D:Choristoma

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Disease Term
Synonyms Aberrant Tissue, ABERRANT TISSUES, CHORISTOMAS, Ectopic Tissue, ECTOPIC TISSUES, HETEROTOPIC TISSUE, HETEROTOPIC TISSUES, Tissue Aberrant, TISSUE ECTOPIC, Tissue Heterotopic, Tissues Aberrant
Documents 58
Hot Single Events 34
Hot Interactions 6

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Choristoma. They are ordered first by their relevance to Choristoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08 98.44
2 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16 98.44
3 INT266803 Dlst Positive_regulation of VEGFA 1 0.01 0.96 0.25 96.60
4 INT266802 Dlst Positive_regulation of CCL5 1 0.00 0.95 0.25 96.60
5 INT266801 Dlst Positive_regulation of IL8 1 0.00 0.95 0.25 96.60
6 INT266771 Binding of NGF and GOPC 1 0.05 3.23 1.43 90.20
7 INT266806 Hand2 Regulation of Gene_expression of IL10 1 0.00 1.23 0.32 29.72
8 INT266804 Hand2 Regulation of Gene_expression of IL13 1 0.00 1.23 0.32 29.72
9 INT266805 Hand2 Regulation of Gene_expression of IL4 1 0.00 1.23 0.32 29.72
10 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85 5.00
11 INT229394 TPSD1 Positive_regulation of F2RL1 2 0.00 3.11 2.14 5.00
12 INT266764 TPSD1 Positive_regulation of F2RL1 Positive_regulation of Localization of SFTPA1 1 0.00 1.55 1.76 5.00
13 INT266768 NGF Positive_regulation of Localization of SFTPA1 1 0.01 1.65 1.6 5.00
14 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59 5.00
15 INT266769 IL2 Positive_regulation of Localization of IL4 1 0.00 1.03 0.72 5.00
16 INT266765 IL2 Positive_regulation of Localization of IL10 1 0.01 1.03 0.72 5.00
17 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66 5.00
18 INT208571 CCL21 Positive_regulation of Gene_expression of CCL16 1 0.51 0.63 0.38 5.00
19 INT266800 Dlst Positive_regulation of Localization of VEGFA 1 0.02 0.88 0.29 5.00
20 INT266766 Binding of PGR and GOPC 1 0.00 1.08 0.29 5.00
21 INT171050 Negative_regulation of F13A1 Regulation of PLG 1 0.02 0.55 0.28 5.00
22 INT171048 F13A1 Regulation of PLG 1 0.02 0.55 0.27 5.00
23 INT239087 Binding of SST and Negative_regulation of Localization of GH1 1 0.19 0.36 0.24 5.00
24 INT171049 Binding of FAS and Positive_regulation of Gene_expression of CASP3 1 0.04 1.41 0.24 5.00
25 INT73076 IGF1 Positive_regulation of GH1 4 0.45 0.99 0.15 5.00
26 INT207551 IGF1 Positive_regulation of Gene_expression of GH1 2 0.22 1.18 0.11 5.00
27 INT220149 Binding of IGF1 and IGFALS 2 0.39 0.44 0.1 5.00
28 INT173660 Map2k6 Positive_regulation of MAPK8 1 0.15 0.27 0.07 5.00
29 INT173659 Map2k3 Positive_regulation of MAPK8 1 0.15 0.28 0.07 5.00
30 INT173612 FGFR1 Positive_regulation of INCENP 1 0.00 0.28 0.03 5.00
31 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03 5.00
32 INT278495 IGFBP2 Positive_regulation of Gene_expression of IGF1 1 0.20 0 0 5.00
33 INT278498 IGFBP3 Regulation of GH1 1 0.06 0 0 5.00
34 INT278494 IGFBP3 Positive_regulation of Binding of IGF1 and IGFBP3 1 0.17 0 0 5.00
35 INT278499 IGFALS Regulation of GH1 1 0.18 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Choristoma. They are ordered first by their pain relevance and then by number of times they were reported in Choristoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 100.00
2 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 100.00
3 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 100.00
4 INT104979 Gene_expression of MITF 51 0.62 54.83 6.91 99.68
5 INT438 Gene_expression of Crh 376 0.78 159.11 169.17 99.34
6 INT249 Localization of GHRH 215 0.80 78.02 51.87 98.90
7 INT208590 Positive_regulation of Gene_expression of CYR61 1 0.36 1.28 0.44 98.64
8 INT201861 Gene_expression of CYR61 6 0.59 4.5 1.05 98.64
9 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 98.28
10 INT208592 Binding of CXCR1 3 0.36 2.26 1.32 98.20
11 INT208588 Binding of CXCR2 11 0.48 6.43 2.68 98.20
12 INT62958 Positive_regulation of CXCR2 14 0.59 8.61 4.92 97.72
13 INT97640 Positive_regulation of CXCR1 5 0.49 3.77 2.17 97.32
14 INT300946 Gene_expression of MIR202 1 0.17 0.27 0 97.20
15 INT300942 Positive_regulation of Gene_expression of MIR202 1 0.13 0.27 0 97.20
16 INT1562 Localization of Crh 499 0.81 126.74 236.68 96.60
17 INT252 Localization of GH1 529 0.80 227.4 122.05 96.28
18 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67 94.24
19 INT173533 Regulation of Gene_expression of CCL16 5 0.51 3.63 2.63 93.68
20 INT109910 Gene_expression of CCL16 104 0.74 76.1 43.97 93.00
21 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 90.68
22 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 90.68
23 INT71150 Binding of NGF 22 0.46 13.67 14.81 90.20
24 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 89.20
25 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 87.28
26 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 86.96
27 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31 85.80
28 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 85.36
29 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81 84.00
30 INT58591 Negative_regulation of Positive_regulation of PLG 4 0.42 2.46 0.51 84.00
31 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 82.64
32 INT21582 Regulation of Gene_expression of TIMP1 20 0.61 12.39 4.77 82.12
33 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 81.36
34 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 80.40
35 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 79.92
36 INT182229 Positive_regulation of CCL16 15 0.66 12.19 8.21 79.64
37 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 79.60
38 INT26585 Gene_expression of Vim 117 0.77 39.97 6 79.12
39 INT234494 Positive_regulation of Syp 12 0.65 2.47 0.69 78.08
40 INT57339 Negative_regulation of HLA-DRA 17 0.49 7.67 1.96 76.56
41 INT62430 Negative_regulation of HLA-A 5 0.32 4.3 1.63 76.56
42 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 76.16
43 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 76.16
44 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 76.16
45 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86 76.16
46 INT93144 Gene_expression of CCR1 18 0.75 14.69 6.84 74.08
47 INT112126 Positive_regulation of Gast 7 0.55 4.06 0.38 73.84
48 INT97638 Localization of CCL16 11 0.66 4.89 3.74 69.12
49 INT97642 Positive_regulation of Localization of CCL16 2 0.42 1 0.98 69.12
50 INT443 Localization of POMC 1020 0.81 284.52 443.17 68.44
51 INT109917 Positive_regulation of Gene_expression of CCL16 17 0.66 11.87 2.94 68.40
52 INT73223 Gene_expression of UPF1 78 0.41 31.44 9.94 64.96
53 INT48720 Transcription of SERPINE1 11 0.68 4.76 1.67 64.96
54 INT87495 Positive_regulation of Gene_expression of CCL5 26 0.69 13.85 9.46 63.84
55 INT171015 Positive_regulation of Positive_regulation of CCL5 3 0.42 3.63 1.51 63.84
56 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 63.60
57 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26 63.60
58 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 63.56
59 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84 62.92
60 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 62.92
61 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 62.92
62 INT116717 Gene_expression of CCR7 37 0.76 34.1 7.48 62.92
63 INT182242 Gene_expression of CXCR6 3 0.27 2.72 1.83 62.92
64 INT195211 Gene_expression of CCR10 2 0.25 1.31 0.71 62.92
65 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 61.68
66 INT83531 Gene_expression of KITLG 54 0.65 26 7.07 61.36
67 INT99574 Positive_regulation of KITLG 10 0.39 6.74 2.96 61.36
68 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 60.64
69 INT4240 Positive_regulation of CCL5 32 0.58 20.55 10.65 60.64
70 INT173537 Binding of CCL16 18 0.40 13.02 7.36 60.40
71 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 60.00
72 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 60.00
73 INT46619 Gene_expression of CSF1 80 0.73 36.63 12.94 59.44
74 INT17283 Positive_regulation of CSF1 37 0.59 24.16 10.01 59.44
75 INT108479 Positive_regulation of CCL21 18 0.67 19.93 10.76 58.64
76 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 56.80
77 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 56.80
78 INT58602 Gene_expression of HMI 34 0.65 25.26 3.74 56.00
79 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 52.44
80 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69 52.28
81 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66 52.28
82 INT108480 Gene_expression of CCL21 53 0.77 37.87 14.42 51.92
83 INT171058 Negative_regulation of PDX1 5 0.32 9.31 2.72 51.84
84 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 51.64
85 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 51.44
86 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 50.72
87 INT5454 Localization of CRH 124 0.79 79.18 41.53 50.20
88 INT171060 Gene_expression of PDX1 72 0.75 72.57 17.97 46.84
89 INT695 Binding of POMC 304 0.48 56.66 126.85 43.04
90 INT249847 Positive_regulation of Msc 6 0.26 3.36 0.84 42.52
91 INT15610 Localization of GOPC 223 0.65 68.26 28.7 36.92
92 INT100621 Localization of HLA-DRA 7 0.40 2.86 1.2 36.92
93 INT8629 Positive_regulation of COL7A1 72 0.69 40.66 12.09 36.20
94 INT39374 Gene_expression of Sct 5 0.68 1.42 3.89 34.88
95 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 33.72
96 INT209033 Positive_regulation of Localization of IFN1@ 27 0.67 12.55 2.84 33.56
97 INT91663 Positive_regulation of Localization of IL12A 9 0.27 5.91 1.95 33.56
98 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 33.12
99 INT91667 Localization of IL12A 39 0.74 25.51 7.36 33.12
100 INT78895 Regulation of CCL5 30 0.46 20.45 10.18 32.32
101 INT63177 Regulation of HP 71 0.44 39.48 5.86 32.32
102 INT11359 Gene_expression of PLAU 84 0.76 49.54 12.31 31.84
103 INT115721 Positive_regulation of Gene_expression of PLAU 11 0.67 7.66 1.55 31.84
104 INT271570 Gene_expression of MIR1-1 21 0.65 11.49 1.03 31.28
105 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 29.84
106 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 29.20
107 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 29.20
108 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 29.20
109 INT14009 Gene_expression of Sst 66 0.77 19.6 37.3 27.96
110 INT90350 Gene_expression of Gast 27 0.78 14.07 4.74 27.96
111 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73 25.68
112 INT20922 Positive_regulation of Localization of CRH 18 0.67 11.12 6.79 25.28
113 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 24.76
114 INT103806 Negative_regulation of Aaiq4 4 0.41 3.72 0.31 24.08
115 INT6174 Regulation of Gene_expression of POMC 49 0.61 9.75 27.69 23.28
116 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 22.68
117 INT1647 Negative_regulation of FSHR 54 0.45 13.44 8.87 21.40
118 INT173505 Localization of Hand2 63 0.57 45.32 13.66 19.64
119 INT9683 Binding of GH1 57 0.47 21.14 5.99 19.56
120 INT300943 Regulation of Localization of HOXA10 1 0.21 1.02 0.24 16.64
121 INT300941 Regulation of Localization of PGR 1 0.04 1.02 0.24 16.64
122 INT83236 Localization of PGR 14 0.73 8.26 2.23 14.72
123 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 14.48
124 INT69723 Gene_expression of SERPINB2 7 0.60 4.54 1.28 14.48
125 INT300945 Regulation of Gene_expression of MIR1-1 1 0.00 0.1 0 14.32
126 INT194590 Localization of HOXA10 1 0.35 1.54 0.59 12.08
127 INT284938 Regulation of DNMT1 2 0.22 1.17 0.24 6.80
128 INT300944 Regulation of DNMT3A 1 0.21 0.91 0.24 6.52
129 INT180250 Positive_regulation of GLUL 23 0.29 7.57 3.23 6.16
130 INT46336 Regulation of DNMT3B 12 0.53 4.91 1.25 6.04
131 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 5.00
132 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
133 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
134 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
135 INT626 Localization of CALCA 289 0.81 125.39 221.15 5.00
136 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
137 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
138 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
139 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
140 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 5.00
141 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
142 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 5.00
143 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
144 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
145 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
146 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
147 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
148 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 5.00
149 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27 5.00
150 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
151 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 5.00
152 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
153 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 5.00
154 INT3034 Localization of Ngf 126 0.81 50.81 72.84 5.00
155 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
156 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
157 INT6849 Localization of IL1B 229 0.81 112.56 69.63 5.00
158 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26 5.00
159 INT9489 Gene_expression of SFTPA1 112 0.66 55.38 66.45 5.00
160 INT253 Regulation of PRL 184 0.62 47.27 65.79 5.00
161 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9 5.00
162 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
163 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 5.00
164 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
165 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03 5.00
166 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 5.00
167 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
168 INT5118 Regulation of SST 97 0.62 34.35 51.74 5.00
169 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
170 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
171 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 5.00
172 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
173 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
174 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
175 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 5.00
176 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
177 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 5.00
178 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
179 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 5.00
180 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
181 INT8835 Localization of SFTPA1 65 0.68 32.81 38.65 5.00
182 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 5.00
183 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 5.00
184 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 5.00
185 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
186 INT100733 Positive_regulation of F2RL1 62 0.70 59.14 35.22 5.00
187 INT692 Negative_regulation of SST 72 0.59 28.68 34.52 5.00
188 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
189 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 5.00
190 INT10763 Localization of IL2 157 0.80 81.11 33.21 5.00
191 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92 5.00
192 INT65698 Localization of CCL2 118 0.81 77.54 32.69 5.00
193 INT691 Binding of SST 67 0.48 24.66 32.67 5.00
194 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 5.00
195 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68 5.00
196 INT23435 Positive_regulation of NGF 54 0.70 32.41 30.11 5.00
197 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 5.00
198 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
199 INT1196 Positive_regulation of Positive_regulation of POMC 51 0.70 15.99 28.58 5.00
200 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
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