D:Complex Regional Pain Syndromes

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Disease Term
Synonyms COMPLEX PAIN SYNDROME, Complex Pain Syndromes, CRPS, Crps Complex Regional Pain Syndromes, Pain Syndrome, PAIN SYNDROMES REGIONAL COMPLEX, Reflex Sympathetic Dystrophy, Regional Pain Syndrome, Regional Pain Syndromes
Documents 4641
Hot Single Events 200
Hot Interactions 9

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Complex Regional Pain Syndromes. They are ordered first by their relevance to Complex Regional Pain Syndromes and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT118257 Binding of ENPP1 and SUGT1 1 0.00 0.87 0.16 100.00
2 INT165929 Binding of MME and WSN 1 0.01 0.99 1.16 100.00
3 INT160923 Binding of ACLS and HLA-B 1 0.03 1.44 0.29 100.00
4 INT160924 Binding of ACLS and HLA-A 1 0.01 1.44 0.29 100.00
5 INT150148 Binding of CISH and Myoz1 1 0.01 0.7 0.68 100.00
6 INT65185 Binding of ATRX and Ssr1 1 0.03 1.68 0.49 96.24
7 INT65184 Binding of CSCI and Ssr1 1 0.04 1.67 0.48 96.24
8 INT165627 Binding of COMT and SLTM 1 0.09 0.86 0.88 81.00
9 INT225104 CNR1 Positive_regulation of Gene_expression of RETNLB 1 0.01 1.41 1.14 80.36
10 INT37489 Binding of ADRA1D and Alb 1 0.34 0.84 0.11 74.24
11 INT27764 Binding of FANCB and MYH14 1 0.31 0.28 0.07 65.60
12 INT145886 Binding of CXCL1 and Adipoq 1 0.00 0.77 0.2 58.96
13 INT155644 Binding of CAV1 and HSD11B1 1 0.39 0.77 0.15 56.48
14 INT96782 FAM176C Regulation of Gene_expression of COL1A1 1 0.32 0.05 0 50.00
15 INT222987 Positive_regulation of COL1A1 Positive_regulation of Protein_catabolism of MMP1 1 0.01 0.61 0.03 38.84
16 INT222977 Positive_regulation of COL1A1 Positive_regulation of MMP1 1 0.01 0.61 0.03 38.08
17 INT320600 TNS3 Regulation of CEBPZ 1 0.29 1.96 0.74 29.68
18 INT339287 Binding of Cxcr2 and Cxcl1 1 0.29 0.48 0.24 24.48
19 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25 11.12
20 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 5.00
21 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
22 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
23 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17 5.00
24 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
25 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63 5.00
26 INT335405 Binding of Arntl and Npas2 1 0.28 1.82 1.61 5.00
27 INT315284 PRKG1 Positive_regulation of Nos1 1 0.33 0.85 1.56 5.00
28 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54 5.00
29 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18 5.00
30 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14 5.00
31 INT296950 Tacr1 Negative_regulation of Gene_expression of Cck 1 0.30 0.94 1.11 5.00
32 INT308173 Binding of DRG1 and Tnfrsf1b 1 0.01 1.64 1.1 5.00
33 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 5.00
34 INT335401 Hgf Positive_regulation of Ngf 1 0.30 1.13 1.04 5.00
35 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 5.00
36 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
37 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97 5.00
38 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95 5.00
39 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95 5.00
40 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93 5.00
41 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92 5.00
42 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9 5.00
43 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85 5.00
44 INT339293 Casp1 Regulation of Localization of Il1 1 0.07 1.87 0.83 5.00
45 INT335404 Binding of Arntl and Hspg2 1 0.06 0.93 0.82 5.00
46 INT335403 Binding of Hspg2 and Npas2 1 0.04 0.93 0.82 5.00
47 INT339291 Casp1 Positive_regulation of Il1 2 0.12 1.63 0.8 5.00
48 INT127876 ACE Positive_regulation of Protein_catabolism of CALCA 1 0.28 0.63 0.75 5.00
49 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75 5.00
50 INT308167 Binding of Eln and Tnfrsf1b 1 0.01 0.94 0.71 5.00
51 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
52 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63 5.00
53 INT310712 Gabrg1 Positive_regulation of Gene_expression of PMP22 1 0.35 0.56 0.61 5.00
54 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61 5.00
55 INT202160 Binding of ARSD and CSF1R 1 0.16 1.69 0.59 5.00
56 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56 5.00
57 INT339290 Casp1 Regulation of Gene_expression of Il1 1 0.11 1.38 0.55 5.00
58 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54 5.00
59 INT310701 RPLP0 Regulation of Positive_regulation of PGR 1 0.01 0.49 0.53 5.00
60 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48 5.00
61 INT308170 Binding of thd and Tnfrsf14 1 0.00 1.84 0.46 5.00
62 INT308171 Binding of TNF and thd 1 0.00 1.84 0.45 5.00
63 INT177440 Binding of HPSE and Gnrh1 1 0.00 1.82 0.45 5.00
64 INT310711 Binding of RPLP0 and Gabrg1 1 0.04 0.37 0.45 5.00
65 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43 5.00
66 INT189197 RASGRP1 Positive_regulation of JUN 1 0.07 1.26 0.43 5.00
67 INT311590 EGF Regulation of Gene_expression of CXCL10 1 0.23 0.51 0.43 5.00
68 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43 5.00
69 INT311591 CXCL10 Regulation of Gene_expression of EGF 1 0.23 0.51 0.43 5.00
70 INT278389 Binding of Casp1 and Il1 2 0.09 0.82 0.36 5.00
71 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34 5.00
72 INT222973 NFKBIB Negative_regulation of NFKB2 Negative_regulation of IL6 1 0.00 1.6 0.33 5.00
73 INT222974 NFKBIB Negative_regulation of NFKB2 Negative_regulation of ICAM1 1 0.00 1.6 0.33 5.00
74 INT222976 NFKBIB Negative_regulation of NFKB2 1 0.01 1.58 0.32 5.00
75 INT339294 Il1 Positive_regulation of Gene_expression of Cxcl1 1 0.06 0.53 0.3 5.00
76 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28 5.00
77 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28 5.00
78 INT189200 Binding of CA2 and ITPR3 3 0.03 1.9 0.27 5.00
79 INT222986 PTPRC Positive_regulation of SMN1 1 0.01 0.46 0.26 5.00
80 INT222975 PTPRC Positive_regulation of VIM 1 0.05 0.46 0.26 5.00
81 INT310700 PGR Regulation of Gene_expression of RPLP0 1 0.01 0.37 0.25 5.00
82 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24 5.00
83 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24 5.00
84 INT225118 Foxm1 Positive_regulation of Gene_expression of MMP2 1 0.01 0.34 0.23 5.00
85 INT189199 JUN Positive_regulation of KRT16 1 0.31 0.58 0.22 5.00
86 INT225117 Foxm1 Regulation of Gene_expression of FN1 1 0.01 0.4 0.22 5.00
87 INT225103 ZNF630 Negative_regulation of CNR2 1 0.01 0.17 0.21 5.00
88 INT225097 ZNF630 Negative_regulation of CNR2 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.21 5.00
89 INT189196 RASGRP1 Positive_regulation of SP1 1 0.05 0.63 0.21 5.00
90 INT339292 Il1 Positive_regulation of Gene_expression of Ptger2 1 0.02 0.4 0.2 5.00
91 INT174861 Binding of FGF2 and VEGFA 1 0.34 0.59 0.2 5.00
92 INT225099 ZNF630 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.2 5.00
93 INT206089 Negative_regulation of FOSB Negative_regulation of Gene_expression of PTGS2 1 0.00 0.97 0.19 5.00
94 INT206081 IL6ST Negative_regulation of IL6 1 0.11 0.81 0.17 5.00
95 INT225096 ZNF630 Positive_regulation of ZNF630 Positive_regulation of SMN1 1 0.00 0.11 0.17 5.00
96 INT225102 ZNF630 Positive_regulation of SMN1 1 0.00 0.11 0.17 5.00
97 INT206059 IL6 Positive_regulation of INS 1 0.02 1.16 0.16 5.00
98 INT206070 ANG Positive_regulation of Transcription of IL6 1 0.05 1.5 0.15 5.00
99 INT353897 Negative_regulation of Prkcg Negative_regulation of Localization of Bcl2l11 1 0.08 0.4 0.13 5.00
100 INT206065 EDN1 Positive_regulation of IL6 1 0.03 0.47 0.12 5.00
101 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 5.00
102 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1 5.00
103 INT288219 Cigs1 Regulation of Nrgn 1 0.00 0.87 0.1 5.00
104 INT206042 Negative_regulation of FDPS Negative_regulation of Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
105 INT222984 TNF Positive_regulation of Positive_regulation of FN1 1 0.05 0.72 0.09 5.00
106 INT206054 RAC1 Positive_regulation of STAT3 1 0.07 0.11 0.09 5.00
107 INT189195 Binding of C4A and C4B 1 0.14 2.45 0.09 5.00
108 INT206075 Negative_regulation of FDPS Negative_regulation of Binding of GGPS1 1 0.01 0 0.09 5.00
109 INT206078 Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
110 INT206072 ANG Positive_regulation of IL6 1 0.05 0.5 0.08 5.00
111 INT222983 TNF Positive_regulation of Positive_regulation of COL1A1 1 0.01 0.71 0.08 5.00
112 INT310113 Binding of SET and TP53INP2 1 0.15 0.05 0.08 5.00
113 INT206080 ANG Regulation of Gene_expression of IL6 1 0.03 0.4 0.07 5.00
114 INT227418 Binding of DLAT and Pdc 1 0.05 1.01 0.07 5.00
115 INT206063 ANG Positive_regulation of Gene_expression of KRT20 1 0.00 1.01 0.07 5.00
116 INT310110 SET Positive_regulation of Localization of POMT1 1 0.08 0 0.05 5.00
117 INT189202 Binding of C4B and HAS2 1 0.02 1.25 0.05 5.00
118 INT206087 RAC1 Positive_regulation of Gene_expression of STAT3 1 0.08 0.05 0.05 5.00
119 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04 5.00
120 INT222982 TNF Positive_regulation of Localization of FN1 1 0.05 0.56 0.04 5.00
121 INT206073 Negative_regulation of RAC1 Positive_regulation of IL6 1 0.14 0.06 0.04 5.00
122 INT206067 Gene_expression of RAC1 Positive_regulation of Positive_regulation of IL6 1 0.16 0.07 0.04 5.00
123 INT189198 Binding of C4A and SERPINF1 1 0.12 1.17 0.04 5.00
124 INT206068 RAC1 Positive_regulation of IL6 1 0.16 0.06 0.04 5.00
125 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04 5.00
126 INT222980 TNF Positive_regulation of Localization of COL1A1 1 0.01 0.56 0.04 5.00
127 INT206071 IRF6 Positive_regulation of Positive_regulation of IL1B 1 0.00 0.58 0.03 5.00
128 INT206076 IL6 Positive_regulation of Positive_regulation of STAT3 1 0.19 0.3 0.03 5.00
129 INT206061 RAC1 Positive_regulation of Positive_regulation of STAT3 1 0.07 0.43 0.03 5.00
130 INT206085 FDPS Positive_regulation of AGFG1 1 0.00 0.4 0 5.00
131 INT206058 EGFR Negative_regulation of Gene_expression of IL6 1 0.07 0.62 0 5.00
132 INT206079 ANG Regulation of KRT20 1 0.00 0.54 0 5.00
133 INT206069 ANG Positive_regulation of Gene_expression of IL6 1 0.05 0.51 0 5.00
134 INT310114 Binding of ENOSF1 and TP53INP2 1 0.04 0 0 5.00
135 INT206088 IL6 Positive_regulation of JAK1 1 0.18 0.05 0 5.00
136 INT189203 CHGB Regulation of CA2 1 0.04 0.95 0 5.00
137 INT206178 Foxm1 Positive_regulation of Protein_catabolism of Olr1 1 0.00 0.47 0 5.00
138 INT206086 LDLR Positive_regulation of Localization of IL6 1 0.03 0.42 0 5.00
139 INT206060 FDPS Positive_regulation of AKT1 1 0.00 0.4 0 5.00
140 INT206055 F2 Positive_regulation of Gene_expression of IL6 1 0.01 1.24 0 5.00
141 INT189201 CHGB Regulation of Localization of CA2 1 0.04 0.95 0 5.00
142 INT206082 IL6 Positive_regulation of Gene_expression of CCL2 1 0.07 0.3 0 5.00
143 INT206180 Foxm1 Positive_regulation of Transcription of Olr1 1 0.00 0.48 0 5.00
144 INT310115 Binding of NOVA2 and SET 1 0.12 0 0 5.00
145 INT206077 RAC1 Positive_regulation of Phosphorylation of STAT3 1 0.07 0.35 0 5.00
146 INT310112 Binding of NOVA2 and TP53INP2 1 0.07 0 0 5.00
147 INT339288 Binding of Hprt1 and Il1 1 0.09 0.05 0 5.00
148 INT206181 FDPS Positive_regulation of ras 1 0.00 0.4 0 5.00
149 INT206084 EGF Negative_regulation of Gene_expression of IL6 1 0.05 0.61 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Complex Regional Pain Syndromes. They are ordered first by their pain relevance and then by number of times they were reported in Complex Regional Pain Syndromes. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT146091 Negative_regulation of IFNAR1 6 0.25 9.12 4.86 100.00
2 INT81229 Binding of COL1A1 24 0.35 12.07 3.3 100.00
3 INT91013 Binding of IFNAR1 9 0.46 8.7 2.74 100.00
4 INT82876 Regulation of IFNAR1 6 0.26 6.69 3.73 100.00
5 INT19965 Positive_regulation of COL1A1 23 0.45 14.49 4.38 100.00
6 INT49191 Gene_expression of IFNAR1 14 0.41 9.96 3.84 100.00
7 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98 100.00
8 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 100.00
9 INT118258 Positive_regulation of ENPP1 3 0.62 4.26 1.16 100.00
10 INT84909 Positive_regulation of SUGT1 22 0.08 22.01 5.43 100.00
11 INT138695 Positive_regulation of Mks1 1 0.01 2.16 1.03 100.00
12 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 100.00
13 INT308015 Phosphorylation of IFNAR1 1 0.27 1.11 0.28 100.00
14 INT93916 Positive_regulation of IFNAR1 7 0.25 5.58 1.09 100.00
15 INT149762 Regulation of MAS1 8 0.31 5.34 1.61 100.00
16 INT89520 Regulation of COL1A1 8 0.32 3.21 0.66 100.00
17 INT163709 Regulation of Negative_regulation of COL1A1 1 0.29 0.93 0.34 100.00
18 INT24020 Positive_regulation of HPS1 6 0.44 6.14 1.08 100.00
19 INT280858 Localization of IFNAR1 5 0.39 4.5 1.09 100.00
20 INT112536 Regulation of Regulation of Mrpl40 1 0.00 1.58 1.3 100.00
21 INT112537 Regulation of Mrpl40 1 0.00 1.58 1.3 100.00
22 INT96116 Transcription of COL1A1 10 0.44 4.57 1.81 100.00
23 INT22353 Positive_regulation of Cps1 6 0.17 0.98 1.14 100.00
24 INT163028 Negative_regulation of Negative_regulation of IFNAR1 1 0.05 0.86 0.73 100.00
25 INT109297 Negative_regulation of WSN 3 0.05 2.13 1.31 100.00
26 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 100.00
27 INT161394 Binding of Mks1 2 0.02 1.52 0.62 100.00
28 INT79261 Positive_regulation of Gene_expression of COL1A1 24 0.36 7.49 2.45 100.00
29 INT84646 Binding of PDHA1 2 0.32 1.36 0.8 100.00
30 INT52740 Binding of ACLS 5 0.31 3 0.54 100.00
31 INT958 Negative_regulation of ATRX 6 0.58 2.92 1.25 100.00
32 INT3364 Binding of SGCG 87 0.47 31.93 17.24 100.00
33 INT35269 Localization of SGCG 38 0.78 14.68 9.01 100.00
34 INT167588 Localization of HPS1 3 0.65 1.24 0.9 100.00
35 INT17821 Gene_expression of Pls1 4 0.32 2.19 1.96 100.00
36 INT16188 Positive_regulation of Pls1 4 0.19 3.07 2.85 100.00
37 INT148892 Binding of HPS1 13 0.37 19.21 3.35 100.00
38 INT148891 Positive_regulation of Binding of HPS1 1 0.07 0.37 0.22 100.00
39 INT84512 Binding of Myoz1 7 0.30 4.48 1.7 100.00
40 INT146303 Binding of PHGDH 7 0.36 4.7 1.42 99.98
41 INT80784 Regulation of BCS1L 9 0.39 7.63 1.47 99.98
42 INT215301 Binding of PQBP1 9 0.27 10.36 0.59 99.96
43 INT3002 Binding of SUGT1 62 0.24 55.9 14.91 99.94
44 INT18894 Gene_expression of CPP 44 0.77 23.05 23.05 99.94
45 INT25834 Positive_regulation of Dbp 59 0.68 24.34 9.32 99.92
46 INT33567 Gene_expression of CALM1 139 0.67 48.85 56.14 99.90
47 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.88
48 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.88
49 INT89425 Positive_regulation of HLA-DRB3 2 0.59 2.38 0.42 99.88
50 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.84
51 INT1148 Positive_regulation of ecs 38 0.48 25.27 13.1 99.84
52 INT242107 Positive_regulation of SYNM 8 0.38 2.82 2.39 99.78
53 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 99.76
54 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 99.76
55 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 99.76
56 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02 99.68
57 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 99.68
58 INT13354 Transcription of TNF 108 0.72 85.81 42.32 99.64
59 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.58
60 INT92507 Positive_regulation of Binding of Vwf 1 0.66 5.46 0.46 99.54
61 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13 99.54
62 INT37219 Gene_expression of TACR1 56 0.78 32.4 54.16 99.52
63 INT92446 Positive_regulation of Gene_expression of TACR1 4 0.35 2.68 4.5 99.52
64 INT51014 Transcription of IL2 42 0.71 21.56 12.7 99.48
65 INT125106 Gene_expression of PRKRA 2 0.13 2.35 0.3 99.48
66 INT89426 Binding of HLA-DRB3 2 0.41 1.77 1.32 99.42
67 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78 99.42
68 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19 99.42
69 INT34358 Binding of MME 13 0.37 7.25 5.14 99.40
70 INT10888 Binding of Vwf 32 0.46 22.87 5.21 99.38
71 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 99.36
72 INT2649 Regulation of Calca 433 0.62 146.05 330.95 99.28
73 INT101013 Regulation of HLA-A 7 0.33 6.7 1.8 99.22
74 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.20
75 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46 99.20
76 INT105920 Binding of SLC9A3R2 5 0.36 1.99 1.75 99.20
77 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 99.16
78 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 99.16
79 INT78493 Negative_regulation of F3 11 0.27 8.35 3.76 99.04
80 INT165571 Gene_expression of ATP1A3 1 0.09 1.22 0.24 99.04
81 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 99.04
82 INT37908 Regulation of Negative_regulation of Tbxa2r 1 0.38 0.94 0.44 99.04
83 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 98.96
84 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 98.96
85 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9 98.96
86 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 98.96
87 INT69035 Positive_regulation of Casp1 43 0.69 25.18 10.67 98.96
88 INT205692 Positive_regulation of Positive_regulation of Casp1 5 0.46 3 2.44 98.96
89 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 98.92
90 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 98.92
91 INT118311 Binding of Slc9a3r2 5 0.45 2.03 1.49 98.84
92 INT165572 Gene_expression of SGCE 1 0.09 1.22 0.24 98.76
93 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94 98.76
94 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 98.74
95 INT2383 Positive_regulation of CP 33 0.67 25.41 15.38 98.72
96 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 98.72
97 INT198136 Positive_regulation of BCL2A1 7 0.67 5.72 5.05 98.68
98 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 98.68
99 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85 98.64
100 INT49129 Positive_regulation of GFAP 35 0.69 28.78 10.38 98.56
101 INT165570 Gene_expression of THAP1 2 0.08 2.13 0.24 98.48
102 INT32519 Positive_regulation of Terc 5 0.36 4.41 1.41 98.48
103 INT2792 Gene_expression of Mb 91 0.76 41.56 10.25 98.40
104 INT24569 Negative_regulation of Pain1 26 0.41 21.82 21.08 98.36
105 INT25607 Binding of Il1 82 0.47 64.4 23.9 98.32
106 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 98.32
107 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 98.32
108 INT103298 Binding of CALCR 5 0.47 6.03 2.15 98.28
109 INT29394 Gene_expression of Adra1a 9 0.77 3.62 3.91 98.28
110 INT29395 Positive_regulation of Gene_expression of Adra1a 2 0.50 1.64 1.57 98.28
111 INT17451 Positive_regulation of Tst 23 0.67 8.85 9.52 98.24
112 INT4781 Gene_expression of TH 68 0.73 26.92 24.01 98.24
113 INT121052 Binding of NOS2 3 0.35 3.12 1.12 98.24
114 INT7439 Positive_regulation of CFP 52 0.67 19.97 17.87 98.04
115 INT53683 Negative_regulation of Gene_expression of ITGB2 10 0.57 9.11 3.2 98.04
116 INT67333 Negative_regulation of ITGB2 10 0.41 6.92 3.06 98.04
117 INT53684 Negative_regulation of Gene_expression of ITGAM 23 0.59 14.36 5.66 98.04
118 INT71732 Negative_regulation of ITGAM 3 0.41 2 1 98.04
119 INT4528 Negative_regulation of Sell 12 0.58 4.76 4.22 98.04
120 INT104300 Negative_regulation of Gene_expression of Sell 8 0.58 3.46 1.91 98.04
121 INT6699 Positive_regulation of ADRA1D 65 0.70 22.72 20.31 98.04
122 INT69592 Positive_regulation of PSMD1 27 0.70 17.83 18.98 98.00
123 INT127565 Positive_regulation of ENC1 2 0.39 11.67 11.82 98.00
124 INT151747 Positive_regulation of PSMD2 26 0.68 17.48 17.89 98.00
125 INT7134 Localization of KNG1 127 0.79 65.73 67.97 98.00
126 INT150934 Gene_expression of GCH1 17 0.78 14.54 17.53 97.96
127 INT22454 Regulation of Crp 213 0.62 160.67 49.24 97.96
128 INT114395 Positive_regulation of Nlrp1a 15 0.45 4.61 15.37 97.96
129 INT64676 Gene_expression of ANXA5 11 0.75 13.48 2.11 97.96
130 INT12608 Regulation of CNR1 62 0.60 24.36 36.02 97.88
131 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34 97.84
132 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 97.84
133 INT87434 Gene_expression of Sell 38 0.77 21.95 8.51 97.84
134 INT141151 Regulation of PSMD1 16 0.40 8.19 5.86 97.80
135 INT157479 Negative_regulation of Localization of TIPRL 1 0.37 1.24 0.34 97.72
136 INT138997 Gene_expression of Dyt1 2 0.67 1.91 0.37 97.68
137 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 97.68
138 INT17262 Negative_regulation of Plat 17 0.59 15.14 6.36 97.64
139 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 97.64
140 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74 97.64
141 INT25152 Gene_expression of SAA1 37 0.75 53.56 8.07 97.60
142 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 97.60
143 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8 97.52
144 INT20348 Negative_regulation of Tbxa2r 47 0.59 19.88 7.68 97.52
145 INT157482 Gene_expression of TIPRL 3 0.58 5.46 1.61 97.44
146 INT157481 Localization of TIPRL 1 0.65 0.62 0.17 97.44
147 INT157480 Positive_regulation of Localization of TIPRL 1 0.43 0.62 0.17 97.44
148 INT157483 Positive_regulation of Gene_expression of TIPRL 1 0.43 0.62 0.17 97.44
149 INT90201 Binding of Trp53inp1 1 0.00 0.81 0.81 97.40
150 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 97.32
151 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 97.28
152 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 97.20
153 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 97.20
154 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 97.16
155 INT29368 Binding of ECT 25 0.41 11.65 5.81 97.12
156 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 97.12
157 INT9106 Positive_regulation of F3 8 0.22 4.92 1.85 97.04
158 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 97.04
159 INT4297 Negative_regulation of CFP 21 0.42 12.7 10.29 97.04
160 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87 96.96
161 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 96.76
162 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 96.76
163 INT19575 Negative_regulation of Positive_regulation of Abat 14 0.43 2.07 11.05 96.76
164 INT20102 Gene_expression of Serpine1 102 0.78 65.99 12.61 96.68
165 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 96.60
166 INT58456 Gene_expression of HFE 10 0.58 7.68 1.65 96.40
167 INT8779 Binding of TAC1 50 0.47 11.19 25.57 96.40
168 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 96.40
169 INT58457 Positive_regulation of HFE 3 0.28 2.75 1.04 96.36
170 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58 96.28
171 INT8518 Localization of Ifng 53 0.81 36.68 24.13 96.28
172 INT55309 Positive_regulation of Ssr1 20 0.46 5.97 5.74 96.24
173 INT160925 Transcription of HLA-A 1 0.31 1.41 0.24 96.08
174 INT93007 Regulation of Gene_expression of CALM1 7 0.41 3.47 6.08 96.08
175 INT38241 Positive_regulation of TMPRSS15 1 0.66 0.97 0.18 96.04
176 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 95.92
177 INT11696 Gene_expression of HLA-A 50 0.78 41.25 14.1 95.84
178 INT175652 Positive_regulation of BPHL 9 0.44 17.98 1.14 95.80
179 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55 95.72
180 INT213431 Positive_regulation of Gene_expression of MMRN1 15 0.24 9.91 1.96 95.72
181 INT66797 Positive_regulation of Transcription of PHKG1 1 0.26 0.28 0.1 95.72
182 INT66796 Transcription of PHKG1 1 0.36 0.28 0.1 95.72
183 INT291559 Negative_regulation of NMS 1 0.19 0.33 0.1 95.72
184 INT626 Localization of CALCA 289 0.81 125.39 221.15 95.68
185 INT4776 Localization of TAC1 82 0.78 16.89 45.21 95.68
186 INT175482 Positive_regulation of Gene_expression of CALM1 12 0.44 3.47 6.54 95.68
187 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 95.64
188 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 95.64
189 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99 95.64
190 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 95.36
191 INT22715 Positive_regulation of Gene_expression of Pth 29 0.64 22.53 2.31 95.36
192 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26 95.16
193 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 95.16
194 INT48642 Positive_regulation of TCEA1 92 0.70 24.59 53.64 95.04
195 INT9084 Positive_regulation of Nppb 74 0.70 69.77 11.85 94.92
196 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3 94.76
197 INT17544 Negative_regulation of Gene_expression of NPY 3 0.42 1.97 1.05 94.76
198 INT72884 Positive_regulation of Tenc1 13 0.42 14.01 7.67 94.72
199 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 94.60
200 INT5048 Binding of Edn1 55 0.47 18.86 19.16 94.52
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