D:Chronic Wasting Disease

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pChart

Disease Term
Synonyms None
Documents 18
Hot Single Events 13
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Chronic Wasting Disease. They are ordered first by their relevance to Chronic Wasting Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT297246 Binding of Notch1 and Ncstn 1 0.04 0.32 0.07 5.00
2 INT297244 Regulation of Binding of Notch1 and Ncstn 1 0.05 0.32 0.07 5.00
3 INT268647 ATP2B3 Positive_regulation of Prnp 1 0.01 0.57 0 5.00
4 INT335952 Prnp Positive_regulation of can 1 0.17 0.58 0 5.00
5 INT297245 Prnp Positive_regulation of Notch1 1 0.21 0.73 0 5.00
6 INT268648 ATP2B3 Regulation of ATP2B3 Positive_regulation of Prnp 1 0.00 0.57 0 5.00
7 INT335950 Negative_regulation of Prnp Positive_regulation of can 1 0.16 0.59 0 5.00
8 INT335953 Binding of BCL2 and Bad 1 0.14 0.37 0 5.00
9 INT260518 Binding of Prnp and Gopc 2 0.13 1.06 0 5.00
10 INT335951 Binding of Bad and Tgif2lx1 1 0.00 0.37 0 5.00
11 INT268646 Prnp Positive_regulation of PRNP 1 0.08 0.42 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Chronic Wasting Disease. They are ordered first by their pain relevance and then by number of times they were reported in Chronic Wasting Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT69570 Binding of Prnp 75 0.48 44.26 4.37 99.96
2 INT271855 Gene_expression of PR@ 11 0.06 11.07 0.61 99.62
3 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5 99.04
4 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34 99.04
5 INT135040 Regulation of Gene_expression of Prnp 30 0.62 10.52 2.45 98.92
6 INT271856 Positive_regulation of Positive_regulation of PR@ 1 0.02 1 0 97.08
7 INT239100 Positive_regulation of PR@ 4 0.37 8.28 2.73 96.00
8 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 93.48
9 INT102255 Regulation of Prnp 35 0.62 18.97 3.25 91.68
10 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11 91.12
11 INT255619 Regulation of CASZ1 2 0.03 0.9 0.06 86.44
12 INT259802 Positive_regulation of Tbx15 2 0.45 1.87 0.09 83.60
13 INT204737 Negative_regulation of Gene_expression of Prnp 32 0.59 18.96 1.03 80.92
14 INT315418 Negative_regulation of Slc26a5 1 0.01 0.63 0 78.80
15 INT335642 Positive_regulation of Atp2b2 1 0.03 0.59 0 68.76
16 INT102253 Negative_regulation of Prnp 75 0.59 24.23 2.62 61.44
17 INT69572 Localization of Prnp 96 0.81 38.11 5.45 60.36
18 INT268161 Regulation of Negative_regulation of Prnp 2 0.39 0.33 0 60.24
19 INT1653 Positive_regulation of DSP 8 0.49 3.3 2.93 43.64
20 INT194066 Gene_expression of Omp 6 0.34 2.28 0.12 41.52
21 INT102254 Positive_regulation of Gene_expression of Prnp 72 0.70 38.11 4.81 41.44
22 INT11021 Gene_expression of Tme 12 0.52 8.54 0.33 38.96
23 INT69571 Positive_regulation of Positive_regulation of Prnp 6 0.70 5.88 0.67 36.36
24 INT178338 Gene_expression of Tbx15 50 0.65 38.65 12.19 30.72
25 INT136634 Transcription of Prnp 9 0.72 3.34 0.83 25.00
26 INT306135 Localization of Omp 1 0.22 2.13 0 25.00
27 INT190664 Regulation of Binding of Prnp 3 0.52 4.29 0.1 19.44
28 INT190666 Positive_regulation of Binding of Prnp 2 0.50 1.87 0 19.44
29 INT2038 Localization of Esr1 104 0.79 40.12 13.27 16.92
30 INT100601 Localization of PRNP 17 0.66 13.61 0.71 15.72
31 INT29144 Gene_expression of Rvm 41 0.52 29.23 47.76 9.44
32 INT87765 Binding of Acot1 4 0.07 2.59 0.95 7.92
33 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
34 INT65500 Gene_expression of App 605 0.78 429.94 98.31 5.00
35 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26 5.00
36 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77 5.00
37 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
38 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39 5.00
39 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
40 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
41 INT173693 Localization of Gopc 249 0.65 70.49 38.81 5.00
42 INT47712 Positive_regulation of App 135 0.69 101.38 28.94 5.00
43 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 5.00
44 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28 5.00
45 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
46 INT23564 Negative_regulation of Car2 103 0.50 27.28 21.86 5.00
47 INT1561 Negative_regulation of Dnahc8 59 0.59 18.12 20.99 5.00
48 INT62577 Negative_regulation of Creb1 55 0.59 19.68 18.1 5.00
49 INT17237 Regulation of Esr1 74 0.43 49.09 17.25 5.00
50 INT71363 Binding of Rvm 9 0.31 3.23 10.83 5.00
51 INT121796 Gene_expression of NeuN 92 0.78 23.18 10.53 5.00
52 INT9385 Localization of LDHA 74 0.81 31.67 10.5 5.00
53 INT3982 Gene_expression of Acot1 53 0.56 7.61 10.46 5.00
54 INT200874 Positive_regulation of Localization of Gopc 27 0.38 5.69 7.5 5.00
55 INT13385 Gene_expression of Bad 60 0.76 41.86 6.52 5.00
56 INT160853 Gene_expression of Syp 87 0.72 20.06 5.31 5.00
57 INT121866 Localization of Creb1 13 0.73 1.95 4.48 5.00
58 INT3722 Negative_regulation of Acot1 19 0.42 4.88 4.21 5.00
59 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54 5.00
60 INT58527 Gene_expression of Prtn3 20 0.71 15.99 2.9 5.00
61 INT143591 Binding of NeuN 10 0.31 2.23 2.22 5.00
62 INT50057 Regulation of Notch1 3 0.39 0.87 2.14 5.00
63 INT172874 Phosphorylation of Bad 31 0.80 27.46 2.07 5.00
64 INT167203 Binding of PRNP 25 0.48 20.09 1.84 5.00
65 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84 5.00
66 INT183402 Positive_regulation of Gene_expression of Tbx15 7 0.49 4.87 1.62 5.00
67 INT222089 Positive_regulation of Localization of Esr1 19 0.49 8.73 1.58 5.00
68 INT22785 Negative_regulation of PRNP 12 0.57 5.09 1.57 5.00
69 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57 5.00
70 INT5855 Positive_regulation of Bad 12 0.61 12.26 1.56 5.00
71 INT141131 Positive_regulation of Gene_expression of PRNP 12 0.61 16.6 1.36 5.00
72 INT95694 Gene_expression of Chrnb1 6 0.36 4.27 1.33 5.00
73 INT170900 Regulation of Positive_regulation of Gopc 10 0.20 3.44 1.24 5.00
74 INT85621 Regulation of PRNP 16 0.60 8.7 1.15 5.00
75 INT245514 Regulation of Gene_expression of Tbx15 3 0.01 2.83 0.98 5.00
76 INT87768 Binding of Chrnb1 4 0.26 0.18 0.94 5.00
77 INT185973 Negative_regulation of Syp 16 0.54 2.83 0.87 5.00
78 INT70019 Binding of BCL2 25 0.47 17.55 0.79 5.00
79 INT201628 Positive_regulation of Gene_expression of Bad 12 0.68 13.86 0.72 5.00
80 INT190662 Regulation of Positive_regulation of Prnp 4 0.24 1.15 0.7 5.00
81 INT190667 Binding of PNMA2 1 0.08 2.37 0.66 5.00
82 INT193863 Gene_expression of Ncstn 7 0.29 3.88 0.66 5.00
83 INT131891 Localization of Cabin1 2 0.05 1.43 0.59 5.00
84 INT237402 Positive_regulation of Gene_expression of Ncstn 3 0.26 2.78 0.48 5.00
85 INT124164 Protein_catabolism of Prnp 20 1.00 8.58 0.44 5.00
86 INT306136 Binding of Tme 3 0.14 2.32 0.32 5.00
87 INT38147 Positive_regulation of Mixl1 3 0.26 1.31 0.32 5.00
88 INT301480 Positive_regulation of Sha 3 0.23 1.83 0.3 5.00
89 INT251949 Negative_regulation of Gene_expression of PRNP 6 0.43 4.16 0.3 5.00
90 INT335949 Positive_regulation of Positive_regulation of PRNP 2 0.25 0.82 0.29 5.00
91 INT229518 Phosphorylation of Prnp 5 0.69 1.62 0.27 5.00
92 INT69568 Positive_regulation of Localization of Prnp 5 0.50 2.43 0.26 5.00
93 INT268171 Negative_regulation of Binding of Prnp 3 0.42 0.82 0.25 5.00
94 INT208405 Gene_expression of Scamp3 2 0.29 0.87 0.24 5.00
95 INT297236 Negative_regulation of Gsi1 1 0.06 0.92 0.22 5.00
96 INT160670 Negative_regulation of Pdia3 3 0.42 0.7 0.22 5.00
97 INT190665 Gene_expression of Mixl1 4 0.35 2.54 0.2 5.00
98 INT297241 Positive_regulation of Positive_regulation of Notch1 2 0.40 1.02 0.2 5.00
99 INT50730 Positive_regulation of can 2 0.30 5.37 0.19 5.00
100 INT335938 Negative_regulation of can 1 0.25 4.91 0.17 5.00
101 INT297239 Positive_regulation of Gene_expression of Notch1 2 0.40 1.31 0.13 5.00
102 INT297240 Gene_expression of Gsi1 1 0.09 2.38 0.11 5.00
103 INT335935 Regulation of can 1 0.12 1.2 0.09 5.00
104 INT207304 Positive_regulation of Protein_catabolism of Prnp 9 0.69 2.08 0.09 5.00
105 INT335945 Phosphorylation of can 1 0.35 0.16 0.09 5.00
106 INT273338 Protein_catabolism of Apex1 4 0.05 0.57 0.09 5.00
107 INT303459 Transcription of PRNP 4 0.69 1.44 0.08 5.00
108 INT229516 Negative_regulation of Positive_regulation of Prnp 5 0.42 0.95 0.04 5.00
109 INT275621 Positive_regulation of Atcay 3 0.06 2.15 0.04 5.00
110 INT229519 Regulation of Localization of Prnp 4 0.61 0.7 0.03 5.00
111 INT208407 Binding of NGLY1 2 0.36 0.52 0.03 5.00
112 INT306134 Transcription of Omp 1 0.20 0.31 0 5.00
113 INT306133 Binding of Omp 1 0.11 0.48 0 5.00
114 INT297242 Transcription of Notch1 1 0.19 0.25 0 5.00
115 INT335943 Regulation of Negative_regulation of can 1 0.12 0.22 0 5.00
116 INT335941 Gene_expression of Cabin1 1 0.04 0.38 0 5.00
117 INT335939 Positive_regulation of Negative_regulation of can 1 0.21 0.8 0 5.00
118 INT276900 Positive_regulation of Tme 3 0.28 2.33 0 5.00
119 INT196207 Negative_regulation of Tbx15 2 0.42 0.86 0 5.00
120 INT194072 Positive_regulation of Gene_expression of Omp 5 0.25 0.34 0 5.00
121 INT297243 Transcription of Ncstn 1 0.22 0.12 0 5.00
122 INT297237 Positive_regulation of Transcription of Ncstn 1 0.16 0.13 0 5.00
123 INT335944 Localization of can 1 0.13 0.3 0 5.00
124 INT297238 Binding of Gsi1 1 0.05 0.5 0 5.00
125 INT335942 Positive_regulation of Cabin1 1 0.05 1.5 0 5.00
126 INT208404 Gene_expression of Scamp4 1 0.75 1.02 0 5.00
127 INT335946 Positive_regulation of Positive_regulation of Cabin1 1 0.03 0.64 0 5.00
128 INT190663 Binding of Mixl1 1 0.19 1.08 0 5.00
129 INT335934 Negative_regulation of Cabin1 1 0.04 0.98 0 5.00
130 INT240690 Positive_regulation of Binding of PRNP 1 0.07 0.53 0 5.00
131 INT306132 Localization of Tme 1 0.23 0.48 0 5.00
132 INT335936 Regulation of Negative_regulation of Cabin1 1 0.03 0.98 0 5.00
133 INT268645 Positive_regulation of ATP2B3 1 0.01 0.15 0 5.00
134 INT240689 Gene_expression of FCMTE1 3 0.15 1.31 0 5.00
135 INT335937 Negative_regulation of Phosphorylation of Bad 1 0.15 0.41 0 5.00
136 INT208408 Negative_regulation of NGLY1 1 0.41 0.23 0 5.00
137 INT335940 Binding of can 1 0.16 0.43 0 5.00
138 INT315419 Protein_catabolism of Chrnb1 1 0.03 0.14 0 5.00
139 INT315417 Negative_regulation of Transcription of Prnp 1 0.43 0.14 0 5.00
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