D:Clubfoot

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pChart

Disease Term
Synonyms Equinovarus, Talipes Equinovarus
Documents 133
Hot Single Events 4
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Clubfoot. They are ordered first by their relevance to Clubfoot and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT265964 TNNI2 Regulation of CA2 1 0.22 0.09 0 5.00
2 INT287088 Binding of EEC1 and Vamp3 1 0.09 1.02 0 5.00
3 INT192618 Atrx Regulation of Gene_expression of Hba-a1 1 0.08 0.45 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Clubfoot. They are ordered first by their pain relevance and then by number of times they were reported in Clubfoot. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05 87.24
2 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16 81.20
3 INT1030 Localization of Lbp 52 0.74 38.92 24.91 81.20
4 INT1029 Positive_regulation of Gene_expression of Lbp 17 0.50 11.03 5.18 81.20
5 INT961 Positive_regulation of ATRX 3 0.53 1.99 0.36 79.44
6 INT287082 Gene_expression of Vamp3 1 0.18 0.99 0.11 72.64
7 INT22502 Gene_expression of Hal 21 0.53 9.8 3.32 63.20
8 INT144689 Regulation of RCT 49 0.53 25.91 9.6 25.00
9 INT59680 Binding of Lynx1 10 0.12 1.53 2.19 25.00
10 INT40578 Gene_expression of Lynx1 4 0.04 0.66 0.71 25.00
11 INT265971 Gene_expression of MYH3 1 0.66 1.2 0 16.68
12 INT265967 Gene_expression of TNNI2 1 0.67 1.39 0 16.68
13 INT265968 Gene_expression of TNNT3 1 0.65 1.39 0 16.68
14 INT265970 Binding of TNNI2 1 0.37 0.2 0 15.40
15 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 6.16
16 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 5.00
17 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 5.00
18 INT626 Localization of CALCA 289 0.81 125.39 221.15 5.00
19 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
20 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34 5.00
21 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 5.00
22 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23 5.00
23 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 5.00
24 INT65730 Gene_expression of Cnr2 129 0.78 60.15 63.1 5.00
25 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 5.00
26 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75 5.00
27 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
28 INT63383 Binding of Cnr1 77 0.48 22.28 44.61 5.00
29 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8 5.00
30 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 5.00
31 INT101578 Regulation of Cnr2 26 0.62 16.7 19.12 5.00
32 INT120446 Positive_regulation of Cnr2 32 0.70 16.3 18.91 5.00
33 INT66004 Binding of Cnr2 35 0.48 12.82 18.63 5.00
34 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 5.00
35 INT20721 Localization of ACOT1 47 0.80 11.37 10.95 5.00
36 INT94465 Positive_regulation of Gene_expression of Hand1 43 0.38 29.76 10.88 5.00
37 INT25585 Positive_regulation of DNAH8 39 0.70 17.96 7.85 5.00
38 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01 5.00
39 INT106189 Regulation of Il12a 18 0.44 12.4 5.3 5.00
40 INT46350 Gene_expression of Msr1 32 0.65 29.39 4.55 5.00
41 INT30031 Gene_expression of Hba-a1 7 0.60 7.46 4.41 5.00
42 INT111099 Positive_regulation of Dusp1 11 0.68 7.62 3.18 5.00
43 INT6895 Localization of Mastl 5 0.31 2.94 2.96 5.00
44 INT114295 Gene_expression of Gli2 10 0.54 7.58 2.95 5.00
45 INT20722 Regulation of Localization of ACOT1 5 0.27 1.43 2.86 5.00
46 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68 5.00
47 INT20720 Negative_regulation of Localization of ACOT1 6 0.35 2.66 2.25 5.00
48 INT47543 Positive_regulation of Chrm3 11 0.38 5.23 2.17 5.00
49 INT70987 Binding of RAC1 14 0.37 12.14 2.13 5.00
50 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02 5.00
51 INT258780 Regulation of Il23a 6 0.13 4.77 1.96 5.00
52 INT258781 Regulation of Regulation of Il12a 1 0.17 1.54 1.87 5.00
53 INT115303 Localization of SNAP25 8 0.73 1.43 1.82 5.00
54 INT140245 Binding of Gli3 3 0.36 2.65 1.46 5.00
55 INT58930 Negative_regulation of RAC1 14 0.55 7.55 1.4 5.00
56 INT252325 Gene_expression of Ahi1 4 0.04 4.81 1.35 5.00
57 INT81768 Negative_regulation of Chrna4 5 0.42 1.97 1.2 5.00
58 INT134822 Gene_expression of Gja1 18 0.72 4.2 1 5.00
59 INT258782 Regulation of Regulation of Il23a 1 0.13 0.77 0.92 5.00
60 INT959 Regulation of ATRX 5 0.47 5.04 0.89 5.00
61 INT258784 Negative_regulation of Gene_expression of Ahi1 1 0.02 0.9 0.83 5.00
62 INT258783 Positive_regulation of Gene_expression of Ahi1 1 0.04 0.84 0.81 5.00
63 INT287087 Localization of EEC1 2 0.61 1.6 0.72 5.00
64 INT194981 Regulation of IMPACT 5 0.38 1.47 0.63 5.00
65 INT196247 Negative_regulation of Localization of SNAP25 2 0.29 0.76 0.37 5.00
66 INT200806 Binding of EEC1 6 0.39 4.24 0.29 5.00
67 INT962 Gene_expression of ATRX 2 0.59 1.72 0.27 5.00
68 INT180599 Gene_expression of EEC1 5 0.63 2.73 0.23 5.00
69 INT320805 Gene_expression of SLC26A2 1 0.57 1.1 0.19 5.00
70 INT320806 Binding of SLC26A2 1 0.32 1.06 0.19 5.00
71 INT317881 Transcription of Eef1a1 2 0.03 1.38 0.18 5.00
72 INT282160 Regulation of Binding of RAC1 1 0.18 0.45 0.13 5.00
73 INT196691 Positive_regulation of Positive_regulation of DNAH8 2 0.10 1.23 0.13 5.00
74 INT114110 Negative_regulation of EEC1 2 0.37 2.35 0.12 5.00
75 INT265969 Regulation of TNNI2 1 0.45 1.35 0.09 5.00
76 INT265966 Regulation of MYH3 1 0.44 1.35 0.09 5.00
77 INT329075 Transcription of MYT1 1 0.27 0.37 0.08 5.00
78 INT329073 Regulation of Myt1 1 0.42 0.34 0.08 5.00
79 INT329074 Transcription of Pcmtd2 1 0.66 0.37 0.08 5.00
80 INT320807 Positive_regulation of SLC26A2 1 0.59 0.46 0.07 5.00
81 INT287085 Negative_regulation of Myh9 1 0.21 0.6 0.03 5.00
82 INT329071 Negative_regulation of Arfgap1 1 0.41 1.14 0.03 5.00
83 INT329072 Negative_regulation of Kcnq2 1 0.42 1.14 0.03 5.00
84 INT287083 Binding of Vamp3 1 0.14 1.58 0 5.00
85 INT192611 Negative_regulation of Gene_expression of Hba-a1 1 0.07 0.86 0 5.00
86 INT192615 Localization of Atrx 1 0.74 0.1 0 5.00
87 INT192609 Negative_regulation of Gene_expression of Atrx 1 0.37 0.28 0 5.00
88 INT192616 Negative_regulation of Atrx 1 0.43 1.04 0 5.00
89 INT192608 Regulation of Atrx 1 0.39 0.67 0 5.00
90 INT265972 Positive_regulation of Gene_expression of ATRX 1 0.38 1.72 0 5.00
91 INT322199 Binding of AMCN 6 0.42 3 0 5.00
92 INT287084 Regulation of Vamp3 1 0.12 0.71 0 5.00
93 INT192610 Positive_regulation of Atrx 1 0.50 0.78 0 5.00
94 INT192613 Positive_regulation of Binding of Atrx 1 0.69 0.09 0 5.00
95 INT192619 Regulation of SMARCA2 1 0.06 0.3 0 5.00
96 INT192617 Binding of Atrx 1 0.48 0.58 0 5.00
97 INT183821 Gene_expression of AMCN 5 0.65 1.89 0 5.00
98 INT192620 Regulation of BTAF1 1 0.06 0.3 0 5.00
99 INT192612 Regulation of Gene_expression of Hba-a1 1 0.07 0.99 0 5.00
100 INT287086 Regulation of Gene_expression of EEC1 1 0.36 0.42 0 5.00
101 INT192614 Gene_expression of Atrx 1 0.77 1.75 0 5.00
102 INT192607 Transcription of Atrx 1 0.68 0.4 0 5.00
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