D:Colonic Polyps

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pChart

Disease Term
Synonyms Colon Polyps, COLONIC POLYP, POLYP COLONIC, Polyp Of Colon, Polyp Of Colon Disorder, Polyp Of The Colon, POLYPS COLONIC, Polyps Of The Colon
Documents 25
Hot Single Events 5
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Colonic Polyps. They are ordered first by their relevance to Colonic Polyps and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
2 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48 5.00
3 INT239087 Binding of SST and Negative_regulation of Localization of GH1 1 0.19 0.36 0.24 5.00
4 INT286113 Binding of Fap and Rpe65 1 0.04 1.97 0 5.00
5 INT286114 Binding of MSH6 and Mutyh 1 0.17 0 0 5.00
6 INT286111 Binding of Rpa3 and Mutyh 1 0.30 0 0 5.00
7 INT286112 Binding of Apc and Afap1 1 0.05 0.71 0 5.00
8 INT286110 Binding of Rpe65 and Gopc 1 0.01 1.97 0 5.00
9 INT286115 Binding of APEX1 and Mutyh 1 0.10 0 0 5.00
10 INT286109 Binding of Pcna and Mutyh 1 0.30 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Colonic Polyps. They are ordered first by their pain relevance and then by number of times they were reported in Colonic Polyps. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 98.96
2 INT86813 Gene_expression of Pla2g4a 26 0.75 42.31 10.07 98.30
3 INT86816 Negative_regulation of Gene_expression of Pla2g4a 3 0.50 2.27 0.93 98.30
4 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 91.20
5 INT205888 Positive_regulation of Gene_expression of Pla2g4a 7 0.67 8 0.9 86.80
6 INT205894 Regulation of Gene_expression of Pla2g4a 3 0.52 1.9 0.33 76.80
7 INT99176 Positive_regulation of Fap 4 0.13 7.5 0.22 75.64
8 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 70.08
9 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 68.32
10 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 65.80
11 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 64.08
12 INT113399 Positive_regulation of Pla2g4a 36 0.67 33.83 18.78 62.36
13 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 54.56
14 INT208551 Gene_expression of Mutyh 6 0.48 6.28 0.12 53.36
15 INT286105 Positive_regulation of Mutyh 1 0.36 1.94 0.04 52.40
16 INT134298 Gene_expression of Ptges2 96 0.54 56.52 17.19 49.96
17 INT134297 Positive_regulation of Gene_expression of Ptges2 22 0.41 13.12 4.97 49.96
18 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 43.16
19 INT4488 Gene_expression of TSHB 10 0.41 4.69 3.09 43.16
20 INT57018 Gene_expression of GANAB 9 0.08 3.76 1.79 43.16
21 INT55047 Gene_expression of GNRHR 8 0.78 5.2 0.53 43.16
22 INT131384 Binding of Mutyh 5 0.26 2.41 0.78 42.28
23 INT286104 Negative_regulation of Mutyh 1 0.35 2.24 0 42.28
24 INT145328 Negative_regulation of Scrib 25 0.16 26.79 2.66 40.24
25 INT108325 Gene_expression of Scrib 26 0.39 48.33 1.39 40.24
26 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 37.84
27 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 37.84
28 INT15607 Localization of GNRHR 14 0.62 7.56 2.3 35.84
29 INT252 Localization of GH1 529 0.80 227.4 122.05 30.64
30 INT177342 Negative_regulation of SRGN 15 0.28 5.66 0.04 30.48
31 INT425 Localization of PRL 455 0.81 189.64 144.8 30.32
32 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 22.36
33 INT57691 Regulation of Gene_expression of Ptger2 23 0.40 17.08 4.61 18.16
34 INT18156 Gene_expression of Fap 18 0.73 27.02 1.46 13.68
35 INT443 Localization of POMC 1020 0.81 284.52 443.17 13.12
36 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
37 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
38 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
39 INT695 Binding of POMC 304 0.48 56.66 126.85 5.00
40 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 5.00
41 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 5.00
42 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
43 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 5.00
44 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
45 INT253 Regulation of PRL 184 0.62 47.27 65.79 5.00
46 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9 5.00
47 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
48 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
49 INT249 Localization of GHRH 215 0.80 78.02 51.87 5.00
50 INT5118 Regulation of SST 97 0.62 34.35 51.74 5.00
51 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
52 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 5.00
53 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 5.00
54 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
55 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
56 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41 5.00
57 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 5.00
58 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
59 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
60 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 5.00
61 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
62 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92 5.00
63 INT691 Binding of SST 67 0.48 24.66 32.67 5.00
64 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 5.00
65 INT132161 Gene_expression of MTX1 48 0.58 26.55 32.32 5.00
66 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
67 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
68 INT86437 Binding of IL6 154 0.48 121.22 29.3 5.00
69 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
70 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
71 INT7394 Positive_regulation of Localization of GNRH1 67 0.69 7.22 25.29 5.00
72 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 5.00
73 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 5.00
74 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 5.00
75 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 5.00
76 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
77 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 5.00
78 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
79 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 5.00
80 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 5.00
81 INT987 Localization of TRH 37 0.78 10.53 11.1 5.00
82 INT10009 Positive_regulation of TRH 31 0.67 8.94 11.03 5.00
83 INT103554 Positive_regulation of MTX1 19 0.45 11.23 10 5.00
84 INT34777 Localization of IGF1 82 0.80 42.68 8.62 5.00
85 INT156827 Localization of MRI1 25 0.65 16.06 8.33 5.00
86 INT48725 Gene_expression of IGFBP3 128 0.78 78.83 8.19 5.00
87 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8 5.00
88 INT182320 Binding of MTX1 14 0.18 8.5 7.65 5.00
89 INT91417 Positive_regulation of PTGES 36 0.68 18.45 7.64 5.00
90 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02 5.00
91 INT9683 Binding of GH1 57 0.47 21.14 5.99 5.00
92 INT162328 Regulation of Ptges2 21 0.19 12.07 5.56 5.00
93 INT22943 Positive_regulation of Positive_regulation of Gpt 23 0.47 16.09 5.55 5.00
94 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22 5.00
95 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 5.00
96 INT4378 Regulation of Gene_expression of GH1 26 0.47 10.2 4.61 5.00
97 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91 5.00
98 INT134296 Positive_regulation of Ptges2 20 0.19 14.85 3.8 5.00
99 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68 5.00
100 INT90406 Gene_expression of IL6R 27 0.38 15.74 3.64 5.00
101 INT174816 Binding of IL6R 14 0.09 11.26 3.63 5.00
102 INT48726 Gene_expression of IGFBP1 27 0.67 9.45 3.36 5.00
103 INT180250 Positive_regulation of GLUL 23 0.29 7.57 3.23 5.00
104 INT16130 Binding of IGF1 67 0.48 27.43 2.95 5.00
105 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81 5.00
106 INT17961 Regulation of Pla2g4a 9 0.25 4.86 2.3 5.00
107 INT129895 Gene_expression of HPGD 9 0.75 10.22 2.21 5.00
108 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87 5.00
109 INT78938 Binding of IGFBP3 40 0.45 27.95 1.73 5.00
110 INT3818 Regulation of Apc 13 0.39 12.52 1.68 5.00
111 INT48616 Positive_regulation of IGFBP1 14 0.43 5.62 1.56 5.00
112 INT46736 Negative_regulation of Odc1 10 0.51 7.6 1.39 5.00
113 INT220177 Binding of Apc 21 0.37 15.34 1.37 5.00
114 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36 5.00
115 INT268619 Phosphorylation of Pla2g4a 5 0.69 2.14 1.36 5.00
116 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3 5.00
117 INT36330 Positive_regulation of Positive_regulation of GOT1 4 0.32 4.42 1.26 5.00
118 INT35103 Positive_regulation of Positive_regulation of SLC17A5 5 0.12 7.51 1.25 5.00
119 INT149954 Negative_regulation of Gene_expression of HPGD 4 0.41 4.5 1.12 5.00
120 INT23660 Negative_regulation of Fap 5 0.35 8.93 0.95 5.00
121 INT147880 Regulation of SRGN 28 0.33 13.99 0.9 5.00
122 INT192300 Positive_regulation of Gene_expression of IGFBP1 6 0.60 2.85 0.81 5.00
123 INT184157 Gene_expression of Ptges3 6 0.45 2.93 0.71 5.00
124 INT158836 Positive_regulation of Localization of TRH 7 0.49 2.61 0.67 5.00
125 INT178752 Binding of IGFBP1 8 0.15 4.58 0.61 5.00
126 INT184475 Protein_catabolism of Ptger2 5 0.30 1.85 0.57 5.00
127 INT18168 Protein_catabolism of Gcg 4 0.99 1.17 0.56 5.00
128 INT183629 Gene_expression of Ctnnd2 14 0.75 11.78 0.48 5.00
129 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46 5.00
130 INT214067 Regulation of Scrib 11 0.20 12.48 0.45 5.00
131 INT58679 Gene_expression of Odc1 13 0.78 9.55 0.45 5.00
132 INT73627 Binding of Fap 8 0.36 11.14 0.4 5.00
133 INT260859 Negative_regulation of Binding of IL6R 1 0.06 1.08 0.38 5.00
134 INT225667 Transcription of Apc 3 0.52 3.73 0.32 5.00
135 INT182073 Binding of APEX1 4 0.12 1.72 0.32 5.00
136 INT12531 Localization of GANAB 3 0.09 2.79 0.26 5.00
137 INT171716 Regulation of Fap 4 0.27 4.05 0.23 5.00
138 INT230448 Negative_regulation of MOGS 4 0.41 2.64 0.22 5.00
139 INT260174 Gene_expression of Rpe65 29 0.78 4.2 0.19 5.00
140 INT286108 Negative_regulation of Afap1 1 0.08 3.35 0.18 5.00
141 INT172368 Negative_regulation of Binding of IGF1 3 0.42 1.57 0.18 5.00
142 INT242819 Negative_regulation of Gene_expression of Apc 4 0.37 5.6 0.1 5.00
143 INT239095 Negative_regulation of PTTG1 2 0.32 8.24 0.09 5.00
144 INT58681 Positive_regulation of Gene_expression of Odc1 2 0.70 1.13 0.07 5.00
145 INT239094 Negative_regulation of Binding of GH1 2 0.34 1.61 0.06 5.00
146 INT239092 Positive_regulation of Binding of IGFBP1 1 0.04 0.6 0.04 5.00
147 INT231433 Positive_regulation of Binding of IGFBP3 2 0.34 0.6 0.04 5.00
148 INT286102 Positive_regulation of Fap 5 0.30 8.58 0.04 5.00
149 INT286095 Gene_expression of Afap1 1 0.09 2.42 0.03 5.00
150 INT286106 Positive_regulation of Gene_expression of Mutyh 1 0.36 0.66 0 5.00
151 INT286101 Protein_catabolism of Ctnnd2 1 0.64 1.14 0 5.00
152 INT286097 Binding of Afap1 1 0.05 1.72 0 5.00
153 INT265588 Localization of Fap 4 0.47 5.67 0 5.00
154 INT325678 Negative_regulation of Protein_catabolism of Gcg 1 0.02 0.8 0 5.00
155 INT325690 Binding of MOGS 1 0.36 0.4 0 5.00
156 INT286107 Positive_regulation of Phosphorylation of Fap 1 0.30 3.5 0 5.00
157 INT286100 Binding of Rpa3 1 0.36 0 0 5.00
158 INT286103 Regulation of Gene_expression of Fap 1 0.16 1.49 0 5.00
159 INT286093 Regulation of Binding of Apc 1 0.39 1.08 0 5.00
160 INT201643 Binding of Pcna 2 0.36 0 0 5.00
161 INT286092 Positive_regulation of Afap1 1 0.06 2.48 0 5.00
162 INT286099 Negative_regulation of Gene_expression of Ctnnd2 1 0.41 1.06 0 5.00
163 INT286096 Phosphorylation of Fap 1 0.49 4.87 0 5.00
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