D:Chromosome Breakage

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pChart

Disease Term
Synonyms BREAK CHROMOSOMAL, BREAK CHROMOSOME, Breakage Chromosomal, Breakage Chromosome, Breakages Chromosomal, Breakages Chromosome, BREAKS CHROMOSOMAL, BREAKS CHROMOSOME, Chromosomal Break, Chromosomal Breakage, Chromosomal Breakages
Documents 17
Hot Single Events 1
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Chromosome Breakage. They are ordered first by their relevance to Chromosome Breakage and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT296163 Mcph1 Regulation of Tert 1 0.03 0.19 0 67.52
2 INT296164 Mcph1 Regulation of Chek1 1 0.25 0.19 0 67.52
3 INT296162 Mcph1 Regulation of Brca1 1 0.26 0.19 0 67.52
4 INT174204 Binding of SYNE1 and IL19 1 0.06 0.47 0.03 5.00
5 INT174203 Binding of NTSR1 and FMN1 1 0.01 0.06 0 5.00
6 INT352392 Binding of ENOSF1 and Recql4 1 0.02 6.62 0 5.00
7 INT174205 PPIG Positive_regulation of CPA1 1 0.01 0.33 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Chromosome Breakage. They are ordered first by their pain relevance and then by number of times they were reported in Chromosome Breakage. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT100650 Gene_expression of Recql4 2 0.42 1.72 0.28 93.56
2 INT296160 Localization of Mcph1 1 0.75 0.13 0 63.40
3 INT174230 Positive_regulation of Gene_expression of IL12B 6 0.49 3.2 1.56 53.20
4 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89 51.32
5 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 24.48
6 INT296139 Regulation of Localization of Trp53bp1 1 0.22 0.07 0 20.48
7 INT296161 Regulation of Localization of Mcph1 1 0.45 0.07 0 20.48
8 INT296153 Localization of Trp53bp1 1 0.37 0.07 0 19.92
9 INT296152 Negative_regulation of Mcph1 1 0.59 0.83 0 12.68
10 INT296145 Regulation of Mcph1 1 0.45 0.18 0.04 9.36
11 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 5.00
12 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
13 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 5.00
14 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 5.00
15 INT756 Gene_expression of C3 138 0.75 100.6 19.2 5.00
16 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
17 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 5.00
18 INT60764 Positive_regulation of PPIG 39 0.67 17.08 13.48 5.00
19 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 5.00
20 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
21 INT70877 Gene_expression of PPIG 72 0.75 22.39 10.93 5.00
22 INT22210 Gene_expression of CYP1A2 45 0.78 4.95 10.66 5.00
23 INT10019 Binding of CD8A 57 0.36 31.49 10.08 5.00
24 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76 5.00
25 INT57922 Gene_expression of CYP2C9 65 0.78 22.24 7.53 5.00
26 INT50212 Gene_expression of Ifx 33 0.75 32.17 7.26 5.00
27 INT68661 Positive_regulation of NTSR1 11 0.69 9.6 5.91 5.00
28 INT53196 Binding of Cd4 44 0.47 27.28 5.85 5.00
29 INT68899 Binding of CYP1A2 19 0.48 2.33 5.73 5.00
30 INT86023 Transcription of PPARA 60 0.66 25.8 5.7 5.00
31 INT18772 Positive_regulation of Gene_expression of CYP2B6 14 0.49 2.93 5.4 5.00
32 INT114499 Gene_expression of MCPH1 38 0.67 26.68 4.55 5.00
33 INT113107 Phosphorylation of Hist1h3f 21 0.51 8.01 4.45 5.00
34 INT26404 Positive_regulation of ATM 15 0.49 10.94 4.39 5.00
35 INT3327 Protein_catabolism of PRSS1 22 1.00 6.96 4.29 5.00
36 INT65072 Gene_expression of TKT 16 0.65 17.58 3.55 5.00
37 INT174232 Gene_expression of PNP 36 0.30 8.74 3.17 5.00
38 INT141180 Gene_expression of Apaf1 6 0.74 5.77 2.98 5.00
39 INT8095 Gene_expression of ERBB3 47 0.77 24.85 2.82 5.00
40 INT22212 Gene_expression of CYP1A1 34 0.76 10.11 2.77 5.00
41 INT68658 Gene_expression of NTSR1 17 0.77 7.88 2.32 5.00
42 INT150192 Positive_regulation of CPA1 3 0.23 1.29 2.2 5.00
43 INT12131 Gene_expression of POR 17 0.77 9.42 2.17 5.00
44 INT65424 Positive_regulation of Gene_expression of CYP1A2 6 0.70 2.01 2.01 5.00
45 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 5.00
46 INT174240 Negative_regulation of TYMS 12 0.57 6.35 1.82 5.00
47 INT144380 Gene_expression of SYNE1 12 0.58 6.99 1.55 5.00
48 INT101859 Gene_expression of MCF2 34 0.49 19.45 1.51 5.00
49 INT90377 Gene_expression of HBA1 26 0.75 7.34 1.51 5.00
50 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47 5.00
51 INT174242 Gene_expression of CYP4B1 4 0.49 3.54 1.32 5.00
52 INT71281 Positive_regulation of Gene_expression of CYP2C9 13 0.62 5.11 1.3 5.00
53 INT57169 Gene_expression of Cyp2b1 5 0.72 1.39 1.2 5.00
54 INT141179 Negative_regulation of Apaf1 2 0.41 1.53 1.14 5.00
55 INT3046 Gene_expression of LGALS1 20 0.75 12.48 1.11 5.00
56 INT118952 Gene_expression of Hist1h3f 13 0.21 3.58 1.05 5.00
57 INT19803 Gene_expression of Hprt 15 0.67 4.81 1.03 5.00
58 INT164416 Gene_expression of CDA 8 0.64 5.17 1.02 5.00
59 INT66492 Negative_regulation of CES2 8 0.42 0.73 0.96 5.00
60 INT155860 Positive_regulation of ENOSF1 5 0.19 3.15 0.95 5.00
61 INT143115 Positive_regulation of Gene_expression of NTSR1 4 0.12 2.97 0.73 5.00
62 INT155861 Negative_regulation of ENOSF1 3 0.42 3.29 0.63 5.00
63 INT174239 Gene_expression of CYP2C18 5 0.65 2.25 0.63 5.00
64 INT174229 Binding of CPA1 3 0.07 2 0.46 5.00
65 INT120235 Negative_regulation of Gene_expression of PPIG 4 0.41 0.92 0.43 5.00
66 INT104143 Transcription of EWSR1 7 0.67 8.1 0.42 5.00
67 INT119271 Positive_regulation of BCS1L 13 0.50 7.56 0.39 5.00
68 INT144826 Localization of CPA1 2 0.68 0.98 0.31 5.00
69 INT197599 Transcription of Rb1 4 0.63 0.87 0.3 5.00
70 INT181034 Localization of Zmat3 3 0.06 1.51 0.28 5.00
71 INT141791 Regulation of Ucp3 3 0.53 1.27 0.28 5.00
72 INT178479 Gene_expression of Angpt2 17 0.73 14.19 0.27 5.00
73 INT12132 Positive_regulation of Gene_expression of POR 5 0.31 1.96 0.27 5.00
74 INT39972 Gene_expression of CPA1 7 0.65 3.17 0.26 5.00
75 INT133858 Negative_regulation of BCS1L 13 0.51 8.65 0.2 5.00
76 INT296151 Gene_expression of Mcph1 1 0.78 1.33 0.19 5.00
77 INT174246 Localization of Cyp2b1 2 0.68 1.58 0.17 5.00
78 INT68655 Regulation of Gene_expression of NTSR1 1 0.61 0.48 0.16 5.00
79 INT205654 Gene_expression of FUS 9 0.32 11.53 0.16 5.00
80 INT163262 Transcription of ADIPOQ 5 0.52 2.81 0.14 5.00
81 INT174241 Gene_expression of ADCY5 2 0.65 1 0.14 5.00
82 INT172370 Binding of MCPH1 6 0.34 4.75 0.13 5.00
83 INT187590 Gene_expression of Brca1 12 0.65 4.94 0.11 5.00
84 INT174243 Positive_regulation of SYNE1 1 0.06 0.35 0.09 5.00
85 INT287295 Transcription of FLI1 1 0.38 0.79 0.08 5.00
86 INT174155 Negative_regulation of Brca1 4 0.36 1.77 0.07 5.00
87 INT207806 Phosphorylation of Atm 8 0.81 3.07 0.06 5.00
88 INT245905 Negative_regulation of Transcription of ADIPOQ 1 0.42 1.26 0.05 5.00
89 INT245901 Positive_regulation of Dlk1 1 0.25 0.48 0.04 5.00
90 INT245910 Regulation of Ucp2 1 0.12 0.93 0.04 5.00
91 INT245906 Regulation of Transcription of Ucp2 1 0.12 0.93 0.04 5.00
92 INT245909 Positive_regulation of Transcription of Rb1 1 0.05 0.49 0.04 5.00
93 INT228578 Transcription of Ucp2 2 0.29 1.19 0.04 5.00
94 INT245908 Regulation of Transcription of Ucp3 1 0.09 0.92 0.04 5.00
95 INT245907 Transcription of Ucp3 2 0.63 0.99 0.04 5.00
96 INT174235 Positive_regulation of CES2 2 0.50 0.63 0 5.00
97 INT296150 Negative_regulation of Gene_expression of Chek1 1 0.35 0.11 0 5.00
98 INT296146 Negative_regulation of Localization of Zmat3 1 0.04 0 0 5.00
99 INT296141 Transcription of Mcph1 1 0.69 0 0 5.00
100 INT296144 Phosphorylation of Nbn 1 0.32 0.59 0 5.00
101 INT287298 Regulation of SS18 1 0.26 0.84 0 5.00
102 INT296156 Gene_expression of Ddb2 1 0.34 0.11 0 5.00
103 INT174231 Negative_regulation of Gene_expression of NTSR1 1 0.10 0.67 0 5.00
104 INT287297 Gene_expression of CREB3L2 1 0.49 1.02 0 5.00
105 INT296158 Negative_regulation of Rad51 1 0.17 0.11 0 5.00
106 INT261190 Regulation of Hprt 3 0.60 0 0 5.00
107 INT296143 Negative_regulation of Ddb2 1 0.24 0.11 0 5.00
108 INT296149 Gene_expression of Trp73 1 0.23 0.11 0 5.00
109 INT174236 Positive_regulation of Gene_expression of CYP2C18 1 0.03 0.66 0 5.00
110 INT174237 Negative_regulation of Positive_regulation of CPA1 1 0.08 0.33 0 5.00
111 INT296155 Phosphorylation of Mdc1 1 0.19 0.59 0 5.00
112 INT208175 Positive_regulation of Negative_regulation of BCS1L 1 0.04 0 0 5.00
113 INT208174 Negative_regulation of Positive_regulation of BCS1L 1 0.04 0 0 5.00
114 INT296142 Negative_regulation of Trp73 1 0.16 0.11 0 5.00
115 INT187049 Localization of SLC35B2 1 0.44 1.34 0 5.00
116 INT296154 Positive_regulation of Gene_expression of Mcph1 1 0.50 0 0 5.00
117 INT212461 Gene_expression of Chek1 2 0.65 0.11 0 5.00
118 INT296147 Negative_regulation of Topbp1 1 0.11 0.11 0 5.00
119 INT174238 Positive_regulation of Gene_expression of PNP 2 0.16 0.69 0 5.00
120 INT296140 Negative_regulation of Chek1 1 0.35 0.45 0 5.00
121 INT296159 Gene_expression of Rad51 1 0.11 0.11 0 5.00
122 INT174233 Gene_expression of UPRT 1 0.58 2.9 0 5.00
123 INT174245 Positive_regulation of Gene_expression of CPA1 1 0.11 0.85 0 5.00
124 INT296148 Gene_expression of Topbp1 1 0.15 0.11 0 5.00
125 INT174234 Gene_expression of NDUFS7 1 0.01 0.82 0 5.00
126 INT287296 Regulation of SSX2 1 0.26 0.84 0 5.00
127 INT296157 Phosphorylation of Trp53bp1 1 0.16 0.59 0 5.00
128 INT208173 Positive_regulation of Positive_regulation of BCS1L 1 0.04 0 0 5.00
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