D:Chromosome Aberrations

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Disease Term
Synonyms Aberration Chromosomal, Aberration Chromosome, Aberration Cytogenetic, Aberrations Chromosomal, ABERRATIONS CHROMOSOME, Aberrations Cytogenetic, Abnormal Karyotype, Abnormal Karyotypes, Abnormalities Autosome, Abnormalities Chromosomal, ABNORMALITIES CHROMOSOME
Documents 389
Hot Single Events 200
Hot Interactions 9

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Chromosome Aberrations. They are ordered first by their relevance to Chromosome Aberrations and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT277012 Binding of PAPPA and ACE2 1 0.02 1.26 0.15 99.92
2 INT297124 Binding of INCENP and Hephl1 1 0.00 0.17 0 98.68
3 INT7204 Binding of IFNA1 and IFNG 1 0.01 1.34 0.11 94.64
4 INT208152 Binding of CDK4 and MDM2 1 0.01 1.11 0 94.56
5 INT206848 PLP1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04 89.84
6 INT206845 ANXA1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04 89.84
7 INT206851 NR4A1 Regulation of Gene_expression of ESR1 1 0.08 0.9 0.04 89.84
8 INT259051 Binding of TP53 and UBE3A 1 0.01 3.48 0 86.32
9 INT190137 Binding of S100A12 and Gfap 1 0.00 0.65 0 83.60
10 INT277010 Binding of PAPPA and TNNT1 1 0.24 0.99 0.07 79.72
11 INT277016 Binding of MB and PAPPA 1 0.10 1 0.07 79.72
12 INT304013 Binding of SUZ12 and JAZF1 1 0.30 1.89 0 78.12
13 INT259050 Binding of HPV18I1 and OPN1LW 1 0.01 1.19 0 77.28
14 INT259049 Binding of BAK1 and HPV18I1 1 0.00 1.19 0 77.28
15 INT294880 DPYD Positive_regulation of Ephb1 1 0.00 0.53 0 76.48
16 INT294831 DPYD Positive_regulation of Positive_regulation of RASGRP1 1 0.00 0.53 0 76.48
17 INT282558 POU5F1 Positive_regulation of MAPK1 1 0.16 0.26 0 75.96
18 INT282607 POU5F1 Positive_regulation of Mdk 1 0.08 0.26 0 75.96
19 INT225228 Binding of Cdk4 and Cdkn2a 1 0.21 1.24 0 74.72
20 INT225229 Binding of Cdk6 and Cdkn2a 1 0.19 1.25 0 74.72
21 INT175399 Binding of TP53 and SACM1L 1 0.00 2.37 0 73.52
22 INT325375 Binding of Tp53 and Positive_regulation of Positive_regulation of PARP1 1 0.05 0.59 0 72.60
23 INT305001 Binding of ACAN and TNFAIP6 1 0.28 1.22 0.14 70.16
24 INT320712 Binding of NRAS and PIK3CD 1 0.21 1.66 0 67.84
25 INT320715 NRAS Positive_regulation of PIK3CD 1 0.27 1.66 0 67.84
26 INT320713 NRAS Positive_regulation of AKT1 1 0.37 0.84 0 67.84
27 INT296163 Mcph1 Regulation of Tert 1 0.03 0.19 0 62.20
28 INT296164 Mcph1 Regulation of Chek1 1 0.25 0.19 0 62.20
29 INT296162 Mcph1 Regulation of Brca1 1 0.26 0.19 0 62.20
30 INT206846 ESR1 Regulation of Gene_expression of PLP1 1 0.06 1.02 0.05 61.04
31 INT225230 Ad Positive_regulation of Nf2 1 0.04 1.37 0.04 60.00
32 INT282551 SOX2 Regulation of POU5F1 1 0.24 0.45 0 58.32
33 INT282547 SOX2 Regulation of REXO1 1 0.12 0.23 0 58.32
34 INT282559 NANOG Regulation of POU5F1 1 0.14 0.45 0 57.60
35 INT282557 NANOG Regulation of REXO1 1 0.07 0.23 0 57.60
36 INT320714 Gene_expression of MDM2 Negative_regulation of TP53 1 0.16 0.88 0 46.96
37 INT326162 Binding of ABHD2 and Scrib 1 0.00 1.07 0 44.12
38 INT248765 Binding of RUNX1 and CSF2 1 0.02 1.36 0 44.08
39 INT326165 Binding of ABHD12 and Scrib 1 0.00 1.01 0 43.48
40 INT285945 IL17A Regulation of IL6 1 0.13 1.22 0.2 41.84
41 INT277703 Binding of Pdgfrb and Pdgfb 1 0.02 0.23 0 41.84
42 INT284892 AMH Regulation of Localization of FSHR 1 0.01 0.18 0 41.36
43 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 39.60
44 INT328775 Binding of Cd44 and Epcam 1 0.08 1.34 0 38.32
45 INT347226 Hck Regulation of Gene_expression of Lyn 1 0.10 0.08 0 32.36
46 INT347224 Lyn Regulation of Positive_regulation of Bcr 1 0.14 0.07 0 31.28
47 INT347225 Hck Regulation of Positive_regulation of Bcr 1 0.15 0.07 0 31.08
48 INT320786 Binding of Eng and Kdr 1 0.04 1.17 0.04 28.76
49 INT305002 Binding of HIF1A and SERPINE1 1 0.07 1.17 0.11 24.64
50 INT268395 Binding of APC and Kras 1 0.04 1.21 0 23.36
51 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33 23.32
52 INT188210 EGF Positive_regulation of OSM 1 0.28 0 0.07 23.32
53 INT188208 EGF Regulation of STAT3 1 0.46 0 0.07 21.00
54 INT305003 HIF1A Regulation of SERPINE1 1 0.11 2.3 0.19 18.48
55 INT175400 RASGRP1 Positive_regulation of MAP3K5 1 0.00 1.2 0 17.44
56 INT328780 Binding of TBK1 and Memo1 1 0.09 0.6 0 10.68
57 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
58 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95 5.00
59 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89 5.00
60 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87 5.00
61 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87 5.00
62 INT257745 SAGE1 Positive_regulation of AXL 1 0.07 1.96 0.69 5.00
63 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65 5.00
64 INT45780 GNRH1 Positive_regulation of PLOD1 3 0.07 1.02 0.63 5.00
65 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61 5.00
66 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61 5.00
67 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 5.00
68 INT285940 Binding of IL6 and IL17A 1 0.11 1.42 0.53 5.00
69 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46 5.00
70 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45 5.00
71 INT22674 Binding of SERPINE1 and PLAT 7 0.04 0.65 0.45 5.00
72 INT297689 Atn1 Regulation of Gene_expression of Il6 1 0.02 1.13 0.44 5.00
73 INT297694 Positive_regulation of Binding of Il10 and Il13ra1 1 0.01 1.12 0.44 5.00
74 INT188194 OSM Regulation of IL6 1 0.16 1.12 0.43 5.00
75 INT188205 OSM Regulation of LIF 1 0.09 1.12 0.43 5.00
76 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43 5.00
77 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43 5.00
78 INT297696 Binding of Il10 and Il13ra1 1 0.00 1.12 0.43 5.00
79 INT257738 PIK3CA Regulation of Localization of ACTN4 1 0.16 1.03 0.39 5.00
80 INT177396 Npy1r Positive_regulation of Negative_regulation of Npy 1 0.27 0.38 0.37 5.00
81 INT285935 IL6 Positive_regulation of Gene_expression of POU5F1 1 0.14 2.68 0.37 5.00
82 INT177400 RNY1 Positive_regulation of Negative_regulation of Npy 1 0.03 0.38 0.37 5.00
83 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35 5.00
84 INT254344 Binding of Col2a1 and Ncoa5 1 0.00 0.98 0.35 5.00
85 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35 5.00
86 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34 5.00
87 INT257746 SHC1 Positive_regulation of Positive_regulation of PIK3CA 1 0.26 1.04 0.34 5.00
88 INT172004 IL17A Positive_regulation of Gene_expression of IL6 2 0.14 1.35 0.34 5.00
89 INT188204 Negative_regulation of IL6 Positive_regulation of STAT3 1 0.28 0.54 0.34 5.00
90 INT312803 F2 Positive_regulation of NPEPPS 1 0.01 1.32 0.32 5.00
91 INT277011 CRP Positive_regulation of Gene_expression of F3 1 0.06 1.03 0.32 5.00
92 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 0.01 1.33 0.32 5.00
93 INT257743 Binding of PIK3CA and SHC1 1 0.21 1.03 0.31 5.00
94 INT294115 IDO1 Positive_regulation of PTGER2 1 0.02 0.36 0.31 5.00
95 INT294117 HGF Positive_regulation of PTGER2 1 0.02 0.36 0.31 5.00
96 INT194358 Binding of Ddt and Scgb1d2 1 0.01 0 0.31 5.00
97 INT257735 GAS6 Positive_regulation of Gene_expression of SAGE1 1 0.04 0.98 0.31 5.00
98 INT257739 SAGE1 Positive_regulation of DDR1 1 0.00 0.91 0.31 5.00
99 INT257744 Binding of PIK3R2 and SHC1 1 0.08 0.96 0.28 5.00
100 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27 5.00
101 INT257740 SAGE1 Positive_regulation of Gene_expression of AXL 1 0.07 0.72 0.27 5.00
102 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 5.00
103 INT188209 OSM Positive_regulation of MAPK1 1 0.35 0.47 0.27 5.00
104 INT220317 Binding of CPB1 and PLEKHM1 1 0.00 0.93 0.26 5.00
105 INT177398 Binding of Npy1r and Npy 1 0.18 0.73 0.24 5.00
106 INT177397 Binding of Npy5r and Npy 1 0.16 0.73 0.24 5.00
107 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23 5.00
108 INT188200 IL6ST Positive_regulation of STAT3 1 0.25 0.38 0.23 5.00
109 INT188195 GOPC Positive_regulation of MAPK1 2 0.21 0.32 0.22 5.00
110 INT188203 EGF Positive_regulation of Protein_catabolism of OSM 1 0.30 0.17 0.21 5.00
111 INT188201 OSM Positive_regulation of Phosphorylation of STAT3 1 0.40 0.24 0.21 5.00
112 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
113 INT276301 Binding of CCL21 and CXCL13 1 0.04 1.85 0.18 5.00
114 INT302295 PPARA Regulation of OAS2 1 0.01 0.72 0.17 5.00
115 INT277013 PLAT Positive_regulation of Gene_expression of F13A1 1 0.02 0.31 0.17 5.00
116 INT188199 IL6 Positive_regulation of MAPK1 1 0.27 0.25 0.16 5.00
117 INT194360 SNRPD1 Negative_regulation of Dbh 1 0.00 0 0.14 5.00
118 INT184704 Binding of Prrx2 and Sr1 1 0.21 1.65 0.13 5.00
119 INT175398 Binding of ERBB2 and VEGFA 2 0.16 1.34 0.13 5.00
120 INT175401 Binding of EGFR and VEGFA 2 0.13 1.49 0.13 5.00
121 INT220318 Binding of CPB1 and CCL2 1 0.01 0.46 0.13 5.00
122 INT158014 Binding of FLT1 and PGF 2 0.27 0.9 0.12 5.00
123 INT188197 LIF Positive_regulation of STAT3 1 0.35 0.27 0.12 5.00
124 INT188198 OSM Positive_regulation of STAT3 1 0.52 0.24 0.12 5.00
125 INT297695 Binding of Atn1 and Fut1 1 0.01 0.68 0.12 5.00
126 INT284891 FSHR Positive_regulation of Gene_expression of PLOD1 2 0.03 1.32 0.11 5.00
127 INT188202 HBE1 Positive_regulation of MAPK1 1 0.01 0.14 0.11 5.00
128 INT285948 IL17A Regulation of Gene_expression of TERT 1 0.00 0.58 0.11 5.00
129 INT188192 HBE1 Positive_regulation of LY6E 1 0.00 0.14 0.11 5.00
130 INT186240 Binding of AGRP and SCN5A 2 0.13 1.19 0.1 5.00
131 INT65676 Binding of CGA and PLOD1 3 0.23 1.68 0.1 5.00
132 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1 5.00
133 INT206856 Binding of Adm and Calcrl 1 0.04 1.76 0.1 5.00
134 INT191184 Binding of EGFR and GRB2 7 0.35 1.06 0.1 5.00
135 INT260070 Binding of PHF2 and SPTLC1 1 0.17 1.93 0.1 5.00
136 INT228809 Gtf3a Regulation of Rgs1 1 0.00 0.25 0.09 5.00
137 INT249117 Binding of Abl1 and Bcr 4 0.36 2.22 0.09 5.00
138 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09 5.00
139 INT228808 Smad7 Regulation of Rgs1 1 0.19 0.24 0.09 5.00
140 INT228810 Vwf Regulation of Stap1 1 0.00 0.24 0.09 5.00
141 INT228811 Gtf3a Regulation of Stap1 1 0.00 0.24 0.09 5.00
142 INT276304 PRDM1 Regulation of TSC1 1 0.01 1.29 0.09 5.00
143 INT276391 Prdm1 Regulation of TSC1 1 0.00 1.29 0.09 5.00
144 INT228807 Vwf Regulation of Rgs1 1 0.05 0.24 0.09 5.00
145 INT228812 Smad7 Regulation of Stap1 1 0.00 0.24 0.09 5.00
146 INT320789 NRP2 Positive_regulation of Binding of Flt1 and Kdr 1 0.00 0.68 0.08 5.00
147 INT294116 CIITA Regulation of Gene_expression of HLA-E 1 0.05 0.05 0.08 5.00
148 INT276375 Binding of Prdm1 and MIR9-1 1 0.12 1.12 0.08 5.00
149 INT276383 Binding of PRDM1 and Mirlet7a-1 1 0.39 1.12 0.08 5.00
150 INT320785 Binding of Flt1 and Kdr 1 0.15 0.67 0.08 5.00
151 INT320788 VEGFA Positive_regulation of Binding of Flt1 and Kdr 1 0.15 0.68 0.08 5.00
152 INT276334 Binding of Prdm1 and Mirlet7a-1 1 0.12 1.13 0.08 5.00
153 INT276384 Binding of Mirlet7a-1 and MIR9-1 1 0.39 1.12 0.08 5.00
154 INT279286 Binding of TXK and VEGFA 3 0.05 2.35 0.07 5.00
155 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07 5.00
156 INT285938 IL6 Positive_regulation of Gene_expression of TEP1 1 0.01 1.05 0.07 5.00
157 INT217651 Binding of ROS1 and fa 1 0.01 1.09 0.07 5.00
158 INT241144 PGF Positive_regulation of FLT1 1 0.40 1.03 0.07 5.00
159 INT206855 Binding of ESR1 and PPARA 1 0.03 1.21 0.07 5.00
160 INT187671 CGA Negative_regulation of Gene_expression of GNRH1 1 0.01 0 0.06 5.00
161 INT320795 Flt1 Negative_regulation of VEGFA 1 0.29 0.29 0.06 5.00
162 INT282552 POU5F1 Positive_regulation of FGF4 1 0.29 0.29 0.05 5.00
163 INT326125 Binding of CXCL3 and IL1RAPL1 1 0.01 1.16 0.05 5.00
164 INT206897 Binding of HTR1A and Adm 1 0.02 0.87 0.05 5.00
165 INT206900 Binding of HTR1A and Calca 1 0.01 0.88 0.05 5.00
166 INT285947 IL6 Regulation of IL17A 1 0.08 0.44 0.05 5.00
167 INT276337 Timp1 Positive_regulation of Il10 1 0.01 0.76 0.05 5.00
168 INT326128 Binding of CXCL3 and CXCL6 1 0.06 1.18 0.05 5.00
169 INT326127 Binding of CXCL3 and CXCR1 1 0.13 1.16 0.05 5.00
170 INT279284 TXK Regulation of KDR 3 0.05 2.22 0.04 5.00
171 INT276386 Gtf3a Regulation of PTPN6 1 0.00 0.86 0.04 5.00
172 INT206853 ESR1 Positive_regulation of Gene_expression of PCP4 1 0.08 1.39 0.04 5.00
173 INT276381 Timp1 Positive_regulation of CD44 1 0.07 0.72 0.04 5.00
174 INT282555 POU5F1 Positive_regulation of Positive_regulation of MAPK1 1 0.11 0.28 0.04 5.00
175 INT241143 VEGFA Positive_regulation of FLT1 1 0.20 0.51 0.04 5.00
176 INT206896 ESR1 Positive_regulation of Gene_expression of Nr1i3 1 0.00 0.36 0.04 5.00
177 INT206847 ESR1 Negative_regulation of Gene_expression of PTGER3 1 0.08 1.52 0.04 5.00
178 INT282556 POU5F1 Positive_regulation of GOPC 1 0.06 0.06 0.04 5.00
179 INT282540 STAT3 Positive_regulation of Positive_regulation of MAPK1 1 0.04 0.27 0.04 5.00
180 INT276392 Timp1 Regulation of PTPN6 1 0.02 0.87 0.04 5.00
181 INT276376 Gtf3a Regulation of CD44 1 0.00 0.86 0.04 5.00
182 INT285936 IL17A Positive_regulation of Gene_expression of POU5F1 1 0.10 0.34 0.04 5.00
183 INT206849 ESR1 Regulation of Gene_expression of ALDH1A1 1 0.11 2.26 0.04 5.00
184 INT187732 Binding of CYP19A1 and Cyp11a1 1 0.01 0.68 0.04 5.00
185 INT285944 IL6 Positive_regulation of Gene_expression of TERT 1 0.01 0.36 0.04 5.00
186 INT276385 Timp1 Regulation of CD44 1 0.04 0.87 0.04 5.00
187 INT206852 ESR1 Regulation of Gene_expression of CRABP2 1 0.08 1.52 0.04 5.00
188 INT282561 POU5F1 Positive_regulation of Gene_expression of NANOG 1 0.11 0.26 0.04 5.00
189 INT276377 Binding of Lgals1 and KRT20 1 0.00 1.11 0.03 5.00
190 INT206898 Binding of PPARA and Rxrg 1 0.00 1.36 0.03 5.00
191 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03 5.00
192 INT282543 KDM4C Regulation of POU5F1 1 0.06 0.08 0.03 5.00
193 INT174204 Binding of SYNE1 and IL19 1 0.06 0.47 0.03 5.00
194 INT217648 Binding of fa and Hmgcr 1 0.00 0.89 0.03 5.00
195 INT282542 KDM3A Regulation of POU5F1 1 0.06 0.08 0.03 5.00
196 INT276388 Il22 Positive_regulation of STAT3 1 0.03 1.3 0.03 5.00
197 INT276305 Binding of LGALS1 and KRT20 1 0.01 1.11 0.03 5.00
198 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03 5.00
199 INT287479 PSMB10 Positive_regulation of TBK1 1 0.00 0.59 0.03 5.00
200 INT312303 Positive_regulation of FLT1 Positive_regulation of VEGFA 1 0.38 0.73 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Chromosome Aberrations. They are ordered first by their pain relevance and then by number of times they were reported in Chromosome Aberrations. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT61378 Positive_regulation of Bcar1 13 0.45 2.84 2.45 100.00
2 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 100.00
3 INT134823 Positive_regulation of Positive_regulation of Bcar1 2 0.27 0.38 0.17 100.00
4 INT21523 Positive_regulation of Ctnnd1 1 0.27 0.35 1.4 100.00
5 INT3405 Gene_expression of BCAR1 14 0.71 8.89 4.02 100.00
6 INT87340 Negative_regulation of BCAR1 8 0.38 6.96 2.63 100.00
7 INT183820 Regulation of BCAR1 4 0.39 3.27 1.06 100.00
8 INT276404 Regulation of IGH@ 1 0.22 1.33 0.03 99.98
9 INT276403 Regulation of MALT1 3 0.34 3.37 0.03 99.98
10 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 99.96
11 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 99.96
12 INT10371 Localization of ARMC9 6 0.49 1.24 0.08 99.96
13 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45 99.96
14 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53 99.96
15 INT800 Negative_regulation of Grhpr 21 0.42 10.3 7.17 99.92
16 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 99.90
17 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 99.62
18 INT277700 Binding of Pdgfb 1 0.09 0.67 0 99.48
19 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 99.46
20 INT287483 Negative_regulation of Localization of IGH@ 1 0.15 1.3 0.08 99.40
21 INT10372 Binding of ADI1 3 0.10 1.67 0.12 99.32
22 INT180739 Binding of ACE2 5 0.37 7.88 0.45 99.24
23 INT190023 Negative_regulation of Mrc1 15 0.25 12.36 0.16 99.22
24 INT171091 Positive_regulation of SLC10A4 8 0.16 6.27 0.99 99.20
25 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 99.20
26 INT209607 Localization of IGH@ 3 0.34 2.5 0.22 99.20
27 INT15745 Negative_regulation of GYPA 18 0.43 8.01 2.74 99.20
28 INT49312 Binding of Klk1b1 1 0.36 0.43 0.08 99.12
29 INT81229 Binding of COL1A1 24 0.35 12.07 3.3 99.08
30 INT192785 Regulation of Myo5a 4 0.05 9.05 0.93 99.04
31 INT194993 Binding of RB1 15 0.37 10.96 0.4 99.00
32 INT102601 Positive_regulation of Psmd11 1 0.69 0.85 0.31 98.92
33 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87 98.92
34 INT49311 Binding of Hprt 3 0.26 0.95 0.26 98.88
35 INT273555 Negative_regulation of Bcr 17 0.57 9.65 0.44 98.76
36 INT8101 Binding of INCENP 42 0.31 16.2 6.68 98.68
37 INT174100 Gene_expression of YWHAE 14 0.31 12.42 0.08 98.68
38 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 98.58
39 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28 98.12
40 INT128159 Positive_regulation of DDIT3 29 0.67 29.5 8.99 98.04
41 INT168502 Positive_regulation of FUS 3 0.39 9.22 0.59 98.04
42 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 97.84
43 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 97.84
44 INT12464 Binding of MET 38 0.47 10.3 13.15 97.80
45 INT185005 Negative_regulation of Gene_expression of TOP2B 3 0.41 1.75 0.57 97.72
46 INT104979 Gene_expression of MITF 51 0.62 54.83 6.91 97.60
47 INT217825 Regulation of Gene_expression of MITF 3 0.00 5.2 1.47 97.60
48 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4 97.48
49 INT82798 Regulation of MYC 19 0.60 12.06 2.31 97.48
50 INT20418 Regulation of Gene_expression of MYC 6 0.60 4.4 1.29 97.48
51 INT43637 Positive_regulation of AXL 11 0.58 11.71 1.59 97.40
52 INT121493 Gene_expression of XRCC1 55 0.65 73.43 2.76 97.32
53 INT185017 Gene_expression of TOP2B 7 0.75 4.84 1.67 97.24
54 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 97.20
55 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54 97.16
56 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 96.52
57 INT113913 Binding of Hephl1 23 0.27 1.57 0.19 96.52
58 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47 96.24
59 INT217639 Binding of fa 1 0.02 1.1 0.03 96.16
60 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 96.08
61 INT99629 Localization of GSTM1 8 0.80 6.72 0.04 95.60
62 INT45041 Gene_expression of IGLL1 18 0.66 15.45 1.59 95.36
63 INT260380 Negative_regulation of Gene_expression of IGLL1 3 0.02 1.46 0 95.36
64 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42 95.24
65 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 95.16
66 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39 95.16
67 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 95.12
68 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41 94.92
69 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 94.72
70 INT185284 Binding of CDK4 7 0.25 4.79 0.07 94.56
71 INT105884 Binding of Bcl2 19 0.35 15.67 3 94.24
72 INT17379 Positive_regulation of Prlh 6 0.64 0.58 3.68 93.92
73 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61 93.80
74 INT113346 Binding of MDM2 10 0.35 5.73 0.15 93.44
75 INT195993 Localization of STARD13 1 0.01 2.58 0 93.12
76 INT195992 Localization of FRA12E 1 0.01 1.11 0 92.96
77 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93 92.80
78 INT75498 Positive_regulation of Gene_expression of CCND1 21 0.68 19.4 0.51 92.80
79 INT77925 Negative_regulation of TEP1 21 0.53 15.23 2.62 92.00
80 INT8558 Negative_regulation of Hba-a1 2 0.11 0.57 0.05 91.84
81 INT65684 Gene_expression of MDM2 30 0.62 24.94 1.55 91.80
82 INT144275 Negative_regulation of Atm 9 0.59 8.48 0.36 91.28
83 INT126457 Gene_expression of BCL6 34 0.66 22.45 1.75 91.28
84 INT197121 Positive_regulation of Atm 24 0.69 6.81 0.25 91.28
85 INT47030 Negative_regulation of ARMC9 22 0.38 13.08 0.47 91.24
86 INT225225 Negative_regulation of Gene_expression of Cyp2b10 2 0.29 2.43 0.27 91.24
87 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36 90.92
88 INT183399 Gene_expression of Cyp2b10 17 0.39 18.39 0.71 90.92
89 INT320720 Gene_expression of TBX3 1 0.29 3.53 0 90.48
90 INT320726 Negative_regulation of Gene_expression of TBX3 1 0.16 0.66 0 90.48
91 INT320733 Negative_regulation of TBX3 1 0.16 0.66 0 90.48
92 INT355761 Gene_expression of PBOV1 1 0.02 0.35 0 90.32
93 INT82795 Binding of MYC 16 0.47 6.1 0.9 90.08
94 INT320729 Positive_regulation of Negative_regulation of RPP14 1 0.32 1.04 0 90.08
95 INT320723 Negative_regulation of Gene_expression of BRAF 2 0.38 1 0.03 89.92
96 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 89.84
97 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47 89.84
98 INT238201 Gene_expression of JAK2 9 0.70 7.09 0.81 89.72
99 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 89.64
100 INT320731 Positive_regulation of RPP14 1 0.34 1.04 0 89.64
101 INT320719 Negative_regulation of RPP14 1 0.30 1.04 0 89.64
102 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21 89.52
103 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49 89.40
104 INT277702 Positive_regulation of Gene_expression of Pdgfb 2 0.10 0.55 0.05 89.12
105 INT61626 Transcription of IL6 73 0.72 42.04 17.86 89.04
106 INT171096 Transcription of PDGFA 5 0.47 4.42 0.79 89.04
107 INT90890 Positive_regulation of RARA 25 0.67 9.32 4.2 88.72
108 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21 88.72
109 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 88.60
110 INT277699 Gene_expression of Pdgfb 5 0.20 4.84 0.59 88.48
111 INT57105 Positive_regulation of CD33 7 0.45 5.08 0.63 88.24
112 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 88.24
113 INT56032 Positive_regulation of NCAM1 38 0.49 26.01 4.68 88.24
114 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28 88.24
115 INT48357 Positive_regulation of Anpep 7 0.39 2.04 1.75 88.24
116 INT134824 Negative_regulation of Top2a 1 0.41 0.61 0.13 88.08
117 INT132521 Gene_expression of BRAF 14 0.65 13.59 0.73 88.00
118 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63 87.84
119 INT253423 Negative_regulation of CSF2RB 3 0.33 0.92 0.08 87.84
120 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 87.80
121 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38 87.80
122 INT196323 Localization of Cdkn2a 8 0.73 9.1 0.32 87.64
123 INT225223 Localization of Cdkn2b 2 0.62 1.29 0.37 87.64
124 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 87.60
125 INT180599 Gene_expression of EEC1 5 0.63 2.73 0.23 87.44
126 INT287086 Regulation of Gene_expression of EEC1 1 0.36 0.42 0 87.44
127 INT191208 Regulation of ZNRD1 1 0.01 6 0 87.28
128 INT277697 Positive_regulation of Positive_regulation of Pdgfrb 1 0.06 0.49 0 87.16
129 INT165469 Gene_expression of fa 3 0.14 2.71 0.98 87.08
130 INT179078 Regulation of Gene_expression of Myc 6 0.62 3.02 0 86.84
131 INT3098 Positive_regulation of Epo 46 0.70 28.27 7 86.80
132 INT172445 Positive_regulation of Gene_expression of Myc 58 0.70 39.62 0.25 86.80
133 INT320728 Gene_expression of APITD1 1 0.60 1.44 0 86.76
134 INT33133 Positive_regulation of ITGA2B 13 0.67 4.09 1.44 86.72
135 INT144020 Positive_regulation of Pdgfrb 30 0.69 24.8 1.92 86.72
136 INT201524 Localization of Wnt2 14 0.62 9.24 0.46 86.72
137 INT48246 Gene_expression of PLP1 18 0.64 10.33 4.73 86.64
138 INT206882 Regulation of PLP1 1 0.13 0.84 0.04 86.64
139 INT248768 Localization of SET 3 0.44 2.38 0.17 86.48
140 INT812 Localization of INS 1026 0.81 515.6 145.31 86.44
141 INT94784 Binding of ROS1 113 0.40 71.57 10.26 86.44
142 INT68846 Gene_expression of Tfrc 22 0.32 10.1 3.06 86.32
143 INT185035 Regulation of ERBB3 3 0.42 6.5 0.06 86.24
144 INT106745 Localization of CRP 65 0.81 66.44 15.21 86.24
145 INT178927 Regulation of Gene_expression of Tp53 6 0.26 2.23 0 86.20
146 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02 85.96
147 INT89774 Gene_expression of NR4A1 13 0.77 9.47 1.02 85.92
148 INT109596 Gene_expression of Itgae 5 0.42 2.82 0.28 85.92
149 INT206872 Regulation of NR4A1 3 0.17 1.11 0.07 85.92
150 INT294133 Regulation of Gene_expression of NT5E 4 0.12 1.36 0.71 85.88
151 INT62784 Gene_expression of NT5E 46 0.65 15.95 3.72 85.88
152 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08 85.88
153 INT119834 Phosphorylation of PTEN 12 0.79 6.78 0.75 85.80
154 INT271963 Phosphorylation of TSC1 2 0.31 2.02 0 85.80
155 INT248771 Localization of IGKV6-21 1 0.01 2.24 0.08 85.68
156 INT259063 Binding of UBE3A 2 0.36 1.15 0.09 85.56
157 INT134798 Gene_expression of ANXA1 15 0.75 13.94 2.99 85.36
158 INT206858 Regulation of ANXA1 3 0.56 2.4 0.45 85.36
159 INT206862 Regulation of Gene_expression of ANXA1 2 0.18 1.76 0.04 85.36
160 INT200806 Binding of EEC1 6 0.39 4.24 0.29 85.32
161 INT191210 Regulation of LOC340268 1 0.01 5.97 0 85.28
162 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61 85.24
163 INT101859 Gene_expression of MCF2 34 0.49 19.45 1.51 85.12
164 INT171092 Positive_regulation of Gene_expression of MCF2 6 0.05 1.57 0.1 85.12
165 INT57338 Gene_expression of ITGAX 31 0.75 24.62 4.39 84.80
166 INT320708 Binding of PMVK 1 0.36 0.58 0.03 84.80
167 INT191209 Regulation of TAS2R30 1 0.01 5.96 0 84.48
168 INT192342 Phosphorylation of PDGFRB 11 0.80 1.68 0.43 84.40
169 INT192338 Positive_regulation of Phosphorylation of PDGFRB 4 0.45 0.48 0.07 84.40
170 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 84.32
171 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 84.08
172 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 84.08
173 INT202848 Gene_expression of Nf2 5 0.59 4.93 0.63 84.08
174 INT186508 Regulation of KCNN3 2 0.45 7.41 1.03 83.92
175 INT18480 Positive_regulation of ANPEP 9 0.59 5.18 2.13 83.84
176 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 83.80
177 INT124375 Gene_expression of Wnt2 67 0.56 38.03 4.67 83.76
178 INT57187 Positive_regulation of Gfap 49 0.69 27.59 11.46 83.60
179 INT25356 Positive_regulation of S100A12 18 0.69 17.62 3.38 83.60
180 INT57106 Positive_regulation of CD7 3 0.43 2.23 0.26 83.36
181 INT179036 Gene_expression of Fez1 1 0.70 13.28 0.11 82.84
182 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 82.84
183 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 82.84
184 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9 82.84
185 INT123733 Gene_expression of Fhit 5 0.78 12.34 0.26 82.84
186 INT179035 Gene_expression of Cdcs1 1 0.06 1.18 0 82.84
187 INT136921 Gene_expression of NOTCH3 5 0.67 4.27 0.16 82.76
188 INT175419 Positive_regulation of Gene_expression of NOTCH3 1 0.32 3 0 82.76
189 INT346712 Localization of RCN1 1 0.72 2.14 0 82.64
190 INT36193 Negative_regulation of HTC2 4 0.38 3.11 0.65 82.64
191 INT191179 Regulation of MCF2 12 0.06 8.54 0.14 82.56
192 INT202203 Positive_regulation of GSTT1 4 0.47 1.26 0 82.40
193 INT144302 Protein_catabolism of MMP3 7 0.86 7.43 3.98 82.28
194 INT60585 Regulation of TP53 59 0.59 54.55 5.21 82.24
195 INT259061 Negative_regulation of Regulation of TP53 2 0.10 2.23 0.03 82.24
196 INT69561 Positive_regulation of GSTM1 23 0.50 5.69 6.36 81.84
197 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 81.68
198 INT91509 Localization of CYC1 39 0.78 34.74 7.17 81.68
199 INT19335 Positive_regulation of CYC1 11 0.67 9.82 2.92 81.68
200 INT179885 Regulation of PTEN 8 0.26 11.88 2.18 81.68
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