D:Choledocholithiasis

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pChart

Disease Term
Synonyms Cholelithiasis Common Bile Duct
Documents 240
Hot Single Events 29
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Choledocholithiasis. They are ordered first by their relevance to Choledocholithiasis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT167881 Ctrb1 Regulation of Gene_expression of PRSS2 1 0.10 1.81 0.26 81.32
2 INT167880 Pnliprp1 Regulation of Gene_expression of PRSS2 1 0.13 1.81 0.26 81.32
3 INT287794 Binding of IGHG3 and AIP 1 0.05 2.8 0.24 5.00
4 INT252646 Binding of C6orf25 and SYT16 1 0.00 0.51 0.17 5.00
5 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Choledocholithiasis. They are ordered first by their pain relevance and then by number of times they were reported in Choledocholithiasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT230 Positive_regulation of GGTLC1 14 0.68 11.78 1.55 100.00
2 INT12616 Positive_regulation of REG1A 23 0.69 6.57 5.81 99.16
3 INT39874 Positive_regulation of Reg1 12 0.68 5.41 3.8 99.16
4 INT178989 Regulation of CD200 2 0.34 0.63 0.16 99.16
5 INT57644 Regulation of SPINK1 7 0.47 15.19 3.64 98.76
6 INT99410 Positive_regulation of UGT1A1 10 0.45 2.2 2.07 93.68
7 INT20052 Negative_regulation of UGT1A1 12 0.58 4.51 4.29 92.60
8 INT340339 Negative_regulation of UGT1A 1 0.42 1.56 0.21 92.28
9 INT3851 Gene_expression of Got1 58 0.65 29.15 10.52 91.20
10 INT31340 Positive_regulation of Gene_expression of Got1 20 0.46 10.5 3.17 91.20
11 INT2723 Gene_expression of Salpa1 16 0.64 11.78 3.5 91.20
12 INT4027 Positive_regulation of Gene_expression of Salpa1 3 0.48 1.51 0.53 91.20
13 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 91.04
14 INT284 Positive_regulation of Ggt6 18 0.67 13.56 4.62 90.48
15 INT3970 Positive_regulation of Sord 9 0.70 4.29 3.93 90.48
16 INT39664 Regulation of Ggt6 4 0.26 2.97 1.13 90.48
17 INT39667 Positive_regulation of Positive_regulation of Sord 2 0.18 1.99 0.27 90.48
18 INT39665 Regulation of Sord 1 0.02 0.89 0.19 90.48
19 INT39666 Positive_regulation of Positive_regulation of Ggt6 1 0.08 0.9 0.19 90.48
20 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78 89.92
21 INT115515 Positive_regulation of PRSS2 5 0.69 5.76 1.13 89.60
22 INT167877 Gene_expression of Pnliprp1 1 0.39 1.92 0.29 88.00
23 INT167876 Transcription of Cela3b 1 0.40 3.87 0.57 86.24
24 INT13803 Gene_expression of Panc2 8 0.07 10.41 1.98 84.52
25 INT167873 Transcription of Ctrb1 1 0.23 1.92 0.28 84.20
26 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 83.84
27 INT66258 Negative_regulation of Positive_regulation of Salpa1 2 0.16 0.5 0.6 83.84
28 INT136720 Gene_expression of PRSS2 6 0.50 4.99 1.43 81.32
29 INT167879 Negative_regulation of Gene_expression of PRSS2 1 0.21 1.8 0.26 81.32
30 INT193438 Binding of MCO 1 0.39 1.77 0.06 79.40
31 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 78.80
32 INT126457 Gene_expression of BCL6 34 0.66 22.45 1.75 78.56
33 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 78.28
34 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34 77.20
35 INT92386 Gene_expression of Tnfrsf8 14 0.54 13.55 1.67 77.20
36 INT66852 Gene_expression of Fcer2 15 0.14 9.74 1.27 77.20
37 INT120062 Binding of AIP 4 0.42 28.86 3.91 76.72
38 INT213689 Binding of HPYR1 4 0.29 4.69 0.41 76.32
39 INT37335 Gene_expression of Nsdhl 45 0.51 24.36 4.58 74.20
40 INT167875 Gene_expression of Cela3b 1 0.43 2.79 0.36 73.96
41 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 69.92
42 INT288302 Positive_regulation of Phosphorylation of SLC17A5 1 0.49 2 0.24 69.92
43 INT288301 Phosphorylation of SLC17A5 1 0.79 1.8 0.23 69.92
44 INT55093 Negative_regulation of SPINK1 13 0.42 15.11 3.8 68.24
45 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 67.20
46 INT288300 Positive_regulation of Phosphorylation of GGT1 1 0.49 1.94 0.21 67.20
47 INT288303 Phosphorylation of GGT1 1 0.79 1.74 0.2 67.20
48 INT87573 Phosphorylation of Crp 2 0.05 1.99 0.21 64.40
49 INT288297 Positive_regulation of Phosphorylation of Crp 1 0.03 1.93 0.21 64.40
50 INT167878 Positive_regulation of Gene_expression of PRSS2 1 0.25 1.11 0.06 62.92
51 INT167874 Positive_regulation of Cela3b 1 0.28 1 0.06 61.40
52 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 59.28
53 INT193440 Positive_regulation of MCO 4 0.45 1.22 0 43.08
54 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 30.68
55 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 29.92
56 INT22080 Regulation of ras 40 0.53 36.24 4.44 25.00
57 INT4003 Positive_regulation of Gene_expression of IGHG3 31 0.46 20.38 3.16 8.32
58 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
59 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
60 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
61 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 5.00
62 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 5.00
63 INT12243 Positive_regulation of PRSS1 91 0.70 52.87 19.48 5.00
64 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
65 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 5.00
66 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 5.00
67 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 5.00
68 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
69 INT49266 Positive_regulation of Arigg4 37 0.47 53.79 11.2 5.00
70 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89 5.00
71 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 5.00
72 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 5.00
73 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 5.00
74 INT25022 Binding of PAEP 66 0.42 22.83 6.59 5.00
75 INT57720 Localization of IGHG3 33 0.74 20.24 6.25 5.00
76 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56 5.00
77 INT121801 Binding of Aip 18 0.36 24.1 5.26 5.00
78 INT105114 Gene_expression of Arigg4 16 0.52 21.88 4.56 5.00
79 INT112989 Gene_expression of AIP 3 0.56 25.4 4.23 5.00
80 INT148671 Gene_expression of Aip 26 0.63 24.32 3.91 5.00
81 INT149259 Gene_expression of RCT 38 0.67 15.73 3.87 5.00
82 INT3564 Positive_regulation of Aip 11 0.58 15.38 3.62 5.00
83 INT9854 Localization of GGT1 11 0.78 6.09 3.57 5.00
84 INT52021 Regulation of IGHG3 34 0.39 22.43 3.3 5.00
85 INT1153 Negative_regulation of FUT3 17 0.38 8.61 2.21 5.00
86 INT67190 Gene_expression of Muc2 24 0.78 18.8 2.08 5.00
87 INT121800 Positive_regulation of Gene_expression of Arigg4 7 0.31 10.86 2.02 5.00
88 INT18007 Positive_regulation of C6orf25 23 0.66 14.98 1.95 5.00
89 INT21999 Regulation of Gene_expression of IGHG3 8 0.30 3.26 1.84 5.00
90 INT41314 Gene_expression of GGTLC1 9 0.59 5.61 1.79 5.00
91 INT107985 Gene_expression of MLH1 29 0.67 31.31 1.46 5.00
92 INT83891 Gene_expression of FUT3 20 0.61 10.49 1.41 5.00
93 INT287798 Localization of AIP 1 0.63 5.96 1.31 5.00
94 INT114091 Negative_regulation of Aip 6 0.48 4.16 1.3 5.00
95 INT163592 Localization of CISH 5 0.54 5.9 1.26 5.00
96 INT287799 Positive_regulation of Gene_expression of AIP 1 0.42 7.39 1.19 5.00
97 INT85831 Positive_regulation of CA9 5 0.60 8.29 1.02 5.00
98 INT133102 Negative_regulation of Gene_expression of COL1A2 8 0.08 2.56 1.02 5.00
99 INT274238 Positive_regulation of AIP 2 0.42 8.14 0.97 5.00
100 INT153329 Gene_expression of Cm9 6 0.67 4.35 0.95 5.00
101 INT4436 Gene_expression of ABCB7 7 0.65 9.26 0.93 5.00
102 INT67191 Gene_expression of Muc3 11 0.29 9.93 0.91 5.00
103 INT193334 Gene_expression of HPYR1 11 0.53 10.36 0.88 5.00
104 INT211272 Positive_regulation of Igh-VS107 8 0.37 5.79 0.7 5.00
105 INT251026 Negative_regulation of Phosphorylation of CDKN2A 5 0.42 5.02 0.62 5.00
106 INT174271 Binding of F3 6 0.15 6.85 0.53 5.00
107 INT154449 Positive_regulation of Gene_expression of Aip 2 0.43 2.88 0.52 5.00
108 INT158440 Negative_regulation of Nsdhl 4 0.21 3.22 0.51 5.00
109 INT252662 Binding of SYT16 1 0.01 8.05 0.45 5.00
110 INT252658 Negative_regulation of Phosphorylation of ABCB7 1 0.41 2.93 0.45 5.00
111 INT252657 Positive_regulation of Phosphorylation of CDKN2A 2 0.45 3.09 0.42 5.00
112 INT88952 Gene_expression of Sic 4 0.58 0.81 0.42 5.00
113 INT7979 Binding of Nsdhl 6 0.30 3.71 0.4 5.00
114 INT144179 Localization of Aip 4 0.61 2.59 0.33 5.00
115 INT287795 Localization of FAM190B 1 0.05 2.71 0.33 5.00
116 INT251025 Phosphorylation of CDKN2A 4 0.61 3.19 0.32 5.00
117 INT174272 Negative_regulation of Gene_expression of F3 5 0.14 4.06 0.31 5.00
118 INT252661 Positive_regulation of Gene_expression of ABCB7 2 0.49 1.55 0.31 5.00
119 INT287800 Positive_regulation of Positive_regulation of AIP 1 0.42 2.15 0.3 5.00
120 INT252660 Positive_regulation of Phosphorylation of ABCB7 1 0.49 1.94 0.3 5.00
121 INT252656 Positive_regulation of Binding of F3 1 0.07 1.89 0.29 5.00
122 INT107643 Positive_regulation of Positive_regulation of Arigg4 2 0.02 1.72 0.25 5.00
123 INT356135 Positive_regulation of Binding of Aip 1 0.09 0.81 0.24 5.00
124 INT356136 Negative_regulation of Localization of Aip 1 0.08 0.88 0.23 5.00
125 INT64224 Localization of FUT3 3 0.06 3.16 0.2 5.00
126 INT272794 Positive_regulation of Positive_regulation of IGHG3 3 0.04 2.84 0.17 5.00
127 INT214692 Negative_regulation of Gene_expression of FUT3 3 0.24 2.2 0.17 5.00
128 INT19706 Binding of Arigg4 2 0.02 1.76 0.16 5.00
129 INT287797 Phosphorylation of AIP 1 0.78 2.04 0.16 5.00
130 INT252659 Phosphorylation of ABCB7 1 0.79 0.97 0.15 5.00
131 INT345973 Binding of EVL 1 0.07 1.4 0.14 5.00
132 INT345972 Binding of HGD 1 0.02 1.95 0.08 5.00
133 INT193439 Localization of MCO 1 0.61 0.49 0.08 5.00
134 INT287796 Regulation of Positive_regulation of IGHG3 1 0.02 1.19 0.03 5.00
135 INT322916 Negative_regulation of HTA 1 0.29 1.77 0 5.00
136 INT193437 Negative_regulation of MCO 4 0.48 0.68 0 5.00
137 INT322917 Negative_regulation of Negative_regulation of HTA 1 0.21 0.88 0 5.00
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