D:Chronic Inflammatory Demyelinating Polyradiculoneuropathy

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Disease Term
Synonyms CHRONIC INFLAMMATORY POLYRADICULONEUROPATHIES, Chronic Inflammatory Polyradiculoneuropathy, CHRONIC INFLAMMATORY POLYRADICULOPATHIES, Chronic Inflammatory Polyradiculopathy, CIDP, Inflammatory Polyradiculopathies Chronic, Inflammatory Polyradiculopathy Chronic, Polyradiculoneuropathies Chronic Inflammatory, POLYRADICULONEUROPATHY CHRONIC INFLAMMATORY, Polyradiculopathies Chronic Inflammatory, Polyradiculopathy Chronic Inflammatory
Documents 114
Hot Single Events 72
Hot Interactions 5

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Chronic Inflammatory Demyelinating Polyradiculoneuropathy. They are ordered first by their relevance to Chronic Inflammatory Demyelinating Polyradiculoneuropathy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT181443 Csf2 Positive_regulation of Cxcl10 1 0.02 1.69 0.39 86.24
2 INT181441 Csf2 Positive_regulation of Cxcl12 1 0.02 1.69 0.39 85.92
3 INT181439 Csf2 Positive_regulation of Ccl19 1 0.06 1.68 0.38 85.48
4 INT181447 Ccl3 Positive_regulation of Csf2 1 0.06 1.89 0.45 82.32
5 INT181444 Ccl5 Positive_regulation of Csf2 1 0.07 1.88 0.45 81.96
6 INT282129 Il10 Positive_regulation of Icam1 1 0.56 3.12 0.82 40.16
7 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66 25.36
8 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87 8.84
9 INT181452 Binding of Ccl19 and Ccl21b 1 0.02 2.22 0.86 8.44
10 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 5.00
11 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27 5.00
12 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04 5.00
13 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 5.00
14 INT85879 Il12a Positive_regulation of Gene_expression of Ifng 1 0.20 0.89 0.92 5.00
15 INT327999 Binding of FPR2 and FPR3 1 0.02 3.72 0.53 5.00
16 INT181448 Eae1 Positive_regulation of Gene_expression of Ccr2 1 0.04 4.98 0.42 5.00
17 INT181438 Il4 Regulation of Gene_expression of Ccl2 1 0.38 0.74 0.35 5.00
18 INT181453 Gene_expression of Ccl2 Positive_regulation of Gene_expression of Il12rb1 1 0.06 1.87 0.34 5.00
19 INT181451 Lck Regulation of Mbp 1 0.08 1.43 0.34 5.00
20 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32 5.00
21 INT181433 Hand2 Regulation of Gene_expression of Ccl2 1 0.12 0.68 0.32 5.00
22 INT181432 Csf2 Positive_regulation of Ccl5 1 0.03 0.81 0.29 5.00
23 INT181442 Ccl2 Positive_regulation of Localization of Hand2 1 0.26 0.63 0.29 5.00
24 INT181446 Csf2 Positive_regulation of Ccl3 1 0.05 0.81 0.29 5.00
25 INT282128 Gene_expression of Il10 Positive_regulation of Positive_regulation of Icam1 1 0.37 1.12 0.28 5.00
26 INT181454 Eae7 Regulation of Positive_regulation of Eae1 1 0.06 0.9 0.26 5.00
27 INT181449 Ccl7 Regulation of Ccl2 1 0.24 0.73 0.25 5.00
28 INT181445 Binding of Ccr5 and Hand1 1 0.12 1.01 0.22 5.00
29 INT181440 Binding of Ccr2 and Eae1 1 0.03 1.3 0.19 5.00
30 INT181457 Binding of CCL16 and Hand2 1 0.04 0.92 0.17 5.00
31 INT328004 Binding of CYBB and Gnb5 1 0.00 1.13 0.15 5.00
32 INT332581 Binding of Nqo1 and MRI1 1 0.01 1.68 0.12 5.00
33 INT307282 Binding of PMP2 and NPC2 1 0.21 0.08 0.04 5.00
34 INT307284 DCP2 Positive_regulation of HAL 1 0.00 0 0 5.00
35 INT307283 Binding of ABCA1 and PMP2 1 0.00 0 0 5.00
36 INT307286 Binding of PMP2 and DCP2 1 0.04 0 0 5.00
37 INT349355 CSF2 Negative_regulation of CSTA 1 0.01 1.43 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Chronic Inflammatory Demyelinating Polyradiculoneuropathy. They are ordered first by their pain relevance and then by number of times they were reported in Chronic Inflammatory Demyelinating Polyradiculoneuropathy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT110318 Gene_expression of CAPN1 1 0.04 1.97 0.82 100.00
2 INT16150 Positive_regulation of NKG7 10 0.69 10.26 1.73 99.36
3 INT62001 Negative_regulation of Cd68 1 0.33 1.88 0.48 99.24
4 INT62002 Regulation of Cd68 6 0.35 7.89 0.86 99.24
5 INT209033 Positive_regulation of Localization of IFN1@ 27 0.67 12.55 2.84 99.16
6 INT25238 Localization of REG1A 5 0.78 2.93 0.81 99.12
7 INT92237 Positive_regulation of Gene_expression of CXCL10 43 0.70 43.67 13.65 99.00
8 INT112971 Positive_regulation of Gene_expression of MIP 3 0.49 5.24 1.82 99.00
9 INT83293 Negative_regulation of MIP 2 0.41 4.12 2.02 98.92
10 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 98.74
11 INT83292 Gene_expression of MIP 35 0.75 25.22 10.14 98.74
12 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 98.70
13 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 98.70
14 INT260875 Binding of HLA-DRB2 2 0.01 1.33 0.4 98.68
15 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 98.52
16 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 98.50
17 INT38276 Negative_regulation of CXCL10 10 0.42 9.26 3.19 98.48
18 INT112968 Negative_regulation of Gnb5 5 0.34 7.79 1.81 98.04
19 INT25237 Binding of NRSN1 4 0.29 2.58 0.53 98.04
20 INT25236 Binding of REG1A 6 0.47 3.69 0.91 98.04
21 INT85878 Negative_regulation of Il12a 4 0.58 2.88 2.21 97.92
22 INT94335 Positive_regulation of CXCL10 71 0.58 50.69 23 97.52
23 INT96269 Positive_regulation of Mcpt1 71 0.61 52.38 20.4 97.36
24 INT112970 Regulation of Ccr1 8 0.29 7.77 1.93 96.88
25 INT112969 Negative_regulation of Mcpt1 30 0.45 20.17 10.11 96.56
26 INT170755 Positive_regulation of Positive_regulation of IFN1@ 17 0.67 8.72 3.65 96.40
27 INT92234 Regulation of CXCL10 15 0.42 8.37 5.09 96.08
28 INT181396 Transcription of Csf2 15 0.48 6.38 2.17 96.08
29 INT117630 Binding of NKG7 1 0.32 1.01 0.07 95.96
30 INT83294 Regulation of MIP 4 0.60 3.91 2.21 95.76
31 INT91326 Regulation of CCL4 4 0.44 2.86 1.69 95.76
32 INT112967 Regulation of Mcpt1 15 0.54 13.03 8.58 95.76
33 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 95.36
34 INT174432 Transcription of Cxcr3 8 0.68 15.73 7.32 94.96
35 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 94.84
36 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 94.84
37 INT6852 Localization of TNF 883 0.81 705.95 270.84 94.84
38 INT181358 Transcription of Ccr7 1 0.43 1.33 0.43 94.56
39 INT181397 Transcription of Ccr5 2 0.62 1.33 0.46 94.32
40 INT8959 Binding of Gnb5 17 0.40 31.38 5.1 94.28
41 INT163613 Transcription of CSF2 16 0.60 12.98 1.62 93.56
42 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 93.32
43 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 93.32
44 INT96271 Positive_regulation of Gene_expression of Mcpt1 30 0.53 21.34 11.06 90.56
45 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 90.56
46 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 90.00
47 INT6481 Binding of TNF 624 0.48 510.2 214.82 89.76
48 INT297067 Positive_regulation of RT1@ 1 0.03 0.93 0.28 89.76
49 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 89.72
50 INT250351 Positive_regulation of Gene_expression of Best1 5 0.27 3.14 0.65 89.72
51 INT297115 Gene_expression of TEX33 3 0.01 5.37 1.86 89.64
52 INT297113 Positive_regulation of Gene_expression of TEX33 2 0.01 3.87 1.14 89.64
53 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 89.32
54 INT227759 Gene_expression of Best1 26 0.42 20.36 1.73 89.32
55 INT285702 Negative_regulation of Tpmt 2 0.28 1.4 0.19 88.60
56 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94 88.32
57 INT105569 Binding of IGFALS 13 0.25 17.31 1.36 87.68
58 INT12345 Gene_expression of Il2 142 0.78 59.17 51.21 87.36
59 INT12344 Negative_regulation of Gene_expression of Il2 28 0.59 15.53 10.23 87.36
60 INT20608 Positive_regulation of Regulation of CST3 1 0.01 1.23 0.21 87.20
61 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 86.48
62 INT99780 Positive_regulation of Cxcl10 43 0.69 39.67 13.27 86.24
63 INT17349 Negative_regulation of Akr1b1 41 0.59 27.03 10.65 85.92
64 INT181386 Positive_regulation of Cxcl12 12 0.69 15.35 2.84 85.92
65 INT181370 Positive_regulation of Ccl19 2 0.37 2.28 0.77 85.48
66 INT38283 Positive_regulation of Cebpg 2 0.04 1.96 0.69 85.12
67 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 85.04
68 INT640 Regulation of CST3 9 0.60 4.04 2.26 83.76
69 INT128364 Positive_regulation of Ccl3 20 0.70 23.96 10.65 82.32
70 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83 81.96
71 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 81.52
72 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 80.32
73 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 79.68
74 INT135407 Negative_regulation of Ccl2 33 0.57 32.74 9.45 76.20
75 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41 75.80
76 INT1990 Positive_regulation of Ean5 35 0.41 38.05 28.8 75.68
77 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 75.00
78 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 75.00
79 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 73.68
80 INT35683 Gene_expression of Gsr 24 0.46 16.94 3.6 72.60
81 INT307302 Negative_regulation of Transcription of PMP2 1 0.34 0.56 0.06 68.36
82 INT139169 Gene_expression of Pmp22 10 0.68 8.37 2.5 67.44
83 INT61075 Gene_expression of PMP2 23 0.61 7.42 2.79 67.36
84 INT41844 Transcription of PMP2 3 0.69 0.8 0.34 67.36
85 INT54565 Binding of SCLC1 12 0.31 20.41 0.81 64.52
86 INT64982 Positive_regulation of Ifnb1 10 0.48 6.16 2.35 64.08
87 INT9695 Negative_regulation of Csf2 41 0.57 31.65 6.28 63.12
88 INT141024 Positive_regulation of TEX33 2 0.05 1.84 0.83 63.12
89 INT167679 Gene_expression of Ccr5 74 0.75 59.03 18.16 62.64
90 INT26962 Negative_regulation of IgG-2a 12 0.42 6.07 5.31 61.68
91 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58 55.00
92 INT303901 Negative_regulation of Gene_expression of Cd5 1 0.19 0.88 0.13 52.24
93 INT140413 Gene_expression of AQP4 113 0.78 139.25 25.53 50.44
94 INT230519 Gene_expression of Cd5 4 0.60 2.79 0.21 50.40
95 INT9344 Regulation of Atp9a 6 0.28 1.74 0.37 50.00
96 INT164512 Regulation of MPZ 12 0.30 8.38 1.53 49.52
97 INT144613 Regulation of NEFL 2 0.31 1.55 0.07 49.52
98 INT286054 Regulation of GJB1 1 0.08 1.04 0.07 49.52
99 INT181406 Binding of Ccr5 16 0.45 17 5.78 46.72
100 INT181415 Regulation of Regulation of Csf2 1 0.07 2.42 0.77 43.84
101 INT46721 Regulation of Csf2 26 0.45 20.4 6.18 42.80
102 INT140223 Regulation of Ccl2 15 0.45 13.1 5.41 42.80
103 INT181363 Regulation of Ccl5 16 0.46 13.65 5.09 42.80
104 INT166878 Regulation of Ccl3 9 0.44 8.21 4.81 42.80
105 INT181418 Regulation of Gene_expression of Ccl5 11 0.52 9.86 3.37 42.80
106 INT181355 Regulation of Gene_expression of Ccl2 12 0.44 10.37 3.21 42.80
107 INT181410 Regulation of Gene_expression of Ccl3 2 0.33 3.52 1.06 42.80
108 INT80905 Regulation of Ean5 1 0.15 2.08 1.54 42.32
109 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15 41.96
110 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01 41.60
111 INT181364 Regulation of Ccr5 3 0.32 1.81 0.62 41.12
112 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 40.40
113 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 39.08
114 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 38.52
115 INT10721 Gene_expression of BDNF-AS 119 0.76 72.8 16.29 34.88
116 INT90792 Localization of Il10 144 0.80 87.88 30.03 26.40
117 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 25.00
118 INT79439 Gene_expression of XCL1 9 0.65 5.18 3.84 25.00
119 INT116091 Regulation of XCL1 1 0.00 1.61 1.06 25.00
120 INT155808 Gene_expression of Ccl4 24 0.65 21.36 9.18 22.88
121 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 12.88
122 INT166966 Gene_expression of Ccr7 14 0.48 7.36 4.2 9.16
123 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.92
124 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
125 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
126 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
127 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 5.00
128 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14 5.00
129 INT11807 Gene_expression of Il2 266 0.78 112 64.97 5.00
130 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 5.00
131 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
132 INT109910 Gene_expression of CCL16 104 0.74 76.1 43.97 5.00
133 INT168410 Gene_expression of Cxcr3 81 0.75 84.03 37.01 5.00
134 INT118343 Positive_regulation of Eae1 121 0.39 136.06 34.87 5.00
135 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 5.00
136 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
137 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
138 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 5.00
139 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14 5.00
140 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51 5.00
141 INT137767 Gene_expression of Eae1 74 0.34 89.32 20.48 5.00
142 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81 5.00
143 INT25222 Positive_regulation of Gene_expression of Ifng 32 0.50 24.18 19.58 5.00
144 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 5.00
145 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85 5.00
146 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93 5.00
147 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 5.00
148 INT62546 Positive_regulation of Gene_expression of Icam1 60 0.70 59.52 16.9 5.00
149 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 5.00
150 INT56447 Positive_regulation of Icam1 64 0.64 64.14 16.16 5.00
151 INT52107 Transcription of IL8 63 0.72 41.66 16.06 5.00
152 INT36177 Binding of Alms1 70 0.31 35.47 13.81 5.00
153 INT94051 Positive_regulation of Arg1 41 0.60 36.22 13.72 5.00
154 INT173505 Localization of Hand2 63 0.57 45.32 13.66 5.00
155 INT20378 Localization of Hand1 53 0.71 41.96 13.31 5.00
156 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21 5.00
157 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 5.00
158 INT89294 Gene_expression of Ccr3 53 0.68 43.9 12.62 5.00
159 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04 5.00
160 INT36453 Binding of ABCA1 48 0.45 19.9 10.84 5.00
161 INT71768 Regulation of Gene_expression of Il10 27 0.62 19.17 10.4 5.00
162 INT71769 Negative_regulation of Gene_expression of Il10 40 0.57 22.53 10.37 5.00
163 INT181344 Gene_expression of Ccr6 28 0.61 24.34 9.78 5.00
164 INT181405 Gene_expression of Ccl20 26 0.65 23.02 9.46 5.00
165 INT140224 Localization of Ccl2 32 0.72 26.91 9.39 5.00
166 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28 5.00
167 INT138700 Negative_regulation of Gene_expression of Ccl2 27 0.57 24.1 9.08 5.00
168 INT250282 Negative_regulation of AQP4 32 0.54 32.96 9.07 5.00
169 INT161222 Positive_regulation of Ccr2 13 0.55 13.77 8.89 5.00
170 INT140411 Gene_expression of Nqo1 45 0.60 62.35 8.7 5.00
171 INT174422 Binding of Cxcr3 24 0.47 26.09 8.34 5.00
172 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 5.00
173 INT22056 Positive_regulation of CYBB 88 0.68 32.13 7.95 5.00
174 INT166881 Positive_regulation of Ccr1 31 0.69 18.14 7.9 5.00
175 INT154094 Negative_regulation of Eae1 25 0.18 30.42 7.89 5.00
176 INT157959 Binding of AQP4 32 0.48 43.44 7.44 5.00
177 INT173537 Binding of CCL16 18 0.40 13.02 7.36 5.00
178 INT102548 Negative_regulation of Ccr2 14 0.59 19.84 7.22 5.00
179 INT153271 Localization of Ccl3 7 0.81 11.29 7.14 5.00
180 INT153268 Positive_regulation of Ccr5 25 0.66 19 7.02 5.00
181 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92 5.00
182 INT5864 Localization of IL36RN 19 0.44 14.5 6.87 5.00
183 INT181348 Localization of Ccl5 24 0.65 19.55 6.8 5.00
184 INT140170 Binding of Nqo1 24 0.38 36.16 6.79 5.00
185 INT181382 Gene_expression of Ccl25 2 0.74 10.94 6.56 5.00
186 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 5.00
187 INT116398 Gene_expression of Mog 25 0.77 23.11 6.33 5.00
188 INT120089 Negative_regulation of Ccr5 7 0.58 10.36 5.91 5.00
189 INT154093 Positive_regulation of Gene_expression of Eae1 23 0.20 26.08 5.84 5.00
190 INT181022 Binding of Ccr1 15 0.37 10.69 5.37 5.00
191 INT75831 Positive_regulation of Transcription of IL8 21 0.63 13.56 4.98 5.00
192 INT181362 Negative_regulation of Ccl5 21 0.40 15.63 4.96 5.00
193 INT161220 Binding of Ccl2 17 0.46 17.63 4.94 5.00
194 INT131152 Gene_expression of Cr1l 17 0.75 10.83 4.88 5.00
195 INT104391 Gene_expression of Tnpo1 12 0.65 9.61 4.87 5.00
196 INT181350 Gene_expression of Ccl7 12 0.61 14.25 4.87 5.00
197 INT176614 Positive_regulation of Gene_expression of Ccl5 20 0.59 16.2 4.81 5.00
198 INT146807 Localization of CCL18 17 0.78 11.8 4.79 5.00
199 INT153269 Binding of Ccl3 10 0.48 8.87 4.69 5.00
200 INT181395 Gene_expression of Ccl8 11 0.67 13.88 4.56 5.00
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