D:Choriocarcinoma

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Disease Term
Synonyms CHORIOCARCINOMAS
Documents 15
Hot Single Events 14
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Choriocarcinoma. They are ordered first by their relevance to Choriocarcinoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT350106 Binding of SLC4A3 and SLC4A1 1 0.13 2.78 0.09 96.64
2 INT252895 PTTG1 Regulation of Gene_expression of VEGFA 1 0.03 0.15 0 13.48
3 INT252902 PTTG1 Regulation of MMP2 1 0.01 1.5 0.14 5.00
4 INT253009 Igf1 Regulation of PTTG1 1 0.03 0.44 0.13 5.00
5 INT253015 Egf Regulation of PTTG1 1 0.02 0.44 0.13 5.00
6 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13 5.00
7 INT253023 Binding of PTTG1 and Myc 1 0.16 0.22 0.04 5.00
8 INT252897 Binding of PTTG1IP and PTTG1 1 0.04 0.15 0.04 5.00
9 INT252892 PTTG1IP Regulation of PTTG1 1 0.05 0.49 0.04 5.00
10 INT253017 PTTG1IP Regulation of Regulation of Fgf2 1 0.03 0.49 0.04 5.00
11 INT253010 Binding of PTTG1 and Fgf2 1 0.07 0.51 0.03 5.00
12 INT253003 Pttg1 Regulation of Gene_expression of Id3 1 0.08 0.07 0 5.00
13 INT253004 Anapc1 Positive_regulation of Binding of Pttg1 1 0.47 0 0 5.00
14 INT252910 PTTG1 Negative_regulation of Transcription of SLC5A5 1 0.02 0.36 0 5.00
15 INT253011 Negative_regulation of Binding of PTTG1 and Zic2 1 0.01 0.41 0 5.00
16 INT252886 PTTG1IP Positive_regulation of Binding of SLC5A5 and USF1 1 0.00 0.22 0 5.00
17 INT252887 PTTG1IP Positive_regulation of Binding of SLC5A5 and PAX8 1 0.01 0.22 0 5.00
18 INT252898 Binding of SLC5A5 and USF1 1 0.01 0.22 0 5.00
19 INT253021 PTTG1 Regulation of Gene_expression of Fgf2 1 0.04 0.35 0 5.00
20 INT252906 Binding of SLC5A5 and PTTG1 1 0.01 0.69 0 5.00
21 INT253007 Igf1 Regulation of Gene_expression of PTTG1 1 0.03 0.46 0 5.00
22 INT252889 Binding of PTTG2 and PTTG3P 1 0.06 0.08 0 5.00
23 INT253018 Binding of PTTG1 and Zic2 1 0.01 0.76 0 5.00
24 INT252888 Binding of SLC5A5 and PAX8 1 0.02 0.22 0 5.00
25 INT252905 PTTG1IP Negative_regulation of Transcription of SLC5A5 1 0.01 0.35 0 5.00
26 INT253014 Binding of XRCC5 and Zic2 1 0.00 0.14 0 5.00
27 INT253008 PTTG1 Regulation of Gene_expression of Id3 1 0.03 0.2 0 5.00
28 INT252900 PTTG1 Regulation of Gene_expression of TAF9 1 0.20 0.84 0 5.00
29 INT253020 Pttg1 Negative_regulation of THBS1 1 0.03 0.16 0 5.00
30 INT253019 APC Positive_regulation of Protein_catabolism of Pttg1 1 0.06 0 0 5.00
31 INT253012 APC Positive_regulation of Binding of Pttg1 1 0.06 0 0 5.00
32 INT253016 Binding of PTTG1 and Id3 1 0.04 0.07 0 5.00
33 INT252896 INS Regulation of Gene_expression of PTTG1 1 0.00 0.47 0 5.00
34 INT252904 Binding of PRKDC and XRCC5 1 0.00 0.14 0 5.00
35 INT253013 Binding of PRKDC and Zic2 1 0.00 0.14 0 5.00
36 INT252907 Binding of PTTG1 and PTTG2 1 0.07 0.08 0 5.00
37 INT252893 PTTG1 Positive_regulation of Gene_expression of TAF9 1 0.21 0.9 0 5.00
38 INT253005 Binding of Zic2 and Pttg1 1 0.02 0.57 0 5.00
39 INT252903 PTTG1IP Regulation of Gene_expression of SLC5A5 1 0.00 0.43 0 5.00
40 INT252908 Binding of PTTG3P and GOPC 1 0.01 0.08 0 5.00
41 INT252899 PTTG1 Regulation of Gene_expression of SLC5A5 1 0.01 0.43 0 5.00
42 INT253022 PTTG1 Negative_regulation of Negative_regulation of Trp53 1 0.03 1.34 0 5.00
43 INT252890 PTTG1IP Negative_regulation of SLC5A5 1 0.01 0.34 0 5.00
44 INT253006 Anapc1 Positive_regulation of Protein_catabolism of Pttg1 1 0.51 0 0 5.00
45 INT252909 FZR1 Positive_regulation of APC 1 0.06 0.08 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Choriocarcinoma. They are ordered first by their pain relevance and then by number of times they were reported in Choriocarcinoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 99.92
2 INT200108 Binding of CGB 2 0.11 1.22 0 97.12
3 INT15837 Binding of CGA 31 0.41 12.06 3.17 94.00
4 INT200107 Gene_expression of SDHA 9 0.37 5.29 1.02 92.16
5 INT76735 Positive_regulation of CGB7 3 0.38 2.91 0.28 90.80
6 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 90.72
7 INT76732 Gene_expression of CGB7 4 0.63 4.14 0.37 90.44
8 INT8546 Positive_regulation of MUC16 99 0.69 74.98 11.26 89.72
9 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 89.72
10 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87 86.48
11 INT252975 Positive_regulation of Gene_expression of PTTG1 36 0.28 31.96 0.74 86.48
12 INT172678 Gene_expression of NUPL2 20 0.75 5.06 2.85 81.56
13 INT178962 Gene_expression of Oca2 15 0.19 5.15 0.38 80.60
14 INT252954 Positive_regulation of Gene_expression of Oca2 2 0.03 2.21 0 80.60
15 INT76733 Negative_regulation of Gene_expression of CGB7 1 0.05 1.33 0.08 75.76
16 INT62331 Gene_expression of TNFRSF8 26 0.72 17.75 2.08 75.40
17 INT7035 Regulation of CGA 87 0.45 29.04 28.45 75.00
18 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 75.00
19 INT4953 Positive_regulation of CGB5 16 0.60 7.63 2.49 75.00
20 INT104751 Positive_regulation of Gene_expression of CGB5 2 0.40 1.55 0.19 75.00
21 INT15635 Gene_expression of CGB5 4 0.59 2.38 0.44 75.00
22 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 75.00
23 INT76734 Negative_regulation of CGB7 1 0.05 1.32 0.08 74.48
24 INT8547 Gene_expression of MUC16 116 0.78 75.97 12.18 73.36
25 INT189948 Gene_expression of Pttg1 106 0.76 104.68 1.41 65.56
26 INT189946 Positive_regulation of Gene_expression of Pttg1 14 0.68 23.72 0.38 65.56
27 INT1792 Positive_regulation of CGA 123 0.70 64.73 20.79 61.48
28 INT154527 Gene_expression of POU5F1 180 0.78 34.01 4.34 57.04
29 INT200109 Positive_regulation of Gene_expression of NUPL2 1 0.49 0.44 0.1 50.00
30 INT252977 Positive_regulation of PTTG1 1 0.28 8.39 0.18 49.96
31 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 44.32
32 INT115982 Positive_regulation of KRT7 18 0.50 19.81 1.14 44.32
33 INT38673 Negative_regulation of KRT20 38 0.42 22.49 2.77 40.84
34 INT92679 Positive_regulation of Fgf2 13 0.69 11.43 5.18 29.80
35 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 12.04
36 INT11728 Binding of NUPL2 3 0.47 3.28 0.42 7.96
37 INT70449 Binding of SLC4A1 5 0.36 5.1 0.38 7.16
38 INT129621 Gene_expression of Id3 5 0.75 2.3 0.36 6.92
39 INT283503 Binding of SLC4A2 3 0.09 3.39 0.19 6.36
40 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 5.00
41 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 5.00
42 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26 5.00
43 INT847 Regulation of Lhb 131 0.61 22.08 46.54 5.00
44 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
45 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
46 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
47 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 5.00
48 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
49 INT2261 Gene_expression of Lhb 121 0.77 42.78 26.04 5.00
50 INT34487 Localization of MMP2 56 0.81 31.41 23.61 5.00
51 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 5.00
52 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95 5.00
53 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 5.00
54 INT85639 Positive_regulation of Tg(CAG-EGFP)D4Nagy 95 0.43 24.83 15.69 5.00
55 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 5.00
56 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18 5.00
57 INT92680 Gene_expression of Fgf2 59 0.77 28.11 8.12 5.00
58 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 5.00
59 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86 5.00
60 INT67568 Positive_regulation of Localization of MMP2 14 0.31 8.58 6.79 5.00
61 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24 5.00
62 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08 5.00
63 INT178754 Positive_regulation of Localization of GOPC 32 0.43 10.1 4.73 5.00
64 INT17182 Binding of Cea 25 0.48 14.98 4.16 5.00
65 INT16235 Positive_regulation of CGB 27 0.70 15.71 4.06 5.00
66 INT252968 Positive_regulation of TAF9 11 0.45 5.28 3.68 5.00
67 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68 5.00
68 INT4771 Gene_expression of CGB 23 0.67 14.22 3.42 5.00
69 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 5.00
70 INT252999 Gene_expression of TAF9 12 0.75 12.65 2.92 5.00
71 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45 5.00
72 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3 5.00
73 INT9119 Negative_regulation of TAF9 4 0.42 5.21 2.16 5.00
74 INT5129 Regulation of Gene_expression of Lhb 10 0.55 4.79 2.09 5.00
75 INT87436 Regulation of Fgf2 6 0.45 3.95 2.03 5.00
76 INT60337 Positive_regulation of THBS1 8 0.46 4.69 1.83 5.00
77 INT172961 Localization of Egf 26 0.71 16.74 1.81 5.00
78 INT109967 Gene_expression of Mmv7 21 0.35 15.66 1.7 5.00
79 INT92677 Positive_regulation of Gene_expression of Fgf2 11 0.69 4.25 1.68 5.00
80 INT64233 Regulation of Trp53 35 0.62 27.11 1.53 5.00
81 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41 5.00
82 INT169907 Gene_expression of Rb1 25 0.60 21.95 1.32 5.00
83 INT174156 Localization of Trp53 16 0.72 13.52 1.18 5.00
84 INT122813 Binding of Krt20 11 0.32 13.77 0.88 5.00
85 INT178498 Negative_regulation of Fgf2 11 0.42 4.21 0.84 5.00
86 INT124850 Gene_expression of Tpt1 42 0.77 14.51 0.79 5.00
87 INT169911 Phosphorylation of Rb1 35 0.73 18.58 0.79 5.00
88 INT252993 Negative_regulation of THBS1 8 0.55 6.93 0.59 5.00
89 INT3557 Positive_regulation of C1S 10 0.67 8.73 0.54 5.00
90 INT176264 Binding of PCNA 21 0.21 9.08 0.51 5.00
91 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42 5.00
92 INT196916 Negative_regulation of Rb1 13 0.42 14.29 0.4 5.00
93 INT252989 Localization of PTTG1 1 0.32 1.49 0.36 5.00
94 INT252961 Localization of Fgf1 3 0.27 5.91 0.35 5.00
95 INT101902 Negative_regulation of Mki67 12 0.39 7.92 0.34 5.00
96 INT252969 Positive_regulation of Gene_expression of TAF9 5 0.67 5.22 0.32 5.00
97 INT189953 Regulation of PTTG1 2 0.18 6.45 0.25 5.00
98 INT252951 Localization of Oca2 2 0.17 1.53 0.23 5.00
99 INT64674 Regulation of PTTG1IP 3 0.24 0.48 0.21 5.00
100 INT97578 Regulation of FSHB 3 0.26 1.41 0.17 5.00
101 INT252998 Gene_expression of PTTG1IP 1 0.17 2.06 0.17 5.00
102 INT189945 Localization of Pttg1 3 0.73 3.02 0.16 5.00
103 INT73080 Positive_regulation of TTF1 4 0.38 2.37 0.14 5.00
104 INT10452 Positive_regulation of PTTG1IP 2 0.41 0.6 0.1 5.00
105 INT252971 Positive_regulation of Gene_expression of PTTG1IP 1 0.11 1.37 0.09 5.00
106 INT239095 Negative_regulation of PTTG1 2 0.32 8.24 0.09 5.00
107 INT252991 Regulation of TAF9 2 0.44 3.54 0.08 5.00
108 INT252962 Localization of Dld 1 0.02 0.31 0.08 5.00
109 INT129609 Regulation of Gene_expression of Id3 1 0.44 0.3 0.06 5.00
110 INT195679 Positive_regulation of Positive_regulation of APC 6 0.50 4.43 0.05 5.00
111 INT252994 Binding of PTTG1IP 1 0.09 0.67 0.04 5.00
112 INT252992 Regulation of Gene_expression of PTTG1 1 0.18 5.07 0.04 5.00
113 INT252980 Binding of PTTG1 1 0.19 0.59 0.04 5.00
114 INT252208 Gene_expression of Slc5a5 2 0.14 0.87 0.04 5.00
115 INT236701 Negative_regulation of Gene_expression of Rb1 4 0.10 4.55 0.03 5.00
116 INT252965 Positive_regulation of Transcription of PTTG1IP 1 0.10 0.53 0.03 5.00
117 INT252959 Binding of Zic2 3 0.37 0.37 0.03 5.00
118 INT252966 Negative_regulation of Gene_expression of PTTG1 1 0.23 2.7 0.03 5.00
119 INT252950 Negative_regulation of Cd34 3 0.42 2.14 0.03 5.00
120 INT252982 Positive_regulation of Binding of PTTG1IP 1 0.10 0.52 0.03 5.00
121 INT201049 Negative_regulation of SLC5A5 5 0.05 2.25 0.03 5.00
122 INT252979 Positive_regulation of Localization of PTTG1 1 0.20 0.18 0.03 5.00
123 INT252985 Transcription of SLC5A5 1 0.05 0.35 0 5.00
124 INT253000 Negative_regulation of Binding of NFYA 1 0.01 0.34 0 5.00
125 INT252948 Positive_regulation of Protein_catabolism of Pttg1 1 0.63 0.09 0 5.00
126 INT252949 Negative_regulation of Negative_regulation of Pttg1 1 0.39 0.34 0 5.00
127 INT299486 Localization of Krt20 2 0.19 1.49 0 5.00
128 INT252942 Phosphorylation of Chek1 1 0.14 0.63 0 5.00
129 INT252967 Localization of PTTG2 1 0.34 0.1 0 5.00
130 INT201053 Positive_regulation of Gene_expression of SLC5A5 3 0.06 1.18 0 5.00
131 INT252974 Positive_regulation of Negative_regulation of THBS1 1 0.03 0.09 0 5.00
132 INT252995 Gene_expression of PTTG2 1 0.33 0.1 0 5.00
133 INT252987 Positive_regulation of SLC5A5 1 0.03 0.35 0 5.00
134 INT252952 Protein_catabolism of Pttg1 1 0.91 0.09 0 5.00
135 INT189952 Transcription of PTTG1 2 0.21 1.6 0 5.00
136 INT189944 Negative_regulation of Gene_expression of Pttg1 4 0.42 4.53 0 5.00
137 INT252944 Positive_regulation of Pttg1 1 0.46 2.53 0 5.00
138 INT252938 Phosphorylation of Pttg1 1 0.75 1.11 0 5.00
139 INT252972 Negative_regulation of Gene_expression of PTTG2 1 0.18 0.1 0 5.00
140 INT252976 Transcription of PTTG1IP 1 0.13 0.53 0 5.00
141 INT252970 Negative_regulation of Positive_regulation of THBS1 1 0.04 0.2 0 5.00
142 INT252957 Regulation of Binding of Pttg1 1 0.41 0.64 0 5.00
143 INT189951 Binding of Pttg1 2 0.44 1.16 0 5.00
144 INT252958 Positive_regulation of Localization of Pttg1 1 0.37 0 0 5.00
145 INT201052 Negative_regulation of Gene_expression of SLC5A5 2 0.07 0.55 0 5.00
146 INT252978 Gene_expression of PTTG3P 1 0.28 0.09 0 5.00
147 INT252956 Negative_regulation of Gene_expression of Slc5a5 1 0.06 0.38 0 5.00
148 INT252960 Regulation of Regulation of Amhr2 1 0.03 1.35 0 5.00
149 INT189947 Regulation of Pttg1 4 0.49 7.18 0 5.00
150 INT182428 Binding of NFYA 2 0.02 0.43 0 5.00
151 INT252941 Regulation of Amhr2 1 0.08 1.35 0 5.00
152 INT252984 Regulation of Gene_expression of TAF9 1 0.26 0.99 0 5.00
153 INT252946 Negative_regulation of Binding of Pttg1 1 0.34 0.29 0 5.00
154 INT201051 Gene_expression of SLC5A5 6 0.09 2.08 0 5.00
155 INT252955 Positive_regulation of Negative_regulation of Pttg1 1 0.40 1.1 0 5.00
156 INT252988 Negative_regulation of Binding of PCNA 1 0.06 1.25 0 5.00
157 INT169921 Negative_regulation of Gene_expression of Tpt1 3 0.25 1.38 0 5.00
158 INT252945 Negative_regulation of Espl1 1 0.06 0 0 5.00
159 INT189943 Negative_regulation of Pttg1 2 0.53 5.8 0 5.00
160 INT252986 Regulation of Transcription of PTTG1 1 0.11 0.42 0 5.00
161 INT252983 Negative_regulation of Positive_regulation of PTTG1 1 0.17 0.89 0 5.00
162 INT252990 Phosphorylation of PTTG1 1 0.33 0.35 0 5.00
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