D:Circadian Rhythm Sleep Disorders

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Disease Term
Synonyms Advanced Sleep Phase Syndrome, Cycle Disorder Sleep Wake, Cycle Disorders Sleep Wake, DELAYED SLEEP PHASE SYNDROME, DISTURBED NYCTOHEMERAL RHYTHM, Disturbed Nyctohemeral Rhythms, Non 24 Hour Sleep Wake Disorder, Nonorganic Sleep Wake Cycle Disorders, Nyctohemeral Rhythm Disturbed, Nyctohemeral Rhythms Disturbed, SHIFT WORK SLEEP DISORDER
Documents 13
Hot Single Events 0
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Circadian Rhythm Sleep Disorders. They are ordered first by their relevance to Circadian Rhythm Sleep Disorders and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT274353 DST Regulation of Gopc 1 0.00 0 0.17 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Circadian Rhythm Sleep Disorders. They are ordered first by their pain relevance and then by number of times they were reported in Circadian Rhythm Sleep Disorders. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT142735 Regulation of RLS 33 0.53 45.83 11.35 76.72
2 INT234289 Binding of Swd1 1 0.03 5.79 0.23 67.92
3 INT27492 Gene_expression of Swd1 4 0.50 2.07 0.68 29.56
4 INT28325 Negative_regulation of Tst 13 0.51 12.41 3.16 10.88
5 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 5.00
6 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 5.00
7 INT920 Localization of PLOD1 223 0.81 42.25 78.7 5.00
8 INT33567 Gene_expression of CALM1 139 0.67 48.85 56.14 5.00
9 INT913 Regulation of Localization of PLOD1 71 0.62 8.64 32.72 5.00
10 INT7975 Regulation of PLOD1 97 0.62 20.9 30.51 5.00
11 INT32165 Binding of CALM1 92 0.48 24.19 29.57 5.00
12 INT20003 Gene_expression of Scn2a1 125 0.71 8.78 23.94 5.00
13 INT68347 Negative_regulation of Cyp2d4 34 0.58 7.62 18.35 5.00
14 INT32515 Negative_regulation of B4GALNT1 82 0.43 28.1 17.46 5.00
15 INT50404 Negative_regulation of CYP1A2 49 0.59 8.61 17.35 5.00
16 INT47742 Binding of Flvcr2 26 0.42 3.28 15.87 5.00
17 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 5.00
18 INT67101 Gene_expression of DST 47 0.54 25.92 9.59 5.00
19 INT1682 Negative_regulation of Rem1 28 0.37 7.38 8.4 5.00
20 INT106056 Gene_expression of Hcrt 77 0.76 35.35 8.16 5.00
21 INT7813 Regulation of SRI 25 0.61 6.18 8.13 5.00
22 INT17867 Positive_regulation of Cyp1a2 39 0.69 2.58 7.57 5.00
23 INT162253 Gene_expression of BAG3 30 0.59 20.16 7.18 5.00
24 INT17674 Localization of Scn2a1 32 0.61 1.73 6.79 5.00
25 INT175482 Positive_regulation of Gene_expression of CALM1 12 0.44 3.47 6.54 5.00
26 INT2039 Regulation of CYP2B6 30 0.60 7.75 6.43 5.00
27 INT91217 Positive_regulation of BAG3 22 0.48 16.57 6.06 5.00
28 INT28015 Regulation of Cyp3a23/3a1 19 0.40 6.32 5.79 5.00
29 INT55419 Regulation of CYP1A2 19 0.62 5.3 4.75 5.00
30 INT162254 Regulation of BAG3 28 0.41 18.12 4.75 5.00
31 INT126685 Gene_expression of Rem1 30 0.65 11.21 3.61 5.00
32 INT106057 Negative_regulation of Hcrt 27 0.57 15.5 3.47 5.00
33 INT28166 Positive_regulation of Rem1 8 0.40 7.96 3.19 5.00
34 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53 5.00
35 INT15606 Localization of FSHB 24 0.78 9.16 2.49 5.00
36 INT15604 Gene_expression of FSHB 30 0.56 9.7 2.45 5.00
37 INT80733 Binding of Scn2a1 11 0.30 1.09 2.3 5.00
38 INT106055 Negative_regulation of Gene_expression of Hcrt 15 0.46 5.64 2.09 5.00
39 INT70526 Binding of CALR 11 0.35 7.09 1.97 5.00
40 INT62127 Localization of SRI 12 0.45 10.21 1.54 5.00
41 INT7812 Negative_regulation of SRI 10 0.59 4.28 1.46 5.00
42 INT16153 Gene_expression of Cenpj 7 0.77 2.56 1.42 5.00
43 INT83822 Protein_catabolism of CYP2C9 3 0.46 1.16 1.31 5.00
44 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25 5.00
45 INT124940 Binding of MTNR1A 8 0.36 2.29 0.9 5.00
46 INT238515 Localization of BAG3 3 0.34 0.4 0.8 5.00
47 INT157282 Localization of CYP1A2 5 0.75 0.54 0.76 5.00
48 INT274343 Localization of Mt1 1 0.11 0.84 0.48 5.00
49 INT274341 Positive_regulation of Gene_expression of Epha1 1 0.01 0 0.46 5.00
50 INT274342 Gene_expression of Epha1 1 0.01 0 0.46 5.00
51 INT94543 Binding of MT2A 5 0.29 0.96 0.36 5.00
52 INT84396 Positive_regulation of Positive_regulation of Cyp1a2 2 0.24 0.22 0.34 5.00
53 INT120210 Negative_regulation of Hcrtr1 3 0.58 1.17 0.34 5.00
54 INT258092 Regulation of Gene_expression of Hcrt 2 0.44 2.6 0.29 5.00
55 INT125419 Positive_regulation of Cyp4a3 5 0.18 2.05 0.27 5.00
56 INT195871 Positive_regulation of Gene_expression of CALR 9 0.29 3 0.27 5.00
57 INT238516 Regulation of Regulation of CYP2B6 1 0.05 0.73 0.27 5.00
58 INT78047 Negative_regulation of GLB1 2 0.51 1.3 0.25 5.00
59 INT64834 Negative_regulation of Cenpj 3 0.42 0.58 0.19 5.00
60 INT97578 Regulation of FSHB 3 0.26 1.41 0.17 5.00
61 INT137622 Protein_catabolism of CYP2D6 2 0.38 0 0.17 5.00
62 INT75014 Regulation of Cyp2a1 3 0.06 1.22 0.09 5.00
63 INT238518 Gene_expression of SERTAD1 1 0.18 0.74 0.07 5.00
64 INT274054 Localization of CYP1A1 1 0.12 0 0.07 5.00
65 INT274055 Protein_catabolism of CYP1A2 1 0.47 0 0.06 5.00
66 INT274056 Protein_catabolism of CYP1A1 1 0.15 0 0.06 5.00
67 INT284126 Positive_regulation of Cyp2b3 1 0.37 0 0.06 5.00
68 INT274053 Gene_expression of FBXL15 2 0.65 1.56 0.03 5.00
69 INT238517 Regulation of SERTAD1 1 0.12 0 0 5.00
70 INT284125 Regulation of Cenpj 1 0.07 0.6 0 5.00
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