D:Conduct Disorder

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Disease Term
Synonyms CONDUCT DISORDERS
Documents 127
Hot Single Events 24
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Conduct Disorder. They are ordered first by their relevance to Conduct Disorder and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT258765 Lmo1 Regulation of ADHD1 1 0.05 1.98 0.09 99.60
2 INT184878 Binding of Lmo1 and ADHD1 2 0.04 2.33 0.53 61.84
3 INT258762 Binding of Dbh and ADHD1 1 0.08 1.61 0.34 61.84
4 INT258767 Binding of Drd2 and ADHD1 1 0.11 1.14 0.11 61.84
5 INT258763 Binding of Drd5 and ADHD1 1 0.07 1.11 0.31 49.48
6 INT258764 Binding of Drd4 and ADHD1 1 0.08 1.11 0.31 49.48
7 INT258758 Binding of Drd4 and Lmo1 1 0.04 0.64 0.08 49.48
8 INT258756 Binding of Drd5 and Lmo1 1 0.03 0.64 0.08 49.48
9 INT258757 Binding of Drd2 and Rends1 1 0.00 1.26 0.25 19.24
10 INT320701 Binding of SMARCC1 and C1QL3 1 0.00 0.71 0 16.84
11 INT271889 Binding of DRD2 and ANKK1 1 0.23 0.36 0.55 5.00
12 INT271888 Binding of DRD2 and DNAJC7 1 0.14 0.36 0.55 5.00
13 INT255463 Binding of Avp and Avpr1a 1 0.06 0.67 0.54 5.00
14 INT271902 Binding of KCNK1 and Jun 1 0.12 0.08 0.53 5.00
15 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48 5.00
16 INT138384 Binding of Htr1b and ADHD1 2 0.07 1.46 0.42 5.00
17 INT258766 Binding of Csf2 and ADHD1 1 0.01 0.69 0.27 5.00
18 INT321653 Binding of Phc1 and Datd 1 0.00 0.35 0.24 5.00
19 INT258761 Binding of Slc6a3 and ADHD1 1 0.03 0.51 0.12 5.00
20 INT258768 Drd2 Regulation of ADHD1 1 0.14 0.79 0.07 5.00
21 INT304189 Binding of HP and ADHD1 1 0.02 2.59 0.07 5.00
22 INT321651 Binding of Slc6a3 and Uts2r 1 0.04 0.06 0.05 5.00
23 INT321652 Binding of Slc6a3 and Slc6a4 1 0.26 0.07 0.05 5.00
24 INT321654 Binding of Slc6a4 and Uts2r 1 0.05 0.07 0.05 5.00
25 INT304190 Binding of HP and ZFP91 1 0.00 2.74 0.03 5.00
26 INT304191 Binding of SNRPD1 and ADHD1 1 0.01 0.99 0 5.00
27 INT320702 Binding of PMVK and C1QL3 1 0.01 0.06 0 5.00
28 INT262413 Binding of EPHB1 and ADHD1 1 0.17 0.1 0 5.00
29 INT317900 Binding of NCAPH2 and MCPH1 1 0.02 0.53 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Conduct Disorder. They are ordered first by their pain relevance and then by number of times they were reported in Conduct Disorder. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT95048 Negative_regulation of ADHD1 61 0.51 56.01 5.62 100.00
2 INT7581 Binding of ADHD1 132 0.46 135.1 19.73 99.76
3 INT4297 Negative_regulation of CFP 21 0.42 12.7 10.29 99.66
4 INT258745 Binding of Lmo1 3 0.11 5.92 0.84 99.20
5 INT113251 Negative_regulation of soc 5 0.50 4.11 0.24 99.06
6 INT57368 Regulation of ADHD1 39 0.50 42.23 5.01 97.60
7 INT2213 Regulation of EP300 10 0.54 4.72 4.5 97.36
8 INT171514 Binding of EP300 13 0.32 4.32 2.01 97.26
9 INT184853 Gene_expression of ADHD1 87 0.65 89.2 11.8 97.20
10 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8 96.92
11 INT189863 Gene_expression of DRD4 11 0.68 7.65 2.66 95.68
12 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03 95.56
13 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29 95.56
14 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 92.28
15 INT158 Localization of Prl 2431 0.81 378.96 952.2 91.96
16 INT157720 Localization of ADHD1 15 0.64 15.84 1.69 88.96
17 INT68695 Gene_expression of HTT 63 0.77 44.54 3.69 88.04
18 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64 87.88
19 INT258760 Phosphorylation of ADHD1 1 0.25 0.98 0 85.68
20 INT320705 Gene_expression of PMVK 1 0.50 0.8 0.09 85.52
21 INT320707 Positive_regulation of C1QL3 1 0.02 0.3 0.03 85.16
22 INT157932 Positive_regulation of ADHD1 46 0.48 52.18 6.13 83.56
23 INT211905 Negative_regulation of RIOK3 2 0.07 2.25 0.48 82.68
24 INT304199 Negative_regulation of Positive_regulation of HP 1 0.04 1.72 0.08 80.40
25 INT91610 Binding of ZFP91 4 0.31 2.86 1.11 79.92
26 INT37215 Positive_regulation of SMN1 18 0.45 8.99 4.87 78.08
27 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 76.64
28 INT227500 Negative_regulation of Gene_expression of ADHD1 5 0.34 4.9 1.32 75.88
29 INT184852 Positive_regulation of Gene_expression of ADHD1 6 0.40 5.06 1.66 74.96
30 INT184857 Positive_regulation of Lmo1 4 0.23 4.59 2.03 74.48
31 INT317907 Gene_expression of DLGAP2 1 0.63 0.85 0 73.84
32 INT189862 Gene_expression of OSR1 2 0.10 3.62 0.04 72.56
33 INT81155 Localization of CDCP1 5 0.08 4.49 1.4 71.72
34 INT145364 Negative_regulation of AXIN1 2 0.33 0.52 0.08 68.48
35 INT294014 Regulation of AXIN1 3 0.24 1.04 0.08 68.48
36 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 68.00
37 INT50848 Regulation of ZFP91 5 0.38 2.45 0.35 66.40
38 INT321648 Regulation of Localization of Phc1 1 0.05 0.38 0 62.12
39 INT215946 Localization of Phc1 33 0.10 8.41 1.39 60.80
40 INT111100 Gene_expression of Dusp1 18 0.76 14.81 5.21 57.60
41 INT226221 Binding of Dusp1 1 0.04 0.92 0.68 53.36
42 INT120165 Binding of NTM 2 0.47 2.23 0.29 51.52
43 INT317915 Binding of SNX19 1 0.36 2.04 0.2 51.52
44 INT51897 Binding of OPCML 8 0.43 5.59 1.11 51.52
45 INT317919 Binding of VPS26B 1 0.23 0.93 0.1 51.52
46 INT317908 Binding of NCAPD3 1 0.32 0.91 0.1 51.52
47 INT317904 Binding of THYN1 1 0.32 0.96 0.1 51.52
48 INT14043 Binding of HP 52 0.30 26.56 7.76 48.44
49 INT18190 Regulation of DRD2 11 0.60 9.01 7.63 46.28
50 INT244343 Localization of NTM 16 0.73 14.26 0.26 46.16
51 INT72746 Localization of Avpr1a 4 0.73 2.54 0.73 45.44
52 INT255462 Binding of Avpr1a 8 0.47 2.41 1.61 44.40
53 INT193436 Localization of soc 5 0.65 2.17 0.15 42.64
54 INT317914 Localization of NCAPD3 1 0.65 0.88 0.1 41.04
55 INT135337 Gene_expression of PTPRN2 2 0.72 0.82 0 36.36
56 INT317911 Localization of VPS26B 1 0.47 0.88 0.1 36.32
57 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 35.56
58 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09 35.40
59 INT172622 Localization of EP300 8 0.65 2.56 1.72 35.20
60 INT61825 Negative_regulation of Slc6a3 47 0.59 6.52 21.27 34.96
61 INT245992 Binding of C1QL3 2 0.22 0.41 0 34.40
62 INT317903 Gene_expression of NCAPG2 1 0.64 1.56 0 34.12
63 INT139281 Gene_expression of VIPR2 3 0.74 0.88 0.2 32.72
64 INT51895 Localization of OPCML 6 0.68 3.43 0.54 32.08
65 INT317920 Localization of SNX19 1 0.73 1.88 0.2 32.08
66 INT317910 Localization of THYN1 1 0.65 0.88 0.1 32.08
67 INT317905 Gene_expression of ESYT2 1 0.64 0.76 0 30.72
68 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 30.00
69 INT871 Negative_regulation of Gene_expression of Prl 53 0.58 18.89 17.79 30.00
70 INT57549 Gene_expression of GNPTAB 49 0.65 57.5 9.05 28.96
71 INT317906 Gene_expression of WDR60 1 0.71 0.74 0 28.80
72 INT894 Binding of Avp 84 0.48 29.16 29.63 28.08
73 INT13501 Binding of Drd2 65 0.48 23.76 35.6 25.00
74 INT320708 Binding of PMVK 1 0.36 0.58 0.03 24.72
75 INT12484 Binding of Drd2 45 0.48 15.17 24.72 19.24
76 INT546 Binding of ALB 311 0.48 85.98 60.14 18.44
77 INT320703 Binding of SMARCC1 1 0.03 0.77 0 16.84
78 INT317912 Gene_expression of NCAPH2 1 0.06 0.74 0 11.96
79 INT320706 Positive_regulation of SMARCC1 1 0.06 0.97 0 9.36
80 INT114499 Gene_expression of MCPH1 38 0.67 26.68 4.55 5.84
81 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 5.00
82 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 5.00
83 INT162 Regulation of Prl 794 0.62 165.01 322.24 5.00
84 INT477 Localization of Avp 813 0.81 131.58 300.4 5.00
85 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 5.00
86 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 5.00
87 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 5.00
88 INT4658 Binding of OPRM1 188 0.48 25.96 136.24 5.00
89 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
90 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 5.00
91 INT7528 Regulation of OPRM1 100 0.62 20.63 80.57 5.00
92 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
93 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 5.00
94 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 5.00
95 INT96533 Gene_expression of Slc1a3 72 0.78 26.85 55.31 5.00
96 INT249 Localization of GHRH 215 0.80 78.02 51.87 5.00
97 INT5704 Binding of Slc3a1 78 0.43 8.52 51.78 5.00
98 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32 5.00
99 INT2783 Gene_expression of Slc3a1 86 0.65 8.84 45.4 5.00
100 INT5454 Localization of CRH 124 0.79 79.18 41.53 5.00
101 INT2531 Positive_regulation of Cebpz 166 0.00 43.08 38.86 5.00
102 INT163134 Gene_expression of ACR 78 0.65 30.39 38.48 5.00
103 INT16323 Gene_expression of pr 62 0.66 36.14 38.26 5.00
104 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 5.00
105 INT316 Regulation of Cebpz 105 0.00 27.21 35.41 5.00
106 INT6683 Gene_expression of Drd2 64 0.78 11.31 32.28 5.00
107 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 5.00
108 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 5.00
109 INT4868 Gene_expression of GAL 75 0.78 22.23 29.02 5.00
110 INT2650 Positive_regulation of Slc3a1 50 0.57 2.95 27.52 5.00
111 INT12392 Regulation of Slc3a1 45 0.36 7.57 25.66 5.00
112 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 5.00
113 INT519 Negative_regulation of Comt 52 0.59 17.65 20.39 5.00
114 INT7470 Positive_regulation of Gene_expression of Avp 37 0.70 19.55 19.96 5.00
115 INT14436 Gene_expression of Dbh 42 0.72 9.9 19.85 5.00
116 INT29555 Positive_regulation of CALM1 58 0.69 14.09 17.37 5.00
117 INT1721 Negative_regulation of HP 148 0.42 86.82 16.89 5.00
118 INT164366 Localization of NLRP1 26 0.71 5.9 16.54 5.00
119 INT984 Positive_regulation of Localization of GHRH 58 0.70 12.66 16.51 5.00
120 INT7952 Localization of Slc3a1 32 0.81 1.28 15.69 5.00
121 INT54356 Regulation of Slc6a3 48 0.58 5.86 15.24 5.00
122 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23 5.00
123 INT80685 Gene_expression of MAPK8 90 0.72 51.91 13.36 5.00
124 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43 5.00
125 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41 5.00
126 INT80790 Positive_regulation of Flvcr2 22 0.45 4.92 12.35 5.00
127 INT520 Binding of Comt 24 0.48 8.98 12.21 5.00
128 INT11141 Negative_regulation of Gene_expression of Avp 23 0.59 3.85 12.19 5.00
129 INT8548 Gene_expression of HP 86 0.77 47.62 11.94 5.00
130 INT7682 Binding of Drd1a 22 0.48 1.8 11.83 5.00
131 INT87698 Gene_expression of WAS 25 0.58 8.75 11.83 5.00
132 INT71633 Negative_regulation of SLC6A3 25 0.59 10.5 10.69 5.00
133 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4 5.00
134 INT25834 Positive_regulation of Dbp 59 0.68 24.34 9.32 5.00
135 INT13296 Transcription of Drd2 17 0.66 2.7 9.07 5.00
136 INT34268 Binding of WAS 14 0.47 4.41 8.67 5.00
137 INT82709 Negative_regulation of Slc37a4 17 0.34 3.41 8.6 5.00
138 INT184864 Gene_expression of Lmo1 16 0.26 8.09 8.48 5.00
139 INT148703 Gene_expression of NOVA2 73 0.65 18.05 8.3 5.00
140 INT87699 Positive_regulation of WAS 16 0.45 5.84 8.03 5.00
141 INT28457 Positive_regulation of Slc6a3 26 0.50 3.64 7.76 5.00
142 INT101414 Gene_expression of Phc1 27 0.60 9.55 7.58 5.00
143 INT10344 Localization of Jun 23 0.73 6.36 7.46 5.00
144 INT126314 Positive_regulation of OFC1 25 0.54 7.65 7.39 5.00
145 INT20922 Positive_regulation of Localization of CRH 18 0.67 11.12 6.79 5.00
146 INT90461 Negative_regulation of DRD2 21 0.53 8.35 6.55 5.00
147 INT79822 Gene_expression of Htr1b 10 0.65 2.92 6.27 5.00
148 INT84965 Gene_expression of MAOA 15 0.75 6.9 6.06 5.00
149 INT17641 Gene_expression of NLRP1 33 0.73 8.85 6.02 5.00
150 INT103880 Positive_regulation of DRD2 9 0.67 5.57 5.93 5.00
151 INT129508 Localization of Cacna1a 7 0.74 6.47 5.13 5.00
152 INT71418 Binding of CES1 42 0.40 29.78 5.01 5.00
153 INT94095 Negative_regulation of BCAT1 9 0.49 0.97 4.91 5.00
154 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86 5.00
155 INT23045 Positive_regulation of Hbb 31 0.64 19.35 4.54 5.00
156 INT84911 Gene_expression of SUGT1 43 0.11 19.85 4.54 5.00
157 INT168418 Positive_regulation of RCT 32 0.55 20.2 4.07 5.00
158 INT119053 Positive_regulation of SLC6A3 15 0.65 2.51 4 5.00
159 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95 5.00
160 INT179261 Gene_expression of SERPINA6 12 0.14 3.53 3.82 5.00
161 INT103021 Transcription of Slc6a4 16 0.70 3.93 3.77 5.00
162 INT76625 Positive_regulation of Phc1 14 0.36 5.1 3.49 5.00
163 INT165811 Binding of Phc1 13 0.15 5.99 3.09 5.00
164 INT65916 Gene_expression of LAMB1 13 0.55 3.09 3.06 5.00
165 INT88273 Gene_expression of Drd4 6 0.54 1.84 3.01 5.00
166 INT161960 Regulation of lg 5 0.26 1.18 2.84 5.00
167 INT187499 Positive_regulation of Positive_regulation of Fig4 9 0.21 3.28 2.69 5.00
168 INT257950 Regulation of Localization of NLRP1 3 0.08 0.27 2.6 5.00
169 INT128983 Protein_catabolism of Comt 5 0.87 0.22 2.6 5.00
170 INT122976 Binding of Datd 7 0.33 3.99 2.59 5.00
171 INT62153 Regulation of Datd 4 0.27 0.38 2.5 5.00
172 INT168913 Negative_regulation of Avpr1a 7 0.43 5.88 2.47 5.00
173 INT152163 Positive_regulation of GALR2 4 0.70 3.69 2.43 5.00
174 INT61686 Positive_regulation of Gene_expression of Slc3a1 5 0.24 1.74 2.13 5.00
175 INT123843 Gene_expression of soc 14 0.58 5.22 1.96 5.00
176 INT193415 Positive_regulation of GALR1 1 0.36 2.27 1.66 5.00
177 INT193416 Positive_regulation of GALR3 1 0.31 2.25 1.65 5.00
178 INT98788 Negative_regulation of EPHB1 11 0.37 3.65 1.64 5.00
179 INT174107 Binding of Plxna3 4 0.21 2.95 1.62 5.00
180 INT81726 Binding of soc 42 0.42 9.92 1.61 5.00
181 INT53008 Gene_expression of Nr4a2 25 0.74 4.89 1.5 5.00
182 INT212466 Regulation of EPHB1 7 0.37 5.72 1.42 5.00
183 INT159423 Binding of ANKK1 4 0.47 0.9 1.35 5.00
184 INT152167 Regulation of GALR2 2 0.44 2.23 1.33 5.00
185 INT76596 Gene_expression of BCAT1 5 0.58 0.73 1.32 5.00
186 INT61999 Gene_expression of MAPT 19 0.75 15.4 1.3 5.00
187 INT119283 Binding of DRD1 3 0.33 0.95 1.23 5.00
188 INT10117 Positive_regulation of INSR 10 0.43 4.71 1.22 5.00
189 INT166274 Gene_expression of EPHB1 14 0.55 8.2 1.19 5.00
190 INT145488 Regulation of Cyp2d4 5 0.45 1.1 1.19 5.00
191 INT77216 Localization of DRD2 3 0.75 0 1.19 5.00
192 INT105425 Binding of BCAT1 5 0.42 0.78 1.17 5.00
193 INT39818 Positive_regulation of Cfd 8 0.45 3.36 1.15 5.00
194 INT169643 Binding of Ods 3 0.18 2.89 1.15 5.00
195 INT58211 Gene_expression of FURIN 7 0.57 0.62 1.15 5.00
196 INT202579 Regulation of Gene_expression of DRD2 4 0.41 1.11 0.99 5.00
197 INT321650 Negative_regulation of Gene_expression of Cacna1a 2 0.04 0.13 0.95 5.00
198 INT290728 Gene_expression of Depmq1 1 0.01 0.79 0.92 5.00
199 INT255461 Positive_regulation of Avpr1a 3 0.45 1.3 0.91 5.00
200 INT96649 Gene_expression of ARSA 5 0.65 2.82 0.8 5.00
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