D:Cleidocranial Dysplasia

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Disease Term
Synonyms Ccd Cleidocranial Dysplasia, Cleidocranial Digital Dysostosis, Cleidocranial Dysostoses, Cleidocranial Dysostosis, Cleidocranial Dysostosis Disorder, Cleidocranial Dysostosis Syndrome, CLEIDOCRANIAL DYSPLASIAS, Cleidocranialis, CLEIDOCRANIOPELVINA, Craniocleidodysostosis, Dysostoses Cleidocranial
Documents 1603
Hot Single Events 200
Hot Interactions 9

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Cleidocranial Dysplasia. They are ordered first by their relevance to Cleidocranial Dysplasia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT255384 Binding of AKR1C2 and DSG1 1 0.01 1.54 0 100.00
2 INT180836 Binding of CTD and NF1 1 0.15 0.2 0 100.00
3 INT196592 Binding of CFD and GHRH 1 0.02 1.88 0.07 99.12
4 INT268342 Binding of APC and ANKS1B 1 0.01 0.92 0 98.52
5 INT267116 Binding of Lmx1b and Nps 1 0.30 1.95 0 95.64
6 INT268396 Binding of BRAF and Ebp 1 0.01 1.72 0 94.80
7 INT252330 Binding of Cd36 and Cd47 2 0.10 0.72 0.19 85.24
8 INT273887 Binding of Jag1 and Notch2 1 0.02 1.06 0 80.80
9 INT188198 OSM Positive_regulation of STAT3 1 0.52 0.24 0.12 80.56
10 INT352896 PTGDS Positive_regulation of Gene_expression of ROS1 1 0.12 0.91 0.18 78.64
11 INT174104 Binding of HSPG2 and Ache 1 0.16 0.98 0.09 78.16
12 INT282879 Binding of MUC5AC and RHCE 1 0.00 0.36 0 77.96
13 INT289793 Binding of Comp and Ecm1 1 0.05 2.5 0.12 76.92
14 INT289790 Binding of Col7a1 and Comp 1 0.14 1.2 0.12 76.92
15 INT289794 Binding of Comp and Fn1 1 0.07 2.59 0.12 76.92
16 INT255256 Positive_regulation of Binding of Rb1 and Tsp1 1 0.50 0.48 0.08 75.48
17 INT255255 Binding of Nsg1 and Tsp1 1 0.08 0.48 0.08 75.04
18 INT255258 Binding of Rb1 and Tsp1 1 0.38 0.95 0.15 74.04
19 INT188209 OSM Positive_regulation of MAPK1 1 0.35 0.47 0.27 73.68
20 INT197794 Negative_regulation of Pthlh Regulation of Ihh 1 0.36 1.33 0 73.60
21 INT197793 Pthlh Regulation of Ihh 1 0.22 1.32 0 73.60
22 INT225805 Binding of SNRNP70 and Enpp1 1 0.42 1.43 0.09 72.40
23 INT225808 SNRNP70 Regulation of Enpp1 1 0.30 0.71 0.04 72.40
24 INT225774 SNRNP70 Regulation of Binding of Insr and Enpp1 1 0.03 0.77 0.04 72.40
25 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09 66.76
26 INT279110 COMP Regulation of Localization of MATN3 1 0.59 0.45 0 66.56
27 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09 65.44
28 INT225800 Binding of Insr and Enpp1 1 0.05 0.67 0.04 64.72
29 INT279107 Binding of COMP and MATN3 1 0.41 1.43 0.2 60.80
30 INT279109 Binding of COL9A2 and MATN3 1 0.48 0.64 0.1 60.80
31 INT255385 Binding of COL1A2 and DSPP 1 0.40 0.12 0 60.64
32 INT203638 Binding of MR1 and GOPC 1 0.04 1.43 0.05 60.56
33 INT289788 Binding of Comp and Scn8a 1 0.16 1.37 0 60.04
34 INT197552 GSTK1 Positive_regulation of NQO1 1 0.09 1.06 0 59.24
35 INT320267 CCNA2 Positive_regulation of CDK1 1 0.12 1.08 0.08 58.28
36 INT191612 Nf1 Positive_regulation of ras 1 0.25 2.6 0.11 57.44
37 INT35363 Binding of GH1 and GHRH 2 0.36 0.94 0.36 56.96
38 INT78445 Binding of GHRH and IGF1 1 0.20 0.72 0.06 56.96
39 INT312290 Binding of Col9a1 and Matn3 1 0.02 0.65 0 56.08
40 INT259095 Binding of RBBP8 and LMO4 1 0.15 0.73 0 52.88
41 INT259093 Binding of TSC1 and LMO4 1 0.02 0.74 0 52.88
42 INT259091 Binding of BRCA1 and LMO4 1 0.24 0.74 0 52.88
43 INT183646 Negative_regulation of Ppp1r14b Positive_regulation of Macf1 1 0.00 1.29 0.38 51.52
44 INT289789 Comp Positive_regulation of Gene_expression of Rer1 1 0.55 0.8 0.03 51.20
45 INT183645 Ppp1r14b Positive_regulation of Macf1 1 0.00 1.23 0.38 51.16
46 INT183647 Dss1 Positive_regulation of Macf1 1 0.01 1.23 0.38 50.72
47 INT303600 IGF1 Regulation of Gene_expression of GH1 1 0.39 0.83 0.14 50.16
48 INT267119 Lmx1b Regulation of Regulation of Col4a1 1 0.09 0.67 0 48.80
49 INT225802 Binding of Enpp1 and Ppi-rs 1 0.04 1 0.03 48.08
50 INT197547 Binding of PTS and KEAP1 1 0.08 1.23 0 48.08
51 INT324016 Binding of Dclk1 and Tff2 1 0.34 0.92 0 46.80
52 INT324015 Binding of Dclk1 and Spem1 1 0.06 0.92 0 46.80
53 INT255260 Binding of Cd47 and Tsp1 1 0.20 1.42 0.67 43.80
54 INT32030 Binding of CEL and ERLEC1 1 0.08 0.42 0.1 43.12
55 INT268398 Binding of LRP1 and Wnt2 1 0.01 0.36 0 43.12
56 INT312289 Binding of Col9a1 and Comp 1 0.09 1.38 0 42.76
57 INT312291 Binding of Comp and Matn3 1 0.06 1.37 0 42.76
58 INT267117 Lmx1b Regulation of Col7a1 1 0.02 1.29 0 40.68
59 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08 39.68
60 INT267118 Lmx1b Regulation of Regulation of Col7a1 1 0.06 0.47 0 39.28
61 INT255261 Tsp1 Positive_regulation of Binding of Cd47 1 0.27 0.5 0.23 38.52
62 INT267115 Lmx1b Regulation of Gene_expression of Col4a1 1 0.09 1.37 0 37.64
63 INT191614 Adcyap1 Positive_regulation of Rtcd1 1 0.01 0.93 0 34.52
64 INT267257 BCL11B Regulation of Transcription of BMI1 1 0.28 0.74 0 33.44
65 INT267259 BCL11B Regulation of BMI1 1 0.65 1.48 0 32.80
66 INT265964 TNNI2 Regulation of CA2 1 0.22 0.09 0 32.32
67 INT277656 Igf1 Positive_regulation of Igfbp3 1 0.01 0.4 0.34 31.04
68 INT286650 Binding of IGHG3 and OLR1 1 0.01 0.42 0 29.12
69 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09 27.20
70 INT286653 Binding of CD40LG and OLR1 1 0.08 0.41 0 27.20
71 INT232005 Binding of Cd36 and Tsp1 2 0.25 1.81 0.16 25.76
72 INT35157 GH1 Regulation of GHRH 3 0.17 0.5 0.99 25.00
73 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 25.00
74 INT78446 Binding of GH1 and IGFBP3 1 0.11 0.48 0.1 25.00
75 INT258173 Negative_regulation of Cpox Negative_regulation of Gene_expression of Gtf3a 1 0.00 1.44 0.33 23.68
76 INT267261 GOPC Regulation of BMI1 1 0.06 0.75 0 22.52
77 INT286113 Binding of Fap and Rpe65 1 0.04 1.97 0 21.32
78 INT286110 Binding of Rpe65 and Gopc 1 0.01 1.97 0 21.32
79 INT289795 Binding of COMP and Comp 1 0.02 0.99 0 18.72
80 INT173659 Map2k3 Positive_regulation of MAPK8 1 0.15 0.28 0.07 18.48
81 INT173660 Map2k6 Positive_regulation of MAPK8 1 0.15 0.27 0.07 18.28
82 INT310186 Binding of Gdf2 and Bmpr2 1 0.02 0 0 15.60
83 INT310189 Binding of Acvrl1 and Gdf2 1 0.01 0 0 15.60
84 INT268397 Binding of Kras and Regulation of ARAF 1 0.03 1.16 0 11.36
85 INT320699 Gene_expression of Ptger2 Negative_regulation of Gene_expression of IL2 1 0.00 1.1 0.35 6.56
86 INT337811 Gene_expression of Gsk3b Positive_regulation of Phosphorylation of Akt1 1 0.37 0.37 0.03 6.24
87 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
88 INT229394 TPSD1 Positive_regulation of F2RL1 2 0.00 3.11 2.14 5.00
89 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
90 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65 5.00
91 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5 5.00
92 INT107858 PRSS1 Positive_regulation of F2RL1 6 0.12 4.23 1.29 5.00
93 INT262336 Binding of Abat and Tmem132a 1 0.00 1.39 1.14 5.00
94 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94 5.00
95 INT107001 F2 Positive_regulation of PAR1 4 0.05 2.15 0.92 5.00
96 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87 5.00
97 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87 5.00
98 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73 5.00
99 INT106999 F2 Positive_regulation of PAR4 3 0.06 1.83 0.72 5.00
100 INT106992 F2 Positive_regulation of PARD3 3 0.05 1.83 0.72 5.00
101 INT171901 Binding of TNF and Il1 2 0.18 1.07 0.7 5.00
102 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61 5.00
103 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 5.00
104 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55 5.00
105 INT133049 TNF Positive_regulation of ICAM1 4 0.47 2.49 0.54 5.00
106 INT352891 Binding of ROS1 and GOPC 1 0.09 1.34 0.53 5.00
107 INT309953 Binding of Atrn and Nav1 1 0.00 0.23 0.53 5.00
108 INT232424 VIP Positive_regulation of Localization of PRL 1 0.36 0 0.53 5.00
109 INT324523 Tlr4 Regulation of Gene_expression of PGE 1 0.23 1.98 0.51 5.00
110 INT292873 Binding of Fas and Fasl 5 0.26 15.74 0.49 5.00
111 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47 5.00
112 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45 5.00
113 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45 5.00
114 INT225775 Enpp1 Positive_regulation of Ppi-rs 1 0.06 2.49 0.44 5.00
115 INT188194 OSM Regulation of IL6 1 0.16 1.12 0.43 5.00
116 INT188205 OSM Regulation of LIF 1 0.09 1.12 0.43 5.00
117 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43 5.00
118 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43 5.00
119 INT302369 Binding of Arx and Dlx1 1 0.34 0 0.43 5.00
120 INT191610 Binding of App and Drd3 1 0.20 0.7 0.42 5.00
121 INT303857 DDR1 Positive_regulation of IL8 1 0.05 1.5 0.42 5.00
122 INT303858 DDR1 Positive_regulation of CXCR2 1 0.11 1.5 0.42 5.00
123 INT327727 Atp6v0a2 Negative_regulation of Gene_expression of Kit 1 0.05 0.83 0.41 5.00
124 INT171990 Binding of DMD and VDR 5 0.05 2.58 0.39 5.00
125 INT350814 Negative_regulation of TNF Positive_regulation of Gene_expression of Cpox 1 0.06 1.33 0.37 5.00
126 INT232422 VIP Regulation of Gene_expression of PRL 1 0.40 0 0.37 5.00
127 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37 5.00
128 INT350816 TNF Positive_regulation of Gene_expression of Cpox 1 0.05 1.33 0.37 5.00
129 INT302371 Dlx1 Regulation of Gene_expression of Arx 1 0.28 0 0.35 5.00
130 INT183786 IL6 Negative_regulation of INS 1 0.09 1.61 0.35 5.00
131 INT183784 INS Negative_regulation of Binding of TBK1 1 0.01 1.81 0.34 5.00
132 INT183783 INS Negative_regulation of TBK1 1 0.01 1.81 0.34 5.00
133 INT183793 INS Negative_regulation of Binding of Ros1 1 0.16 1.66 0.34 5.00
134 INT183785 INS Positive_regulation of Gene_expression of NFKBIB 1 0.03 1.83 0.34 5.00
135 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34 5.00
136 INT183780 INS Negative_regulation of Gene_expression of CYBB 1 0.02 1.74 0.34 5.00
137 INT183782 INS Negative_regulation of Gene_expression of TBK1 1 0.01 1.81 0.34 5.00
138 INT188204 Negative_regulation of IL6 Positive_regulation of STAT3 1 0.28 0.54 0.34 5.00
139 INT232419 ABAT Positive_regulation of Localization of PRL 1 0.09 0 0.33 5.00
140 INT324525 PGE Positive_regulation of Positive_regulation of Egfr 1 0.41 1.05 0.33 5.00
141 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33 5.00
142 INT324522 PGE Positive_regulation of Phosphorylation of Egfr 1 0.56 1.04 0.33 5.00
143 INT324524 PGE Positive_regulation of Egfr 1 0.38 1.05 0.33 5.00
144 INT232425 Binding of ABAT and Positive_regulation of PRL 1 0.09 0.15 0.33 5.00
145 INT324527 PGE Positive_regulation of Egfr Positive_regulation of Phosphorylation of Egfr 1 0.38 1.05 0.33 5.00
146 INT232420 PRL Positive_regulation of Regulation of ABAT 1 0.09 0 0.33 5.00
147 INT191616 Binding of Cbln1 and Nf1 1 0.01 0.2 0.32 5.00
148 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32 5.00
149 INT239573 Binding of DPF1 and AIS 1 0.02 0.74 0.31 5.00
150 INT191611 Nf1 Regulation of ras 1 0.26 0.18 0.3 5.00
151 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29 5.00
152 INT225794 Il1 Negative_regulation of Gene_expression of Npp 1 0.02 0.99 0.28 5.00
153 INT225777 Il1 Negative_regulation of Npp 1 0.02 0.99 0.28 5.00
154 INT101813 KEAP1 Negative_regulation of NFE2L2 3 0.47 1.63 0.28 5.00
155 INT225776 Enpp1 Positive_regulation of Positive_regulation of Ppi-rs 1 0.08 1.67 0.28 5.00
156 INT225798 Il1 Negative_regulation of Gene_expression of Ppi-rs 1 0.01 1 0.28 5.00
157 INT225796 Il1 Negative_regulation of Ppi-rs 1 0.01 1 0.28 5.00
158 INT352894 Negative_regulation of Binding of ROS1 and GOPC 1 0.08 0.67 0.28 5.00
159 INT225784 Il1 Negative_regulation of Gene_expression of Enpp1 1 0.08 0.99 0.28 5.00
160 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27 5.00
161 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26 5.00
162 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26 5.00
163 INT352895 Positive_regulation of Binding of ROS1 and GOPC 1 0.08 0.68 0.26 5.00
164 INT262354 TRIP10 Negative_regulation of Cyp4a3 1 0.00 0.8 0.26 5.00
165 INT239570 Binding of PDGFC and AIS 1 0.04 0.9 0.26 5.00
166 INT262353 TRIP10 Negative_regulation of Cyp1a2 1 0.03 0.8 0.26 5.00
167 INT262329 TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 5.00
168 INT262330 Positive_regulation of TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 5.00
169 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26 5.00
170 INT241401 VEGFA Positive_regulation of Gene_expression of Gopc 1 0.11 0.85 0.25 5.00
171 INT352890 Binding of PTGDS and ROS1 1 0.13 0.67 0.25 5.00
172 INT239572 DPF1 Positive_regulation of AIS 1 0.02 0.71 0.24 5.00
173 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24 5.00
174 INT191619 Binding of App and Flna 1 0.04 0.18 0.24 5.00
175 INT188200 IL6ST Positive_regulation of STAT3 1 0.25 0.38 0.23 5.00
176 INT302367 Dlx2 Regulation of Gene_expression of Arx 1 0.59 0.23 0.22 5.00
177 INT188195 GOPC Positive_regulation of MAPK1 2 0.21 0.32 0.22 5.00
178 INT188203 EGF Positive_regulation of Protein_catabolism of OSM 1 0.30 0.17 0.21 5.00
179 INT182606 Binding of MSH2 and MSH3 1 0.12 1.4 0.21 5.00
180 INT188201 OSM Positive_regulation of Phosphorylation of STAT3 1 0.40 0.24 0.21 5.00
181 INT183644 Nos2 Positive_regulation of Gene_expression of Macf1 1 0.05 0.84 0.21 5.00
182 INT255257 Binding of Serpine1 and Tsp1 1 0.07 0.85 0.2 5.00
183 INT255259 Binding of Plg and Tsp1 1 0.05 0.84 0.2 5.00
184 INT225787 Ppi-rs Positive_regulation of Gene_expression of Ank 1 0.06 1.44 0.19 5.00
185 INT302372 Arx Negative_regulation of Gene_expression of Calb2 1 0.13 0.05 0.18 5.00
186 INT191609 Binding of Drd3 and Flna 1 0.06 0.42 0.17 5.00
187 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17 5.00
188 INT191621 Binding of Drd3 and Nf1 1 0.32 0.53 0.17 5.00
189 INT191337 Binding of IDO1 and GOPC 1 0.01 0.65 0.16 5.00
190 INT191336 Binding of TSPO and GOPC 1 0.01 0.65 0.16 5.00
191 INT188199 IL6 Positive_regulation of MAPK1 1 0.27 0.25 0.16 5.00
192 INT191338 Binding of TSPO and IDO1 1 0.02 0.65 0.16 5.00
193 INT350815 Negative_regulation of Binding of TNF and Il1 1 0.05 0.37 0.16 5.00
194 INT298717 Fgf2 Positive_regulation of Gene_expression of PDGFA 1 0.01 0.23 0.15 5.00
195 INT239081 Binding of GH1 and MAS1 1 0.03 1.41 0.15 5.00
196 INT298716 Ngf Positive_regulation of Gene_expression of PDGFA 1 0.01 0.22 0.15 5.00
197 INT310263 Rb1 Negative_regulation of Gene_expression of Tnf 1 0.07 0.97 0.15 5.00
198 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 5.00
199 INT225778 Igf1 Negative_regulation of Positive_regulation of Ppi-rs 1 0.01 0.82 0.14 5.00
200 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Cleidocranial Dysplasia. They are ordered first by their pain relevance and then by number of times they were reported in Cleidocranial Dysplasia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT258944 Negative_regulation of OFD1 1 0.23 6.08 0 100.00
2 INT258950 Gene_expression of OFD1 1 0.37 7.19 0 100.00
3 INT220533 Positive_regulation of OFD1 2 0.27 6.58 0.08 100.00
4 INT139108 Gene_expression of Hgd 3 0.38 4.69 0.6 100.00
5 INT258946 Binding of OFD1 1 0.20 5.35 0 100.00
6 INT258948 Positive_regulation of Gene_expression of OFD1 1 0.27 5.05 0 100.00
7 INT160852 Regulation of CD55 5 0.16 5.28 0.56 100.00
8 INT134338 Gene_expression of CD55 23 0.65 13.01 1.38 100.00
9 INT258947 Regulation of OFD1 1 0.25 3.47 0 100.00
10 INT214618 Transcription of FLNA 4 0.51 8.06 0.37 100.00
11 INT36777 Gene_expression of CTD 12 0.41 11.47 1.42 100.00
12 INT258949 Localization of OFD1 2 0.41 3.87 0 100.00
13 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
14 INT234962 Positive_regulation of Gene_expression of DSG1 5 0.48 5.41 0.37 100.00
15 INT140647 Gene_expression of DSG1 45 0.75 27.95 1.33 100.00
16 INT167750 Positive_regulation of Gene_expression of DSPP 2 0.50 3.13 0 100.00
17 INT160851 Regulation of Hgd 1 0.03 1.66 0.25 100.00
18 INT28647 Binding of CTD 13 0.31 14.2 1.5 100.00
19 INT61993 Gene_expression of NF1 29 0.78 34.47 1.23 100.00
20 INT12628 Binding of Cish 4 0.30 2.45 0.78 100.00
21 INT2102 Gene_expression of Rhd 7 0.51 1.37 1.93 100.00
22 INT80174 Positive_regulation of Gene_expression of Neu1 23 0.37 17.82 1.12 100.00
23 INT336270 Localization of AKR1C1 1 0.06 1.56 0.29 100.00
24 INT14470 Gene_expression of HCC 83 0.67 110.55 4.61 100.00
25 INT68216 Binding of NF1 40 0.48 51.24 4.59 99.96
26 INT178763 Binding of HHIP 37 0.08 6.3 5.29 99.96
27 INT2250 Binding of REG3A 3 0.47 3.58 1.33 99.96
28 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55 99.92
29 INT234950 Binding of DSG1 29 0.36 23.67 0.69 99.92
30 INT142123 Positive_regulation of Gene_expression of Runx2 17 0.64 4.81 0.65 99.92
31 INT180839 Binding of ARSK 1 0.25 0.28 0 99.92
32 INT237743 Gene_expression of Dclk1 3 0.70 17.9 0.24 99.84
33 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 99.84
34 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57 99.84
35 INT267269 Gene_expression of BCL11B 62 0.78 48.75 0.55 99.80
36 INT267279 Positive_regulation of Gene_expression of BCL11B 1 0.70 14.02 0 99.80
37 INT156794 Gene_expression of CISH 41 0.58 23.09 5.03 99.80
38 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 99.76
39 INT125727 Positive_regulation of FGF23 5 0.69 4.04 0.53 99.70
40 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 99.68
41 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 99.68
42 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 99.68
43 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 99.64
44 INT174112 Positive_regulation of Gene_expression of KRT19 4 0.44 4.28 0.31 99.64
45 INT232945 Positive_regulation of Gene_expression of KRT18 2 0.49 3.54 0.23 99.64
46 INT232967 Positive_regulation of Gene_expression of KRT8 2 0.29 3.54 0.23 99.64
47 INT148121 Gene_expression of KRT8 35 0.65 29.07 1.05 99.64
48 INT83479 Gene_expression of KRT18 30 0.65 27.29 1 99.64
49 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 99.64
50 INT169987 Transcription of GOPC 45 0.60 21.88 2.61 99.56
51 INT132951 Regulation of GJA1 2 0.57 0.79 0.24 99.56
52 INT259113 Gene_expression of LMO4 1 0.78 71.49 0.76 99.52
53 INT45510 Binding of Scn8a 4 0.31 3.89 0.25 99.52
54 INT71763 Gene_expression of Mri1 33 0.58 12.56 8.6 99.44
55 INT255251 Negative_regulation of Smad2 12 0.32 5.69 1.44 99.44
56 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.42
57 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.42
58 INT71820 Binding of PDXP 4 0.30 3.87 0.93 99.32
59 INT50077 Gene_expression of Myb 21 0.66 7.68 1.54 99.32
60 INT258945 Positive_regulation of KRT18 2 0.21 4.52 0 99.28
61 INT139399 Regulation of Gene_expression of PCNA 14 0.56 6.06 0.43 99.26
62 INT139391 Regulation of PCNA 10 0.60 3.12 0.33 99.26
63 INT97909 Binding of COMP 13 0.37 5.98 1.22 99.20
64 INT3364 Binding of SGCG 87 0.47 31.93 17.24 99.20
65 INT71389 Positive_regulation of KRT19 3 0.38 4.91 0.13 99.14
66 INT142118 Regulation of Gene_expression of Runx2 2 0.61 2.92 0 99.12
67 INT148562 Positive_regulation of GNAS 13 0.16 5.31 1.32 99.10
68 INT197143 Positive_regulation of Renbp 15 0.33 9.41 1.31 99.00
69 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 98.96
70 INT164349 Positive_regulation of KRT8 2 0.10 3.14 0.08 98.92
71 INT247998 Negative_regulation of SNORA73A 2 0.41 0.85 0.12 98.92
72 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 98.84
73 INT265814 Localization of Runx2 1 0.75 0.84 0 98.82
74 INT66225 Positive_regulation of COX18 9 0.37 4 1.86 98.80
75 INT66227 Gene_expression of COX18 41 0.50 26.91 6.26 98.80
76 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 98.76
77 INT176264 Binding of PCNA 21 0.21 9.08 0.51 98.72
78 INT232798 Positive_regulation of Gene_expression of Shh 7 0.70 1.49 0.44 98.72
79 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77 98.72
80 INT167751 Gene_expression of DSPP 15 0.77 8.56 0.24 98.70
81 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 98.64
82 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 98.64
83 INT118097 Localization of COMP 18 0.70 9.99 1.42 98.64
84 INT279130 Negative_regulation of Localization of COMP 5 0.51 3.75 0.69 98.64
85 INT339529 Gene_expression of Eaf2 1 0.01 0.75 0 98.64
86 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 98.60
87 INT101163 Gene_expression of we 1 0.00 1.13 0.4 98.60
88 INT31719 Negative_regulation of Ctsa 6 0.47 6.1 1.43 98.56
89 INT121347 Binding of GNAS 8 0.13 3.99 1.47 98.54
90 INT78199 Gene_expression of Neu1 65 0.75 62.88 7.16 98.48
91 INT84510 Positive_regulation of Nf1 8 0.69 9.52 1.93 98.48
92 INT339530 Regulation of Eaf2 1 0.00 0.76 0.1 98.48
93 INT131645 Negative_regulation of Nf1 10 0.58 8.12 1.24 98.48
94 INT232994 Gene_expression of KRT10 6 0.40 8.2 0.03 98.38
95 INT70615 Binding of TXNRD1 25 0.36 12.15 1.27 98.36
96 INT192961 Positive_regulation of Negative_regulation of ERBB2 2 0.64 3.53 0.06 98.32
97 INT167085 Negative_regulation of ERBB2 67 0.57 44.6 1.48 98.32
98 INT1361 Negative_regulation of Gnrhr 118 0.58 57.77 35.54 98.32
99 INT14562 Negative_regulation of Igfbp1 7 0.26 4.32 1.5 98.32
100 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71 98.28
101 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 98.12
102 INT125586 Gene_expression of Stmn1 13 0.75 8.28 0.42 98.12
103 INT235362 Gene_expression of SNORA73A 8 0.75 4.09 0 98.12
104 INT112054 Negative_regulation of Negative_regulation of DMD 12 0.44 5.02 0.45 98.12
105 INT125587 Positive_regulation of Gene_expression of Stmn1 9 0.67 4.2 0.08 98.12
106 INT248001 Positive_regulation of Gene_expression of SNORA73A 1 0.49 2.51 0 98.12
107 INT5793 Binding of CTS 110 0.48 63.91 40.62 98.10
108 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 98.08
109 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73 98.06
110 INT251080 Gene_expression of Areg 5 0.60 8.16 0.42 98.04
111 INT69743 Gene_expression of Hmox2 36 0.78 20.77 14.26 97.96
112 INT132521 Gene_expression of BRAF 14 0.65 13.59 0.73 97.94
113 INT38672 Binding of KRT20 69 0.39 48.01 6.31 97.88
114 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 97.88
115 INT197681 Binding of CHDH 40 0.48 33.72 2.13 97.84
116 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 97.80
117 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 97.80
118 INT324004 Regulation of Spem1 1 0.04 0.48 0 97.80
119 INT105021 Binding of GOPC 187 0.40 60.39 20.38 97.76
120 INT239085 Binding of KAT2B 1 0.18 2.04 0.09 97.76
121 INT239082 Binding of BCAM 1 0.03 2.03 0.09 97.76
122 INT144700 Gene_expression of Kras 21 0.41 12.28 0.57 97.74
123 INT324006 Regulation of Gene_expression of Dclk1 1 0.21 0.95 0 97.64
124 INT37380 Negative_regulation of Sis 31 0.55 19.89 3.92 97.56
125 INT100622 Localization of CD68 16 0.73 6.58 2.2 97.52
126 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35 97.52
127 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51 97.52
128 INT74272 Localization of CPOX 39 0.63 25.12 10.53 97.52
129 INT100620 Localization of VIM 8 0.76 5.47 2.16 97.52
130 INT100621 Localization of HLA-DRA 7 0.40 2.86 1.2 97.52
131 INT100623 Localization of ACTA2 2 0.27 2.97 0.25 97.52
132 INT162393 Gene_expression of SMUG1 58 0.75 38.78 7.7 97.48
133 INT185896 Gene_expression of AREG 11 0.29 9.45 0.28 97.48
134 INT310680 Gene_expression of ARSB 1 0.64 6.28 0.12 97.48
135 INT32034 Binding of LOH19CR1 9 0.23 6.55 0.62 97.32
136 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59 97.32
137 INT173629 Binding of WISP3 1 0.11 0.1 0 97.28
138 INT173643 Binding of WISP1 1 0.08 0.1 0 97.28
139 INT135879 Localization of MATN3 12 0.80 10.31 1.44 97.12
140 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74 97.12
141 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 97.12
142 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 97.04
143 INT12474 Regulation of INSRR 18 0.29 6.29 4.81 97.04
144 INT125980 Binding of CFD 8 0.42 10.96 1.39 96.92
145 INT25123 Negative_regulation of COL7A1 42 0.58 19.98 5.96 96.84
146 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 96.84
147 INT164066 Negative_regulation of SIL1 3 0.21 2.75 0.96 96.78
148 INT128030 Gene_expression of GJA1 23 0.75 7.81 1.88 96.76
149 INT277651 Positive_regulation of Localization of Igfbp1 1 0.27 0.85 0.79 96.68
150 INT116728 Negative_regulation of ARSH 9 0.13 9.67 0.27 96.64
151 INT105991 Negative_regulation of IDS 12 0.38 6.31 1.04 96.64
152 INT75315 Regulation of Ghr 4 0.22 1.5 1.34 96.64
153 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 96.40
154 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78 96.40
155 INT82829 Gene_expression of COMP 104 0.78 57 9.81 96.32
156 INT63270 Gene_expression of Ncor1 7 0.56 0.65 0.15 96.32
157 INT102760 Gene_expression of AKAP3 1 0.65 1.25 0 96.24
158 INT102761 Gene_expression of TRAF7 1 0.01 1.25 0 96.24
159 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 96.16
160 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 96.16
161 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 96.12
162 INT215117 Gene_expression of Ctsa 14 0.33 8.66 1.18 96.04
163 INT255194 Binding of Fbn1 2 0.35 4.26 0.34 96.00
164 INT142117 Regulation of Runx2 6 0.61 2.75 0.22 96.00
165 INT152340 Negative_regulation of Shox2 1 0.59 2.18 1.34 96.00
166 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 96.00
167 INT237257 Gene_expression of Rhbdl1 3 0.67 5.15 4.31 95.96
168 INT237259 Positive_regulation of Gene_expression of Rhbdl1 1 0.50 3.58 0 95.96
169 INT309973 Negative_regulation of Pkp2 1 0.40 0.4 0.09 95.92
170 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26 95.92
171 INT91890 Positive_regulation of Kit 36 0.50 25.44 3.06 95.88
172 INT112124 Positive_regulation of Egfr 71 0.70 47.82 5.61 95.80
173 INT62296 Gene_expression of PDXP 8 0.67 6.48 1.44 95.76
174 INT324008 Gene_expression of Msi1 1 0.13 2.72 0.29 95.72
175 INT20264 Gene_expression of Chkb 29 0.46 13.14 13.65 95.68
176 INT9318 Localization of Igfbp1 2 0.32 1.39 1.12 95.60
177 INT101590 Gene_expression of SERPINB5 8 0.75 9.35 1.19 95.56
178 INT64844 Protein_catabolism of PMEL 1 0.75 0.22 0.05 95.32
179 INT82742 Gene_expression of Tff2 3 0.75 7.06 0.44 95.24
180 INT183125 Negative_regulation of SULF1 2 0.42 2.26 0.13 95.16
181 INT82686 Gene_expression of Sparc 4 0.75 6.14 2.34 95.04
182 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 95.04
183 INT2541 Binding of Calca 200 0.48 67.14 134.62 95.00
184 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 95.00
185 INT174100 Gene_expression of YWHAE 14 0.31 12.42 0.08 95.00
186 INT63113 Positive_regulation of HRAS 30 0.67 22.85 4.28 94.96
187 INT175422 Positive_regulation of SACM1L 1 0.00 2.11 0 94.92
188 INT2512 Negative_regulation of Cp 27 0.51 10.15 8.37 94.88
189 INT49436 Binding of TRPV1 145 0.48 38.35 55.08 94.76
190 INT76227 Binding of NPC1 30 0.41 32.31 4.05 94.76
191 INT14043 Binding of HP 52 0.30 26.56 7.76 94.40
192 INT28809 Regulation of CXCL1 3 0.53 3.21 1.07 94.32
193 INT59899 Regulation of MATN3 4 0.45 7.61 1.6 94.28
194 INT46281 Binding of Calm1 8 0.48 5.54 5.22 94.28
195 INT118095 Regulation of COMP 7 0.43 9.69 3.33 94.28
196 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 94.24
197 INT82798 Regulation of MYC 19 0.60 12.06 2.31 94.16
198 INT255240 Regulation of Nsg1 2 0.22 0.42 0.64 94.16
199 INT145520 Positive_regulation of Dss1 16 0.39 14.04 3.38 94.04
200 INT354380 Regulation of CXCL2 1 0.22 1.91 0.47 94.04
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