D:Chylothorax

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Disease Term
Synonyms None
Documents 91
Hot Single Events 3
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Chylothorax. They are ordered first by their relevance to Chylothorax and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT272012 Binding of TSC1 and Lsamp 1 0.03 2.1 0.08 86.72
2 INT272018 Binding of TSC1 and Tsc2 1 0.17 0.48 0 22.80
3 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 5.00
4 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 5.00
5 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12 5.00
6 INT272006 Binding of YWHAQ and Tsc2 1 0.27 0.39 0.1 5.00
7 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07 5.00
8 INT272003 Binding of Tsc2 and Tsc1 1 0.18 1.1 0.07 5.00
9 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07 5.00
10 INT272009 Binding of YWHAQ and Tsc1 1 0.37 0.14 0.03 5.00
11 INT271990 Tsc1 Positive_regulation of Tsc2 1 0.36 0.31 0 5.00
12 INT271996 Binding of Plk1 and Tsc1 1 0.09 0.32 0 5.00
13 INT331611 NKX2-1 Regulation of Transcription of SFTPB 1 0.01 0.49 0 5.00
14 INT271991 Tsc1 Regulation of Tsc2 1 0.23 0.15 0 5.00
15 INT272015 Pkd1 Positive_regulation of Localization of TSC1 1 0.18 0.65 0 5.00
16 INT272017 TBC1D7 Positive_regulation of Protein_catabolism of Tsc1 1 0.08 0.46 0 5.00
17 INT271982 Binding of Skp2 and Psmd9 1 0.01 0.68 0 5.00
18 INT272013 Binding of OGG1 and Tsc2 1 0.09 0.67 0 5.00
19 INT272010 Tsc2 Negative_regulation of OGG1 1 0.17 0.6 0 5.00
20 INT271966 Phosphorylation of Rasa1 Positive_regulation of Tsc2 1 0.01 0.31 0 5.00
21 INT272000 Binding of Skp2 and Hecw1 1 0.01 0.11 0 5.00
22 INT271985 Tsc1 Regulation of Cdkn1b 1 0.04 0.1 0 5.00
23 INT271979 Skp2 Positive_regulation of Protein_catabolism of Psmd9 1 0.01 0.35 0 5.00
24 INT272008 Tsc1 Negative_regulation of Binding of HERC1 1 0.01 0.32 0 5.00
25 INT272014 Binding of RB1CC1 and Tsc1 1 0.05 0.44 0 5.00
26 INT272016 Mtor Negative_regulation of INS 1 0.00 0.61 0 5.00
27 INT271997 Binding of Cdk1 and Plk1 1 0.03 0.3 0 5.00
28 INT271999 Binding of Fkbp1a and Positive_regulation of Negative_regulation of Mtor 1 0.00 0.18 0 5.00
29 INT271984 Binding of Tsc2 and Skp2 1 0.06 0.34 0 5.00
30 INT272011 Binding of RAB5A and Tsc2 1 0.02 0.16 0 5.00
31 INT272004 Binding of Hspa1b and Tsc2 1 0.01 0.45 0 5.00
32 INT271983 Binding of Tsc2 and Rap1a 1 0.02 0.16 0 5.00
33 INT271994 Binding of Fkbp1a and Mtor 1 0.00 0.22 0 5.00
34 INT272005 Phosphorylation of Tsc1 Regulation of Binding of Cdk1 and Plk1 1 0.02 0.3 0 5.00
35 INT271989 Binding of Tsc2 and Psmd9 1 0.02 0.47 0 5.00
36 INT272007 Binding of Tsc2 and SCPEP1 1 0.27 0.46 0 5.00
37 INT271998 Cdk1 Positive_regulation of Phosphorylation of Tsc1 1 0.17 0.3 0 5.00
38 INT271978 Positive_regulation of Racgap1 Regulation of Mtor 1 0.00 0.54 0 5.00
39 INT271987 Tsc2 Regulation of Skp2 1 0.10 0.28 0 5.00
40 INT271986 Tsc1 Regulation of Skp2 1 0.13 0.14 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Chylothorax. They are ordered first by their pain relevance and then by number of times they were reported in Chylothorax. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 98.64
2 INT221269 Binding of BRCA1 14 0.40 31.77 2.7 98.16
3 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 89.92
4 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 75.40
5 INT84541 Binding of Tapbp 3 0.31 2.21 0.29 50.00
6 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 45.80
7 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56 39.04
8 INT271930 Gene_expression of Tsc1 1 0.69 6.88 0.04 32.16
9 INT119227 Gene_expression of Tsc2 8 0.68 10.67 0.03 31.04
10 INT319739 Negative_regulation of Psgb1 1 0.22 0.29 0.17 25.80
11 INT246776 Negative_regulation of Tsc2 18 0.48 6.82 0.12 12.96
12 INT271914 Negative_regulation of Tsc1 5 0.38 3.08 0.04 12.96
13 INT271931 Negative_regulation of Gene_expression of Tsc1 1 0.38 0.44 0 12.96
14 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
15 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
16 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
17 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
18 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
19 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
20 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 5.00
21 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
22 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
23 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
24 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
25 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
26 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43 5.00
27 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
28 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 5.00
29 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 5.00
30 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 5.00
31 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29 5.00
32 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 5.00
33 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 5.00
34 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 5.00
35 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
36 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 5.00
37 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74 5.00
38 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15 5.00
39 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 5.00
40 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69 5.00
41 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28 5.00
42 INT19185 Negative_regulation of Cd4 80 0.51 61.32 8.51 5.00
43 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 5.00
44 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 5.00
45 INT89104 Binding of TGFB1 29 0.44 13.67 5.12 5.00
46 INT120073 Positive_regulation of Itk 34 0.44 23.45 5.09 5.00
47 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 5.00
48 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37 5.00
49 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21 5.00
50 INT123411 Gene_expression of Sp1 15 0.69 4.2 3.79 5.00
51 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6 5.00
52 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2 5.00
53 INT38013 Gene_expression of Casr 30 0.73 6.03 3.09 5.00
54 INT32421 Gene_expression of FCER2 19 0.73 17.23 2.53 5.00
55 INT158442 Gene_expression of Nkx2-1 21 0.59 8.47 1.99 5.00
56 INT90377 Gene_expression of HBA1 26 0.75 7.34 1.51 5.00
57 INT214073 Binding of TSC1 9 0.37 22 1.34 5.00
58 INT120075 Gene_expression of Itk 11 0.43 6.39 1.27 5.00
59 INT167283 Negative_regulation of Phosphorylation of Gsk3b 12 0.59 7.94 1.16 5.00
60 INT160576 Gene_expression of Psgb1 3 0.35 1.63 1.08 5.00
61 INT67097 Gene_expression of MIB1 20 0.75 21.06 1.03 5.00
62 INT15040 Gene_expression of NKX2-1 8 0.65 3.95 1.02 5.00
63 INT151774 Positive_regulation of Mtor 38 0.45 20.15 1.01 5.00
64 INT23030 Positive_regulation of Pth 13 0.61 9.24 0.97 5.00
65 INT199345 Gene_expression of Lyve1 11 0.50 8.44 0.89 5.00
66 INT126523 Phosphorylation of Mapkapk2 19 0.79 7.76 0.82 5.00
67 INT169706 Positive_regulation of Gene_expression of Itk 2 0.32 2.08 0.81 5.00
68 INT74019 Regulation of TSC1 27 0.35 23.61 0.79 5.00
69 INT271917 Phosphorylation of Mtor 11 0.13 6.76 0.78 5.00
70 INT129174 Gene_expression of PKD1 24 0.67 14.91 0.74 5.00
71 INT184694 Gene_expression of Usf1 10 0.55 4.27 0.72 5.00
72 INT114909 Negative_regulation of Localization of TGFB1 5 0.36 1.37 0.66 5.00
73 INT44080 Positive_regulation of HBA1 7 0.25 2.23 0.6 5.00
74 INT71497 Binding of Hspa1b 3 0.08 1.43 0.58 5.00
75 INT182435 Localization of OGG1 36 0.76 1.66 0.58 5.00
76 INT271939 Regulation of Tsc1 2 0.41 1.16 0.47 5.00
77 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45 5.00
78 INT247798 Negative_regulation of Rasa1 3 0.09 1.05 0.44 5.00
79 INT230653 Phosphorylation of Rasa1 3 0.55 0.6 0.42 5.00
80 INT271922 Phosphorylation of Cdk1 2 0.44 0.37 0.39 5.00
81 INT184803 Localization of TSC1 5 0.37 6.13 0.32 5.00
82 INT186450 Negative_regulation of SFTPB 17 0.58 10.94 0.31 5.00
83 INT317746 Positive_regulation of Gene_expression of FCER2 2 0.01 4.09 0.3 5.00
84 INT125804 Localization of Pth 9 0.69 3.93 0.29 5.00
85 INT126522 Positive_regulation of Phosphorylation of Mapkapk2 7 0.59 3.8 0.28 5.00
86 INT190676 Binding of Fkbp1a 15 0.36 3.11 0.28 5.00
87 INT70144 Gene_expression of Sry 4 0.63 1.15 0.28 5.00
88 INT241240 Gene_expression of Pkd1 18 0.54 12.2 0.27 5.00
89 INT246762 Phosphorylation of Tsc2 60 0.67 15.71 0.25 5.00
90 INT275892 Positive_regulation of Gene_expression of HBA1 7 0.67 2.4 0.24 5.00
91 INT299545 Positive_regulation of Binding of TGFB1 2 0.06 1.08 0.22 5.00
92 INT182413 Binding of OGG1 17 0.46 2.44 0.22 5.00
93 INT271929 Protein_catabolism of Psmd9 4 0.11 1.69 0.21 5.00
94 INT239883 Transcription of SFTPC 3 0.69 1.11 0.18 5.00
95 INT179044 Regulation of Cdkn1b 4 0.22 2.64 0.18 5.00
96 INT192842 Binding of Hspa5 3 0.33 1.48 0.16 5.00
97 INT231230 Localization of SFTPC 2 0.68 2.06 0.16 5.00
98 INT271943 Phosphorylation of Tsc2 9 0.52 3.35 0.13 5.00
99 INT271573 Binding of SCPEP1 3 0.35 1.21 0.13 5.00
100 INT246749 Negative_regulation of Phosphorylation of Tsc2 11 0.35 3.4 0.12 5.00
101 INT271941 Binding of Tsc2 12 0.24 2.96 0.11 5.00
102 INT146139 Gene_expression of ETV4 11 0.12 8.43 0.11 5.00
103 INT320983 Negative_regulation of Localization of Pth 2 0.38 1.17 0.09 5.00
104 INT331623 Negative_regulation of Binding of TGFB1 1 0.02 1.02 0.08 5.00
105 INT271938 Binding of Tsc1 1 0.43 3.18 0.07 5.00
106 INT331613 Regulation of Positive_regulation of Itk 1 0.02 0.87 0.06 5.00
107 INT331615 Binding of Igbp1 1 0.00 0.95 0.05 5.00
108 INT211006 Binding of PKD1 6 0.22 2.69 0.05 5.00
109 INT197280 Regulation of Psmd9 2 0.07 0.1 0.05 5.00
110 INT271916 Positive_regulation of Phosphorylation of Tsc2 4 0.32 0.52 0.04 5.00
111 INT271937 Positive_regulation of Binding of Tsc2 1 0.25 0 0.04 5.00
112 INT271960 Positive_regulation of Binding of TSC1 1 0.25 0.88 0.03 5.00
113 INT249790 Protein_catabolism of Skp2 2 0.58 1.02 0.03 5.00
114 INT191542 Binding of ABCA3 1 0.22 1.61 0.03 5.00
115 INT271964 Binding of HERC1 1 0.01 0.31 0 5.00
116 INT271935 Positive_regulation of Phosphorylation of Rps6 1 0.02 0.17 0 5.00
117 INT271924 Positive_regulation of Protein_catabolism of Psmd9 1 0.05 0.35 0 5.00
118 INT271905 Positive_regulation of Protein_catabolism of Tsc2 1 0.35 1.46 0 5.00
119 INT271965 Negative_regulation of Binding of TSC1 1 0.33 0.44 0 5.00
120 INT271921 Negative_regulation of Tsc2 2 0.26 1.19 0 5.00
121 INT271928 Binding of Plk1 1 0.07 0.29 0 5.00
122 INT271904 Localization of Tsc2 1 0.41 1.31 0 5.00
123 INT246774 Positive_regulation of Tsc2 6 0.41 2.4 0 5.00
124 INT228895 Binding of Tsc2 5 0.30 2.41 0 5.00
125 INT271936 Phosphorylation of Tsc1 4 0.73 1.76 0 5.00
126 INT246755 Regulation of Tsc2 4 0.50 1.01 0 5.00
127 INT161700 Positive_regulation of Psmd9 3 0.59 0.41 0 5.00
128 INT271919 Gene_expression of Tsc2 6 0.39 2.23 0 5.00
129 INT271962 Localization of SLC7A6 1 0.73 0.08 0 5.00
130 INT242456 Binding of Cdk2 2 0.16 1.29 0 5.00
131 INT271913 Protein_catabolism of Tsc1 1 0.51 0.45 0 5.00
132 INT271940 Protein_catabolism of Tsc2 1 0.50 0.7 0 5.00
133 INT271906 Negative_regulation of Binding of Tsc1 1 0.38 0.06 0 5.00
134 INT182417 Positive_regulation of OGG1 2 0.44 0.83 0 5.00
135 INT298953 Positive_regulation of Gene_expression of Lyve1 1 0.03 0.77 0 5.00
136 INT214045 Negative_regulation of OGG1 5 0.36 3.49 0 5.00
137 INT331624 Transcription of SFTPB 1 0.03 0.48 0 5.00
138 INT271944 Negative_regulation of Phosphorylation of Tsc2 2 0.30 0.42 0 5.00
139 INT271927 Positive_regulation of Tsc1 1 0.44 0.4 0 5.00
140 INT271903 Positive_regulation of Protein_catabolism of Skp2 1 0.14 0.47 0 5.00
141 INT271910 Gene_expression of Hsf2 4 0.45 1.63 0 5.00
142 INT271920 Negative_regulation of Protein_catabolism of Skp2 1 0.12 0.37 0 5.00
143 INT246761 Positive_regulation of Gene_expression of Tsc2 2 0.41 1.17 0 5.00
144 INT271934 Binding of Psmd9 1 0.03 0.66 0 5.00
145 INT271923 Regulation of Binding of Plk1 1 0.09 0.29 0 5.00
146 INT271963 Phosphorylation of TSC1 2 0.31 2.02 0 5.00
147 INT271907 Phosphorylation of Rps6 4 0.09 0.67 0 5.00
148 INT271915 Negative_regulation of Pkd1 8 0.36 6.44 0 5.00
149 INT271926 Negative_regulation of Protein_catabolism of Psmd9 1 0.04 0.37 0 5.00
150 INT331625 Negative_regulation of ABCA3 1 0.27 0.38 0 5.00
151 INT271961 Phosphorylation of PRKD1 1 0.02 0.6 0 5.00
152 INT271909 Positive_regulation of Tsc2 1 0.25 0.06 0 5.00
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