D:Cicatrix

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pChart

Disease Term
Synonyms Cicatrices, Scar, Scars
Documents 3171
Hot Single Events 200
Hot Interactions 13

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cicatrix. They are ordered first by their relevance to Cicatrix and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT208459 Galns Negative_regulation of Negative_regulation of BCAN 1 0.01 0.44 0.13 99.16
2 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08 98.64
3 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08 98.64
4 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08 98.64
5 INT355021 Cntf Positive_regulation of SOAT1 1 0.02 0.7 0.08 98.32
6 INT355022 Cntf Positive_regulation of JAK1 1 0.00 0.69 0.08 98.32
7 INT355009 Cntf Positive_regulation of Il6st 1 0.02 0.69 0.08 98.32
8 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97 97.52
9 INT355018 Binding of FAS and Faslg 1 0.12 1.34 0.37 94.04
10 INT242847 Binding of CDB2 and TGFBI 1 0.17 0.56 0 88.04
11 INT294205 Serpine1 Negative_regulation of Plat 1 0.47 0.51 0 85.20
12 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96 83.28
13 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88 81.56
14 INT318099 Binding of Ldha and Ppia 1 0.36 0.66 0 76.08
15 INT318102 Binding of RPL5 and Ldha 1 0.08 0.66 0 75.72
16 INT355023 Phosphorylation of Rtn4r Negative_regulation of Binding of Mag and Rtn4r 1 0.00 0.38 0.11 75.36
17 INT323926 MRM1 Positive_regulation of MRI1 1 0.04 0.44 0.26 74.88
18 INT355881 Il17a Regulation of Gene_expression of Hand1 1 0.18 1.51 0.54 74.56
19 INT355878 Il17a Regulation of Eae1 1 0.06 1.52 0.54 74.56
20 INT355880 Il17a Regulation of Abi3 1 0.00 1.52 0.54 74.56
21 INT213749 NHS Positive_regulation of Localization of CALM1 1 0.28 0.58 0.14 71.40
22 INT355008 Binding of Mag and Rtn4r 1 0.02 0.36 0.1 69.60
23 INT254232 Binding of Tlr4 and TRAM1 2 0.07 1.11 0 68.56
24 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11 68.40
25 INT286110 Binding of Rpe65 and Gopc 1 0.01 1.97 0 66.40
26 INT286113 Binding of Fap and Rpe65 1 0.04 1.97 0 66.00
27 INT303440 Egf Positive_regulation of Gene_expression of Col7a1 1 0.07 0.92 0.28 65.28
28 INT349646 Eif2ak1 Regulation of Gene_expression of Hmox1 1 0.00 0.78 0.2 62.88
29 INT246360 Binding of Cea and Muc6 1 0.00 1.09 0.12 61.84
30 INT246362 Binding of MUC2 and Cea 1 0.00 1.08 0.12 61.84
31 INT300446 VEGFA Positive_regulation of Flt1 1 0.09 2.62 0.07 59.40
32 INT300445 VEGFA Positive_regulation of Vegfa 1 0.03 1.33 0.03 59.40
33 INT303439 Egf Positive_regulation of Gene_expression of Fn1 1 0.05 0.82 0 54.88
34 INT332248 Ccl2 Positive_regulation of Ctgf 1 0.04 1.13 0.42 53.68
35 INT170817 CMA1 Positive_regulation of Gene_expression of AGT 1 0.19 1.41 0.14 51.16
36 INT323077 CPOX Negative_regulation of Gene_expression of Ptger2 1 0.00 1.57 1.05 50.00
37 INT284705 CMA1 Positive_regulation of Gene_expression of COL7A1 1 0.04 0.49 0.05 50.00
38 INT342559 FGF2 Positive_regulation of MAPK1 1 0.08 1.22 0 44.84
39 INT342557 FGF2 Positive_regulation of MAPK3 1 0.03 1.21 0 44.84
40 INT342558 FGF9 Positive_regulation of MAPK3 1 0.03 1.21 0 44.60
41 INT342555 FGF9 Positive_regulation of MAPK1 1 0.07 1.22 0 44.60
42 INT347123 Binding of Axin2 and Lrp1 1 0.08 0.2 0 42.44
43 INT240410 Gene_expression of CD69 Positive_regulation of CD8A 1 0.10 0 0 42.24
44 INT347124 Binding of FZD1 and Lrp1 1 0.11 0.24 0 40.96
45 INT215766 Dio1 Regulation of Cdk6 1 0.01 0.05 0 39.12
46 INT215764 Dio1 Regulation of Ces1c 1 0.00 0.05 0 39.12
47 INT215768 Dio1 Regulation of Cdk4 1 0.01 0.05 0 39.12
48 INT215685 Slc3a1 Regulation of Ces1c 1 0.00 0.05 0 38.96
49 INT215701 Slc3a1 Regulation of Cdk6 1 0.01 0.05 0 38.96
50 INT215709 Slc3a1 Regulation of Cdk4 1 0.01 0.05 0 38.96
51 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65 38.20
52 INT206621 Col1a1 Positive_regulation of Col3a1 1 0.00 0.28 0 37.76
53 INT272024 Gene_expression of GOPC Positive_regulation of Localization of COL7A1 1 0.10 0.86 0.14 35.24
54 INT299158 Binding of Lgals3 and Renbp 1 0.00 0.64 0.11 34.28
55 INT270789 CRP Negative_regulation of Gene_expression of TNF 1 0.34 0.87 0.36 32.00
56 INT300449 VEGFA Positive_regulation of Protein_catabolism of Ppp2r2b 1 0.00 1.51 0.05 31.24
57 INT349652 Positive_regulation of Hmox1 Negative_regulation of Positive_regulation of Itk 1 0.01 0.85 0.25 30.12
58 INT349653 Nfe2l2 Positive_regulation of Itk 1 0.00 0.79 0.22 28.24
59 INT294208 Gene_expression of Serpine1 Negative_regulation of Plat 1 0.47 0.94 0.12 26.88
60 INT294204 Binding of Serpine1 and Plat 1 0.46 0.2 0 26.00
61 INT285949 IL6 Positive_regulation of Gene_expression of IL17A 1 0.14 0.23 0 25.28
62 INT344832 Hmgb1 Positive_regulation of Gene_expression of Nos2 1 0.12 0.82 0.17 23.20
63 INT337915 Tgfbr1 Positive_regulation of Negative_regulation of Smad2 1 0.05 0.15 0 22.12
64 INT337918 sb Positive_regulation of Negative_regulation of Smad2 1 0.00 0.15 0 21.48
65 INT215707 Cdkn2a Negative_regulation of Cdkn1b 1 0.01 0 0 19.68
66 INT215699 Cdkn2a Negative_regulation of Cdkn1c 1 0.01 0 0 19.68
67 INT215696 Cdkn2a Negative_regulation of Kras 1 0.00 0 0 19.68
68 INT215686 Cdkn2b Negative_regulation of Cdkn1c 1 0.01 0 0 19.48
69 INT215700 Binding of Cdkn2b and Cdk6 1 0.02 0 0 19.48
70 INT215778 Lamtor1 Negative_regulation of Binding of Cdkn2b and Cdk6 1 0.01 0 0 19.48
71 INT215774 Cdkn2b Negative_regulation of Binding of Cdkn1b and Cdk6 1 0.00 0 0 19.48
72 INT215777 Cdkn2b Negative_regulation of Binding of Cdkn2b and Cdk6 1 0.00 0 0 19.48
73 INT215773 Cdkn2b Negative_regulation of Binding of Cdk6 and Cdkn1c 1 0.00 0 0 19.48
74 INT215780 Cdkn2b Negative_regulation of Binding of Cdk6 and Lamtor1 1 0.01 0 0 19.48
75 INT215688 Cdkn2b Negative_regulation of Kras 1 0.00 0 0 19.48
76 INT215694 Cdkn2b Negative_regulation of Cdkn1b 1 0.01 0 0 19.48
77 INT215781 Cdkn2b Negative_regulation of Binding of Kras and Cdk6 1 0.00 0 0 19.48
78 INT215698 Lamtor1 Negative_regulation of Kras 1 0.00 0 0 19.28
79 INT215706 Binding of Cdk6 and Lamtor1 1 0.04 0 0 19.28
80 INT215697 Lamtor1 Negative_regulation of Cdkn1b 1 0.02 0 0 19.28
81 INT215776 Lamtor1 Negative_regulation of Binding of Kras and Cdk6 1 0.00 0 0 19.28
82 INT215695 Lamtor1 Negative_regulation of Cdkn1c 1 0.02 0 0 19.28
83 INT215782 Lamtor1 Negative_regulation of Binding of Cdkn1b and Cdk6 1 0.01 0 0 19.28
84 INT215779 Lamtor1 Negative_regulation of Binding of Cdk6 and Lamtor1 1 0.01 0 0 19.28
85 INT215775 Lamtor1 Negative_regulation of Binding of Cdk6 and Cdkn1c 1 0.01 0 0 19.28
86 INT215702 Stmn1 Negative_regulation of Kras 1 0.00 0 0 18.92
87 INT215704 Stmn1 Negative_regulation of Cdkn1c 1 0.00 0 0 18.92
88 INT215692 Stmn1 Negative_regulation of Cdkn1b 1 0.00 0 0 18.92
89 INT215690 Binding of Cdk6 and Cdkn1c 1 0.03 0 0 17.52
90 INT215682 Binding of Cdkn1b and Cdk6 1 0.03 0 0 17.52
91 INT215703 Binding of Kras and Cdk6 1 0.01 0 0 17.52
92 INT345343 PTCH1 Regulation of Negative_regulation of SMO 1 0.09 2.3 0.13 17.16
93 INT228288 Binding of ENG and Ptprc 1 0.06 0.25 0 16.68
94 INT228285 Binding of Ptprc and Nt5e 1 0.06 0.25 0 16.68
95 INT228287 Binding of ENG and Cd14 1 0.20 0.25 0 16.44
96 INT228286 Binding of Cd14 and Nt5e 1 0.20 0.25 0 16.44
97 INT184192 IL1B Positive_regulation of SPAM1 1 0.04 0.49 0.24 15.36
98 INT298635 PPARA Negative_regulation of Localization of ZDHHC2 1 0.01 0.21 0.05 15.36
99 INT212078 Eno2 Regulation of Localization of EPHB6 1 0.03 0.52 0.07 10.24
100 INT212068 CHGA Regulation of Localization of EPHB6 1 0.49 0.52 0.07 10.24
101 INT212069 SYP Regulation of Localization of EPHB6 1 0.49 0.52 0.07 10.24
102 INT212066 ENO2 Regulation of Localization of EPHB6 1 0.49 0.52 0.07 10.24
103 INT212071 Eno2 Regulation of Localization of Afp 1 0.01 0.52 0.07 9.52
104 INT212079 SYP Regulation of Localization of Afp 1 0.10 0.52 0.07 9.52
105 INT212077 CHGA Regulation of Localization of Afp 1 0.10 0.52 0.07 9.52
106 INT212076 ENO2 Regulation of Localization of Afp 1 0.10 0.52 0.07 9.52
107 INT212070 ENO2 Regulation of Localization of AFP 1 0.49 0.52 0.07 9.12
108 INT212067 CHGA Regulation of Localization of AFP 1 0.49 0.52 0.07 9.12
109 INT212081 Eno2 Regulation of Localization of AFP 1 0.03 0.52 0.07 9.12
110 INT212062 SYP Regulation of Localization of AFP 1 0.49 0.52 0.07 9.12
111 INT212080 Eno2 Regulation of Localization of SYP 1 0.03 0.51 0.07 7.36
112 INT212063 CHGA Regulation of Localization of SYP 1 0.49 0.51 0.07 7.36
113 INT212064 ENO2 Regulation of Localization of SYP 1 0.49 0.51 0.07 7.36
114 INT269315 Binding of Crp and Gp6 1 0.03 0 0 7.20
115 INT344833 Binding of Ager and Hmgb1 1 0.08 0.72 0.22 5.76
116 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18 5.52
117 INT298637 ZDHHC2 Negative_regulation of Gene_expression of VEGFA 1 0.01 0.27 0.04 5.40
118 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
119 INT73539 Binding of Ngf and Ngfr 5 0.45 3.99 4 5.00
120 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 5.00
121 INT212301 NGF Regulation of Gene_expression of TRPV1 1 0.23 2.37 2.13 5.00
122 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
123 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64 5.00
124 INT229094 Binding of IL1RN and Il1r1 1 0.01 1.9 1.5 5.00
125 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35 5.00
126 INT209409 Binding of CALM1 and NHS 2 0.27 0.58 1.32 5.00
127 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3 5.00
128 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29 5.00
129 INT247924 Slc12a5 Regulation of Gene_expression of Slc12a2 1 0.25 1.43 1.23 5.00
130 INT247926 Slc12a5 Regulation of Cl 1 0.01 1.43 1.23 5.00
131 INT247925 Slc12a2 Regulation of Cl 1 0.01 1.44 1.23 5.00
132 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16 5.00
133 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13 5.00
134 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05 5.00
135 INT242642 Binding of BDNF and Ngfr 2 0.21 1.38 1.01 5.00
136 INT203040 Binding of PDCD1 and PDCD1LG2 3 0.40 4.86 0.98 5.00
137 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87 5.00
138 INT302379 Crp Positive_regulation of Gene_expression of Ccl2 1 0.10 4.58 0.84 5.00
139 INT256045 Binding of BDNF and Ntrk1 3 0.34 0.65 0.83 5.00
140 INT228054 Fpr3 Positive_regulation of Il10 1 0.05 0.9 0.79 5.00
141 INT289333 Binding of Ngfr and Rtn4r 1 0.03 2.35 0.72 5.00
142 INT289332 Binding of Ngfr and Lingo1 1 0.04 2.36 0.72 5.00
143 INT209250 TRPV1 Positive_regulation of Localization of DRGX 1 0.06 0.82 0.68 5.00
144 INT229085 IL1RN Negative_regulation of Positive_regulation of IL1R1 1 0.12 1.72 0.68 5.00
145 INT203046 Binding of PDCD1 and CD274 2 0.40 3.97 0.68 5.00
146 INT184120 Il4 Positive_regulation of Stat6 3 0.09 2.39 0.67 5.00
147 INT230336 IL4 Regulation of IL5 2 0.04 0.82 0.67 5.00
148 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66 5.00
149 INT184193 HRAS Negative_regulation of Gene_expression of IL1B 1 0.00 1.12 0.65 5.00
150 INT339794 Sstr2 Positive_regulation of Gene_expression of Sstr5 1 0.08 0.25 0.64 5.00
151 INT292893 TNF Regulation of IL8 2 0.27 1.3 0.63 5.00
152 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61 5.00
153 INT310712 Gabrg1 Positive_regulation of Gene_expression of PMP22 1 0.35 0.56 0.61 5.00
154 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61 5.00
155 INT139901 Ins1 Positive_regulation of Akt1 9 0.31 4.58 0.6 5.00
156 INT137141 Binding of HIVEP1 and ITIH4 2 0.16 1.44 0.56 5.00
157 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 5.00
158 INT112025 Binding of Hand1 and Il10 2 0.15 0.56 0.55 5.00
159 INT211993 Binding of Ppara and Rorb 1 0.00 1.13 0.54 5.00
160 INT310701 RPLP0 Regulation of Positive_regulation of PGR 1 0.01 0.49 0.53 5.00
161 INT285940 Binding of IL6 and IL17A 1 0.11 1.42 0.53 5.00
162 INT106744 Binding of CRP and EGFL7 2 0.07 2.35 0.51 5.00
163 INT195122 Il1 Positive_regulation of Gene_expression of Gtf3a 1 0.02 1.38 0.5 5.00
164 INT229095 Binding of IL1R1 and Il1r1 1 0.00 0.64 0.5 5.00
165 INT311963 Ifx Negative_regulation of FBN1 1 0.00 0.44 0.5 5.00
166 INT256040 Ngf Regulation of Gene_expression of Ntrk1 1 0.36 0.73 0.5 5.00
167 INT320451 ECT Positive_regulation of Gene_expression of BDNF 1 0.05 1.21 0.49 5.00
168 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48 5.00
169 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
170 INT310711 Binding of RPLP0 and Gabrg1 1 0.04 0.37 0.45 5.00
171 INT247639 Binding of Jun and Atf3 2 0.09 3.06 0.44 5.00
172 INT256042 Negative_regulation of Musk Negative_regulation of Ntrk1 1 0.08 0.48 0.44 5.00
173 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43 5.00
174 INT230437 Binding of PDX1 and HRCT1 1 0.04 2.45 0.43 5.00
175 INT276216 Binding of Akt1 and Ins1 2 0.03 2.61 0.4 5.00
176 INT292887 IL4 Regulation of IL12A 1 0.01 0.25 0.39 5.00
177 INT292891 IL2 Regulation of IL5 1 0.02 0.25 0.39 5.00
178 INT292892 IL4 Regulation of IL8 1 0.01 0.25 0.39 5.00
179 INT292889 IL2 Regulation of IL12A 1 0.01 0.25 0.39 5.00
180 INT292890 TNF Regulation of IL5 1 0.02 0.25 0.39 5.00
181 INT292888 TNF Regulation of IL12A 1 0.02 0.25 0.39 5.00
182 INT292886 IL2 Regulation of IL8 1 0.03 0.25 0.39 5.00
183 INT166792 Binding of CD44 and HRAS 3 0.12 1.49 0.37 5.00
184 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37 5.00
185 INT285935 IL6 Positive_regulation of Gene_expression of POU5F1 1 0.14 2.68 0.37 5.00
186 INT211492 Positive_regulation of GRIN1 Positive_regulation of Prkca 1 0.01 0.87 0.36 5.00
187 INT230438 Binding of PDX1 and HAUS7 1 0.02 2.29 0.35 5.00
188 INT272412 VSX1 Positive_regulation of Gene_expression of Slc11a1 1 0.00 0.57 0.35 5.00
189 INT183786 IL6 Negative_regulation of INS 1 0.09 1.61 0.35 5.00
190 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34 5.00
191 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34 5.00
192 INT183793 INS Negative_regulation of Binding of Ros1 1 0.16 1.66 0.34 5.00
193 INT183785 INS Positive_regulation of Gene_expression of NFKBIB 1 0.03 1.83 0.34 5.00
194 INT238261 pma Positive_regulation of Prkcg 1 0.01 0.33 0.34 5.00
195 INT183780 INS Negative_regulation of Gene_expression of CYBB 1 0.02 1.74 0.34 5.00
196 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 5.00
197 INT172004 IL17A Positive_regulation of Gene_expression of IL6 2 0.14 1.35 0.34 5.00
198 INT183782 INS Negative_regulation of Gene_expression of TBK1 1 0.01 1.81 0.34 5.00
199 INT256043 Binding of Ngfr and Positive_regulation of Binding of Ngf Ntrk1 1 0.17 0.28 0.33 5.00
200 INT229087 IL1R1 Negative_regulation of ACCS 1 0.03 0.86 0.33 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cicatrix. They are ordered first by their pain relevance and then by number of times they were reported in Cicatrix. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 100.00
2 INT219776 Negative_regulation of Hcls1 1 0.49 1.85 0.03 100.00
3 INT72149 Regulation of Cttn 3 0.31 0.95 0.76 100.00
4 INT219761 Negative_regulation of Wasf1 1 0.57 0.57 0 100.00
5 INT74484 Negative_regulation of WASF1 5 0.57 2.01 0.71 100.00
6 INT219774 Gene_expression of Wasf2 1 0.50 0.51 0 100.00
7 INT193376 Gene_expression of WASF1 7 0.75 1.6 0.2 100.00
8 INT107156 Regulation of WASF1 3 0.23 1.61 0.7 100.00
9 INT219760 Regulation of Wasf1 1 0.44 0.51 0 100.00
10 INT240411 Negative_regulation of Binding of Myo5a 1 0.09 0.97 0.21 100.00
11 INT48664 Negative_regulation of Gene_expression of GFAP 11 0.57 5.05 2.47 100.00
12 INT146316 Positive_regulation of RPS4X 1 0.67 0.86 0.09 100.00
13 INT176314 Binding of GCY 2 0.19 0.3 0.1 100.00
14 INT177581 Regulation of Fig4 113 0.41 39.26 27.75 100.00
15 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62 100.00
16 INT35584 Binding of ACLY 22 0.35 31.78 7.17 100.00
17 INT219772 Regulation of Wasf2 1 0.25 0.5 0 99.98
18 INT263804 Localization of MSLNL 3 0.55 2.13 0.14 99.98
19 INT335494 Binding of MSLNL 1 0.05 0.38 0.14 99.98
20 INT126812 Gene_expression of Cttn 9 0.57 0.81 1.23 99.92
21 INT265491 Gene_expression of CSPG4 16 0.58 7.27 1.07 99.90
22 INT119641 Gene_expression of EBAG9 25 0.76 33.2 3.96 99.84
23 INT197364 Gene_expression of MCAT 18 0.16 24.11 4.27 99.84
24 INT11052 Positive_regulation of Gene_expression of CD69 23 0.43 16.66 2.54 99.84
25 INT185219 Negative_regulation of Gene_expression of EBAG9 4 0.57 5.75 0.99 99.84
26 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 99.84
27 INT15802 Positive_regulation of Gene_expression of ISG20 16 0.42 8.16 4.03 99.84
28 INT305019 Positive_regulation of Gene_expression of NREP 3 0.44 5.1 0.32 99.84
29 INT319472 Phosphorylation of Abcd1 1 0.02 3.12 0.31 99.84
30 INT65500 Gene_expression of App 605 0.78 429.94 98.31 99.70
31 INT253403 Positive_regulation of Il6st 2 0.28 2.07 1.54 99.70
32 INT8629 Positive_regulation of COL7A1 72 0.69 40.66 12.09 99.68
33 INT114993 Binding of Myo5a 15 0.30 11.46 5.48 99.68
34 INT15419 Gene_expression of IL31RA 6 0.65 5.02 1.19 99.64
35 INT68695 Gene_expression of HTT 63 0.77 44.54 3.69 99.64
36 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 99.60
37 INT77795 Localization of Gdnf 26 0.81 6.29 8.55 99.60
38 INT14946 Binding of SPARCL1 5 0.31 6.57 1.29 99.58
39 INT305018 Gene_expression of NREP 8 0.68 23.31 0.72 99.56
40 INT305181 Negative_regulation of Gene_expression of NREP 1 0.36 2.96 0 99.56
41 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16 99.52
42 INT39758 Gene_expression of Fn1 57 0.65 34.38 6.02 99.52
43 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 99.50
44 INT8421 Regulation of Cntf 6 0.44 1.46 1.67 99.48
45 INT11048 Gene_expression of CD69 59 0.67 42.85 6.4 99.40
46 INT15804 Gene_expression of ISG20 83 0.75 44.33 10.58 99.40
47 INT20006 Gene_expression of MT1F 27 0.68 19.55 3.18 99.36
48 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16 99.36
49 INT4047 Binding of F13A1 105 0.43 66.54 11.81 99.36
50 INT224814 Regulation of EGOT 2 0.17 0.79 0.39 99.36
51 INT302036 Localization of Sema4c 1 0.68 0.24 0.08 99.36
52 INT22335 Regulation of Negative_regulation of ACE 10 0.44 7.01 1.77 99.32
53 INT197360 Regulation of MCAT 6 0.09 7.86 1.78 99.24
54 INT177832 Positive_regulation of Gene_expression of MT1F 5 0.28 2.75 1.05 99.24
55 INT128201 Negative_regulation of NCAM1 10 0.39 7.64 0.74 99.24
56 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16 99.20
57 INT208450 Negative_regulation of BCAN 1 0.03 0.43 0.12 99.16
58 INT24328 Gene_expression of Egf 97 0.75 59.65 9.42 99.12
59 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 99.12
60 INT31759 Negative_regulation of Gene_expression of Egf 6 0.53 5.33 0.77 99.12
61 INT69181 Positive_regulation of Col3a1 10 0.33 5.54 1.91 99.06
62 INT47712 Positive_regulation of App 135 0.69 101.38 28.94 99.04
63 INT45961 Gene_expression of Cspg4 22 0.78 7.21 3.43 99.00
64 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76 98.98
65 INT15003 Localization of GFAP 3 0.35 0.8 0.1 98.96
66 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 98.92
67 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 98.92
68 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 98.88
69 INT322218 Binding of SCGB1D4 2 0.05 1.88 0 98.88
70 INT119506 Negative_regulation of Egfr 32 0.55 23.75 3.67 98.80
71 INT110942 Transcription of TRPM8 16 0.69 13.69 1.31 98.80
72 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 98.60
73 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 98.60
74 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 98.56
75 INT181637 Gene_expression of CMA1 10 0.66 4.16 0.72 98.56
76 INT284714 Regulation of Gene_expression of CMA1 1 0.26 0.8 0 98.56
77 INT23955 Regulation of Vim 16 0.25 14.21 2.04 98.56
78 INT14442 Localization of GBE1 19 0.31 9.09 5.03 98.54
79 INT75939 Positive_regulation of SPARCL1 6 0.28 8.74 2.11 98.48
80 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91 98.48
81 INT25393 Positive_regulation of Localization of Ptger2 19 0.32 9.69 3.23 98.46
82 INT161749 Regulation of VUR 9 0.39 9.3 0.46 98.40
83 INT88545 Localization of MMRN1 21 0.78 16.67 4.01 98.40
84 INT115108 Negative_regulation of Gene_expression of FAS 9 0.57 9.16 1.23 98.32
85 INT1792 Positive_regulation of CGA 123 0.70 64.73 20.79 98.28
86 INT2982 Positive_regulation of Gene_expression of CGA 17 0.59 9.08 1.99 98.28
87 INT210399 Gene_expression of IGF2R 22 0.65 17.1 1.23 98.26
88 INT284709 Negative_regulation of CMA1 9 0.57 7.06 0.21 98.24
89 INT37865 Positive_regulation of Alad 5 0.27 3.13 0.6 98.24
90 INT134968 Localization of Ecm1 20 0.32 27.27 4.31 98.24
91 INT16214 Localization of F13A1 36 0.74 21.8 4.87 98.24
92 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 98.22
93 INT152937 Gene_expression of Olig2 2 0.53 2.82 0.72 98.20
94 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06 98.20
95 INT25396 Localization of Ptger2 83 0.78 46.81 14.81 98.14
96 INT17817 Binding of VUR 41 0.48 46.85 0.95 98.12
97 INT207891 Positive_regulation of Gene_expression of Lmrq1 5 0.28 3.87 0.05 98.12
98 INT207895 Positive_regulation of Gene_expression of Sgpp1 1 0.02 1.47 0 98.12
99 INT109650 Gene_expression of Aqp4 87 0.78 51.52 20.72 98.04
100 INT144683 Regulation of Rtn4r 3 0.26 0.88 0.36 98.00
101 INT23589 Positive_regulation of CALCR 9 0.67 6.73 1.25 98.00
102 INT138235 Positive_regulation of Pycard 2 0.33 1.66 0.62 98.00
103 INT326432 Regulation of Positive_regulation of Pycard 1 0.07 0.31 0.04 98.00
104 INT197359 Regulation of Gene_expression of MCAT 2 0.11 2.54 0.4 97.96
105 INT172961 Localization of Egf 26 0.71 16.74 1.81 97.96
106 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18 97.88
107 INT14778 Gene_expression of FCGR3A 25 0.75 16.25 3.86 97.88
108 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 97.88
109 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18 97.88
110 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 97.88
111 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 97.88
112 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 97.84
113 INT260525 Gene_expression of AMD1 25 0.66 24.58 1.32 97.84
114 INT174516 Regulation of Gene_expression of ISG20 6 0.27 4.2 0.85 97.76
115 INT185220 Regulation of EBAG9 2 0.27 2.74 0.56 97.72
116 INT229940 Positive_regulation of amd 10 0.49 27.97 0.15 97.68
117 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 97.68
118 INT305011 Positive_regulation of NREP 2 0.44 4.02 0.11 97.64
119 INT4535 Localization of PROC 106 0.73 76.24 21.1 97.60
120 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 97.60
121 INT286811 Negative_regulation of Regulation of Olig2 1 0.29 0.23 0.11 97.60
122 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.56
123 INT173693 Localization of Gopc 249 0.65 70.49 38.81 97.56
124 INT128061 Negative_regulation of Gene_expression of Serpine1 16 0.43 13.13 1.29 97.56
125 INT15941 Negative_regulation of Serpine1 42 0.58 21.07 4.95 97.56
126 INT64539 Gene_expression of Gpx3 14 0.58 9.42 3.64 97.48
127 INT64806 Binding of asa 10 0.30 4.11 3.14 97.48
128 INT219766 Gene_expression of Wasl 1 0.36 1.83 0 97.44
129 INT208125 Gene_expression of DDR1 10 0.06 8.15 1.03 97.40
130 INT230063 Gene_expression of Accs 1 0.48 2.61 0.4 97.40
131 INT133214 Regulation of PDX1 9 0.34 10.26 3.36 97.36
132 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45 97.32
133 INT110259 Negative_regulation of Vwf 6 0.42 3.3 1.1 97.32
134 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 97.28
135 INT4297 Negative_regulation of CFP 21 0.42 12.7 10.29 97.24
136 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61 97.20
137 INT118267 Negative_regulation of ARSD 14 0.36 8.27 1.44 97.20
138 INT236641 Regulation of Cks2 1 0.02 0.98 0.22 97.20
139 INT133744 Gene_expression of Vcan 27 0.74 10.64 2.85 97.16
140 INT197361 Negative_regulation of Gene_expression of MCAT 1 0.08 1.76 0.46 97.16
141 INT78194 Gene_expression of Acan 2 0.75 1.34 0.42 97.16
142 INT134325 Positive_regulation of IL4R 3 0.36 4.75 0.63 97.00
143 INT158059 Negative_regulation of ASD1 2 0.08 1.11 0.4 97.00
144 INT152710 Gene_expression of Dct 3 0.57 0.76 0.17 97.00
145 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 96.96
146 INT342571 Positive_regulation of Gene_expression of NUDT6 1 0.12 8.05 0.67 96.92
147 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 96.88
148 INT152936 Regulation of Olig2 2 0.42 1.11 0.23 96.88
149 INT185222 Regulation of Gene_expression of EBAG9 5 0.60 4.98 0.64 96.84
150 INT348090 Binding of PAX2 1 0.16 0.31 0.12 96.84
151 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 96.80
152 INT171058 Negative_regulation of PDX1 5 0.32 9.31 2.72 96.68
153 INT140191 Positive_regulation of Gene_expression of Mmp13 25 0.67 13.47 9.71 96.64
154 INT170294 Regulation of Gene_expression of Mmp13 5 0.44 4.25 1.26 96.64
155 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18 96.64
156 INT78190 Gene_expression of Tnc 10 0.75 21.23 2.91 96.64
157 INT259193 Positive_regulation of Fth1 2 0.14 1.75 0.09 96.56
158 INT212897 Negative_regulation of MAGED2 4 0.41 2.71 0 96.56
159 INT197363 Regulation of MT1F 1 0.08 1.14 0.21 96.52
160 INT80034 Positive_regulation of Gene_expression of FAS 32 0.67 30.34 8.51 96.52
161 INT348089 Positive_regulation of Binding of PAX2 1 0.21 0.16 0.06 96.52
162 INT97237 Transcription of TRPV1 33 0.72 10.56 12.4 96.48
163 INT153163 Regulation of TKCR 1 0.00 1.47 0.28 96.48
164 INT65261 Regulation of Col7a1 18 0.55 8.7 1.33 96.40
165 INT65390 Positive_regulation of Plat 30 0.70 23.31 9.31 96.36
166 INT155033 Gene_expression of Phlda2 18 0.30 9.45 0.5 96.36
167 INT171372 Positive_regulation of Gene_expression of Egf 16 0.66 9.82 0.84 96.24
168 INT145809 Gene_expression of stm 9 0.65 3.66 1.4 96.24
169 INT160533 Gene_expression of NUDT6 24 0.20 18.6 1.7 96.20
170 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 96.20
171 INT144680 Negative_regulation of Rtn4r 1 0.26 0.41 0.15 96.20
172 INT144681 Negative_regulation of Regulation of Rtn4r 1 0.19 0.41 0.15 96.20
173 INT144682 Negative_regulation of Regulation of Egfr 1 0.43 0.41 0.15 96.20
174 INT260527 Negative_regulation of AMD1 6 0.37 5 0.05 96.16
175 INT284713 Positive_regulation of Gene_expression of TGM2 1 0.04 0.73 0.03 96.12
176 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 96.04
177 INT5793 Binding of CTS 110 0.48 63.91 40.62 96.04
178 INT152060 Gene_expression of VUR 75 0.67 83.83 2.34 96.00
179 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 96.00
180 INT47528 Regulation of GFER 2 0.29 1.47 0.58 96.00
181 INT348092 Gene_expression of PAX2 1 0.29 0.32 0.16 96.00
182 INT348088 Positive_regulation of Gene_expression of PAX2 1 0.21 0.15 0.06 96.00
183 INT265480 Negative_regulation of CSPG4 5 0.32 2.37 0.31 95.84
184 INT208455 Protein_catabolism of Ntf3 1 0.23 0.75 0.06 95.72
185 INT208456 Positive_regulation of Protein_catabolism of Ntf3 1 0.16 0.75 0.06 95.72
186 INT262958 Localization of PAX2 2 0.32 0.83 0.15 95.68
187 INT348091 Positive_regulation of Localization of PAX2 1 0.21 0.15 0.06 95.68
188 INT24278 Gene_expression of FUT4 33 0.75 26.7 4.29 95.60
189 INT96842 Binding of Slc11a1 16 0.34 7.15 1.66 95.60
190 INT143487 Positive_regulation of Prp2l1 1 0.21 0.45 0.09 95.58
191 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 95.56
192 INT259692 Gene_expression of TNFAIP8L2 3 0.06 3.94 1.13 95.56
193 INT67980 Positive_regulation of Positive_regulation of CCL2 7 0.49 5.89 1.85 95.56
194 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 95.44
195 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 95.44
196 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 95.44
197 INT115501 Gene_expression of TGM2 8 0.64 4.56 0.28 95.40
198 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 95.36
199 INT58484 Regulation of Il4 12 0.45 8.67 6.09 95.32
200 INT154527 Gene_expression of POU5F1 180 0.78 34.01 4.34 95.24
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