D:Convalescence

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Disease Term
Synonyms CONVALESCENCES
Documents 585
Hot Single Events 119
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Convalescence. They are ordered first by their relevance to Convalescence and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT316538 Lvs Positive_regulation of Gene_expression of Il17a 1 0.30 1.3 0.21 92.44
2 INT279530 MBL2 Positive_regulation of Positive_regulation of C3 1 0.26 1.71 0 62.08
3 INT279534 Binding of CFH and PTPN11 1 0.02 2.54 0 58.80
4 INT186373 Il6 Positive_regulation of Gene_expression of Il17a 2 0.14 1.52 0.42 54.40
5 INT279537 ICAM3 Positive_regulation of C3 1 0.06 0.85 0 28.80
6 INT279533 CFH Positive_regulation of C3 1 0.07 1.8 0 25.52
7 INT279535 Binding of C1QC and MBL2 1 0.01 2.79 0 25.20
8 INT284677 IFNG Negative_regulation of IL4 1 0.01 0.98 0.18 22.76
9 INT241300 Binding of IGHG3 and PTPN11 1 0.01 1.47 0 11.20
10 INT279539 Binding of CFD and MBL2 1 0.09 0.08 0 9.60
11 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 5.00
12 INT272984 Il6 Positive_regulation of Gene_expression of Itgam 1 0.24 0.78 0.96 5.00
13 INT329722 Binding of Il10rb and Il10 1 0.00 0.79 0.51 5.00
14 INT329721 Positive_regulation of Binding of Il10rb and Il10 1 0.00 0.79 0.51 5.00
15 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 5.00
16 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46 5.00
17 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46 5.00
18 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38 5.00
19 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33 5.00
20 INT217349 Mip Positive_regulation of IL8 1 0.05 1.28 0.22 5.00
21 INT318303 Negative_regulation of Myoz1 Negative_regulation of Transcription of IL2 1 0.00 0.75 0.21 5.00
22 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18 5.00
23 INT316535 Il23a Regulation of Il12a 1 0.07 1.15 0.15 5.00
24 INT185644 Binding of STATH and WASF1 1 0.00 0 0.09 5.00
25 INT316539 Il17a Positive_regulation of Gene_expression of Lvs 1 0.22 1.02 0.08 5.00
26 INT186860 MIR181A2HG Regulation of Cd86 1 0.02 1.05 0.07 5.00
27 INT186814 MIR181A2HG Regulation of ICAM1 1 0.01 1.05 0.07 5.00
28 INT222295 Binding of CPP and Cebpz 1 0.00 0.73 0.05 5.00
29 INT279536 Binding of C1QC and CRP 1 0.01 0.59 0.04 5.00
30 INT279531 Binding of LPA and MBL2 1 0.02 0.54 0.04 5.00
31 INT315678 Binding of MPZ and UPF1 1 0.00 2.05 0.04 5.00
32 INT245218 Binding of C3 and C5AR1 2 0.29 2.94 0.04 5.00
33 INT279538 Binding of C4B and Positive_regulation of ENPEP 1 0.00 0.48 0.03 5.00
34 INT279593 Binding of C4B and Cfb 1 0.00 1.18 0.03 5.00
35 INT329729 Binding of LCK and Fyn 1 0.00 0.21 0.03 5.00
36 INT217317 Binding of polymerase and SUMO1 1 0.00 1.7 0 5.00
37 INT294065 ANGPT2 Positive_regulation of VEGFA 1 0.02 0.1 0 5.00
38 INT217316 Binding of SUMO1 and ERVW-1 1 0.00 1.55 0 5.00
39 INT294066 ANGPT1 Positive_regulation of VEGFA 1 0.01 0.1 0 5.00
40 INT233770 RCT Negative_regulation of MCO 1 0.01 0 0 5.00
41 INT316537 Binding of Tlr1 and Il23a 1 0.12 0.78 0 5.00
42 INT323332 Binding of Ighm and Chd7 1 0.02 0 0 5.00
43 INT217314 IFNA1 Positive_regulation of MAVS 1 0.01 1.47 0 5.00
44 INT323333 Binding of Ighm and Ict1 1 0.02 0 0 5.00
45 INT316536 Binding of Tlr2 and Il23a 1 0.11 0.78 0 5.00
46 INT279592 Positive_regulation of Binding of C4B and Cfb 1 0.00 0.74 0 5.00
47 INT217315 Binding of UBE2I and ERVW-1 1 0.01 1.56 0 5.00
48 INT279540 Binding of C4B and ENPEP 1 0.00 0.82 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Convalescence. They are ordered first by their pain relevance and then by number of times they were reported in Convalescence. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT329717 Negative_regulation of Psmd1 1 0.04 0.69 0 100.00
2 INT329715 Negative_regulation of Prdx6 1 0.06 0.69 0 100.00
3 INT193439 Localization of MCO 1 0.61 0.49 0.08 100.00
4 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.40
5 INT20205 Binding of IgG 108 0.46 66.68 8.57 99.38
6 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 99.12
7 INT71376 Positive_regulation of Gene_expression of Prf1 1 0.03 1.08 0.98 98.88
8 INT1829 Gene_expression of CFH 71 0.75 64.24 2.49 98.76
9 INT186840 Regulation of FCGR1B 4 0.15 2.67 0 98.76
10 INT186854 Regulation of EBNA1BP2 1 0.03 1.5 0 98.76
11 INT198607 Regulation of Gene_expression of CFH 2 0.27 2.16 0 98.76
12 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 98.64
13 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 98.48
14 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 98.40
15 INT14384 Gene_expression of Prf1 9 0.60 3.03 2.22 98.28
16 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 98.28
17 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 98.28
18 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 98.28
19 INT5148 Regulation of CD40LG 25 0.44 21.58 4.05 98.12
20 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 98.00
21 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 97.92
22 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 97.92
23 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 97.60
24 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 97.60
25 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 97.52
26 INT180695 Regulation of Timp2 2 0.21 0.67 0.05 97.48
27 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 97.40
28 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 96.60
29 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 96.48
30 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 96.04
31 INT9210 Regulation of IL6 166 0.62 125.61 49.95 96.00
32 INT202715 Binding of NMS 3 0.27 6.92 0.65 95.84
33 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 95.76
34 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 95.76
35 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 95.72
36 INT119827 Gene_expression of PTPN11 31 0.75 24.21 1.22 95.72
37 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 95.64
38 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 95.64
39 INT279582 Positive_regulation of C1QC 3 0.02 2.62 0 95.64
40 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 95.48
41 INT22454 Regulation of Crp 213 0.62 160.67 49.24 94.92
42 INT91320 Localization of Hmox1 8 0.81 4.06 1.28 94.76
43 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 94.48
44 INT329704 Localization of Il10rb 1 0.05 0.63 0 94.48
45 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 94.08
46 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 94.00
47 INT39301 Gene_expression of Chd7 50 0.26 27.06 8.13 93.92
48 INT88613 Localization of Il1r2 3 0.32 1.17 0.89 93.88
49 INT186662 Gene_expression of C1QC 3 0.46 10.44 0.23 93.68
50 INT277241 Localization of Serpinb2 2 0.21 1.27 0 93.60
51 INT186850 Binding of EBNA1BP2 10 0.39 2.9 0 93.48
52 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 93.24
53 INT107924 Localization of Tnfrsf1a 5 0.70 3.86 1.37 92.68
54 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 92.60
55 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 92.60
56 INT155010 Positive_regulation of Gene_expression of IL17A 23 0.64 20.17 7.15 92.60
57 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 92.52
58 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 92.28
59 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 91.92
60 INT89941 Positive_regulation of Il1r2 4 0.49 1.92 2.43 91.76
61 INT125775 Positive_regulation of Serpinb2 7 0.36 3.81 0.9 91.76
62 INT70666 Positive_regulation of CLU 16 0.45 12.95 0.74 91.76
63 INT241303 Localization of PTPN11 8 0.77 10.23 0.06 91.36
64 INT241301 Positive_regulation of Localization of PTPN11 1 0.45 2.78 0 91.36
65 INT186837 Gene_expression of EBNA1BP2 9 0.64 8.66 0.13 91.32
66 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 90.80
67 INT125480 Regulation of HHIP 17 0.38 6.16 2.16 90.80
68 INT233766 Negative_regulation of Regulation of HHIP 1 0.12 0.32 0 90.80
69 INT79956 Positive_regulation of Positive_regulation of C3 4 0.35 4.17 0.86 90.40
70 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 90.40
71 INT59319 Negative_regulation of Positive_regulation of Il4 6 0.57 3.48 1.17 89.48
72 INT316524 Negative_regulation of Positive_regulation of Il13 2 0.34 1.87 0.45 89.48
73 INT177346 Negative_regulation of Positive_regulation of Il5 2 0.28 1.12 0.27 89.48
74 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 89.36
75 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 89.08
76 INT316529 Protein_catabolism of Il17a 2 0.82 2.21 0.26 89.00
77 INT10835 Regulation of IL8 79 0.49 53.04 24.14 88.88
78 INT15796 Regulation of IL2 66 0.61 25.43 20.62 88.88
79 INT73497 Regulation of IL10 33 0.45 22.6 9.19 88.88
80 INT171562 Regulation of IL4 19 0.36 12.12 5.33 88.88
81 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 88.72
82 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 88.24
83 INT304439 Positive_regulation of Xist 2 0.01 1.56 0.56 88.24
84 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 88.24
85 INT100938 Positive_regulation of Il13 47 0.69 42.11 14.36 88.24
86 INT97439 Positive_regulation of Il5 46 0.60 25.6 9.47 88.24
87 INT100671 Positive_regulation of Transcription of Hand2 2 0.36 0.81 0.23 88.24
88 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15 87.92
89 INT100672 Transcription of Hand2 9 0.42 2.84 1.47 87.72
90 INT274751 Localization of Mpeg1 4 0.05 4.16 2.9 86.84
91 INT12339 Localization of IL8 437 0.81 251.87 117.39 86.56
92 INT12082 Localization of IL6 365 0.81 241.78 105.78 86.56
93 INT10763 Localization of IL2 157 0.80 81.11 33.21 86.56
94 INT74423 Localization of IL10 91 0.80 61.6 22.95 86.56
95 INT69158 Localization of IL4 48 0.71 31.3 11.98 86.56
96 INT233768 Regulation of MCO 1 0.23 0.3 0 86.08
97 INT233767 Positive_regulation of Regulation of MCO 1 0.25 0.3 0 86.08
98 INT172078 Localization of Cd3e 22 0.37 9.88 2.27 85.88
99 INT182455 Localization of Klrb1c 2 0.73 1.65 0.04 85.88
100 INT251238 Gene_expression of Lvs 35 0.32 29.41 1.59 85.80
101 INT104031 Regulation of ENPEP 18 0.33 13.48 1.69 84.72
102 INT116867 Positive_regulation of Gene_expression of CFH 11 0.67 11.42 0.3 84.72
103 INT198603 Positive_regulation of Transcription of CFH 2 0.50 2 0 84.72
104 INT316526 Localization of Flg 1 0.35 0.85 0.12 84.20
105 INT316527 Positive_regulation of Localization of Flg 1 0.22 0.86 0.12 84.20
106 INT198598 Transcription of CFH 3 0.69 3.21 0.05 84.12
107 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 84.04
108 INT217344 Gene_expression of RSAD2 13 0.22 17.78 0.27 83.20
109 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 83.20
110 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47 82.80
111 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 81.60
112 INT207780 Positive_regulation of NMS 2 0.28 3.2 0.61 81.60
113 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 81.04
114 INT247102 Binding of MBL2 16 0.38 14.18 1.54 80.80
115 INT43931 Binding of CFH 49 0.48 31.85 3.96 80.80
116 INT279572 Gene_expression of MBL2 27 0.64 20.88 1.51 80.80
117 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 80.68
118 INT164048 Positive_regulation of SMARCAL1 2 0.40 0.33 0.12 80.68
119 INT24020 Positive_regulation of HPS1 6 0.44 6.14 1.08 80.08
120 INT74786 Regulation of Gene_expression of IL5 7 0.45 4.85 3.54 79.52
121 INT94084 Regulation of Gene_expression of IL13 6 0.22 3.55 1.9 79.52
122 INT279528 Gene_expression of Cic 1 0.75 3.07 0 78.80
123 INT193438 Binding of MCO 1 0.39 1.77 0.06 78.68
124 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 77.80
125 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 77.80
126 INT329713 Gene_expression of Prdx6 1 0.12 1.12 0.07 77.60
127 INT329714 Positive_regulation of Gene_expression of Prdx6 1 0.11 1.12 0.07 77.60
128 INT103289 Binding of Il10 15 0.35 13.67 7.42 77.40
129 INT189791 Negative_regulation of Gene_expression of Cd14 9 0.40 4.2 0.82 77.08
130 INT135022 Gene_expression of Cd14 79 0.76 36.37 10.63 76.36
131 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 75.92
132 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 75.92
133 INT99298 Positive_regulation of ITGA3 6 0.06 2.94 1.54 75.68
134 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 75.44
135 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25 75.44
136 INT27878 Gene_expression of FCGR1B 22 0.26 20.62 2.04 75.44
137 INT19432 Positive_regulation of Gene_expression of CD79A 14 0.45 13.49 1.49 75.44
138 INT27883 Positive_regulation of FCGR1B 5 0.10 6.15 0.97 75.44
139 INT67401 Gene_expression of Il12a 25 0.55 20.04 11.12 75.00
140 INT49994 Gene_expression of Lta 9 0.64 6.94 2.98 75.00
141 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 75.00
142 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 75.00
143 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 75.00
144 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5 75.00
145 INT71374 Positive_regulation of Gene_expression of Il12a 5 0.22 7.49 3.8 75.00
146 INT49991 Positive_regulation of Gene_expression of Lta 4 0.40 2.03 1.41 75.00
147 INT36443 Regulation of Trf 4 0.61 1.65 1.18 75.00
148 INT71378 Transcription of LBR 2 0.07 1.34 1.03 75.00
149 INT71375 Transcription of Pmp2 1 0.15 1.08 1.01 75.00
150 INT217329 Positive_regulation of Gene_expression of RSAD2 1 0.19 11.98 0.41 74.96
151 INT1123 Positive_regulation of CD79A 74 0.70 51.96 7.14 74.92
152 INT23104 Positive_regulation of Cga 20 0.70 10.35 8.03 72.96
153 INT279580 Positive_regulation of Binding of MBL2 4 0.48 2.15 0.08 71.60
154 INT279576 Positive_regulation of MBL2 4 0.38 4.1 0 71.60
155 INT251239 Positive_regulation of Gene_expression of Lvs 4 0.21 7.64 0.86 70.88
156 INT161310 Negative_regulation of LCK 17 0.42 8.75 2.74 70.72
157 INT248588 Gene_expression of LCK 9 0.28 4.9 0.98 70.72
158 INT82546 Negative_regulation of Gene_expression of CD69 5 0.47 2.69 0.68 70.08
159 INT173921 Negative_regulation of CD69 3 0.34 2.63 0.25 70.08
160 INT11048 Gene_expression of CD69 59 0.67 42.85 6.4 70.08
161 INT138543 Negative_regulation of Cd28 3 0.11 2.1 1.01 69.60
162 INT93728 Gene_expression of Cd28 8 0.35 7.11 0.59 69.60
163 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39 69.12
164 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18 69.00
165 INT251659 Positive_regulation of Prdx6 2 0.11 2.07 0.36 69.00
166 INT326613 Negative_regulation of Transcription of APBB1IP 1 0.09 0.42 0 68.32
167 INT326612 Transcription of APBB1IP 1 0.15 0.42 0 68.32
168 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 68.16
169 INT180734 Gene_expression of Emid1 3 0.65 6.83 0.21 67.68
170 INT15172 Positive_regulation of Itgam 45 0.67 23.54 10.3 67.44
171 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 67.40
172 INT279781 Gene_expression of MAVS 4 0.15 3.51 0.12 67.36
173 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 67.12
174 INT102272 Regulation of TH1L 41 0.44 30.89 11.63 67.12
175 INT185412 Negative_regulation of CFD 5 0.27 3.49 0.2 66.48
176 INT279586 Negative_regulation of Gene_expression of CFD 3 0.20 3.99 0.16 66.48
177 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 65.00
178 INT209993 Transcription of LRP1 2 0.33 0.41 0 63.76
179 INT326611 Negative_regulation of Transcription of LRP1 1 0.21 0.41 0 63.76
180 INT279581 Regulation of VTN 1 0.01 0.18 0 63.76
181 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 63.52
182 INT150022 Positive_regulation of Il17a 69 0.64 70.04 21.87 62.80
183 INT236349 Positive_regulation of Positive_regulation of Il17a 7 0.46 5.96 1.67 62.80
184 INT47503 Gene_expression of HPS1 12 0.58 7.96 2.7 61.44
185 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 61.40
186 INT94335 Positive_regulation of CXCL10 71 0.58 50.69 23 61.40
187 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8 61.40
188 INT846 Positive_regulation of B2M 42 0.70 29.78 8.06 61.40
189 INT137177 Positive_regulation of CXCL11 6 0.67 4.17 1.13 61.40
190 INT217340 Positive_regulation of DIRAS1 1 0.02 0.47 0 61.40
191 INT217333 Positive_regulation of TNFAIP3 3 0.23 2.65 0 61.40
192 INT54763 Binding of Il6 82 0.48 63.27 12.89 59.96
193 INT2383 Positive_regulation of CP 33 0.67 25.41 15.38 59.76
194 INT115831 Transcription of Hmox1 16 0.66 5.31 1.14 59.20
195 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 58.28
196 INT3593 Gene_expression of ADRA1D 70 0.75 29.48 20.87 57.84
197 INT126030 Regulation of CFD 4 0.21 3.92 0.83 57.44
198 INT279571 Regulation of Gene_expression of CFD 2 0.21 2.86 0.31 57.44
199 INT241305 Binding of PTPN11 9 0.46 6.08 0.1 56.64
200 INT16385 Regulation of C3 20 0.41 9.98 1.92 56.44
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