D:Closed Fractures

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pChart

Disease Term
Synonyms Closed Fracture, Fracture Closed, FRACTURE OCCULT, Fractures Occult, Occult Fracture, OCCULT FRACTURES
Documents 151
Hot Single Events 4
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Closed Fractures. They are ordered first by their relevance to Closed Fractures and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT278021 BMP2 Positive_regulation of Gene_expression of RUNX1T1 1 0.02 0.5 0 76.88
2 INT316598 Pth Regulation of Fgf23 1 0.10 0.28 0.03 5.00
3 INT316600 Binding of Acp5 and Matk 1 0.01 0 0 5.00
4 INT316599 Positive_regulation of Binding of Acp5 and Matk 1 0.01 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Closed Fractures. They are ordered first by their pain relevance and then by number of times they were reported in Closed Fractures. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT201967 Positive_regulation of Bmpr2 4 0.31 1.24 0.34 97.04
2 INT81982 Gene_expression of Bmpr2 36 0.60 14.58 1.55 96.84
3 INT278040 Negative_regulation of Localization of BMP2 1 0.32 0.32 0 92.16
4 INT85808 Localization of BMP2 7 0.77 1.94 0.51 91.92
5 INT39866 Gene_expression of RUNX1T1 2 0.65 1.75 0.1 76.88
6 INT105021 Binding of GOPC 187 0.40 60.39 20.38 73.16
7 INT149259 Gene_expression of RCT 38 0.67 15.73 3.87 61.60
8 INT219929 Positive_regulation of Gene_expression of Bmpr2 3 0.15 0.9 0 54.56
9 INT201962 Transcription of Bmpr2 6 0.37 3.51 0.09 41.92
10 INT133695 Transcription of Ibsp 4 0.36 5.7 1.32 33.68
11 INT176513 Transcription of Spp1 5 0.63 4.32 0.67 31.44
12 INT321617 Negative_regulation of IMAGE 1 0.01 0.44 0.12 25.28
13 INT114664 Binding of BMP2 12 0.37 6.54 0.91 22.16
14 INT316584 Gene_expression of Hopx 1 0.02 2 0 20.16
15 INT109699 Regulation of BMP2 5 0.43 2.21 0.23 15.20
16 INT2792 Gene_expression of Mb 91 0.76 41.56 10.25 13.12
17 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
18 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
19 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
20 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 5.00
21 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 5.00
22 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 5.00
23 INT171820 Localization of Fig4 144 0.65 27.38 20.88 5.00
24 INT3364 Binding of SGCG 87 0.47 31.93 17.24 5.00
25 INT170033 Positive_regulation of Gene_expression of Fig4 59 0.43 20.99 16.69 5.00
26 INT157941 Gene_expression of IL-17 65 0.65 20.39 9.89 5.00
27 INT5401 Gene_expression of DBH 17 0.78 1.92 8.01 5.00
28 INT122901 Positive_regulation of Spp1 67 0.67 58.03 7.49 5.00
29 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11 5.00
30 INT20673 Binding of CDS1 18 0.31 1.96 5.72 5.00
31 INT170604 Negative_regulation of Gene_expression of GOPC 50 0.35 12.71 4.51 5.00
32 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26 5.00
33 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05 5.00
34 INT113029 Negative_regulation of Myo5a 7 0.48 0.97 2.95 5.00
35 INT45575 Gene_expression of Ibsp 8 0.50 11.83 2.85 5.00
36 INT61465 Gene_expression of Acp5 22 0.75 7.06 2.55 5.00
37 INT157943 Positive_regulation of IL-17 10 0.58 6.65 2.43 5.00
38 INT42369 Localization of Ibsp 6 0.62 2.51 2.17 5.00
39 INT176510 Binding of Spp1 21 0.42 22.1 2 5.00
40 INT176516 Localization of Spp1 28 0.76 19.39 1.9 5.00
41 INT22785 Negative_regulation of PRNP 12 0.57 5.09 1.57 5.00
42 INT243655 Positive_regulation of Gene_expression of IL-17 11 0.58 3.06 1.45 5.00
43 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42 5.00
44 INT45576 Positive_regulation of Ibsp 4 0.41 3.41 1.21 5.00
45 INT29788 Gene_expression of DNASE1L1 3 0.03 0.61 0.99 5.00
46 INT42370 Negative_regulation of Ibsp 3 0.38 0.68 0.81 5.00
47 INT171096 Transcription of PDGFA 5 0.47 4.42 0.79 5.00
48 INT130797 Gene_expression of Fgf23 6 0.66 4.73 0.77 5.00
49 INT176528 Regulation of Spp1 9 0.45 9.05 0.77 5.00
50 INT151217 Phosphorylation of SIGMAR1 2 0.04 0.41 0.72 5.00
51 INT139205 Binding of NRP1 27 0.45 4.34 0.71 5.00
52 INT155861 Negative_regulation of ENOSF1 3 0.42 3.29 0.63 5.00
53 INT121141 Transcription of Spp1 6 0.34 5.02 0.38 5.00
54 INT251324 Binding of Bmpr2 5 0.23 2.99 0.34 5.00
55 INT157409 Negative_regulation of Fgf23 3 0.50 3.21 0.27 5.00
56 INT10425 Positive_regulation of Myo5a 5 0.66 0.41 0.21 5.00
57 INT130798 Positive_regulation of Gene_expression of Fgf23 2 0.59 1.12 0.2 5.00
58 INT135975 Binding of Ibsp 2 0.31 0.31 0.15 5.00
59 INT278037 Positive_regulation of Transcription of PDGFA 4 0.07 2.39 0.12 5.00
60 INT278036 Negative_regulation of BMP2 2 0.34 0.64 0.09 5.00
61 INT254332 Negative_regulation of Gene_expression of Bmpr2 3 0.22 2.41 0.07 5.00
62 INT316587 Gene_expression of Matk 1 0.07 1.53 0.06 5.00
63 INT316595 Transcription of Fgf23 1 0.61 0.44 0.04 5.00
64 INT316589 Negative_regulation of Transcription of Fgf23 1 0.50 0.44 0.04 5.00
65 INT278039 Phosphorylation of BMPR2 1 0.08 0.26 0.03 5.00
66 INT316576 Transcription of Acp5 1 0.11 0.79 0.03 5.00
67 INT316588 Positive_regulation of Fgf23 1 0.43 0.29 0.03 5.00
68 INT316593 Transcription of Matk 1 0.06 0.79 0.03 5.00
69 INT278034 Transcription of BMP1 1 0.07 0.25 0.03 5.00
70 INT278022 Phosphorylation of Bmpr2 1 0.21 0.27 0.03 5.00
71 INT316586 Regulation of Transcription of Ibsp 1 0.23 0.16 0 5.00
72 INT316591 Regulation of Gene_expression of Matk 1 0.04 0.06 0 5.00
73 INT316594 Negative_regulation of Binding of Ibsp 1 0.21 0.06 0 5.00
74 INT316596 Regulation of Transcription of Matk 1 0.03 0.16 0 5.00
75 INT316578 Regulation of Transcription of Spp1 1 0.09 0.16 0 5.00
76 INT316580 Binding of Acp5 1 0.06 0 0 5.00
77 INT316577 Positive_regulation of Binding of Acp5 1 0.08 0 0 5.00
78 INT316592 Negative_regulation of Binding of Matk 1 0.04 0.06 0 5.00
79 INT316597 Binding of Matk 1 0.03 0.06 0 5.00
80 INT316590 Positive_regulation of Binding of Matk 1 0.04 0 0 5.00
81 INT316579 Negative_regulation of Binding of Spp1 1 0.09 0.06 0 5.00
82 INT278035 Positive_regulation of Gene_expression of DNASE1L1 1 0.01 0.38 0 5.00
83 INT316585 Regulation of Gene_expression of Hopx 1 0.01 0.63 0 5.00
84 INT316575 Regulation of Transcription of Acp5 1 0.06 0.16 0 5.00
85 INT61467 Regulation of Gene_expression of Acp5 1 0.59 0.06 0 5.00
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