.82 0.4 5.00
103 INT299790 IL4 Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37 5.00
104 INT178217 IFNA1 Regulation of Cxcl10 1 0.01 0.86 0.37 5.00
105 INT299788 INCENP Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37 5.00
106 INT178218 IFNA1 Regulation of Tlr7 1 0.04 0.87 0.37 5.00
107 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35 5.00
108 INT189687 INSRR Negative_regulation of Transcription of TERT 1 0.00 0.24 0.35 5.00
109 INT310900 Binding of DEFB1 and Kdm5d 1 0.10 1.98 0.33 5.00
110 INT299791 Negative_regulation of Binding of CD28 and CTLA4 1 0.18 0.77 0.32 5.00
111 INT316488 Il22 Positive_regulation of Il10 1 0.29 0.63 0.32 5.00
112 INT316483 Il22ra1 Positive_regulation of Il10 1 0.27 0.62 0.31 5.00
113 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
114 INT316487 Il22 Regulation of Il22ra1 1 0.12 0.61 0.31 5.00
115 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 5.00
116 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 5.00
117 INT346196 AMELX Negative_regulation of CRP 1 0.04 0.36 0.26 5.00
118 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26 5.00
119 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 0.02 1.51 0.25 5.00
120 INT258521 EGFR Positive_regulation of MMP2 1 0.39 0.91 0.24 5.00
121 INT189692 INSRR Positive_regulation of PRKCA 1 0.00 0 0.24 5.00
122 INT189646 CHKB Negative_regulation of ASAP1 Negative_regulation of Gene_expression of DAG1 1 0.04 0 0.24 5.00
123 INT189674 CHKB Negative_regulation of ASAP1 1 0.08 0 0.24 5.00
124 INT189693 CHKB Positive_regulation of PRKCA 1 0.11 0 0.24 5.00
125 INT189670 CHKB Negative_regulation of Gene_expression of DAG1 1 0.11 0 0.24 5.00
126 INT189700 CHKB Negative_regulation of PRKCA 1 0.11 0 0.24 5.00
127 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24 5.00
128 INT189645 CHKB Negative_regulation of ASAP1 Negative_regulation of PRKCA 1 0.04 0 0.24 5.00
129 INT258565 EGFR Positive_regulation of Meta 1 0.39 0.89 0.23 5.00
130 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23 5.00
131 INT316491 Socs3 Positive_regulation of Il11ra1 1 0.45 0.92 0.22 5.00
132 INT291352 Positive_regulation of CXCL12 Positive_regulation of ERBB2 1 0.17 0.88 0.22 5.00
133 INT299787 Binding of IL2 and ISG20 1 0.04 0.82 0.21 5.00
134 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21 5.00
135 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2 5.00
136 INT291348 IL8 Positive_regulation of Phosphorylation of SHC1 1 0.11 1.16 0.2 5.00
137 INT291346 IL8 Positive_regulation of Binding of EGFR and GRB2 1 0.15 1.17 0.2 5.00
138 INT353808 HLA-DMA Regulation of HLA-B 1 0.00 1.72 0.19 5.00
139 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19 5.00
140 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
141 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
142 INT193214 Binding of PTGER2 and PTGER4 2 0.08 2.51 0.18 5.00
143 INT316477 Stat3 Positive_regulation of Il10 1 0.39 0.35 0.18 5.00
144 INT235441 HMBS Regulation of PPARA 1 0.03 0.76 0.16 5.00
145 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16 5.00
146 INT316484 Akt1 Positive_regulation of Positive_regulation of Stat3 1 0.01 0.87 0.16 5.00
147 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16 5.00
148 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16 5.00
149 INT189694 Negative_regulation of INSRR Negative_regulation of CHKB 1 0.00 0.07 0.15 5.00
150 INT316479 Il6 Positive_regulation of Snai1 1 0.24 0.33 0.15 5.00
151 INT316482 Il6 Positive_regulation of Cdh1 1 0.03 0.33 0.15 5.00
152 INT189695 INSRR Negative_regulation of CHKB 1 0.00 0.07 0.15 5.00
153 INT189647 INSRR Negative_regulation of CHKB Regulation of Negative_regulation of PRKCA 1 0.00 0.07 0.15 5.00
154 INT316490 Il6 Positive_regulation of Positive_regulation of Stat3 1 0.50 0.33 0.15 5.00
155 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14 5.00
156 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14 5.00
157 INT287890 THEMIS Regulation of Gene_expression of EPHB2 1 0.00 0.87 0.14 5.00
158 INT188249 PLAT Positive_regulation of PLG 2 0.10 0.86 0.14 5.00
159 INT287883 FOS Regulation of Gene_expression of EPHB2 1 0.01 0.87 0.14 5.00
160 INT291347 Positive_regulation of TXK Positive_regulation of CXCR4 Positive_regulation of EPHB2 1 0.02 0.61 0.13 5.00
161 INT175398 Binding of ERBB2 and VEGFA 2 0.16 1.34 0.13 5.00
162 INT175401 Binding of EGFR and VEGFA 2 0.13 1.49 0.13 5.00
163 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
164 INT302156 AKT1 Positive_regulation of E2F2 1 0.02 0.88 0.13 5.00
165 INT291349 CXCR4 Positive_regulation of EPHB2 1 0.42 1.87 0.13 5.00
166 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13 5.00
167 INT348542 BCL2 Negative_regulation of NLRP1 1 0.07 2.02 0.13 5.00
168 INT287878 Binding of CREB1 and CREBBP 2 0.01 0.16 0.12 5.00
169 INT287881 THEMIS Positive_regulation of PRKCA 1 0.00 0.07 0.12 5.00
170 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11 5.00
171 INT258527 Binding of BRAF and RET 1 0.21 1.49 0.11 5.00
172 INT302161 AKT1 Negative_regulation of CASP9 1 0.03 0.87 0.11 5.00
173 INT291353 IL8 Positive_regulation of Binding of EGFR 1 0.32 0.52 0.1 5.00
174 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 5.00
175 INT287893 VEGFA Positive_regulation of Localization of WISP1 1 0.03 1.23 0.1 5.00
176 INT191184 Binding of EGFR and GRB2 7 0.35 1.06 0.1 5.00
177 INT189702 CHKB Regulation of Gene_expression of TERT 1 0.06 0.55 0.1 5.00
178 INT302287 Twist1 Positive_regulation of Positive_regulation of PTGER2 1 0.03 1.16 0.1 5.00
179 INT302288 Twist1 Positive_regulation of PTGER2 1 0.03 1.16 0.1 5.00
180 INT291351 Binding of EGFR and SHC1 1 0.05 0.57 0.1 5.00
181 INT258522 Binding of DDR1 and RET 1 0.03 1.05 0.1 5.00
182 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1 5.00
183 INT291350 IL8 Positive_regulation of Phosphorylation of EGFR 1 0.32 0.52 0.1 5.00
184 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 5.00
185 INT291358 Binding of CXCL12 and CXCR7 1 0.20 0.11 0.09 5.00
186 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09 5.00
187 INT302167 PTGER2 Positive_regulation of EGFR 1 0.10 3.08 0.09 5.00
188 INT287886 Negative_regulation of THEMIS Negative_regulation of PRKCA 1 0.00 1.19 0.08 5.00
189 INT302178 CDKN1C Regulation of CDKN2A 1 0.09 0.26 0.08 5.00
190 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08 5.00
191 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08 5.00
192 INT287880 Binding of CREB1 and EP300 1 0.01 0 0.08 5.00
193 INT302139 LAMTOR1 Regulation of CDKN2A 1 0.08 0.26 0.08 5.00
194 INT302157 MRPL28 Regulation of CDKN2A 1 0.09 0.26 0.08 5.00
195 INT302148 IFI27 Regulation of CDKN2A 1 0.11 0.26 0.08 5.00
196 INT213933 AR Negative_regulation of Cyp19a1 1 0.07 0.79 0.07 5.00
197 INT302152 PTGER2 Positive_regulation of EMR1 1 0.01 2.02 0.07 5.00
198 INT335890 Binding of Dkk1 and Lrp4 1 0.37 0.64 0.07 5.00
199 INT335886 Binding of Sost and Lrp4 1 0.28 0.65 0.07 5.00
200 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cervical Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Cervical Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT244404 Binding of HEPACAM 21 0.02 35.88 0.09 100.00
2 INT23330 Binding of Chrna7 79 0.48 10.06 35.5 100.00
3 INT211679 Positive_regulation of HEPACAM 6 0.02 8.25 0.11 100.00
4 INT165886 Positive_regulation of Gene_expression of Bsp 1 0.43 1.23 0.09 100.00
5 INT165887 Gene_expression of Bsp 1 0.58 1.22 0.08 100.00
6 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 100.00
7 INT273406 Positive_regulation of Gene_expression of TWIST1 4 0.57 8.42 0.04 100.00
8 INT223899 Binding of Ifi35 3 0.36 5.98 0.13 100.00
9 INT113865 Binding of CXADR 35 0.46 3.18 1.12 100.00
10 INT231199 Positive_regulation of Localization of Twist1 3 0.50 1.45 0.38 100.00
11 INT302239 Positive_regulation of Gene_expression of BTG2 2 0.12 1.18 0.23 100.00
12 INT119102 Gene_expression of PDGFRA 13 0.75 11.99 0.81 99.98
13 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2 99.98
14 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1 99.92
15 INT4649 Positive_regulation of Chrna7 17 0.50 5.48 3.92 99.90
16 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 99.84
17 INT19396 Regulation of Rac1 66 0.53 37.41 30.01 99.84
18 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2 99.84
19 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22 99.84
20 INT91667 Localization of IL12A 39 0.74 25.51 7.36 99.84
21 INT197024 Binding of STIP1 11 0.35 10.84 0.52 99.84
22 INT335867 Positive_regulation of Negative_regulation of Sfrp2 1 0.14 0.49 0.03 99.84
23 INT348494 Negative_regulation of RBBP4 1 0.17 0.55 0 99.84
24 INT244405 Gene_expression of HPV6AI1 3 0.03 6.1 0.03 99.80
25 INT221792 Protein_catabolism of PDXP 1 0.06 1.37 0.32 99.80
26 INT200685 Negative_regulation of Gene_expression of AKT2 1 0.38 6.09 0 99.80
27 INT108203 Negative_regulation of Gene_expression of AKT1 28 0.54 16.38 3.19 99.80
28 INT147582 Negative_regulation of AIS 13 0.37 13.26 2.46 99.80
29 INT10873 Localization of Twist1 21 0.74 10.43 1.37 99.80
30 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4 99.72
31 INT48880 Positive_regulation of TWIST1 15 0.59 8.6 1.98 99.72
32 INT184532 Binding of SMUG1 7 0.21 5.73 1.45 99.72
33 INT235659 Gene_expression of EFNA1 1 0.45 22.92 0.06 99.70
34 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47 99.70
35 INT132969 Gene_expression of HPV18I1 4 0.27 10.84 0.05 99.68
36 INT351411 Gene_expression of Mfng 1 0.11 2.19 0.07 99.68
37 INT200675 Localization of AKT3 2 0.45 0.7 0.31 99.68
38 INT34904 Negative_regulation of Gtf3a 48 0.15 38.88 13.73 99.64
39 INT216867 Localization of PDXP 4 0.28 6.31 0.62 99.60
40 INT97126 Regulation of CASP3 9 0.40 8.15 3.6 99.60
41 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98 99.58
42 INT235654 Binding of EPHA2 5 0.36 4.26 0 99.56
43 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 99.56
44 INT235660 Gene_expression of EPHA2 27 0.75 23.46 0.4 99.52
45 INT193402 Gene_expression of UNC5B 5 0.27 1.82 0 99.48
46 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 99.42
47 INT200670 Gene_expression of AKT2 25 0.75 16.25 3 99.42
48 INT235655 Positive_regulation of Gene_expression of EPHA2 14 0.67 13.48 0.35 99.38
49 INT235656 Positive_regulation of Gene_expression of EFNA1 1 0.40 8.86 0 99.38
50 INT335871 Negative_regulation of Sfrp2 1 0.18 0.91 0.06 99.36
51 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 99.24
52 INT45168 Negative_regulation of ASAP1 23 0.58 10.15 2.44 99.22
53 INT137449 Positive_regulation of HEPN1 2 0.01 1.46 0.16 99.18
54 INT118286 Binding of EFNA1 3 0.21 4.95 1.55 99.16
55 INT223900 Gene_expression of Ifi35 6 0.65 10.52 0 99.16
56 INT133194 Negative_regulation of TERT 23 0.48 4.01 2.45 99.12
57 INT84685 Regulation of BCL2 67 0.60 72.96 6.65 99.04
58 INT74019 Regulation of TSC1 27 0.35 23.61 0.79 99.04
59 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 99.00
60 INT135556 Localization of AKT1 38 0.69 12.78 1.17 99.00
61 INT60585 Regulation of TP53 59 0.59 54.55 5.21 98.96
62 INT335860 Negative_regulation of Sfrp1 1 0.18 0.91 0.06 98.92
63 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 98.90
64 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 98.88
65 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 98.76
66 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 98.72
67 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53 98.72
68 INT20611 Gene_expression of Asap1 55 0.65 23.71 14.62 98.72
69 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 98.66
70 INT209948 Gene_expression of CLEC3B 3 0.78 11.51 0.6 98.60
71 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 98.56
72 INT263908 Positive_regulation of Gene_expression of SLN 1 0.16 1.4 0.12 98.56
73 INT263905 Gene_expression of SLN 33 0.63 23.21 0.74 98.56
74 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 98.56
75 INT191153 Negative_regulation of Negative_regulation of HDAC9 1 0.09 0.57 0.05 98.56
76 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32 98.48
77 INT61171 Gene_expression of S100A8 92 0.76 57.74 9.98 98.34
78 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 98.32
79 INT539 Negative_regulation of Chrna7 14 0.42 4.59 6.42 98.22
80 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07 98.20
81 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 98.20
82 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 98.20
83 INT348455 Binding of RBBP6 1 0.17 0.55 0 98.20
84 INT234676 Gene_expression of SNCG 4 0.78 63.59 0.08 98.12
85 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 98.04
86 INT95481 Regulation of Gene_expression of TRPV1 48 0.62 29.3 26.28 98.04
87 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 98.02
88 INT127863 Binding of PAR4 2 0.47 19.9 1.03 98.00
89 INT118791 Binding of AKT1 32 0.48 15.51 2.25 98.00
90 INT100046 Gene_expression of BTG2 16 0.20 10.81 1.95 98.00
91 INT204842 Positive_regulation of Cd44 9 0.49 6.6 0.77 98.00
92 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 97.92
93 INT244403 Regulation of Gene_expression of HPV6AI1 1 0.01 2.18 0 97.86
94 INT202230 Regulation of UNC5B 4 0.04 2.3 0.49 97.84
95 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03 97.80
96 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 97.80
97 INT14502 Gene_expression of BCHE 40 0.67 18.52 4.6 97.80
98 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 97.76
99 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 97.76
100 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 97.72
101 INT11230 Regulation of MUC16 23 0.60 19.54 3.93 97.68
102 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25 97.66
103 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 97.52
104 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42 97.48
105 INT23176 Gene_expression of Pdpn 6 0.75 4.06 1.65 97.44
106 INT84686 Regulation of BAX 26 0.49 28.54 4.13 97.44
107 INT97749 Regulation of BCL2L1 10 0.41 9.72 1.65 97.44
108 INT172227 Regulation of Localization of BAX 3 0.26 4.79 0.24 97.44
109 INT229235 Regulation of Localization of BCL2 2 0.29 3.7 0.15 97.44
110 INT124699 Regulation of Zbtb8b 1 0.03 0.1 0 97.44
111 INT144264 Gene_expression of KCNH1 6 0.65 17.69 2.83 97.40
112 INT43443 Binding of H3 11 0.19 2.9 2.38 97.40
113 INT191137 Binding of H47 4 0.19 1.22 0.13 97.40
114 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 97.40
115 INT191140 Negative_regulation of Binding of H47 1 0.06 0.56 0.05 97.40
116 INT191138 Negative_regulation of Binding of H3 2 0.06 0.56 0.05 97.40
117 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 97.36
118 INT68286 Regulation of SERPINB3 10 0.60 3.07 0.06 97.24
119 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 97.20
120 INT132997 Localization of Mmp9 59 0.80 45.9 17.61 97.20
121 INT161206 Negative_regulation of Localization of Mmp9 10 0.59 9.68 3.59 97.20
122 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74 97.12
123 INT231586 Gene_expression of SIPA1L1 2 0.03 2.24 0 97.10
124 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64 97.04
125 INT52713 Regulation of Negative_regulation of PRKCA 5 0.36 1.23 1.41 97.04
126 INT259062 Binding of HPV18I1 2 0.01 3.78 0.09 96.96
127 INT95120 Positive_regulation of CASP9 76 0.67 67.55 5.33 96.88
128 INT225167 Negative_regulation of Binding of RB1 2 0.34 1.25 0 96.84
129 INT111398 Localization of Mmp2 37 0.76 23.78 7.17 96.80
130 INT180923 Negative_regulation of Localization of Mmp2 6 0.46 7.84 2.17 96.80
131 INT77925 Negative_regulation of TEP1 21 0.53 15.23 2.62 96.68
132 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15 96.64
133 INT200739 Regulation of METTL1 1 0.01 1.03 0 96.60
134 INT200735 Regulation of NME1 1 0.60 1.03 0 96.60
135 INT111161 Positive_regulation of EFNA1 6 0.40 4.62 0.68 96.52
136 INT235658 Positive_regulation of EPHA2 4 0.67 3.42 0.32 96.52
137 INT351414 Gene_expression of Mipep 1 0.75 41.22 4.59 96.48
138 INT73476 Transcription of MYC 18 0.69 12.14 2.13 96.48
139 INT73475 Positive_regulation of Transcription of MYC 7 0.67 5.46 1.66 96.48
140 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 96.44
141 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43 96.44
142 INT3364 Binding of SGCG 87 0.47 31.93 17.24 96.40
143 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 96.40
144 INT15375 Gene_expression of AXL 21 0.65 18.5 3.74 96.40
145 INT131133 Binding of HMBS 9 0.36 2.13 0.19 96.40
146 INT124579 Localization of BAX 35 0.78 30.31 3.43 96.32
147 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7 96.32
148 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9 96.24
149 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 96.24
150 INT124314 Gene_expression of IGF2BP3 7 0.77 33.13 0.97 96.16
151 INT164756 Negative_regulation of PDGFRB 32 0.57 21.69 0.72 96.16
152 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58 96.12
153 INT21685 Gene_expression of ras 115 0.66 85.6 7.76 96.12
154 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63 96.12
155 INT169725 Binding of Il6ra 4 0.07 3.99 0.59 96.08
156 INT242321 Negative_regulation of Gene_expression of Asap1 1 0.20 1.96 0 96.08
157 INT8546 Positive_regulation of MUC16 99 0.69 74.98 11.26 96.04
158 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 96.04
159 INT9385 Localization of LDHA 74 0.81 31.67 10.5 96.04
160 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8 96.04
161 INT6699 Positive_regulation of ADRA1D 65 0.70 22.72 20.31 96.04
162 INT315130 Phosphorylation of PAR4 1 0.80 1.96 0 96.04
163 INT315104 Negative_regulation of Phosphorylation of PAR4 1 0.42 1.97 0 96.04
164 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26 96.00
165 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 96.00
166 INT70021 Localization of BCL2 23 0.74 21.6 1.09 95.92
167 INT180186 Localization of BCL2L1 2 0.33 3.86 0.24 95.92
168 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 95.88
169 INT200733 Gene_expression of METTL1 1 0.04 1.03 0 95.88
170 INT24199 Binding of Mrvi1 2 0.10 3.79 0.69 95.84
171 INT135042 Gene_expression of Tg(MMTV-Notch4)3Rnc 9 0.15 5.17 1.13 95.72
172 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 95.72
173 INT194993 Binding of RB1 15 0.37 10.96 0.4 95.72
174 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82 95.56
175 INT183689 Positive_regulation of Gene_expression of Cxcl1 21 0.58 9.13 5.5 95.56
176 INT54763 Binding of Il6 82 0.48 63.27 12.89 95.44
177 INT33857 Negative_regulation of NTS 6 0.42 4.98 3.07 95.44
178 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08 95.44
179 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 95.36
180 INT189766 Regulation of Transcription of TERT 1 0.25 3.48 1.99 95.36
181 INT70800 Negative_regulation of Positive_regulation of PRKCA 9 0.34 2.18 5.17 95.36
182 INT72216 Regulation of Positive_regulation of PRKCA 9 0.37 1.36 3.26 95.36
183 INT133195 Negative_regulation of Transcription of TERT 4 0.42 2.9 1.08 95.36
184 INT178053 Positive_regulation of STIP1 7 0.44 5.09 0.11 95.36
185 INT92941 Binding of ASAP1 24 0.39 12.38 1.25 95.28
186 INT136388 Gene_expression of Cxcl5 13 0.75 21.45 2.98 95.28
187 INT259059 Regulation of HPV18I1 3 0.00 5.16 0 95.28
188 INT34669 Localization of Hypism 8 0.25 10.79 1.2 95.28
189 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 95.20
190 INT8547 Gene_expression of MUC16 116 0.78 75.97 12.18 95.16
191 INT1352 Localization of Acot1 728 0.80 73.01 296.01 94.88
192 INT121494 Transcription of TERT 64 0.69 10.03 5.55 94.80
193 INT189770 Positive_regulation of Transcription of TERT 1 0.28 1.36 2.14 94.80
194 INT101857 Negative_regulation of BCL2L1 22 0.57 23.56 3.95 94.76
195 INT106382 Gene_expression of NME1 13 0.66 5.18 0.56 94.76
196 INT46877 Negative_regulation of CLEC3B 2 0.43 6.35 0.04 94.76
197 INT199320 Positive_regulation of MAPK8IP2 2 0.28 1.5 0.08 94.72
198 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 94.60
199 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 94.60
200 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 94.52
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