D:Cirrhosis

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Disease Term
Synonyms Biliary Cirrhosis, Cardiac Cirrhosis, Cirrhoses Hepatic, Cirrhoses Liver, CIRRHOSIS HEPATIC, Cirrhosis Liver, Cirrhotic, Fibrogenesis Of The Liver, Fibroses Liver, FIBROSIS LIVER, FIBROTIC LIVER
Documents 2282
Hot Single Events 200
Hot Interactions 111

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cirrhosis. They are ordered first by their relevance to Cirrhosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT218706 Olr811 Positive_regulation of MMP1 1 0.00 3.16 0.45 100.00
2 INT87808 Binding of Gpt and HCC 3 0.04 5.09 0.07 100.00
3 INT210365 Binding of FUT1 and GPM6A 1 0.00 1.1 0.08 100.00
4 INT312346 FUT1 Positive_regulation of Gene_expression of COL11A1 1 0.17 1.02 0.03 100.00
5 INT210364 Binding of FUT1 and GOPC 1 0.01 0.53 0.08 100.00
6 INT174917 Negative_regulation of PLG Negative_regulation of Positive_regulation of FUT1 1 0.01 0.68 0.13 100.00
7 INT200640 Agtr2 Positive_regulation of Gene_expression of TGFB1 1 0.03 1.35 0.29 100.00
8 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29 100.00
9 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29 100.00
10 INT312769 Binding of Apoe and Pon1 1 0.04 0.86 0 100.00
11 INT212440 STAT3 Regulation of Phosphorylation of SOAT1 1 0.11 1.42 0.05 99.96
12 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77 99.92
13 INT348593 ZACN Regulation of Positive_regulation of PPARG 1 0.14 0.41 0 99.72
14 INT218664 Olr811 Regulation of Timp1 1 0.00 0.9 0.22 99.54
15 INT218673 Olr811 Regulation of Mmp1a 1 0.00 0.7 0.13 99.54
16 INT222974 NFKBIB Negative_regulation of NFKB2 Negative_regulation of ICAM1 1 0.00 1.6 0.33 99.40
17 INT180345 Binding of HLA-DMA and HLA-DRB4 1 0.00 1.51 0.12 99.34
18 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 99.28
19 INT343825 IRF6 Regulation of Gene_expression of FUT1 1 0.00 1.74 0.5 99.20
20 INT218669 Olr811 Negative_regulation of Phosphorylation of Smad2 1 0.01 0.18 0 99.20
21 INT343569 Negative_regulation of Synm Positive_regulation of Gpt 1 0.01 0.96 0.29 99.04
22 INT343571 Synm Positive_regulation of ALPP 1 0.01 1.28 0.28 99.04
23 INT343570 Synm Positive_regulation of Gpt 1 0.01 1.28 0.28 99.04
24 INT343573 Synm Positive_regulation of SLC17A5 1 0.17 1.28 0.28 99.04
25 INT222973 NFKBIB Negative_regulation of NFKB2 Negative_regulation of IL6 1 0.00 1.6 0.33 98.96
26 INT355866 Binding of EXT1 and Afp 1 0.04 3.56 0 98.84
27 INT218662 Olr811 Positive_regulation of Positive_regulation of Mapk14 1 0.00 0.54 0.08 98.84
28 INT355867 Binding of Afp and HCC 1 0.01 2.25 0.14 98.84
29 INT210362 Binding of GPM6A and IGF2R 1 0.00 0.57 0 98.76
30 INT249090 FOXL1 Regulation of Regulation of ICAM1 1 0.12 1.03 0.37 98.68
31 INT348594 MECP2 Regulation of Gene_expression of PPARG 1 0.34 0.43 0 98.56
32 INT348584 EZH2 Regulation of Gene_expression of PPARG 1 0.30 0.43 0 98.56
33 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66 98.32
34 INT346455 IFNA1 Regulation of HCC 1 0.02 1.64 0.23 98.32
35 INT312345 Binding of COL2A1 and COL5A2 1 0.00 1.21 0 98.20
36 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 98.08
37 INT343846 MAPK1 Positive_regulation of FOS 1 0.04 1.29 0.44 98.08
38 INT326017 Binding of PCNA and HCC 1 0.00 0.99 0 97.86
39 INT222976 NFKBIB Negative_regulation of NFKB2 1 0.01 1.58 0.32 97.68
40 INT224922 Binding of FAP and TARM1 1 0.06 1.4 0.06 97.40
41 INT121631 PDGFD Positive_regulation of TGM1 1 0.01 0.68 0.18 97.32
42 INT210363 Binding of ALB and M6PR 1 0.00 1.19 0.1 96.72
43 INT252821 Binding of CD4 and IL12A 1 0.02 1.36 0.19 96.32
44 INT218707 Mmp1a Negative_regulation of MMP1 1 0.00 2.03 0.38 96.28
45 INT218709 Mmp1a Negative_regulation of TIMP1 1 0.00 1.84 0.28 96.28
46 INT218660 Mmp1a Negative_regulation of Timp1 1 0.02 1.84 0.28 96.28
47 INT303446 Timp1 Negative_regulation of Mmp2 1 0.19 0.33 0.31 95.84
48 INT252817 Binding of CD8A and IL12A 1 0.02 1.36 0.19 95.60
49 INT251701 Bche Regulation of Gene_expression of Acot1 1 0.03 0.25 0.03 94.84
50 INT121633 PTGER1 Positive_regulation of PDGFD 1 0.01 0.67 0.19 94.44
51 INT121632 PTGER1 Positive_regulation of TGM1 1 0.00 0.67 0.19 94.44
52 INT252826 ROS1 Regulation of Gene_expression of CCL2 1 0.20 2.17 0.62 94.20
53 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62 93.88
54 INT218713 Mmp1a Negative_regulation of Gene_expression of TIMP1 1 0.00 0.18 0.1 93.76
55 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89 93.76
56 INT188427 IL6 Positive_regulation of Pdxp 1 0.00 0.84 0.38 93.60
57 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72 93.48
58 INT161946 Alk Negative_regulation of Localization of Ngf 1 0.10 1.01 0.72 93.48
59 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25 92.96
60 INT17726 Positive_regulation of Binding of AKR1A1 and Aldh2 1 0.11 0.35 0.41 92.64
61 INT17725 Binding of AKR1A1 and Aldh2 1 0.08 0.35 0.4 92.64
62 INT280007 Binding of CLTC and PAEP 1 0.06 0.8 0.08 92.44
63 INT252788 Binding of IL12A and IL18 1 0.01 1.33 0.19 92.16
64 INT106630 Binding of GRK5 and PRKCA 1 0.16 0.82 0.19 91.72
65 INT181995 TIMP1 Negative_regulation of Mmp9 1 0.01 1.38 0.4 91.60
66 INT355864 EXT1 Positive_regulation of Positive_regulation of Afp 1 0.05 0.93 0 91.40
67 INT312794 Hdl1 Regulation of Pon1 1 0.02 1.63 0.15 91.36
68 INT329847 PPARA Regulation of Gene_expression of CREB3L3 1 0.17 0.84 0.13 91.28
69 INT218671 Mmp1a Negative_regulation of Gene_expression of Timp1 1 0.02 0.6 0.06 91.04
70 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76 90.92
71 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76 90.92
72 INT161952 TGFB2 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.08 0.99 0.76 90.92
73 INT225104 CNR1 Positive_regulation of Gene_expression of RETNLB 1 0.01 1.41 1.14 90.08
74 INT218659 Olr811 Regulation of Positive_regulation of Mmp1a 1 0.00 0.17 0.1 89.36
75 INT178723 Binding of ALB and TNNI3 1 0.17 0.91 0 89.24
76 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54 89.16
77 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74 88.68
78 INT355865 EXT1 Positive_regulation of Cm3 1 0.04 0.99 0 88.40
79 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 88.24
80 INT19535 Binding of ADRA1D and ALB 3 0.42 0.8 1.15 87.72
81 INT339676 CSF2 Positive_regulation of HGF 1 0.08 0.46 0 87.68
82 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32 86.04
83 INT303445 Mmp3 Positive_regulation of Mmp9 1 0.01 1.19 0.47 85.52
84 INT252814 ELANE Positive_regulation of Positive_regulation of CCL2 1 0.05 0.8 0.2 85.00
85 INT252782 ROS1 Positive_regulation of Positive_regulation of CCL2 1 0.22 0.8 0.2 85.00
86 INT348583 MECP2 Regulation of PPARG 1 0.46 0.73 0 84.84
87 INT348591 EZH2 Regulation of Negative_regulation of MECP2 1 0.15 0.73 0 84.84
88 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25 84.72
89 INT348585 EZH2 Regulation of PPARG 1 0.41 0.73 0 84.44
90 INT331576 IFN1@ Positive_regulation of TNFSF10 1 0.00 0.27 0.08 84.08
91 INT331575 Negative_regulation of IFN1@ Positive_regulation of TNFSF10 1 0.00 0.27 0.08 84.08
92 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21 83.60
93 INT296893 Nps Negative_regulation of Gene_expression of REN 1 0.00 1.05 0.04 83.40
94 INT218663 Olr811 Positive_regulation of Gene_expression of Smad7 1 0.01 0.45 0 83.20
95 INT252767 CAT Regulation of Gpx1 1 0.00 0.25 0.04 83.08
96 INT37489 Binding of ADRA1D and Alb 1 0.34 0.84 0.11 83.04
97 INT232902 Binding of YWHAQ and Krt18 1 0.34 0.96 0.07 82.52
98 INT232901 Regulation of Binding of YWHAQ and Krt18 1 0.41 0.96 0.07 82.52
99 INT333051 Binding of HIVEP1 and NOLC1 1 0.00 4.11 0.07 82.24
100 INT206855 Binding of ESR1 and PPARA 1 0.03 1.21 0.07 82.24
101 INT252810 ROS1 Regulation of Gene_expression of MMRN1 1 0.04 0.16 0 82.20
102 INT103769 AMY2A Positive_regulation of IFNA2 1 0.01 0.26 0 82.08
103 INT294742 Lep Positive_regulation of Localization of Icam1 1 0.15 0.48 0.11 81.88
104 INT252798 ELANE Regulation of Gene_expression of ROS1 1 0.04 0.16 0 81.68
105 INT252775 ELANE Regulation of Gene_expression of MMRN1 1 0.01 0.16 0 81.68
106 INT127966 GPT Positive_regulation of SLC17A5 1 0.50 1.81 0.14 81.40
107 INT251705 Fig4 Regulation of Localization of Chat 1 0.05 0.23 0.08 80.92
108 INT251703 Fig4 Regulation of Localization of Ache 1 0.07 0.23 0.08 80.92
109 INT218668 Binding of Ppia and Olr811 1 0.00 0.98 0.05 80.88
110 INT251712 Fig4 Regulation of Ache 1 0.02 0.23 0.08 80.20
111 INT343865 IRF6 Positive_regulation of TIRAP 1 0.03 0.28 0.08 80.16
112 INT251710 Fig4 Regulation of Chat 1 0.03 0.23 0.08 79.84
113 INT280008 Binding of IFNA1 and PAEP 2 0.08 1.29 0.25 79.40
114 INT218712 Timp1 Regulation of MMP1 1 0.00 0.41 0.03 79.36
115 INT218708 Mmp1a Regulation of MMP1 1 0.00 0.41 0.03 79.36
116 INT312792 Binding of Pon1 and Hdl1 1 0.04 1.85 0.11 78.48
117 INT311950 FBN1 Positive_regulation of Gene_expression of PGF 1 0.00 0.15 0.26 78.48
118 INT218710 MMP1 Regulation of Positive_regulation of Col1a1 1 0.00 0.15 0.07 78.28
119 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34 78.00
120 INT343841 ZBP1 Regulation of Transcription of IFN1@ 1 0.00 0.2 0.19 77.52
121 INT333394 CFD Negative_regulation of Gene_expression of Cat 1 0.03 0.79 0.22 77.52
122 INT333397 CFD Negative_regulation of Gene_expression of Nos2 1 0.04 0.8 0.22 77.52
123 INT280004 Binding of IFNA1 and CDIPT 1 0.01 0.74 0.08 76.24
124 INT280005 Binding of PAEP and CDIPT 1 0.01 0.74 0.08 75.92
125 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 75.68
126 INT343854 TIRAP Positive_regulation of IRF3 1 0.06 0.19 0.19 74.52
127 INT190684 Binding of A2M and IGF1 1 0.16 1.54 0.1 74.36
128 INT224921 Binding of TTR and TARM1 1 0.06 1.06 0 74.36
129 INT343837 TICAM1 Positive_regulation of IRF3 1 0.03 0.19 0.19 73.80
130 INT343831 TICAM1 Positive_regulation of Gene_expression of TLR4 1 0.11 0.19 0.19 73.80
131 INT350363 Gatm Negative_regulation of NOS1 1 0.00 0.31 0.17 72.56
132 INT332700 Binding of F12 and KNG1 1 0.15 1.05 0.21 71.72
133 INT348587 Binding of MECP2 and PPARG 1 0.32 0.25 0 71.16
134 INT279799 ATP6V0A2 Regulation of ERBB3 1 0.00 1.77 0.12 69.08
135 INT279804 ATP6V0A2 Regulation of MCF2 1 0.00 1.76 0.12 69.08
136 INT178910 Ins1 Negative_regulation of Gene_expression of Pck1 1 0.04 0.34 0.31 69.04
137 INT241778 AVP Positive_regulation of AVPR1A 1 0.10 1.32 0 68.96
138 INT301667 Tlr4 Positive_regulation of Gene_expression of CYBB 1 0.01 0.84 0.03 68.28
139 INT301662 Binding of Tlr4 and Positive_regulation of Gene_expression of CYBB 1 0.01 0.84 0.03 68.28
140 INT266423 Binding of HMGB1 and Mapk3 1 0.04 0.9 0.2 68.24
141 INT266410 Binding of HMGB1 and Mapk14 1 0.03 0.91 0.2 68.24
142 INT266416 Binding of HMGB1 and Mapk1 1 0.06 0.9 0.2 68.24
143 INT266414 Binding of HMGB1 and Mapk8 1 0.03 0.91 0.2 68.24
144 INT318919 Binding of ATP7B and COMMD1 1 0.37 0.76 0 67.16
145 INT343863 Binding of IRF1 and IRF3 1 0.03 0.12 0.17 67.00
146 INT346459 Binding of RNASE1 and ROS1 1 0.06 1.42 0.18 66.72
147 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24 66.56
148 INT320267 CCNA2 Positive_regulation of CDK1 1 0.12 1.08 0.08 66.36
149 INT278243 HGF Positive_regulation of Gene_expression of Hsdr1 1 0.00 0.4 0.06 65.92
150 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68 65.48
151 INT260739 Mapk14 Regulation of Positive_regulation of Sp1 1 0.01 1.06 0.25 65.48
152 INT260743 Mapk14 Regulation of Gene_expression of Il10 1 0.04 0.99 0.24 65.48
153 INT343829 TLR1 Positive_regulation of TBCE 1 0.03 0.96 0.85 65.44
154 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73 65.36
155 INT348033 Fndc3b Positive_regulation of Vps54 1 0.00 1.87 0.03 63.40
156 INT343848 Positive_regulation of TLR4 Positive_regulation of STAT1 1 0.17 0.16 0.15 60.84
157 INT343835 TLR4 Positive_regulation of STAT1 1 0.17 0.11 0.15 60.84
158 INT346453 Binding of DDX58 and IFIH1 1 0.00 1.04 0.03 60.60
159 INT247114 Binding of HLA-A and MPZ 1 0.00 6.26 0 60.24
160 INT218675 Olr811 Negative_regulation of Gene_expression of Timp1 1 0.00 0.22 0.22 60.04
161 INT331602 Binding of SSRP1 and Tlr4 1 0.03 0.9 0.21 59.48
162 INT218665 Olr811 Negative_regulation of Phosphorylation of Smad3 1 0.01 0.33 0 59.20
163 INT318922 XIAP Regulation of COMMD1 1 0.09 0.37 0 57.64
164 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27 57.04
165 INT218672 Binding of Ppib and Olr811 1 0.00 0.46 0.08 56.76
166 INT351856 Ccl4 Positive_regulation of Alb 1 0.28 0.4 0.05 56.16
167 INT212584 IFNA1 Regulation of Gene_expression of CD4 1 0.21 0.98 0.03 55.96
168 INT280006 Binding of CLTC and IFNA1 1 0.04 1.59 0 55.72
169 INT343847 IRF6 Positive_regulation of TBCE 1 0.01 1.11 0.87 54.80
170 INT343836 Binding of IRF6 and LBP 1 0.02 0.8 0.14 54.64
171 INT233858 CHKA Positive_regulation of Gene_expression of CDKN1B 1 0.10 0.17 0.09 54.28
172 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32 54.24
173 INT348588 MECP2 Positive_regulation of Gene_expression of EZH2 1 0.28 0.42 0 53.88
174 INT348596 EZH2 Positive_regulation of Gene_expression of MECP2 1 0.28 0.42 0 53.88
175 INT199212 Binding of IGFBP1 and INS 1 0.05 1.77 0.04 53.68
176 INT326048 Gtf3a Positive_regulation of Positive_regulation of Csf2 1 0.04 0.5 0.16 53.12
177 INT343931 Hapln1 Negative_regulation of Tlr4 1 0.12 0.42 0.25 52.88
178 INT341043 Avp Regulation of Camp 1 0.10 0.47 0.03 52.60
179 INT355541 Binding of AMELX and Tnfrsf25 1 0.00 1.36 0 52.24
180 INT355522 Binding of AMELX and HLA-DRB7 1 0.00 1.35 0 52.24
181 INT252777 ROS1 Positive_regulation of Gene_expression of CCL2 1 0.31 0.77 0.23 51.84
182 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 51.64
183 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52 51.64
184 INT228333 Binding of IFNA1 and IRF9 2 0.04 0.53 0.09 51.40
185 INT186502 Binding of AMELX and HLA-A 1 0.00 0.71 0 51.04
186 INT252819 ELANE Positive_regulation of Localization of ROS1 1 0.04 0.05 0 50.48
187 INT241772 AVP Positive_regulation of ADCY1 1 0.09 1.08 0.15 50.44
188 INT178351 Binding of Il6 and Hp 1 0.00 0.61 0.14 50.00
189 INT147785 POMC Positive_regulation of Gene_expression of FUT1 1 0.04 0 0 50.00
190 INT343572 Negative_regulation of Synm Positive_regulation of SLC17A5 1 0.16 0.44 0 50.00
191 INT343861 Binding of IFN1@ and STAT1 1 0.00 0.13 0.14 49.88
192 INT266380 Binding of Tlr2 and Il1 1 0.01 0.76 0.21 49.80
193 INT252794 Binding of IL8 and TNF 1 0.02 0.75 0.25 49.20
194 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25 49.20
195 INT252804 TNF Regulation of Positive_regulation of FOS 1 0.01 0.76 0.25 49.20
196 INT252793 TNF Positive_regulation of Positive_regulation of FOS 1 0.02 0.76 0.25 49.20
197 INT346457 IRF3 Positive_regulation of IFNA1 1 0.03 0.56 0.05 49.04
198 INT252795 IL8 Positive_regulation of Positive_regulation of FOS 1 0.01 0.75 0.25 47.92
199 INT252816 IL8 Regulation of Positive_regulation of FOS 1 0.01 0.75 0.25 47.92
200 INT343845 TICAM1 Positive_regulation of TIRAP 1 0.05 0.25 0.09 47.44

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cirrhosis. They are ordered first by their pain relevance and then by number of times they were reported in Cirrhosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT101105 Positive_regulation of FUT1 62 0.30 55.96 9.28 100.00
2 INT131378 Negative_regulation of FN1 20 0.35 33.98 5.85 100.00
3 INT14470 Gene_expression of HCC 83 0.67 110.55 4.61 100.00
4 INT105923 Binding of FUT1 34 0.14 17.81 4.79 100.00
5 INT83680 Gene_expression of FUT1 40 0.26 25.45 4.98 100.00
6 INT10885 Negative_regulation of C3 9 0.38 11.86 1.35 100.00
7 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 100.00
8 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 100.00
9 INT101103 Positive_regulation of Positive_regulation of FUT1 5 0.27 4.25 0.85 100.00
10 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 100.00
11 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28 100.00
12 INT210391 Negative_regulation of FUT1 5 0.20 5.51 0.23 100.00
13 INT55874 Binding of GPM6A 20 0.34 4.2 13.63 100.00
14 INT6852 Localization of TNF 883 0.81 705.95 270.84 100.00
15 INT8101 Binding of INCENP 42 0.31 16.2 6.68 100.00
16 INT105921 Localization of FUT1 13 0.23 3.92 1.39 100.00
17 INT147788 Regulation of FUT1 11 0.12 7.72 1.44 100.00
18 INT250645 Gene_expression of Samsn1 6 0.33 9.95 0.86 100.00
19 INT176618 Gene_expression of HEY1 29 0.59 36 4.37 100.00
20 INT21487 Negative_regulation of HCC 18 0.49 29.81 1.88 100.00
21 INT210387 Regulation of Binding of FUT1 3 0.13 2.31 0.2 100.00
22 INT187286 Binding of HEY1 17 0.32 31.21 4.52 100.00
23 INT105021 Binding of GOPC 187 0.40 60.39 20.38 100.00
24 INT28009 Positive_regulation of Gene_expression of Ache 15 0.70 5.46 3.26 100.00
25 INT19071 Localization of Ache 66 0.81 5.1 16.27 100.00
26 INT111992 Gene_expression of Pscs 40 0.76 27.47 10.74 100.00
27 INT210403 Phosphorylation of FUT1 2 0.24 0.89 0.09 100.00
28 INT38033 Regulation of HGF 26 0.45 14.96 3.81 100.00
29 INT210361 Negative_regulation of Localization of Actg2 1 0.41 0.81 0 100.00
30 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 100.00
31 INT210405 Negative_regulation of Binding of FUT1 5 0.14 1.97 0.38 100.00
32 INT185754 Negative_regulation of Binding of INCENP 5 0.03 2.01 0.13 100.00
33 INT224442 Negative_regulation of Gene_expression of Pdgfa 2 0.30 2.48 0.5 100.00
34 INT96775 Gene_expression of Pdgfa 42 0.54 29.78 15.46 100.00
35 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 100.00
36 INT184206 Protein_catabolism of HRAS 22 0.66 7.86 1.46 100.00
37 INT136093 Regulation of FBN1 10 0.14 4.39 2.52 100.00
38 INT62854 Positive_regulation of Chp 1 0.21 2.74 0.49 100.00
39 INT615 Regulation of Alb 66 0.62 33.43 15.33 100.00
40 INT5617 Localization of Nppa 266 0.81 83.51 83.89 100.00
41 INT343563 Negative_regulation of Positive_regulation of FUT1 1 0.03 1.19 0.18 100.00
42 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 100.00
43 INT202063 Regulation of Binding of TLR4 2 0.44 2.14 0.47 100.00
44 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 100.00
45 INT227411 Negative_regulation of Positive_regulation of HCC 1 0.02 1.35 0.11 100.00
46 INT11634 Regulation of SERPINE1 24 0.62 20.06 4.26 100.00
47 INT106639 Negative_regulation of Negative_regulation of AVPR2 1 0.29 1.58 0.25 100.00
48 INT22069 Positive_regulation of Localization of Ache 9 0.70 0.61 2.9 100.00
49 INT55276 Regulation of Positive_regulation of Sct 3 0.44 0.92 0.59 100.00
50 INT28802 Binding of F2 15 0.47 8.8 3.47 100.00
51 INT112054 Negative_regulation of Negative_regulation of DMD 12 0.44 5.02 0.45 100.00
52 INT231889 Regulation of Positive_regulation of IAPP 1 0.26 0.55 0 100.00
53 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 99.98
54 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81 99.98
55 INT215517 Gene_expression of Entpd2 3 0.36 3.91 3.63 99.98
56 INT148456 Gene_expression of LY96 7 0.19 4.35 2.02 99.98
57 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13 99.98
58 INT89592 Localization of Ccl5 10 0.61 7.65 3.62 99.98
59 INT110767 Localization of Mcpt1 43 0.68 24.3 16.74 99.98
60 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 99.96
61 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 99.96
62 INT145768 Regulation of TLR4 19 0.45 8.31 2.96 99.96
63 INT312774 Positive_regulation of Gene_expression of Ccl4 3 0.42 1.3 0.1 99.96
64 INT37335 Gene_expression of Nsdhl 45 0.51 24.36 4.58 99.96
65 INT343888 Regulation of Regulation of TLR4 1 0.25 1.34 0.49 99.96
66 INT144158 Negative_regulation of Positive_regulation of AFP 1 0.42 1.66 0.06 99.96
67 INT70242 Localization of HCC 18 0.66 23.95 2.35 99.92
68 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 99.92
69 INT142953 Positive_regulation of Gene_expression of TRPV2 2 0.70 5.56 0.64 99.92
70 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 99.92
71 INT14111 Positive_regulation of Cyp2c22 41 0.67 7.24 17.88 99.92
72 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.92
73 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 99.92
74 INT189322 Binding of A2M 7 0.29 12.1 0.66 99.92
75 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 99.92
76 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 99.92
77 INT252721 Binding of NAFLD2 3 0.03 5.36 0.23 99.92
78 INT166708 Negative_regulation of Protein_catabolism of Col7a1 2 0.32 2.62 0.92 99.92
79 INT123885 Positive_regulation of Lgals3 23 0.57 24.38 6.32 99.92
80 INT252725 Gene_expression of ABCD1 1 0.07 3.29 0.31 99.92
81 INT151526 Regulation of Olfr148 2 0.23 1.93 0.2 99.92
82 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 99.88
83 INT128348 Positive_regulation of Gene_expression of Plod2 1 0.62 1.25 3.28 99.88
84 INT101177 Regulation of COL5A2 12 0.45 4.03 0.62 99.88
85 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51 99.86
86 INT546 Binding of ALB 311 0.48 85.98 60.14 99.86
87 INT66061 Positive_regulation of Gene_expression of AFP 6 0.70 8.67 0.81 99.86
88 INT19537 Negative_regulation of Binding of ALB 6 0.43 3.32 2.26 99.86
89 INT113438 Positive_regulation of GPM6A 3 0.11 3.26 2.29 99.84
90 INT110809 Gene_expression of Mmp1 20 0.75 18 14.49 99.84
91 INT91371 Negative_regulation of STAT3 34 0.59 25 4.08 99.84
92 INT62829 Positive_regulation of VCAM1 39 0.70 38.42 9.15 99.84
93 INT91368 Negative_regulation of Phosphorylation of STAT3 14 0.59 9.22 1.2 99.84
94 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78 99.84
95 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.84
96 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 99.84
97 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 99.84
98 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 99.84
99 INT164656 Negative_regulation of Gene_expression of CD36 24 0.57 6.51 5.39 99.84
100 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 99.84
101 INT135234 Regulation of ETFDH 13 0.29 10.8 3.4 99.84
102 INT89784 Regulation of Transcription of Nos2 14 0.42 8.39 4.24 99.84
103 INT61953 Transcription of Nos2 101 0.72 46.64 25.49 99.84
104 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 99.84
105 INT52688 Transcription of Ptgs2 16 0.69 8.31 7.52 99.84
106 INT3892 Positive_regulation of XDH 8 0.67 8.57 1.5 99.84
107 INT158123 Negative_regulation of Gene_expression of COL5A2 19 0.46 15.27 2.23 99.84
108 INT329275 Localization of TNFRSF17 1 0.15 1.3 0.18 99.84
109 INT82883 Positive_regulation of Ccl2 105 0.69 84.96 42.27 99.84
110 INT6513 Positive_regulation of Gene_expression of BGLAP 24 0.67 11.69 3.96 99.84
111 INT312365 Negative_regulation of Gene_expression of OR11A1 1 0.03 1.27 0 99.84
112 INT12616 Positive_regulation of REG1A 23 0.69 6.57 5.81 99.84
113 INT39874 Positive_regulation of Reg1 12 0.68 5.41 3.8 99.84
114 INT134651 Binding of TLR4 89 0.48 66.96 23.19 99.82
115 INT81495 Positive_regulation of CNR2 28 0.67 14.62 14.27 99.82
116 INT241790 Negative_regulation of AVPR1A 6 0.57 4.62 0.35 99.82
117 INT24029 Regulation of AFP 7 0.44 6.45 0.51 99.82
118 INT20121 Negative_regulation of CYBB 34 0.54 15.5 4.44 99.82
119 INT185908 Gene_expression of COL11A1 4 0.71 6.18 0.25 99.80
120 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.80
121 INT109860 Localization of Actg2 4 0.73 1.61 0.14 99.80
122 INT1901 Binding of Mefv 24 0.48 32.26 4.5 99.80
123 INT10671 Regulation of CRX 4 0.53 6.29 1.78 99.80
124 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 99.78
125 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 99.78
126 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98 99.78
127 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 99.76
128 INT71780 Phosphorylation of TYR 12 0.34 17.21 1.62 99.76
129 INT4922 Negative_regulation of MET 19 0.57 13.97 3.7 99.76
130 INT28110 Transcription of MET 9 0.67 9.43 1.15 99.76
131 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27 99.76
132 INT79140 Binding of HCC 36 0.31 46.96 1.87 99.76
133 INT212449 Negative_regulation of Transcription of MET 1 0.29 5.31 0.06 99.76
134 INT14 Regulation of LDHA 22 0.57 15.26 2.14 99.76
135 INT72372 Positive_regulation of Phosphorylation of Mapk3 30 0.67 13.6 7.69 99.76
136 INT129929 Transcription of LDHA 4 0.17 4.48 0.08 99.76
137 INT20633 Positive_regulation of Gene_expression of LDHA 15 0.49 15.94 1.42 99.76
138 INT99126 Negative_regulation of Positive_regulation of LDHA 4 0.43 4.37 0.32 99.76
139 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 99.76
140 INT111822 Binding of Krt8 6 0.34 4.61 0.39 99.76
141 INT232831 Binding of Krt18 7 0.39 4.61 0.21 99.76
142 INT162557 Binding of MMEL1 2 0.32 3.13 1.03 99.76
143 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3 99.76
144 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 99.76
145 INT132187 Gene_expression of Ecm1 14 0.21 8.12 3.52 99.74
146 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 99.72
147 INT12082 Localization of IL6 365 0.81 241.78 105.78 99.72
148 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 99.72
149 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 99.72
150 INT98944 Gene_expression of ACTA2 14 0.59 11 3.7 99.72
151 INT192423 Positive_regulation of TARM1 5 0.34 10.77 0.51 99.72
152 INT277008 Regulation of Transcription of CYP3A4 1 0.41 0.67 0 99.72
153 INT35584 Binding of ACLY 22 0.35 31.78 7.17 99.72
154 INT64743 Positive_regulation of olt 19 0.40 16.46 3.86 99.72
155 INT46420 Positive_regulation of Gene_expression of Serpina1a 1 0.49 1.17 0.09 99.72
156 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38 99.72
157 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 99.70
158 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79 99.70
159 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82 99.70
160 INT35146 Negative_regulation of PLG 27 0.57 17.63 1.98 99.70
161 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16 99.68
162 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.68
163 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.68
164 INT8743 Positive_regulation of Gcg 19 0.65 10.63 4.43 99.68
165 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.68
166 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 99.68
167 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 99.68
168 INT128349 Gene_expression of Plod2 1 0.69 1.25 3.26 99.68
169 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72 99.68
170 INT169432 Positive_regulation of Vps54 10 0.16 13.96 0.53 99.68
171 INT249100 Positive_regulation of FOXL1 1 0.55 0.99 0.32 99.68
172 INT141381 Gene_expression of SLC25A13 2 0.27 1.77 0.29 99.66
173 INT55740 Gene_expression of Timp1 53 0.75 28.63 13.85 99.64
174 INT173717 Gene_expression of Ccl4 22 0.65 13.98 1.47 99.64
175 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42 99.64
176 INT85078 Positive_regulation of PCNA 36 0.49 17.06 2.81 99.64
177 INT92678 Positive_regulation of Ecm1 30 0.09 28.41 3.68 99.64
178 INT38856 Positive_regulation of Ccl4 24 0.69 9.55 1.62 99.64
179 INT60826 Negative_regulation of Positive_regulation of Ache 3 0.50 0.68 0.73 99.64
180 INT184054 Negative_regulation of Gene_expression of Socs1 7 0.53 9.18 2.22 99.64
181 INT180678 Negative_regulation of Protein_catabolism of Ecm1 6 0.08 2.69 1.61 99.62
182 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 99.60
183 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 99.60
184 INT319472 Phosphorylation of Abcd1 1 0.02 3.12 0.31 99.60
185 INT225694 Negative_regulation of Gene_expression of Entpd2 1 0.27 0.97 0.37 99.60
186 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55 99.58
187 INT40776 Gene_expression of Akt1 99 0.77 34.91 24.39 99.56
188 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 99.56
189 INT210399 Gene_expression of IGF2R 22 0.65 17.1 1.23 99.56
190 INT329274 Localization of TRIM11 1 0.10 1.31 0.18 99.56
191 INT22908 Positive_regulation of Positive_regulation of Gstp1 1 0.65 0.26 0.07 99.56
192 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94 99.54
193 INT93165 Gene_expression of TRPV2 32 0.78 12.49 5.62 99.52
194 INT212444 Positive_regulation of Phosphorylation of TYR 4 0.18 4.83 0.12 99.52
195 INT212446 Negative_regulation of Phosphorylation of TYR 1 0.11 3.4 0.04 99.52
196 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 99.52
197 INT28702 Negative_regulation of F7 6 0.42 3.9 0.63 99.52
198 INT8540 Gene_expression of Serpina1a 5 0.66 3.99 0.34 99.52
199 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 99.50
200 INT103944 Negative_regulation of Synm 3 0.41 2.17 0.83 99.50
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