D:Ciguatera Poisoning

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pChart

Disease Term
Synonyms CIGUATERA, Ciguatera Poisonings, Poisoning Ciguatera, Poisonings Ciguatera
Documents 52
Hot Single Events 16
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Ciguatera Poisoning. They are ordered first by their relevance to Ciguatera Poisoning and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT331768 Binding of Arg1 and NOSTRIN 1 0.01 0.6 0.17 52.92
2 INT331766 Binding of Arg1 and Nos2 1 0.17 0.6 0.17 52.92
3 INT320659 Vsig2 Positive_regulation of Transcription of Nos2 1 0.07 0.65 0.07 50.00
4 INT331767 Hand1 Positive_regulation of Nos2 1 0.08 0.48 0.23 43.12
5 INT243557 Binding of PSPH and SPECC1 1 0.01 1.19 0.12 5.00
6 INT261883 PKD2 Positive_regulation of Localization of Ca2 1 0.02 0.67 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Ciguatera Poisoning. They are ordered first by their pain relevance and then by number of times they were reported in Ciguatera Poisoning. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT145594 Gene_expression of Mtx1 64 0.57 35.33 30.35 99.92
2 INT165871 Negative_regulation of Gene_expression of Vsig2 2 0.24 0.83 0.32 98.92
3 INT92632 Gene_expression of Vsig2 48 0.50 19.93 3.04 98.36
4 INT34370 Positive_regulation of Cfp 26 0.46 15.21 6.12 97.94
5 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 97.68
6 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56 97.12
7 INT301479 Positive_regulation of Gene_expression of Vsig2 2 0.32 2.78 0.08 96.96
8 INT34372 Gene_expression of Cfp 102 0.67 37.66 8.72 96.96
9 INT45179 Gene_expression of sea 8 0.58 3.4 2.99 96.92
10 INT32072 Positive_regulation of sea 7 0.40 0.91 1.44 96.48
11 INT95929 Binding of Cfp 6 0.27 7.12 0.74 95.80
12 INT7147 Localization of Vsig2 7 0.49 4.42 0.86 95.44
13 INT14091 Binding of Vsig2 8 0.42 3.21 3.91 94.88
14 INT331760 Regulation of Ripk4 1 0.01 0.28 0.08 94.80
15 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89 88.56
16 INT152616 Gene_expression of SPECC1 8 0.66 8.43 4.32 81.28
17 INT160440 Positive_regulation of Crem 48 0.69 20.38 7.66 77.96
18 INT107604 Binding of NALCN 4 0.07 3.08 0.65 77.84
19 INT205005 Transcription of SPECC1 3 0.59 1.28 0.14 75.32
20 INT243550 Gene_expression of PSPH 7 0.25 7.49 0.4 75.24
21 INT153371 Binding of Cfp 27 0.47 7.33 7.48 75.00
22 INT210975 Regulation of Cfp 10 0.24 5.3 3.93 73.88
23 INT3545 Positive_regulation of Mtx1 27 0.42 11.97 14.83 71.84
24 INT65391 Positive_regulation of Vsig2 13 0.32 5.71 1.49 67.52
25 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 62.96
26 INT94055 Gene_expression of Arg1 22 0.68 20.81 6.13 58.56
27 INT94054 Regulation of Arg1 5 0.47 5.37 1.57 58.56
28 INT331764 Regulation of Gene_expression of Arg1 7 0.36 4.65 1.1 58.56
29 INT53491 Negative_regulation of Jun 28 0.57 14.2 6.9 56.80
30 INT70816 Negative_regulation of Fos 32 0.58 13 11.18 56.80
31 INT74262 Negative_regulation of Egr1 15 0.57 7.51 2.41 56.80
32 INT115046 Gene_expression of Crem 68 0.77 27.24 10.01 55.56
33 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 52.16
34 INT73959 Positive_regulation of NOSTRIN 49 0.61 31.1 11.27 52.16
35 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 50.00
36 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 50.00
37 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 50.00
38 INT66281 Transcription of Nos2 81 0.71 39.49 20.37 50.00
39 INT4297 Negative_regulation of CFP 21 0.42 12.7 10.29 50.00
40 INT19132 Gene_expression of CYP27A1 83 0.75 34.31 10.17 50.00
41 INT7437 Gene_expression of CFP 21 0.65 4.93 3.89 50.00
42 INT134694 Binding of CYP27A1 10 0.47 5.61 3.56 50.00
43 INT27660 Binding of CFP 21 0.40 12.47 3.51 50.00
44 INT112081 Negative_regulation of Vsig2 9 0.34 2.37 1.69 50.00
45 INT168558 Positive_regulation of Gene_expression of Cfp 10 0.43 4.54 1.59 50.00
46 INT129231 Gene_expression of Ddx41 29 0.63 9.73 1.52 50.00
47 INT218779 Negative_regulation of Cfp 7 0.14 2.89 1.2 50.00
48 INT112082 Regulation of Vsig2 13 0.40 1.89 0.98 50.00
49 INT91474 Positive_regulation of GRIN2A 4 0.67 1.83 0.95 50.00
50 INT68788 Localization of CFP 7 0.63 1.07 0.93 50.00
51 INT128750 Binding of Ddx41 13 0.34 4.35 0.57 50.00
52 INT26073 Gene_expression of Scd1 17 0.70 9.17 0.47 50.00
53 INT16808 Binding of Scd1 5 0.00 7.18 0.33 50.00
54 INT65386 Positive_regulation of Localization of Vsig2 2 0.32 0.16 0.23 50.00
55 INT320654 Negative_regulation of Localization of Vsig2 1 0.24 0.75 0.17 50.00
56 INT320656 Transcription of Vsig2 1 0.45 0.45 0.07 50.00
57 INT320657 Positive_regulation of Regulation of Vsig2 1 0.28 0.39 0 50.00
58 INT245105 Binding of Axin1 2 0.06 0.65 0 50.00
59 INT94056 Positive_regulation of Gene_expression of Arg1 8 0.60 6.57 1.95 47.12
60 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 46.20
61 INT331758 Regulation of Gene_expression of Vsig2 1 0.20 1.49 0.71 34.72
62 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 33.04
63 INT158843 Regulation of NALCN 6 0.04 2.89 3.63 11.04
64 INT25607 Binding of Il1 82 0.47 64.4 23.9 8.20
65 INT65459 Binding of Racgap1 9 0.07 4.57 2.28 8.20
66 INT19775 Localization of Il1 183 0.78 145.5 50.91 7.84
67 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 7.84
68 INT199077 Localization of Racgap1 7 0.73 2.43 0.42 7.84
69 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 7.00
70 INT12725 Positive_regulation of Racgap1 66 0.68 32.74 19.29 7.00
71 INT170755 Positive_regulation of Positive_regulation of IFN1@ 17 0.67 8.72 3.65 7.00
72 INT54515 Positive_regulation of Positive_regulation of Racgap1 6 0.12 2.33 2.34 7.00
73 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 6.60
74 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 5.00
75 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 5.00
76 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 5.00
77 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05 5.00
78 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31 5.00
79 INT4822 Localization of Ca2 417 0.80 99.57 96.45 5.00
80 INT123584 Gene_expression of Trpa1 176 0.78 83 78.65 5.00
81 INT12476 Negative_regulation of TRPV1 124 0.59 47.95 77.98 5.00
82 INT117601 Positive_regulation of Trpa1 174 0.70 72.41 71.9 5.00
83 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01 5.00
84 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 5.00
85 INT49436 Binding of TRPV1 145 0.48 38.35 55.08 5.00
86 INT95789 Positive_regulation of Grm5 42 0.55 20.1 33.72 5.00
87 INT5489 Localization of CA2 172 0.80 39.46 33.56 5.00
88 INT109820 Gene_expression of Trpv4 121 0.78 39.69 33.11 5.00
89 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 5.00
90 INT117632 Gene_expression of Trpm8 99 0.78 29.41 30.9 5.00
91 INT149387 Negative_regulation of Trpa1 55 0.59 21.91 28.31 5.00
92 INT20129 Regulation of Il1 53 0.53 44.14 19.89 5.00
93 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 5.00
94 INT111416 Positive_regulation of Trpm8 65 0.70 14.62 17.13 5.00
95 INT5536 Regulation of NA 74 0.59 16.61 15.36 5.00
96 INT113625 Positive_regulation of Gene_expression of Ca2 47 0.50 9.82 14.07 5.00
97 INT103547 Gene_expression of TRPV3 47 0.78 17.06 13.34 5.00
98 INT11793 Negative_regulation of CA2 78 0.57 19.63 12.35 5.00
99 INT23535 Positive_regulation of Localization of CA2 41 0.41 13.52 9.43 5.00
100 INT119098 Positive_regulation of TRPV3 20 0.68 10.12 9.01 5.00
101 INT146241 Positive_regulation of Gene_expression of Trpa1 23 0.69 8.07 8.74 5.00
102 INT4021 Positive_regulation of PLA2G1B 35 0.70 23.27 8.2 5.00
103 INT134106 Positive_regulation of SPECC1 14 0.68 9.44 8.09 5.00
104 INT36960 Gene_expression of vs 33 0.43 20.77 6.97 5.00
105 INT139580 Negative_regulation of Trpm8 19 0.58 3.8 6.26 5.00
106 INT245574 Regulation of SPECC1 5 0.44 6.03 5 5.00
107 INT181362 Negative_regulation of Ccl5 21 0.40 15.63 4.96 5.00
108 INT134378 Binding of Trpm8 8 0.48 1.74 2.95 5.00
109 INT137967 Positive_regulation of Gene_expression of Trpm8 11 0.70 3.29 2.66 5.00
110 INT12485 Binding of DNAH8 17 0.48 4.24 2.54 5.00
111 INT11787 Positive_regulation of Positive_regulation of NA 14 0.21 2.97 2.46 5.00
112 INT147543 Positive_regulation of Positive_regulation of Trpa1 7 0.69 2.24 2.38 5.00
113 INT123843 Gene_expression of soc 14 0.58 5.22 1.96 5.00
114 INT175084 Gene_expression of Mup1 11 0.61 3.58 1.81 5.00
115 INT86247 Gene_expression of Bcl2l10 14 0.34 12.21 1.61 5.00
116 INT81726 Binding of soc 42 0.42 9.92 1.61 5.00
117 INT18158 Negative_regulation of Positive_regulation of NA 11 0.36 1.45 1.45 5.00
118 INT331761 Negative_regulation of C5ar1 3 0.08 2.65 1.25 5.00
119 INT114568 Negative_regulation of Trpc1 4 0.41 0.56 1.19 5.00
120 INT331759 Negative_regulation of Negative_regulation of C5ar1 1 0.01 1.81 1.18 5.00
121 INT70323 Negative_regulation of Gene_expression of CA2 13 0.41 6.55 0.97 5.00
122 INT261882 Positive_regulation of Protein_catabolism of WAS 1 0.03 0.14 0.92 5.00
123 INT261876 Protein_catabolism of WAS 1 0.05 0.14 0.92 5.00
124 INT129174 Gene_expression of PKD1 24 0.67 14.91 0.74 5.00
125 INT137850 Gene_expression of PKD2 9 0.65 6.68 0.63 5.00
126 INT193112 Negative_regulation of Gene_expression of Bcl2l10 5 0.02 3.03 0.45 5.00
127 INT261870 Gene_expression of Pkd2l1 10 0.54 1.5 0.42 5.00
128 INT167786 Gene_expression of Trpm1 2 0.12 0.81 0.38 5.00
129 INT146936 Gene_expression of Trpm6 2 0.28 0.22 0.25 5.00
130 INT113251 Negative_regulation of soc 5 0.50 4.11 0.24 5.00
131 INT338108 Regulation of Gene_expression of PSPH 1 0.16 1.2 0.17 5.00
132 INT261874 Binding of Trpm3 1 0.19 0 0.15 5.00
133 INT196122 Gene_expression of Trpm4 2 0.52 0.52 0.11 5.00
134 INT221994 Positive_regulation of Gene_expression of Bcl2l10 2 0.07 1.12 0.1 5.00
135 INT227075 Negative_regulation of Gene_expression of soc 2 0.29 0.57 0.09 5.00
136 INT261875 Gene_expression of Trpm3 1 0.34 0 0.09 5.00
137 INT261869 Regulation of Positive_regulation of Trpa1 1 0.35 0 0.06 5.00
138 INT261879 Binding of PKD2 3 0.13 2.59 0.05 5.00
139 INT211006 Binding of PKD1 6 0.22 2.69 0.05 5.00
140 INT251815 Negative_regulation of SPECC1 1 0.37 1.95 0.04 5.00
141 INT331765 Protein_catabolism of Ppig 1 0.13 0.06 0.03 5.00
142 INT261873 Regulation of Trpm3 1 0.23 0.28 0.03 5.00
143 INT261880 Negative_regulation of Binding of PKD1 1 0.16 0.6 0 5.00
144 INT261878 Negative_regulation of Binding of PKD2 1 0.14 0.6 0 5.00
145 INT243546 Regulation of PSPH 2 0.20 0.89 0 5.00
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