D:Clonorchiasis

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Disease Term
Synonyms Clonorchiases, Oriental Liver Fluke, ORIENTAL LIVER FLUKES
Documents 10
Hot Single Events 3
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Clonorchiasis. They are ordered first by their relevance to Clonorchiasis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT304169 Il33 Positive_regulation of Gene_expression of Itgam 1 0.02 1.18 0.15 5.00
2 INT304172 Il5 Positive_regulation of Bcl2l1 1 0.02 0.91 0.05 5.00
3 INT304170 Binding of Apaf1 and Positive_regulation of Casp9 1 0.01 0.51 0 5.00
4 INT304175 IL1B Positive_regulation of Gene_expression of Vcam1 1 0.02 0.96 0 5.00
5 INT304135 Binding of CEL and Positive_regulation of CASP8 1 0.00 0.52 0 5.00
6 INT285291 TNF Positive_regulation of Gene_expression of Vcam1 2 0.10 3.1 0 5.00
7 INT304176 Binding of IL1B and Il13 1 0.00 0.96 0 5.00
8 INT304167 Il4 Positive_regulation of Gene_expression of Vcam1 1 0.04 0.94 0 5.00
9 INT304168 Binding of Gata1 and Sfpi1 1 0.08 0.07 0 5.00
10 INT304171 Il13 Positive_regulation of Gene_expression of Vcam1 1 0.04 0.89 0 5.00
11 INT304174 Binding of IL1B and Il4 1 0.00 0.96 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Clonorchiasis. They are ordered first by their pain relevance and then by number of times they were reported in Clonorchiasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT246513 Regulation of IL4I1 2 0.10 2.06 0.15 98.44
2 INT94535 Negative_regulation of Gene_expression of MT2A 1 0.34 1.7 0.07 83.76
3 INT94534 Gene_expression of MT2A 8 0.75 11.28 1.76 83.24
4 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15 75.00
5 INT296120 Binding of SDCBP 1 0.36 1.16 0 73.76
6 INT296126 Negative_regulation of Gene_expression of MTNR1A 2 0.21 0.77 0.11 67.80
7 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 67.44
8 INT122656 Gene_expression of MTNR1A 21 0.75 6.37 2.46 66.48
9 INT248744 Negative_regulation of STH 2 0.41 1.02 0 62.28
10 INT10303 Regulation of STH 16 0.60 16.14 0.95 53.88
11 INT143664 Gene_expression of ST2 9 0.77 5.03 1.73 50.00
12 INT124940 Binding of MTNR1A 8 0.36 2.29 0.9 50.00
13 INT275637 Positive_regulation of Gene_expression of MT2A 2 0.28 2.49 0.6 50.00
14 INT226490 Localization of ST2 5 0.31 1.99 0.44 50.00
15 INT295943 Negative_regulation of MTNR1A 4 0.21 2.66 0.24 50.00
16 INT94531 Transcription of MT2A 2 0.56 1.52 0.07 50.00
17 INT296123 Negative_regulation of Transcription of MT2A 1 0.13 0.44 0 50.00
18 INT296121 Phosphorylation of ST2 1 0.08 0.2 0 50.00
19 INT296119 Negative_regulation of Transcription of MTNR1A 1 0.07 0.44 0 50.00
20 INT296122 Regulation of Binding of SDCBP 1 0.44 0.51 0 50.00
21 INT296125 Regulation of Gene_expression of MT2A 1 0.14 0.49 0 50.00
22 INT296124 Transcription of MTNR1A 1 0.11 0.44 0 50.00
23 INT153162 Gene_expression of SDCBP 2 0.65 0.8 0 50.00
24 INT296127 Negative_regulation of MT2A 1 0.06 0.43 0 50.00
25 INT80939 Positive_regulation of PDR 8 0.55 5.43 0.67 15.92
26 INT246512 Positive_regulation of IL4I1 2 0.26 1.05 0 15.92
27 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 7.44
28 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 6.60
29 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
30 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
31 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
32 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
33 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
34 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
35 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
36 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 5.00
37 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 5.00
38 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 5.00
39 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 5.00
40 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32 5.00
41 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 5.00
42 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 5.00
43 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 5.00
44 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 5.00
45 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7 5.00
46 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 5.00
47 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 5.00
48 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36 5.00
49 INT63361 Gene_expression of CD44 126 0.77 71.58 12.96 5.00
50 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87 5.00
51 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39 5.00
52 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08 5.00
53 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
54 INT2241 Negative_regulation of CEL 56 0.58 29.32 8.83 5.00
55 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58 5.00
56 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86 5.00
57 INT78226 Gene_expression of Mbp 43 0.75 22.14 7.79 5.00
58 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25 5.00
59 INT126984 Positive_regulation of Gene_expression of Il5 29 0.69 20.61 6.72 5.00
60 INT304151 Gene_expression of Siglec5 2 0.74 17.33 6.03 5.00
61 INT113101 Gene_expression of Ccl11 41 0.76 22.36 5.47 5.00
62 INT177526 Negative_regulation of Il5 17 0.36 11.13 5.31 5.00
63 INT117004 Gene_expression of Sfpi1 21 0.75 15.95 5.29 5.00
64 INT18995 Binding of CEL 23 0.47 14.46 4.5 5.00
65 INT108342 Negative_regulation of EPHB2 18 0.57 9.48 4.46 5.00
66 INT72385 Phosphorylation of Shc1 11 0.52 1.62 4.1 5.00
67 INT123752 Regulation of Bax 19 0.60 16.45 4 5.00
68 INT112692 Localization of Bax 31 0.80 20.97 3.98 5.00
69 INT4464 Localization of CEL 21 0.80 8.09 3.88 5.00
70 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75 5.00
71 INT70919 Binding of Il4 19 0.36 6.58 3.59 5.00
72 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5 5.00
73 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38 5.00
74 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16 5.00
75 INT114276 Gene_expression of Nr4a1 20 0.77 7.71 3.14 5.00
76 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16 5.00
77 INT98225 Regulation of Il5 8 0.45 5.07 2.06 5.00
78 INT20377 Gene_expression of Il3 8 0.65 0.82 1.77 5.00
79 INT91430 Positive_regulation of CD44 25 0.69 15.43 1.76 5.00
80 INT186269 Binding of Il13 9 0.39 7.7 1.64 5.00
81 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6 5.00
82 INT114279 Positive_regulation of Nr4a1 9 0.59 3.37 1.59 5.00
83 INT114270 Gene_expression of Plscr1 6 0.47 1.33 1.49 5.00
84 INT254666 Positive_regulation of Map2k2 37 0.56 23.85 1.35 5.00
85 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3 5.00
86 INT102200 Gene_expression of Nr4a2 9 0.72 3.69 1.28 5.00
87 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2 5.00
88 INT114272 Regulation of Gene_expression of Nr4a1 5 0.45 1.82 1.14 5.00
89 INT91431 Positive_regulation of Gene_expression of CD44 18 0.69 9.25 1.12 5.00
90 INT105543 Gene_expression of DNTT 11 0.65 4.63 1 5.00
91 INT117002 Negative_regulation of Sfpi1 16 0.58 9.72 1 5.00
92 INT73450 Gene_expression of Pilra 7 0.05 2.87 0.97 5.00
93 INT123948 Positive_regulation of Plscr1 4 0.42 1.02 0.93 5.00
94 INT228727 Transcription of Il5 4 0.27 5.13 0.9 5.00
95 INT160830 Gene_expression of Siglece 6 0.39 2.37 0.85 5.00
96 INT150165 Gene_expression of MTTP 21 0.75 10.1 0.73 5.00
97 INT94300 Negative_regulation of Gene_expression of Mbp 6 0.44 1.79 0.7 5.00
98 INT304148 Gene_expression of Csf2ra 1 0.36 2.09 0.65 5.00
99 INT59792 Gene_expression of STH 14 0.75 15.2 0.61 5.00
100 INT147554 Gene_expression of Birc2 11 0.75 10.93 0.6 5.00
101 INT73524 Positive_regulation of Ear1 7 0.27 4.82 0.54 5.00
102 INT163925 Localization of Epx 3 0.51 2.23 0.39 5.00
103 INT98745 Regulation of Ear1 2 0.51 0.36 0.38 5.00
104 INT181020 Positive_regulation of Gene_expression of Sfpi1 2 0.67 1.11 0.31 5.00
105 INT304143 Negative_regulation of Transcription of Il5 1 0.08 1 0.3 5.00
106 INT280707 Gene_expression of Cebpg 4 0.75 0.37 0.29 5.00
107 INT304144 Localization of Csf2ra 1 0.32 0.3 0.27 5.00
108 INT181036 Positive_regulation of Sfpi1 3 0.49 0.96 0.21 5.00
109 INT304142 Negative_regulation of Phosphorylation of Lyn 1 0.12 1.11 0.2 5.00
110 INT199771 Localization of Ahr 8 0.70 4.86 0.2 5.00
111 INT261820 Phosphorylation of Lyn 5 0.30 1.41 0.2 5.00
112 INT304145 Phosphorylation of Grb2 1 0.03 0.72 0.2 5.00
113 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09 5.00
114 INT304139 Gene_expression of Ccl26 1 0.36 1.33 0.08 5.00
115 INT304149 Positive_regulation of Transcription of Il5 1 0.09 1.81 0.08 5.00
116 INT304173 Binding of SIGLEC8 1 0.07 1.18 0.06 5.00
117 INT304136 Positive_regulation of Fip1l1 1 0.24 1.7 0.05 5.00
118 INT241509 Negative_regulation of Gene_expression of Lyn 2 0.20 1.02 0.05 5.00
119 INT275621 Positive_regulation of Atcay 3 0.06 2.15 0.04 5.00
120 INT201641 Binding of Apaf1 3 0.16 2.36 0.03 5.00
121 INT304150 Regulation of Irf8 1 0.17 0.07 0.03 5.00
122 INT304140 Regulation of Negative_regulation of Casp3 1 0.05 0.67 0 5.00
123 INT304141 Positive_regulation of Localization of Epx 1 0.22 0.72 0 5.00
124 INT159245 Gene_expression of Dut 3 0.65 0.82 0 5.00
125 INT208959 Positive_regulation of Gene_expression of Dut 1 0.49 0.7 0 5.00
126 INT304147 Gene_expression of Fip1l1 1 0.32 2.07 0 5.00
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