D:Communication Disorders

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pChart

Disease Term
Synonyms Acquired Communication Disorder, ACQUIRED COMMUNICATION DISORDERS, CHILDHOOD COMMUNICATION DISORDER, Childhood Communication Disorders, Communication Disabilities, COMMUNICATION DISABILITY, Communication Disorder, COMMUNICATION DISORDER ACQUIRED, Communication Disorder Childhood, Communication Disorder Developmental, COMMUNICATION DISORDER NEUROGENIC
Documents 47
Hot Single Events 1
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Communication Disorders. They are ordered first by their relevance to Communication Disorders and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT293867 Binding of COL2A1 and MEFV 1 0.01 0.52 0.14 5.00
2 INT209400 Binding of F13A1 and FGG 1 0.01 1.72 0.09 5.00
3 INT293869 Binding of COL2A1 and GREM1 1 0.00 1.11 0 5.00
4 INT293868 Binding of GREM1 and OCM 1 0.00 1.11 0 5.00
5 INT262413 Binding of EPHB1 and ADHD1 1 0.17 0.1 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Communication Disorders. They are ordered first by their pain relevance and then by number of times they were reported in Communication Disorders. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT58550 Gene_expression of SON 8 0.43 0.99 0.88 92.44
2 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 61.16
3 INT326522 Positive_regulation of Gene_expression of HGS 1 0.07 2.62 0.08 57.12
4 INT136927 Gene_expression of HGS 18 0.70 14.42 0.6 56.68
5 INT326523 Negative_regulation of Gene_expression of HGS 1 0.06 2.64 0.08 56.68
6 INT103020 Gene_expression of SGCA 22 0.56 14.29 2.75 51.24
7 INT286174 Positive_regulation of ADAMTS2 2 0.13 0.48 0 33.96
8 INT3060 Negative_regulation of Bche 94 0.59 46.75 18.51 31.68
9 INT209403 Positive_regulation of MYL10 1 0.01 6.28 0.07 20.48
10 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73 14.20
11 INT6852 Localization of TNF 883 0.81 705.95 270.84 6.48
12 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
13 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
14 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
15 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
16 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
17 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
18 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
19 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
20 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
21 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
22 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
23 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
24 INT65500 Gene_expression of App 605 0.78 429.94 98.31 5.00
25 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
26 INT21793 Positive_regulation of Ngf 154 0.70 94.78 85.27 5.00
27 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
28 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 5.00
29 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
30 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
31 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 5.00
32 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 5.00
33 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 5.00
34 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
35 INT6855 Binding of NCOR2 71 0.41 15.64 28.96 5.00
36 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58 5.00
37 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62 5.00
38 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23 5.00
39 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 5.00
40 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 5.00
41 INT11625 Localization of App 98 0.78 55.46 20.86 5.00
42 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 5.00
43 INT20305 Gene_expression of Cyp2e1 53 0.78 19.75 19.54 5.00
44 INT65502 Regulation of App 77 0.62 52.05 19.44 5.00
45 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 5.00
46 INT68347 Negative_regulation of Cyp2d4 34 0.58 7.62 18.35 5.00
47 INT29555 Positive_regulation of CALM1 58 0.69 14.09 17.37 5.00
48 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68 5.00
49 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
50 INT6381 Negative_regulation of Chat 51 0.59 19.68 15.86 5.00
51 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
52 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 5.00
53 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31 5.00
54 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38 5.00
55 INT26973 Gene_expression of Tenc1 59 0.66 27.19 12 5.00
56 INT3845 Gene_expression of GSR 79 0.76 44.69 11.19 5.00
57 INT15054 Gene_expression of Mme 48 0.77 42.52 10.63 5.00
58 INT49129 Positive_regulation of GFAP 35 0.69 28.78 10.38 5.00
59 INT144689 Regulation of RCT 49 0.53 25.91 9.6 5.00
60 INT56985 Gene_expression of MEFV 56 0.71 46.71 9.47 5.00
61 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 5.00
62 INT57665 Negative_regulation of Cyp2e1 35 0.59 8.05 9.29 5.00
63 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 5.00
64 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 5.00
65 INT107087 Positive_regulation of Gene_expression of Cyp2e1 20 0.70 8.89 9.04 5.00
66 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
67 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 5.00
68 INT148703 Gene_expression of NOVA2 73 0.65 18.05 8.3 5.00
69 INT72884 Positive_regulation of Tenc1 13 0.42 14.01 7.67 5.00
70 INT8684 Positive_regulation of ANGPTL5 45 0.69 36.29 7.47 5.00
71 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 5.00
72 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11 5.00
73 INT10507 Positive_regulation of Gene_expression of PTAFR 15 0.61 10.24 6.61 5.00
74 INT9951 Gene_expression of ANGPTL5 45 0.53 37.2 6.44 5.00
75 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 5.00
76 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 5.00
77 INT12183 Negative_regulation of Cyp2d1 11 0.58 3.11 5.49 5.00
78 INT23952 Gene_expression of Cyp2d4 18 0.78 4.76 5.31 5.00
79 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09 5.00
80 INT171019 Gene_expression of SMPD1 26 0.27 12.08 5.08 5.00
81 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06 5.00
82 INT71418 Binding of CES1 42 0.40 29.78 5.01 5.00
83 INT57368 Regulation of ADHD1 39 0.50 42.23 5.01 5.00
84 INT1753 Gene_expression of Ache 38 0.78 15.31 4.58 5.00
85 INT72703 Gene_expression of Ide 79 0.70 45.04 4.47 5.00
86 INT141000 Negative_regulation of GSK 24 0.57 9.46 4.4 5.00
87 INT168418 Positive_regulation of RCT 32 0.55 20.2 4.07 5.00
88 INT33735 Binding of ANGPTL5 39 0.32 14.23 3.66 5.00
89 INT55516 Gene_expression of Cyp2d1 5 0.60 0.83 3.58 5.00
90 INT8778 Regulation of Ache 17 0.62 3.7 3.57 5.00
91 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52 5.00
92 INT134786 Gene_expression of Adam10 17 0.68 7.61 3.29 5.00
93 INT100688 Gene_expression of SRC 28 0.75 15.51 3.08 5.00
94 INT329148 Gene_expression of CNTNAP2 17 0.76 6 2.95 5.00
95 INT108501 Binding of ARSD 14 0.32 11.5 2.93 5.00
96 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 5.00
97 INT50080 Binding of APOE 38 0.45 29.61 2.67 5.00
98 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66 5.00
99 INT93207 Negative_regulation of Cyp4a3 11 0.36 4.32 2.63 5.00
100 INT96693 Binding of COL2A1 45 0.46 37.11 2.61 5.00
101 INT51683 Regulation of Gene_expression of PTAFR 11 0.60 5.06 2.59 5.00
102 INT23775 Regulation of S100B 24 0.62 16.75 2.57 5.00
103 INT210527 Positive_regulation of Gene_expression of Tenc1 14 0.38 6.37 2.45 5.00
104 INT1864 Regulation of Bche 18 0.47 6.18 2.44 5.00
105 INT183668 Binding of SGCA 15 0.36 9.86 2.42 5.00
106 INT201683 Phosphorylation of GSK 15 0.80 6.6 2.01 5.00
107 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85 5.00
108 INT121117 Regulation of Protein_catabolism of App 10 0.62 6.41 1.78 5.00
109 INT58563 Negative_regulation of S100B 13 0.51 11.75 1.77 5.00
110 INT176629 Gene_expression of GREM1 9 0.10 6.89 1.66 5.00
111 INT98788 Negative_regulation of EPHB1 11 0.37 3.65 1.64 5.00
112 INT137281 Regulation of Csi 15 0.39 1.2 1.56 5.00
113 INT19181 Gene_expression of Bche 35 0.68 16.93 1.52 5.00
114 INT212466 Regulation of EPHB1 7 0.37 5.72 1.42 5.00
115 INT125796 Regulation of Gene_expression of APP 8 0.59 5.95 1.41 5.00
116 INT166274 Gene_expression of EPHB1 14 0.55 8.2 1.19 5.00
117 INT263019 Gene_expression of DEFA6 4 0.25 4.14 1.17 5.00
118 INT219950 Negative_regulation of Gene_expression of SRC 2 0.29 1.32 1.15 5.00
119 INT79780 Gene_expression of Cyp4a3 14 0.56 5.19 1.12 5.00
120 INT208427 Regulation of T 3 0.25 3.28 1.08 5.00
121 INT56200 Negative_regulation of Negative_regulation of Chat 3 0.25 1.38 0.88 5.00
122 INT148271 Regulation of SGCA 10 0.37 5.89 0.86 5.00
123 INT157382 Gene_expression of Csi 17 0.58 3.93 0.82 5.00
124 INT252166 Negative_regulation of Cdr1 6 0.17 2.42 0.69 5.00
125 INT149928 Positive_regulation of Negative_regulation of Cyp2e1 2 0.50 0.35 0.68 5.00
126 INT125635 Negative_regulation of Cyp2c6 3 0.59 0.18 0.66 5.00
127 INT191978 Positive_regulation of Gene_expression of Ide 16 0.63 6.8 0.65 5.00
128 INT169167 Positive_regulation of GREM1 1 0.08 1.83 0.6 5.00
129 INT225462 Positive_regulation of Positive_regulation of APP 3 0.44 1.41 0.55 5.00
130 INT334212 Negative_regulation of DLEU1 2 0.28 8.84 0.53 5.00
131 INT230244 Positive_regulation of Phosphorylation of GSK 4 0.49 1.43 0.36 5.00
132 INT61236 Gene_expression of Cyp2c6 3 0.78 1.55 0.35 5.00
133 INT264685 Gene_expression of TARDBP 4 0.61 8.8 0.31 5.00
134 INT246100 Positive_regulation of Gene_expression of Adam10 4 0.61 1.2 0.3 5.00
135 INT58627 Positive_regulation of Cyp2c12 2 0.49 0.42 0.27 5.00
136 INT142213 Protein_catabolism of Csi 2 0.33 0.37 0.26 5.00
137 INT76159 Gene_expression of CEACAM1 5 0.65 5.12 0.24 5.00
138 INT191971 Regulation of Gene_expression of Ide 5 0.45 1.97 0.2 5.00
139 INT246101 Negative_regulation of Phosphorylation of GSK 3 0.42 1.34 0.15 5.00
140 INT96772 Positive_regulation of Gene_expression of APOE 5 0.66 5.44 0.14 5.00
141 INT188611 Negative_regulation of AGPS 2 0.42 0.47 0.12 5.00
142 INT51883 Negative_regulation of ADAMTS2 3 0.15 0.74 0.11 5.00
143 INT293876 Localization of OCM 1 0.05 0.7 0.1 5.00
144 INT158146 Gene_expression of Ranbp1 2 0.04 3.09 0.09 5.00
145 INT195204 Regulation of Gene_expression of Tenc1 3 0.25 2.37 0.09 5.00
146 INT252167 Negative_regulation of COG1 1 0.42 0.18 0.08 5.00
147 INT293877 Binding of OCM 1 0.03 1.68 0.08 5.00
148 INT220709 Regulation of DOCK3 1 0.07 0.67 0.06 5.00
149 INT185989 Localization of GREM1 2 0.11 2.41 0.05 5.00
150 INT209405 Regulation of Binding of CSF2 2 0.28 1.17 0.04 5.00
151 INT264054 Negative_regulation of Negative_regulation of Bche 6 0.41 2.49 0.04 5.00
152 INT209407 Positive_regulation of FGG 1 0.24 1.59 0.03 5.00
153 INT216071 Regulation of ENOSF1 2 0.17 0 0.03 5.00
154 INT286173 Gene_expression of ADAMTS2 2 0.13 0.49 0.03 5.00
155 INT264053 Positive_regulation of Negative_regulation of Cyp2d4 1 0.25 0.18 0.03 5.00
156 INT219949 Positive_regulation of TTTY1 1 0.10 0.34 0 5.00
157 INT326073 Transcription of APOE 2 0.51 1.94 0 5.00
158 INT209402 Regulation of Gene_expression of FGG 1 0.16 1.79 0 5.00
159 INT209406 Gene_expression of FGG 2 0.45 2.93 0 5.00
160 INT334211 Positive_regulation of Gene_expression of TARDBP 1 0.32 3.03 0 5.00
161 INT244258 Negative_regulation of Gene_expression of UBE3A 1 0.59 0.82 0 5.00
162 INT293873 Negative_regulation of OCM 1 0.04 0.65 0 5.00
163 INT304217 Negative_regulation of Positive_regulation of skt 1 0.04 0.27 0 5.00
164 INT293874 Positive_regulation of OCM 1 0.05 2 0 5.00
165 INT246099 Negative_regulation of Negative_regulation of Bche 1 0.31 0.66 0 5.00
166 INT334213 Transcription of TARDBP 1 0.24 0.98 0 5.00
167 INT209408 Regulation of FGG 1 0.09 1.79 0 5.00
168 INT244259 Gene_expression of UBE3A 4 0.78 1.91 0 5.00
169 INT304218 Regulation of skt 1 0.03 0.73 0 5.00
170 INT208428 Negative_regulation of ACOT13 1 0.00 0 0 5.00
171 INT216070 Binding of EMC3 1 0.13 0 0 5.00
172 INT293878 Positive_regulation of Localization of GREM1 1 0.01 0.47 0 5.00
173 INT244260 Negative_regulation of UBE3A 1 0.59 0.86 0 5.00
174 INT304216 Positive_regulation of skt 1 0.05 0.27 0 5.00
175 INT293875 Positive_regulation of Gene_expression of GREM1 1 0.01 0.47 0 5.00
176 INT326524 Negative_regulation of Transcription of APOE 1 0.30 1.71 0 5.00
177 INT209401 Gene_expression of MYL10 1 0.01 1.4 0 5.00
178 INT334210 Negative_regulation of Negative_regulation of DLEU1 1 0.09 1.14 0 5.00
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