D:Colon Cancer

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Disease Term
Synonyms ADENOCARCINOMAS OF THE COLON, Cancer Colon, CANCER COLONIC, Cancer Of Colon, Cancer Of The Colon, Cancers Colon, CANCERS COLONIC, COLON ADENOCARCINOMA, COLON CANCERS, Colon Carcinoma, COLON CARCINOMAS
Documents 3800
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Colon Cancer. They are ordered first by their relevance to Colon Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT307804 Ace Positive_regulation of Gene_expression of Scrib 1 0.21 2.43 0 100.00
2 INT307808 Ace Positive_regulation of Gene_expression of Ace2 1 0.22 2.43 0 100.00
3 INT326162 Binding of ABHD2 and Scrib 1 0.00 1.07 0 100.00
4 INT326165 Binding of ABHD12 and Scrib 1 0.00 1.01 0 100.00
5 INT350433 KRAS Regulation of Gene_expression of BRAF 1 0.08 1.77 0 100.00
6 INT253328 Binding of IL8 and Scrib 1 0.04 0.79 0.12 100.00
7 INT333251 Binding of Bcl2l11 and Cxcl12 1 0.14 1.74 0.08 100.00
8 INT87710 MYB Regulation of PTGS2 1 0.28 0.64 0.15 100.00
9 INT126887 Protein_catabolism of SP4 Negative_regulation of Gene_expression of VEGFA 1 0.15 0.49 0.26 100.00
10 INT126886 Protein_catabolism of SP1 Negative_regulation of Gene_expression of VEGFA 1 0.03 0.49 0.26 100.00
11 INT333253 Binding of Bcl2 and Mcl1 1 0.02 2.14 0.04 100.00
12 INT140771 Binding of NTN4 and Unc5a 1 0.02 0.35 0.07 100.00
13 INT140770 Binding of NTN4 and Unc5a 1 0.01 0.35 0.07 100.00
14 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89 100.00
15 INT333252 Positive_regulation of Binding of Bcl2 and Mcl1 1 0.03 0.88 0.04 100.00
16 INT333254 Binding of Mcl1 and Cxcl12 1 0.10 0.88 0.04 100.00
17 INT333244 Positive_regulation of Binding of Mcl1 and Cxcl12 1 0.13 0.88 0.04 100.00
18 INT333245 Binding of Bcl2 and Bcl2l11 1 0.03 0.87 0.04 100.00
19 INT351157 TSC1 Positive_regulation of Gene_expression of CAV1 1 0.01 1.43 0 100.00
20 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27 100.00
21 INT220527 Nme1 Negative_regulation of Positive_regulation of Vegfa 1 0.00 1.23 0.12 100.00
22 INT241268 DNMT3B Positive_regulation of Gene_expression of DNMT1 1 0.19 0.67 0 100.00
23 INT263900 Binding of Col1a1 and Cea 1 0.01 0.63 0 100.00
24 INT241266 DNMT3B Positive_regulation of Gene_expression of GOPC 1 0.05 0.68 0 100.00
25 INT232595 Binding of BRCA1 and HEPACAM 1 0.02 0.89 0 100.00
26 INT241264 DNMT1 Positive_regulation of Gene_expression of DNMT3B 1 0.19 0.67 0 100.00
27 INT241257 DNMT3B Positive_regulation of OPCML 1 0.35 0.68 0 100.00
28 INT241259 DNMT3B Positive_regulation of GOPC 1 0.05 0.68 0 100.00
29 INT241265 DNMT1 Positive_regulation of OPCML 1 0.31 0.68 0 100.00
30 INT241269 DNMT1 Positive_regulation of Gene_expression of GOPC 1 0.04 0.68 0 100.00
31 INT326164 Binding of S100A2 and Scrib 1 0.01 1.16 0 100.00
32 INT241254 DNMT1 Positive_regulation of GOPC 1 0.04 0.68 0 100.00
33 INT102505 VEGFA Negative_regulation of Fdft1 1 0.00 0.56 0.06 99.92
34 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58 99.92
35 INT257989 PTGER2 Positive_regulation of RASGRP1 1 0.01 0.61 0.21 99.84
36 INT257985 PTGER2 Positive_regulation of MAPK1 1 0.04 0.61 0.2 99.84
37 INT350429 Negative_regulation of MAPK14 Regulation of Gene_expression of ATF3 1 0.12 0.78 0 99.84
38 INT135947 MCC Regulation of GDF15 1 0.11 1.58 0.27 99.84
39 INT351770 Binding of Il6 and Ikbkb 1 0.10 1.06 0.29 99.84
40 INT257976 Positive_regulation of EGFR Positive_regulation of PTGER2 Positive_regulation of RASGRP1 1 0.00 0.31 0.11 99.84
41 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37 99.84
42 INT234625 TP53 Positive_regulation of IGFBP3 1 0.29 0.74 0.03 99.84
43 INT269209 SNAI1 Regulation of Gene_expression of LOXL2 1 0.07 1.14 0 99.84
44 INT350426 Binding of BRAF and KRAS 1 0.05 1.78 0 99.78
45 INT117913 CREM Positive_regulation of Negative_regulation of BIRC2 1 0.15 0.81 0.14 99.78
46 INT80030 Binding of FAS and TNF 3 0.27 2.54 0.56 99.72
47 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8 99.68
48 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45 99.68
49 INT199370 DST Regulation of Gene_expression of Igf2 1 0.02 1.07 0 99.60
50 INT220530 Atf3 Positive_regulation of Gene_expression of Gdf15 1 0.03 1.08 0.18 99.60
51 INT333246 Binding of Cxcr4 and Cxcl12 3 0.34 0.99 0.27 99.48
52 INT254704 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK1 1 0.10 1.43 0 99.44
53 INT254706 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0 99.44
54 INT254703 Map2k1 Positive_regulation of Phosphorylation of MAPK1 1 0.10 0.91 0 99.44
55 INT254702 Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0 99.44
56 INT254708 Map2k2 Positive_regulation of Phosphorylation of MAPK1 1 0.11 0.86 0 99.44
57 INT254705 Map2k2 Positive_regulation of Phosphorylation of MAPK3 1 0.08 0.86 0 99.44
58 INT145014 Positive_regulation of GAST Positive_regulation of PTGS2 1 0.31 0.51 0.22 99.40
59 INT145012 GAST Positive_regulation of PTGS2 1 0.42 0.51 0.22 99.40
60 INT145015 CREB5 Positive_regulation of GAST Positive_regulation of PTGS2 1 0.06 0.51 0.22 99.40
61 INT92581 IGF1R Positive_regulation of Gene_expression of PTGER2 1 0.09 0.79 0.24 99.32
62 INT92580 IGF2 Positive_regulation of Gene_expression of PTGER2 1 0.07 0.43 0.15 99.32
63 INT147358 Egr1 Positive_regulation of Gene_expression of Gdf15 1 0.14 1.56 0.28 99.24
64 INT320880 Chi3l1 Positive_regulation of Agtr2 1 0.01 1.22 0.08 99.24
65 INT301126 Tgm7 Regulation of Localization of Mmp2 1 0.38 0.2 0.03 99.24
66 INT108329 EGF Positive_regulation of Phosphorylation of EPHB2 4 0.48 3.96 0.48 99.20
67 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9 99.20
68 INT245078 FGF2 Positive_regulation of CXCR4 1 0.07 1.36 0 99.20
69 INT136540 Binding of CYP2C9 and Ugt1a6a 1 0.27 0.81 0.86 99.12
70 INT333255 Cxcl12 Regulation of Mcl1 1 0.12 1.12 0.15 99.04
71 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28 99.04
72 INT147356 Egr1 Positive_regulation of Gene_expression of Btg1 1 0.14 1.56 0.28 99.00
73 INT134400 Positive_regulation of PRKG1 Positive_regulation of Phosphorylation of MAPK8 1 0.30 1.13 0.14 98.96
74 INT285688 Cpox Positive_regulation of PPARA 1 0.02 1 0.5 98.96
75 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23 98.94
76 INT92583 IGF2 Positive_regulation of Transcription of PTGER2 1 0.07 0.43 0.15 98.92
77 INT92582 IGF1R Positive_regulation of Transcription of PTGER2 1 0.09 0.43 0.15 98.92
78 INT315060 PAR4 Regulation of BCL2 1 0.53 0.48 0 98.88
79 INT350430 Negative_regulation of HSP90AA1 Positive_regulation of ATF3 1 0.32 3.11 0 98.84
80 INT228055 WNT1 Positive_regulation of CTNND2 1 0.54 1.75 0.42 98.80
81 INT348595 Binding of PPARG and ZACN 1 0.07 0.38 0 98.76
82 INT163614 POMC Regulation of MME 1 0.08 0.39 0 98.72
83 INT283859 Binding of ACTN4 and TREH 1 0.00 1.61 0 98.68
84 INT289101 Binding of KCNA1 and LEF1 1 0.00 2.58 0.03 98.68
85 INT333241 Cxcl12 Regulation of Bcl2l11 1 0.18 1.11 0.15 98.64
86 INT333250 Binding of Cxcr7 and Cxcl12 1 0.19 1.39 0.18 98.56
87 INT350431 HSP90AA1 Positive_regulation of ATF3 1 0.47 1.55 0 98.48
88 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06 98.48
89 INT302147 PTGER2 Positive_regulation of BAK1 1 0.06 2.08 0.06 98.48
90 INT302138 PTGER2 Positive_regulation of Gene_expression of BAK1 1 0.06 2.08 0.06 98.48
91 INT337639 TP53 Regulation of Gene_expression of MIR34A 1 0.08 1.19 0 98.44
92 INT304186 Ang Positive_regulation of Gene_expression of VEGFA 2 0.05 2.5 0.06 98.36
93 INT269210 CDH1 Positive_regulation of Positive_regulation of ITK 1 0.06 0.84 0.06 98.36
94 INT135941 Positive_regulation of PDE2A Positive_regulation of Gene_expression of PRKG1 1 0.13 0.8 0.13 98.36
95 INT139044 AKR1B1 Regulation of Gene_expression of PTGS2 1 0.09 0.37 0.3 98.32
96 INT186097 EGF Positive_regulation of Positive_regulation of EGFR 1 0.20 0.38 0.04 98.32
97 INT324605 Binding of CEACAM7 and SNCG 1 0.39 4.68 0 98.24
98 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67 98.24
99 INT350434 Negative_regulation of HSP90AA1 Positive_regulation of Gene_expression of ATF3 1 0.32 2.44 0.04 98.20
100 INT25400 Binding of Ptger1 and Ptger2 2 0.11 1.02 0.15 98.16
101 INT282288 Binding of Hmgcr and Nos2 1 0.03 1.99 0 98.10
102 INT282287 Binding of Cpox and Hmgcr 1 0.01 0.99 0 98.10
103 INT262750 GLYR1 Positive_regulation of THBS1 1 0.01 0.99 0 97.80
104 INT159527 Binding of GDF15 and SLC17A5 1 0.14 1.15 0.51 97.72
105 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18 97.68
106 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22 97.68
107 INT326128 Binding of CXCL3 and CXCL6 1 0.06 1.18 0.05 97.64
108 INT326127 Binding of CXCL3 and CXCR1 1 0.13 1.16 0.05 97.64
109 INT326125 Binding of CXCL3 and IL1RAPL1 1 0.01 1.16 0.05 97.64
110 INT277927 WIF1 Negative_regulation of SMAD4 1 0.23 0.37 0 97.64
111 INT277928 WIF1 Negative_regulation of TLE1 1 0.26 0.37 0 97.64
112 INT282285 Cpox Regulation of Gene_expression of Ptger2 1 0.00 0.84 0.5 97.56
113 INT87294 SERPINA3 Negative_regulation of PTGS2 1 0.25 0.6 0.58 97.52
114 INT166953 LYRM4 Positive_regulation of Gene_expression of GDF15 1 0.10 1.6 0.51 97.48
115 INT240435 JUN Positive_regulation of Gene_expression of CPOX 1 0.01 0.81 0.18 97.44
116 INT5645 Sult2a1 Positive_regulation of Positive_regulation of IGKV2-29 1 0.00 0.39 0.22 97.36
117 INT5646 Sult2a1 Positive_regulation of IGKV2-29 1 0.00 0.39 0.22 97.36
118 INT121581 Negative_regulation of PIK3CG Positive_regulation of GDF15 1 0.36 0.59 0.24 97.36
119 INT193214 Binding of PTGER2 and PTGER4 2 0.08 2.51 0.18 97.32
120 INT307814 Ace Positive_regulation of Ace Positive_regulation of Ang 1 0.30 3.05 0.15 97.12
121 INT307813 Ace Positive_regulation of Ace Positive_regulation of Agt 1 0.27 3.05 0.15 97.12
122 INT307807 Ace Positive_regulation of ras 1 0.38 3 0.15 97.12
123 INT346838 ZNF434 Regulation of PTGS2 1 0.01 0.34 0 97.12
124 INT346836 MECP2 Regulation of PTGS2 1 0.00 0.34 0 97.12
125 INT346837 ZNF434 Regulation of MECP2 1 0.00 0.34 0 97.12
126 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 97.08
127 INT206705 Negative_regulation of Binding of FLT1 and VEGFA 3 0.11 1.9 0 97.08
128 INT277136 Ebp Positive_regulation of Gene_expression of Mlh1 1 0.01 1.45 0 97.08
129 INT337637 SIRT1 Negative_regulation of TP53 1 0.23 1.49 0 96.86
130 INT114067 Ace Regulation of Insr 1 0.09 0.31 0.39 96.80
131 INT107392 PTGS2 Positive_regulation of PTGS1 2 0.31 1.01 0.26 96.76
132 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 96.72
133 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 96.72
134 INT134401 Negative_regulation of MAPK3 Negative_regulation of Gene_expression of ARMC3 1 0.19 1.16 0.13 96.60
135 INT134399 Negative_regulation of MAPK3 Positive_regulation of Phosphorylation of MAPK8 1 0.39 1.14 0.13 96.60
136 INT58588 IFNG Positive_regulation of ARHGAP4 1 0.31 1.22 0.19 96.32
137 INT287891 Binding of CDH1 and KRT20 1 0.00 0.5 0 96.32
138 INT177793 EGR1 Positive_regulation of Negative_regulation of TP53 1 0.18 0.44 0 96.04
139 INT258289 Hmgb1 Positive_regulation of Tlr2 4 0.48 3.61 0.19 95.96
140 INT351771 Il6 Positive_regulation of Localization of Crp 1 0.01 0.94 0.48 95.92
141 INT334423 Binding of SPINK1 and Cea 1 0.02 2.53 0.17 95.84
142 INT307805 Ace Positive_regulation of Ang 1 0.32 1.52 0.07 95.80
143 INT307806 Ace Positive_regulation of Agt 1 0.28 1.51 0.07 95.80
144 INT235430 Il13 Positive_regulation of Gene_expression of Olr1 1 0.00 2.12 0.33 95.64
145 INT177786 TFAM Regulation of Gene_expression of MT1F 1 0.00 0.17 0 95.52
146 INT173199 CNOT4 Regulation of Regulation of Myc 1 0.01 0.66 0.03 95.40
147 INT315064 Binding of RELA and PAR4 1 0.08 0.45 0 95.28
148 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25 95.24
149 INT314055 THL Negative_regulation of Localization of VEGFA 1 0.04 3.73 0.11 95.12
150 INT304014 Binding of MSI1 and SGCG 1 0.00 1.92 0 95.08
151 INT354925 ALB Positive_regulation of ALPP 1 0.34 1.69 0.09 94.92
152 INT139047 Negative_regulation of AR Negative_regulation of Positive_regulation of CPOX 1 0.07 0.76 0.4 94.84
153 INT139046 Negative_regulation of AR Negative_regulation of Phosphorylation of DYT10 1 0.33 0.34 0.23 94.84
154 INT139050 Negative_regulation of AR Negative_regulation of Phosphorylation of PRKCB 1 0.02 0.34 0.23 94.84
155 INT139045 Negative_regulation of AR Negative_regulation of CPOX 1 0.07 0.34 0.23 94.84
156 INT139048 Negative_regulation of AR Negative_regulation of Positive_regulation of TRAF3IP2 1 0.02 0.34 0.23 94.84
157 INT139049 Negative_regulation of AR Negative_regulation of Positive_regulation of DYT10 1 0.33 0.34 0.23 94.84
158 INT147359 Positive_regulation of Pik3cd Positive_regulation of Egr1 1 0.09 1.51 0.27 94.68
159 INT147360 Pik3cd Positive_regulation of Egr1 1 0.12 1.51 0.27 94.68
160 INT262208 Clta Positive_regulation of Nr1i2 1 0.09 0.59 0.29 94.52
161 INT257986 Binding of PTGER2 and GOPC 1 0.04 0.42 0.16 94.44
162 INT236720 Binding of Ctnnd2 and Tcf4 3 0.24 2.8 0 94.40
163 INT196348 PTGER2 Negative_regulation of Negative_regulation of MMP2 1 0.01 0.29 0.43 94.40
164 INT308352 Binding of Ctnnd2 and Tcf7l2 1 0.15 0.74 0 94.40
165 INT300337 Gene_expression of MITF Negative_regulation of Gene_expression of TSC1 1 0.00 0.65 0 94.40
166 INT314042 THL Negative_regulation of Gene_expression of Mmp2 1 0.19 2.97 0.42 94.32
167 INT314049 THL Negative_regulation of Gene_expression of Plau 1 0.20 2.91 0.19 94.32
168 INT314041 THL Negative_regulation of Gene_expression of Mmp9 1 0.13 1.86 0.14 94.32
169 INT258005 Binding of PTGER3 and Prkaca 1 0.03 0.52 0.04 94.28
170 INT177794 BUB1B Positive_regulation of Gene_expression of ASNS 1 0.11 0.77 0.46 94.24
171 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26 94.12
172 INT84885 APC Regulation of APC Regulation of PPARD 1 0.18 0.55 0.41 94.12
173 INT265546 Gla Regulation of C6 1 0.01 0.98 0 93.92
174 INT330484 Binding of Cxadr and Hspg2 1 0.18 0.52 0.03 93.88
175 INT147357 Mapk9 Positive_regulation of Htr5a 1 0.06 0.76 0.12 93.80
176 INT147362 Mapk9 Positive_regulation of Ddit3 1 0.57 0.76 0.12 93.80
177 INT147361 Mapk9 Positive_regulation of Tnfrsf10b 1 0.40 0.76 0.12 93.80
178 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89 93.80
179 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17 93.76
180 INT217784 Binding of MITF and TSC1 1 0.00 1.21 0 93.72
181 INT217781 Binding of MITF and TP53 1 0.00 1.2 0 93.72
182 INT177784 PDCD2 Positive_regulation of ASNS 1 0.04 0.76 0.46 93.68
183 INT177780 BUB1B Positive_regulation of ASNS 1 0.05 0.76 0.46 93.68
184 INT113218 TNFRSF25 Positive_regulation of Localization of CYCS 1 0.18 0.74 0.07 93.68
185 INT314038 THL Negative_regulation of Pik3r1 1 0.14 0.78 0.18 93.68
186 INT333248 Bcl2l11 Regulation of Gene_expression of Cxcl12 1 0.11 0.52 0 93.68
187 INT213903 Binding of EGFR and ERBB2 10 0.37 5.03 0.04 93.56
188 INT326899 Tcf4 Positive_regulation of PLD2 1 0.28 0.49 0 93.52
189 INT326897 Tcf4 Positive_regulation of Gene_expression of PLD2 1 0.26 0.41 0 93.52
190 INT193218 Binding of PTGER1 and PTGER2 3 0.12 2.31 0.66 93.48
191 INT177791 PDCD2 Positive_regulation of ATF4 1 0.06 0.76 0.46 93.44
192 INT177781 BUB1B Positive_regulation of ATF4 1 0.07 0.76 0.46 93.44
193 INT341856 Binding of EGFR and IgG1 1 0.27 1.12 0 93.44
194 INT257988 PTGER2 Regulation of Gene_expression of PTGER1 1 0.15 0.4 0.05 93.28
195 INT177782 PDCD2 Positive_regulation of MTHFD2 1 0.06 0.76 0.46 93.08
196 INT177787 BUB1B Positive_regulation of MTHFD2 1 0.15 0.76 0.46 93.08
197 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04 92.96
198 INT348586 RSPH1 Positive_regulation of Gene_expression of PPARG 1 0.02 0.23 0 92.84
199 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57 92.68
200 INT276337 Timp1 Positive_regulation of Il10 1 0.01 0.76 0.05 92.68

Single Events

The table below shows the top 200 pain related interactions that have been reported for Colon Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Colon Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 100.00
2 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 100.00
3 INT74695 Gene_expression of Ace 41 0.73 53.33 2.33 100.00
4 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 100.00
5 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 100.00
6 INT103094 Binding of PPARA 308 0.47 177.26 34.75 100.00
7 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81 100.00
8 INT190031 Binding of Scrib 19 0.36 21.9 1.01 100.00
9 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 100.00
10 INT108325 Gene_expression of Scrib 26 0.39 48.33 1.39 100.00
11 INT145328 Negative_regulation of Scrib 25 0.16 26.79 2.66 100.00
12 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 100.00
13 INT50673 Positive_regulation of Gene_expression of CPOX 156 0.54 97.31 37.03 100.00
14 INT115805 Gene_expression of PLD2 7 0.76 12.49 4.51 100.00
15 INT315090 Positive_regulation of Gene_expression of PAR4 1 0.68 19.87 0.11 100.00
16 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 100.00
17 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 100.00
18 INT267844 Positive_regulation of Gene_expression of Ace 10 0.57 15.35 0.35 100.00
19 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 100.00
20 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48 100.00
21 INT107619 Gene_expression of PTGER3 42 0.75 15 5.61 100.00
22 INT214067 Regulation of Scrib 11 0.20 12.48 0.45 100.00
23 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11 100.00
24 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 100.00
25 INT138980 Binding of PITX2 15 0.47 10.34 0.88 100.00
26 INT79691 Regulation of Gene_expression of PPARG 10 0.50 10.44 1.62 100.00
27 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 100.00
28 INT256004 Negative_regulation of Gene_expression of Agt 2 0.34 8.07 0.13 100.00
29 INT298415 Regulation of Gene_expression of ATF3 2 0.61 7.78 0.11 100.00
30 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 100.00
31 INT50490 Regulation of PTGS2 80 0.48 39.51 25.85 100.00
32 INT50671 Regulation of Gene_expression of CPOX 45 0.54 30.99 13.83 100.00
33 INT37896 Positive_regulation of Gene_expression of PTGS1 37 0.67 17.28 9.27 100.00
34 INT267829 Regulation of Gene_expression of Scrib 2 0.20 5.89 0.19 100.00
35 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 100.00
36 INT92139 Binding of MLH1 12 0.42 15.62 1 100.00
37 INT57062 Regulation of APC 24 0.58 14.3 0.7 100.00
38 INT123536 Positive_regulation of MTHFR 7 0.57 4.74 1 100.00
39 INT281624 Gene_expression of Tag 2 0.58 8 2.4 100.00
40 INT256008 Regulation of Gene_expression of Agt 4 0.36 5.03 0.11 100.00
41 INT6481 Binding of TNF 624 0.48 510.2 214.82 100.00
42 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91 100.00
43 INT234675 Binding of SNCG 1 0.47 4.99 0 100.00
44 INT190017 Localization of Scrib 6 0.10 7 0.38 100.00
45 INT108326 Positive_regulation of Gene_expression of Scrib 5 0.26 9.02 0.36 100.00
46 INT70666 Positive_regulation of CLU 16 0.45 12.95 0.74 100.00
47 INT98708 Binding of KRAS 13 0.47 7.47 0.39 100.00
48 INT135319 Positive_regulation of Positive_regulation of CRP 20 0.50 26.45 5.61 100.00
49 INT185015 Positive_regulation of HGS 8 0.40 4.65 0.03 100.00
50 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 100.00
51 INT231987 Gene_expression of Tsp1 66 0.67 62.58 1.78 100.00
52 INT35486 Regulation of PTGER2 39 0.36 19.03 6.75 100.00
53 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 100.00
54 INT307791 Negative_regulation of Gene_expression of Scrib 1 0.19 2.55 0 100.00
55 INT124373 Positive_regulation of Gene_expression of Wnt2 14 0.42 8.28 0.6 100.00
56 INT69321 Regulation of Gene_expression of PTGS2 27 0.61 13.27 9.53 100.00
57 INT145221 Binding of Tp53 10 0.37 8.59 1.37 100.00
58 INT39256 Localization of PTGS1 17 0.74 6.62 5.1 100.00
59 INT100142 Negative_regulation of Localization of PTGS1 2 0.35 1.71 0.91 100.00
60 INT11160 Regulation of Gene_expression of EGFR 27 0.62 22.05 0.96 100.00
61 INT60346 Positive_regulation of Gene_expression of Hras 4 0.42 1.56 0.4 100.00
62 INT69992 Negative_regulation of Hmox2 93 0.50 49.01 44.07 100.00
63 INT208551 Gene_expression of Mutyh 6 0.48 6.28 0.12 100.00
64 INT267831 Negative_regulation of Positive_regulation of Scrib 1 0.04 1.56 0.31 100.00
65 INT50948 Gene_expression of SLC12A2 6 0.59 4.55 0.22 100.00
66 INT320466 Negative_regulation of Binding of Eras 1 0.18 0.53 0 100.00
67 INT163278 Regulation of Gene_expression of CAV1 5 0.45 4.36 0.14 100.00
68 INT78913 Positive_regulation of Gene_expression of ABCC1 22 0.67 5.95 5.82 100.00
69 INT100890 Positive_regulation of Gene_expression of ABCC3 5 0.68 2.12 1.41 100.00
70 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 100.00
71 INT132026 Gene_expression of Ntn1 7 0.78 5.97 6.01 100.00
72 INT283514 Localization of NR1I2 2 0.74 3.15 0.87 100.00
73 INT285812 Localization of NR1H2 2 0.50 0.95 0.41 100.00
74 INT175526 Phosphorylation of Gopc 73 0.53 21.08 7.86 100.00
75 INT75918 Negative_regulation of Negative_regulation of Cpox 19 0.23 10.05 14.4 100.00
76 INT106667 Gene_expression of NDRG1 18 0.70 9.96 5.14 100.00
77 INT15610 Localization of GOPC 223 0.65 68.26 28.7 100.00
78 INT253323 Negative_regulation of Binding of Scrib 1 0.05 0.82 0.09 100.00
79 INT134639 Regulation of DCC 1 0.01 0.64 0 100.00
80 INT217161 Regulation of MIR183 1 0.32 0.96 0.03 100.00
81 INT134796 Positive_regulation of Epdr1 1 0.06 0.68 0.1 100.00
82 INT217158 Regulation of MIR145 2 0.32 1.15 0.03 100.00
83 INT114787 Negative_regulation of Negative_regulation of Hmox2 1 0.01 0.93 1.6 100.00
84 INT217227 Regulation of MIR135B 1 0.19 0.96 0.03 100.00
85 INT217174 Regulation of MIR133B 2 0.21 1.68 0.05 100.00
86 INT69991 Negative_regulation of Gene_expression of Hmox2 3 0.04 2.05 2.51 100.00
87 INT217204 Regulation of MIR96 2 0.29 1.25 0 100.00
88 INT217229 Regulation of MIR31 1 0.29 0.95 0 100.00
89 INT267830 Regulation of Negative_regulation of Scrib 1 0.04 0.95 0.19 100.00
90 INT140767 Binding of Unc5a 1 0.05 0.38 0.05 100.00
91 INT116150 Positive_regulation of Ddit3 26 0.67 22.58 5.01 100.00
92 INT140752 Binding of DCC 1 0.36 0.38 0.05 100.00
93 INT175424 Regulation of Transcription of TSC1 2 0.05 1.39 0 100.00
94 INT217802 Regulation of Transcription of TP53 2 0.37 0.81 0.03 100.00
95 INT328041 Gene_expression of Lias 1 0.37 2.15 0.37 100.00
96 INT113219 Binding of TNFRSF25 12 0.35 9.77 0.46 100.00
97 INT253320 Positive_regulation of Positive_regulation of Scrib 1 0.05 0.4 0.14 100.00
98 INT235422 Negative_regulation of Gene_expression of cla 1 0.11 0.52 0.03 100.00
99 INT140756 Positive_regulation of NTN1 1 0.01 0.31 0 100.00
100 INT140755 Positive_regulation of DCC 1 0.49 0.31 0 100.00
101 INT21611 Negative_regulation of RASGRP1 20 0.35 11.76 2.15 100.00
102 INT234451 Positive_regulation of Phosphorylation of NR1H4 1 0.22 5.15 0 100.00
103 INT140737 Binding of Unc5a 1 0.03 0.35 0.06 100.00
104 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36 100.00
105 INT29836 Regulation of MTHFS 6 0.33 1.43 1.67 100.00
106 INT59078 Positive_regulation of Transcription of PTGS2 5 0.69 2.36 1.17 100.00
107 INT178494 Gene_expression of Angpt1 10 0.37 9.77 1.28 100.00
108 INT47706 Negative_regulation of Positive_regulation of Egr1 9 0.41 6.11 5.1 100.00
109 INT860 Regulation of ALB 48 0.60 25.11 8.95 100.00
110 INT2241 Negative_regulation of CEL 56 0.58 29.32 8.83 100.00
111 INT283019 Positive_regulation of Gene_expression of Eif5a 1 0.32 2.27 0 100.00
112 INT171820 Localization of Fig4 144 0.65 27.38 20.88 100.00
113 INT102034 Positive_regulation of Ppard 10 0.69 3.97 3.17 100.00
114 INT100728 Positive_regulation of SEMA6A 7 0.67 2.73 3.25 100.00
115 INT128889 Regulation of Gene_expression of Ptgir 3 0.51 2.38 0.81 100.00
116 INT217125 Negative_regulation of Gene_expression of Dld 1 0.41 0.72 0 100.00
117 INT115992 Positive_regulation of Gene_expression of TRIM32 1 0.00 0.76 0.1 100.00
118 INT115993 Positive_regulation of TRIM32 1 0.00 0.75 0.1 100.00
119 INT324608 Positive_regulation of Binding of SNCG 1 0.41 1 0 100.00
120 INT142753 Gene_expression of Lcn2 28 0.76 10.03 3.62 100.00
121 INT48312 Gene_expression of NTRK1 72 0.78 38.21 22.24 100.00
122 INT151029 Positive_regulation of Gene_expression of Lcn2 8 0.68 4.04 2.65 100.00
123 INT44490 Positive_regulation of Akr7a3 2 0.30 0.2 0.46 100.00
124 INT111295 Binding of SLC15A1 4 0.47 0.22 0.43 100.00
125 INT178497 Positive_regulation of Gene_expression of Angpt1 4 0.19 3.65 0.39 100.00
126 INT231991 Negative_regulation of Gene_expression of Tsp1 6 0.51 7.3 0.18 100.00
127 INT190454 Regulation of NANOG 2 0.30 1.29 0.17 100.00
128 INT269876 Binding of Sox17 1 0.48 0.72 0 100.00
129 INT286104 Negative_regulation of Mutyh 1 0.35 2.24 0 100.00
130 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 99.98
131 INT175520 Gene_expression of Igf2 43 0.78 48.93 1.21 99.98
132 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 99.98
133 INT175512 Positive_regulation of Gene_expression of Igf2 16 0.70 22.75 0.08 99.98
134 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 99.98
135 INT38670 Positive_regulation of Gene_expression of KRT20 68 0.69 23.25 5.55 99.98
136 INT263878 Positive_regulation of Rigs1 1 0.05 2.57 0.07 99.98
137 INT21503 Binding of Ptgs1 45 0.48 15.6 22.29 99.98
138 INT80779 Positive_regulation of Hbb-ar 10 0.41 2.48 3.29 99.98
139 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.96
140 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53 99.96
141 INT129189 Negative_regulation of ATF3 2 0.58 16.51 0.33 99.96
142 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.96
143 INT263877 Gene_expression of Rigs1 1 0.08 11.58 0.03 99.96
144 INT69993 Positive_regulation of Gene_expression of Cpox 93 0.55 69.4 22.05 99.96
145 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 99.96
146 INT322593 Gene_expression of RPS18 1 0.05 2.51 0.03 99.96
147 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 99.96
148 INT76405 Positive_regulation of Hmox2 21 0.43 12.77 8.99 99.96
149 INT328040 Localization of Lias 1 0.41 5.11 1.52 99.96
150 INT60344 Regulation of Gene_expression of Mras 1 0.15 0.41 0.13 99.96
151 INT263873 Positive_regulation of Gene_expression of Rigs1 1 0.05 1.27 0.03 99.96
152 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 99.92
153 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 99.92
154 INT104979 Gene_expression of MITF 51 0.62 54.83 6.91 99.92
155 INT66227 Gene_expression of COX18 41 0.50 26.91 6.26 99.92
156 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 99.92
157 INT16814 Negative_regulation of COX5A 74 0.57 33.72 28.63 99.92
158 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61 99.92
159 INT217823 Positive_regulation of Gene_expression of MITF 8 0.01 7.1 0.55 99.92
160 INT326136 Binding of Snai1 1 0.04 1.23 0 99.92
161 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37 99.92
162 INT214071 Negative_regulation of Transcription of RARA 3 0.37 1.77 0.07 99.92
163 INT23834 Negative_regulation of AKR1B1 8 0.55 3.79 1.15 99.92
164 INT26641 Gene_expression of Fdft1 4 0.20 1.61 3.15 99.92
165 INT10442 Negative_regulation of CNR1 47 0.59 20.88 20.2 99.92
166 INT82737 Regulation of Hmox2 7 0.14 4.6 2.44 99.92
167 INT2336 Negative_regulation of Lct 51 0.58 33.79 13.73 99.92
168 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.90
169 INT288233 Localization of TYMS 2 0.22 2.17 0.04 99.90
170 INT140766 Positive_regulation of Unc5a 1 0.06 0.31 0 99.90
171 INT50016 Positive_regulation of ARHGAP4 3 0.49 1.8 0.58 99.90
172 INT57222 Gene_expression of ATF3 22 0.78 54.71 3.28 99.88
173 INT234676 Gene_expression of SNCG 4 0.78 63.59 0.08 99.88
174 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 99.88
175 INT92383 Gene_expression of KRAS 38 0.65 32.94 1.32 99.88
176 INT57223 Binding of ATF3 5 0.37 6.3 0.32 99.88
177 INT324607 Positive_regulation of Gene_expression of SNCG 1 0.61 10.34 0 99.88
178 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 99.88
179 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 99.88
180 INT182787 Binding of ETV3 14 0.37 25.44 0.37 99.88
181 INT350437 Regulation of Binding of ATF3 1 0.45 2.52 0 99.88
182 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02 99.88
183 INT182621 Localization of MLH1 9 0.64 9.31 0.12 99.88
184 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18 99.88
185 INT90097 Localization of PTGS2 15 0.69 6.14 6.63 99.88
186 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42 99.86
187 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 99.86
188 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 99.86
189 INT126478 Gene_expression of Cxcl12 78 0.77 58.69 8.01 99.86
190 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 99.86
191 INT129191 Regulation of ATF3 8 0.61 17.04 2.54 99.86
192 INT269217 Gene_expression of SNAI1 81 0.76 80.49 2.26 99.86
193 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.86
194 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27 99.86
195 INT181107 Gene_expression of Epcam 45 0.73 44.33 1.96 99.86
196 INT343192 Gene_expression of ACSL4 1 0.75 20.21 0.35 99.86
197 INT195681 Positive_regulation of Negative_regulation of APC 5 0.47 3.9 0 99.86
198 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 99.86
199 INT8786 Negative_regulation of ALDH7A1 27 0.52 12.81 4.76 99.86
200 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89 99.86
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